The following CDK3 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDK3 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 918bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||cyclin-dependent kinase 3
||VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DB455174.1, X66357.1, BU784937.1, AU146328.1 and BX098771.1.
On Jan 9, 2008 this sequence version replaced gi:4557438.
Summary: This gene encodes a member of the cyclin-dependent protein
kinase family. The protein promotes entry into S phase, in part by
activating members of the E2F family of transcription factors. The
protein also associates with cyclin C and phosphorylates the
retinoblastoma 1 protein to promote exit from G0. [provided by
RefSeq, Jul 2008].
Sequence Note: A downstream translational start codon is selected
for this RefSeq based on its better conservation in mammalian
species and on a strong Kozak signal. An upstream in-frame start
codon is also present but has a weaker Kozak signal and is poorly
conserved. Use of the upstream start codon would result in a
protein that is 20 aa longer at the N-terminus. Leaky scanning by
ribosomes may allow translation initiation at the downstream start
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
is not conserved
CDS exon combination :: AK097104.1, X66357.1 [ECO:0000331]
RNAseq introns :: single sample supports all introns
SAMEA1968968, SAMEA2148093 [ECO:0000348]
COMPLETENESS: complete on the 3' end.