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MAL2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAL2
Entrez Gene ID 114569
Full Name mal, T-cell differentiation protein 2 (gene/pseudogene)
General protein information
Preferred Names
protein MAL2
Names
protein MAL2
MAL2 proteolipid protein
MAL proteolipid protein 2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q23

Summary This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

609684


mRNA and Protein(s)

mRNA Protein Name
XM_011516807 XP_011515109 protein MAL2 isoform X1
NM_052886 NP_443118 protein MAL2


Homo sapiens (human) MAL2 NP_443118.1
Pan troglodytes (chimpanzee) MAL2 XP_001142529.1
Macaca mulatta (Rhesus monkey) LOC705045 XP_001093414.1
Canis lupus familiaris (dog) MAL2 XP_851266.1
Bos taurus (cattle) MAL2 NP_001075188.1
Mus musculus (house mouse) Mal2 NP_849251.1
Rattus norvegicus (Norway rat) Mal2 NP_942081.2
Gallus gallus (chicken) MAL2 NP_001012573.2
Danio rerio (zebrafish) zgc:195265 NP_001129449.1
Danio rerio (zebrafish) LOC100332185 XP_002664850.1
Xenopus (Silurana) tropicalis (western clawed frog) mal2 NP_001106628.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MAL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu74744 XM_011516807 PREDICTED: Homo sapiens mal, T-cell differentiation protein 2 (gene/pseudogene) (MAL2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu02098
NM_052886 Homo sapiens mal, T-cell differentiation protein 2 (gene/pseudogene) (MAL2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
Starting from $49.50
$99.00

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu74744
Clone ID Related Accession (Same CDS sequence) XM_011516807
Accession Version XM_011516807.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 360bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product protein MAL2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008046.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
ATGTCGGCCG GCGGAGCGTC AGTCCCGCCG CCCCCGAACC CCGCCGTGTC CTTCCCGCCG 
CCCCGGGTCA CCCTGCCCGC CGGCCCCGAC ATCCTGCGGA CCTACTCGGG CGCCTTCGTC
TGCCTGGAGA TTGATTTTGC CTACCATTTT ACAGTATTTG TCTTCTATTT TGGAGCCTTT
TTATTGGAAG CAGCAGCCAC ATCCCTGCAT GATTTGCATT GCAATACAAC CATAACCGGG
CAGCCACTCC TGAGTGATAA CCAGTATAAC ATAAACGTAG CAGCCTCAAT TTTTGCCTTT
ATGACGACAG CTTGTTATGG TTGCAGTTTG GGTCTGGCTT TACGAAGATG GCGACCGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011515109.1
CDS55..414
Misc Feature(1)184..390(+)
Translation

Target ORF information:

RefSeq Version XM_011516807
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens mal, T-cell differentiation protein 2 (gene/pseudogene) (MAL2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011516807

ORF Insert Sequence:

1
61
121
181
241
301
ATGTCGGCCG GCGGAGCGTC AGTCCCGCCG CCCCCGAACC CCGCCGTGTC CTTCCCGCCG 
CCCCGGGTCA CCCTGCCCGC CGGCCCCGAC ATCCTGCGGA CCTACTCGGG CGCCTTCGTC
TGCCTGGAGA TTGATTTTGC CTACCATTTT ACAGTATTTG TCTTCTATTT TGGAGCCTTT
TTATTGGAAG CAGCAGCCAC ATCCCTGCAT GATTTGCATT GCAATACAAC CATAACCGGG
CAGCCACTCC TGAGTGATAA CCAGTATAAC ATAAACGTAG CAGCCTCAAT TTTTGCCTTT
ATGACGACAG CTTGTTATGG TTGCAGTTTG GGTCTGGCTT TACGAAGATG GCGACCGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02098
Clone ID Related Accession (Same CDS sequence) NM_052886
Accession Version NM_052886.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 531bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product protein MAL2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CV574204.1 and AY007723.1. On Jun 23, 2006 this sequence version replaced gi:16418396. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY007723.1, BX441729.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
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361
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481
ATGTCGGCCG GCGGAGCGTC AGTCCCGCCG CCCCCGAACC CCGCCGTGTC CTTCCCGCCG 
CCCCGGGTCA CCCTGCCCGC CGGCCCCGAC ATCCTGCGGA CCTACTCGGG CGCCTTCGTC
TGCCTGGAGA TTCTGTTCGG GGGTCTTGTC TGGATTTTGG TTGCCTCCTC CAATGTTCCT
CTACCTCTAC TACAAGGATG GGTCATGTTT GTGTCCGTGA CAGCGTTTTT CTTTTCGCTC
CTCTTTCTGG GCATGTTCCT CTCTGGCATG GTGGCTCAAA TTGATGCTAA CTGGAACTTC
CTGGATTTTG CCTACCATTT TACAGTATTT GTCTTCTATT TTGGAGCCTT TTTATTGGAA
GCAGCAGCCA CATCCCTGCA TGATTTGCAT TGCAATACAA CCATAACCGG GCAGCCACTC
CTGAGTGATA ACCAGTATAA CATAAACGTA GCAGCCTCAA TTTTTGCCTT TATGACGACA
GCTTGTTATG GTTGCAGTTT GGGTCTGGCT TTACGAAGAT GGCGACCGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_443118.1
CDS103..633
Misc Feature(1)13..15(+)
Misc Feature(2)196..609(+)
Misc Feature(3)205..267(+)
Misc Feature(4)301..363(+)
Misc Feature(5)409..471(+)
Misc Feature(6)550..612(+)
Exon (1)1..234
Gene:MAL2
Gene Synonym:
Exon (2)235..405
Gene:MAL2
Gene Synonym:
Exon (3)406..561
Gene:MAL2
Gene Synonym:
Exon (4)562..2818
Gene:MAL2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_052886
Organism Homo sapiens (human)
Definition Homo sapiens mal, T-cell differentiation protein 2 (gene/pseudogene) (MAL2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_052886

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGTCGGCCG GCGGAGCGTC AGTCCCGCCG CCCCCGAACC CCGCCGTGTC CTTCCCGCCG 
CCCCGGGTCA CCCTGCCCGC CGGCCCCGAC ATCCTGCGGA CCTACTCGGG CGCCTTCGTC
TGCCTGGAGA TTCTGTTCGG GGGTCTTGTC TGGATTTTGG TTGCCTCCTC CAATGTTCCT
CTACCTCTAC TACAAGGATG GGTCATGTTT GTGTCCGTGA CAGCGTTTTT CTTTTCGCTC
CTCTTTCTGG GCATGTTCCT CTCTGGCATG GTGGCTCAAA TTGATGCTAA CTGGAACTTC
CTGGATTTTG CCTACCATTT TACAGTATTT GTCTTCTATT TTGGAGCCTT TTTATTGGAA
GCAGCAGCCA CATCCCTGCA TGATTTGCAT TGCAATACAA CCATAACCGG GCAGCCACTC
CTGAGTGATA ACCAGTATAA CATAAACGTA GCAGCCTCAA TTTTTGCCTT TATGACGACA
GCTTGTTATG GTTGCAGTTT GGGTCTGGCT TTACGAAGAT GGCGACCGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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