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Fibroblast Growth Factor-1 (FGF-1, FGF-acidic), mouse
| Full Name |
Fibroblast Growth Factor-1 (FGF-1, FGF-Acidic), Mouse
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Abbreviated Name-1 |
FGF-acidic; HBGF-1 |
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Description |
FGF-acidic, also known as FGF-1, ECGF, and HBGF-1, is a 17 kDa nonglycosylated member of the FGF family of mitogenic peptides. FGF acidic, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors.
GenScipt Recombinant Mouse Fibroblast Growth Factor-acidic produced in E. coli is a non-glycosylated polypeptide chain containing 140 amino acids and having a molecular mass of 15,796 Da. |
M.W. |
15,796 Da |
Storage |
Lyophilized rmFGF-acidic although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution rmFGF-acidic should be stored at 4°C between 2-7 days and for future use below -18°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze-thaw cycles. |
Formulation |
The protein was lyophilized after extensive dialysis against 20mM Phosphate buffer, pH6.6, 500mM NaCl buffer. |
Reconstitution |
It is recommended to reconstitute the lyophilized rmFGF-acidic in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
Note |
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Document-MSDS: 15116_20111229220807.PDF (PDF)