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APOA5 apolipoprotein A-V [Homo sapiens (human)]

Gene Symbol APOA5
Entrez Gene ID 116519
Full Name apolipoprotein A-V
Synonyms APOAV, RAP3
General protein information
Preferred Names
apolipoprotein A-V
Names
apolipoprotein A-V
apo-AV
apolipoprotein A5
regeneration-associated protein 3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q23

Summary The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]. lac of sum
Disorder MIM:

606368

Disorder Html: {Hypertriglyceridemia, susceptibility to}, 145750 (3);





The following APOA5 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APOA5 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu15824 NM_052968 Homo sapiens apolipoprotein A-V (APOA5), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379
OHu15824 NM_001166598 Homo sapiens apolipoprotein A-V (APOA5), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu15824
Accession Version NM_052968.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1101bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 04-AUG-2015
Organism Homo sapiens (human)
Product apolipoprotein A-V precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA641693.1, DB184692.1, BC101787.1, AF202889.1 and AP006216.1. This sequence is a reference standard in the RefSeqGene project. On Oct 30, 2009 this sequence version replaced gi:63079708. Summary: The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CB123028.1, DB184692.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGCAAGCA TGGCTGCCGT GCTCACCTGG GCTCTGGCTC TTCTTTCAGC GTTTTCGGCC 
ACCCAGGCAC GGAAAGGCTT CTGGGACTAC TTCAGCCAGA CCAGCGGGGA CAAAGGCAGG
GTGGAGCAGA TCCATCAGCA GAAGATGGCT CGCGAGCCCG CGACCCTGAA AGACAGCCTT
GAGCAAGACC TCAACAATAT GAACAAGTTC CTGGAAAAGC TGAGGCCTCT GAGTGGGAGC
GAGGCTCCTC GGCTCCCACA GGACCCGGTG GGCATGCGGC GGCAGCTGCA GGAGGAGTTG
GAGGAGGTGA AGGCTCGCCT CCAGCCCTAC ATGGCAGAGG CGCACGAGCT GGTGGGCTGG
AATTTGGAGG GCTTGCGGCA GCAACTGAAG CCCTACACGA TGGATCTGAT GGAGCAGGTG
GCCCTGCGCG TGCAGGAGCT GCAGGAGCAG TTGCGCGTGG TGGGGGAAGA CACCAAGGCC
CAGTTGCTGG GGGGCGTGGA CGAGGCTTGG GCTTTGCTGC AGGGACTGCA GAGCCGCGTG
GTGCACCACA CCGGCCGCTT CAAAGAGCTC TTCCACCCAT ACGCCGAGAG CCTGGTGAGC
GGCATCGGGC GCCACGTGCA GGAGCTGCAC CGCAGTGTGG CTCCGCACGC CCCCGCCAGC
CCCGCGCGCC TCAGTCGCTG CGTGCAGGTG CTCTCCCGGA AGCTCACGCT CAAGGCCAAG
GCCCTGCACG CACGCATCCA GCAGAACCTG GACCAGCTGC GCGAAGAGCT CAGCAGAGCC
TTTGCAGGCA CTGGGACTGA GGAAGGGGCC GGCCCGGACC CCCAGATGCT CTCCGAGGAG
GTGCGCCAGC GACTTCAGGC TTTCCGCCAG GACACCTACC TGCAGATAGC TGCCTTCACT
CGCGCCATCG ACCAGGAGAC TGAGGAGGTC CAGCAGCAGC TGGCGCCACC TCCACCAGGC
CACAGTGCCT TCGCCCCAGA GTTTCAACAA ACAGACAGTG GCAAGGTTCT GAGCAAGCTG
CAGGCCCGTC TGGATGACCT GTGGGAAGAC ATCACTCACA GCCTTCATGA CCAGGGCCAC
AGCCATCTGG GGGACCCCTG A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_443200.2
CDS74..1174
Misc Feature(1)35..37(+)
Misc Feature(2)248..250(+)
Misc Feature(3)305..844(+)
Exon (1)1..41
Gene:APOA5
Gene Synonym:
Exon (2)42..122
Gene:APOA5
Gene Synonym:
Exon (3)123..234
Gene:APOA5
Gene Synonym:
Exon (4)235..1932
Gene:APOA5
Gene Synonym:
Translation
Position Chain Variation Link
4 4 a, g dbSNP:767950624
9 9 a, g dbSNP:45611741
22 22 c, t dbSNP:186726407
32 32 a, g dbSNP:574840114
42 42 a, g dbSNP:749614750
43 43 a, c dbSNP:777409975
44 44 c, t dbSNP:777866427
52 52 a, g dbSNP:769382208
63 63 c, g dbSNP:201424117
68 68 c, g dbSNP:780750063
69 69 a, c dbSNP:754912668
71 71 a, g dbSNP:651821
81 81 -, gca dbSNP:749006602
90 90 c, t dbSNP:779809358
91 91 c, t dbSNP:199724136
116 116 -, ctt dbSNP:755668851
129 129 c, g, t dbSNP:3135506
130 130 c, g, t dbSNP:537146220
137 137 c, t dbSNP:751538202
143 143 a, c dbSNP:144178633
150 150 c, g dbSNP:548745995
158 158 a, g dbSNP:139630081
176 176 a, g dbSNP:765565265
177 177 a, g dbSNP:184390502
178 178 c, t dbSNP:566002026
179 179 c, g dbSNP:146323308
184 184 a, c, t dbSNP:34282181
192 192 g, t dbSNP:148778842
205 205 a, c dbSNP:12287066
214 214 g, t dbSNP:778942385
217 217 a, g dbSNP:770878204
222 222 c, t dbSNP:748972080
226 226 a, c, t dbSNP:149652056
227 227 a, g dbSNP:755144803
238 238 c, g dbSNP:138300114
241 241 a, c, g dbSNP:147142271
252 252 a, t dbSNP:773988647
268 268 c, t dbSNP:770971777
272 272 a, g dbSNP:372084940
297 297 a, g dbSNP:773108378
313 313 a, c, t dbSNP:565510415
314 314 a, g dbSNP:775696556
338 338 a, c dbSNP:772266582
339 339 c, t dbSNP:746011485
345 345 a, g dbSNP:778824656
351 351 a, g dbSNP:757827003
353 353 c, t dbSNP:201686049
354 354 g, t dbSNP:778302124
356 356 c, t dbSNP:756437615
362 362 a, c, t dbSNP:201079485
367 367 a, c, g dbSNP:143382500
368 368 a, g dbSNP:138033117
369 369 a, g dbSNP:201115317
377 377 a, g dbSNP:762480809
386 386 g, t dbSNP:146964666
394 394 c, t dbSNP:765158935
398 398 c, t dbSNP:534852399
404 404 a, g dbSNP:371403919
406 406 g, t dbSNP:565944950
415 415 a, g dbSNP:746064552
425 425 a, g dbSNP:774584367
433 433 c, g dbSNP:770946707
449 449 a, c dbSNP:140178861
458 458 a, c dbSNP:199974844
485 485 c, g dbSNP:756677678
488 488 c, t dbSNP:121917821
493 493 a, g dbSNP:748592317
500 500 a, c dbSNP:781667094
500 500 -, c dbSNP:777046568
502 502 c, t dbSNP:754727126
503 503 a, g dbSNP:751198486
507 507 a, g dbSNP:368739905
511 511 g, t dbSNP:538946034
528 528 a, g dbSNP:570296174
530 530 a, g dbSNP:3135507
539 539 g, t dbSNP:761704440
553 553 c, t dbSNP:530069257
563 563 a, c, g dbSNP:760422549
566 566 c, g dbSNP:774440773
567 567 -, g dbSNP:764366547
568 568 a, c dbSNP:771125152
573 573 a, t dbSNP:762999453
577 577 a, c, g dbSNP:370837638
584 584 a, g dbSNP:748643764
591 591 c, t dbSNP:781745888
592 592 a, g dbSNP:149112933
594 594 a, g dbSNP:747334731
597 597 c, g dbSNP:779590119
602 602 a, c dbSNP:758058040
606 606 c, g dbSNP:749939049
607 607 c, t dbSNP:778370338
608 608 c, t dbSNP:756703832
611 611 c, g dbSNP:753800578
612 612 a, g dbSNP:34543602
619 619 c, t dbSNP:763952491
621 621 a, t dbSNP:760475712
624 624 c, g dbSNP:201229911
626 626 a, g, t dbSNP:2075291
627 627 a, g dbSNP:144211639
630 630 a, g dbSNP:773214283
642 642 c, t dbSNP:770016674
651 651 c, t dbSNP:761948955
652 652 a, g dbSNP:528247453
653 653 c, t dbSNP:769230421
670 670 a, g dbSNP:374702553
672 672 a, g dbSNP:780433260
674 674 g, t dbSNP:771668280
679 679 c, t dbSNP:140482460
680 680 g, t dbSNP:778493133
683 683 c, t dbSNP:546060544
686 686 c, t dbSNP:753285841
688 688 a, c, g, t dbSNP:752477156
691 691 g, t dbSNP:767323687
695 695 a, g dbSNP:759203957
698 698 c, t dbSNP:750706052
705 705 g, t dbSNP:747958115
709 709 c, t dbSNP:371545524
710 710 a, g dbSNP:376891081
717 717 c, t dbSNP:76753536
721 721 c, t dbSNP:370906477
722 722 -, c dbSNP:71469115
723 723 a, c dbSNP:775809738
737 737 a, g dbSNP:772514533
738 738 c, t dbSNP:746148058
741 741 a, g dbSNP:774006043
749 749 c, t dbSNP:770555817
752 752 c, t dbSNP:748861443
755 755 a, g dbSNP:777235686
766 766 c, g dbSNP:756056633
769 769 a, c, g dbSNP:146781249
771 771 a, g dbSNP:563462071
780 780 a, c dbSNP:751344537
781 781 c, g dbSNP:374068229
783 783 c, t dbSNP:765615181
785 785 a, c dbSNP:757551915
799 799 a, g dbSNP:754017703
800 800 a, c dbSNP:764254615
802 802 c, t dbSNP:760626837
803 803 a, g dbSNP:776065144
806 806 c, t dbSNP:376196775
811 811 c, g dbSNP:759950783
813 813 a, g dbSNP:774692220
815 815 c, g dbSNP:770609003
820 820 a, c dbSNP:748918554
821 821 a, c dbSNP:772805108
823 823 a, g dbSNP:769378326
824 824 a, g dbSNP:372966851
831 831 c, t dbSNP:781206581
833 833 c, t dbSNP:754861714
836 836 a, g dbSNP:746869568
837 837 a, g dbSNP:543375884
848 848 a, t dbSNP:758216033
850 850 a, t dbSNP:754142312
857 857 g, t dbSNP:764151068
860 860 a, g dbSNP:756228312
864 864 a, c dbSNP:752705893
875 875 a, g dbSNP:574363219
877 877 a, g dbSNP:760003813
881 881 a, g dbSNP:751970941
884 884 a, g dbSNP:766754499
888 888 a, c, t dbSNP:772922485
893 893 c, g dbSNP:769276750
896 896 -, c dbSNP:775644896
896 896 c, t dbSNP:149808404
897 897 -, a dbSNP:34767938
901 901 -, g dbSNP:771919465
903 903 c, t dbSNP:375950328
907 907 c, g dbSNP:768681709
910 910 a, g, t dbSNP:150667142
911 911 g, t dbSNP:771994073
914 914 a, g dbSNP:142901239
917 917 a, c dbSNP:778114184
918 918 a, g dbSNP:756286096
921 921 a, g dbSNP:140206085
923 923 c, t dbSNP:781109287
938 938 c, t dbSNP:755003082
939 939 a, g dbSNP:752093878
947 947 a, g dbSNP:766805532
948 948 c, t dbSNP:34832733
952 952 c, t dbSNP:750744192
955 955 a, g dbSNP:113986025
956 956 c, t dbSNP:765011895
959 959 a, g dbSNP:199689773
960 960 g, t dbSNP:761343549
962 962 -, ag dbSNP:745876713
964 964 a, t dbSNP:776257058
966 966 c, t dbSNP:571858965
967 967 c, t dbSNP:372918863
975 975 a, g dbSNP:370089477
978 978 c, t dbSNP:775577612
992 992 a, g dbSNP:772118863
1010 1010 c, t dbSNP:147528707
1013 1013 c, t dbSNP:778540867
1017 1017 c, t dbSNP:143292359
1018 1018 a, g dbSNP:200738033
1029 1029 c, t dbSNP:781438417
1035 1035 a, t dbSNP:201201147
1046 1046 a, g dbSNP:751582219
1048 1048 c, t dbSNP:137942813
1054 1054 a, g dbSNP:758906155
1063 1063 -, aaca dbSNP:774150500
1071 1071 a, g dbSNP:750842108
1073 1073 a, g dbSNP:61743807
1074 1074 -, g dbSNP:760743872
1074 1074 g, t dbSNP:147349873
1075 1075 a, c dbSNP:757598085
1096 1096 c, g dbSNP:7120555
1099 1099 a, c dbSNP:753434004
1100 1100 c, t dbSNP:763777417
1109 1109 a, g dbSNP:369952307
1111 1111 c, t dbSNP:775135279
1125 1125 c, t dbSNP:767603144
1128 1128 c, t dbSNP:759367504
1136 1136 c, t dbSNP:556600766
1148 1148 a, g dbSNP:774294731
1161 1161 a, g, t dbSNP:749327504
1168 1168 c, t dbSNP:749047023
1180 1180 g, t dbSNP:776853216
1182 1182 a, c dbSNP:768852938
1183 1183 a, c dbSNP:375881609
1186 1186 c, t dbSNP:185060854
1199 1199 c, t dbSNP:369734876
1205 1205 c, t dbSNP:619054
1211 1211 c, t dbSNP:779407057
1214 1214 a, c, g dbSNP:547858278
1216 1216 a, g dbSNP:763902687
1218 1218 a, g, t dbSNP:752304853
1221 1221 g, t dbSNP:369740771
1223 1223 a, g dbSNP:534277514
1224 1224 g, t dbSNP:376976905
1225 1225 c, t dbSNP:766281541
1233 1233 a, c dbSNP:192708363
1240 1240 a, g dbSNP:780165902
1250 1250 c, t dbSNP:34089864
1281 1281 a, t dbSNP:781588485
1297 1297 c, g dbSNP:112650726
1319 1319 a, g dbSNP:45459507
1332 1332 c, t dbSNP:2266788
1334 1334 c, t dbSNP:563561446
1346 1346 c, t dbSNP:114627122
1365 1365 c, t dbSNP:188133936
1382 1382 a, t dbSNP:560721606
1402 1402 a, g dbSNP:556197262
1458 1458 -, ga dbSNP:397897431
1459 1459 -, ga dbSNP:72525532
1462 1462 -, ga dbSNP:45596738
1463 1463 -, ag dbSNP:148759216
1465 1465 c, t dbSNP:540668109
1479 1479 a, g dbSNP:76463524
1518 1518 c, t dbSNP:558507418
1568 1568 c, t dbSNP:33984246
1593 1593 a, g dbSNP:576576803
1595 1595 a, g dbSNP:556776664
1657 1657 -, gag dbSNP:759635244
1671 1671 c, g dbSNP:754460898
1682 1682 a, g dbSNP:566731687
1699 1699 c, g dbSNP:536542142
1717 1717 a, g dbSNP:764436886
1720 1720 c, t dbSNP:765775223
1732 1732 a, g dbSNP:182378073
1749 1749 a, g dbSNP:779275499
1769 1769 a, t dbSNP:554191422
1775 1775 c, t dbSNP:534211586
1811 1811 g, t dbSNP:554471735
1816 1816 a, t dbSNP:35009896
1834 1834 a, g dbSNP:760425054
1865 1865 a, g dbSNP:35822632
1887 1887 c, g dbSNP:146109377
1908 1908 a, t dbSNP:772948091
1909 1909 c, g dbSNP:551919092

Target ORF information:

RefSeq Version NM_052968
Organism Homo sapiens (human)
Definition Homo sapiens apolipoprotein A-V (APOA5), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_052968

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGCAAGCA TGGCTGCCGT GCTCACCTGG GCTCTGGCTC TTCTTTCAGC GTTTTCGGCC 
ACCCAGGCAC GGAAAGGCTT CTGGGACTAC TTCAGCCAGA CCAGCGGGGA CAAAGGCAGG
GTGGAGCAGA TCCATCAGCA GAAGATGGCT CGCGAGCCCG CGACCCTGAA AGACAGCCTT
GAGCAAGACC TCAACAATAT GAACAAGTTC CTGGAAAAGC TGAGGCCTCT GAGTGGGAGC
GAGGCTCCTC GGCTCCCACA GGACCCGGTG GGCATGCGGC GGCAGCTGCA GGAGGAGTTG
GAGGAGGTGA AGGCTCGCCT CCAGCCCTAC ATGGCAGAGG CGCACGAGCT GGTGGGCTGG
AATTTGGAGG GCTTGCGGCA GCAACTGAAG CCCTACACGA TGGATCTGAT GGAGCAGGTG
GCCCTGCGCG TGCAGGAGCT GCAGGAGCAG TTGCGCGTGG TGGGGGAAGA CACCAAGGCC
CAGTTGCTGG GGGGCGTGGA CGAGGCTTGG GCTTTGCTGC AGGGACTGCA GAGCCGCGTG
GTGCACCACA CCGGCCGCTT CAAAGAGCTC TTCCACCCAT ACGCCGAGAG CCTGGTGAGC
GGCATCGGGC GCCACGTGCA GGAGCTGCAC CGCAGTGTGG CTCCGCACGC CCCCGCCAGC
CCCGCGCGCC TCAGTCGCTG CGTGCAGGTG CTCTCCCGGA AGCTCACGCT CAAGGCCAAG
GCCCTGCACG CACGCATCCA GCAGAACCTG GACCAGCTGC GCGAAGAGCT CAGCAGAGCC
TTTGCAGGCA CTGGGACTGA GGAAGGGGCC GGCCCGGACC CCCAGATGCT CTCCGAGGAG
GTGCGCCAGC GACTTCAGGC TTTCCGCCAG GACACCTACC TGCAGATAGC TGCCTTCACT
CGCGCCATCG ACCAGGAGAC TGAGGAGGTC CAGCAGCAGC TGGCGCCACC TCCACCAGGC
CACAGTGCCT TCGCCCCAGA GTTTCAACAA ACAGACAGTG GCAAGGTTCT GAGCAAGCTG
CAGGCCCGTC TGGATGACCT GTGGGAAGAC ATCACTCACA GCCTTCATGA CCAGGGCCAC
AGCCATCTGG GGGACCCCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu15824
Accession Version NM_001166598.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1101bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 04-AUG-2015
Organism Homo sapiens (human)
Product apolipoprotein A-V precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA641693.1, AF202889.1 and AP006216.1. Summary: The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA641318.1, AK292739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGCAAGCA TGGCTGCCGT GCTCACCTGG GCTCTGGCTC TTCTTTCAGC GTTTTCGGCC 
ACCCAGGCAC GGAAAGGCTT CTGGGACTAC TTCAGCCAGA CCAGCGGGGA CAAAGGCAGG
GTGGAGCAGA TCCATCAGCA GAAGATGGCT CGCGAGCCCG CGACCCTGAA AGACAGCCTT
GAGCAAGACC TCAACAATAT GAACAAGTTC CTGGAAAAGC TGAGGCCTCT GAGTGGGAGC
GAGGCTCCTC GGCTCCCACA GGACCCGGTG GGCATGCGGC GGCAGCTGCA GGAGGAGTTG
GAGGAGGTGA AGGCTCGCCT CCAGCCCTAC ATGGCAGAGG CGCACGAGCT GGTGGGCTGG
AATTTGGAGG GCTTGCGGCA GCAACTGAAG CCCTACACGA TGGATCTGAT GGAGCAGGTG
GCCCTGCGCG TGCAGGAGCT GCAGGAGCAG TTGCGCGTGG TGGGGGAAGA CACCAAGGCC
CAGTTGCTGG GGGGCGTGGA CGAGGCTTGG GCTTTGCTGC AGGGACTGCA GAGCCGCGTG
GTGCACCACA CCGGCCGCTT CAAAGAGCTC TTCCACCCAT ACGCCGAGAG CCTGGTGAGC
GGCATCGGGC GCCACGTGCA GGAGCTGCAC CGCAGTGTGG CTCCGCACGC CCCCGCCAGC
CCCGCGCGCC TCAGTCGCTG CGTGCAGGTG CTCTCCCGGA AGCTCACGCT CAAGGCCAAG
GCCCTGCACG CACGCATCCA GCAGAACCTG GACCAGCTGC GCGAAGAGCT CAGCAGAGCC
TTTGCAGGCA CTGGGACTGA GGAAGGGGCC GGCCCGGACC CCCAGATGCT CTCCGAGGAG
GTGCGCCAGC GACTTCAGGC TTTCCGCCAG GACACCTACC TGCAGATAGC TGCCTTCACT
CGCGCCATCG ACCAGGAGAC TGAGGAGGTC CAGCAGCAGC TGGCGCCACC TCCACCAGGC
CACAGTGCCT TCGCCCCAGA GTTTCAACAA ACAGACAGTG GCAAGGTTCT GAGCAAGCTG
CAGGCCCGTC TGGATGACCT GTGGGAAGAC ATCACTCACA GCCTTCATGA CCAGGGCCAC
AGCCATCTGG GGGACCCCTG A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001160070.1
CDS50..1150
Misc Feature(1)35..37(+)
Misc Feature(2)224..226(+)
Misc Feature(3)281..820(+)
Exon (1)1..41
Gene:APOA5
Gene Synonym:
Exon (2)42..98
Gene:APOA5
Gene Synonym:
Exon (3)99..210
Gene:APOA5
Gene Synonym:
Exon (4)211..1908
Gene:APOA5
Gene Synonym:
Translation
Position Chain Variation Link
4 4 a, g dbSNP:767950624
9 9 a, g dbSNP:45611741
22 22 c, t dbSNP:186726407
32 32 a, g dbSNP:574840114
44 44 c, g dbSNP:780750063
45 45 a, c dbSNP:754912668
47 47 a, g dbSNP:651821
57 57 -, gca dbSNP:749006602
66 66 c, t dbSNP:779809358
67 67 c, t dbSNP:199724136
92 92 -, ctt dbSNP:755668851
105 105 c, g, t dbSNP:3135506
106 106 c, g, t dbSNP:537146220
113 113 c, t dbSNP:751538202
119 119 a, c dbSNP:144178633
126 126 c, g dbSNP:548745995
134 134 a, g dbSNP:139630081
152 152 a, g dbSNP:765565265
153 153 a, g dbSNP:184390502
154 154 c, t dbSNP:566002026
155 155 c, g dbSNP:146323308
160 160 a, c, t dbSNP:34282181
168 168 g, t dbSNP:148778842
181 181 a, c dbSNP:12287066
190 190 g, t dbSNP:778942385
193 193 a, g dbSNP:770878204
198 198 c, t dbSNP:748972080
202 202 a, c, t dbSNP:149652056
203 203 a, g dbSNP:755144803
214 214 c, g dbSNP:138300114
217 217 a, c, g dbSNP:147142271
228 228 a, t dbSNP:773988647
244 244 c, t dbSNP:770971777
248 248 a, g dbSNP:372084940
273 273 a, g dbSNP:773108378
289 289 a, c, t dbSNP:565510415
290 290 a, g dbSNP:775696556
314 314 a, c dbSNP:772266582
315 315 c, t dbSNP:746011485
321 321 a, g dbSNP:778824656
327 327 a, g dbSNP:757827003
329 329 c, t dbSNP:201686049
330 330 g, t dbSNP:778302124
332 332 c, t dbSNP:756437615
338 338 a, c, t dbSNP:201079485
343 343 a, c, g dbSNP:143382500
344 344 a, g dbSNP:138033117
345 345 a, g dbSNP:201115317
353 353 a, g dbSNP:762480809
362 362 g, t dbSNP:146964666
370 370 c, t dbSNP:765158935
374 374 c, t dbSNP:534852399
380 380 a, g dbSNP:371403919
382 382 g, t dbSNP:565944950
391 391 a, g dbSNP:746064552
401 401 a, g dbSNP:774584367
409 409 c, g dbSNP:770946707
425 425 a, c dbSNP:140178861
434 434 a, c dbSNP:199974844
461 461 c, g dbSNP:756677678
464 464 c, t dbSNP:121917821
469 469 a, g dbSNP:748592317
476 476 a, c dbSNP:781667094
476 476 -, c dbSNP:777046568
478 478 c, t dbSNP:754727126
479 479 a, g dbSNP:751198486
483 483 a, g dbSNP:368739905
487 487 g, t dbSNP:538946034
504 504 a, g dbSNP:570296174
506 506 a, g dbSNP:3135507
515 515 g, t dbSNP:761704440
529 529 c, t dbSNP:530069257
539 539 a, c, g dbSNP:760422549
542 542 c, g dbSNP:774440773
543 543 -, g dbSNP:764366547
544 544 a, c dbSNP:771125152
549 549 a, t dbSNP:762999453
553 553 a, c, g dbSNP:370837638
560 560 a, g dbSNP:748643764
567 567 c, t dbSNP:781745888
568 568 a, g dbSNP:149112933
570 570 a, g dbSNP:747334731
573 573 c, g dbSNP:779590119
578 578 a, c dbSNP:758058040
582 582 c, g dbSNP:749939049
583 583 c, t dbSNP:778370338
584 584 c, t dbSNP:756703832
587 587 c, g dbSNP:753800578
588 588 a, g dbSNP:34543602
595 595 c, t dbSNP:763952491
597 597 a, t dbSNP:760475712
600 600 c, g dbSNP:201229911
602 602 a, g, t dbSNP:2075291
603 603 a, g dbSNP:144211639
606 606 a, g dbSNP:773214283
618 618 c, t dbSNP:770016674
627 627 c, t dbSNP:761948955
628 628 a, g dbSNP:528247453
629 629 c, t dbSNP:769230421
646 646 a, g dbSNP:374702553
648 648 a, g dbSNP:780433260
650 650 g, t dbSNP:771668280
655 655 c, t dbSNP:140482460
656 656 g, t dbSNP:778493133
659 659 c, t dbSNP:546060544
662 662 c, t dbSNP:753285841
664 664 a, c, g, t dbSNP:752477156
667 667 g, t dbSNP:767323687
671 671 a, g dbSNP:759203957
674 674 c, t dbSNP:750706052
681 681 g, t dbSNP:747958115
685 685 c, t dbSNP:371545524
686 686 a, g dbSNP:376891081
693 693 c, t dbSNP:76753536
697 697 c, t dbSNP:370906477
698 698 -, c dbSNP:71469115
699 699 a, c dbSNP:775809738
713 713 a, g dbSNP:772514533
714 714 c, t dbSNP:746148058
717 717 a, g dbSNP:774006043
725 725 c, t dbSNP:770555817
728 728 c, t dbSNP:748861443
731 731 a, g dbSNP:777235686
742 742 c, g dbSNP:756056633
745 745 a, c, g dbSNP:146781249
747 747 a, g dbSNP:563462071
756 756 a, c dbSNP:751344537
757 757 c, g dbSNP:374068229
759 759 c, t dbSNP:765615181
761 761 a, c dbSNP:757551915
775 775 a, g dbSNP:754017703
776 776 a, c dbSNP:764254615
778 778 c, t dbSNP:760626837
779 779 a, g dbSNP:776065144
782 782 c, t dbSNP:376196775
787 787 c, g dbSNP:759950783
789 789 a, g dbSNP:774692220
791 791 c, g dbSNP:770609003
796 796 a, c dbSNP:748918554
797 797 a, c dbSNP:772805108
799 799 a, g dbSNP:769378326
800 800 a, g dbSNP:372966851
807 807 c, t dbSNP:781206581
809 809 c, t dbSNP:754861714
812 812 a, g dbSNP:746869568
813 813 a, g dbSNP:543375884
824 824 a, t dbSNP:758216033
826 826 a, t dbSNP:754142312
833 833 g, t dbSNP:764151068
836 836 a, g dbSNP:756228312
840 840 a, c dbSNP:752705893
851 851 a, g dbSNP:574363219
853 853 a, g dbSNP:760003813
857 857 a, g dbSNP:751970941
860 860 a, g dbSNP:766754499
864 864 a, c, t dbSNP:772922485
869 869 c, g dbSNP:769276750
872 872 -, c dbSNP:775644896
872 872 c, t dbSNP:149808404
873 873 -, a dbSNP:34767938
877 877 -, g dbSNP:771919465
879 879 c, t dbSNP:375950328
883 883 c, g dbSNP:768681709
886 886 a, g, t dbSNP:150667142
887 887 g, t dbSNP:771994073
890 890 a, g dbSNP:142901239
893 893 a, c dbSNP:778114184
894 894 a, g dbSNP:756286096
897 897 a, g dbSNP:140206085
899 899 c, t dbSNP:781109287
914 914 c, t dbSNP:755003082
915 915 a, g dbSNP:752093878
923 923 a, g dbSNP:766805532
924 924 c, t dbSNP:34832733
928 928 c, t dbSNP:750744192
931 931 a, g dbSNP:113986025
932 932 c, t dbSNP:765011895
935 935 a, g dbSNP:199689773
936 936 g, t dbSNP:761343549
938 938 -, ag dbSNP:745876713
940 940 a, t dbSNP:776257058
942 942 c, t dbSNP:571858965
943 943 c, t dbSNP:372918863
951 951 a, g dbSNP:370089477
954 954 c, t dbSNP:775577612
968 968 a, g dbSNP:772118863
986 986 c, t dbSNP:147528707
989 989 c, t dbSNP:778540867
993 993 c, t dbSNP:143292359
994 994 a, g dbSNP:200738033
1005 1005 c, t dbSNP:781438417
1011 1011 a, t dbSNP:201201147
1022 1022 a, g dbSNP:751582219
1024 1024 c, t dbSNP:137942813
1030 1030 a, g dbSNP:758906155
1039 1039 -, aaca dbSNP:774150500
1047 1047 a, g dbSNP:750842108
1049 1049 a, g dbSNP:61743807
1050 1050 -, g dbSNP:760743872
1050 1050 g, t dbSNP:147349873
1051 1051 a, c dbSNP:757598085
1072 1072 c, g dbSNP:7120555
1075 1075 a, c dbSNP:753434004
1076 1076 c, t dbSNP:763777417
1085 1085 a, g dbSNP:369952307
1087 1087 c, t dbSNP:775135279
1101 1101 c, t dbSNP:767603144
1104 1104 c, t dbSNP:759367504
1112 1112 c, t dbSNP:556600766
1124 1124 a, g dbSNP:774294731
1137 1137 a, g, t dbSNP:749327504
1144 1144 c, t dbSNP:749047023
1156 1156 g, t dbSNP:776853216
1158 1158 a, c dbSNP:768852938
1159 1159 a, c dbSNP:375881609
1162 1162 c, t dbSNP:185060854
1175 1175 c, t dbSNP:369734876
1181 1181 c, t dbSNP:619054
1187 1187 c, t dbSNP:779407057
1190 1190 a, c, g dbSNP:547858278
1192 1192 a, g dbSNP:763902687
1194 1194 a, g, t dbSNP:752304853
1197 1197 g, t dbSNP:369740771
1199 1199 a, g dbSNP:534277514
1200 1200 g, t dbSNP:376976905
1201 1201 c, t dbSNP:766281541
1209 1209 a, c dbSNP:192708363
1216 1216 a, g dbSNP:780165902
1226 1226 c, t dbSNP:34089864
1257 1257 a, t dbSNP:781588485
1273 1273 c, g dbSNP:112650726
1295 1295 a, g dbSNP:45459507
1308 1308 c, t dbSNP:2266788
1310 1310 c, t dbSNP:563561446
1322 1322 c, t dbSNP:114627122
1341 1341 c, t dbSNP:188133936
1358 1358 a, t dbSNP:560721606
1378 1378 a, g dbSNP:556197262
1434 1434 -, ga dbSNP:397897431
1435 1435 -, ga dbSNP:72525532
1438 1438 -, ga dbSNP:45596738
1439 1439 -, ag dbSNP:148759216
1441 1441 c, t dbSNP:540668109
1455 1455 a, g dbSNP:76463524
1494 1494 c, t dbSNP:558507418
1544 1544 c, t dbSNP:33984246
1569 1569 a, g dbSNP:576576803
1571 1571 a, g dbSNP:556776664
1633 1633 -, gag dbSNP:759635244
1647 1647 c, g dbSNP:754460898
1658 1658 a, g dbSNP:566731687
1675 1675 c, g dbSNP:536542142
1693 1693 a, g dbSNP:764436886
1696 1696 c, t dbSNP:765775223
1708 1708 a, g dbSNP:182378073
1725 1725 a, g dbSNP:779275499
1745 1745 a, t dbSNP:554191422
1751 1751 c, t dbSNP:534211586
1787 1787 g, t dbSNP:554471735
1792 1792 a, t dbSNP:35009896
1810 1810 a, g dbSNP:760425054
1841 1841 a, g dbSNP:35822632
1863 1863 c, g dbSNP:146109377
1884 1884 a, t dbSNP:772948091
1885 1885 c, g dbSNP:551919092

Target ORF information:

RefSeq Version NM_001166598
Organism Homo sapiens (human)
Definition Homo sapiens apolipoprotein A-V (APOA5), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001166598

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGCAAGCA TGGCTGCCGT GCTCACCTGG GCTCTGGCTC TTCTTTCAGC GTTTTCGGCC 
ACCCAGGCAC GGAAAGGCTT CTGGGACTAC TTCAGCCAGA CCAGCGGGGA CAAAGGCAGG
GTGGAGCAGA TCCATCAGCA GAAGATGGCT CGCGAGCCCG CGACCCTGAA AGACAGCCTT
GAGCAAGACC TCAACAATAT GAACAAGTTC CTGGAAAAGC TGAGGCCTCT GAGTGGGAGC
GAGGCTCCTC GGCTCCCACA GGACCCGGTG GGCATGCGGC GGCAGCTGCA GGAGGAGTTG
GAGGAGGTGA AGGCTCGCCT CCAGCCCTAC ATGGCAGAGG CGCACGAGCT GGTGGGCTGG
AATTTGGAGG GCTTGCGGCA GCAACTGAAG CCCTACACGA TGGATCTGAT GGAGCAGGTG
GCCCTGCGCG TGCAGGAGCT GCAGGAGCAG TTGCGCGTGG TGGGGGAAGA CACCAAGGCC
CAGTTGCTGG GGGGCGTGGA CGAGGCTTGG GCTTTGCTGC AGGGACTGCA GAGCCGCGTG
GTGCACCACA CCGGCCGCTT CAAAGAGCTC TTCCACCCAT ACGCCGAGAG CCTGGTGAGC
GGCATCGGGC GCCACGTGCA GGAGCTGCAC CGCAGTGTGG CTCCGCACGC CCCCGCCAGC
CCCGCGCGCC TCAGTCGCTG CGTGCAGGTG CTCTCCCGGA AGCTCACGCT CAAGGCCAAG
GCCCTGCACG CACGCATCCA GCAGAACCTG GACCAGCTGC GCGAAGAGCT CAGCAGAGCC
TTTGCAGGCA CTGGGACTGA GGAAGGGGCC GGCCCGGACC CCCAGATGCT CTCCGAGGAG
GTGCGCCAGC GACTTCAGGC TTTCCGCCAG GACACCTACC TGCAGATAGC TGCCTTCACT
CGCGCCATCG ACCAGGAGAC TGAGGAGGTC CAGCAGCAGC TGGCGCCACC TCCACCAGGC
CACAGTGCCT TCGCCCCAGA GTTTCAACAA ACAGACAGTG GCAAGGTTCT GAGCAAGCTG
CAGGCCCGTC TGGATGACCT GTGGGAAGAC ATCACTCACA GCCTTCATGA CCAGGGCCAC
AGCCATCTGG GGGACCCCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.