The following SLCO1B1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLCO1B1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 2076bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||solute carrier organic anion transporter family member 1B1
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC020696.1, AF205071.1 and
This sequence is a reference standard in the RefSeqGene project.
On Mar 21, 2009 this sequence version replaced gi:141801825.
Summary: This gene encodes a liver-specific member of the organic
anion transporter family. The encoded protein is a transmembrane
receptor that mediates the sodium-independent uptake of numerous
endogenous compounds including bilirubin, 17-beta-glucuronosyl
estradiol and leukotriene C4. This protein is also involved in the
removal of drug compounds such as statins, bromosulfophthalein and
rifampin from the blood into the hepatocytes. Polymorphisms in the
gene encoding this protein are associated with impaired transporter
function. [provided by RefSeq, Mar 2009].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AF205071.1, AB026257.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: full length.