Protein Services

Active, purified proteins that can sustain functional analysis and assay development are critical to the discovery of drug targets and therapeutic proteins. However, many of these active proteins, particularly emerging and newly discovered candidates, are not commercially available and thus have to be custom made. GenScript offers a complete industrial solution for all protein expression and purification issues. GenScript's multiple protein expression systems are available on both small and large scales. Proteins that require glycosylation may be best suited to our insect and mammalian expression systems. Our large scale-up capabilities provide pharmaceutical customers with high-purity active proteins of any quantity for target discovery, target validation, high-throughput screening (HTS), and structure-function studies. Our streamlined processes apply multiple approaches to expression optimization and allow us to offer highly competitive prices on custom protein projects.

Services and Key Features:

Diverse expression systems: Bcterial Yeast Baculovirus/insect Mammalian Large-scale protein production services: Fermentors Wave systemTM Bioreactors High-expression, stable cell lines in yeast, insect and mammals Recombinant baculovirus generation Membrane preparation Large-volume transient transfection Large-volume frozen transients for high-throughput screening (HTS) Multiple protein purification options: Affinity column (GST, Ni-IDA, protein A, G, or L resins) Gel filtration Ion exchange Hydrophobic column HPLC