||ORF Nucleotide Sequence (Length: 738bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||14-3-3 protein theta
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from HY044745.1, BC093019.1,
BC050601.1 and AA729400.1.
On Jun 21, 2013 this sequence version replaced gi:21464103.
Summary: This gene product belongs to the 14-3-3 family of proteins
which mediate signal transduction by binding to
phosphoserine-containing proteins. This highly conserved protein
family is found in both plants and mammals, and this protein is 99%
identical to the mouse and rat orthologs. This gene is upregulated
in patients with amyotrophic lateral sclerosis. It contains in its
5' UTR a 6 bp tandem repeat sequence which is polymorphic, however,
there is no correlation between the repeat number and the disease.
[provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC056867.1, X57347.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.