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SLC9A6 cDNA ORF clone, Homo sapiens (human)

Gene Symbol SLC9A6
Entrez Gene ID 10479
Full Name solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
Synonyms MRSA, NHE6
General protein information
Preferred Names
sodium/hydrogen exchanger 6
Names
sodium/hydrogen exchanger 6
Na(+)/H(+) exchanger 6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq26.3

Summary This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]. lac of sum
Disorder MIM:

300231

Disorder Html: Mental retardation, X-linked syndromic, Christianson type, 300243 (3)





The following SLC9A6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC9A6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu10500 XM_006724726 PREDICTED: Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379.00
OHu64047 XM_011531243 PREDICTED: Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $439.00
OHu10500 NM_001177651 Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379.00
OHu19042 NM_001042537 Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $379.00
OHu05504 NM_006359 Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu10500
Accession Version XM_006724726.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1950bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product sodium/hydrogen exchanger 6 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011786.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578838600. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGGACGAGG AGATCGTGTC CGAGAAGCAA GCCGAGGAGA GCCACCGGCA GGACAGCGCC 
AACCTGCTCA TCTTCATCCT GCTGCTCACC CTCACCATTC TCACAATCTG GCTCTTCAAG
CACCGCCGGG CCCGCTTCCT GCACGAAACC GGCCTGGCTA TGATTTATGG TCTTTTGGTG
GGCCTTGTGC TTCGGTATGG CATTCATGTT CCGAGTGATG TAAATAATGT GACCCTGAGC
TGTGAAGTGC AGTCAAGTCC AACTACCTTA CTGGTAAATG TTAGTGGAAA ATTTTATGAG
TATATGCTGA AAGGAGAGAT TAGTTCACAT GAACTCAATA ATGTTCAAGA TAATGAAATG
CTTAGAAAGG TTACTTTTGA TCCAGAAGTA TTTTTCAACA TATTACTTCC TCCTATCATA
TTTTATGCAG GTTATAGCCT GAAAAGGAGA CATTTTTTTC GAAATCTTGG GTCTATCCTA
GCATACGCTT TTCTTGGAAC AGCAATTTCT TGTTTCGTTA TTGGGTCAAT AATGTATGGC
TGTGTAACGC TGATGAAGGT AACGGGACAA CTTGCAGGAG ATTTTTACTT TACAGATTGC
CTACTGTTTG GTGCCATTGT ATCAGCAACT GATCCAGTGA CTGTTCTTGC TATATTCCAC
GAGCTTCAAG TTGATGTTGA ACTCTATGCA CTTCTTTTTG GTGAAAGTGT CCTCAATGAT
GCTGTTGCCA TAGTGCTGTC CTCCTCAATA GTGGCATACC AGCCAGCTGG AGACAACAGT
CACACCTTTG ATGTCACAGC GATGTTCAAG TCTATTGGGA TCTTCCTTGG AATCTTCAGT
GGATCTTTTG CAATGGGTGC TGCTACTGGA GTGGTGACAG CTTTAGTGAC AAAGTTCACC
AAATTACGGG AGTTCCAGTT GTTGGAGACA GGCCTGTTCT TCTTGATGTC CTGGAGTACC
TTCCTCTTGG CTGAAGCATG GGGCTTCACA GGTGTAGTTG CAGTATTGTT TTGTGGCATC
ACACAAGCAC ATTATACGTA TAATAATTTG TCCACGGAGT CTCAGCATAG AACTAAACAG
TTGTTTGAGC TTCTCAATTT CTTGGCAGAG AATTTCATCT TCTCCTACAT GGGGCTGACA
CTGTTCACCT TCCAGAACCA TGTCTTTAAC CCAACATTTG TAGTAGGAGC ATTTGTTGCT
ATTTTCTTGG GAAGAGCTGC CAATATTTAC CCCTTGTCCC TCTTACTTAA TTTGGGTAGA
AGAAGTAAGA TTGGATCAAA TTTTCAACAC ATGATGATGT TTGCTGGCCT TCGTGGTGCA
ATGGCATTTG CCTTGGCCAT TCGAGATACT GCCACTTATG CACGGCAAAT GATGTTCAGC
ACCACGCTTC TGATTGTGTT TTTTACCGTG TGGGTATTTG GTGGTGGCAC CACTGCAATG
CTGTCATGCT TGCATATCAG GGTTGGTGTT GATTCAGACC AAGAACACTT GGGTGTTCCT
GAAAATGAAA GGAGAACTAC CAAAGCAGAG AGTGCTTGGC TTTTCCGGAT GTGGTACAAC
TTTGATCATA ACTATCTGAA GCCTCTGCTG ACCCACAGCG GGCCTCCGCT GACAACAACA
CTCCCTGCCT GCTGTGGACC CATCGCCAGG TGCCTCACCA GCCCCCAGGC TTACGAAAAC
CAGGAACAGT TGAAAGATGA TGATTCTGAT CTTATTCTCA ATGATGGTGA CATCAGTTTG
ACATATGGAG ATTCTACTGT GAACACTGAA CCGGCCACAT CCAGCGCCCC AAGGAGATTT
ATGGGAAACA GTTCTGAAGA TGCCTTGGAT CGGGAGCTTG CATTTGGGGA CCATGAACTG
GTCATTCGAG GAACACGCCT GGTTCTTCCA ATGGATGATT CTGAACCCCC GCTAAATTTG
TTAGATAATA CGAGACATGG TCCAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_006724789.1
CDS92..2041
Misc Feature(1)467..1534(+)
Translation
Position Chain Variation Link
76 76 c, t dbSNP:139299794
118 118 -, g dbSNP:587784398
302 302 c, t dbSNP:587784400
347 347 a, g dbSNP:587784401
393 393 a, g dbSNP:111679379
543 543 -, at dbSNP:730882188
565 565 c, t dbSNP:144316388
620 620 a, g dbSNP:587784402
824 824 g, t dbSNP:55683716
892 892 a, g dbSNP:185192141
947 947 -, ggtgctgct dbSNP:398122849
1007 1007 c, t dbSNP:398124224
1120 1120 a, c dbSNP:142049079
1433 1433 c, t dbSNP:122461162
1574 1574 g, t dbSNP:398123003
1638 1638 a, g dbSNP:146263125
1690 1690 c, t dbSNP:2307131
1858 1858 c, t dbSNP:398124223
2013 2013 g, t dbSNP:587784399
2610 2610 a, g dbSNP:1048463
3230 3230 a, g dbSNP:6528330

Target ORF information:

RefSeq Version XM_006724726
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006724726

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGGACGAGG AGATCGTGTC CGAGAAGCAA GCCGAGGAGA GCCACCGGCA GGACAGCGCC 
AACCTGCTCA TCTTCATCCT GCTGCTCACC CTCACCATTC TCACAATCTG GCTCTTCAAG
CACCGCCGGG CCCGCTTCCT GCACGAAACC GGCCTGGCTA TGATTTATGG TCTTTTGGTG
GGCCTTGTGC TTCGGTATGG CATTCATGTT CCGAGTGATG TAAATAATGT GACCCTGAGC
TGTGAAGTGC AGTCAAGTCC AACTACCTTA CTGGTAAATG TTAGTGGAAA ATTTTATGAG
TATATGCTGA AAGGAGAGAT TAGTTCACAT GAACTCAATA ATGTTCAAGA TAATGAAATG
CTTAGAAAGG TTACTTTTGA TCCAGAAGTA TTTTTCAACA TATTACTTCC TCCTATCATA
TTTTATGCAG GTTATAGCCT GAAAAGGAGA CATTTTTTTC GAAATCTTGG GTCTATCCTA
GCATACGCTT TTCTTGGAAC AGCAATTTCT TGTTTCGTTA TTGGGTCAAT AATGTATGGC
TGTGTAACGC TGATGAAGGT AACGGGACAA CTTGCAGGAG ATTTTTACTT TACAGATTGC
CTACTGTTTG GTGCCATTGT ATCAGCAACT GATCCAGTGA CTGTTCTTGC TATATTCCAC
GAGCTTCAAG TTGATGTTGA ACTCTATGCA CTTCTTTTTG GTGAAAGTGT CCTCAATGAT
GCTGTTGCCA TAGTGCTGTC CTCCTCAATA GTGGCATACC AGCCAGCTGG AGACAACAGT
CACACCTTTG ATGTCACAGC GATGTTCAAG TCTATTGGGA TCTTCCTTGG AATCTTCAGT
GGATCTTTTG CAATGGGTGC TGCTACTGGA GTGGTGACAG CTTTAGTGAC AAAGTTCACC
AAATTACGGG AGTTCCAGTT GTTGGAGACA GGCCTGTTCT TCTTGATGTC CTGGAGTACC
TTCCTCTTGG CTGAAGCATG GGGCTTCACA GGTGTAGTTG CAGTATTGTT TTGTGGCATC
ACACAAGCAC ATTATACGTA TAATAATTTG TCCACGGAGT CTCAGCATAG AACTAAACAG
TTGTTTGAGC TTCTCAATTT CTTGGCAGAG AATTTCATCT TCTCCTACAT GGGGCTGACA
CTGTTCACCT TCCAGAACCA TGTCTTTAAC CCAACATTTG TAGTAGGAGC ATTTGTTGCT
ATTTTCTTGG GAAGAGCTGC CAATATTTAC CCCTTGTCCC TCTTACTTAA TTTGGGTAGA
AGAAGTAAGA TTGGATCAAA TTTTCAACAC ATGATGATGT TTGCTGGCCT TCGTGGTGCA
ATGGCATTTG CCTTGGCCAT TCGAGATACT GCCACTTATG CACGGCAAAT GATGTTCAGC
ACCACGCTTC TGATTGTGTT TTTTACCGTG TGGGTATTTG GTGGTGGCAC CACTGCAATG
CTGTCATGCT TGCATATCAG GGTTGGTGTT GATTCAGACC AAGAACACTT GGGTGTTCCT
GAAAATGAAA GGAGAACTAC CAAAGCAGAG AGTGCTTGGC TTTTCCGGAT GTGGTACAAC
TTTGATCATA ACTATCTGAA GCCTCTGCTG ACCCACAGCG GGCCTCCGCT GACAACAACA
CTCCCTGCCT GCTGTGGACC CATCGCCAGG TGCCTCACCA GCCCCCAGGC TTACGAAAAC
CAGGAACAGT TGAAAGATGA TGATTCTGAT CTTATTCTCA ATGATGGTGA CATCAGTTTG
ACATATGGAG ATTCTACTGT GAACACTGAA CCGGCCACAT CCAGCGCCCC AAGGAGATTT
ATGGGAAACA GTTCTGAAGA TGCCTTGGAT CGGGAGCTTG CATTTGGGGA CCATGAACTG
GTCATTCGAG GAACACGCCT GGTTCTTCCA ATGGATGATT CTGAACCCCC GCTAAATTTG
TTAGATAATA CGAGACATGG TCCAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu64047
Accession Version XM_011531243.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1854bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product sodium/hydrogen exchanger 6 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011786.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGGACGAGG AGATCGTGTC CGAGAAGCAA GCCGAGGAGA GCCACCGGCA GGACAGCGCC 
AACCTGCTCA TCTTCATCCT GCTGCTCACC CTCACCATTC TCACAATCTG GCTCTTCAAG
CACCGCCGGG CCCGCTTCCT GCACGAAACC GGCCTGGCTA TGATTTATGG TCTTTTGGTG
GGCCTTGTGC TTCGGTATGG CATTCATGTT CCGAGTGATG TAAATAATGT GACCCTGAGC
TGTGAAGTGC AGTCAAGTCC AACTACCTTA CTGGTTACTT TTGATCCAGA AGTATTTTTC
AACATATTAC TTCCTCCTAT CATATTTTAT GCAGGTTATA GCCTGAAAAG GAGACATTTT
TTTCGAAATC TTGGGTCTAT CCTAGCATAC GCTTTTCTTG GAACAGCAAT TTCTTGTTTC
GTTATTGGGT CAATAATGTA TGGCTGTGTA ACGCTGATGA AGGTAACGGG ACAACTTGCA
GGAGATTTTT ACTTTACAGA TTGCCTACTG TTTGGTGCCA TTGTATCAGC AACTGATCCA
GTGACTGTTC TTGCTATATT CCACGAGCTT CAAGTTGATG TTGAACTCTA TGCACTTCTT
TTTGGTGAAA GTGTCCTCAA TGATGCTGTT GCCATAGTGC TGTCCTCCTC AATAGTGGCA
TACCAGCCAG CTGGAGACAA CAGTCACACC TTTGATGTCA CAGCGATGTT CAAGTCTATT
GGGATCTTCC TTGGAATCTT CAGTGGATCT TTTGCAATGG GTGCTGCTAC TGGAGTGGTG
ACAGCTTTAG TGACAAAGTT CACCAAATTA CGGGAGTTCC AGTTGTTGGA GACAGGCCTG
TTCTTCTTGA TGTCCTGGAG TACCTTCCTC TTGGCTGAAG CATGGGGCTT CACAGGTGTA
GTTGCAGTAT TGTTTTGTGG CATCACACAA GCACATTATA CGTATAATAA TTTGTCCACG
GAGTCTCAGC ATAGAACTAA ACAGTTGTTT GAGCTTCTCA ATTTCTTGGC AGAGAATTTC
ATCTTCTCCT ACATGGGGCT GACACTGTTC ACCTTCCAGA ACCATGTCTT TAACCCAACA
TTTGTAGTAG GAGCATTTGT TGCTATTTTC TTGGGAAGAG CTGCCAATAT TTACCCCTTG
TCCCTCTTAC TTAATTTGGG TAGAAGAAGT AAGATTGGAT CAAATTTTCA ACACATGATG
ATGTTTGCTG GCCTTCGTGG TGCAATGGCA TTTGCCTTGG CCATTCGAGA TACTGCCACT
TATGCACGGC AAATGATGTT CAGCACCACG CTTCTGATTG TGTTTTTTAC CGTGTGGGTA
TTTGGTGGTG GCACCACTGC AATGCTGTCA TGCTTGCATA TCAGGGTTGG TGTTGATTCA
GACCAAGAAC ACTTGGGTGT TCCTGAAAAT GAAAGGAGAA CTACCAAAGC AGAGAGTGCT
TGGCTTTTCC GGATGTGGTA CAACTTTGAT CATAACTATC TGAAGCCTCT GCTGACCCAC
AGCGGGCCTC CGCTGACAAC AACACTCCCT GCCTGCTGTG GACCCATCGC CAGGTGCCTC
ACCAGCCCCC AGGCTTACGA AAACCAGGAA CAGTTGAAAG ATGATGATTC TGATCTTATT
CTCAATGATG GTGACATCAG TTTGACATAT GGAGATTCTA CTGTGAACAC TGAACCGGCC
ACATCCAGCG CCCCAAGGAG ATTTATGGGA AACAGTTCTG AAGATGCCTT GGATCGGGAG
CTTGCATTTG GGGACCATGA ACTGGTCATT CGAGGAACAC GCCTGGTTCT TCCAATGGAT
GATTCTGAAC CCCCGCTAAA TTTGTTAGAT AATACGAGAC ATGGTCCAGC CTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011529545.1
CDS81..1934
Misc Feature(1)360..1427(+)
Translation
Position Chain Variation Link
65 65 c, t dbSNP:139299794
107 107 -, g dbSNP:587784398
291 291 c, t dbSNP:587784400
336 336 a, g dbSNP:587784401
436 436 -, at dbSNP:730882188
458 458 c, t dbSNP:144316388
513 513 a, g dbSNP:587784402
717 717 g, t dbSNP:55683716
785 785 a, g dbSNP:185192141
840 840 -, ggtgctgct dbSNP:398122849
900 900 c, t dbSNP:398124224
1013 1013 a, c dbSNP:142049079
1326 1326 c, t dbSNP:122461162
1467 1467 g, t dbSNP:398123003
1531 1531 a, g dbSNP:146263125
1583 1583 c, t dbSNP:2307131
1751 1751 c, t dbSNP:398124223
1906 1906 g, t dbSNP:587784399
2503 2503 a, g dbSNP:1048463
3123 3123 a, g dbSNP:6528330

Target ORF information:

RefSeq Version XM_011531243
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531243

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGGACGAGG AGATCGTGTC CGAGAAGCAA GCCGAGGAGA GCCACCGGCA GGACAGCGCC 
AACCTGCTCA TCTTCATCCT GCTGCTCACC CTCACCATTC TCACAATCTG GCTCTTCAAG
CACCGCCGGG CCCGCTTCCT GCACGAAACC GGCCTGGCTA TGATTTATGG TCTTTTGGTG
GGCCTTGTGC TTCGGTATGG CATTCATGTT CCGAGTGATG TAAATAATGT GACCCTGAGC
TGTGAAGTGC AGTCAAGTCC AACTACCTTA CTGGTTACTT TTGATCCAGA AGTATTTTTC
AACATATTAC TTCCTCCTAT CATATTTTAT GCAGGTTATA GCCTGAAAAG GAGACATTTT
TTTCGAAATC TTGGGTCTAT CCTAGCATAC GCTTTTCTTG GAACAGCAAT TTCTTGTTTC
GTTATTGGGT CAATAATGTA TGGCTGTGTA ACGCTGATGA AGGTAACGGG ACAACTTGCA
GGAGATTTTT ACTTTACAGA TTGCCTACTG TTTGGTGCCA TTGTATCAGC AACTGATCCA
GTGACTGTTC TTGCTATATT CCACGAGCTT CAAGTTGATG TTGAACTCTA TGCACTTCTT
TTTGGTGAAA GTGTCCTCAA TGATGCTGTT GCCATAGTGC TGTCCTCCTC AATAGTGGCA
TACCAGCCAG CTGGAGACAA CAGTCACACC TTTGATGTCA CAGCGATGTT CAAGTCTATT
GGGATCTTCC TTGGAATCTT CAGTGGATCT TTTGCAATGG GTGCTGCTAC TGGAGTGGTG
ACAGCTTTAG TGACAAAGTT CACCAAATTA CGGGAGTTCC AGTTGTTGGA GACAGGCCTG
TTCTTCTTGA TGTCCTGGAG TACCTTCCTC TTGGCTGAAG CATGGGGCTT CACAGGTGTA
GTTGCAGTAT TGTTTTGTGG CATCACACAA GCACATTATA CGTATAATAA TTTGTCCACG
GAGTCTCAGC ATAGAACTAA ACAGTTGTTT GAGCTTCTCA ATTTCTTGGC AGAGAATTTC
ATCTTCTCCT ACATGGGGCT GACACTGTTC ACCTTCCAGA ACCATGTCTT TAACCCAACA
TTTGTAGTAG GAGCATTTGT TGCTATTTTC TTGGGAAGAG CTGCCAATAT TTACCCCTTG
TCCCTCTTAC TTAATTTGGG TAGAAGAAGT AAGATTGGAT CAAATTTTCA ACACATGATG
ATGTTTGCTG GCCTTCGTGG TGCAATGGCA TTTGCCTTGG CCATTCGAGA TACTGCCACT
TATGCACGGC AAATGATGTT CAGCACCACG CTTCTGATTG TGTTTTTTAC CGTGTGGGTA
TTTGGTGGTG GCACCACTGC AATGCTGTCA TGCTTGCATA TCAGGGTTGG TGTTGATTCA
GACCAAGAAC ACTTGGGTGT TCCTGAAAAT GAAAGGAGAA CTACCAAAGC AGAGAGTGCT
TGGCTTTTCC GGATGTGGTA CAACTTTGAT CATAACTATC TGAAGCCTCT GCTGACCCAC
AGCGGGCCTC CGCTGACAAC AACACTCCCT GCCTGCTGTG GACCCATCGC CAGGTGCCTC
ACCAGCCCCC AGGCTTACGA AAACCAGGAA CAGTTGAAAG ATGATGATTC TGATCTTATT
CTCAATGATG GTGACATCAG TTTGACATAT GGAGATTCTA CTGTGAACAC TGAACCGGCC
ACATCCAGCG CCCCAAGGAG ATTTATGGGA AACAGTTCTG AAGATGCCTT GGATCGGGAG
CTTGCATTTG GGGACCATGA ACTGGTCATT CGAGGAACAC GCCTGGTTCT TCCAATGGAT
GATTCTGAAC CCCCGCTAAA TTTGTTAGAT AATACGAGAC ATGGTCCAGC CTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10500
Accession Version NM_001177651.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1950bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product sodium/hydrogen exchanger 6 isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC308430.1, AK300475.1, AL732579.5 and R15803.1. Summary: This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (c) has a shorter N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300475.1, AK316255.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGGACGAGG AGATCGTGTC CGAGAAGCAA GCCGAGGAGA GCCACCGGCA GGACAGCGCC 
AACCTGCTCA TCTTCATCCT GCTGCTCACC CTCACCATTC TCACAATCTG GCTCTTCAAG
CACCGCCGGG CCCGCTTCCT GCACGAAACC GGCCTGGCTA TGATTTATGG TCTTTTGGTG
GGCCTTGTGC TTCGGTATGG CATTCATGTT CCGAGTGATG TAAATAATGT GACCCTGAGC
TGTGAAGTGC AGTCAAGTCC AACTACCTTA CTGGTAAATG TTAGTGGAAA ATTTTATGAG
TATATGCTGA AAGGAGAGAT TAGTTCACAT GAACTCAATA ATGTTCAAGA TAATGAAATG
CTTAGAAAGG TTACTTTTGA TCCAGAAGTA TTTTTCAACA TATTACTTCC TCCTATCATA
TTTTATGCAG GTTATAGCCT GAAAAGGAGA CATTTTTTTC GAAATCTTGG GTCTATCCTA
GCATACGCTT TTCTTGGAAC AGCAATTTCT TGTTTCGTTA TTGGGTCAAT AATGTATGGC
TGTGTAACGC TGATGAAGGT AACGGGACAA CTTGCAGGAG ATTTTTACTT TACAGATTGC
CTACTGTTTG GTGCCATTGT ATCAGCAACT GATCCAGTGA CTGTTCTTGC TATATTCCAC
GAGCTTCAAG TTGATGTTGA ACTCTATGCA CTTCTTTTTG GTGAAAGTGT CCTCAATGAT
GCTGTTGCCA TAGTGCTGTC CTCCTCAATA GTGGCATACC AGCCAGCTGG AGACAACAGT
CACACCTTTG ATGTCACAGC GATGTTCAAG TCTATTGGGA TCTTCCTTGG AATCTTCAGT
GGATCTTTTG CAATGGGTGC TGCTACTGGA GTGGTGACAG CTTTAGTGAC AAAGTTCACC
AAATTACGGG AGTTCCAGTT GTTGGAGACA GGCCTGTTCT TCTTGATGTC CTGGAGTACC
TTCCTCTTGG CTGAAGCATG GGGCTTCACA GGTGTAGTTG CAGTATTGTT TTGTGGCATC
ACACAAGCAC ATTATACGTA TAATAATTTG TCCACGGAGT CTCAGCATAG AACTAAACAG
TTGTTTGAGC TTCTCAATTT CTTGGCAGAG AATTTCATCT TCTCCTACAT GGGGCTGACA
CTGTTCACCT TCCAGAACCA TGTCTTTAAC CCAACATTTG TAGTAGGAGC ATTTGTTGCT
ATTTTCTTGG GAAGAGCTGC CAATATTTAC CCCTTGTCCC TCTTACTTAA TTTGGGTAGA
AGAAGTAAGA TTGGATCAAA TTTTCAACAC ATGATGATGT TTGCTGGCCT TCGTGGTGCA
ATGGCATTTG CCTTGGCCAT TCGAGATACT GCCACTTATG CACGGCAAAT GATGTTCAGC
ACCACGCTTC TGATTGTGTT TTTTACCGTG TGGGTATTTG GTGGTGGCAC CACTGCAATG
CTGTCATGCT TGCATATCAG GGTTGGTGTT GATTCAGACC AAGAACACTT GGGTGTTCCT
GAAAATGAAA GGAGAACTAC CAAAGCAGAG AGTGCTTGGC TTTTCCGGAT GTGGTACAAC
TTTGATCATA ACTATCTGAA GCCTCTGCTG ACCCACAGCG GGCCTCCGCT GACAACAACA
CTCCCTGCCT GCTGTGGACC CATCGCCAGG TGCCTCACCA GCCCCCAGGC TTACGAAAAC
CAGGAACAGT TGAAAGATGA TGATTCTGAT CTTATTCTCA ATGATGGTGA CATCAGTTTG
ACATATGGAG ATTCTACTGT GAACACTGAA CCGGCCACAT CCAGCGCCCC AAGGAGATTT
ATGGGAAACA GTTCTGAAGA TGCCTTGGAT CGGGAGCTTG CATTTGGGGA CCATGAACTG
GTCATTCGAG GAACACGCCT GGTTCTTCCA ATGGATGATT CTGAACCCCC GCTAAATTTG
TTAGATAATA CGAGACATGG TCCAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001171122.1
CDS111..2060
Misc Feature(1)51..53(+)
Misc Feature(2)486..1553(+)
Exon (1)1..54
Gene:SLC9A6
Gene Synonym:
Exon (2)55..279
Gene:SLC9A6
Gene Synonym:
Exon (3)280..479
Gene:SLC9A6
Gene Synonym:
Exon (4)480..557
Gene:SLC9A6
Gene Synonym:
Exon (5)558..634
Gene:SLC9A6
Gene Synonym:
Exon (6)635..747
Gene:SLC9A6
Gene Synonym:
Exon (7)748..853
Gene:SLC9A6
Gene Synonym:
Exon (8)854..995
Gene:SLC9A6
Gene Synonym:
Exon (9)996..1101
Gene:SLC9A6
Gene Synonym:
Exon (10)1102..1190
Gene:SLC9A6
Gene Synonym:
Exon (11)1191..1304
Gene:SLC9A6
Gene Synonym:
Exon (12)1305..1416
Gene:SLC9A6
Gene Synonym:
Exon (13)1417..1570
Gene:SLC9A6
Gene Synonym:
Exon (14)1571..1601
Gene:SLC9A6
Gene Synonym:
Exon (15)1602..1681
Gene:SLC9A6
Gene Synonym:
Exon (16)1682..1787
Gene:SLC9A6
Gene Synonym:
Exon (17)1788..4605
Gene:SLC9A6
Gene Synonym:
Translation
Position Chain Variation Link
95 95 c, t dbSNP:139299794
137 137 -, g dbSNP:587784398
321 321 c, t dbSNP:587784400
366 366 a, g dbSNP:587784401
412 412 a, g dbSNP:111679379
562 562 -, at dbSNP:730882188
584 584 c, t dbSNP:144316388
639 639 a, g dbSNP:587784402
843 843 g, t dbSNP:55683716
911 911 a, g dbSNP:185192141
966 966 -, ggtgctgct dbSNP:398122849
1026 1026 c, t dbSNP:398124224
1139 1139 a, c dbSNP:142049079
1452 1452 c, t dbSNP:122461162
1593 1593 g, t dbSNP:398123003
1657 1657 a, g dbSNP:146263125
1709 1709 c, t dbSNP:2307131
1877 1877 c, t dbSNP:398124223
2032 2032 g, t dbSNP:587784399
2629 2629 a, g dbSNP:1048463
3249 3249 a, g dbSNP:6528330

Target ORF information:

RefSeq Version NM_001177651
Organism Homo sapiens (human)
Definition Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001177651

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGGACGAGG AGATCGTGTC CGAGAAGCAA GCCGAGGAGA GCCACCGGCA GGACAGCGCC 
AACCTGCTCA TCTTCATCCT GCTGCTCACC CTCACCATTC TCACAATCTG GCTCTTCAAG
CACCGCCGGG CCCGCTTCCT GCACGAAACC GGCCTGGCTA TGATTTATGG TCTTTTGGTG
GGCCTTGTGC TTCGGTATGG CATTCATGTT CCGAGTGATG TAAATAATGT GACCCTGAGC
TGTGAAGTGC AGTCAAGTCC AACTACCTTA CTGGTAAATG TTAGTGGAAA ATTTTATGAG
TATATGCTGA AAGGAGAGAT TAGTTCACAT GAACTCAATA ATGTTCAAGA TAATGAAATG
CTTAGAAAGG TTACTTTTGA TCCAGAAGTA TTTTTCAACA TATTACTTCC TCCTATCATA
TTTTATGCAG GTTATAGCCT GAAAAGGAGA CATTTTTTTC GAAATCTTGG GTCTATCCTA
GCATACGCTT TTCTTGGAAC AGCAATTTCT TGTTTCGTTA TTGGGTCAAT AATGTATGGC
TGTGTAACGC TGATGAAGGT AACGGGACAA CTTGCAGGAG ATTTTTACTT TACAGATTGC
CTACTGTTTG GTGCCATTGT ATCAGCAACT GATCCAGTGA CTGTTCTTGC TATATTCCAC
GAGCTTCAAG TTGATGTTGA ACTCTATGCA CTTCTTTTTG GTGAAAGTGT CCTCAATGAT
GCTGTTGCCA TAGTGCTGTC CTCCTCAATA GTGGCATACC AGCCAGCTGG AGACAACAGT
CACACCTTTG ATGTCACAGC GATGTTCAAG TCTATTGGGA TCTTCCTTGG AATCTTCAGT
GGATCTTTTG CAATGGGTGC TGCTACTGGA GTGGTGACAG CTTTAGTGAC AAAGTTCACC
AAATTACGGG AGTTCCAGTT GTTGGAGACA GGCCTGTTCT TCTTGATGTC CTGGAGTACC
TTCCTCTTGG CTGAAGCATG GGGCTTCACA GGTGTAGTTG CAGTATTGTT TTGTGGCATC
ACACAAGCAC ATTATACGTA TAATAATTTG TCCACGGAGT CTCAGCATAG AACTAAACAG
TTGTTTGAGC TTCTCAATTT CTTGGCAGAG AATTTCATCT TCTCCTACAT GGGGCTGACA
CTGTTCACCT TCCAGAACCA TGTCTTTAAC CCAACATTTG TAGTAGGAGC ATTTGTTGCT
ATTTTCTTGG GAAGAGCTGC CAATATTTAC CCCTTGTCCC TCTTACTTAA TTTGGGTAGA
AGAAGTAAGA TTGGATCAAA TTTTCAACAC ATGATGATGT TTGCTGGCCT TCGTGGTGCA
ATGGCATTTG CCTTGGCCAT TCGAGATACT GCCACTTATG CACGGCAAAT GATGTTCAGC
ACCACGCTTC TGATTGTGTT TTTTACCGTG TGGGTATTTG GTGGTGGCAC CACTGCAATG
CTGTCATGCT TGCATATCAG GGTTGGTGTT GATTCAGACC AAGAACACTT GGGTGTTCCT
GAAAATGAAA GGAGAACTAC CAAAGCAGAG AGTGCTTGGC TTTTCCGGAT GTGGTACAAC
TTTGATCATA ACTATCTGAA GCCTCTGCTG ACCCACAGCG GGCCTCCGCT GACAACAACA
CTCCCTGCCT GCTGTGGACC CATCGCCAGG TGCCTCACCA GCCCCCAGGC TTACGAAAAC
CAGGAACAGT TGAAAGATGA TGATTCTGAT CTTATTCTCA ATGATGGTGA CATCAGTTTG
ACATATGGAG ATTCTACTGT GAACACTGAA CCGGCCACAT CCAGCGCCCC AAGGAGATTT
ATGGGAAACA GTTCTGAAGA TGCCTTGGAT CGGGAGCTTG CATTTGGGGA CCATGAACTG
GTCATTCGAG GAACACGCCT GGTTCTTCCA ATGGATGATT CTGAACCCCC GCTAAATTTG
TTAGATAATA CGAGACATGG TCCAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19042
Accession Version NM_001042537.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2106bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product sodium/hydrogen exchanger 6 isoform a precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB483081.1, AF030409.1, BC035029.1 and R15803.1. This sequence is a reference standard in the RefSeqGene project. Summary: This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035029.1, AK289775.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
ATGGCTCGGC GCGGCTGGCG GCGGGCACCC CTCCGCCGTG GCGTCGGCAG CAGTCCCCGA 
GCCCGCAGGC TCATGCGGCC CCTTTGGTTG CTCCTCGCAG TGGGCGTCTT TGACTGGGCA
GGGGCTTCGG ACGGCGGCGG CGGAGAGGCT AGAGCCATGG ACGAGGAGAT CGTGTCCGAG
AAGCAAGCCG AGGAGAGCCA CCGGCAGGAC AGCGCCAACC TGCTCATCTT CATCCTGCTG
CTCACCCTCA CCATTCTCAC AATCTGGCTC TTCAAGCACC GCCGGGCCCG CTTCCTGCAC
GAAACCGGCC TGGCTATGAT TTATGGTCTT TTGGTGGGCC TTGTGCTTCG GTATGGCATT
CATGTTCCGA GTGATGTAAA TAATGTGACC CTGAGCTGTG AAGTGCAGTC AAGTCCAACT
ACCTTACTGG TAAATGTTAG TGGAAAATTT TATGAGTATA TGCTGAAAGG AGAGATTAGT
TCACATGAAC TCAATAATGT TCAAGATAAT GAAATGCTTA GAAAGGTTAC TTTTGATCCA
GAAGTATTTT TCAACATATT ACTTCCTCCT ATCATATTTT ATGCAGGTTA TAGCCTGAAA
AGGAGACATT TTTTTCGAAA TCTTGGGTCT ATCCTAGCAT ACGCTTTTCT TGGAACAGCA
ATTTCTTGTT TCGTTATTGG GTCAATAATG TATGGCTGTG TAACGCTGAT GAAGGTAACG
GGACAACTTG CAGGAGATTT TTACTTTACA GATTGCCTAC TGTTTGGTGC CATTGTATCA
GCAACTGATC CAGTGACTGT TCTTGCTATA TTCCACGAGC TTCAAGTTGA TGTTGAACTC
TATGCACTTC TTTTTGGTGA AAGTGTCCTC AATGATGCTG TTGCCATAGT GCTGTCCTCC
TCAATAGTGG CATACCAGCC AGCTGGAGAC AACAGTCACA CCTTTGATGT CACAGCGATG
TTCAAGTCTA TTGGGATCTT CCTTGGAATC TTCAGTGGAT CTTTTGCAAT GGGTGCTGCT
ACTGGAGTGG TGACAGCTTT AGTGACAAAG TTCACCAAAT TACGGGAGTT CCAGTTGTTG
GAGACAGGCC TGTTCTTCTT GATGTCCTGG AGTACCTTCC TCTTGGCTGA AGCATGGGGC
TTCACAGGTG TAGTTGCAGT ATTGTTTTGT GGCATCACAC AAGCACATTA TACGTATAAT
AATTTGTCCA CGGAGTCTCA GCATAGAACT AAACAGTTGT TTGAGCTTCT CAATTTCTTG
GCAGAGAATT TCATCTTCTC CTACATGGGG CTGACACTGT TCACCTTCCA GAACCATGTC
TTTAACCCAA CATTTGTAGT AGGAGCATTT GTTGCTATTT TCTTGGGAAG AGCTGCCAAT
ATTTACCCCT TGTCCCTCTT ACTTAATTTG GGTAGAAGAA GTAAGATTGG ATCAAATTTT
CAACACATGA TGATGTTTGC TGGCCTTCGT GGTGCAATGG CATTTGCCTT GGCCATTCGA
GATACTGCCA CTTATGCACG GCAAATGATG TTCAGCACCA CGCTTCTGAT TGTGTTTTTT
ACCGTGTGGG TATTTGGTGG TGGCACCACT GCAATGCTGT CATGCTTGCA TATCAGGGTT
GGTGTTGATT CAGACCAAGA ACACTTGGGT GTTCCTGAAA ATGAAAGGAG AACTACCAAA
GCAGAGAGTG CTTGGCTTTT CCGGATGTGG TACAACTTTG ATCATAACTA TCTGAAGCCT
CTGCTGACCC ACAGCGGGCC TCCGCTGACA ACAACACTCC CTGCCTGCTG TGGACCCATC
GCCAGGTGCC TCACCAGCCC CCAGGCTTAC GAAAACCAGG AACAGTTGAA AGATGATGAT
TCTGATCTTA TTCTCAATGA TGGTGACATC AGTTTGACAT ATGGAGATTC TACTGTGAAC
ACTGAACCGG CCACATCCAG CGCCCCAAGG AGATTTATGG GAAACAGTTC TGAAGATGCC
TTGGATCGGG AGCTTGCATT TGGGGACCAT GAACTGGTCA TTCGAGGAAC ACGCCTGGTT
CTTCCAATGG ATGATTCTGA ACCCCCGCTA AATTTGTTAG ATAATACGAG ACATGGTCCA
GCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001036002.1
CDS77..2182
Misc Feature(1)53..55(+)
Misc Feature(2)608..1675(+)
Exon (1)1..401
Gene:SLC9A6
Gene Synonym:
Exon (2)402..601
Gene:SLC9A6
Gene Synonym:
Exon (3)602..679
Gene:SLC9A6
Gene Synonym:
Exon (4)680..756
Gene:SLC9A6
Gene Synonym:
Exon (5)757..869
Gene:SLC9A6
Gene Synonym:
Exon (6)870..975
Gene:SLC9A6
Gene Synonym:
Exon (7)976..1117
Gene:SLC9A6
Gene Synonym:
Exon (8)1118..1223
Gene:SLC9A6
Gene Synonym:
Exon (9)1224..1312
Gene:SLC9A6
Gene Synonym:
Exon (10)1313..1426
Gene:SLC9A6
Gene Synonym:
Exon (11)1427..1538
Gene:SLC9A6
Gene Synonym:
Exon (12)1539..1692
Gene:SLC9A6
Gene Synonym:
Exon (13)1693..1723
Gene:SLC9A6
Gene Synonym:
Exon (14)1724..1803
Gene:SLC9A6
Gene Synonym:
Exon (15)1804..1909
Gene:SLC9A6
Gene Synonym:
Exon (16)1910..4727
Gene:SLC9A6
Gene Synonym:
Translation
Position Chain Variation Link
101 101 g, t dbSNP:201523857
217 217 c, t dbSNP:139299794
259 259 -, g dbSNP:587784398
443 443 c, t dbSNP:587784400
488 488 a, g dbSNP:587784401
534 534 a, g dbSNP:111679379
684 684 -, at dbSNP:730882188
706 706 c, t dbSNP:144316388
761 761 a, g dbSNP:587784402
965 965 g, t dbSNP:55683716
1033 1033 a, g dbSNP:185192141
1088 1088 -, ggtgctgct dbSNP:398122849
1148 1148 c, t dbSNP:398124224
1261 1261 a, c dbSNP:142049079
1574 1574 c, t dbSNP:122461162
1715 1715 g, t dbSNP:398123003
1779 1779 a, g dbSNP:146263125
1831 1831 c, t dbSNP:2307131
1999 1999 c, t dbSNP:398124223
2154 2154 g, t dbSNP:587784399
2751 2751 a, g dbSNP:1048463
3371 3371 a, g dbSNP:6528330

Target ORF information:

RefSeq Version NM_001042537
Organism Homo sapiens (human)
Definition Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001042537

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
ATGGCTCGGC GCGGCTGGCG GCGGGCACCC CTCCGCCGTG GCGTCGGCAG CAGTCCCCGA 
GCCCGCAGGC TCATGCGGCC CCTTTGGTTG CTCCTCGCAG TGGGCGTCTT TGACTGGGCA
GGGGCTTCGG ACGGCGGCGG CGGAGAGGCT AGAGCCATGG ACGAGGAGAT CGTGTCCGAG
AAGCAAGCCG AGGAGAGCCA CCGGCAGGAC AGCGCCAACC TGCTCATCTT CATCCTGCTG
CTCACCCTCA CCATTCTCAC AATCTGGCTC TTCAAGCACC GCCGGGCCCG CTTCCTGCAC
GAAACCGGCC TGGCTATGAT TTATGGTCTT TTGGTGGGCC TTGTGCTTCG GTATGGCATT
CATGTTCCGA GTGATGTAAA TAATGTGACC CTGAGCTGTG AAGTGCAGTC AAGTCCAACT
ACCTTACTGG TAAATGTTAG TGGAAAATTT TATGAGTATA TGCTGAAAGG AGAGATTAGT
TCACATGAAC TCAATAATGT TCAAGATAAT GAAATGCTTA GAAAGGTTAC TTTTGATCCA
GAAGTATTTT TCAACATATT ACTTCCTCCT ATCATATTTT ATGCAGGTTA TAGCCTGAAA
AGGAGACATT TTTTTCGAAA TCTTGGGTCT ATCCTAGCAT ACGCTTTTCT TGGAACAGCA
ATTTCTTGTT TCGTTATTGG GTCAATAATG TATGGCTGTG TAACGCTGAT GAAGGTAACG
GGACAACTTG CAGGAGATTT TTACTTTACA GATTGCCTAC TGTTTGGTGC CATTGTATCA
GCAACTGATC CAGTGACTGT TCTTGCTATA TTCCACGAGC TTCAAGTTGA TGTTGAACTC
TATGCACTTC TTTTTGGTGA AAGTGTCCTC AATGATGCTG TTGCCATAGT GCTGTCCTCC
TCAATAGTGG CATACCAGCC AGCTGGAGAC AACAGTCACA CCTTTGATGT CACAGCGATG
TTCAAGTCTA TTGGGATCTT CCTTGGAATC TTCAGTGGAT CTTTTGCAAT GGGTGCTGCT
ACTGGAGTGG TGACAGCTTT AGTGACAAAG TTCACCAAAT TACGGGAGTT CCAGTTGTTG
GAGACAGGCC TGTTCTTCTT GATGTCCTGG AGTACCTTCC TCTTGGCTGA AGCATGGGGC
TTCACAGGTG TAGTTGCAGT ATTGTTTTGT GGCATCACAC AAGCACATTA TACGTATAAT
AATTTGTCCA CGGAGTCTCA GCATAGAACT AAACAGTTGT TTGAGCTTCT CAATTTCTTG
GCAGAGAATT TCATCTTCTC CTACATGGGG CTGACACTGT TCACCTTCCA GAACCATGTC
TTTAACCCAA CATTTGTAGT AGGAGCATTT GTTGCTATTT TCTTGGGAAG AGCTGCCAAT
ATTTACCCCT TGTCCCTCTT ACTTAATTTG GGTAGAAGAA GTAAGATTGG ATCAAATTTT
CAACACATGA TGATGTTTGC TGGCCTTCGT GGTGCAATGG CATTTGCCTT GGCCATTCGA
GATACTGCCA CTTATGCACG GCAAATGATG TTCAGCACCA CGCTTCTGAT TGTGTTTTTT
ACCGTGTGGG TATTTGGTGG TGGCACCACT GCAATGCTGT CATGCTTGCA TATCAGGGTT
GGTGTTGATT CAGACCAAGA ACACTTGGGT GTTCCTGAAA ATGAAAGGAG AACTACCAAA
GCAGAGAGTG CTTGGCTTTT CCGGATGTGG TACAACTTTG ATCATAACTA TCTGAAGCCT
CTGCTGACCC ACAGCGGGCC TCCGCTGACA ACAACACTCC CTGCCTGCTG TGGACCCATC
GCCAGGTGCC TCACCAGCCC CCAGGCTTAC GAAAACCAGG AACAGTTGAA AGATGATGAT
TCTGATCTTA TTCTCAATGA TGGTGACATC AGTTTGACAT ATGGAGATTC TACTGTGAAC
ACTGAACCGG CCACATCCAG CGCCCCAAGG AGATTTATGG GAAACAGTTC TGAAGATGCC
TTGGATCGGG AGCTTGCATT TGGGGACCAT GAACTGGTCA TTCGAGGAAC ACGCCTGGTT
CTTCCAATGG ATGATTCTGA ACCCCCGCTA AATTTGTTAG ATAATACGAG ACATGGTCCA
GCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu05504
Accession Version NM_006359.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2010bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product sodium/hydrogen exchanger 6 isoform b precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB483081.1, AF030409.1, BC049169.1, BC035029.1 and R15803.1. On Jul 7, 2006 this sequence version replaced gi:5454069. Summary: This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF030409.1, D87743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGGCTCGGC GCGGCTGGCG GCGGGCACCC CTCCGCCGTG GCGTCGGCAG CAGTCCCCGA 
GCCCGCAGGC TCATGCGGCC CCTTTGGTTG CTCCTCGCAG TGGGCGTCTT TGACTGGGCA
GGGGCTTCGG ACGGCGGCGG CGGAGAGGCT AGAGCCATGG ACGAGGAGAT CGTGTCCGAG
AAGCAAGCCG AGGAGAGCCA CCGGCAGGAC AGCGCCAACC TGCTCATCTT CATCCTGCTG
CTCACCCTCA CCATTCTCAC AATCTGGCTC TTCAAGCACC GCCGGGCCCG CTTCCTGCAC
GAAACCGGCC TGGCTATGAT TTATGGTCTT TTGGTGGGCC TTGTGCTTCG GTATGGCATT
CATGTTCCGA GTGATGTAAA TAATGTGACC CTGAGCTGTG AAGTGCAGTC AAGTCCAACT
ACCTTACTGG TTACTTTTGA TCCAGAAGTA TTTTTCAACA TATTACTTCC TCCTATCATA
TTTTATGCAG GTTATAGCCT GAAAAGGAGA CATTTTTTTC GAAATCTTGG GTCTATCCTA
GCATACGCTT TTCTTGGAAC AGCAATTTCT TGTTTCGTTA TTGGGTCAAT AATGTATGGC
TGTGTAACGC TGATGAAGGT AACGGGACAA CTTGCAGGAG ATTTTTACTT TACAGATTGC
CTACTGTTTG GTGCCATTGT ATCAGCAACT GATCCAGTGA CTGTTCTTGC TATATTCCAC
GAGCTTCAAG TTGATGTTGA ACTCTATGCA CTTCTTTTTG GTGAAAGTGT CCTCAATGAT
GCTGTTGCCA TAGTGCTGTC CTCCTCAATA GTGGCATACC AGCCAGCTGG AGACAACAGT
CACACCTTTG ATGTCACAGC GATGTTCAAG TCTATTGGGA TCTTCCTTGG AATCTTCAGT
GGATCTTTTG CAATGGGTGC TGCTACTGGA GTGGTGACAG CTTTAGTGAC AAAGTTCACC
AAATTACGGG AGTTCCAGTT GTTGGAGACA GGCCTGTTCT TCTTGATGTC CTGGAGTACC
TTCCTCTTGG CTGAAGCATG GGGCTTCACA GGTGTAGTTG CAGTATTGTT TTGTGGCATC
ACACAAGCAC ATTATACGTA TAATAATTTG TCCACGGAGT CTCAGCATAG AACTAAACAG
TTGTTTGAGC TTCTCAATTT CTTGGCAGAG AATTTCATCT TCTCCTACAT GGGGCTGACA
CTGTTCACCT TCCAGAACCA TGTCTTTAAC CCAACATTTG TAGTAGGAGC ATTTGTTGCT
ATTTTCTTGG GAAGAGCTGC CAATATTTAC CCCTTGTCCC TCTTACTTAA TTTGGGTAGA
AGAAGTAAGA TTGGATCAAA TTTTCAACAC ATGATGATGT TTGCTGGCCT TCGTGGTGCA
ATGGCATTTG CCTTGGCCAT TCGAGATACT GCCACTTATG CACGGCAAAT GATGTTCAGC
ACCACGCTTC TGATTGTGTT TTTTACCGTG TGGGTATTTG GTGGTGGCAC CACTGCAATG
CTGTCATGCT TGCATATCAG GGTTGGTGTT GATTCAGACC AAGAACACTT GGGTGTTCCT
GAAAATGAAA GGAGAACTAC CAAAGCAGAG AGTGCTTGGC TTTTCCGGAT GTGGTACAAC
TTTGATCATA ACTATCTGAA GCCTCTGCTG ACCCACAGCG GGCCTCCGCT GACAACAACA
CTCCCTGCCT GCTGTGGACC CATCGCCAGG TGCCTCACCA GCCCCCAGGC TTACGAAAAC
CAGGAACAGT TGAAAGATGA TGATTCTGAT CTTATTCTCA ATGATGGTGA CATCAGTTTG
ACATATGGAG ATTCTACTGT GAACACTGAA CCGGCCACAT CCAGCGCCCC AAGGAGATTT
ATGGGAAACA GTTCTGAAGA TGCCTTGGAT CGGGAGCTTG CATTTGGGGA CCATGAACTG
GTCATTCGAG GAACACGCCT GGTTCTTCCA ATGGATGATT CTGAACCCCC GCTAAATTTG
TTAGATAATA CGAGACATGG TCCAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_006350.1
CDS77..2086
Misc Feature(1)53..55(+)
Misc Feature(2)158..220(+)
Misc Feature(3)287..349(+)
Misc Feature(4)383..445(+)
Misc Feature(5)500..562(+)
Misc Feature(6)512..1579(+)
Misc Feature(7)611..673(+)
Misc Feature(8)734..796(+)
Misc Feature(9)812..874(+)
Misc Feature(10)950..1012(+)
Misc Feature(11)1094..1156(+)
Misc Feature(12)1220..1282(+)
Misc Feature(13)1286..1348(+)
Misc Feature(14)1415..1477(+)
Misc Feature(15)1523..1585(+)
Exon (1)1..401
Gene:SLC9A6
Gene Synonym:
Exon (2)402..505
Gene:SLC9A6
Gene Synonym:
Exon (3)506..583
Gene:SLC9A6
Gene Synonym:
Exon (4)584..660
Gene:SLC9A6
Gene Synonym:
Exon (5)661..773
Gene:SLC9A6
Gene Synonym:
Exon (6)774..879
Gene:SLC9A6
Gene Synonym:
Exon (7)880..1021
Gene:SLC9A6
Gene Synonym:
Exon (8)1022..1127
Gene:SLC9A6
Gene Synonym:
Exon (9)1128..1216
Gene:SLC9A6
Gene Synonym:
Exon (10)1217..1330
Gene:SLC9A6
Gene Synonym:
Exon (11)1331..1442
Gene:SLC9A6
Gene Synonym:
Exon (12)1443..1596
Gene:SLC9A6
Gene Synonym:
Exon (13)1597..1627
Gene:SLC9A6
Gene Synonym:
Exon (14)1628..1707
Gene:SLC9A6
Gene Synonym:
Exon (15)1708..1813
Gene:SLC9A6
Gene Synonym:
Exon (16)1814..4631
Gene:SLC9A6
Gene Synonym:
Translation
Position Chain Variation Link
101 101 g, t dbSNP:201523857
217 217 c, t dbSNP:139299794
259 259 -, g dbSNP:587784398
443 443 c, t dbSNP:587784400
488 488 a, g dbSNP:587784401
588 588 -, at dbSNP:730882188
610 610 c, t dbSNP:144316388
665 665 a, g dbSNP:587784402
869 869 g, t dbSNP:55683716
937 937 a, g dbSNP:185192141
992 992 -, ggtgctgct dbSNP:398122849
1052 1052 c, t dbSNP:398124224
1165 1165 a, c dbSNP:142049079
1478 1478 c, t dbSNP:122461162
1619 1619 g, t dbSNP:398123003
1683 1683 a, g dbSNP:146263125
1735 1735 c, t dbSNP:2307131
1903 1903 c, t dbSNP:398124223
2058 2058 g, t dbSNP:587784399
2655 2655 a, g dbSNP:1048463
3275 3275 a, g dbSNP:6528330

Target ORF information:

RefSeq Version NM_006359
Organism Homo sapiens (human)
Definition Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_006359

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGGCTCGGC GCGGCTGGCG GCGGGCACCC CTCCGCCGTG GCGTCGGCAG CAGTCCCCGA 
GCCCGCAGGC TCATGCGGCC CCTTTGGTTG CTCCTCGCAG TGGGCGTCTT TGACTGGGCA
GGGGCTTCGG ACGGCGGCGG CGGAGAGGCT AGAGCCATGG ACGAGGAGAT CGTGTCCGAG
AAGCAAGCCG AGGAGAGCCA CCGGCAGGAC AGCGCCAACC TGCTCATCTT CATCCTGCTG
CTCACCCTCA CCATTCTCAC AATCTGGCTC TTCAAGCACC GCCGGGCCCG CTTCCTGCAC
GAAACCGGCC TGGCTATGAT TTATGGTCTT TTGGTGGGCC TTGTGCTTCG GTATGGCATT
CATGTTCCGA GTGATGTAAA TAATGTGACC CTGAGCTGTG AAGTGCAGTC AAGTCCAACT
ACCTTACTGG TTACTTTTGA TCCAGAAGTA TTTTTCAACA TATTACTTCC TCCTATCATA
TTTTATGCAG GTTATAGCCT GAAAAGGAGA CATTTTTTTC GAAATCTTGG GTCTATCCTA
GCATACGCTT TTCTTGGAAC AGCAATTTCT TGTTTCGTTA TTGGGTCAAT AATGTATGGC
TGTGTAACGC TGATGAAGGT AACGGGACAA CTTGCAGGAG ATTTTTACTT TACAGATTGC
CTACTGTTTG GTGCCATTGT ATCAGCAACT GATCCAGTGA CTGTTCTTGC TATATTCCAC
GAGCTTCAAG TTGATGTTGA ACTCTATGCA CTTCTTTTTG GTGAAAGTGT CCTCAATGAT
GCTGTTGCCA TAGTGCTGTC CTCCTCAATA GTGGCATACC AGCCAGCTGG AGACAACAGT
CACACCTTTG ATGTCACAGC GATGTTCAAG TCTATTGGGA TCTTCCTTGG AATCTTCAGT
GGATCTTTTG CAATGGGTGC TGCTACTGGA GTGGTGACAG CTTTAGTGAC AAAGTTCACC
AAATTACGGG AGTTCCAGTT GTTGGAGACA GGCCTGTTCT TCTTGATGTC CTGGAGTACC
TTCCTCTTGG CTGAAGCATG GGGCTTCACA GGTGTAGTTG CAGTATTGTT TTGTGGCATC
ACACAAGCAC ATTATACGTA TAATAATTTG TCCACGGAGT CTCAGCATAG AACTAAACAG
TTGTTTGAGC TTCTCAATTT CTTGGCAGAG AATTTCATCT TCTCCTACAT GGGGCTGACA
CTGTTCACCT TCCAGAACCA TGTCTTTAAC CCAACATTTG TAGTAGGAGC ATTTGTTGCT
ATTTTCTTGG GAAGAGCTGC CAATATTTAC CCCTTGTCCC TCTTACTTAA TTTGGGTAGA
AGAAGTAAGA TTGGATCAAA TTTTCAACAC ATGATGATGT TTGCTGGCCT TCGTGGTGCA
ATGGCATTTG CCTTGGCCAT TCGAGATACT GCCACTTATG CACGGCAAAT GATGTTCAGC
ACCACGCTTC TGATTGTGTT TTTTACCGTG TGGGTATTTG GTGGTGGCAC CACTGCAATG
CTGTCATGCT TGCATATCAG GGTTGGTGTT GATTCAGACC AAGAACACTT GGGTGTTCCT
GAAAATGAAA GGAGAACTAC CAAAGCAGAG AGTGCTTGGC TTTTCCGGAT GTGGTACAAC
TTTGATCATA ACTATCTGAA GCCTCTGCTG ACCCACAGCG GGCCTCCGCT GACAACAACA
CTCCCTGCCT GCTGTGGACC CATCGCCAGG TGCCTCACCA GCCCCCAGGC TTACGAAAAC
CAGGAACAGT TGAAAGATGA TGATTCTGAT CTTATTCTCA ATGATGGTGA CATCAGTTTG
ACATATGGAG ATTCTACTGT GAACACTGAA CCGGCCACAT CCAGCGCCCC AAGGAGATTT
ATGGGAAACA GTTCTGAAGA TGCCTTGGAT CGGGAGCTTG CATTTGGGGA CCATGAACTG
GTCATTCGAG GAACACGCCT GGTTCTTCCA ATGGATGATT CTGAACCCCC GCTAAATTTG
TTAGATAATA CGAGACATGG TCCAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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