| Gene Symbol | CIAO1 |
| Entrez Gene ID | 9391 |
| Full Name | cytosolic iron-sulfur assembly component 1 |
| Synonyms | CIA1,WDR39 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
gRNAs
The following CIAO1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CIAO1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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| CloneID | OHu15168 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_004804.2 , NM_004804.3 | |
| Accession Version | NM_004804.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1020bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-15 | |
| Organism | Homo sapiens(human) | |
| Product | probable cytosolic iron-sulfur protein assembly protein CIAO1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI460314.1, BC032812.1, AK124703.1, BE220199.1, BG108391.1 and AI094333.1. On Dec 1, 2003 this sequence version replaced NM_004804.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.4632.1, SRR1803613.194897.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAAGGACT CGCTGGTGCT GCTGGGCCGT GTCCCGGCGC ACCCGGACTC CCGCTGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_004795.1 |
| CDS | 206..1225 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_004804.2 |
1 | ATGAAGGACT CGCTGGTGCT GCTGGGCCGT GTCCCGGCGC ACCCGGACTC CCGCTGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu15168 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_004804.2 , NM_004804.3 | |
| Accession Version | NM_004804.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1020bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-10 | |
| Organism | Homo sapiens(human) | |
| Product | probable cytosolic iron-sulfur protein assembly protein CIAO1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI460314.1, BC032812.1, AK124703.1, BE220199.1, BG108391.1 and AI094333.1. On May 17, 2019 this sequence version replaced NM_004804.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.4632.1, SRR1803611.196354.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000488633.2/ ENSP00000418287.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAAGGACT CGCTGGTGCT GCTGGGCCGT GTCCCGGCGC ACCCGGACTC CCGCTGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_004795.1 |
| CDS | 127..1146 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_004804.3 |
1 | ATGAAGGACT CGCTGGTGCT GCTGGGCCGT GTCCCGGCGC ACCCGGACTC CCGCTGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu105008 | |
| Clone ID Related Accession (Same CDS sequence) | XM_024453247.1 | |
| Accession Version | XM_024453247.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-05 | |
| Organism | Homo sapiens(human) | |
| Product | probable cytosolic iron-sulfur protein assembly protein CIAO1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAAGGACT CGCTGGTGCT GCTGGGCCGT GTCCCGGCGC ACCCGGACTC CCGCTGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_024309015.1 |
| CDS | 193..1311 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_024453247.1 |
1 | ATGAAGGACT CGCTGGTGCT GCTGGGCCGT GTCCCGGCGC ACCCGGACTC CCGCTGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cytosolic HSC20 integrates de novo iron-sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients. |
Cellular requirements for iron-sulfur cluster insertion into the antiviral radical SAM protein viperin. |
Architecture of the human interactome defines protein communities and disease networks. |
The CIA Targeting Complex Is Highly Regulated and Provides Two Distinct Binding Sites for Client Iron-Sulfur Proteins. |
Human DNA polymerase ? is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19. |
