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MRLN cDNA ORF clone, Homo sapiens (human)

Gene Symbol MRLN
Entrez Gene ID 100507027
Full Name myoregulin
Synonyms LINC00948, M1, MLN, MUSER1
Gene Type protein-coding
Organism Homo sapiens (human)
Summary This gene encodes a small peptide that shares structural similarity to the small peptides sarcolipin and phospholamban, which are key regulators of sarcoplasmic reticulum Ca(2+)-ATPases (SERCAs). This protein is thought to have a similar function to these peptides, regulating Ca(2+) reuptake in the sarcoplasmic reticulum by inhibiting the Ca(2+) pump activity of SERCAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2015]. lac of sum
Disorder MIM:

616246


mRNA and Protein(s)

mRNA Protein Name
XM_011539100 XP_011537402 myoregulin isoform X1
NM_001304731 NP_001291660 myoregulin
NM_001304732 NP_001291661 myoregulin

Related articles in PubMed

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MRLN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MRLN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu81121 XM_011539100 PREDICTED: Homo sapiens myoregulin (MRLN), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu81121 NM_001304731 Homo sapiens myoregulin (MRLN), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu81121 NM_001304732 Homo sapiens myoregulin (MRLN), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
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30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu81121
Clone ID Related Accession (Same CDS sequence) NM_001304731 , NM_001304732 , XM_011539100
Accession Version XM_011539100.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 141bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product myoregulin isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_030059.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
ATGACTGGTA AAAACTGGAT ATTAATTTCT ACTACTACTC CCAAAAGTCT AGAAGATGAA 
ATTGTGGGAA GACTTCTAAA AATTTTGTTT GTTATCTTTG TTGACTTAAT TTCTATTATA
TATGTTGTGA TAACTTCTTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011537402.1
CDS254..394
Translation

Target ORF information:

RefSeq Version XM_011539100
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens myoregulin (MRLN), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011539100

ORF Insert Sequence:

1
61
121
ATGACTGGTA AAAACTGGAT ATTAATTTCT ACTACTACTC CCAAAAGTCT AGAAGATGAA 
ATTGTGGGAA GACTTCTAAA AATTTTGTTT GTTATCTTTG TTGACTTAAT TTCTATTATA
TATGTTGTGA TAACTTCTTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu81121
Clone ID Related Accession (Same CDS sequence) NM_001304731 , NM_001304732 , XM_011539100
Accession Version NM_001304731.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 141bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 02-JUN-2015
Organism Homo sapiens (human)
Product myoregulin
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB019391.1 and BG210823.1. On Feb 6, 2015 this sequence version replaced gi:333108229. Transcript Variant: This variant (2) lacks an exon in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AB019391.1, AF086308.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
ATGACTGGTA AAAACTGGAT ATTAATTTCT ACTACTACTC CCAAAAGTCT AGAAGATGAA 
ATTGTGGGAA GACTTCTAAA AATTTTGTTT GTTATCTTTG TTGACTTAAT TTCTATTATA
TATGTTGTGA TAACTTCTTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001291660.1
CDS217..357
Misc Feature(1)106..108(+)
Misc Feature(2)280..342(+)
Exon (1)1..92
Gene:MRLN
Gene Synonym:
Exon (2)93..196
Gene:MRLN
Gene Synonym:
Exon (3)197..427
Gene:MRLN
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001304731
Organism Homo sapiens (human)
Definition Homo sapiens myoregulin (MRLN), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001304731

ORF Insert Sequence:

1
61
121
ATGACTGGTA AAAACTGGAT ATTAATTTCT ACTACTACTC CCAAAAGTCT AGAAGATGAA 
ATTGTGGGAA GACTTCTAAA AATTTTGTTT GTTATCTTTG TTGACTTAAT TTCTATTATA
TATGTTGTGA TAACTTCTTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu81121
Clone ID Related Accession (Same CDS sequence) NM_001304731 , NM_001304732 , XM_011539100
Accession Version NM_001304732.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 141bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 02-JUN-2015
Organism Homo sapiens (human)
Product myoregulin
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB019391.1, BM021470.1 and BG210823.1. On Feb 6, 2015 this sequence version replaced gi:333108237. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BM021470.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2158800 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
ATGACTGGTA AAAACTGGAT ATTAATTTCT ACTACTACTC CCAAAAGTCT AGAAGATGAA 
ATTGTGGGAA GACTTCTAAA AATTTTGTTT GTTATCTTTG TTGACTTAAT TTCTATTATA
TATGTTGTGA TAACTTCTTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001291661.1
CDS339..479
Misc Feature(1)228..230(+)
Misc Feature(2)402..464(+)
Exon (1)1..92
Gene:MRLN
Gene Synonym:
Exon (2)93..214
Gene:MRLN
Gene Synonym:
Exon (3)215..318
Gene:MRLN
Gene Synonym:
Exon (4)319..549
Gene:MRLN
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001304732
Organism Homo sapiens (human)
Definition Homo sapiens myoregulin (MRLN), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001304732

ORF Insert Sequence:

1
61
121
ATGACTGGTA AAAACTGGAT ATTAATTTCT ACTACTACTC CCAAAAGTCT AGAAGATGAA 
ATTGTGGGAA GACTTCTAAA AATTTTGTTT GTTATCTTTG TTGACTTAAT TTCTATTATA
TATGTTGTGA TAACTTCTTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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