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DLL3 delta-like 3 (Drosophila) [Homo sapiens (human)]

Gene Symbol DLL3
Entrez Gene ID 10683
Full Name delta-like 3 (Drosophila)
Synonyms SCDO1
General protein information
Preferred Names
delta-like protein 3
Names
delta-like protein 3
delta3
drosophila Delta homolog 3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13

Summary This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

602768

Disorder Html: Spondylocostal dysostosis, autosomal recessive, 1, 277300 (3)





The following DLL3 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DLL3 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu26392 NM_203486 Homo sapiens delta-like 3 (Drosophila) (DLL3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $489
OHu26149 NM_016941 Homo sapiens delta-like 3 (Drosophila) (DLL3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector in pcDNA3.1+/C-(K)DYK $519

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu26392
Accession Version NM_203486.2
Sequence Information ORF Nucleotide Sequence (Length: 1764bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product delta-like protein 3 isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB035825.1, BC000218.2, AK075302.1 and AA865362.1. On May 29, 2008 this sequence version replaced gi:45243560. Summary: This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) has a different splicing pattern at the 3' end compared to transcript variant 1. This results in an isoform (2) with a shorter C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK075302.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGTCTCCC CACGGATGTC CGGGCTCCTC TCCCAGACTG TGATCCTAGC GCTCATTTTC 
CTCCCCCAGA CACGGCCCGC TGGCGTCTTC GAGCTGCAGA TCCACTCTTT CGGGCCGGGT
CCAGGCCCTG GGGCCCCGCG GTCCCCCTGC AGCGCCCGGC TCCCCTGCCG CCTCTTCTTC
AGAGTCTGCC TGAAGCCTGG GCTCTCAGAG GAGGCCGCCG AGTCCCCGTG CGCCCTGGGC
GCGGCGCTGA GTGCGCGCGG ACCGGTCTAC ACCGAGCAGC CCGGAGCGCC CGCGCCTGAT
CTCCCACTGC CCGACGGCCT CTTGCAGGTG CCCTTCCGGG ACGCCTGGCC TGGCACCTTC
TCTTTCATCA TCGAAACCTG GAGAGAGGAG TTAGGAGACC AGATTGGAGG GCCCGCCTGG
AGCCTGCTGG CGCGCGTGGC TGGCAGGCGG CGCTTGGCAG CCGGAGGCCC GTGGGCCCGG
GACATTCAGC GCGCAGGCGC CTGGGAGCTG CGCTTCTCGT ACCGCGCGCG CTGCGAGCCG
CCTGCCGTCG GGACCGCGTG CACGCGCCTC TGCCGTCCGC GCAGCGCCCC CTCGCGGTGC
GGTCCGGGAC TGCGCCCCTG CGCACCGCTC GAGGACGAAT GTGAGGCGCC GCTGGTGTGC
CGAGCAGGCT GCAGCCCTGA GCATGGCTTC TGTGAACAGC CCGGTGAATG CCGATGCCTA
GAGGGCTGGA CTGGACCCCT CTGCACGGTC CCTGTCTCCA CCAGCAGCTG CCTCAGCCCC
AGGGGCCCGT CCTCTGCTAC CACCGGATGC CTTGTCCCTG GGCCTGGGCC CTGTGACGGG
AACCCGTGTG CCAATGGAGG CAGCTGTAGT GAGACACCCA GGTCCTTTGA ATGCACCTGC
CCGCGTGGGT TCTACGGGCT GCGGTGTGAG GTGAGCGGGG TGACATGTGC AGATGGACCC
TGCTTCAACG GCGGCTTGTG TGTCGGGGGT GCAGACCCTG ACTCTGCCTA CATCTGCCAC
TGCCCACCCG GTTTCCAAGG CTCCAACTGT GAGAAGAGGG TGGACCGGTG CAGCCTGCAG
CCATGCCGCA ATGGCGGACT CTGCCTGGAC CTGGGCCACG CCCTGCGCTG CCGCTGCCGC
GCCGGCTTCG CGGGTCCTCG CTGCGAGCAC GACCTGGACG ACTGCGCGGG CCGCGCCTGC
GCTAACGGCG GCACGTGTGT GGAGGGCGGC GGCGCGCACC GCTGCTCCTG CGCGCTGGGC
TTCGGCGGCC GCGACTGCCG CGAGCGCGCG GACCCGTGCG CCGCGCGCCC CTGTGCTCAC
GGCGGCCGCT GCTACGCCCA CTTCTCCGGC CTCGTCTGCG CTTGCGCTCC CGGCTACATG
GGAGCGCGGT GTGAGTTCCC AGTGCACCCC GACGGCGCAA GCGCCTTGCC CGCGGCCCCG
CCGGGCCTCA GGCCCGGGGA CCCTCAGCGC TACCTTTTGC CTCCGGCTCT GGGACTGCTC
GTGGCCGCGG GCGTGGCCGG CGCTGCGCTC TTGCTGGTCC ACGTGCGCCG CCGTGGCCAC
TCCCAGGATG CTGGGTCTCG CTTGCTGGCT GGGACCCCGG AGCCGTCAGT CCACGCACTC
CCGGATGCAC TCAACAACCT AAGGACGCAG GAGGGTTCCG GGGATGGTCC GAGCTCGTCC
GTAGATTGGA ATCGCCCTGA AGATGTAGAC CCTCAAGGGA TTTATGTCAT ATCTGCTCCT
TCCATCTACG CTCGGGAGGC CTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_982353.1
CDS59..1822
Misc Feature(1)134..343(+)
Misc Feature(2)530..802(+)
Misc Feature(3)893..988(+)
Misc Feature(4)1004..1111(+)
Misc Feature(5)1118..1225(+)
Misc Feature(6)1124..1168(+)
Misc Feature(7)1229..1336(+)
Misc Feature(8)1229..1282(+)
Misc Feature(9)1535..1597(+)
Exon (1)1..127
Gene:DLL3
Gene Synonym:
Exon (2)128..409
Gene:DLL3
Gene Synonym:
Exon (3)410..467
Gene:DLL3
Gene Synonym:
Exon (4)468..710
Gene:DLL3
Gene Synonym:
Exon (5)711..928
Gene:DLL3
Gene Synonym:
Exon (6)929..1151
Gene:DLL3
Gene Synonym:
Exon (7)1152..1731
Gene:DLL3
Gene Synonym:
Exon (8)1732..1816
Gene:DLL3
Gene Synonym:
Exon (9)1817..2046
Gene:DLL3
Gene Synonym:
Translation
Position Chain Variation Link
10 10 c, g dbSNP:769124181
11 11 c, t dbSNP:201390690
13 13 c, t dbSNP:771265312
23 23 c, t dbSNP:776973617
40 40 -, c dbSNP:777893315
41 41 -, c dbSNP:747003629
45 45 c, t dbSNP:759676259
47 47 a, c dbSNP:765434483
48 48 a, g dbSNP:752732770
49 49 c, t dbSNP:376053501
54 54 a, g dbSNP:764160030
58 58 c, g dbSNP:369489910
63 63 c, t dbSNP:751518222
66 66 c, t dbSNP:757173865
67 67 c, g dbSNP:377714119
73 73 a, g dbSNP:750165021
84 84 a, t dbSNP:533438084
103 103 c, g dbSNP:779704639
110 110 c, t dbSNP:748777921
112 112 c, t dbSNP:768120530
116 116 a, t dbSNP:373252297
118 118 a, c dbSNP:376953387
121 121 c, t dbSNP:146255899
133 133 a, g dbSNP:370390772
137 137 a, g dbSNP:778394964
141 141 c, g dbSNP:747594090
142 142 a, c dbSNP:549336813
155 155 a, c dbSNP:757776150
158 158 a, t dbSNP:781688970
162 162 a, t dbSNP:746251686
167 167 c, t dbSNP:368374808
170 170 c, g dbSNP:770164638
175 175 a, g dbSNP:775631906
177 177 a, g dbSNP:749515368
186 186 c, t dbSNP:768932056
190 190 c, g dbSNP:774585627
194 194 c, t dbSNP:761930850
210 210 a, g dbSNP:374327609
211 211 c, t dbSNP:373980582
218 218 a, c dbSNP:200673897
218 218 -, c dbSNP:5828039
247 247 c, t dbSNP:766185433
254 254 c, g dbSNP:753556627
257 257 -, g dbSNP:776960175
277 277 c, t dbSNP:754633975
278 278 g, t dbSNP:200032614
283 283 c, t dbSNP:764815909
285 285 a, c dbSNP:752226731
288 288 a, g dbSNP:757886152
291 291 c, t dbSNP:781590969
293 293 c, t dbSNP:746365253
299 299 a, g dbSNP:553623075
300 300 c, t dbSNP:572205035
310 310 a, t dbSNP:749605519
312 312 c, t dbSNP:769017873
317 317 g, t dbSNP:774671566
320 320 c, t dbSNP:544581832
321 321 c, t dbSNP:748275762
322 322 a, g dbSNP:772167504
325 325 c, t dbSNP:773083486
327 327 a, g dbSNP:760660355
331 331 a, c dbSNP:766166052
332 332 a, g dbSNP:776428281
335 335 c, g dbSNP:759278208
336 336 a, g dbSNP:764901777
339 339 c, t dbSNP:752316852
341 341 c, g dbSNP:757897789
344 344 a, g dbSNP:546600885
345 345 a, c dbSNP:750965859
348 348 c, t dbSNP:756658001
349 349 c, g, t dbSNP:375765151
350 350 a, g dbSNP:755359679
355 355 c, t dbSNP:779324408
358 358 c, t dbSNP:748386545
363 363 c, t dbSNP:772112030
367 367 a, g dbSNP:777915948
373 373 c, t dbSNP:747006042
376 376 c, t dbSNP:770880969
377 377 c, t dbSNP:776511193
397 397 a, g dbSNP:267605475
400 400 c, t dbSNP:186303509
401 401 a, g dbSNP:71647811
409 409 c, t dbSNP:769556737
410 410 a, g dbSNP:758663865
416 416 -, t dbSNP:770120266
428 428 a, g dbSNP:777813964
430 430 c, t dbSNP:143468961
431 431 a, g dbSNP:770966935
437 437 a, t dbSNP:765205227
448 448 a, g dbSNP:113780398
451 451 -, agg dbSNP:775870175
452 452 -, g dbSNP:761454301
467 467 a, g dbSNP:745793784
473 473 a, g, t dbSNP:781246209
481 481 a, c dbSNP:756066182
483 483 a, t dbSNP:55741253
500 500 a, g dbSNP:749148035
510 510 a, g dbSNP:768310008
514 514 a, g dbSNP:774107458
536 536 c, t dbSNP:376907733
551 551 a, g dbSNP:771785908
573 573 g, t dbSNP:8107127
576 576 c, g dbSNP:760217365
580 580 a, c dbSNP:765809448
584 584 a, g dbSNP:775830225
600 600 c, t dbSNP:763424873
601 601 c, t dbSNP:115194365
604 604 c, g dbSNP:8106337
610 610 g, t dbSNP:757481580
622 622 g, t dbSNP:767676342
623 623 c, t dbSNP:750529359
637 637 g, t dbSNP:557730459
651 651 -, gcggt dbSNP:750107624
652 652 a, g dbSNP:756151698
661 661 -, gcggt dbSNP:786200899
673 673 -, c dbSNP:760040233
673 673 c, g, t dbSNP:780088167
674 674 c, g, t dbSNP:376905666
676 676 -, c dbSNP:786200902
676 676 c, t dbSNP:192624990
679 679 a, c dbSNP:771875570
681 681 a, c dbSNP:772960131
682 682 a, c dbSNP:746558629
692 692 c, g dbSNP:572869684
695 695 c, g dbSNP:770329421
707 707 c, t dbSNP:776126232
711 711 c, t dbSNP:1110627
712 712 a, g, t dbSNP:140489087
719 719 c, g, t dbSNP:200275281
720 720 a, g dbSNP:201901192
723 723 a, c dbSNP:762209881
726 726 g, t dbSNP:752593714
732 732 a, g dbSNP:35380611
735 735 c, g dbSNP:145191532
739 739 a, g dbSNP:760811405
741 741 a, g dbSNP:370258504
744 744 a, g dbSNP:753887634
761 761 a, g dbSNP:529420446
763 763 c, t dbSNP:551166419
770 770 c, t dbSNP:104894675
771 771 a, g dbSNP:373253569
783 783 a, g dbSNP:777709054
797 797 a, c dbSNP:751336041
805 805 a, g dbSNP:146906924
806 806 g, t dbSNP:780854675
809 809 c, t dbSNP:376715067
812 812 a, g dbSNP:201665383
813 813 g, t dbSNP:779449946
837 837 a, c dbSNP:748649010
840 840 -, g dbSNP:35667374
846 846 c, t dbSNP:772500636
847 847 a, g dbSNP:773579241
859 859 c, t dbSNP:374417033
861 861 c, t dbSNP:771091661
862 862 c, t dbSNP:776881747
863 863 a, g dbSNP:139297205
878 878 a, c, g dbSNP:765398793
893 893 a, g dbSNP:762991216
895 895 c, t dbSNP:200850430
896 896 a, g dbSNP:141774764
898 898 a, g dbSNP:147079724
903 903 c, t dbSNP:368487646
904 904 a, c, g dbSNP:372831253
906 906 g, t dbSNP:755687347
908 908 a, g, t dbSNP:779543693
912 912 a, g dbSNP:758925975
913 913 a, t dbSNP:199503695
917 917 a, g dbSNP:778215179
921 921 a, g dbSNP:747375666
936 936 a, c dbSNP:747538194
948 948 a, g dbSNP:757634002
954 954 c, t dbSNP:753915676
960 960 c, t dbSNP:781626135
961 961 a, g dbSNP:148016836
962 962 c, t dbSNP:538488581
963 963 a, g dbSNP:775820811
967 967 g, t dbSNP:749425668
970 970 c, t dbSNP:7249157
973 973 -, cgggctg dbSNP:778821687
973 973 c, t dbSNP:372702131
974 974 a, g dbSNP:774218328
977 977 c, t dbSNP:553945114
981 981 a, g dbSNP:141671275
988 988 a, g dbSNP:773079824
991 991 a, g dbSNP:760420806
994 994 c, t dbSNP:766060828
995 995 a, g dbSNP:572215947
997 997 a, g dbSNP:150100958
1003 1003 -, at dbSNP:786200900
1008 1008 c, g dbSNP:764800780
1014 1014 g, t dbSNP:752084828
1027 1027 a, c, t dbSNP:139638161
1028 1028 a, g dbSNP:750852974
1030 1030 c, t dbSNP:756522217
1031 1031 a, g dbSNP:780479340
1040 1040 g, t dbSNP:749513254
1042 1042 c, t dbSNP:138378695
1043 1043 a, g dbSNP:779062455
1048 1048 g, t dbSNP:748127891
1053 1053 a, c dbSNP:772075634
1061 1061 a, t dbSNP:772991073
1072 1072 c, g dbSNP:760514457
1087 1087 c, g, t dbSNP:2304214
1088 1088 a, c, g dbSNP:530857183
1094 1094 c, t dbSNP:752277223
1095 1095 a, g dbSNP:374501656
1098 1098 a, g dbSNP:762332887
1111 1111 c, g dbSNP:768115423
1114 1114 g, t dbSNP:376526613
1118 1118 g, t dbSNP:756610034
1124 1124 c, t dbSNP:146274789
1125 1125 a, g, t dbSNP:781119337
1129 1129 c, t dbSNP:755250115
1134 1134 c, t dbSNP:139372003
1143 1143 a, g dbSNP:748298755
1149 1149 a, g dbSNP:142597040
1153 1153 c, g dbSNP:768362076
1154 1154 a, g dbSNP:774019112
1157 1157 c, g dbSNP:761366581
1171 1171 g, t dbSNP:767031027
1181 1181 c, t dbSNP:777253263
1184 1184 c, t dbSNP:760004390
1194 1194 a, g dbSNP:786205519
1196 1196 c, t dbSNP:765517369
1201 1201 c, t dbSNP:367573123
1202 1202 a, g dbSNP:758562918
1210 1210 a, g dbSNP:115456333
1212 1212 a, g dbSNP:104894674
1218 1218 a, g dbSNP:751674309
1226 1226 c, t dbSNP:757298214
1228 1228 c, t dbSNP:781159181
1229 1229 a, c, g dbSNP:745786021
1231 1231 c, g dbSNP:779723472
1232 1232 c, t dbSNP:749059188
1234 1234 a, g dbSNP:765401126
1237 1237 c, t dbSNP:751604223
1243 1243 c, t dbSNP:778676863
1245 1245 c, t dbSNP:747708804
1246 1246 a, g dbSNP:771693899
1253 1253 a, g dbSNP:777263670
1259 1259 a, g dbSNP:759968231
1272 1272 c, t dbSNP:770278809
1273 1273 g, t dbSNP:537365183
1281 1281 a, g dbSNP:763267581
1292 1292 a, g dbSNP:764341764
1354 1354 a, c, g dbSNP:751762334
1359 1359 c, t dbSNP:767584523
1360 1360 c, t dbSNP:750457185
1365 1365 -, gacccgtgcgccgcgcg dbSNP:786200901
1365 1365 a, g dbSNP:199831437
1377 1377 a, c, t dbSNP:780000990
1378 1378 a, c dbSNP:577978350
1382 1382 g, t dbSNP:754798552
1391 1391 c, t dbSNP:778766365
1399 1399 c, t dbSNP:747799043
1404 1404 c, g dbSNP:771783907
1405 1405 c, t dbSNP:777164429
1407 1407 g, t dbSNP:746479806
1408 1408 c, t dbSNP:545167839
1412 1412 a, g dbSNP:776036444
1414 1414 c, t dbSNP:554268445
1420 1420 g, t dbSNP:768998068
1425 1425 c, t dbSNP:774627246
1428 1428 c, t dbSNP:762031444
1432 1432 c, t dbSNP:767726697
1433 1433 c, t dbSNP:750497851
1434 1434 a, t dbSNP:572290101
1436 1436 a, c, g, t dbSNP:766274162
1437 1437 a, t dbSNP:754886562
1442 1442 a, g dbSNP:182454962
1444 1444 g, t dbSNP:561167838
1446 1446 g, t dbSNP:758148689
1456 1456 a, c, t dbSNP:777442783
1459 1459 a, c dbSNP:756773286
1472 1472 c, g dbSNP:780488030
1474 1474 a, c dbSNP:187836169
1480 1480 c, g dbSNP:769089751
1488 1488 c, g dbSNP:774717171
1489 1489 c, t dbSNP:748469020
1492 1492 g, t dbSNP:772222188
1498 1498 -, g dbSNP:786200903
1499 1499 c, g dbSNP:773460228
1501 1501 c, g dbSNP:760723858
1502 1502 a, g dbSNP:766475458
1503 1503 g, t dbSNP:531838368
1511 1511 c, t dbSNP:776786479
1513 1513 c, t dbSNP:759560622
1514 1514 a, g dbSNP:368229699
1516 1516 g, t dbSNP:765219149
1519 1519 a, c, g dbSNP:752572755
1523 1523 a, c dbSNP:763704620
1524 1524 a, g dbSNP:751216323
1528 1528 a, c, g, t dbSNP:756788459
1532 1532 c, g dbSNP:767423604
1534 1534 g, t dbSNP:779358433
1541 1541 c, t dbSNP:201354924
1542 1542 c, t dbSNP:750189228
1545 1545 c, t dbSNP:773373873
1554 1554 g, t dbSNP:747258899
1556 1556 -, c dbSNP:781379219
1556 1556 c, t dbSNP:369634266
1558 1558 c, t dbSNP:776872996
1569 1569 a, g dbSNP:104894676
1571 1571 a, g dbSNP:111556824
1579 1579 c, t dbSNP:765306971
1583 1583 a, g dbSNP:775548960
1584 1584 c, t dbSNP:762718624
1585 1585 a, g dbSNP:763949120
1590 1590 g, t dbSNP:543714737
1593 1593 a, t dbSNP:761545310
1600 1600 -, c dbSNP:746341065
1605 1605 g, t dbSNP:14635
1609 1609 c, t dbSNP:767114247
1610 1610 a, c dbSNP:749973172
1617 1617 a, t dbSNP:755597448
1619 1619 a, t dbSNP:779452017
1620 1620 c, t dbSNP:191149379
1639 1639 c, t dbSNP:376283152
1643 1643 c, t dbSNP:1055331
1644 1644 g, t dbSNP:747287917
1648 1648 a, t dbSNP:771217320
1653 1653 c, g dbSNP:781534390
1663 1663 a, g dbSNP:745997530
1668 1668 c, t dbSNP:369266504
1678 1678 c, t dbSNP:775640643
1680 1680 c, t dbSNP:547155681
1681 1681 a, g dbSNP:200988915
1687 1687 a, g dbSNP:774229336
1696 1696 c, t dbSNP:761480287
1705 1705 g, t dbSNP:568745157
1707 1707 a, g dbSNP:767204028
1709 1709 a, c, g dbSNP:750062182
1719 1719 a, g dbSNP:748859565
1722 1722 -, a dbSNP:770355531
1734 1734 a, c dbSNP:771849483
1735 1735 a, g dbSNP:772924663
1739 1739 a, g dbSNP:577591982
1741 1741 a, t dbSNP:754576543
1752 1752 a, g dbSNP:765968413
1787 1787 a, g dbSNP:144011919
1793 1793 g, t dbSNP:758939727
1796 1796 c, t dbSNP:145264173
1802 1802 a, g dbSNP:751999027
1806 1806 -, ac dbSNP:772701329
1807 1807 c, t dbSNP:757766484
1809 1809 c, g dbSNP:768002373
1810 1810 c, t dbSNP:750763232
1811 1811 c, g, t dbSNP:371433358
1812 1812 c, g dbSNP:749430803
1824 1824 a, g dbSNP:758451349
1825 1825 c, t dbSNP:777747942
1830 1830 c, g dbSNP:751496025
1839 1839 a, g dbSNP:757153999
1854 1854 g, t dbSNP:780866206
1855 1855 c, t dbSNP:745631235
1860 1860 a, g dbSNP:200982994
1865 1865 c, t dbSNP:779826940
1907 1907 g, t dbSNP:1055148
1989 1989 c, t dbSNP:778133456
1992 1992 c, t dbSNP:531758419
2013 2013 a, t dbSNP:73551869
2024 2024 c, t dbSNP:747450923

Target ORF information:

RefSeq Version NM_203486
Organism Homo sapiens (human)
Definition Homo sapiens delta-like 3 (Drosophila) (DLL3), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_203486

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGTCTCCC CACGGATGTC CGGGCTCCTC TCCCAGACTG TGATCCTAGC GCTCATTTTC 
CTCCCCCAGA CACGGCCCGC TGGCGTCTTC GAGCTGCAGA TCCACTCTTT CGGGCCGGGT
CCAGGCCCTG GGGCCCCGCG GTCCCCCTGC AGCGCCCGGC TCCCCTGCCG CCTCTTCTTC
AGAGTCTGCC TGAAGCCTGG GCTCTCAGAG GAGGCCGCCG AGTCCCCGTG CGCCCTGGGC
GCGGCGCTGA GTGCGCGCGG ACCGGTCTAC ACCGAGCAGC CCGGAGCGCC CGCGCCTGAT
CTCCCACTGC CCGACGGCCT CTTGCAGGTG CCCTTCCGGG ACGCCTGGCC TGGCACCTTC
TCTTTCATCA TCGAAACCTG GAGAGAGGAG TTAGGAGACC AGATTGGAGG GCCCGCCTGG
AGCCTGCTGG CGCGCGTGGC TGGCAGGCGG CGCTTGGCAG CCGGAGGCCC GTGGGCCCGG
GACATTCAGC GCGCAGGCGC CTGGGAGCTG CGCTTCTCGT ACCGCGCGCG CTGCGAGCCG
CCTGCCGTCG GGACCGCGTG CACGCGCCTC TGCCGTCCGC GCAGCGCCCC CTCGCGGTGC
GGTCCGGGAC TGCGCCCCTG CGCACCGCTC GAGGACGAAT GTGAGGCGCC GCTGGTGTGC
CGAGCAGGCT GCAGCCCTGA GCATGGCTTC TGTGAACAGC CCGGTGAATG CCGATGCCTA
GAGGGCTGGA CTGGACCCCT CTGCACGGTC CCTGTCTCCA CCAGCAGCTG CCTCAGCCCC
AGGGGCCCGT CCTCTGCTAC CACCGGATGC CTTGTCCCTG GGCCTGGGCC CTGTGACGGG
AACCCGTGTG CCAATGGAGG CAGCTGTAGT GAGACACCCA GGTCCTTTGA ATGCACCTGC
CCGCGTGGGT TCTACGGGCT GCGGTGTGAG GTGAGCGGGG TGACATGTGC AGATGGACCC
TGCTTCAACG GCGGCTTGTG TGTCGGGGGT GCAGACCCTG ACTCTGCCTA CATCTGCCAC
TGCCCACCCG GTTTCCAAGG CTCCAACTGT GAGAAGAGGG TGGACCGGTG CAGCCTGCAG
CCATGCCGCA ATGGCGGACT CTGCCTGGAC CTGGGCCACG CCCTGCGCTG CCGCTGCCGC
GCCGGCTTCG CGGGTCCTCG CTGCGAGCAC GACCTGGACG ACTGCGCGGG CCGCGCCTGC
GCTAACGGCG GCACGTGTGT GGAGGGCGGC GGCGCGCACC GCTGCTCCTG CGCGCTGGGC
TTCGGCGGCC GCGACTGCCG CGAGCGCGCG GACCCGTGCG CCGCGCGCCC CTGTGCTCAC
GGCGGCCGCT GCTACGCCCA CTTCTCCGGC CTCGTCTGCG CTTGCGCTCC CGGCTACATG
GGAGCGCGGT GTGAGTTCCC AGTGCACCCC GACGGCGCAA GCGCCTTGCC CGCGGCCCCG
CCGGGCCTCA GGCCCGGGGA CCCTCAGCGC TACCTTTTGC CTCCGGCTCT GGGACTGCTC
GTGGCCGCGG GCGTGGCCGG CGCTGCGCTC TTGCTGGTCC ACGTGCGCCG CCGTGGCCAC
TCCCAGGATG CTGGGTCTCG CTTGCTGGCT GGGACCCCGG AGCCGTCAGT CCACGCACTC
CCGGATGCAC TCAACAACCT AAGGACGCAG GAGGGTTCCG GGGATGGTCC GAGCTCGTCC
GTAGATTGGA ATCGCCCTGA AGATGTAGAC CCTCAAGGGA TTTATGTCAT ATCTGCTCCT
TCCATCTACG CTCGGGAGGC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26149
Accession Version NM_016941.3
Sequence Information ORF Nucleotide Sequence (Length: 1857bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product delta-like protein 3 isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB035825.1, BC000218.2 and AA865362.1. This sequence is a reference standard in the RefSeqGene project. On May 29, 2008 this sequence version replaced gi:45243550. Summary: This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC000218.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGGTCTCCC CACGGATGTC CGGGCTCCTC TCCCAGACTG TGATCCTAGC GCTCATTTTC 
CTCCCCCAGA CACGGCCCGC TGGCGTCTTC GAGCTGCAGA TCCACTCTTT CGGGCCGGGT
CCAGGCCCTG GGGCCCCGCG GTCCCCCTGC AGCGCCCGGC TCCCCTGCCG CCTCTTCTTC
AGAGTCTGCC TGAAGCCTGG GCTCTCAGAG GAGGCCGCCG AGTCCCCGTG CGCCCTGGGC
GCGGCGCTGA GTGCGCGCGG ACCGGTCTAC ACCGAGCAGC CCGGAGCGCC CGCGCCTGAT
CTCCCACTGC CCGACGGCCT CTTGCAGGTG CCCTTCCGGG ACGCCTGGCC TGGCACCTTC
TCTTTCATCA TCGAAACCTG GAGAGAGGAG TTAGGAGACC AGATTGGAGG GCCCGCCTGG
AGCCTGCTGG CGCGCGTGGC TGGCAGGCGG CGCTTGGCAG CCGGAGGCCC GTGGGCCCGG
GACATTCAGC GCGCAGGCGC CTGGGAGCTG CGCTTCTCGT ACCGCGCGCG CTGCGAGCCG
CCTGCCGTCG GGACCGCGTG CACGCGCCTC TGCCGTCCGC GCAGCGCCCC CTCGCGGTGC
GGTCCGGGAC TGCGCCCCTG CGCACCGCTC GAGGACGAAT GTGAGGCGCC GCTGGTGTGC
CGAGCAGGCT GCAGCCCTGA GCATGGCTTC TGTGAACAGC CCGGTGAATG CCGATGCCTA
GAGGGCTGGA CTGGACCCCT CTGCACGGTC CCTGTCTCCA CCAGCAGCTG CCTCAGCCCC
AGGGGCCCGT CCTCTGCTAC CACCGGATGC CTTGTCCCTG GGCCTGGGCC CTGTGACGGG
AACCCGTGTG CCAATGGAGG CAGCTGTAGT GAGACACCCA GGTCCTTTGA ATGCACCTGC
CCGCGTGGGT TCTACGGGCT GCGGTGTGAG GTGAGCGGGG TGACATGTGC AGATGGACCC
TGCTTCAACG GCGGCTTGTG TGTCGGGGGT GCAGACCCTG ACTCTGCCTA CATCTGCCAC
TGCCCACCCG GTTTCCAAGG CTCCAACTGT GAGAAGAGGG TGGACCGGTG CAGCCTGCAG
CCATGCCGCA ATGGCGGACT CTGCCTGGAC CTGGGCCACG CCCTGCGCTG CCGCTGCCGC
GCCGGCTTCG CGGGTCCTCG CTGCGAGCAC GACCTGGACG ACTGCGCGGG CCGCGCCTGC
GCTAACGGCG GCACGTGTGT GGAGGGCGGC GGCGCGCACC GCTGCTCCTG CGCGCTGGGC
TTCGGCGGCC GCGACTGCCG CGAGCGCGCG GACCCGTGCG CCGCGCGCCC CTGTGCTCAC
GGCGGCCGCT GCTACGCCCA CTTCTCCGGC CTCGTCTGCG CTTGCGCTCC CGGCTACATG
GGAGCGCGGT GTGAGTTCCC AGTGCACCCC GACGGCGCAA GCGCCTTGCC CGCGGCCCCG
CCGGGCCTCA GGCCCGGGGA CCCTCAGCGC TACCTTTTGC CTCCGGCTCT GGGACTGCTC
GTGGCCGCGG GCGTGGCCGG CGCTGCGCTC TTGCTGGTCC ACGTGCGCCG CCGTGGCCAC
TCCCAGGATG CTGGGTCTCG CTTGCTGGCT GGGACCCCGG AGCCGTCAGT CCACGCACTC
CCGGATGCAC TCAACAACCT AAGGACGCAG GAGGGTTCCG GGGATGGTCC GAGCTCGTCC
GTAGATTGGA ATCGCCCTGA AGATGTAGAC CCTCAAGGGA TTTATGTCAT ATCTGCTCCT
TCCATCTACG CTCGGGAGGT AGCGACGCCC CTTTTCCCCC CGCTACACAC TGGGCGCGCT
GGGCAGAGGC AGCACCTGCT TTTTCCCTAC CCTTCCTCGA TTCTGTCCGT GAAATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_058637.1
CDS59..1915
Misc Feature(1)134..343(+)
Misc Feature(2)530..802(+)
Misc Feature(3)893..988(+)
Misc Feature(4)1004..1111(+)
Misc Feature(5)1118..1225(+)
Misc Feature(6)1124..1168(+)
Misc Feature(7)1229..1336(+)
Misc Feature(8)1229..1282(+)
Misc Feature(9)1535..1597(+)
Exon (1)1..127
Gene:DLL3
Gene Synonym:
Exon (2)128..409
Gene:DLL3
Gene Synonym:
Exon (3)410..467
Gene:DLL3
Gene Synonym:
Exon (4)468..710
Gene:DLL3
Gene Synonym:
Exon (5)711..928
Gene:DLL3
Gene Synonym:
Exon (6)929..1151
Gene:DLL3
Gene Synonym:
Exon (7)1152..1731
Gene:DLL3
Gene Synonym:
Exon (8)1732..2383
Gene:DLL3
Gene Synonym:
Translation
Position Chain Variation Link
10 10 c, g dbSNP:769124181
11 11 c, t dbSNP:201390690
13 13 c, t dbSNP:771265312
23 23 c, t dbSNP:776973617
40 40 -, c dbSNP:777893315
41 41 -, c dbSNP:747003629
45 45 c, t dbSNP:759676259
47 47 a, c dbSNP:765434483
48 48 a, g dbSNP:752732770
49 49 c, t dbSNP:376053501
54 54 a, g dbSNP:764160030
58 58 c, g dbSNP:369489910
63 63 c, t dbSNP:751518222
66 66 c, t dbSNP:757173865
67 67 c, g dbSNP:377714119
73 73 a, g dbSNP:750165021
84 84 a, t dbSNP:533438084
103 103 c, g dbSNP:779704639
110 110 c, t dbSNP:748777921
112 112 c, t dbSNP:768120530
116 116 a, t dbSNP:373252297
118 118 a, c dbSNP:376953387
121 121 c, t dbSNP:146255899
133 133 a, g dbSNP:370390772
137 137 a, g dbSNP:778394964
141 141 c, g dbSNP:747594090
142 142 a, c dbSNP:549336813
155 155 a, c dbSNP:757776150
158 158 a, t dbSNP:781688970
162 162 a, t dbSNP:746251686
167 167 c, t dbSNP:368374808
170 170 c, g dbSNP:770164638
175 175 a, g dbSNP:775631906
177 177 a, g dbSNP:749515368
186 186 c, t dbSNP:768932056
190 190 c, g dbSNP:774585627
194 194 c, t dbSNP:761930850
210 210 a, g dbSNP:374327609
211 211 c, t dbSNP:373980582
218 218 a, c dbSNP:200673897
218 218 -, c dbSNP:5828039
247 247 c, t dbSNP:766185433
254 254 c, g dbSNP:753556627
257 257 -, g dbSNP:776960175
277 277 c, t dbSNP:754633975
278 278 g, t dbSNP:200032614
283 283 c, t dbSNP:764815909
285 285 a, c dbSNP:752226731
288 288 a, g dbSNP:757886152
291 291 c, t dbSNP:781590969
293 293 c, t dbSNP:746365253
299 299 a, g dbSNP:553623075
300 300 c, t dbSNP:572205035
310 310 a, t dbSNP:749605519
312 312 c, t dbSNP:769017873
317 317 g, t dbSNP:774671566
320 320 c, t dbSNP:544581832
321 321 c, t dbSNP:748275762
322 322 a, g dbSNP:772167504
325 325 c, t dbSNP:773083486
327 327 a, g dbSNP:760660355
331 331 a, c dbSNP:766166052
332 332 a, g dbSNP:776428281
335 335 c, g dbSNP:759278208
336 336 a, g dbSNP:764901777
339 339 c, t dbSNP:752316852
341 341 c, g dbSNP:757897789
344 344 a, g dbSNP:546600885
345 345 a, c dbSNP:750965859
348 348 c, t dbSNP:756658001
349 349 c, g, t dbSNP:375765151
350 350 a, g dbSNP:755359679
355 355 c, t dbSNP:779324408
358 358 c, t dbSNP:748386545
363 363 c, t dbSNP:772112030
367 367 a, g dbSNP:777915948
373 373 c, t dbSNP:747006042
376 376 c, t dbSNP:770880969
377 377 c, t dbSNP:776511193
397 397 a, g dbSNP:267605475
400 400 c, t dbSNP:186303509
401 401 a, g dbSNP:71647811
409 409 c, t dbSNP:769556737
410 410 a, g dbSNP:758663865
416 416 -, t dbSNP:770120266
428 428 a, g dbSNP:777813964
430 430 c, t dbSNP:143468961
431 431 a, g dbSNP:770966935
437 437 a, t dbSNP:765205227
448 448 a, g dbSNP:113780398
451 451 -, agg dbSNP:775870175
452 452 -, g dbSNP:761454301
467 467 a, g dbSNP:745793784
473 473 a, g, t dbSNP:781246209
481 481 a, c dbSNP:756066182
483 483 a, t dbSNP:55741253
500 500 a, g dbSNP:749148035
510 510 a, g dbSNP:768310008
514 514 a, g dbSNP:774107458
536 536 c, t dbSNP:376907733
551 551 a, g dbSNP:771785908
573 573 g, t dbSNP:8107127
576 576 c, g dbSNP:760217365
580 580 a, c dbSNP:765809448
584 584 a, g dbSNP:775830225
600 600 c, t dbSNP:763424873
601 601 c, t dbSNP:115194365
604 604 c, g dbSNP:8106337
610 610 g, t dbSNP:757481580
622 622 g, t dbSNP:767676342
623 623 c, t dbSNP:750529359
637 637 g, t dbSNP:557730459
651 651 -, gcggt dbSNP:750107624
652 652 a, g dbSNP:756151698
661 661 -, gcggt dbSNP:786200899
673 673 -, c dbSNP:760040233
673 673 c, g, t dbSNP:780088167
674 674 c, g, t dbSNP:376905666
676 676 -, c dbSNP:786200902
676 676 c, t dbSNP:192624990
679 679 a, c dbSNP:771875570
681 681 a, c dbSNP:772960131
682 682 a, c dbSNP:746558629
692 692 c, g dbSNP:572869684
695 695 c, g dbSNP:770329421
707 707 c, t dbSNP:776126232
711 711 c, t dbSNP:1110627
712 712 a, g, t dbSNP:140489087
719 719 c, g, t dbSNP:200275281
720 720 a, g dbSNP:201901192
723 723 a, c dbSNP:762209881
726 726 g, t dbSNP:752593714
732 732 a, g dbSNP:35380611
735 735 c, g dbSNP:145191532
739 739 a, g dbSNP:760811405
741 741 a, g dbSNP:370258504
744 744 a, g dbSNP:753887634
761 761 a, g dbSNP:529420446
763 763 c, t dbSNP:551166419
770 770 c, t dbSNP:104894675
771 771 a, g dbSNP:373253569
783 783 a, g dbSNP:777709054
797 797 a, c dbSNP:751336041
805 805 a, g dbSNP:146906924
806 806 g, t dbSNP:780854675
809 809 c, t dbSNP:376715067
812 812 a, g dbSNP:201665383
813 813 g, t dbSNP:779449946
837 837 a, c dbSNP:748649010
840 840 -, g dbSNP:35667374
846 846 c, t dbSNP:772500636
847 847 a, g dbSNP:773579241
859 859 c, t dbSNP:374417033
861 861 c, t dbSNP:771091661
862 862 c, t dbSNP:776881747
863 863 a, g dbSNP:139297205
878 878 a, c, g dbSNP:765398793
893 893 a, g dbSNP:762991216
895 895 c, t dbSNP:200850430
896 896 a, g dbSNP:141774764
898 898 a, g dbSNP:147079724
903 903 c, t dbSNP:368487646
904 904 a, c, g dbSNP:372831253
906 906 g, t dbSNP:755687347
908 908 a, g, t dbSNP:779543693
912 912 a, g dbSNP:758925975
913 913 a, t dbSNP:199503695
917 917 a, g dbSNP:778215179
921 921 a, g dbSNP:747375666
936 936 a, c dbSNP:747538194
948 948 a, g dbSNP:757634002
954 954 c, t dbSNP:753915676
960 960 c, t dbSNP:781626135
961 961 a, g dbSNP:148016836
962 962 c, t dbSNP:538488581
963 963 a, g dbSNP:775820811
967 967 g, t dbSNP:749425668
970 970 c, t dbSNP:7249157
973 973 -, cgggctg dbSNP:778821687
973 973 c, t dbSNP:372702131
974 974 a, g dbSNP:774218328
977 977 c, t dbSNP:553945114
981 981 a, g dbSNP:141671275
988 988 a, g dbSNP:773079824
991 991 a, g dbSNP:760420806
994 994 c, t dbSNP:766060828
995 995 a, g dbSNP:572215947
997 997 a, g dbSNP:150100958
1003 1003 -, at dbSNP:786200900
1008 1008 c, g dbSNP:764800780
1014 1014 g, t dbSNP:752084828
1027 1027 a, c, t dbSNP:139638161
1028 1028 a, g dbSNP:750852974
1030 1030 c, t dbSNP:756522217
1031 1031 a, g dbSNP:780479340
1040 1040 g, t dbSNP:749513254
1042 1042 c, t dbSNP:138378695
1043 1043 a, g dbSNP:779062455
1048 1048 g, t dbSNP:748127891
1053 1053 a, c dbSNP:772075634
1061 1061 a, t dbSNP:772991073
1072 1072 c, g dbSNP:760514457
1087 1087 c, g, t dbSNP:2304214
1088 1088 a, c, g dbSNP:530857183
1094 1094 c, t dbSNP:752277223
1095 1095 a, g dbSNP:374501656
1098 1098 a, g dbSNP:762332887
1111 1111 c, g dbSNP:768115423
1114 1114 g, t dbSNP:376526613
1118 1118 g, t dbSNP:756610034
1124 1124 c, t dbSNP:146274789
1125 1125 a, g, t dbSNP:781119337
1129 1129 c, t dbSNP:755250115
1134 1134 c, t dbSNP:139372003
1143 1143 a, g dbSNP:748298755
1149 1149 a, g dbSNP:142597040
1153 1153 c, g dbSNP:768362076
1154 1154 a, g dbSNP:774019112
1157 1157 c, g dbSNP:761366581
1171 1171 g, t dbSNP:767031027
1181 1181 c, t dbSNP:777253263
1184 1184 c, t dbSNP:760004390
1194 1194 a, g dbSNP:786205519
1196 1196 c, t dbSNP:765517369
1201 1201 c, t dbSNP:367573123
1202 1202 a, g dbSNP:758562918
1210 1210 a, g dbSNP:115456333
1212 1212 a, g dbSNP:104894674
1218 1218 a, g dbSNP:751674309
1226 1226 c, t dbSNP:757298214
1228 1228 c, t dbSNP:781159181
1229 1229 a, c, g dbSNP:745786021
1231 1231 c, g dbSNP:779723472
1232 1232 c, t dbSNP:749059188
1234 1234 a, g dbSNP:765401126
1237 1237 c, t dbSNP:751604223
1243 1243 c, t dbSNP:778676863
1245 1245 c, t dbSNP:747708804
1246 1246 a, g dbSNP:771693899
1253 1253 a, g dbSNP:777263670
1259 1259 a, g dbSNP:759968231
1272 1272 c, t dbSNP:770278809
1273 1273 g, t dbSNP:537365183
1281 1281 a, g dbSNP:763267581
1292 1292 a, g dbSNP:764341764
1354 1354 a, c, g dbSNP:751762334
1359 1359 c, t dbSNP:767584523
1360 1360 c, t dbSNP:750457185
1365 1365 -, gacccgtgcgccgcgcg dbSNP:786200901
1365 1365 a, g dbSNP:199831437
1377 1377 a, c, t dbSNP:780000990
1378 1378 a, c dbSNP:577978350
1382 1382 g, t dbSNP:754798552
1391 1391 c, t dbSNP:778766365
1399 1399 c, t dbSNP:747799043
1404 1404 c, g dbSNP:771783907
1405 1405 c, t dbSNP:777164429
1407 1407 g, t dbSNP:746479806
1408 1408 c, t dbSNP:545167839
1412 1412 a, g dbSNP:776036444
1414 1414 c, t dbSNP:554268445
1420 1420 g, t dbSNP:768998068
1425 1425 c, t dbSNP:774627246
1428 1428 c, t dbSNP:762031444
1432 1432 c, t dbSNP:767726697
1433 1433 c, t dbSNP:750497851
1434 1434 a, t dbSNP:572290101
1436 1436 a, c, g, t dbSNP:766274162
1437 1437 a, t dbSNP:754886562
1442 1442 a, g dbSNP:182454962
1444 1444 g, t dbSNP:561167838
1446 1446 g, t dbSNP:758148689
1456 1456 a, c, t dbSNP:777442783
1459 1459 a, c dbSNP:756773286
1472 1472 c, g dbSNP:780488030
1474 1474 a, c dbSNP:187836169
1480 1480 c, g dbSNP:769089751
1488 1488 c, g dbSNP:774717171
1489 1489 c, t dbSNP:748469020
1492 1492 g, t dbSNP:772222188
1498 1498 -, g dbSNP:786200903
1499 1499 c, g dbSNP:773460228
1501 1501 c, g dbSNP:760723858
1502 1502 a, g dbSNP:766475458
1503 1503 g, t dbSNP:531838368
1511 1511 c, t dbSNP:776786479
1513 1513 c, t dbSNP:759560622
1514 1514 a, g dbSNP:368229699
1516 1516 g, t dbSNP:765219149
1519 1519 a, c, g dbSNP:752572755
1523 1523 a, c dbSNP:763704620
1524 1524 a, g dbSNP:751216323
1528 1528 a, c, g, t dbSNP:756788459
1532 1532 c, g dbSNP:767423604
1534 1534 g, t dbSNP:779358433
1541 1541 c, t dbSNP:201354924
1542 1542 c, t dbSNP:750189228
1545 1545 c, t dbSNP:773373873
1554 1554 g, t dbSNP:747258899
1556 1556 -, c dbSNP:781379219
1556 1556 c, t dbSNP:369634266
1558 1558 c, t dbSNP:776872996
1569 1569 a, g dbSNP:104894676
1571 1571 a, g dbSNP:111556824
1579 1579 c, t dbSNP:765306971
1583 1583 a, g dbSNP:775548960
1584 1584 c, t dbSNP:762718624
1585 1585 a, g dbSNP:763949120
1590 1590 g, t dbSNP:543714737
1593 1593 a, t dbSNP:761545310
1600 1600 -, c dbSNP:746341065
1605 1605 g, t dbSNP:14635
1609 1609 c, t dbSNP:767114247
1610 1610 a, c dbSNP:749973172
1617 1617 a, t dbSNP:755597448
1619 1619 a, t dbSNP:779452017
1620 1620 c, t dbSNP:191149379
1639 1639 c, t dbSNP:376283152
1643 1643 c, t dbSNP:1055331
1644 1644 g, t dbSNP:747287917
1648 1648 a, t dbSNP:771217320
1653 1653 c, g dbSNP:781534390
1663 1663 a, g dbSNP:745997530
1668 1668 c, t dbSNP:369266504
1678 1678 c, t dbSNP:775640643
1680 1680 c, t dbSNP:547155681
1681 1681 a, g dbSNP:200988915
1687 1687 a, g dbSNP:774229336
1696 1696 c, t dbSNP:761480287
1705 1705 g, t dbSNP:568745157
1707 1707 a, g dbSNP:767204028
1709 1709 a, c, g dbSNP:750062182
1719 1719 a, g dbSNP:748859565
1722 1722 -, a dbSNP:770355531
1734 1734 a, c dbSNP:771849483
1735 1735 a, g dbSNP:772924663
1739 1739 a, g dbSNP:577591982
1741 1741 a, t dbSNP:754576543
1752 1752 a, g dbSNP:765968413
1787 1787 a, g dbSNP:144011919
1793 1793 g, t dbSNP:758939727
1796 1796 c, t dbSNP:145264173
1802 1802 a, g dbSNP:751999027
1806 1806 -, ac dbSNP:772701329
1807 1807 c, t dbSNP:757766484
1809 1809 c, g dbSNP:768002373
1810 1810 c, t dbSNP:750763232
1811 1811 c, g, t dbSNP:371433358
1812 1812 c, g dbSNP:749430803
1818 1818 c, t dbSNP:754997290
1821 1821 a, c dbSNP:778974437
1823 1823 a, g dbSNP:748080617
1825 1825 g, t dbSNP:771937712
1828 1828 c, t dbSNP:267605476
1829 1829 -, t dbSNP:760398713
1833 1833 -, c dbSNP:765785746
1834 1834 -, c dbSNP:776323833
1834 1834 c, t dbSNP:773012836
1836 1836 c, g dbSNP:778339882
1837 1837 c, g, t dbSNP:770611082
1838 1838 c, g dbSNP:550561051
1843 1843 a, g dbSNP:199745659
1861 1861 a, g dbSNP:759145657
1863 1863 -, ag dbSNP:759531850
1864 1864 a, g dbSNP:200183802
1871 1871 c, t dbSNP:764651686
1873 1873 c, t dbSNP:147582946
1876 1876 g, t dbSNP:543757649
1877 1877 c, t dbSNP:151052276
1879 1879 g, t dbSNP:750855068
1884 1884 c, t dbSNP:756522236
1888 1888 -, c dbSNP:765903171
1888 1888 c, t dbSNP:766679747
1889 1889 a, c, g dbSNP:754000867
1890 1890 c, t dbSNP:778871834
1891 1891 c, t dbSNP:748176684
1896 1896 c, t dbSNP:758363118
1897 1897 c, g dbSNP:777658037
1903 1903 a, c, g dbSNP:746856386
1905 1905 a, c dbSNP:776415255
1906 1906 c, t dbSNP:140715276
1907 1907 a, g, t dbSNP:368772580
1912 1912 a, g dbSNP:774889509
1914 1914 g, t dbSNP:762517319
1919 1919 -, g dbSNP:752685181
1930 1930 c, t dbSNP:201994238
1956 1956 -, ttc dbSNP:758226555
1958 1958 a, c, t dbSNP:374551752
2003 2003 a, c dbSNP:576748683
2033 2033 c, t dbSNP:772533182
2057 2057 g, t dbSNP:569619393
2070 2070 a, c dbSNP:559109825
2092 2092 c, t dbSNP:367794721
2101 2101 a, g dbSNP:762786941
2105 2105 -, ga dbSNP:763967582
2110 2110 -, agagggg dbSNP:751705871
2112 2112 a, g dbSNP:766655092
2116 2116 c, g dbSNP:754172178
2123 2123 c, g dbSNP:200669115
2124 2124 c, t dbSNP:765459212
2128 2128 -, t dbSNP:558083766
2138 2138 c, t dbSNP:752815280
2150 2150 -, ctaggc dbSNP:759482385
2161 2161 a, g dbSNP:758451349
2162 2162 c, t dbSNP:777747942
2167 2167 c, g dbSNP:751496025
2176 2176 a, g dbSNP:757153999
2191 2191 g, t dbSNP:780866206
2192 2192 c, t dbSNP:745631235
2197 2197 a, g dbSNP:200982994
2202 2202 c, t dbSNP:779826940
2244 2244 g, t dbSNP:1055148
2326 2326 c, t dbSNP:778133456
2329 2329 c, t dbSNP:531758419
2350 2350 a, t dbSNP:73551869
2361 2361 c, t dbSNP:747450923

Target ORF information:

RefSeq Version NM_016941
Organism Homo sapiens (human)
Definition Homo sapiens delta-like 3 (Drosophila) (DLL3), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_016941

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGGTCTCCC CACGGATGTC CGGGCTCCTC TCCCAGACTG TGATCCTAGC GCTCATTTTC 
CTCCCCCAGA CACGGCCCGC TGGCGTCTTC GAGCTGCAGA TCCACTCTTT CGGGCCGGGT
CCAGGCCCTG GGGCCCCGCG GTCCCCCTGC AGCGCCCGGC TCCCCTGCCG CCTCTTCTTC
AGAGTCTGCC TGAAGCCTGG GCTCTCAGAG GAGGCCGCCG AGTCCCCGTG CGCCCTGGGC
GCGGCGCTGA GTGCGCGCGG ACCGGTCTAC ACCGAGCAGC CCGGAGCGCC CGCGCCTGAT
CTCCCACTGC CCGACGGCCT CTTGCAGGTG CCCTTCCGGG ACGCCTGGCC TGGCACCTTC
TCTTTCATCA TCGAAACCTG GAGAGAGGAG TTAGGAGACC AGATTGGAGG GCCCGCCTGG
AGCCTGCTGG CGCGCGTGGC TGGCAGGCGG CGCTTGGCAG CCGGAGGCCC GTGGGCCCGG
GACATTCAGC GCGCAGGCGC CTGGGAGCTG CGCTTCTCGT ACCGCGCGCG CTGCGAGCCG
CCTGCCGTCG GGACCGCGTG CACGCGCCTC TGCCGTCCGC GCAGCGCCCC CTCGCGGTGC
GGTCCGGGAC TGCGCCCCTG CGCACCGCTC GAGGACGAAT GTGAGGCGCC GCTGGTGTGC
CGAGCAGGCT GCAGCCCTGA GCATGGCTTC TGTGAACAGC CCGGTGAATG CCGATGCCTA
GAGGGCTGGA CTGGACCCCT CTGCACGGTC CCTGTCTCCA CCAGCAGCTG CCTCAGCCCC
AGGGGCCCGT CCTCTGCTAC CACCGGATGC CTTGTCCCTG GGCCTGGGCC CTGTGACGGG
AACCCGTGTG CCAATGGAGG CAGCTGTAGT GAGACACCCA GGTCCTTTGA ATGCACCTGC
CCGCGTGGGT TCTACGGGCT GCGGTGTGAG GTGAGCGGGG TGACATGTGC AGATGGACCC
TGCTTCAACG GCGGCTTGTG TGTCGGGGGT GCAGACCCTG ACTCTGCCTA CATCTGCCAC
TGCCCACCCG GTTTCCAAGG CTCCAACTGT GAGAAGAGGG TGGACCGGTG CAGCCTGCAG
CCATGCCGCA ATGGCGGACT CTGCCTGGAC CTGGGCCACG CCCTGCGCTG CCGCTGCCGC
GCCGGCTTCG CGGGTCCTCG CTGCGAGCAC GACCTGGACG ACTGCGCGGG CCGCGCCTGC
GCTAACGGCG GCACGTGTGT GGAGGGCGGC GGCGCGCACC GCTGCTCCTG CGCGCTGGGC
TTCGGCGGCC GCGACTGCCG CGAGCGCGCG GACCCGTGCG CCGCGCGCCC CTGTGCTCAC
GGCGGCCGCT GCTACGCCCA CTTCTCCGGC CTCGTCTGCG CTTGCGCTCC CGGCTACATG
GGAGCGCGGT GTGAGTTCCC AGTGCACCCC GACGGCGCAA GCGCCTTGCC CGCGGCCCCG
CCGGGCCTCA GGCCCGGGGA CCCTCAGCGC TACCTTTTGC CTCCGGCTCT GGGACTGCTC
GTGGCCGCGG GCGTGGCCGG CGCTGCGCTC TTGCTGGTCC ACGTGCGCCG CCGTGGCCAC
TCCCAGGATG CTGGGTCTCG CTTGCTGGCT GGGACCCCGG AGCCGTCAGT CCACGCACTC
CCGGATGCAC TCAACAACCT AAGGACGCAG GAGGGTTCCG GGGATGGTCC GAGCTCGTCC
GTAGATTGGA ATCGCCCTGA AGATGTAGAC CCTCAAGGGA TTTATGTCAT ATCTGCTCCT
TCCATCTACG CTCGGGAGGT AGCGACGCCC CTTTTCCCCC CGCTACACAC TGGGCGCGCT
GGGCAGAGGC AGCACCTGCT TTTTCCCTAC CCTTCCTCGA TTCTGTCCGT GAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.