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HOXB13 homeobox B13 [Homo sapiens (human)]

Gene Symbol HOXB13
Entrez Gene ID 10481
Full Name homeobox B13
Synonyms PSGD
General protein information
Preferred Names
homeobox protein Hox-B13
Names
homeobox protein Hox-B13
homeo box B13
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q21.2

Summary This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

604607

Disorder Html:





The following HOXB13 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HOXB13 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu20252 NM_006361 Homo sapiens homeobox B13 (HOXB13), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$309

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu20252
Accession Version NM_006361.5 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 855bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu20252D_COA.pdf (pdf)
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product homeobox protein Hox-B13
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY937237.1 and BC070233.1. This sequence is a reference standard in the RefSeqGene project. On Dec 29, 2005 this sequence version replaced gi:70167332. Summary: This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY937237.1, BC070233.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGAGCCCG GCAATTATGC CACCTTGGAT GGAGCCAAGG ATATCGAAGG CTTGCTGGGA 
GCGGGAGGGG GGCGGAATCT GGTCGCCCAC TCCCCTCTGA CCAGCCACCC AGCGGCGCCT
ACGCTGATGC CTGCTGTCAA CTATGCCCCC TTGGATCTGC CAGGCTCGGC GGAGCCGCCA
AAGCAATGCC ACCCATGCCC TGGGGTGCCC CAGGGGACGT CCCCAGCTCC CGTGCCTTAT
GGTTACTTTG GAGGCGGGTA CTACTCCTGC CGAGTGTCCC GGAGCTCGCT GAAACCCTGT
GCCCAGGCAG CCACCCTGGC CGCGTACCCC GCGGAGACTC CCACGGCCGG GGAAGAGTAC
CCCAGCCGCC CCACTGAGTT TGCCTTCTAT CCGGGATATC CGGGAACCTA CCAGCCTATG
GCCAGTTACC TGGACGTGTC TGTGGTGCAG ACTCTGGGTG CTCCTGGAGA ACCGCGACAT
GACTCCCTGT TGCCTGTGGA CAGTTACCAG TCTTGGGCTC TCGCTGGTGG CTGGAACAGC
CAGATGTGTT GCCAGGGAGA ACAGAACCCA CCAGGTCCCT TTTGGAAGGC AGCATTTGCA
GACTCCAGCG GGCAGCACCC TCCTGACGCC TGCGCCTTTC GTCGCGGCCG CAAGAAACGC
ATTCCGTACA GCAAGGGGCA GTTGCGGGAG CTGGAGCGGG AGTATGCGGC TAACAAGTTC
ATCACCAAGG ACAAGAGGCG CAAGATCTCG GCAGCCACCA GCCTCTCGGA GCGCCAGATT
ACCATCTGGT TTCAGAACCG CCGGGTCAAA GAGAAGAAGG TTCTCGCCAA GGTGAAGAAC
AGCGCTACCC CTTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_006352.2
CDS157..1011
Misc Feature(1)184..525(+)
Misc Feature(2)805..975(+)
Misc Feature(3)805..975(+)
Misc Feature(4)811..963(+)
Exon (1)1..757
Gene:HOXB13
Gene Synonym:
Exon (2)758..3038
Gene:HOXB13
Gene Synonym:
Translation
Position Chain Variation Link
8 8 a, c, t dbSNP:147157748
11 11 a, g dbSNP:538070786
15 15 g, t dbSNP:575381957
18 18 c, g dbSNP:778818195
25 25 a, g dbSNP:556373488
27 27 a, c dbSNP:773544180
65 65 a, c dbSNP:375682349
66 66 a, g dbSNP:373833700
76 76 c, t dbSNP:535584715
81 81 a, g dbSNP:200066609
97 97 a, g dbSNP:566472800
106 106 g, t dbSNP:755645189
110 110 c, t dbSNP:200891371
115 115 a, g dbSNP:767327174
116 116 a, g, t dbSNP:61748976
128 128 c, t dbSNP:751427872
132 132 a, t dbSNP:764053668
150 150 c, t dbSNP:762994956
151 151 a, g dbSNP:375857762
162 162 a, g dbSNP:371544984
163 163 a, c dbSNP:546307661
167 167 g, t dbSNP:776869015
173 173 a, t dbSNP:771173385
179 179 c, t dbSNP:747307642
180 180 c, t dbSNP:748740551
189 189 a, t dbSNP:773581479
218 218 c, t dbSNP:772484566
219 219 a, g dbSNP:368505949
220 220 a, g dbSNP:539706443
223 223 a, g dbSNP:769323553
224 224 a, g dbSNP:745392080
226 226 a, g dbSNP:780947625
230 230 a, g dbSNP:587780165
241 241 g, t dbSNP:756970136
245 245 a, g dbSNP:751338230
246 246 c, g, t dbSNP:561048036
248 248 c, g dbSNP:758169931
252 252 a, t dbSNP:752661579
253 253 a, c dbSNP:79344505
255 255 c, g dbSNP:570672959
262 262 a, c dbSNP:550726919
269 269 a, c, g dbSNP:587780160
271 271 g, t dbSNP:760874697
272 272 a, c dbSNP:773491778
278 278 c, t dbSNP:199799743
296 296 a, g dbSNP:748333323
297 297 c, t dbSNP:774872614
301 301 c, g dbSNP:11551892
316 316 c, t dbSNP:769074510
325 325 g, t dbSNP:745306184
327 327 a, g dbSNP:780859632
332 332 c, t dbSNP:770620686
333 333 a, g dbSNP:779780541
338 338 a, t dbSNP:568967699
339 339 a, g dbSNP:541519790
343 343 g, t dbSNP:758166293
344 344 a, g dbSNP:199813155
352 352 c, t dbSNP:778843798
354 354 a, c dbSNP:754885900
355 355 c, t dbSNP:587780161
361 361 g, t dbSNP:766443552
364 364 a, c, t dbSNP:370934116
365 365 c, t dbSNP:750621041
366 366 c, t dbSNP:768670673
367 367 c, t dbSNP:762197066
371 371 g, t dbSNP:774579054
372 372 a, g dbSNP:769145488
374 374 c, t dbSNP:763353615
375 375 a, g dbSNP:776203446
387 387 a, c dbSNP:770545259
388 388 g, t dbSNP:746542615
395 395 a, g dbSNP:772962401
407 407 a, g dbSNP:138213197
409 409 a, g dbSNP:529392210
410 410 a, g dbSNP:778563157
414 414 c, g dbSNP:754872559
427 427 a, c dbSNP:749195398
433 433 g, t dbSNP:780012601
437 437 a, g dbSNP:756135357
441 441 c, t dbSNP:750529308
444 444 g, t dbSNP:767708021
445 445 a, c dbSNP:757433384
446 446 a, t dbSNP:751865027
451 451 a, c dbSNP:764359688
458 458 c, t dbSNP:763448911
459 459 c, g, t dbSNP:150413396
464 464 c, t dbSNP:760196832
465 465 -, agc dbSNP:767438744
470 470 c, t dbSNP:140492479
473 473 g, t dbSNP:771674803
475 475 c, g dbSNP:747755369
479 479 c, t dbSNP:774095240
480 480 a, g dbSNP:768311961
483 483 c, g dbSNP:749101324
484 484 c, g dbSNP:370361482
486 486 a, c dbSNP:33993186
487 487 a, g dbSNP:745889927
488 488 a, c dbSNP:781117900
489 489 a, g dbSNP:757423683
496 496 a, c dbSNP:751698154
500 500 c, t dbSNP:764401781
501 501 g, t dbSNP:758798025
504 504 c, t dbSNP:753116559
505 505 a, g dbSNP:533641489
506 506 a, g dbSNP:760111060
516 516 c, t dbSNP:777265653
517 517 c, g dbSNP:766909225
522 522 a, c, t dbSNP:8556
524 524 a, g dbSNP:201428095
527 527 c, g dbSNP:762666370
532 532 g, t dbSNP:778047967
539 539 c, t dbSNP:775273363
560 560 a, g dbSNP:769634543
562 562 a, c dbSNP:745800027
564 564 c, t dbSNP:781228991
566 566 a, c dbSNP:770891609
567 567 c, t dbSNP:377339084
570 570 c, g dbSNP:575899185
573 573 c, t dbSNP:758708152
578 578 c, t dbSNP:556045007
592 592 a, g dbSNP:587780162
610 610 a, c dbSNP:140373548
612 612 c, g dbSNP:755437330
613 613 a, g dbSNP:754280897
614 614 g, t dbSNP:766929278
617 617 c, t dbSNP:587780163
630 630 a, g dbSNP:35033273
641 641 c, g dbSNP:751081605
645 645 c, g dbSNP:199561305
646 646 c, t dbSNP:555788633
648 648 a, g dbSNP:762580646
654 654 a, g dbSNP:775189167
655 655 a, g dbSNP:587780164
659 659 -, g dbSNP:759813901
662 662 -, a dbSNP:774435019
663 663 c, t dbSNP:373766741
669 669 c, t dbSNP:9900627
679 679 g, t dbSNP:148649390
682 682 c, g dbSNP:747003841
683 683 a, g dbSNP:539086211
686 686 g, t dbSNP:777986934
698 698 a, g dbSNP:570681642
701 701 c, t dbSNP:772349818
702 702 a, g dbSNP:748353425
719 719 a, g dbSNP:779330626
723 723 c, t dbSNP:143945091
726 726 a, t dbSNP:754258114
736 736 a, t dbSNP:780355420
738 738 c, t dbSNP:201780092
743 743 -, a dbSNP:771483373
745 745 a, g dbSNP:756654236
754 754 g, t dbSNP:750945370
762 762 c, t dbSNP:370633734
770 770 a, g dbSNP:761530565
771 771 c, g dbSNP:766169510
785 785 c, t dbSNP:758190709
789 789 a, c dbSNP:760440566
790 790 a, g, t dbSNP:145059285
799 799 c, t dbSNP:761914407
802 802 g, t dbSNP:375917549
805 805 c, t dbSNP:139475791
806 806 g, t dbSNP:749518336
809 809 a, g dbSNP:775613793
821 821 c, g dbSNP:770172581
834 834 a, g dbSNP:200362093
835 835 c, g dbSNP:781634127
836 836 a, g dbSNP:757776260
841 841 c, t dbSNP:529100627
853 853 a, c, t dbSNP:778481913
863 863 a, c dbSNP:754487444
864 864 a, g dbSNP:555201890
871 871 a, c, g dbSNP:765973015
886 886 a, g dbSNP:372121677
891 891 a, g dbSNP:138675188
893 893 a, g dbSNP:754598240
895 895 c, t dbSNP:750244360
896 896 a, g dbSNP:767502912
903 903 a, c dbSNP:761824576
905 905 c, t dbSNP:751610575
906 906 a, g dbSNP:764201750
909 909 a, g dbSNP:762991673
913 913 a, c dbSNP:775731553
917 917 c, g dbSNP:769938759
925 925 -, g dbSNP:770443137
928 928 c, t dbSNP:759838136
929 929 a, g, t dbSNP:367732101
930 930 a, c dbSNP:771352907
943 943 c, t dbSNP:747483887
955 955 c, t dbSNP:778197145
958 958 a, c dbSNP:768168209
959 959 a, g dbSNP:748782183
960 960 g, t dbSNP:779692736
976 976 g, t dbSNP:755838178
981 981 c, t dbSNP:750156094
982 982 a, g dbSNP:191886930
984 984 c, t dbSNP:757155193
988 988 g, t dbSNP:200997384
998 998 c, g dbSNP:763960333
999 999 c, t dbSNP:763047500
1000 1000 a, g dbSNP:752722523
1005 1005 c, t dbSNP:374736844
1008 1008 -, t dbSNP:398102310
1009 1009 -, t dbSNP:77179853
1019 1019 -, cct dbSNP:779616451
1024 1024 c, t dbSNP:759752190
1026 1026 a, t dbSNP:776879752
1028 1028 c, g dbSNP:771264942
1039 1039 a, c, g dbSNP:371753257
1050 1050 g, t dbSNP:772464950
1059 1059 a, g dbSNP:748771009
1060 1060 a, g dbSNP:779415012
1065 1065 c, g dbSNP:144967504
1068 1068 a, g dbSNP:141179592
1082 1082 a, c dbSNP:187442839
1114 1114 c, g dbSNP:540198896
1126 1126 a, g dbSNP:183620920
1132 1132 c, t dbSNP:748824802
1166 1166 g, t dbSNP:765923303
1224 1224 c, g dbSNP:192244427
1233 1233 c, t dbSNP:552173343
1249 1249 a, g dbSNP:528690447
1312 1312 a, g dbSNP:2280353
1330 1330 a, g dbSNP:2280354
1331 1331 c, t dbSNP:146552906
1336 1336 a, g dbSNP:769323545
1434 1434 c, g dbSNP:562927325
1444 1444 a, g dbSNP:767816878
1454 1454 c, g dbSNP:79982443
1484 1484 g, t dbSNP:543028086
1499 1499 c, g dbSNP:574361767
1532 1532 a, t dbSNP:187003057
1557 1557 a, g dbSNP:144241488
1573 1573 c, t dbSNP:774503212
1625 1625 a, g dbSNP:11653611
1633 1633 a, c dbSNP:558745274
1634 1634 a, c dbSNP:528286447
1674 1674 a, g dbSNP:775551181
1712 1712 -, a dbSNP:762506672
1726 1726 a, g dbSNP:539535707
1744 1744 a, g dbSNP:570975321
1776 1776 c, g dbSNP:550968159
1794 1794 g, t dbSNP:537447730
1873 1873 c, t dbSNP:113568340
1874 1874 c, t dbSNP:548892711
1883 1883 a, g dbSNP:530147382
1891 1891 g, t dbSNP:773169798
1898 1898 c, t dbSNP:771829805
1900 1900 c, g dbSNP:747965531
1902 1902 c, g, t dbSNP:184053751
1906 1906 c, t dbSNP:778797220
1914 1914 -, ct dbSNP:773116234
1927 1927 c, t dbSNP:79214867
1948 1948 a, g dbSNP:754684335
2045 2045 c, t dbSNP:753050808
2103 2103 a, c dbSNP:779583106
2135 2135 c, t dbSNP:552769580
2168 2168 a, c dbSNP:1056656
2169 2169 a, g dbSNP:748913219
2175 2175 a, g dbSNP:371876392
2190 2190 a, g dbSNP:189589365
2241 2241 a, c dbSNP:563065128
2245 2245 c, g dbSNP:542966654
2246 2246 a, g dbSNP:368411572
2249 2249 c, t dbSNP:529786232
2255 2255 a, c dbSNP:755585408
2303 2303 a, c dbSNP:574104328
2338 2338 -, ggc dbSNP:553929053
2344 2344 a, c dbSNP:374232757
2349 2349 c, t dbSNP:560597408
2368 2368 a, g dbSNP:540946232
2382 2382 c, t dbSNP:368424992
2457 2457 a, t dbSNP:779730634
2494 2494 a, g dbSNP:8069269
2508 2508 a, g dbSNP:754351804
2533 2533 a, g dbSNP:8069252
2550 2550 c, g dbSNP:766431405
2582 2582 a, c, g dbSNP:750930408
2583 2583 c, t dbSNP:8065051
2602 2602 c, t dbSNP:3107299
2624 2624 c, g dbSNP:8081840
2628 2628 c, t dbSNP:8065028
2630 2630 a, g dbSNP:142428986
2668 2668 a, t dbSNP:577367530
2694 2694 a, t dbSNP:557502169
2710 2710 c, t dbSNP:768064084
2713 2713 -, t dbSNP:761848733
2731 2731 a, c dbSNP:757620049
2751 2751 c, t dbSNP:148791210
2761 2761 a, g dbSNP:760808647
2770 2770 -, a dbSNP:747139186
2804 2804 a, g dbSNP:61123825
2826 2826 c, g dbSNP:568458574
2834 2834 a, g dbSNP:79812861
2844 2844 c, g dbSNP:145426191
2847 2847 a, c dbSNP:8068732
2849 2849 a, c dbSNP:116931900
2879 2879 g, t dbSNP:8082520
2891 2891 c, t dbSNP:552466056
2913 2913 c, t dbSNP:532742415
2934 2934 a, g dbSNP:8068566
2984 2984 g, t dbSNP:8064432

Target ORF information:

RefSeq Version NM_006361
Organism Homo sapiens (human)
Definition Homo sapiens homeobox B13 (HOXB13), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_006361

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGAGCCCG GCAATTATGC CACCTTGGAT GGAGCCAAGG ATATCGAAGG CTTGCTGGGA 
GCGGGAGGGG GGCGGAATCT GGTCGCCCAC TCCCCTCTGA CCAGCCACCC AGCGGCGCCT
ACGCTGATGC CTGCTGTCAA CTATGCCCCC TTGGATCTGC CAGGCTCGGC GGAGCCGCCA
AAGCAATGCC ACCCATGCCC TGGGGTGCCC CAGGGGACGT CCCCAGCTCC CGTGCCTTAT
GGTTACTTTG GAGGCGGGTA CTACTCCTGC CGAGTGTCCC GGAGCTCGCT GAAACCCTGT
GCCCAGGCAG CCACCCTGGC CGCGTACCCC GCGGAGACTC CCACGGCCGG GGAAGAGTAC
CCCAGCCGCC CCACTGAGTT TGCCTTCTAT CCGGGATATC CGGGAACCTA CCAGCCTATG
GCCAGTTACC TGGACGTGTC TGTGGTGCAG ACTCTGGGTG CTCCTGGAGA ACCGCGACAT
GACTCCCTGT TGCCTGTGGA CAGTTACCAG TCTTGGGCTC TCGCTGGTGG CTGGAACAGC
CAGATGTGTT GCCAGGGAGA ACAGAACCCA CCAGGTCCCT TTTGGAAGGC AGCATTTGCA
GACTCCAGCG GGCAGCACCC TCCTGACGCC TGCGCCTTTC GTCGCGGCCG CAAGAAACGC
ATTCCGTACA GCAAGGGGCA GTTGCGGGAG CTGGAGCGGG AGTATGCGGC TAACAAGTTC
ATCACCAAGG ACAAGAGGCG CAAGATCTCG GCAGCCACCA GCCTCTCGGA GCGCCAGATT
ACCATCTGGT TTCAGAACCG CCGGGTCAAA GAGAAGAAGG TTCTCGCCAA GGTGAAGAAC
AGCGCTACCC CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.