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EBI3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol EBI3
Entrez Gene ID 10148
Full Name Epstein-Barr virus induced 3
Synonyms IL-27B, IL27B
General protein information
Preferred Names
interleukin-27 subunit beta
Names
interleukin-27 subunit beta
IL27 subunit
IL35 subunit
cytokine receptor
IL-27 subunit beta
EBV-induced gene 3 protein
Epstein-Barr virus induced gene 3
epstein-Barr virus-induced gene 3 protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.3

Summary This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008]. lac of sum
Disorder MIM:

605816


mRNA and Protein(s)

mRNA Protein Name
XM_011527619 XP_011525921 interleukin-27 subunit beta isoform X1
NM_005755 NP_005746 interleukin-27 subunit beta precursor



Homo sapiens (human) EBI3 NP_005746.2
Pan troglodytes (chimpanzee) EBI3 XP_001138182.1
Canis lupus familiaris (dog) EBI3 XP_542161.3
Bos taurus (cattle) EBI3 NP_001093835.1
Mus musculus (house mouse) Ebi3 NP_056581.1
Rattus norvegicus (Norway rat) Ebi3 NP_001102891.1
Danio rerio (zebrafish) ebi3 NP_001106980.1
Xenopus (Silurana) tropicalis (western clawed frog) ebi3 XP_002934057.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following EBI3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EBI3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17365
XM_011527619 PREDICTED: Homo sapiens Epstein-Barr virus induced 3 (EBI3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu17365
NM_005755 Homo sapiens Epstein-Barr virus induced 3 (EBI3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu17365
Clone ID Related Accession (Same CDS sequence) NM_005755 , XM_011527619
Accession Version XM_011527619.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 690bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product interleukin-27 subunit beta isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011295.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011525921.1
CDS152..841
Misc Feature(1)290..496(+)
Misc Feature(2)536..823(+)
Misc Feature(3)536..787(+)
Misc Feature(4)788..805(+)
Translation

Target ORF information:

RefSeq Version XM_011527619
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens Epstein-Barr virus induced 3 (EBI3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011527619

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17365
Clone ID Related Accession (Same CDS sequence) NM_005755 , XM_011527619
Accession Version NM_005755.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 690bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product interleukin-27 subunit beta precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L08187.1. On Jun 29, 2001 this sequence version replaced gi:5031678. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015364.1, L08187.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
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361
421
481
541
601
661
ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_005746.2
CDS9..698
Misc Feature(1)147..353(+)
Misc Feature(2)393..680(+)
Misc Feature(3)393..644(+)
Misc Feature(4)645..662(+)
Exon (1)1..75
Gene:EBI3
Gene Synonym:
Exon (2)76..208
Gene:EBI3
Gene Synonym:
Exon (3)209..387
Gene:EBI3
Gene Synonym:
Exon (4)388..545
Gene:EBI3
Gene Synonym:
Exon (5)546..1138
Gene:EBI3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_005755
Organism Homo sapiens (human)
Definition Homo sapiens Epstein-Barr virus induced 3 (EBI3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_005755

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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