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MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) [Homo sapiens (human)]

Gene Symbol MAD2L2
Entrez Gene ID 10459
Full Name MAD2 mitotic arrest deficient-like 2 (yeast)
Synonyms MAD2B, POLZ2, REV7
General protein information
Preferred Names
mitotic spindle assembly checkpoint protein MAD2B
Names
mitotic spindle assembly checkpoint protein MAD2B
hREV7
REV7 homolog
MAD2-like protein 2
mitotic arrest deficient homolog-like 2
mitotic arrest deficient 2-like protein 2
polymerase (DNA-directed), zeta 2, accessory subunit
MAD2 (mitotic arrest deficient, yeast, homolog)-like 2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36

Summary The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

604094

Disorder Html:





The following MAD2L2 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAD2L2 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17491 XM_011540507 PREDICTED: Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.3
$199
OHu17491 NM_006341 Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.3
$199
OHu17491 NM_001127325 Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.3
$199

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu17491
Accession Version XM_011540507.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 636bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product mitotic spindle assembly checkpoint protein MAD2B isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
ATGACCACGC TCACACGACA AGACCTCAAC TTTGGCCAAG TGGTGGCCGA TGTGCTCTGC 
GAGTTCCTGG AGGTGGCTGT GCATCTCATC CTCTACGTGC GCGAGGTCTA CCCCGTGGGC
ATCTTCCAGA AACGCAAGAA GTACAACGTG CCGGTCCAGA TGTCCTGCCA CCCGGAGCTG
AATCAGTATA TCCAGGACAC GCTGCACTGC GTCAAGCCAC TCCTGGAGAA GAATGATGTG
GAGAAAGTGG TGGTGGTGAT TTTGGATAAA GAGCACCGCC CAGTGGAGAA ATTCGTCTTT
GAGATCACCC AGCCTCCACT GCTGTCCATC AGCTCAGACT CGCTGTTGTC TCATGTGGAG
CAGCTGCTCC GGGCCTTCAT CCTGAAGATC AGCGTGTGCG ATGCCGTCCT GGACCACAAC
CCCCCAGGCT GTACCTTCAC AGTCCTGGTG CACACGAGAG AAGCCGCCAC TCGCAACATG
GAGAAGATCC AGGTCATCAA GGATTTCCCC TGGATCCTGG CGGATGAGCA GGATGTCCAC
ATGCATGACC CCCGGCTGAT ACCACTAAAA ACCATGACGT CGGACATTTT AAAGATGCAG
CTTTACGTGG AAGAGCGCGC TCATAAAGGC AGCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011538809.1
CDS50..685
Misc Feature(1)86..595(+)
Translation
Position Chain Variation Link
44 44 a, g dbSNP:746084531
45 45 g, t dbSNP:759324529
49 49 g, t dbSNP:774360013
50 50 -, agga dbSNP:754389402
61 61 a, c, t dbSNP:199649788
62 62 a, g dbSNP:752166135
65 65 a, c, g dbSNP:758835270
67 67 a, g dbSNP:538793362
69 69 a, g dbSNP:766076473
82 82 c, t dbSNP:760293423
93 93 g, t dbSNP:754192638
98 98 a, g dbSNP:373974519
100 100 c, t dbSNP:137992567
109 109 c, g dbSNP:565729007
140 140 c, t dbSNP:751185414
152 152 a, g dbSNP:200358078
153 153 a, g dbSNP:762440840
157 157 c, t dbSNP:532070176
160 160 c, t dbSNP:765159021
163 163 c, t dbSNP:759283688
164 164 a, g dbSNP:146185443
166 166 a, g dbSNP:770829171
169 169 c, t dbSNP:761019113
170 170 a, g dbSNP:773563801
183 183 a, g dbSNP:772290930
187 187 a, g dbSNP:371290479
198 198 a, t dbSNP:779317983
208 208 a, g dbSNP:765974447
220 220 c, g dbSNP:773571957
222 222 c, t dbSNP:767807551
223 223 a, g dbSNP:140482494
249 249 c, t dbSNP:377687352
250 250 a, g dbSNP:768584114
251 251 c, t dbSNP:147937370
259 259 c, t dbSNP:373270586
260 260 a, g dbSNP:528545179
277 277 a, g dbSNP:746167583
284 284 c, g dbSNP:757076066
307 307 -, g dbSNP:367892666
321 321 a, g dbSNP:751276389
323 323 c, t dbSNP:778083174
326 326 a, c, t dbSNP:367637499
327 327 a, g dbSNP:151024263
328 328 c, t dbSNP:759600891
343 343 c, t dbSNP:754384497
344 344 a, g dbSNP:766730327
356 356 a, c, t dbSNP:773498548
357 357 c, t dbSNP:767890687
381 381 c, g dbSNP:762759848
383 383 c, t dbSNP:749494169
391 391 a, g dbSNP:780062910
392 392 c, t dbSNP:756203983
403 403 a, c, t dbSNP:542007676
420 420 a, g dbSNP:757723800
423 423 c, g dbSNP:751926997
442 442 c, t dbSNP:764536092
448 448 c, t dbSNP:2233020
454 454 c, t dbSNP:553279720
455 455 a, g dbSNP:771992289
463 463 c, t dbSNP:765865207
470 470 c, t dbSNP:760176047
474 474 c, g dbSNP:773139319
478 478 c, t dbSNP:530535641
482 482 a, g dbSNP:751016876
485 485 g, t dbSNP:763486809
489 489 c, g dbSNP:758403906
501 501 a, t dbSNP:752575348
504 504 c, t dbSNP:139303308
505 505 a, g dbSNP:759350282
514 514 c, t dbSNP:776999328
515 515 a, g dbSNP:766668415
522 522 a, g dbSNP:760862974
544 544 c, t dbSNP:368726339
570 570 c, t dbSNP:763423884
571 571 a, g dbSNP:775870279
573 573 a, g dbSNP:770136702
582 582 a, g dbSNP:746736885
585 585 c, t dbSNP:777238058
588 588 a, g dbSNP:771619761
598 598 c, t dbSNP:747572072
602 602 c, t dbSNP:779016176
603 603 a, g dbSNP:559422464
613 613 a, g dbSNP:753797915
626 626 a, g dbSNP:372770438
627 627 c, t dbSNP:755805030
628 628 a, g dbSNP:28924114
631 631 a, g dbSNP:141637184
633 633 a, g dbSNP:761970716
654 654 a, g dbSNP:745600168
655 655 c, t dbSNP:143263619
656 656 a, g dbSNP:757456103
658 658 a, g dbSNP:578142640
659 659 c, g dbSNP:764213016
665 665 c, t dbSNP:142776270
666 666 a, g dbSNP:753211809
667 667 c, t dbSNP:770656293
668 668 a, g dbSNP:759967644
670 670 c, t dbSNP:776909217
676 676 a, c dbSNP:766737047
693 693 c, t dbSNP:749227342
696 696 c, g dbSNP:761441432
700 700 c, t dbSNP:774088224
711 711 c, t dbSNP:768284310
715 715 a, g dbSNP:748766499
736 736 c, t dbSNP:775589805
737 737 a, c dbSNP:530026451
791 791 c, g dbSNP:556573965
807 807 c, t dbSNP:538577512
808 808 a, g dbSNP:567967378
817 817 c, t dbSNP:548181592
818 818 a, g dbSNP:183103774
819 819 g, t dbSNP:762149813
824 824 a, g dbSNP:565625878
832 832 c, t dbSNP:1045457
888 888 c, t dbSNP:1045462
909 909 c, t dbSNP:191836762
910 910 a, g dbSNP:532203952

Target ORF information:

RefSeq Version XM_011540507
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011540507

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGACCACGC TCACACGACA AGACCTCAAC TTTGGCCAAG TGGTGGCCGA TGTGCTCTGC 
GAGTTCCTGG AGGTGGCTGT GCATCTCATC CTCTACGTGC GCGAGGTCTA CCCCGTGGGC
ATCTTCCAGA AACGCAAGAA GTACAACGTG CCGGTCCAGA TGTCCTGCCA CCCGGAGCTG
AATCAGTATA TCCAGGACAC GCTGCACTGC GTCAAGCCAC TCCTGGAGAA GAATGATGTG
GAGAAAGTGG TGGTGGTGAT TTTGGATAAA GAGCACCGCC CAGTGGAGAA ATTCGTCTTT
GAGATCACCC AGCCTCCACT GCTGTCCATC AGCTCAGACT CGCTGTTGTC TCATGTGGAG
CAGCTGCTCC GGGCCTTCAT CCTGAAGATC AGCGTGTGCG ATGCCGTCCT GGACCACAAC
CCCCCAGGCT GTACCTTCAC AGTCCTGGTG CACACGAGAG AAGCCGCCAC TCGCAACATG
GAGAAGATCC AGGTCATCAA GGATTTCCCC TGGATCCTGG CGGATGAGCA GGATGTCCAC
ATGCATGACC CCCGGCTGAT ACCACTAAAA ACCATGACGT CGGACATTTT AAAGATGCAG
CTTTACGTGG AAGAGCGCGC TCATAAAGGC AGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17491
Accession Version NM_006341.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 636bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product mitotic spindle assembly checkpoint protein MAD2B
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF157482.1. On May 13, 2008 this sequence version replaced gi:6006019. Summary: The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF157482.1, AK027327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
ATGACCACGC TCACACGACA AGACCTCAAC TTTGGCCAAG TGGTGGCCGA TGTGCTCTGC 
GAGTTCCTGG AGGTGGCTGT GCATCTCATC CTCTACGTGC GCGAGGTCTA CCCCGTGGGC
ATCTTCCAGA AACGCAAGAA GTACAACGTG CCGGTCCAGA TGTCCTGCCA CCCGGAGCTG
AATCAGTATA TCCAGGACAC GCTGCACTGC GTCAAGCCAC TCCTGGAGAA GAATGATGTG
GAGAAAGTGG TGGTGGTGAT TTTGGATAAA GAGCACCGCC CAGTGGAGAA ATTCGTCTTT
GAGATCACCC AGCCTCCACT GCTGTCCATC AGCTCAGACT CGCTGTTGTC TCATGTGGAG
CAGCTGCTCC GGGCCTTCAT CCTGAAGATC AGCGTGTGCG ATGCCGTCCT GGACCACAAC
CCCCCAGGCT GTACCTTCAC AGTCCTGGTG CACACGAGAG AAGCCGCCAC TCGCAACATG
GAGAAGATCC AGGTCATCAA GGATTTCCCC TGGATCCTGG CGGATGAGCA GGATGTCCAC
ATGCATGACC CCCGGCTGAT ACCACTAAAA ACCATGACGT CGGACATTTT AAAGATGCAG
CTTTACGTGG AAGAGCGCGC TCATAAAGGC AGCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_006332.3
CDS189..824
Misc Feature(1)39..41(+)
Misc Feature(2)225..734(+)
Misc Feature(3)249..653(+)
Misc Feature(4)636..821(+)
Exon (1)1..176
Gene:MAD2L2
Gene Synonym:
Exon (2)177..228
Gene:MAD2L2
Gene Synonym:
Exon (3)229..347
Gene:MAD2L2
Gene Synonym:
Exon (4)348..419
Gene:MAD2L2
Gene Synonym:
Exon (5)420..520
Gene:MAD2L2
Gene Synonym:
Exon (6)521..615
Gene:MAD2L2
Gene Synonym:
Exon (7)616..689
Gene:MAD2L2
Gene Synonym:
Exon (8)690..782
Gene:MAD2L2
Gene Synonym:
Exon (9)783..1119
Gene:MAD2L2
Gene Synonym:
Translation
Position Chain Variation Link
2 2 c, t dbSNP:187547285
27 27 c, g dbSNP:28924097
28 28 a, g dbSNP:576375990
110 110 a, c, g dbSNP:750637351
118 118 a, c dbSNP:554627310
183 183 a, g dbSNP:746084531
184 184 g, t dbSNP:759324529
188 188 g, t dbSNP:774360013
189 189 -, agga dbSNP:754389402
200 200 a, c, t dbSNP:199649788
201 201 a, g dbSNP:752166135
204 204 a, c, g dbSNP:758835270
206 206 a, g dbSNP:538793362
208 208 a, g dbSNP:766076473
221 221 c, t dbSNP:760293423
232 232 g, t dbSNP:754192638
237 237 a, g dbSNP:373974519
239 239 c, t dbSNP:137992567
248 248 c, g dbSNP:565729007
279 279 c, t dbSNP:751185414
291 291 a, g dbSNP:200358078
292 292 a, g dbSNP:762440840
296 296 c, t dbSNP:532070176
299 299 c, t dbSNP:765159021
302 302 c, t dbSNP:759283688
303 303 a, g dbSNP:146185443
305 305 a, g dbSNP:770829171
308 308 c, t dbSNP:761019113
309 309 a, g dbSNP:773563801
322 322 a, g dbSNP:772290930
326 326 a, g dbSNP:371290479
337 337 a, t dbSNP:779317983
347 347 a, g dbSNP:765974447
359 359 c, g dbSNP:773571957
361 361 c, t dbSNP:767807551
362 362 a, g dbSNP:140482494
388 388 c, t dbSNP:377687352
389 389 a, g dbSNP:768584114
390 390 c, t dbSNP:147937370
398 398 c, t dbSNP:373270586
399 399 a, g dbSNP:528545179
416 416 a, g dbSNP:746167583
423 423 c, g dbSNP:757076066
446 446 -, g dbSNP:367892666
460 460 a, g dbSNP:751276389
462 462 c, t dbSNP:778083174
465 465 a, c, t dbSNP:367637499
466 466 a, g dbSNP:151024263
467 467 c, t dbSNP:759600891
482 482 c, t dbSNP:754384497
483 483 a, g dbSNP:766730327
495 495 a, c, t dbSNP:773498548
496 496 c, t dbSNP:767890687
520 520 c, g dbSNP:762759848
522 522 c, t dbSNP:749494169
530 530 a, g dbSNP:780062910
531 531 c, t dbSNP:756203983
542 542 a, c, t dbSNP:542007676
559 559 a, g dbSNP:757723800
562 562 c, g dbSNP:751926997
581 581 c, t dbSNP:764536092
587 587 c, t dbSNP:2233020
593 593 c, t dbSNP:553279720
594 594 a, g dbSNP:771992289
602 602 c, t dbSNP:765865207
609 609 c, t dbSNP:760176047
613 613 c, g dbSNP:773139319
617 617 c, t dbSNP:530535641
621 621 a, g dbSNP:751016876
624 624 g, t dbSNP:763486809
628 628 c, g dbSNP:758403906
640 640 a, t dbSNP:752575348
643 643 c, t dbSNP:139303308
644 644 a, g dbSNP:759350282
653 653 c, t dbSNP:776999328
654 654 a, g dbSNP:766668415
661 661 a, g dbSNP:760862974
683 683 c, t dbSNP:368726339
709 709 c, t dbSNP:763423884
710 710 a, g dbSNP:775870279
712 712 a, g dbSNP:770136702
721 721 a, g dbSNP:746736885
724 724 c, t dbSNP:777238058
727 727 a, g dbSNP:771619761
737 737 c, t dbSNP:747572072
741 741 c, t dbSNP:779016176
742 742 a, g dbSNP:559422464
752 752 a, g dbSNP:753797915
765 765 a, g dbSNP:372770438
766 766 c, t dbSNP:755805030
767 767 a, g dbSNP:28924114
770 770 a, g dbSNP:141637184
772 772 a, g dbSNP:761970716
793 793 a, g dbSNP:745600168
794 794 c, t dbSNP:143263619
795 795 a, g dbSNP:757456103
797 797 a, g dbSNP:578142640
798 798 c, g dbSNP:764213016
804 804 c, t dbSNP:142776270
805 805 a, g dbSNP:753211809
806 806 c, t dbSNP:770656293
807 807 a, g dbSNP:759967644
809 809 c, t dbSNP:776909217
815 815 a, c dbSNP:766737047
832 832 c, t dbSNP:749227342
835 835 c, g dbSNP:761441432
839 839 c, t dbSNP:774088224
850 850 c, t dbSNP:768284310
854 854 a, g dbSNP:748766499
875 875 c, t dbSNP:775589805
876 876 a, c dbSNP:530026451
930 930 c, g dbSNP:556573965
946 946 c, t dbSNP:538577512
947 947 a, g dbSNP:567967378
956 956 c, t dbSNP:548181592
957 957 a, g dbSNP:183103774
958 958 g, t dbSNP:762149813
963 963 a, g dbSNP:565625878
971 971 c, t dbSNP:1045457
1027 1027 c, t dbSNP:1045462
1048 1048 c, t dbSNP:191836762
1049 1049 a, g dbSNP:532203952

Target ORF information:

RefSeq Version NM_006341
Organism Homo sapiens (human)
Definition Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_006341

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGACCACGC TCACACGACA AGACCTCAAC TTTGGCCAAG TGGTGGCCGA TGTGCTCTGC 
GAGTTCCTGG AGGTGGCTGT GCATCTCATC CTCTACGTGC GCGAGGTCTA CCCCGTGGGC
ATCTTCCAGA AACGCAAGAA GTACAACGTG CCGGTCCAGA TGTCCTGCCA CCCGGAGCTG
AATCAGTATA TCCAGGACAC GCTGCACTGC GTCAAGCCAC TCCTGGAGAA GAATGATGTG
GAGAAAGTGG TGGTGGTGAT TTTGGATAAA GAGCACCGCC CAGTGGAGAA ATTCGTCTTT
GAGATCACCC AGCCTCCACT GCTGTCCATC AGCTCAGACT CGCTGTTGTC TCATGTGGAG
CAGCTGCTCC GGGCCTTCAT CCTGAAGATC AGCGTGTGCG ATGCCGTCCT GGACCACAAC
CCCCCAGGCT GTACCTTCAC AGTCCTGGTG CACACGAGAG AAGCCGCCAC TCGCAACATG
GAGAAGATCC AGGTCATCAA GGATTTCCCC TGGATCCTGG CGGATGAGCA GGATGTCCAC
ATGCATGACC CCCGGCTGAT ACCACTAAAA ACCATGACGT CGGACATTTT AAAGATGCAG
CTTTACGTGG AAGAGCGCGC TCATAAAGGC AGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17491
Accession Version NM_001127325.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 636bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product mitotic spindle assembly checkpoint protein MAD2B
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI517654.1 and AF157482.1. Summary: The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) has the 5'-most first exon. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU175468.1, CN302119.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
ATGACCACGC TCACACGACA AGACCTCAAC TTTGGCCAAG TGGTGGCCGA TGTGCTCTGC 
GAGTTCCTGG AGGTGGCTGT GCATCTCATC CTCTACGTGC GCGAGGTCTA CCCCGTGGGC
ATCTTCCAGA AACGCAAGAA GTACAACGTG CCGGTCCAGA TGTCCTGCCA CCCGGAGCTG
AATCAGTATA TCCAGGACAC GCTGCACTGC GTCAAGCCAC TCCTGGAGAA GAATGATGTG
GAGAAAGTGG TGGTGGTGAT TTTGGATAAA GAGCACCGCC CAGTGGAGAA ATTCGTCTTT
GAGATCACCC AGCCTCCACT GCTGTCCATC AGCTCAGACT CGCTGTTGTC TCATGTGGAG
CAGCTGCTCC GGGCCTTCAT CCTGAAGATC AGCGTGTGCG ATGCCGTCCT GGACCACAAC
CCCCCAGGCT GTACCTTCAC AGTCCTGGTG CACACGAGAG AAGCCGCCAC TCGCAACATG
GAGAAGATCC AGGTCATCAA GGATTTCCCC TGGATCCTGG CGGATGAGCA GGATGTCCAC
ATGCATGACC CCCGGCTGAT ACCACTAAAA ACCATGACGT CGGACATTTT AAAGATGCAG
CTTTACGTGG AAGAGCGCGC TCATAAAGGC AGCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001120797.1
CDS222..857
Misc Feature(1)258..767(+)
Misc Feature(2)282..686(+)
Misc Feature(3)669..854(+)
Exon (1)1..209
Gene:MAD2L2
Gene Synonym:
Exon (2)210..261
Gene:MAD2L2
Gene Synonym:
Exon (3)262..380
Gene:MAD2L2
Gene Synonym:
Exon (4)381..452
Gene:MAD2L2
Gene Synonym:
Exon (5)453..553
Gene:MAD2L2
Gene Synonym:
Exon (6)554..648
Gene:MAD2L2
Gene Synonym:
Exon (7)649..722
Gene:MAD2L2
Gene Synonym:
Exon (8)723..815
Gene:MAD2L2
Gene Synonym:
Exon (9)816..1152
Gene:MAD2L2
Gene Synonym:
Translation
Position Chain Variation Link
29 29 c, t dbSNP:551069822
37 37 c, g dbSNP:752940
48 48 a, g dbSNP:562388815
55 55 g, t dbSNP:183507097
125 125 c, t dbSNP:529207034
128 128 c, g dbSNP:370545018
203 203 c, t dbSNP:562031740
216 216 a, g dbSNP:746084531
217 217 g, t dbSNP:759324529
221 221 g, t dbSNP:774360013
222 222 -, agga dbSNP:754389402
233 233 a, c, t dbSNP:199649788
234 234 a, g dbSNP:752166135
237 237 a, c, g dbSNP:758835270
239 239 a, g dbSNP:538793362
241 241 a, g dbSNP:766076473
254 254 c, t dbSNP:760293423
265 265 g, t dbSNP:754192638
270 270 a, g dbSNP:373974519
272 272 c, t dbSNP:137992567
281 281 c, g dbSNP:565729007
312 312 c, t dbSNP:751185414
324 324 a, g dbSNP:200358078
325 325 a, g dbSNP:762440840
329 329 c, t dbSNP:532070176
332 332 c, t dbSNP:765159021
335 335 c, t dbSNP:759283688
336 336 a, g dbSNP:146185443
338 338 a, g dbSNP:770829171
341 341 c, t dbSNP:761019113
342 342 a, g dbSNP:773563801
355 355 a, g dbSNP:772290930
359 359 a, g dbSNP:371290479
370 370 a, t dbSNP:779317983
380 380 a, g dbSNP:765974447
392 392 c, g dbSNP:773571957
394 394 c, t dbSNP:767807551
395 395 a, g dbSNP:140482494
421 421 c, t dbSNP:377687352
422 422 a, g dbSNP:768584114
423 423 c, t dbSNP:147937370
431 431 c, t dbSNP:373270586
432 432 a, g dbSNP:528545179
449 449 a, g dbSNP:746167583
456 456 c, g dbSNP:757076066
479 479 -, g dbSNP:367892666
493 493 a, g dbSNP:751276389
495 495 c, t dbSNP:778083174
498 498 a, c, t dbSNP:367637499
499 499 a, g dbSNP:151024263
500 500 c, t dbSNP:759600891
515 515 c, t dbSNP:754384497
516 516 a, g dbSNP:766730327
528 528 a, c, t dbSNP:773498548
529 529 c, t dbSNP:767890687
553 553 c, g dbSNP:762759848
555 555 c, t dbSNP:749494169
563 563 a, g dbSNP:780062910
564 564 c, t dbSNP:756203983
575 575 a, c, t dbSNP:542007676
592 592 a, g dbSNP:757723800
595 595 c, g dbSNP:751926997
614 614 c, t dbSNP:764536092
620 620 c, t dbSNP:2233020
626 626 c, t dbSNP:553279720
627 627 a, g dbSNP:771992289
635 635 c, t dbSNP:765865207
642 642 c, t dbSNP:760176047
646 646 c, g dbSNP:773139319
650 650 c, t dbSNP:530535641
654 654 a, g dbSNP:751016876
657 657 g, t dbSNP:763486809
661 661 c, g dbSNP:758403906
673 673 a, t dbSNP:752575348
676 676 c, t dbSNP:139303308
677 677 a, g dbSNP:759350282
686 686 c, t dbSNP:776999328
687 687 a, g dbSNP:766668415
694 694 a, g dbSNP:760862974
716 716 c, t dbSNP:368726339
742 742 c, t dbSNP:763423884
743 743 a, g dbSNP:775870279
745 745 a, g dbSNP:770136702
754 754 a, g dbSNP:746736885
757 757 c, t dbSNP:777238058
760 760 a, g dbSNP:771619761
770 770 c, t dbSNP:747572072
774 774 c, t dbSNP:779016176
775 775 a, g dbSNP:559422464
785 785 a, g dbSNP:753797915
798 798 a, g dbSNP:372770438
799 799 c, t dbSNP:755805030
800 800 a, g dbSNP:28924114
803 803 a, g dbSNP:141637184
805 805 a, g dbSNP:761970716
826 826 a, g dbSNP:745600168
827 827 c, t dbSNP:143263619
828 828 a, g dbSNP:757456103
830 830 a, g dbSNP:578142640
831 831 c, g dbSNP:764213016
837 837 c, t dbSNP:142776270
838 838 a, g dbSNP:753211809
839 839 c, t dbSNP:770656293
840 840 a, g dbSNP:759967644
842 842 c, t dbSNP:776909217
848 848 a, c dbSNP:766737047
865 865 c, t dbSNP:749227342
868 868 c, g dbSNP:761441432
872 872 c, t dbSNP:774088224
883 883 c, t dbSNP:768284310
887 887 a, g dbSNP:748766499
908 908 c, t dbSNP:775589805
909 909 a, c dbSNP:530026451
963 963 c, g dbSNP:556573965
979 979 c, t dbSNP:538577512
980 980 a, g dbSNP:567967378
989 989 c, t dbSNP:548181592
990 990 a, g dbSNP:183103774
991 991 g, t dbSNP:762149813
996 996 a, g dbSNP:565625878
1004 1004 c, t dbSNP:1045457
1060 1060 c, t dbSNP:1045462
1081 1081 c, t dbSNP:191836762
1082 1082 a, g dbSNP:532203952

Target ORF information:

RefSeq Version NM_001127325
Organism Homo sapiens (human)
Definition Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127325

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGACCACGC TCACACGACA AGACCTCAAC TTTGGCCAAG TGGTGGCCGA TGTGCTCTGC 
GAGTTCCTGG AGGTGGCTGT GCATCTCATC CTCTACGTGC GCGAGGTCTA CCCCGTGGGC
ATCTTCCAGA AACGCAAGAA GTACAACGTG CCGGTCCAGA TGTCCTGCCA CCCGGAGCTG
AATCAGTATA TCCAGGACAC GCTGCACTGC GTCAAGCCAC TCCTGGAGAA GAATGATGTG
GAGAAAGTGG TGGTGGTGAT TTTGGATAAA GAGCACCGCC CAGTGGAGAA ATTCGTCTTT
GAGATCACCC AGCCTCCACT GCTGTCCATC AGCTCAGACT CGCTGTTGTC TCATGTGGAG
CAGCTGCTCC GGGCCTTCAT CCTGAAGATC AGCGTGTGCG ATGCCGTCCT GGACCACAAC
CCCCCAGGCT GTACCTTCAC AGTCCTGGTG CACACGAGAG AAGCCGCCAC TCGCAACATG
GAGAAGATCC AGGTCATCAA GGATTTCCCC TGGATCCTGG CGGATGAGCA GGATGTCCAC
ATGCATGACC CCCGGCTGAT ACCACTAAAA ACCATGACGT CGGACATTTT AAAGATGCAG
CTTTACGTGG AAGAGCGCGC TCATAAAGGC AGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.