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VEGFA cDNA ORF clone, Bos taurus (cattle)

Gene Symbol VEGFA
Entrez Gene ID 281572
Full Name vascular endothelial growth factor A
Synonyms VEGF, VEGF-A, VPF, eVEGF120, eVEGF164
General protein information
Preferred Names
vascular endothelial growth factor A
Names
vascular endothelial growth factor A
vascular permeability factor
vascular endothelial growth factor 164
Gene Type protein-coding
Organism Bos taurus (cattle)
Genome

23

Summary lac of sum
Disorder MIM:

Disorder Html:

mRNA and Protein(s)

mRNA Protein Name
XM_005223556 XP_005223613 vascular endothelial growth factor A isoform X1
NM_174216 NP_776641 vascular endothelial growth factor A precursor

KEGG
bta04060 Cytokine-cytokine receptor interaction
bta04150 mTOR signaling pathway
bta04370 VEGF signaling pathway
bta04510 Focal adhesion
bta05200 Pathways in cancer
bta05211 Renal cell carcinoma
bta05212 Pancreatic cancer
bta05219 Bladder cancer
bta05323 Rheumatoid arthritis
bta04151 PI3K-Akt signaling pathway
bta04066 HIF-1 signaling pathway
bta05205 Proteoglycans in cancer
bta05206 MicroRNAs in cancer
bta04014 Ras signaling pathway
bta04015 Rap1 signaling pathway
WikiPathways
WP1052 Id Signaling Pathway
WP982 Hypertrophy Model
WP1065 Endochondral Ossification


Homo sapiens (human) VEGFA NP_003367.4
Canis lupus familiaris (dog) VEGFA NP_001003175.2
Bos taurus (cattle) VEGFA NP_776641.1
Mus musculus (house mouse) Vegfa NP_001020421.2
Rattus norvegicus (Norway rat) Vegfa NP_114024.2
Gallus gallus (chicken) VEGFA NP_990373.1
Danio rerio (zebrafish) vegfab NP_001038320.2

Component

ID Name Evidence
GO:0005576 extracellular region IEA
GO:0005615 extracellular space IDA
GO:0016020 membrane IEA

Function

ID Name Evidence
GO:0005125 cytokine activity IDA
GO:0008083 growth factor activity IDA
GO:0008201 heparin binding IEA
GO:0042803 protein homodimerization activity IDA

Process

ID Name Evidence
GO:0001525 angiogenesis IEA
GO:0001938 positive regulation of endothelial cell proliferation IDA
GO:0007275 multicellular organismal development IEA
GO:0030154 cell differentiation IEA
GO:0051781 positive regulation of cell division IEA
GO:0071456 cellular response to hypoxia IDA

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following VEGFA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VEGFA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OBa45168 XM_005223556 PREDICTED: Bos taurus vascular endothelial growth factor A (VEGFA), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $149.00
OBa01429 NM_174216 Bos taurus vascular endothelial growth factor A (VEGFA), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $149.00

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).


CloneID OBa45168
Accession Version XM_005223556.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 441bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 30-DEC-2014
Organism Bos taurus (cattle)
Product vascular endothelial growth factor A isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104551.1) and transcript sequences (AB450824.1 and GU362063.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 30, 2014 this sequence version replaced gi:529003337. ##RefSeq-Attributes-START## assembly gap :: added 274 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGAACTTTC TGCTCTCTTG GGTACATTGG AGCCTTGCCT TGCTGCTCTA CCTTCACCAT 
GCCAAGTGGT CCCAGGCTGC ACCCATGGCA GAAGGAGGGC AGAAACCCCA CGAAGTGGTG
AAGTTCATGG ATGTCTACCA GCGCAGCTTC TGCCGTCCCA TCGAGACCCT GGTGGACATC
TTCCAGGAGT ACCCAGATGA GATTGAGTTC ATTTTCAAGC CGTCCTGTGT GCCCCTGATG
CGGTGCGGGG GCTGCTGTAA TGACGAAAGT CTGGAGTGTG TGCCCACTGA GGAGTTCAAC
ATCACCATGC AGATTATGCG GATCAAACCT CACCAAAGCC AGCACATAGG AGAGATGAGC
TTCCTACAGC ATAACAAATG TGAATGCAGA CCAAAGAAAG ATAAAGCAAG GCAAGAAAAA
TGTGACAAGC CGAGGCGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_005223613.2
CDS1..441
Misc Feature(1)145..396(+)
Misc Feature(2)145..327(+)
Misc Feature(3)151..387(+)
Misc Feature(4)226..255(+)
Translation
Position Chain Variation Link

Target ORF information:

RefSeq Version XM_005223556
Organism Bos taurus (cattle)
Definition PREDICTED: Bos taurus vascular endothelial growth factor A (VEGFA), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005223556

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGAACTTTC TGCTCTCTTG GGTACATTGG AGCCTTGCCT TGCTGCTCTA CCTTCACCAT 
GCCAAGTGGT CCCAGGCTGC ACCCATGGCA GAAGGAGGGC AGAAACCCCA CGAAGTGGTG
AAGTTCATGG ATGTCTACCA GCGCAGCTTC TGCCGTCCCA TCGAGACCCT GGTGGACATC
TTCCAGGAGT ACCCAGATGA GATTGAGTTC ATTTTCAAGC CGTCCTGTGT GCCCCTGATG
CGGTGCGGGG GCTGCTGTAA TGACGAAAGT CTGGAGTGTG TGCCCACTGA GGAGTTCAAC
ATCACCATGC AGATTATGCG GATCAAACCT CACCAAAGCC AGCACATAGG AGAGATGAGC
TTCCTACAGC ATAACAAATG TGAATGCAGA CCAAAGAAAG ATAAAGCAAG GCAAGAAAAA
TGTGACAAGC CGAGGCGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OBa01429
Accession Version NM_174216.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 573bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 01-JAN-2015
Organism Bos taurus (cattle)
Product vascular endothelial growth factor A precursor
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from M32976.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M32976.1 [ECO:0000332] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGAACTTTC TGCTCTCTTG GGTACATTGG AGCCTTGCCT TGCTGCTCTA CCTTCACCAT 
GCCAAGTGGT CCCAGGCTGC ACCCATGGCA GAAGGAGGGC AGAAACCCCA CGAAGTGGTG
AAGTTCATGG ATGTCTACCA GCGCAGCTTC TGCCGTCCCA TCGAGACCCT GGTGGACATC
TTCCAGGAGT ACCCAGATGA GATTGAGTTC ATTTTCAAGC CGTCCTGTGT GCCCCTGATG
CGGTGCGGGG GCTGCTGTAA TGACGAAAGT CTGGAGTGTG TGCCCACTGA GGAGTTCAAC
ATCACCATGC AGATTATGCG GATCAAACCT CACCAAAGCC AGCACATAGG AGAGATGAGC
TTCCTACAGC ATAACAAATG TGAATGCAGA CCAAAGAAAG ATAAAGCAAG GCAAGAAAAT
CCCTGTGGGC CTTGCTCAGA GCGGAGAAAG CATTTGTTTG TACAAGATCC GCAGACGTGT
AAATGTTCCT GCAAAAACAC AGACTCGCGT TGCAAGGCGA GGCAGCTTGA GTTAAACGAA
CGTACTTGCA GATGTGACAA GCCGAGGCGG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_776641.1
CDS546..1118
Misc Feature(1)690..941(+)
Misc Feature(2)690..872(+)
Misc Feature(3)696..932(+)
Misc Feature(4)771..800(+)
Misc Feature(5)951..1115(+)
Translation
Position Chain Variation Link
76 76 g, t dbSNP:135279522
740 740 a, g dbSNP:110750917
773 773 c, t dbSNP:109288296

Target ORF information:

RefSeq Version NM_174216
Organism Bos taurus (cattle)
Definition Bos taurus vascular endothelial growth factor A (VEGFA), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_174216

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGAACTTTC TGCTCTCTTG GGTACATTGG AGCCTTGCCT TGCTGCTCTA CCTTCACCAT 
GCCAAGTGGT CCCAGGCTGC ACCCATGGCA GAAGGAGGGC AGAAACCCCA CGAAGTGGTG
AAGTTCATGG ATGTCTACCA GCGCAGCTTC TGCCGTCCCA TCGAGACCCT GGTGGACATC
TTCCAGGAGT ACCCAGATGA GATTGAGTTC ATTTTCAAGC CGTCCTGTGT GCCCCTGATG
CGGTGCGGGG GCTGCTGTAA TGACGAAAGT CTGGAGTGTG TGCCCACTGA GGAGTTCAAC
ATCACCATGC AGATTATGCG GATCAAACCT CACCAAAGCC AGCACATAGG AGAGATGAGC
TTCCTACAGC ATAACAAATG TGAATGCAGA CCAAAGAAAG ATAAAGCAAG GCAAGAAAAT
CCCTGTGGGC CTTGCTCAGA GCGGAGAAAG CATTTGTTTG TACAAGATCC GCAGACGTGT
AAATGTTCCT GCAAAAACAC AGACTCGCGT TGCAAGGCGA GGCAGCTTGA GTTAAACGAA
CGTACTTGCA GATGTGACAA GCCGAGGCGG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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