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ExpressPatch hERG Safety Testing Service

ExpressPatch hERG Safety Testing Service (SC1514)

As more and more drugs candidates are awaiting cardiac safety hERG testing, the throughput of manual patch clamp technology is becoming the bottleneck. Several automated patch clamp technologies abiding by the same principle with manual patch clamp have been developed and can increase the throughput dramatically and maintain the data quality. Moreover, the automated patch clamp platforms are undertaking an ever increasing role in ion channel drug discovery.

GenScript has established automated patch clamp platform utilizing QPatch 16 and offers ExpressPatch testing services to meet your demand for a higher throughput and lower cost of patch clamp recording than manual patch clamp. GenScript’s well validated hERG assay on QPatch 16 provides high quality data with a competitive cost.

Well-Validated QPatch 16 Platform
Cat. No. Service
Price (USD)
SC1514
ExpressPatch hERG Safety Testing Service
Quotation

Service Detail

Ion Channel hERG (hKv11.1)
Cell Line CHO
Technology Automated patch clamp (QPatch 16)
Sample Size Minimum pre-weighed 3 mg or 500 μl of 10mM in 100% DMSO
Note: 3 - 5 mg is enough for low molecular weight (MW < 500).
Compound Information Please offer molecular weight, solubility, and stablity information.
If the compound(s) are not soluble in 100% DMSO, please offer any useful information concerning the solubility.
Test Concentrations 5 conc. at n = 2 ($600/compound); 4 conc. at n = 3 ($800/compound)
Positive Control Terfenadine
Deliverables Report includes protocol summary, plus concentration-response curve and IC50 value if available.
Turnaround Time 1 week

Quotations and Ordering:

To request a quotation, please download and complete the and send it back by email or fax.

To order, please send the completed Quotation Form to us by email or fax with a formal PO (Purchase Order) or credit card information. You can also submit PO/credit card information by phone or via our Secure Online Messaging System.

Our customer service representatives are available 24 hours a day, Monday through Friday to assist you.

Order by email Email: bioassay@genscript.com
Order by phone Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Order by fax Fax: 1-732-210-0262 1-732-885-5878