GenScript celebrates the accomplishments of the winners of the 2013 Nobel Prize in Physiology or Medicine. James Rothman, Randy Schekman, and Thomas Südhof shared the prize for their discoveries of the mechanisms of vesicle trafficking, a major transport system within cells that is crucial for the regulated secretion of neurotransmitters and other critical biomolecules.
April 25, 2013 marks the 60th anniversary of Watson and Crick's seminal publication on the structure of the DNA double helix. Much of the research in the first 50 years after this publication has been focused on understanding the how DNA encodes for the macromolecules that sustain life. However, the past 10 years, have ushered in a new era in DNA history, in which the use of synthetic DNA has become more and more prevalent. Affordable access to synthetic DNA has not only accelerated basic biological research, but it also has allowed us to engineer useful biological systems using a ground-up approach, from optimizing valuable metabolic pathways to creating de novo functional genomes.