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ntrk1 cDNA ORF clone, Danio rerio (zebrafish)

Gene Symbol ntrk1
Entrez Gene ID 30546
Full Name neurotrophic tyrosine kinase, receptor, type 1
Synonyms trk, trka
General protein information
Preferred Names
high affinity nerve growth factor receptor
Names
high affinity nerve growth factor receptor
tyrosine kinase receptor A
Gene Type protein-coding
Organism Danio rerio (zebrafish)
Summary lac of sum

mRNA and Protein(s)

mRNA Protein Name
NM_001301356 NP_001288285 high affinity nerve growth factor receptor precursor

KEGG
dre04010 MAPK signaling pathway
dre04210 Apoptosis
dre04144 Endocytosis
WikiPathways
WP1337 MAPK signaling pathway


Homo sapiens (human) NTRK1 NP_002520.2
Pan troglodytes (chimpanzee) NTRK1 XP_003308563.1
Macaca mulatta (Rhesus monkey) NTRK1 XP_001114243.2
Canis lupus familiaris (dog) NTRK1 XP_851619.3
Bos taurus (cattle) NTRK1 XP_002686012.2
Mus musculus (house mouse) Ntrk1 NP_001028296.1
Rattus norvegicus (Norway rat) Ntrk1 NP_067600.1
Gallus gallus (chicken) NTRK1 NP_990709.1
Danio rerio (zebrafish) ntrk1 XP_697246.5
Xenopus (Silurana) tropicalis (western clawed frog) ntrk1 XP_002939035.1

Component

ID Name Evidence
GO:0005887 integral to plasma membrane IEA
GO:0016020 membrane IEA
GO:0016021 integral to membrane IEA

Function

ID Name Evidence
GO:0000166 nucleotide binding IEA
GO:0004672 protein kinase activity IEA
GO:0004713 protein tyrosine kinase activity IEA
GO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
GO:0004872 receptor activity IEA
GO:0005030 neurotrophin receptor activity IEA
GO:0005524 ATP binding IEA
GO:0016301 kinase activity IEA
GO:0016740 transferase activity IEA
GO:0016772 transferase activity, transferring phosphorus-containing groups IEA

Process

ID Name Evidence
GO:0006468 protein phosphorylation IEA
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
GO:0016310 phosphorylation IEA

Related articles in PubMed

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ntrk1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ntrk1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
ODa21930 NM_001301356 Danio rerio neurotrophic tyrosine kinase, receptor, type 1 (ntrk1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $426.30
$609.00

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID ODa21930
Clone ID Related Accession (Same CDS sequence) NM_001301356
Accession Version NM_001301356.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2394bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 23-OCT-2014
Organism Danio rerio (zebrafish)
Product high affinity nerve growth factor receptor precursor
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR933818.11. On Aug 12, 2014 this sequence version replaced gi:528504972. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCTGACC ATAGGGTGGC CCCGGTTGTG GGTTTTCTCC TTTTTTTGGT TGCACCGGTC 
TGGAGCGGAT GCCCAAGCGC ATGCCGCTGC TCCTTCGCTA TGCTACAATG CCTGGAGTCA
GATGGCATCA CCAGCATCCC GGCGCTGGCA GCGCAGGAGA GTGAAAACGT CACTGAAATC
TACATAGAGA GTCAACCCAA CCTGGAGAAC ATCACAGATG TAGACCTCGC CAACTACAGA
GAACTGAAGA ATCTGACGAT CACAGATTGT GGGTTGGTGT ACATCTCTGA AAATGCCTTT
CAGCATAACT TCAAGCTGCA GTATGTAAAC CTGGCCTCTA ATGCACTGAC GCACATCAGT
TGGAGGGTGT TCCAATCTGT GACTCTATTG AGTCTGATTT TGAGGGACAA TCTGCTCACC
TGCTCGTGTG ACATTTACTG GCTTCAGCAG TGGCACAGAA AAAGACTAAA CGAAATTGAT
TCTCAGCAAA ATTGCATTTA CAATGGCAGC CAGATTCCGC TGGATTCATT CGAAATGGAT
AACTGCAGTG TTCCTGAGGT CATGATTGAC CCACCGACAG TGACCACTCA AGAAGGTGGA
AATTTGACAT TTACCTGCAG AGTGACTGGA GTTCCCACAC CGACGATCCA CTGGAGAACT
GAGCAGCTTC GGTCCAGCTG GACCCTGGAG CAAGGAATCT GGGGATCAAC CCTGGAGGTG
GTTCTGCACA TGAGAAATGT GTCTTCTGCT GACAACCTGC ACAACCTCAC CTGTGAAGCG
GAGAATCGCG CTGGAATGGG AGATGCTGTG GTGCAGCTGG ACATTGAATT TCCAGTGCGG
ATCATATATC TCAAGAACCC AGAATCTCAA CATCACTGGT GTTTCCCGTT CGCCGTAGAC
AGCAATCCTC CCGCCAGCAT CAAATGGCTG TACAACAACA TGCCTCTCAC TGAGACCCGC
TATGCCTACA CTGAACTCAT CAGAGACGTG TACGACGGCT CACAGCAACA CGGCTGTCTG
TTCCTTAACA AACCCACTCA TCTCAACAAC GGCAACTACA CAATCATCGT GAAGAACAAA
CTGGGCAGAG ACCAGAGAAC AGTCCGAGCC AAGTTCATGG ACAATCCTTT TGATCCCTCT
GACCCGGAGG GCATCATCCC TGTGCTCAAT GACGACCCAA CAGCTCCCAC TAACCAATCA
ACGGAGACGG AGAAAATAGA GAGCAGAGTG TTTGGGGTGT CAGTAGCTGT GGGCCTCGCT
GTGTTTGCGT GCACATTTCT GCTCATCATG GTTGTTGTCA TTAATAAATG TGGACAGCAC
TCCAAGTTTG GCATCCACCG TTCATCAGTT CTGGGCACCG AGGATGATCT GGCAGTGTCT
CTCCGCTTCA TGAACTTCGG TGCTAGTCCT CCATCTTCAG ATGACGGCAC ACTGGATTCT
GGCTTGTCCA GTTTTGTGGA GAACCCGCAA TATTTCTGTG GCATTATCAA AGATAAAGAC
ATGTGTGTTC AGCACATTAA AAGAAAAGAC ATTGTTTTGA AGTGGGAACT GGGTGAAGGA
GCTTTTGGCA AGGTTTATCT GGCTGAATGT GCCAATCTCT GTCCTGATAC TGACAAGATG
CTGGTTGCTA TCAAGACTTT GAAAATAGCC AATGAGTCCA CCCGGCAGGA CTTCCAGCGC
GAGGCTGAGC TGCTCACGGT GCTTCAGCAC GAACACATTG TGCGCTTCTA CGGTGTGTGC
GCAGACGGAG AACCCCTGGC CATGGTGTTT GAGTACATGC GACACGGAGA CCTCAACCGC
TTTCTAAGGG CTCACGGTCC CGATGCTCGT ATATTAGATG AGATGAAGGT TCCTCCGATG
GGTCAGTTGA CTCTTCCTCA GATGCTCCAC ATTGCCGCTC AGATCGCCTC AGGAATGGTG
TACCTGGCGT CCCTTCATTT TGTCCACAGA GACCTGGCCA CAAGGAACTG TCTAGTGGGA
GAAGGGCTGG TAGTGAAGAT CGGGGACTTT GGGATGTCAA GAGACATTTA CAGTACTGAC
TACTACAGGG TCGGAGGCAG GACGATGCTG CCCATTCGCT GGATGCCACC GGAAAGCATT
ATGTACAGGA AGTTCACCAC AGAGAGTGAC ATCTGGAGCT TCGGAGTCGT TTTGTGGGAA
ATCTTCACCT ATGGCAAACA ACCCTGGTAT CAGCTATCCA ACAGTGAGGC CATTGAGTGC
ATCACGCAGG GCCGAGAGCT GGAGCGGCCT CGCACCTGCC CAAAAGAAGT GCACCTCCTG
ATGCAGGGCT GCTGGCAGAG AGAACCACAG CAAAGGTTGG TCATCAAGGA CATCTACAGT
CGCCTCGTGG CCCTCGTCAA AAACCCACCC GTCTACCTGG ACATCCTGGA GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001288285.1
CDS142..2535
Misc Feature(1)40..42(+)
Misc Feature(2)253..309(+)
Misc Feature(3)310..384(+)
Misc Feature(4)379..558(+)
Misc Feature(5)385..456(+)
Misc Feature(6)457..525(+)
Misc Feature(7)526..564(+)
Misc Feature(8)706..966(+)
Misc Feature(9)712..960(+)
Misc Feature(10)1018..1260(+)
Misc Feature(11)1654..2493(+)
Misc Feature(12)1672..2487(+)
Misc Feature(13)1690..2148(+)
Translation
Position Chain Variation Link

Target ORF information:

RefSeq Version NM_001301356
Organism Danio rerio (zebrafish)
Definition Danio rerio neurotrophic tyrosine kinase, receptor, type 1 (ntrk1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001301356

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCTGACC ATAGGGTGGC CCCGGTTGTG GGTTTTCTCC TTTTTTTGGT TGCACCGGTC 
TGGAGCGGAT GCCCAAGCGC ATGCCGCTGC TCCTTCGCTA TGCTACAATG CCTGGAGTCA
GATGGCATCA CCAGCATCCC GGCGCTGGCA GCGCAGGAGA GTGAAAACGT CACTGAAATC
TACATAGAGA GTCAACCCAA CCTGGAGAAC ATCACAGATG TAGACCTCGC CAACTACAGA
GAACTGAAGA ATCTGACGAT CACAGATTGT GGGTTGGTGT ACATCTCTGA AAATGCCTTT
CAGCATAACT TCAAGCTGCA GTATGTAAAC CTGGCCTCTA ATGCACTGAC GCACATCAGT
TGGAGGGTGT TCCAATCTGT GACTCTATTG AGTCTGATTT TGAGGGACAA TCTGCTCACC
TGCTCGTGTG ACATTTACTG GCTTCAGCAG TGGCACAGAA AAAGACTAAA CGAAATTGAT
TCTCAGCAAA ATTGCATTTA CAATGGCAGC CAGATTCCGC TGGATTCATT CGAAATGGAT
AACTGCAGTG TTCCTGAGGT CATGATTGAC CCACCGACAG TGACCACTCA AGAAGGTGGA
AATTTGACAT TTACCTGCAG AGTGACTGGA GTTCCCACAC CGACGATCCA CTGGAGAACT
GAGCAGCTTC GGTCCAGCTG GACCCTGGAG CAAGGAATCT GGGGATCAAC CCTGGAGGTG
GTTCTGCACA TGAGAAATGT GTCTTCTGCT GACAACCTGC ACAACCTCAC CTGTGAAGCG
GAGAATCGCG CTGGAATGGG AGATGCTGTG GTGCAGCTGG ACATTGAATT TCCAGTGCGG
ATCATATATC TCAAGAACCC AGAATCTCAA CATCACTGGT GTTTCCCGTT CGCCGTAGAC
AGCAATCCTC CCGCCAGCAT CAAATGGCTG TACAACAACA TGCCTCTCAC TGAGACCCGC
TATGCCTACA CTGAACTCAT CAGAGACGTG TACGACGGCT CACAGCAACA CGGCTGTCTG
TTCCTTAACA AACCCACTCA TCTCAACAAC GGCAACTACA CAATCATCGT GAAGAACAAA
CTGGGCAGAG ACCAGAGAAC AGTCCGAGCC AAGTTCATGG ACAATCCTTT TGATCCCTCT
GACCCGGAGG GCATCATCCC TGTGCTCAAT GACGACCCAA CAGCTCCCAC TAACCAATCA
ACGGAGACGG AGAAAATAGA GAGCAGAGTG TTTGGGGTGT CAGTAGCTGT GGGCCTCGCT
GTGTTTGCGT GCACATTTCT GCTCATCATG GTTGTTGTCA TTAATAAATG TGGACAGCAC
TCCAAGTTTG GCATCCACCG TTCATCAGTT CTGGGCACCG AGGATGATCT GGCAGTGTCT
CTCCGCTTCA TGAACTTCGG TGCTAGTCCT CCATCTTCAG ATGACGGCAC ACTGGATTCT
GGCTTGTCCA GTTTTGTGGA GAACCCGCAA TATTTCTGTG GCATTATCAA AGATAAAGAC
ATGTGTGTTC AGCACATTAA AAGAAAAGAC ATTGTTTTGA AGTGGGAACT GGGTGAAGGA
GCTTTTGGCA AGGTTTATCT GGCTGAATGT GCCAATCTCT GTCCTGATAC TGACAAGATG
CTGGTTGCTA TCAAGACTTT GAAAATAGCC AATGAGTCCA CCCGGCAGGA CTTCCAGCGC
GAGGCTGAGC TGCTCACGGT GCTTCAGCAC GAACACATTG TGCGCTTCTA CGGTGTGTGC
GCAGACGGAG AACCCCTGGC CATGGTGTTT GAGTACATGC GACACGGAGA CCTCAACCGC
TTTCTAAGGG CTCACGGTCC CGATGCTCGT ATATTAGATG AGATGAAGGT TCCTCCGATG
GGTCAGTTGA CTCTTCCTCA GATGCTCCAC ATTGCCGCTC AGATCGCCTC AGGAATGGTG
TACCTGGCGT CCCTTCATTT TGTCCACAGA GACCTGGCCA CAAGGAACTG TCTAGTGGGA
GAAGGGCTGG TAGTGAAGAT CGGGGACTTT GGGATGTCAA GAGACATTTA CAGTACTGAC
TACTACAGGG TCGGAGGCAG GACGATGCTG CCCATTCGCT GGATGCCACC GGAAAGCATT
ATGTACAGGA AGTTCACCAC AGAGAGTGAC ATCTGGAGCT TCGGAGTCGT TTTGTGGGAA
ATCTTCACCT ATGGCAAACA ACCCTGGTAT CAGCTATCCA ACAGTGAGGC CATTGAGTGC
ATCACGCAGG GCCGAGAGCT GGAGCGGCCT CGCACCTGCC CAAAAGAAGT GCACCTCCTG
ATGCAGGGCT GCTGGCAGAG AGAACCACAG CAAAGGTTGG TCATCAAGGA CATCTACAGT
CGCCTCGTGG CCCTCGTCAA AAACCCACCC GTCTACCTGG ACATCCTGGA GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

New transgenic reporters identify somatosensory neuron subtypes in larval zebrafish
Dev Neurobiol 73 (2), 152-167 (2013)
Palanca AM, Lee SL, Yee LE, Joe-Wong C, Trinh le A, Hiroyasu E, Husain M, Fraser SE, Pellegrini M and Sagasti A.


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Zebrafish crypt neurons project to a single, identified mediodorsal glomerulus
Sci Rep 3, 2063 (2013)
Ahuja G, Ivandic I, Salturk M, Oka Y, Nadler W and Korsching SI.


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Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons
Development 139 (3), 591-600 (2012)
Pan YA, Choy M, Prober DA and Schier AF.


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Assignment of zebrafish genetic linkage groups to chromosomes
Cytogenet. Genome Res. 114 (2), 155-162 (2006)
Phillips RB, Amores A, Morasch MR, Wilson C and Postlethwait JH.


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The zebrafish gene map defines ancestral vertebrate chromosomes
Genome Res. 15 (9), 1307-1314 (2005)
Woods IG, Wilson C, Friedlander B, Chang P, Reyes DK, Nix R, Kelly PD, Chu F, Postlethwait JH and Talbot WS.


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Hematopoietic gene expression profile in zebrafish kidney marrow
Proc. Natl. Acad. Sci. U.S.A. 101 (46), 16240-16245 (2004)
Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y, Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT and Chen Z.


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Neurotrophin receptors in taste buds of adult zebrafish (Danio rerio)
Neurosci. Lett. 354 (3), 189-192 (2004)
Germana A, Gonzalez-Martinez T, Catania S, Laura R, Cobo J, Ciriaco E and Vega JA.


book

The crypt neurons in the olfactory epithelium of the adult zebrafish express TrkA-like immunoreactivity
Neurosci. Lett. 350 (1), 5-8 (2003)
Catania S, Germana A, Laura R, Gonzalez-Martinez T, Ciriaco E and Vega JA.


 
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