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Epitope Mapping Service
Antibody Sequencing Quotation

Epitope Mapping Service

Epitope mapping has become more and more vital in both vaccine and antibody drug development. Knowledge on epitope of an antibody will largely facilitate your drug design and patent application. Based on our advanced peptide library platform, GenScript provides a comprehensive series of Epitope Mapping Services (Cat. No: SC1500) to fulfill customers' demand.

Key Features

Epitope Mapping Service (Cat. No.: SC1500)

Service Includes Description Delivery Time
Binding activity test ELISA/WB confirm the binding of submitted antigen and antibody
4-6 weeks
Glycosylation analysis (optional) Compare the antibody-antigen binding activity of deglycosylation antigen with the submitted antigen
Overlapping peptide library Overlapping peptides are synthesized according to the protein sequences provided by the customer.
Detection Screening of peptide library against customer samples: control detection (optional) and target detection.

Client provides

Customer should submit the antigen sequence, antigen sample, target antibody sample, and control antibody sample (optional) for the services. Please submit the samples according to the requirements suggested below.

  • Antigen sequence: Please submit the sequence of your antigen via our Secure Online Messaging System, or send the sequence along with the epitope mapping quotation form by email.
  • Antigen samples: Please mail about 10μg of antigen samples (dissolved in PBS, pH 8.0-8.5, shipped at -20℃) to detect the binding activity between antigen and antibody samples.
  • Antibody samples: Please mail 100μg of samples. (powder shipped at 2-8℃, or dissolved in PBS, pH 8.0-8.5, shipped at -20℃)

GenScript delivers

The final report includes details of work performed and data analysis on epitope alignment.

Additional Services for Epitope Optimization

GenScript's rapid high-throughput parallel peptide library platform can provide following services to optimize your epitope:
Truncation library: Determine the minimum length required for epitope activity
Alanine scanning: Identify specific residues responsible for the epitope's function
Substitutional analysis: Functional characterization of epitopes
Moreover, our powerful peptide library design tools can facilitate your epitope optimization.

GenScript offers our customers a one-stop solution for all outsourcing needs, providing comprehensive upstream and downstream services of epitope mapping service.

 

Quotation and Ordering

 
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