Large-scale Protein Production Service
With the rapid growth of the protein drug market and recent advances in proteomics, the supply of large quantities of pure, active proteins has become essential for the production of protein drugs and to the development of drug assays and research methods. GenScript is fully equipped to meet this need for large-scale protein production service. Our versatile and reliable protein expression system, which includes fermentors, wave mixers, and bioreactors, combined with our large-scale purification service, allows GenScript to provide its clients in both the public and private research sectors, academia, and all levels of the pharmaceutical industry with protein orders as large as grams. GenScript has delivered more than 500 proteins, including 300 grams of protein on a single project.
Capabilities of Different Expression Systems:
| Bacteria | Yeast | Insect Cells | Mammalian Cells |
| 1,000 L |
500 L |
500 L |
300 L |
| Fermentor |
Fermentor |
WaveTM Mixer |
WaveTM Mixer |
Capabilities Specifications:
| Expression System | Capabilities | Equipment |
| Bacteria |
- Provides transformed bacterial paste for large-scale fermentation, up to three metric tons.
- Provides homogeneous recombinant proteins, over 98% pure, for crystallization, and partially purified recombinant proteins, over 70% pure.
- Provides large quantities of protein, up to grams
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Fermentor
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| Yeast |
- Provides yeast cell pellets transformed for large-scale fermentation, up to three metric tons.
- Provides homogeneous recombinant proteins, over 98% pure, for crystallization.
- Provides partially purified recombinant proteins, over 70% pure.
- Provides large quantities of protein, up to grams.
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| Baculovirus-Insect Cells |
- Provides purified, high titer recombinant baculovirus stock, of up to 109 pfu/ml, carrying the customer's gene.
- Provides homogeneous recombinant proteins, over 98% pure, for crystallization.
- Provides partially purified recombinant proteins, over 70% pure.
- Provides large quantities of protein, up to grams.
- Provides a large-scale protein production option, up to few hundreds of mg, using insect cells and a wave mixer system.
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WaveTM Mixer  |
| Mammalian Cells |
- Provides one single system for the production of final homogeneous recombinant proteins, from gene synthesis to expression, for orders of up to 100 mg.
- Permits transient expression of customers' proteins of interest, up to 10 mg in 10 days.
- Provides conditioned media and cell pellets from stable cell lines, up to 300 L, using a wave mixer system.
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Quotations and Ordering:
 To request a quotation, please download and complete the Quotation/Order Form, and send it to us by email or fax.
To order, please download and complete the Quotation/Order Form and send it to us by email or fax with a formal PO (Purchase Order) or credit card information. You can also submit PO/credit card information by phone or via our secure online messaging system.
If submitting samples, please mail them together with a hard copy of the completed Quotation/Order Form to: Protein Services, GenScript, 120 Centennial Ave., Piscataway, NJ 08854, US.
For questions, or to inquire about the status of your order contact us by email, phone, fax or via our secure online messaging system.
Our customer service representatives are available 24 hours a day, Monday through Friday to assist you.
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Email: protein@genscript.com |
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Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188 |
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Fax: 1-732-210-0262 1-732-885-5878 |
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