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CDK5 cyclin-dependent kinase 5 [Homo sapiens (human)]

Gene Symbol CDK5
Entrez Gene ID 1020
Full Name cyclin-dependent kinase 5
Synonyms LIS7, PSSALRE
General protein information
Preferred Names
cyclin-dependent kinase 5
Names
cyclin-dependent kinase 5
TPKII catalytic subunit
protein kinase CDK5 splicing
cell division protein kinase 5
serine/threonine-protein kinase PSSALRE
tau protein kinase II catalytic subunit
NP_001157882.1
NP_004926.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7q36

Summary This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]. lac of sum
Disorder MIM:

123831

Disorder Html:
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu12869 NM_001164410 Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00
OHu12814 NM_004935 Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu12869D
Sequence Information ORF Nucleotide Sequence (Length: 783bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 23-MAY-2015
Organism Homo sapiens (human)
Product cyclin-dependent-like kinase 5 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB487008.1, AC010973.7, AK026533.1, DQ411039.1 and CA429180.1. On Jan 6, 2015 this sequence version replaced gi:256542305. Summary: This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]. Transcript Variant: This variant (2), also known as CDK5-SV, omits an in-frame coding exon compared to variant 1 resulting in a shorter predicted protein (isoform 2). Expression of this transcript was described by Li et al. (2009; PubMed ID 19693690). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ411039.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCAGAAAT ACGAGAAACT GGAAAAGATT GGGGAAGGCA CCTACGGAAC TGTGTTCAAG 
GCCAAAAACC GGGAGACTCA TGAGATCGTG GCTCTGAAAC GGGTGAGGCT GGATGACGAT
GATGAGGGTG TGCCGAGTTC CGCCCTCCGG GAGATCTGCC TACTCAAGGA GCTGAAGCAC
AAGAACATCG TCAGGCTTCA TGACGTCCTG CACAGCGACA AGAAGCTGAC TTTGGTTTTT
GAATTCTGTG ACCAGGACCT GAAGAAGTAT TTTGACAGTT GCAATGGTGA CCTCGATCCT
GAGATTGTAA AGAATGGGGA GCTGAAATTG GCTGATTTTG GCCTGGCTCG AGCCTTTGGG
ATTCCCGTCC GCTGTTACTC AGCTGAGGTG GTCACACTGT GGTACCGCCC ACCGGATGTC
CTCTTTGGGG CCAAGCTGTA CTCCACGTCC ATCGACATGT GGTCAGCCGG CTGCATCTTT
GCAGAGCTGG CCAATGCTGG GCGGCCTCTT TTTCCCGGCA ATGATGTCGA TGACCAGTTG
AAGAGGATCT TCCGACTGCT GGGGACGCCC ACCGAGGAGC AGTGGCCCTC TATGACCAAG
CTGCCAGACT ATAAGCCCTA TCCGATGTAC CCGGCCACAA CATCCCTGGT GAACGTCGTG
CCCAAACTCA ATGCCACAGG GAGGGATCTG CTGCAGAACC TTCTGAAGTG TAACCCTGTC
CAGCGTATCT CAGCAGAAGA GGCCCTGCAG CACCCCTACT TCTCCGACTT CTGTCCGCCC
TAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001157882.1
CDS118..900
Misc Feature(1)79..81(+)
Misc Feature(2)118..885(+)
Misc Feature(3)124..879(+)
Misc Feature(4)145..453(+)
Exon (1)1..154
Gene:CDK5
Gene Synonym:
Exon (2)155..243
Gene:CDK5
Gene Synonym:
Exon (3)244..311
Gene:CDK5
Gene Synonym:
Exon (4)312..372
Gene:CDK5
Gene Synonym:
Exon (5)373..429
Gene:CDK5
Gene Synonym:
Exon (6)430..504
Gene:CDK5
Gene Synonym:
Exon (7)505..601
Gene:CDK5
Gene Synonym:
Exon (8)602..671
Gene:CDK5
Gene Synonym:
Exon (9)672..732
Gene:CDK5
Gene Synonym:
Exon (10)733..813
Gene:CDK5
Gene Synonym:
Exon (11)814..1097
Gene:CDK5
Gene Synonym:
Translation
Position Chain Variation Link
45 45 g, t dbSNP:571097139
52 52 g, t dbSNP:548065567
55 55 c, t dbSNP:534298842
66 66 g, t dbSNP:368436761
69 69 c, g dbSNP:753303705
71 71 c, g dbSNP:765603464
74 74 -, ag dbSNP:767129293
74 74 a, t dbSNP:759691479
75 75 a, g dbSNP:753931084
85 85 c, g dbSNP:766731629
86 86 c, g dbSNP:761027432
90 90 a, g dbSNP:773537135
92 92 a, c, g dbSNP:527916400
96 96 a, g dbSNP:775513156
99 99 a, g, t dbSNP:568654766
100 100 a, g, t dbSNP:770392459
104 104 c, t dbSNP:548765893
107 107 c, g dbSNP:375106537
108 108 a, g dbSNP:370700495
112 112 g, t dbSNP:758802677
113 113 c, t dbSNP:752935256
117 117 a, g dbSNP:547658726
135 135 a, g dbSNP:779507948
140 140 a, g dbSNP:755494715
141 141 a, c dbSNP:754375531
187 187 -, g dbSNP:35475821
189 189 c, g dbSNP:751770862
192 192 a, g dbSNP:765078681
194 194 c, g dbSNP:759312847
195 195 c, t dbSNP:776562781
202 202 a, g dbSNP:200087231
204 204 c, g dbSNP:766236667
237 237 c, t dbSNP:760261892
252 252 a, g dbSNP:766324720
258 258 c, t dbSNP:760579593
265 265 c, t dbSNP:377383594
267 267 g, t dbSNP:767003240
278 278 a, t dbSNP:761373694
305 305 c, t dbSNP:774164033
322 322 a, g dbSNP:762731440
324 324 a, c dbSNP:775274881
333 333 c, t dbSNP:531146226
342 342 a, g dbSNP:759883551
347 347 a, c dbSNP:777007468
351 351 c, g dbSNP:771429450
363 363 c, t dbSNP:369446117
370 370 c, g dbSNP:777878897
384 384 a, g dbSNP:779010975
393 393 c, t dbSNP:754863632
422 422 c, t dbSNP:368886325
427 427 a, g dbSNP:200729612
432 432 c, t dbSNP:755717863
435 435 g, t dbSNP:567702898
439 439 a, c dbSNP:750272338
471 471 c, t dbSNP:1057766
473 473 c, t dbSNP:781580336
474 474 c, t dbSNP:757562417
483 483 c, g, t dbSNP:764437263
484 484 a, g dbSNP:763122603
528 528 a, g dbSNP:765479272
530 530 c, t dbSNP:759675039
531 531 a, g dbSNP:754127997
564 564 a, g dbSNP:368677466
565 565 g, t dbSNP:775219441
570 570 c, t dbSNP:773970698
571 571 a, g dbSNP:763930713
575 575 c, t dbSNP:572198432
585 585 c, t dbSNP:762841652
588 588 c, t dbSNP:775406194
591 591 c, t dbSNP:769355512
615 615 g, t dbSNP:763866365
618 618 a, g dbSNP:762042930
631 631 a, c dbSNP:762727632
633 633 c, t dbSNP:376139702
636 636 c, t dbSNP:375689583
645 645 c, t dbSNP:759067345
648 648 c, t dbSNP:772428305
669 669 c, g dbSNP:776051072
671 671 a, g dbSNP:770442459
683 683 c, t dbSNP:369223059
684 684 a, g dbSNP:760173955
690 690 c, g, t dbSNP:369291948
691 691 a, g dbSNP:762292489
696 696 a, g, t dbSNP:35186917
704 704 c, t dbSNP:374928837
709 709 a, g dbSNP:749880275
717 717 a, g dbSNP:780601142
732 732 g, t dbSNP:757027718
740 740 c, t dbSNP:781286909
741 741 a, g, t dbSNP:62490285
749 749 c, t dbSNP:777914064
750 750 a, g dbSNP:754772887
751 751 a, g dbSNP:753629423
755 755 c, t dbSNP:779879090
756 756 a, g dbSNP:756128106
758 758 c, t dbSNP:750298451
766 766 c, g dbSNP:767206570
771 771 c, t dbSNP:756816841
774 774 c, g, t dbSNP:763777369
800 800 a, g dbSNP:113702561
801 801 a, g dbSNP:763244697
803 803 a, t dbSNP:775968819
827 827 a, g dbSNP:745860943
841 841 c, t dbSNP:781221793
842 842 a, g dbSNP:548208867
848 848 c, t dbSNP:751078477
855 855 a, t dbSNP:202114425
860 860 c, t dbSNP:758106701
863 863 c, t dbSNP:200333664
864 864 a, c, g dbSNP:11541602
872 872 a, c, g dbSNP:553172337
882 882 c, t dbSNP:763946310
883 883 a, g dbSNP:777125495
893 893 c, t dbSNP:766831959
894 894 a, g, t dbSNP:773329997
897 897 c, g dbSNP:772015673
905 905 c, t dbSNP:2069460
906 906 a, c, g dbSNP:371735422
914 914 a, c, t dbSNP:368178302
915 915 a, g dbSNP:79627316
929 929 a, g dbSNP:746908389
947 947 a, c dbSNP:777405337
950 950 c, t dbSNP:775198732
976 976 a, g dbSNP:554235263
986 986 c, t dbSNP:35051446
993 993 c, g dbSNP:575163799
1015 1015 c, t dbSNP:2069461
1016 1016 a, g dbSNP:9278
1018 1018 a, g dbSNP:116863165
1021 1021 g, t dbSNP:566748363
1035 1035 c, t dbSNP:144982250
1050 1050 c, t dbSNP:753001382
1081 1081 g, t dbSNP:529902552

Target ORF information:

RefSeq Version NM_001164410
Organism Homo sapiens (human)
Definition Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001164410

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCAGAAAT ACGAGAAACT GGAAAAGATT GGGGAAGGCA CCTACGGAAC TGTGTTCAAG 
GCCAAAAACC GGGAGACTCA TGAGATCGTG GCTCTGAAAC GGGTGAGGCT GGATGACGAT
GATGAGGGTG TGCCGAGTTC CGCCCTCCGG GAGATCTGCC TACTCAAGGA GCTGAAGCAC
AAGAACATCG TCAGGCTTCA TGACGTCCTG CACAGCGACA AGAAGCTGAC TTTGGTTTTT
GAATTCTGTG ACCAGGACCT GAAGAAGTAT TTTGACAGTT GCAATGGTGA CCTCGATCCT
GAGATTGTAA AGAATGGGGA GCTGAAATTG GCTGATTTTG GCCTGGCTCG AGCCTTTGGG
ATTCCCGTCC GCTGTTACTC AGCTGAGGTG GTCACACTGT GGTACCGCCC ACCGGATGTC
CTCTTTGGGG CCAAGCTGTA CTCCACGTCC ATCGACATGT GGTCAGCCGG CTGCATCTTT
GCAGAGCTGG CCAATGCTGG GCGGCCTCTT TTTCCCGGCA ATGATGTCGA TGACCAGTTG
AAGAGGATCT TCCGACTGCT GGGGACGCCC ACCGAGGAGC AGTGGCCCTC TATGACCAAG
CTGCCAGACT ATAAGCCCTA TCCGATGTAC CCGGCCACAA CATCCCTGGT GAACGTCGTG
CCCAAACTCA ATGCCACAGG GAGGGATCTG CTGCAGAACC TTCTGAAGTG TAACCCTGTC
CAGCGTATCT CAGCAGAAGA GGCCCTGCAG CACCCCTACT TCTCCGACTT CTGTCCGCCC
TAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu12814D
Sequence Information ORF Nucleotide Sequence (Length: 879bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 27-MAY-2015
Organism Homo sapiens (human)
Product cyclin-dependent-like kinase 5 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB487008.1, AC010973.7, BP309068.1, BC005115.1, AK026533.1 and CA429180.1. This sequence is a reference standard in the RefSeqGene project. On Aug 26, 2009 this sequence version replaced gi:38454327. Summary: This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK026533.1, BC005115.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGCAGAAAT ACGAGAAACT GGAAAAGATT GGGGAAGGCA CCTACGGAAC TGTGTTCAAG 
GCCAAAAACC GGGAGACTCA TGAGATCGTG GCTCTGAAAC GGGTGAGGCT GGATGACGAT
GATGAGGGTG TGCCGAGTTC CGCCCTCCGG GAGATCTGCC TACTCAAGGA GCTGAAGCAC
AAGAACATCG TCAGGCTTCA TGACGTCCTG CACAGCGACA AGAAGCTGAC TTTGGTTTTT
GAATTCTGTG ACCAGGACCT GAAGAAGTAT TTTGACAGTT GCAATGGTGA CCTCGATCCT
GAGATTGTAA AGTCATTCCT CTTCCAGCTA CTAAAAGGGC TGGGATTCTG TCATAGCCGC
AATGTGCTAC ACAGGGACCT GAAGCCCCAG AACCTGCTAA TAAACAGGAA TGGGGAGCTG
AAATTGGCTG ATTTTGGCCT GGCTCGAGCC TTTGGGATTC CCGTCCGCTG TTACTCAGCT
GAGGTGGTCA CACTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCCAA TGCTGGGCGG
CCTCTTTTTC CCGGCAATGA TGTCGATGAC CAGTTGAAGA GGATCTTCCG ACTGCTGGGG
ACGCCCACCG AGGAGCAGTG GCCCTCTATG ACCAAGCTGC CAGACTATAA GCCCTATCCG
ATGTACCCGG CCACAACATC CCTGGTGAAC GTCGTGCCCA AACTCAATGC CACAGGGAGG
GATCTGCTGC AGAACCTTCT GAAGTGTAAC CCTGTCCAGC GTATCTCAGC AGAAGAGGCC
CTGCAGCACC CCTACTTCTC CGACTTCTGT CCGCCCTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_004926.1
CDS118..996
Misc Feature(1)79..81(+)
Misc Feature(2)118..981(+)
Misc Feature(3)124..975(+)
Misc Feature(4)145..735(+)
Misc Feature(5)145..549(+)
Misc Feature(6)160..162(+)
Misc Feature(7)160..162(+)
Misc Feature(8)160..162(+)
Misc Feature(9)226..594(+)
Misc Feature(10)265..732(+)
Misc Feature(11)283..285(+)
Misc Feature(12)331..333(+)
Misc Feature(13)544..615(+)
Misc Feature(14)592..594(+)
Misc Feature(15)592..594(+)
Exon (1)1..154
Gene:CDK5
Gene Synonym:
Exon (2)155..243
Gene:CDK5
Gene Synonym:
Exon (3)244..311
Gene:CDK5
Gene Synonym:
Exon (4)312..372
Gene:CDK5
Gene Synonym:
Exon (5)373..429
Gene:CDK5
Gene Synonym:
Exon (6)430..525
Gene:CDK5
Gene Synonym:
Exon (7)526..600
Gene:CDK5
Gene Synonym:
Exon (8)601..697
Gene:CDK5
Gene Synonym:
Exon (9)698..767
Gene:CDK5
Gene Synonym:
Exon (10)768..828
Gene:CDK5
Gene Synonym:
Exon (11)829..909
Gene:CDK5
Gene Synonym:
Exon (12)910..1193
Gene:CDK5
Gene Synonym:
Translation
Position Chain Variation Link
45 45 g, t dbSNP:571097139
52 52 g, t dbSNP:548065567
55 55 c, t dbSNP:534298842
66 66 g, t dbSNP:368436761
69 69 c, g dbSNP:753303705
71 71 c, g dbSNP:765603464
74 74 -, ag dbSNP:767129293
74 74 a, t dbSNP:759691479
75 75 a, g dbSNP:753931084
85 85 c, g dbSNP:766731629
86 86 c, g dbSNP:761027432
90 90 a, g dbSNP:773537135
92 92 a, c, g dbSNP:527916400
96 96 a, g dbSNP:775513156
99 99 a, g, t dbSNP:568654766
100 100 a, g, t dbSNP:770392459
104 104 c, t dbSNP:548765893
107 107 c, g dbSNP:375106537
108 108 a, g dbSNP:370700495
112 112 g, t dbSNP:758802677
113 113 c, t dbSNP:752935256
117 117 a, g dbSNP:547658726
135 135 a, g dbSNP:779507948
140 140 a, g dbSNP:755494715
141 141 a, c dbSNP:754375531
187 187 -, g dbSNP:35475821
189 189 c, g dbSNP:751770862
192 192 a, g dbSNP:765078681
194 194 c, g dbSNP:759312847
195 195 c, t dbSNP:776562781
202 202 a, g dbSNP:200087231
204 204 c, g dbSNP:766236667
237 237 c, t dbSNP:760261892
252 252 a, g dbSNP:766324720
258 258 c, t dbSNP:760579593
265 265 c, t dbSNP:377383594
267 267 g, t dbSNP:767003240
278 278 a, t dbSNP:761373694
305 305 c, t dbSNP:774164033
322 322 a, g dbSNP:762731440
324 324 a, c dbSNP:775274881
333 333 c, t dbSNP:531146226
342 342 a, g dbSNP:759883551
347 347 a, c dbSNP:777007468
351 351 c, g dbSNP:771429450
363 363 c, t dbSNP:369446117
370 370 c, g dbSNP:777878897
384 384 a, g dbSNP:779010975
393 393 c, t dbSNP:754863632
422 422 c, t dbSNP:368886325
427 427 a, g dbSNP:200729612
433 433 c, t dbSNP:774444285
456 456 a, g dbSNP:768598460
471 471 c, t dbSNP:749567698
475 475 c, t dbSNP:373178311
476 476 a, g dbSNP:770858106
479 479 a, g dbSNP:746730482
504 504 c, t dbSNP:777882765
510 510 c, t dbSNP:370113778
528 528 c, t dbSNP:755717863
531 531 g, t dbSNP:567702898
535 535 a, c dbSNP:750272338
567 567 c, t dbSNP:1057766
569 569 c, t dbSNP:781580336
570 570 c, t dbSNP:757562417
579 579 c, g, t dbSNP:764437263
580 580 a, g dbSNP:763122603
624 624 a, g dbSNP:765479272
626 626 c, t dbSNP:759675039
627 627 a, g dbSNP:754127997
660 660 a, g dbSNP:368677466
661 661 g, t dbSNP:775219441
666 666 c, t dbSNP:773970698
667 667 a, g dbSNP:763930713
671 671 c, t dbSNP:572198432
681 681 c, t dbSNP:762841652
684 684 c, t dbSNP:775406194
687 687 c, t dbSNP:769355512
711 711 g, t dbSNP:763866365
714 714 a, g dbSNP:762042930
727 727 a, c dbSNP:762727632
729 729 c, t dbSNP:376139702
732 732 c, t dbSNP:375689583
741 741 c, t dbSNP:759067345
744 744 c, t dbSNP:772428305
765 765 c, g dbSNP:776051072
767 767 a, g dbSNP:770442459
779 779 c, t dbSNP:369223059
780 780 a, g dbSNP:760173955
786 786 c, g, t dbSNP:369291948
787 787 a, g dbSNP:762292489
792 792 a, g, t dbSNP:35186917
800 800 c, t dbSNP:374928837
805 805 a, g dbSNP:749880275
813 813 a, g dbSNP:780601142
828 828 g, t dbSNP:757027718
836 836 c, t dbSNP:781286909
837 837 a, g, t dbSNP:62490285
845 845 c, t dbSNP:777914064
846 846 a, g dbSNP:754772887
847 847 a, g dbSNP:753629423
851 851 c, t dbSNP:779879090
852 852 a, g dbSNP:756128106
854 854 c, t dbSNP:750298451
862 862 c, g dbSNP:767206570
867 867 c, t dbSNP:756816841
870 870 c, g, t dbSNP:763777369
896 896 a, g dbSNP:113702561
897 897 a, g dbSNP:763244697
899 899 a, t dbSNP:775968819
923 923 a, g dbSNP:745860943
937 937 c, t dbSNP:781221793
938 938 a, g dbSNP:548208867
944 944 c, t dbSNP:751078477
951 951 a, t dbSNP:202114425
956 956 c, t dbSNP:758106701
959 959 c, t dbSNP:200333664
960 960 a, c, g dbSNP:11541602
968 968 a, c, g dbSNP:553172337
978 978 c, t dbSNP:763946310
979 979 a, g dbSNP:777125495
989 989 c, t dbSNP:766831959
990 990 a, g, t dbSNP:773329997
993 993 c, g dbSNP:772015673
1001 1001 c, t dbSNP:2069460
1002 1002 a, c, g dbSNP:371735422
1010 1010 a, c, t dbSNP:368178302
1011 1011 a, g dbSNP:79627316
1025 1025 a, g dbSNP:746908389
1043 1043 a, c dbSNP:777405337
1046 1046 c, t dbSNP:775198732
1072 1072 a, g dbSNP:554235263
1082 1082 c, t dbSNP:35051446
1089 1089 c, g dbSNP:575163799
1111 1111 c, t dbSNP:2069461
1112 1112 a, g dbSNP:9278
1114 1114 a, g dbSNP:116863165
1117 1117 g, t dbSNP:566748363
1131 1131 c, t dbSNP:144982250
1146 1146 c, t dbSNP:753001382
1177 1177 g, t dbSNP:529902552

Target ORF information:

RefSeq Version NM_004935
Organism Homo sapiens (human)
Definition Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_004935

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGCAGAAAT ACGAGAAACT GGAAAAGATT GGGGAAGGCA CCTACGGAAC TGTGTTCAAG 
GCCAAAAACC GGGAGACTCA TGAGATCGTG GCTCTGAAAC GGGTGAGGCT GGATGACGAT
GATGAGGGTG TGCCGAGTTC CGCCCTCCGG GAGATCTGCC TACTCAAGGA GCTGAAGCAC
AAGAACATCG TCAGGCTTCA TGACGTCCTG CACAGCGACA AGAAGCTGAC TTTGGTTTTT
GAATTCTGTG ACCAGGACCT GAAGAAGTAT TTTGACAGTT GCAATGGTGA CCTCGATCCT
GAGATTGTAA AGTCATTCCT CTTCCAGCTA CTAAAAGGGC TGGGATTCTG TCATAGCCGC
AATGTGCTAC ACAGGGACCT GAAGCCCCAG AACCTGCTAA TAAACAGGAA TGGGGAGCTG
AAATTGGCTG ATTTTGGCCT GGCTCGAGCC TTTGGGATTC CCGTCCGCTG TTACTCAGCT
GAGGTGGTCA CACTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC
ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTTGCAG AGCTGGCCAA TGCTGGGCGG
CCTCTTTTTC CCGGCAATGA TGTCGATGAC CAGTTGAAGA GGATCTTCCG ACTGCTGGGG
ACGCCCACCG AGGAGCAGTG GCCCTCTATG ACCAAGCTGC CAGACTATAA GCCCTATCCG
ATGTACCCGG CCACAACATC CCTGGTGAAC GTCGTGCCCA AACTCAATGC CACAGGGAGG
GATCTGCTGC AGAACCTTCT GAAGTGTAAC CCTGTCCAGC GTATCTCAGC AGAAGAGGCC
CTGCAGCACC CCTACTTCTC CGACTTCTGT CCGCCCTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.