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CLCN5 cDNA ORF clone, Homo sapiens (human)

Gene Symbol CLCN5
Entrez Gene ID 1184
Full Name chloride channel, voltage-sensitive 5
Synonyms CLC5, CLCK2, ClC-5, DENTS, NPHL1, NPHL2, XLRH, XRN, hCIC-K2
General protein information
Preferred Names
H(+)/Cl(-) exchange transporter 5
Names
H(+)/Cl(-) exchange transporter 5
chloride transporter ClC-5
voltage-gated chloride ion channel CLCN5
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp11.23-p11.22

Summary This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]. lac of sum
Disorder MIM:

300008

Disorder Html: Dent disease, 300009 (3); Nephrolithiasis, type I, 310468 (3);

mRNA and Protein(s)

mRNA Protein Name
NM_001282163 NP_001269092 H(+)/Cl(-) exchange transporter 5 isoform d
XM_011543888 XP_011542190 H(+)/Cl(-) exchange transporter 5 isoform X1
XM_011543889 XP_011542191 H(+)/Cl(-) exchange transporter 5 isoform X2
NM_001127899 NP_001121371 H(+)/Cl(-) exchange transporter 5 isoform a
NM_001127898 NP_001121370 H(+)/Cl(-) exchange transporter 5 isoform a
NM_000084 NP_000075 H(+)/Cl(-) exchange transporter 5 isoform b
NM_001272102 NP_001259031 H(+)/Cl(-) exchange transporter 5 isoform c



Homo sapiens (human) CLCN5 NP_001121371.1
Pan troglodytes (chimpanzee) CLCN5 XP_003317509.2
Macaca mulatta (Rhesus monkey) CLCN5 XP_001083186.2
Canis lupus familiaris (dog) CLCN5 XP_005641410.1
Bos taurus (cattle) CLCN5 XP_005228237.1
Mus musculus (house mouse) Clcn5 NP_001230691.1
Rattus norvegicus (Norway rat) Clcn5 NP_058802.1
Gallus gallus (chicken) CLCN5 XP_004940778.1
Danio rerio (zebrafish) si:dkey-22f5.8 XP_001920783.2
Danio rerio (zebrafish) LOC557584 XP_685762.2
Xenopus (Silurana) tropicalis (western clawed frog) clcn5 NP_001039210.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CLCN5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CLCN5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu20940 NM_001282163 Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu56926 XM_011543888 PREDICTED: Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00
OHu56927 XM_011543889 PREDICTED: Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu21666 NM_001127899 Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $580.30
$829.00
OHu21666 NM_001127898 Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $580.30
$829.00
OHu21358
NM_000084 Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu16814 NM_001272102 Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu20940
Clone ID Related Accession (Same CDS sequence) NM_001282163
Accession Version NM_001282163.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2301bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 05-MAY-2014
Organism Homo sapiens (human)
Product H(+)/Cl(-) exchange transporter 5 isoform d
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X91906.1, AC231645.2, BC051691.1, AK025562.1 and AA743724.1. On Aug 21, 2013 this sequence version replaced gi:442535526. Transcript Variant: This variant (4, also known as type 4) lacks several 5' exons but has an alternate 5' exon, and it thus differs in the 5' UTR and uses an alternate start codon, compared to variant 1. The resulting isoform (d) has a shorter and distinct N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X91906.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGTTCCTAC CAGAGGACAA GTCGTACAAT GGTGGAGGAA TAGGTTCTTC AAATAGGATC 
ATGGACTTCT TGGAGGAGCC AATCCCTGGT GTAGGGACCT ATGATGATTT CAATACAATT
GATTGGGTGA GAGAGAAGTC TCGAGACCGG GATAGGCACC GAGAGATTAC CAATAAAAGC
AAAGAGTCAA CATGGGCCTT AATTCACAGT GTGAGTGATG CTTTTTCCGG CTGGTTGTTG
ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG TTAGCTGGTT TGATAGACAT CTCTGCTCAT
TGGATGACAG ACTTAAAAGA AGGTATATGC ACAGGGGGAT TCTGGTTTAA CCATGAACAT
TGTTGCTGGA ACTCTGAGCA TGTCACCTTT GAAGAGAGAG ACAAATGTCC AGAGTGGAAT
AGTTGGTCCC AGCTTATCAT CAGCACAGAT GAGGGAGCCT TTGCCTACAT AGTCAATTAT
TTCATGTACG TCCTCTGGGC TCTCCTATTT GCCTTCCTTG CCGTATCTCT TGTCAAGGTG
TTTGCGCCTT ATGCCTGTGG CTCTGGAATC CCTGAGATAA AAACTATCTT GAGTGGTTTC
ATTATTAGGG GCTATTTGGG TAAGTGGACT CTGGTTATCA AAACCATCAC CTTGGTGCTG
GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA GAGGGCCCTC TAGTGCACGT GGCTTGCTGC
TGTGGGAACA TCCTGTGCCA CTGCTTCAAC AAATACAGGA AGAATGAAGC CAAGCGCAGA
GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT GTATCTGTAG CCTTTGGAGC ACCTATAGGT
GGAGTATTAT TCAGCCTTGA AGAGGTCAGC TACTATTTTC CCCTCAAAAC ATTGTGGCGT
TCATTCTTTG CTGCCTTGGT GGCAGCATTC ACTCTACGCT CCATCAATCC ATTTGGGAAC
AGCCGCCTGG TACTATTTTA TGTGGAGTTT CACACCCCAT GGCATCTCTT TGAGCTCGTG
CCATTCATTC TGCTGGGCAT ATTTGGTGGT CTGTGGGGAG CACTGTTTAT CCGCACAAAC
ATTGCCTGGT GTCGGAAGCG AAAGACCACC CAGTTGGGCA AGTATCCTGT TATAGAGGTA
CTCGTCGTGA CAGCCATCAC TGCCATCCTG GCTTTCCCCA ATGAATACAC TCGGATGAGC
ACAAGTGAGC TCATTTCTGA GCTGTTTAAT GACTGTGGCC TTCTGGACTC CTCCAAGCTC
TGTGATTATG AGAACCGTTT CAACACAAGC AAAGGGGGTG AACTGCCTGA CAGACCGGCT
GGCGTGGGAG TCTACAGTGC AATGTGGCAG CTGGCTTTAA CACTCATACT GAAAATTGTC
ATTACTATAT TCACCTTTGG CATGAAGATC CCTTCTGGCC TCTTTATCCC TAGCATGGCT
GTTGGTGCTA TAGCAGGTCG ACTTCTAGGA GTAGGAATGG AACAGCTGGC TTATTACCAC
CAGGAATGGA CCGTCTTCAA TAGCTGGTGT AGTCAGGGAG CTGATTGCAT CACCCCCGGC
CTTTATGCAA TGGTTGGGGC TGCAGCCTGC TTAGGTGGGG TGACTCGGAT GACTGTTTCT
CTTGTTGTCA TAATGTTTGA ACTGACTGGT GGCTTAGAAT ACATCGTGCC TCTGATGGCT
GCAGCCATGA CAAGCAAGTG GGTGGCAGAT GCTCTTGGGC GGGAGGGCAT CTATGATGCC
CACATCCGTC TCAATGGATA CCCCTTTCTT GAAGCCAAAG AAGAGTTTGC TCATAAGACC
CTGGCAATGG ATGTGATGAA ACCCCGGAGA AATGATCCTT TGTTGACTGT CCTTACTCAG
GACAGTATGA CTGTGGAAGA TGTAGAGACC ATAATCAGTG AAACCACTTA CAGTGGCTTC
CCAGTGGTGG TATCCCGGGA GTCCCAAAGA CTTGTGGGCT TTGTCCTCCG AAGAGATCTC
ATTATTTCAA TTGAAAATGC TCGAAAGAAA CAGGATGGGG TTGTTAGCAC TTCCATCATT
TATTTCACGG AGCATTCTCC TCCATTGCCA CCATACACTC CACCCACTCT AAAGCTTCGG
AACATCCTCG ATCTCAGCCC CTTCACTGTG ACTGACCTTA CACCCATGGA GATCGTAGTG
GATATTTTCC GAAAGCTGGG ACTGCGGCAG TGCCTGGTTA CACACAACGG GCGATTGCTT
GGAATCATTA CCAAAAAGGA TGTGTTAAAG CATATAGCAC AGATGGCGAA CCAAGATCCT
GATTCCATTC TCTTCAACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001269092.1
CDS232..2532
Misc Feature(1)226..228(+)
Misc Feature(2)505..2001(+)
Misc Feature(3)790..1965(+)
Misc Feature(4)922..924(+)
Misc Feature(5)1093..1095(+)
Misc Feature(6)2038..2478(+)
Misc Feature(7)2074..2484(+)
Exon (1)1..244
Gene:CLCN5
Gene Synonym:
Exon (2)245..396
Gene:CLCN5
Gene Synonym:
Exon (3)397..496
Gene:CLCN5
Gene Synonym:
Exon (4)497..684
Gene:CLCN5
Gene Synonym:
Exon (5)685..807
Gene:CLCN5
Gene Synonym:
Exon (6)808..1014
Gene:CLCN5
Gene Synonym:
Exon (7)1015..1095
Gene:CLCN5
Gene Synonym:
Exon (8)1096..1638
Gene:CLCN5
Gene Synonym:
Exon (9)1639..1825
Gene:CLCN5
Gene Synonym:
Exon (10)1826..2224
Gene:CLCN5
Gene Synonym:
Exon (11)2225..2441
Gene:CLCN5
Gene Synonym:
Exon (12)2442..9548
Gene:CLCN5
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001282163
Organism Homo sapiens (human)
Definition Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001282163

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGTTCCTAC CAGAGGACAA GTCGTACAAT GGTGGAGGAA TAGGTTCTTC AAATAGGATC 
ATGGACTTCT TGGAGGAGCC AATCCCTGGT GTAGGGACCT ATGATGATTT CAATACAATT
GATTGGGTGA GAGAGAAGTC TCGAGACCGG GATAGGCACC GAGAGATTAC CAATAAAAGC
AAAGAGTCAA CATGGGCCTT AATTCACAGT GTGAGTGATG CTTTTTCCGG CTGGTTGTTG
ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG TTAGCTGGTT TGATAGACAT CTCTGCTCAT
TGGATGACAG ACTTAAAAGA AGGTATATGC ACAGGGGGAT TCTGGTTTAA CCATGAACAT
TGTTGCTGGA ACTCTGAGCA TGTCACCTTT GAAGAGAGAG ACAAATGTCC AGAGTGGAAT
AGTTGGTCCC AGCTTATCAT CAGCACAGAT GAGGGAGCCT TTGCCTACAT AGTCAATTAT
TTCATGTACG TCCTCTGGGC TCTCCTATTT GCCTTCCTTG CCGTATCTCT TGTCAAGGTG
TTTGCGCCTT ATGCCTGTGG CTCTGGAATC CCTGAGATAA AAACTATCTT GAGTGGTTTC
ATTATTAGGG GCTATTTGGG TAAGTGGACT CTGGTTATCA AAACCATCAC CTTGGTGCTG
GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA GAGGGCCCTC TAGTGCACGT GGCTTGCTGC
TGTGGGAACA TCCTGTGCCA CTGCTTCAAC AAATACAGGA AGAATGAAGC CAAGCGCAGA
GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT GTATCTGTAG CCTTTGGAGC ACCTATAGGT
GGAGTATTAT TCAGCCTTGA AGAGGTCAGC TACTATTTTC CCCTCAAAAC ATTGTGGCGT
TCATTCTTTG CTGCCTTGGT GGCAGCATTC ACTCTACGCT CCATCAATCC ATTTGGGAAC
AGCCGCCTGG TACTATTTTA TGTGGAGTTT CACACCCCAT GGCATCTCTT TGAGCTCGTG
CCATTCATTC TGCTGGGCAT ATTTGGTGGT CTGTGGGGAG CACTGTTTAT CCGCACAAAC
ATTGCCTGGT GTCGGAAGCG AAAGACCACC CAGTTGGGCA AGTATCCTGT TATAGAGGTA
CTCGTCGTGA CAGCCATCAC TGCCATCCTG GCTTTCCCCA ATGAATACAC TCGGATGAGC
ACAAGTGAGC TCATTTCTGA GCTGTTTAAT GACTGTGGCC TTCTGGACTC CTCCAAGCTC
TGTGATTATG AGAACCGTTT CAACACAAGC AAAGGGGGTG AACTGCCTGA CAGACCGGCT
GGCGTGGGAG TCTACAGTGC AATGTGGCAG CTGGCTTTAA CACTCATACT GAAAATTGTC
ATTACTATAT TCACCTTTGG CATGAAGATC CCTTCTGGCC TCTTTATCCC TAGCATGGCT
GTTGGTGCTA TAGCAGGTCG ACTTCTAGGA GTAGGAATGG AACAGCTGGC TTATTACCAC
CAGGAATGGA CCGTCTTCAA TAGCTGGTGT AGTCAGGGAG CTGATTGCAT CACCCCCGGC
CTTTATGCAA TGGTTGGGGC TGCAGCCTGC TTAGGTGGGG TGACTCGGAT GACTGTTTCT
CTTGTTGTCA TAATGTTTGA ACTGACTGGT GGCTTAGAAT ACATCGTGCC TCTGATGGCT
GCAGCCATGA CAAGCAAGTG GGTGGCAGAT GCTCTTGGGC GGGAGGGCAT CTATGATGCC
CACATCCGTC TCAATGGATA CCCCTTTCTT GAAGCCAAAG AAGAGTTTGC TCATAAGACC
CTGGCAATGG ATGTGATGAA ACCCCGGAGA AATGATCCTT TGTTGACTGT CCTTACTCAG
GACAGTATGA CTGTGGAAGA TGTAGAGACC ATAATCAGTG AAACCACTTA CAGTGGCTTC
CCAGTGGTGG TATCCCGGGA GTCCCAAAGA CTTGTGGGCT TTGTCCTCCG AAGAGATCTC
ATTATTTCAA TTGAAAATGC TCGAAAGAAA CAGGATGGGG TTGTTAGCAC TTCCATCATT
TATTTCACGG AGCATTCTCC TCCATTGCCA CCATACACTC CACCCACTCT AAAGCTTCGG
AACATCCTCG ATCTCAGCCC CTTCACTGTG ACTGACCTTA CACCCATGGA GATCGTAGTG
GATATTTTCC GAAAGCTGGG ACTGCGGCAG TGCCTGGTTA CACACAACGG GCGATTGCTT
GGAATCATTA CCAAAAAGGA TGTGTTAAAG CATATAGCAC AGATGGCGAA CCAAGATCCT
GATTCCATTC TCTTCAACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu56926
Clone ID Related Accession (Same CDS sequence) XM_011543888
Accession Version XM_011543888.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2523bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product H(+)/Cl(-) exchange transporter 5 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_079573.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
ATGGCCATGT GGCAGGGTGC CATGGATAAC AGAGGCTTTC AGCAGGGGAG TTTTAGTAGC 
TTCCAGAACA GCTCCAGTGA TGAAGACCTG ATGGACATTC CAGCAACCGC TATGGATTTC
TCCATGAGAG ATGATGTTCC TCCCTTAGAC CGAGAAGTAG GAGAGGACAA GTCGTACAAT
GGTGGAGGAA TAGGTTCTTC AAATAGGATC ATGGACTTCT TGGAGGAGCC AATCCCTGGT
GTAGGGACCT ATGATGATTT CAATACAATT GATTGGGTGA GAGAGAAGTC TCGAGACCGG
GATAGGCACC GAGAGATTAC CAATAAAAGC AAAGAGTCAA CATGGGCCTT AATTCACAGT
GTGAGTGATG CTTTTTCCGG CTGGTTGTTG ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG
TTAGCTGGTT TGATAGACAT CTCTGCTCAT TGGATGACAG ACTTAAAAGA AGGTATATGC
ACAGGGGGAT TCTGGTTTAA CCATGAACAT TGTTGCTGGA ACTCTGAGCA TGTCACCTTT
GAAGAGAGAG ACAAATGTCC AGAGTGGAAT AGTTGGTCCC AGCTTATCAT CAGCACAGAT
GAGGGAGCCT TTGCCTACAT AGTCAATTAT TTCATGTACG TCCTCTGGGC TCTCCTATTT
GCCTTCCTTG CCGTATCTCT TGTCAAGGTG TTTGCGCCTT ATGCCTGTGG CTCTGGAATC
CCTGAGATAA AAACTATCTT GAGTGGTTTC ATTATTAGGG GCTATTTGGG TAAGTGGACT
CTGGTTATCA AAACCATCAC CTTGGTGCTG GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA
GAGGGCCCTC TAGTGCACGT GGCTTGCTGC TGTGGGAACA TCCTGTGCCA CTGCTTCAAC
AAATACAGGA AGAATGAAGC CAAGCGCAGA GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT
GTATCTGTAG CCTTTGGAGC ACCTATAGGT GGAGTATTAT TCAGCCTTGA AGAGGTCAGC
TACTATTTTC CCCTCAAAAC ATTGTGGCGT TCATTCTTTG CTGCCTTGGT GGCAGCATTC
ACTCTACGCT CCATCAATCC ATTTGGGAAC AGCCGCCTGG TACTATTTTA TGTGGAGTTT
CACACCCCAT GGCATCTCTT TGAGCTCGTG CCATTCATTC TGCTGGGCAT ATTTGGTGGT
CTGTGGGGAG CACTGTTTAT CCGCACAAAC ATTGCCTGGT GTCGGAAGCG AAAGACCACC
CAGTTGGGCA AGTATCCTGT TATAGAGGTA CTCGTCGTGA CAGCCATCAC TGCCATCCTG
GCTTTCCCCA ATGAATACAC TCGGATGAGC ACAAGTGAGC TCATTTCTGA GCTGTTTAAT
GACTGTGGCC TTCTGGACTC CTCCAAGCTC TGTGATTATG AGAACCGTTT CAACACAAGC
AAAGGGGGTG AACTGCCTGA CAGACCGGCT GGCGTGGGAG TCTACAGTGC AATGTGGCAG
CTGGCTTTAA CACTCATACT GAAAATTGTC ATTACTATAT TCACCTTTGG CATGAAGGCC
CAATTTCTGC CTCCAGTTCT GTGTTGGTCT GGAGAGTTCA GGCTCTTGCC TGATGGACCC
CGAATCAGGA TCCCTTCTGG CCTCTTTATC CCTAGCATGG CTGTTGGTGC TATAGCAGGT
CGACTTCTAG GAGTAGGAAT GGAACAGCTG GCTTATTACC ACCAGGAATG GACCGTCTTC
AATAGCTGGT GTAGTCAGGG AGCTGATTGC ATCACCCCCG GCCTTTATGC AATGGTTGGG
GCTGCAGCCT GCTTAGGTGG GGTGACTCGG ATGACTGTTT CTCTTGTTGT CATAATGTTT
GAACTGACTG GTGGCTTAGA ATACATCGTG CCTCTGATGG CTGCAGCCAT GACAAGCAAG
TGGGTGGCAG ATGCTCTTGG GCGGGAGGGC ATCTATGATG CCCACATCCG TCTCAATGGA
TACCCCTTTC TTGAAGCCAA AGAAGAGTTT GCTCATAAGA CCCTGGCAAT GGATGTGATG
AAACCCCGGA GAAATGATCC TTTGTTGACT GTCCTTACTC AGGACAGTAT GACTGTGGAA
GATGTAGAGA CCATAATCAG TGAAACCACT TACAGTGGCT TCCCAGTGGT GGTATCCCGG
GAGTCCCAAA GACTTGTGGG CTTTGTCCTC CGAAGAGATC TCATTATTTC AATTGAAAAT
GCTCGAAAGA AACAGGATGG GGTTGTTAGC ACTTCCATCA TTTATTTCAC GGAGCATTCT
CCTCCATTGC CACCATACAC TCCACCCACT CTAAAGCTTC GGAACATCCT CGATCTCAGC
CCCTTCACTG TGACTGACCT TACACCCATG GAGATCGTAG TGGATATTTT CCGAAAGCTG
GGACTGCGGC AGTGCCTGGT TACACACAAC GGGCGATTGC TTGGAATCAT TACCAAAAAG
GATGTGTTAA AGCATATAGC ACAGATGGCG AACCAAGATC CTGATTCCAT TCTCTTCAAC
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011542190.1
CDS333..2855
Misc Feature(1)756..2324(+)
Misc Feature(2)1041..2288(+)
Misc Feature(3)1173..1175(+)
Misc Feature(4)1344..1346(+)
Misc Feature(5)2361..2801(+)
Misc Feature(6)2397..2807(+)
Translation

Target ORF information:

RefSeq Version XM_011543888
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011543888

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
ATGGCCATGT GGCAGGGTGC CATGGATAAC AGAGGCTTTC AGCAGGGGAG TTTTAGTAGC 
TTCCAGAACA GCTCCAGTGA TGAAGACCTG ATGGACATTC CAGCAACCGC TATGGATTTC
TCCATGAGAG ATGATGTTCC TCCCTTAGAC CGAGAAGTAG GAGAGGACAA GTCGTACAAT
GGTGGAGGAA TAGGTTCTTC AAATAGGATC ATGGACTTCT TGGAGGAGCC AATCCCTGGT
GTAGGGACCT ATGATGATTT CAATACAATT GATTGGGTGA GAGAGAAGTC TCGAGACCGG
GATAGGCACC GAGAGATTAC CAATAAAAGC AAAGAGTCAA CATGGGCCTT AATTCACAGT
GTGAGTGATG CTTTTTCCGG CTGGTTGTTG ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG
TTAGCTGGTT TGATAGACAT CTCTGCTCAT TGGATGACAG ACTTAAAAGA AGGTATATGC
ACAGGGGGAT TCTGGTTTAA CCATGAACAT TGTTGCTGGA ACTCTGAGCA TGTCACCTTT
GAAGAGAGAG ACAAATGTCC AGAGTGGAAT AGTTGGTCCC AGCTTATCAT CAGCACAGAT
GAGGGAGCCT TTGCCTACAT AGTCAATTAT TTCATGTACG TCCTCTGGGC TCTCCTATTT
GCCTTCCTTG CCGTATCTCT TGTCAAGGTG TTTGCGCCTT ATGCCTGTGG CTCTGGAATC
CCTGAGATAA AAACTATCTT GAGTGGTTTC ATTATTAGGG GCTATTTGGG TAAGTGGACT
CTGGTTATCA AAACCATCAC CTTGGTGCTG GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA
GAGGGCCCTC TAGTGCACGT GGCTTGCTGC TGTGGGAACA TCCTGTGCCA CTGCTTCAAC
AAATACAGGA AGAATGAAGC CAAGCGCAGA GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT
GTATCTGTAG CCTTTGGAGC ACCTATAGGT GGAGTATTAT TCAGCCTTGA AGAGGTCAGC
TACTATTTTC CCCTCAAAAC ATTGTGGCGT TCATTCTTTG CTGCCTTGGT GGCAGCATTC
ACTCTACGCT CCATCAATCC ATTTGGGAAC AGCCGCCTGG TACTATTTTA TGTGGAGTTT
CACACCCCAT GGCATCTCTT TGAGCTCGTG CCATTCATTC TGCTGGGCAT ATTTGGTGGT
CTGTGGGGAG CACTGTTTAT CCGCACAAAC ATTGCCTGGT GTCGGAAGCG AAAGACCACC
CAGTTGGGCA AGTATCCTGT TATAGAGGTA CTCGTCGTGA CAGCCATCAC TGCCATCCTG
GCTTTCCCCA ATGAATACAC TCGGATGAGC ACAAGTGAGC TCATTTCTGA GCTGTTTAAT
GACTGTGGCC TTCTGGACTC CTCCAAGCTC TGTGATTATG AGAACCGTTT CAACACAAGC
AAAGGGGGTG AACTGCCTGA CAGACCGGCT GGCGTGGGAG TCTACAGTGC AATGTGGCAG
CTGGCTTTAA CACTCATACT GAAAATTGTC ATTACTATAT TCACCTTTGG CATGAAGGCC
CAATTTCTGC CTCCAGTTCT GTGTTGGTCT GGAGAGTTCA GGCTCTTGCC TGATGGACCC
CGAATCAGGA TCCCTTCTGG CCTCTTTATC CCTAGCATGG CTGTTGGTGC TATAGCAGGT
CGACTTCTAG GAGTAGGAAT GGAACAGCTG GCTTATTACC ACCAGGAATG GACCGTCTTC
AATAGCTGGT GTAGTCAGGG AGCTGATTGC ATCACCCCCG GCCTTTATGC AATGGTTGGG
GCTGCAGCCT GCTTAGGTGG GGTGACTCGG ATGACTGTTT CTCTTGTTGT CATAATGTTT
GAACTGACTG GTGGCTTAGA ATACATCGTG CCTCTGATGG CTGCAGCCAT GACAAGCAAG
TGGGTGGCAG ATGCTCTTGG GCGGGAGGGC ATCTATGATG CCCACATCCG TCTCAATGGA
TACCCCTTTC TTGAAGCCAA AGAAGAGTTT GCTCATAAGA CCCTGGCAAT GGATGTGATG
AAACCCCGGA GAAATGATCC TTTGTTGACT GTCCTTACTC AGGACAGTAT GACTGTGGAA
GATGTAGAGA CCATAATCAG TGAAACCACT TACAGTGGCT TCCCAGTGGT GGTATCCCGG
GAGTCCCAAA GACTTGTGGG CTTTGTCCTC CGAAGAGATC TCATTATTTC AATTGAAAAT
GCTCGAAAGA AACAGGATGG GGTTGTTAGC ACTTCCATCA TTTATTTCAC GGAGCATTCT
CCTCCATTGC CACCATACAC TCCACCCACT CTAAAGCTTC GGAACATCCT CGATCTCAGC
CCCTTCACTG TGACTGACCT TACACCCATG GAGATCGTAG TGGATATTTT CCGAAAGCTG
GGACTGCGGC AGTGCCTGGT TACACACAAC GGGCGATTGC TTGGAATCAT TACCAAAAAG
GATGTGTTAA AGCATATAGC ACAGATGGCG AACCAAGATC CTGATTCCAT TCTCTTCAAC
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu56927
Clone ID Related Accession (Same CDS sequence) XM_011543889
Accession Version XM_011543889.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2313bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product H(+)/Cl(-) exchange transporter 5 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_079573.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGGACTTCT TGGAGGAGCC AATCCCTGGT GTAGGGACCT ATGATGATTT CAATACAATT 
GATTGGGTGA GAGAGAAGTC TCGAGACCGG GATAGGCACC GAGAGATTAC CAATAAAAGC
AAAGAGTCAA CATGGGCCTT AATTCACAGT GTGAGTGATG CTTTTTCCGG CTGGTTGTTG
ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG TTAGCTGGTT TGATAGACAT CTCTGCTCAT
TGGATGACAG ACTTAAAAGA AGGTATATGC ACAGGGGGAT TCTGGTTTAA CCATGAACAT
TGTTGCTGGA ACTCTGAGCA TGTCACCTTT GAAGAGAGAG ACAAATGTCC AGAGTGGAAT
AGTTGGTCCC AGCTTATCAT CAGCACAGAT GAGGGAGCCT TTGCCTACAT AGTCAATTAT
TTCATGTACG TCCTCTGGGC TCTCCTATTT GCCTTCCTTG CCGTATCTCT TGTCAAGGTG
TTTGCGCCTT ATGCCTGTGG CTCTGGAATC CCTGAGATAA AAACTATCTT GAGTGGTTTC
ATTATTAGGG GCTATTTGGG TAAGTGGACT CTGGTTATCA AAACCATCAC CTTGGTGCTG
GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA GAGGGCCCTC TAGTGCACGT GGCTTGCTGC
TGTGGGAACA TCCTGTGCCA CTGCTTCAAC AAATACAGGA AGAATGAAGC CAAGCGCAGA
GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT GTATCTGTAG CCTTTGGAGC ACCTATAGGT
GGAGTATTAT TCAGCCTTGA AGAGGTCAGC TACTATTTTC CCCTCAAAAC ATTGTGGCGT
TCATTCTTTG CTGCCTTGGT GGCAGCATTC ACTCTACGCT CCATCAATCC ATTTGGGAAC
AGCCGCCTGG TACTATTTTA TGTGGAGTTT CACACCCCAT GGCATCTCTT TGAGCTCGTG
CCATTCATTC TGCTGGGCAT ATTTGGTGGT CTGTGGGGAG CACTGTTTAT CCGCACAAAC
ATTGCCTGGT GTCGGAAGCG AAAGACCACC CAGTTGGGCA AGTATCCTGT TATAGAGGTA
CTCGTCGTGA CAGCCATCAC TGCCATCCTG GCTTTCCCCA ATGAATACAC TCGGATGAGC
ACAAGTGAGC TCATTTCTGA GCTGTTTAAT GACTGTGGCC TTCTGGACTC CTCCAAGCTC
TGTGATTATG AGAACCGTTT CAACACAAGC AAAGGGGGTG AACTGCCTGA CAGACCGGCT
GGCGTGGGAG TCTACAGTGC AATGTGGCAG CTGGCTTTAA CACTCATACT GAAAATTGTC
ATTACTATAT TCACCTTTGG CATGAAGGCC CAATTTCTGC CTCCAGTTCT GTGTTGGTCT
GGAGAGTTCA GGCTCTTGCC TGATGGACCC CGAATCAGGA TCCCTTCTGG CCTCTTTATC
CCTAGCATGG CTGTTGGTGC TATAGCAGGT CGACTTCTAG GAGTAGGAAT GGAACAGCTG
GCTTATTACC ACCAGGAATG GACCGTCTTC AATAGCTGGT GTAGTCAGGG AGCTGATTGC
ATCACCCCCG GCCTTTATGC AATGGTTGGG GCTGCAGCCT GCTTAGGTGG GGTGACTCGG
ATGACTGTTT CTCTTGTTGT CATAATGTTT GAACTGACTG GTGGCTTAGA ATACATCGTG
CCTCTGATGG CTGCAGCCAT GACAAGCAAG TGGGTGGCAG ATGCTCTTGG GCGGGAGGGC
ATCTATGATG CCCACATCCG TCTCAATGGA TACCCCTTTC TTGAAGCCAA AGAAGAGTTT
GCTCATAAGA CCCTGGCAAT GGATGTGATG AAACCCCGGA GAAATGATCC TTTGTTGACT
GTCCTTACTC AGGACAGTAT GACTGTGGAA GATGTAGAGA CCATAATCAG TGAAACCACT
TACAGTGGCT TCCCAGTGGT GGTATCCCGG GAGTCCCAAA GACTTGTGGG CTTTGTCCTC
CGAAGAGATC TCATTATTTC AATTGAAAAT GCTCGAAAGA AACAGGATGG GGTTGTTAGC
ACTTCCATCA TTTATTTCAC GGAGCATTCT CCTCCATTGC CACCATACAC TCCACCCACT
CTAAAGCTTC GGAACATCCT CGATCTCAGC CCCTTCACTG TGACTGACCT TACACCCATG
GAGATCGTAG TGGATATTTT CCGAAAGCTG GGACTGCGGC AGTGCCTGGT TACACACAAC
GGGCGATTGC TTGGAATCAT TACCAAAAAG GATGTGTTAA AGCATATAGC ACAGATGGCG
AACCAAGATC CTGATTCCAT TCTCTTCAAC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011542191.1
CDS248..2560
Misc Feature(1)461..2029(+)
Misc Feature(2)746..1993(+)
Misc Feature(3)878..880(+)
Misc Feature(4)1049..1051(+)
Misc Feature(5)2066..2506(+)
Misc Feature(6)2102..2512(+)
Translation

Target ORF information:

RefSeq Version XM_011543889
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011543889

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGGACTTCT TGGAGGAGCC AATCCCTGGT GTAGGGACCT ATGATGATTT CAATACAATT 
GATTGGGTGA GAGAGAAGTC TCGAGACCGG GATAGGCACC GAGAGATTAC CAATAAAAGC
AAAGAGTCAA CATGGGCCTT AATTCACAGT GTGAGTGATG CTTTTTCCGG CTGGTTGTTG
ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG TTAGCTGGTT TGATAGACAT CTCTGCTCAT
TGGATGACAG ACTTAAAAGA AGGTATATGC ACAGGGGGAT TCTGGTTTAA CCATGAACAT
TGTTGCTGGA ACTCTGAGCA TGTCACCTTT GAAGAGAGAG ACAAATGTCC AGAGTGGAAT
AGTTGGTCCC AGCTTATCAT CAGCACAGAT GAGGGAGCCT TTGCCTACAT AGTCAATTAT
TTCATGTACG TCCTCTGGGC TCTCCTATTT GCCTTCCTTG CCGTATCTCT TGTCAAGGTG
TTTGCGCCTT ATGCCTGTGG CTCTGGAATC CCTGAGATAA AAACTATCTT GAGTGGTTTC
ATTATTAGGG GCTATTTGGG TAAGTGGACT CTGGTTATCA AAACCATCAC CTTGGTGCTG
GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA GAGGGCCCTC TAGTGCACGT GGCTTGCTGC
TGTGGGAACA TCCTGTGCCA CTGCTTCAAC AAATACAGGA AGAATGAAGC CAAGCGCAGA
GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT GTATCTGTAG CCTTTGGAGC ACCTATAGGT
GGAGTATTAT TCAGCCTTGA AGAGGTCAGC TACTATTTTC CCCTCAAAAC ATTGTGGCGT
TCATTCTTTG CTGCCTTGGT GGCAGCATTC ACTCTACGCT CCATCAATCC ATTTGGGAAC
AGCCGCCTGG TACTATTTTA TGTGGAGTTT CACACCCCAT GGCATCTCTT TGAGCTCGTG
CCATTCATTC TGCTGGGCAT ATTTGGTGGT CTGTGGGGAG CACTGTTTAT CCGCACAAAC
ATTGCCTGGT GTCGGAAGCG AAAGACCACC CAGTTGGGCA AGTATCCTGT TATAGAGGTA
CTCGTCGTGA CAGCCATCAC TGCCATCCTG GCTTTCCCCA ATGAATACAC TCGGATGAGC
ACAAGTGAGC TCATTTCTGA GCTGTTTAAT GACTGTGGCC TTCTGGACTC CTCCAAGCTC
TGTGATTATG AGAACCGTTT CAACACAAGC AAAGGGGGTG AACTGCCTGA CAGACCGGCT
GGCGTGGGAG TCTACAGTGC AATGTGGCAG CTGGCTTTAA CACTCATACT GAAAATTGTC
ATTACTATAT TCACCTTTGG CATGAAGGCC CAATTTCTGC CTCCAGTTCT GTGTTGGTCT
GGAGAGTTCA GGCTCTTGCC TGATGGACCC CGAATCAGGA TCCCTTCTGG CCTCTTTATC
CCTAGCATGG CTGTTGGTGC TATAGCAGGT CGACTTCTAG GAGTAGGAAT GGAACAGCTG
GCTTATTACC ACCAGGAATG GACCGTCTTC AATAGCTGGT GTAGTCAGGG AGCTGATTGC
ATCACCCCCG GCCTTTATGC AATGGTTGGG GCTGCAGCCT GCTTAGGTGG GGTGACTCGG
ATGACTGTTT CTCTTGTTGT CATAATGTTT GAACTGACTG GTGGCTTAGA ATACATCGTG
CCTCTGATGG CTGCAGCCAT GACAAGCAAG TGGGTGGCAG ATGCTCTTGG GCGGGAGGGC
ATCTATGATG CCCACATCCG TCTCAATGGA TACCCCTTTC TTGAAGCCAA AGAAGAGTTT
GCTCATAAGA CCCTGGCAAT GGATGTGATG AAACCCCGGA GAAATGATCC TTTGTTGACT
GTCCTTACTC AGGACAGTAT GACTGTGGAA GATGTAGAGA CCATAATCAG TGAAACCACT
TACAGTGGCT TCCCAGTGGT GGTATCCCGG GAGTCCCAAA GACTTGTGGG CTTTGTCCTC
CGAAGAGATC TCATTATTTC AATTGAAAAT GCTCGAAAGA AACAGGATGG GGTTGTTAGC
ACTTCCATCA TTTATTTCAC GGAGCATTCT CCTCCATTGC CACCATACAC TCCACCCACT
CTAAAGCTTC GGAACATCCT CGATCTCAGC CCCTTCACTG TGACTGACCT TACACCCATG
GAGATCGTAG TGGATATTTT CCGAAAGCTG GGACTGCGGC AGTGCCTGGT TACACACAAC
GGGCGATTGC TTGGAATCAT TACCAAAAAG GATGTGTTAA AGCATATAGC ACAGATGGCG
AACCAAGATC CTGATTCCAT TCTCTTCAAC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21666
Clone ID Related Accession (Same CDS sequence) NM_001127898 , NM_001127899
Accession Version NM_001127899.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2451bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product H(+)/Cl(-) exchange transporter 5 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BK000969.1, DA737534.1, AK092049.1, AC231645.2, BC051691.1, AK025562.1 and AA743724.1. This sequence is a reference standard in the RefSeqGene project. On Aug 21, 2013 this sequence version replaced gi:442535511. Transcript Variant: This variant (1, also known as type 2) represents the longest transcript and encodes the longest isoform (a). Both variants 1 and 2 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK092049.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGCCATGT GGCAGGGTGC CATGGATAAC AGAGGCTTTC AGCAGGGGAG TTTTAGTAGC 
TTCCAGAACA GCTCCAGTGA TGAAGACCTG ATGGACATTC CAGCAACCGC TATGGATTTC
TCCATGAGAG ATGATGTTCC TCCCTTAGAC CGAGAAGTAG GAGAGGACAA GTCGTACAAT
GGTGGAGGAA TAGGTTCTTC AAATAGGATC ATGGACTTCT TGGAGGAGCC AATCCCTGGT
GTAGGGACCT ATGATGATTT CAATACAATT GATTGGGTGA GAGAGAAGTC TCGAGACCGG
GATAGGCACC GAGAGATTAC CAATAAAAGC AAAGAGTCAA CATGGGCCTT AATTCACAGT
GTGAGTGATG CTTTTTCCGG CTGGTTGTTG ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG
TTAGCTGGTT TGATAGACAT CTCTGCTCAT TGGATGACAG ACTTAAAAGA AGGTATATGC
ACAGGGGGAT TCTGGTTTAA CCATGAACAT TGTTGCTGGA ACTCTGAGCA TGTCACCTTT
GAAGAGAGAG ACAAATGTCC AGAGTGGAAT AGTTGGTCCC AGCTTATCAT CAGCACAGAT
GAGGGAGCCT TTGCCTACAT AGTCAATTAT TTCATGTACG TCCTCTGGGC TCTCCTATTT
GCCTTCCTTG CCGTATCTCT TGTCAAGGTG TTTGCGCCTT ATGCCTGTGG CTCTGGAATC
CCTGAGATAA AAACTATCTT GAGTGGTTTC ATTATTAGGG GCTATTTGGG TAAGTGGACT
CTGGTTATCA AAACCATCAC CTTGGTGCTG GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA
GAGGGCCCTC TAGTGCACGT GGCTTGCTGC TGTGGGAACA TCCTGTGCCA CTGCTTCAAC
AAATACAGGA AGAATGAAGC CAAGCGCAGA GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT
GTATCTGTAG CCTTTGGAGC ACCTATAGGT GGAGTATTAT TCAGCCTTGA AGAGGTCAGC
TACTATTTTC CCCTCAAAAC ATTGTGGCGT TCATTCTTTG CTGCCTTGGT GGCAGCATTC
ACTCTACGCT CCATCAATCC ATTTGGGAAC AGCCGCCTGG TACTATTTTA TGTGGAGTTT
CACACCCCAT GGCATCTCTT TGAGCTCGTG CCATTCATTC TGCTGGGCAT ATTTGGTGGT
CTGTGGGGAG CACTGTTTAT CCGCACAAAC ATTGCCTGGT GTCGGAAGCG AAAGACCACC
CAGTTGGGCA AGTATCCTGT TATAGAGGTA CTCGTCGTGA CAGCCATCAC TGCCATCCTG
GCTTTCCCCA ATGAATACAC TCGGATGAGC ACAAGTGAGC TCATTTCTGA GCTGTTTAAT
GACTGTGGCC TTCTGGACTC CTCCAAGCTC TGTGATTATG AGAACCGTTT CAACACAAGC
AAAGGGGGTG AACTGCCTGA CAGACCGGCT GGCGTGGGAG TCTACAGTGC AATGTGGCAG
CTGGCTTTAA CACTCATACT GAAAATTGTC ATTACTATAT TCACCTTTGG CATGAAGATC
CCTTCTGGCC TCTTTATCCC TAGCATGGCT GTTGGTGCTA TAGCAGGTCG ACTTCTAGGA
GTAGGAATGG AACAGCTGGC TTATTACCAC CAGGAATGGA CCGTCTTCAA TAGCTGGTGT
AGTCAGGGAG CTGATTGCAT CACCCCCGGC CTTTATGCAA TGGTTGGGGC TGCAGCCTGC
TTAGGTGGGG TGACTCGGAT GACTGTTTCT CTTGTTGTCA TAATGTTTGA ACTGACTGGT
GGCTTAGAAT ACATCGTGCC TCTGATGGCT GCAGCCATGA CAAGCAAGTG GGTGGCAGAT
GCTCTTGGGC GGGAGGGCAT CTATGATGCC CACATCCGTC TCAATGGATA CCCCTTTCTT
GAAGCCAAAG AAGAGTTTGC TCATAAGACC CTGGCAATGG ATGTGATGAA ACCCCGGAGA
AATGATCCTT TGTTGACTGT CCTTACTCAG GACAGTATGA CTGTGGAAGA TGTAGAGACC
ATAATCAGTG AAACCACTTA CAGTGGCTTC CCAGTGGTGG TATCCCGGGA GTCCCAAAGA
CTTGTGGGCT TTGTCCTCCG AAGAGATCTC ATTATTTCAA TTGAAAATGC TCGAAAGAAA
CAGGATGGGG TTGTTAGCAC TTCCATCATT TATTTCACGG AGCATTCTCC TCCATTGCCA
CCATACACTC CACCCACTCT AAAGCTTCGG AACATCCTCG ATCTCAGCCC CTTCACTGTG
ACTGACCTTA CACCCATGGA GATCGTAGTG GATATTTTCC GAAAGCTGGG ACTGCGGCAG
TGCCTGGTTA CACACAACGG GCGATTGCTT GGAATCATTA CCAAAAAGGA TGTGTTAAAG
CATATAGCAC AGATGGCGAA CCAAGATCCT GATTCCATTC TCTTCAACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001121371.1
CDS642..3092
Misc Feature(1)585..587(+)
Misc Feature(2)1065..2561(+)
Misc Feature(3)1350..2525(+)
Misc Feature(4)1482..1484(+)
Misc Feature(5)1653..1655(+)
Misc Feature(6)2598..3038(+)
Misc Feature(7)2634..3044(+)
Exon (1)1..178
Gene:CLCN5
Gene Synonym:
Exon (2)179..513
Gene:CLCN5
Gene Synonym:
Exon (3)514..657
Gene:CLCN5
Gene Synonym:
Exon (4)658..804
Gene:CLCN5
Gene Synonym:
Exon (5)805..956
Gene:CLCN5
Gene Synonym:
Exon (6)957..1056
Gene:CLCN5
Gene Synonym:
Exon (7)1057..1244
Gene:CLCN5
Gene Synonym:
Exon (8)1245..1367
Gene:CLCN5
Gene Synonym:
Exon (9)1368..1574
Gene:CLCN5
Gene Synonym:
Exon (10)1575..1655
Gene:CLCN5
Gene Synonym:
Exon (11)1656..2198
Gene:CLCN5
Gene Synonym:
Exon (12)2199..2385
Gene:CLCN5
Gene Synonym:
Exon (13)2386..2784
Gene:CLCN5
Gene Synonym:
Exon (14)2785..3001
Gene:CLCN5
Gene Synonym:
Exon (15)3002..10108
Gene:CLCN5
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001127899
Organism Homo sapiens (human)
Definition Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127899

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGCCATGT GGCAGGGTGC CATGGATAAC AGAGGCTTTC AGCAGGGGAG TTTTAGTAGC 
TTCCAGAACA GCTCCAGTGA TGAAGACCTG ATGGACATTC CAGCAACCGC TATGGATTTC
TCCATGAGAG ATGATGTTCC TCCCTTAGAC CGAGAAGTAG GAGAGGACAA GTCGTACAAT
GGTGGAGGAA TAGGTTCTTC AAATAGGATC ATGGACTTCT TGGAGGAGCC AATCCCTGGT
GTAGGGACCT ATGATGATTT CAATACAATT GATTGGGTGA GAGAGAAGTC TCGAGACCGG
GATAGGCACC GAGAGATTAC CAATAAAAGC AAAGAGTCAA CATGGGCCTT AATTCACAGT
GTGAGTGATG CTTTTTCCGG CTGGTTGTTG ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG
TTAGCTGGTT TGATAGACAT CTCTGCTCAT TGGATGACAG ACTTAAAAGA AGGTATATGC
ACAGGGGGAT TCTGGTTTAA CCATGAACAT TGTTGCTGGA ACTCTGAGCA TGTCACCTTT
GAAGAGAGAG ACAAATGTCC AGAGTGGAAT AGTTGGTCCC AGCTTATCAT CAGCACAGAT
GAGGGAGCCT TTGCCTACAT AGTCAATTAT TTCATGTACG TCCTCTGGGC TCTCCTATTT
GCCTTCCTTG CCGTATCTCT TGTCAAGGTG TTTGCGCCTT ATGCCTGTGG CTCTGGAATC
CCTGAGATAA AAACTATCTT GAGTGGTTTC ATTATTAGGG GCTATTTGGG TAAGTGGACT
CTGGTTATCA AAACCATCAC CTTGGTGCTG GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA
GAGGGCCCTC TAGTGCACGT GGCTTGCTGC TGTGGGAACA TCCTGTGCCA CTGCTTCAAC
AAATACAGGA AGAATGAAGC CAAGCGCAGA GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT
GTATCTGTAG CCTTTGGAGC ACCTATAGGT GGAGTATTAT TCAGCCTTGA AGAGGTCAGC
TACTATTTTC CCCTCAAAAC ATTGTGGCGT TCATTCTTTG CTGCCTTGGT GGCAGCATTC
ACTCTACGCT CCATCAATCC ATTTGGGAAC AGCCGCCTGG TACTATTTTA TGTGGAGTTT
CACACCCCAT GGCATCTCTT TGAGCTCGTG CCATTCATTC TGCTGGGCAT ATTTGGTGGT
CTGTGGGGAG CACTGTTTAT CCGCACAAAC ATTGCCTGGT GTCGGAAGCG AAAGACCACC
CAGTTGGGCA AGTATCCTGT TATAGAGGTA CTCGTCGTGA CAGCCATCAC TGCCATCCTG
GCTTTCCCCA ATGAATACAC TCGGATGAGC ACAAGTGAGC TCATTTCTGA GCTGTTTAAT
GACTGTGGCC TTCTGGACTC CTCCAAGCTC TGTGATTATG AGAACCGTTT CAACACAAGC
AAAGGGGGTG AACTGCCTGA CAGACCGGCT GGCGTGGGAG TCTACAGTGC AATGTGGCAG
CTGGCTTTAA CACTCATACT GAAAATTGTC ATTACTATAT TCACCTTTGG CATGAAGATC
CCTTCTGGCC TCTTTATCCC TAGCATGGCT GTTGGTGCTA TAGCAGGTCG ACTTCTAGGA
GTAGGAATGG AACAGCTGGC TTATTACCAC CAGGAATGGA CCGTCTTCAA TAGCTGGTGT
AGTCAGGGAG CTGATTGCAT CACCCCCGGC CTTTATGCAA TGGTTGGGGC TGCAGCCTGC
TTAGGTGGGG TGACTCGGAT GACTGTTTCT CTTGTTGTCA TAATGTTTGA ACTGACTGGT
GGCTTAGAAT ACATCGTGCC TCTGATGGCT GCAGCCATGA CAAGCAAGTG GGTGGCAGAT
GCTCTTGGGC GGGAGGGCAT CTATGATGCC CACATCCGTC TCAATGGATA CCCCTTTCTT
GAAGCCAAAG AAGAGTTTGC TCATAAGACC CTGGCAATGG ATGTGATGAA ACCCCGGAGA
AATGATCCTT TGTTGACTGT CCTTACTCAG GACAGTATGA CTGTGGAAGA TGTAGAGACC
ATAATCAGTG AAACCACTTA CAGTGGCTTC CCAGTGGTGG TATCCCGGGA GTCCCAAAGA
CTTGTGGGCT TTGTCCTCCG AAGAGATCTC ATTATTTCAA TTGAAAATGC TCGAAAGAAA
CAGGATGGGG TTGTTAGCAC TTCCATCATT TATTTCACGG AGCATTCTCC TCCATTGCCA
CCATACACTC CACCCACTCT AAAGCTTCGG AACATCCTCG ATCTCAGCCC CTTCACTGTG
ACTGACCTTA CACCCATGGA GATCGTAGTG GATATTTTCC GAAAGCTGGG ACTGCGGCAG
TGCCTGGTTA CACACAACGG GCGATTGCTT GGAATCATTA CCAAAAAGGA TGTGTTAAAG
CATATAGCAC AGATGGCGAA CCAAGATCCT GATTCCATTC TCTTCAACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21666
Clone ID Related Accession (Same CDS sequence) NM_001127898 , NM_001127899
Accession Version NM_001127898.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2451bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product H(+)/Cl(-) exchange transporter 5 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA652242.1, AK056560.1, AC231645.2, BC051691.1, AK025562.1 and AA743724.1. On Aug 21, 2013 this sequence version replaced gi:442535512. Transcript Variant: This variant (2, also known as type 1) uses an alternate splice site in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK056560.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGCCATGT GGCAGGGTGC CATGGATAAC AGAGGCTTTC AGCAGGGGAG TTTTAGTAGC 
TTCCAGAACA GCTCCAGTGA TGAAGACCTG ATGGACATTC CAGCAACCGC TATGGATTTC
TCCATGAGAG ATGATGTTCC TCCCTTAGAC CGAGAAGTAG GAGAGGACAA GTCGTACAAT
GGTGGAGGAA TAGGTTCTTC AAATAGGATC ATGGACTTCT TGGAGGAGCC AATCCCTGGT
GTAGGGACCT ATGATGATTT CAATACAATT GATTGGGTGA GAGAGAAGTC TCGAGACCGG
GATAGGCACC GAGAGATTAC CAATAAAAGC AAAGAGTCAA CATGGGCCTT AATTCACAGT
GTGAGTGATG CTTTTTCCGG CTGGTTGTTG ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG
TTAGCTGGTT TGATAGACAT CTCTGCTCAT TGGATGACAG ACTTAAAAGA AGGTATATGC
ACAGGGGGAT TCTGGTTTAA CCATGAACAT TGTTGCTGGA ACTCTGAGCA TGTCACCTTT
GAAGAGAGAG ACAAATGTCC AGAGTGGAAT AGTTGGTCCC AGCTTATCAT CAGCACAGAT
GAGGGAGCCT TTGCCTACAT AGTCAATTAT TTCATGTACG TCCTCTGGGC TCTCCTATTT
GCCTTCCTTG CCGTATCTCT TGTCAAGGTG TTTGCGCCTT ATGCCTGTGG CTCTGGAATC
CCTGAGATAA AAACTATCTT GAGTGGTTTC ATTATTAGGG GCTATTTGGG TAAGTGGACT
CTGGTTATCA AAACCATCAC CTTGGTGCTG GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA
GAGGGCCCTC TAGTGCACGT GGCTTGCTGC TGTGGGAACA TCCTGTGCCA CTGCTTCAAC
AAATACAGGA AGAATGAAGC CAAGCGCAGA GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT
GTATCTGTAG CCTTTGGAGC ACCTATAGGT GGAGTATTAT TCAGCCTTGA AGAGGTCAGC
TACTATTTTC CCCTCAAAAC ATTGTGGCGT TCATTCTTTG CTGCCTTGGT GGCAGCATTC
ACTCTACGCT CCATCAATCC ATTTGGGAAC AGCCGCCTGG TACTATTTTA TGTGGAGTTT
CACACCCCAT GGCATCTCTT TGAGCTCGTG CCATTCATTC TGCTGGGCAT ATTTGGTGGT
CTGTGGGGAG CACTGTTTAT CCGCACAAAC ATTGCCTGGT GTCGGAAGCG AAAGACCACC
CAGTTGGGCA AGTATCCTGT TATAGAGGTA CTCGTCGTGA CAGCCATCAC TGCCATCCTG
GCTTTCCCCA ATGAATACAC TCGGATGAGC ACAAGTGAGC TCATTTCTGA GCTGTTTAAT
GACTGTGGCC TTCTGGACTC CTCCAAGCTC TGTGATTATG AGAACCGTTT CAACACAAGC
AAAGGGGGTG AACTGCCTGA CAGACCGGCT GGCGTGGGAG TCTACAGTGC AATGTGGCAG
CTGGCTTTAA CACTCATACT GAAAATTGTC ATTACTATAT TCACCTTTGG CATGAAGATC
CCTTCTGGCC TCTTTATCCC TAGCATGGCT GTTGGTGCTA TAGCAGGTCG ACTTCTAGGA
GTAGGAATGG AACAGCTGGC TTATTACCAC CAGGAATGGA CCGTCTTCAA TAGCTGGTGT
AGTCAGGGAG CTGATTGCAT CACCCCCGGC CTTTATGCAA TGGTTGGGGC TGCAGCCTGC
TTAGGTGGGG TGACTCGGAT GACTGTTTCT CTTGTTGTCA TAATGTTTGA ACTGACTGGT
GGCTTAGAAT ACATCGTGCC TCTGATGGCT GCAGCCATGA CAAGCAAGTG GGTGGCAGAT
GCTCTTGGGC GGGAGGGCAT CTATGATGCC CACATCCGTC TCAATGGATA CCCCTTTCTT
GAAGCCAAAG AAGAGTTTGC TCATAAGACC CTGGCAATGG ATGTGATGAA ACCCCGGAGA
AATGATCCTT TGTTGACTGT CCTTACTCAG GACAGTATGA CTGTGGAAGA TGTAGAGACC
ATAATCAGTG AAACCACTTA CAGTGGCTTC CCAGTGGTGG TATCCCGGGA GTCCCAAAGA
CTTGTGGGCT TTGTCCTCCG AAGAGATCTC ATTATTTCAA TTGAAAATGC TCGAAAGAAA
CAGGATGGGG TTGTTAGCAC TTCCATCATT TATTTCACGG AGCATTCTCC TCCATTGCCA
CCATACACTC CACCCACTCT AAAGCTTCGG AACATCCTCG ATCTCAGCCC CTTCACTGTG
ACTGACCTTA CACCCATGGA GATCGTAGTG GATATTTTCC GAAAGCTGGG ACTGCGGCAG
TGCCTGGTTA CACACAACGG GCGATTGCTT GGAATCATTA CCAAAAAGGA TGTGTTAAAG
CATATAGCAC AGATGGCGAA CCAAGATCCT GATTCCATTC TCTTCAACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001121370.1
CDS383..2833
Misc Feature(1)326..328(+)
Misc Feature(2)806..2302(+)
Misc Feature(3)1091..2266(+)
Misc Feature(4)1223..1225(+)
Misc Feature(5)1394..1396(+)
Misc Feature(6)2339..2779(+)
Misc Feature(7)2375..2785(+)
Exon (1)1..178
Gene:CLCN5
Gene Synonym:
Exon (2)179..254
Gene:CLCN5
Gene Synonym:
Exon (3)255..398
Gene:CLCN5
Gene Synonym:
Exon (4)399..545
Gene:CLCN5
Gene Synonym:
Exon (5)546..697
Gene:CLCN5
Gene Synonym:
Exon (6)698..797
Gene:CLCN5
Gene Synonym:
Exon (7)798..985
Gene:CLCN5
Gene Synonym:
Exon (8)986..1108
Gene:CLCN5
Gene Synonym:
Exon (9)1109..1315
Gene:CLCN5
Gene Synonym:
Exon (10)1316..1396
Gene:CLCN5
Gene Synonym:
Exon (11)1397..1939
Gene:CLCN5
Gene Synonym:
Exon (12)1940..2126
Gene:CLCN5
Gene Synonym:
Exon (13)2127..2525
Gene:CLCN5
Gene Synonym:
Exon (14)2526..2742
Gene:CLCN5
Gene Synonym:
Exon (15)2743..9849
Gene:CLCN5
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001127898
Organism Homo sapiens (human)
Definition Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127898

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGCCATGT GGCAGGGTGC CATGGATAAC AGAGGCTTTC AGCAGGGGAG TTTTAGTAGC 
TTCCAGAACA GCTCCAGTGA TGAAGACCTG ATGGACATTC CAGCAACCGC TATGGATTTC
TCCATGAGAG ATGATGTTCC TCCCTTAGAC CGAGAAGTAG GAGAGGACAA GTCGTACAAT
GGTGGAGGAA TAGGTTCTTC AAATAGGATC ATGGACTTCT TGGAGGAGCC AATCCCTGGT
GTAGGGACCT ATGATGATTT CAATACAATT GATTGGGTGA GAGAGAAGTC TCGAGACCGG
GATAGGCACC GAGAGATTAC CAATAAAAGC AAAGAGTCAA CATGGGCCTT AATTCACAGT
GTGAGTGATG CTTTTTCCGG CTGGTTGTTG ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG
TTAGCTGGTT TGATAGACAT CTCTGCTCAT TGGATGACAG ACTTAAAAGA AGGTATATGC
ACAGGGGGAT TCTGGTTTAA CCATGAACAT TGTTGCTGGA ACTCTGAGCA TGTCACCTTT
GAAGAGAGAG ACAAATGTCC AGAGTGGAAT AGTTGGTCCC AGCTTATCAT CAGCACAGAT
GAGGGAGCCT TTGCCTACAT AGTCAATTAT TTCATGTACG TCCTCTGGGC TCTCCTATTT
GCCTTCCTTG CCGTATCTCT TGTCAAGGTG TTTGCGCCTT ATGCCTGTGG CTCTGGAATC
CCTGAGATAA AAACTATCTT GAGTGGTTTC ATTATTAGGG GCTATTTGGG TAAGTGGACT
CTGGTTATCA AAACCATCAC CTTGGTGCTG GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA
GAGGGCCCTC TAGTGCACGT GGCTTGCTGC TGTGGGAACA TCCTGTGCCA CTGCTTCAAC
AAATACAGGA AGAATGAAGC CAAGCGCAGA GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT
GTATCTGTAG CCTTTGGAGC ACCTATAGGT GGAGTATTAT TCAGCCTTGA AGAGGTCAGC
TACTATTTTC CCCTCAAAAC ATTGTGGCGT TCATTCTTTG CTGCCTTGGT GGCAGCATTC
ACTCTACGCT CCATCAATCC ATTTGGGAAC AGCCGCCTGG TACTATTTTA TGTGGAGTTT
CACACCCCAT GGCATCTCTT TGAGCTCGTG CCATTCATTC TGCTGGGCAT ATTTGGTGGT
CTGTGGGGAG CACTGTTTAT CCGCACAAAC ATTGCCTGGT GTCGGAAGCG AAAGACCACC
CAGTTGGGCA AGTATCCTGT TATAGAGGTA CTCGTCGTGA CAGCCATCAC TGCCATCCTG
GCTTTCCCCA ATGAATACAC TCGGATGAGC ACAAGTGAGC TCATTTCTGA GCTGTTTAAT
GACTGTGGCC TTCTGGACTC CTCCAAGCTC TGTGATTATG AGAACCGTTT CAACACAAGC
AAAGGGGGTG AACTGCCTGA CAGACCGGCT GGCGTGGGAG TCTACAGTGC AATGTGGCAG
CTGGCTTTAA CACTCATACT GAAAATTGTC ATTACTATAT TCACCTTTGG CATGAAGATC
CCTTCTGGCC TCTTTATCCC TAGCATGGCT GTTGGTGCTA TAGCAGGTCG ACTTCTAGGA
GTAGGAATGG AACAGCTGGC TTATTACCAC CAGGAATGGA CCGTCTTCAA TAGCTGGTGT
AGTCAGGGAG CTGATTGCAT CACCCCCGGC CTTTATGCAA TGGTTGGGGC TGCAGCCTGC
TTAGGTGGGG TGACTCGGAT GACTGTTTCT CTTGTTGTCA TAATGTTTGA ACTGACTGGT
GGCTTAGAAT ACATCGTGCC TCTGATGGCT GCAGCCATGA CAAGCAAGTG GGTGGCAGAT
GCTCTTGGGC GGGAGGGCAT CTATGATGCC CACATCCGTC TCAATGGATA CCCCTTTCTT
GAAGCCAAAG AAGAGTTTGC TCATAAGACC CTGGCAATGG ATGTGATGAA ACCCCGGAGA
AATGATCCTT TGTTGACTGT CCTTACTCAG GACAGTATGA CTGTGGAAGA TGTAGAGACC
ATAATCAGTG AAACCACTTA CAGTGGCTTC CCAGTGGTGG TATCCCGGGA GTCCCAAAGA
CTTGTGGGCT TTGTCCTCCG AAGAGATCTC ATTATTTCAA TTGAAAATGC TCGAAAGAAA
CAGGATGGGG TTGTTAGCAC TTCCATCATT TATTTCACGG AGCATTCTCC TCCATTGCCA
CCATACACTC CACCCACTCT AAAGCTTCGG AACATCCTCG ATCTCAGCCC CTTCACTGTG
ACTGACCTTA CACCCATGGA GATCGTAGTG GATATTTTCC GAAAGCTGGG ACTGCGGCAG
TGCCTGGTTA CACACAACGG GCGATTGCTT GGAATCATTA CCAAAAAGGA TGTGTTAAAG
CATATAGCAC AGATGGCGAA CCAAGATCCT GATTCCATTC TCTTCAACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21358
Clone ID Related Accession (Same CDS sequence) NM_000084
Accession Version NM_000084.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2241bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product H(+)/Cl(-) exchange transporter 5 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX950885.1, AK290940.1, AC231645.2, BC051691.1, AK025562.1 and AA743724.1. On Aug 21, 2013 this sequence version replaced gi:441703659. Transcript Variant: This variant (3, also known as type 3) lacks several 5' exons but has an alternate 5' exon, and it thus differs in the 5' UTR and uses a downstream start codon, compared to variant 1. The resulting isoform (b) has a shorter N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK308089.1, AK290940.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGACTTCT TGGAGGAGCC AATCCCTGGT GTAGGGACCT ATGATGATTT CAATACAATT 
GATTGGGTGA GAGAGAAGTC TCGAGACCGG GATAGGCACC GAGAGATTAC CAATAAAAGC
AAAGAGTCAA CATGGGCCTT AATTCACAGT GTGAGTGATG CTTTTTCCGG CTGGTTGTTG
ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG TTAGCTGGTT TGATAGACAT CTCTGCTCAT
TGGATGACAG ACTTAAAAGA AGGTATATGC ACAGGGGGAT TCTGGTTTAA CCATGAACAT
TGTTGCTGGA ACTCTGAGCA TGTCACCTTT GAAGAGAGAG ACAAATGTCC AGAGTGGAAT
AGTTGGTCCC AGCTTATCAT CAGCACAGAT GAGGGAGCCT TTGCCTACAT AGTCAATTAT
TTCATGTACG TCCTCTGGGC TCTCCTATTT GCCTTCCTTG CCGTATCTCT TGTCAAGGTG
TTTGCGCCTT ATGCCTGTGG CTCTGGAATC CCTGAGATAA AAACTATCTT GAGTGGTTTC
ATTATTAGGG GCTATTTGGG TAAGTGGACT CTGGTTATCA AAACCATCAC CTTGGTGCTG
GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA GAGGGCCCTC TAGTGCACGT GGCTTGCTGC
TGTGGGAACA TCCTGTGCCA CTGCTTCAAC AAATACAGGA AGAATGAAGC CAAGCGCAGA
GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT GTATCTGTAG CCTTTGGAGC ACCTATAGGT
GGAGTATTAT TCAGCCTTGA AGAGGTCAGC TACTATTTTC CCCTCAAAAC ATTGTGGCGT
TCATTCTTTG CTGCCTTGGT GGCAGCATTC ACTCTACGCT CCATCAATCC ATTTGGGAAC
AGCCGCCTGG TACTATTTTA TGTGGAGTTT CACACCCCAT GGCATCTCTT TGAGCTCGTG
CCATTCATTC TGCTGGGCAT ATTTGGTGGT CTGTGGGGAG CACTGTTTAT CCGCACAAAC
ATTGCCTGGT GTCGGAAGCG AAAGACCACC CAGTTGGGCA AGTATCCTGT TATAGAGGTA
CTCGTCGTGA CAGCCATCAC TGCCATCCTG GCTTTCCCCA ATGAATACAC TCGGATGAGC
ACAAGTGAGC TCATTTCTGA GCTGTTTAAT GACTGTGGCC TTCTGGACTC CTCCAAGCTC
TGTGATTATG AGAACCGTTT CAACACAAGC AAAGGGGGTG AACTGCCTGA CAGACCGGCT
GGCGTGGGAG TCTACAGTGC AATGTGGCAG CTGGCTTTAA CACTCATACT GAAAATTGTC
ATTACTATAT TCACCTTTGG CATGAAGATC CCTTCTGGCC TCTTTATCCC TAGCATGGCT
GTTGGTGCTA TAGCAGGTCG ACTTCTAGGA GTAGGAATGG AACAGCTGGC TTATTACCAC
CAGGAATGGA CCGTCTTCAA TAGCTGGTGT AGTCAGGGAG CTGATTGCAT CACCCCCGGC
CTTTATGCAA TGGTTGGGGC TGCAGCCTGC TTAGGTGGGG TGACTCGGAT GACTGTTTCT
CTTGTTGTCA TAATGTTTGA ACTGACTGGT GGCTTAGAAT ACATCGTGCC TCTGATGGCT
GCAGCCATGA CAAGCAAGTG GGTGGCAGAT GCTCTTGGGC GGGAGGGCAT CTATGATGCC
CACATCCGTC TCAATGGATA CCCCTTTCTT GAAGCCAAAG AAGAGTTTGC TCATAAGACC
CTGGCAATGG ATGTGATGAA ACCCCGGAGA AATGATCCTT TGTTGACTGT CCTTACTCAG
GACAGTATGA CTGTGGAAGA TGTAGAGACC ATAATCAGTG AAACCACTTA CAGTGGCTTC
CCAGTGGTGG TATCCCGGGA GTCCCAAAGA CTTGTGGGCT TTGTCCTCCG AAGAGATCTC
ATTATTTCAA TTGAAAATGC TCGAAAGAAA CAGGATGGGG TTGTTAGCAC TTCCATCATT
TATTTCACGG AGCATTCTCC TCCATTGCCA CCATACACTC CACCCACTCT AAAGCTTCGG
AACATCCTCG ATCTCAGCCC CTTCACTGTG ACTGACCTTA CACCCATGGA GATCGTAGTG
GATATTTTCC GAAAGCTGGG ACTGCGGCAG TGCCTGGTTA CACACAACGG GCGATTGCTT
GGAATCATTA CCAAAAAGGA TGTGTTAAAG CATATAGCAC AGATGGCGAA CCAAGATCCT
GATTCCATTC TCTTCAACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000075.1
CDS249..2489
Misc Feature(1)135..137(+)
Misc Feature(2)411..524(+)
Misc Feature(3)462..1958(+)
Misc Feature(4)660..731(+)
Misc Feature(5)747..1922(+)
Misc Feature(6)747..761(+)
Misc Feature(7)804..863(+)
Misc Feature(8)873..887(+)
Misc Feature(9)879..938(+)
Misc Feature(10)879..881(+)
Misc Feature(11)879..881(+)
Misc Feature(12)1050..1052(+)
Misc Feature(13)1050..1052(+)
Misc Feature(14)1080..1136(+)
Misc Feature(15)1203..1283(+)
Misc Feature(16)1302..1364(+)
Misc Feature(17)1530..1592(+)
Misc Feature(18)1605..1664(+)
Misc Feature(19)1605..1619(+)
Misc Feature(20)1851..1904(+)
Misc Feature(21)1995..2435(+)
Misc Feature(22)2031..2441(+)
Exon (1)1..201
Gene:CLCN5
Gene Synonym:
Exon (2)202..353
Gene:CLCN5
Gene Synonym:
Exon (3)354..453
Gene:CLCN5
Gene Synonym:
Exon (4)454..641
Gene:CLCN5
Gene Synonym:
Exon (5)642..764
Gene:CLCN5
Gene Synonym:
Exon (6)765..971
Gene:CLCN5
Gene Synonym:
Exon (7)972..1052
Gene:CLCN5
Gene Synonym:
Exon (8)1053..1595
Gene:CLCN5
Gene Synonym:
Exon (9)1596..1782
Gene:CLCN5
Gene Synonym:
Exon (10)1783..2181
Gene:CLCN5
Gene Synonym:
Exon (11)2182..2398
Gene:CLCN5
Gene Synonym:
Exon (12)2399..9505
Gene:CLCN5
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000084
Organism Homo sapiens (human)
Definition Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000084

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGACTTCT TGGAGGAGCC AATCCCTGGT GTAGGGACCT ATGATGATTT CAATACAATT 
GATTGGGTGA GAGAGAAGTC TCGAGACCGG GATAGGCACC GAGAGATTAC CAATAAAAGC
AAAGAGTCAA CATGGGCCTT AATTCACAGT GTGAGTGATG CTTTTTCCGG CTGGTTGTTG
ATGCTCCTTA TTGGGCTTTT ATCAGGTTCG TTAGCTGGTT TGATAGACAT CTCTGCTCAT
TGGATGACAG ACTTAAAAGA AGGTATATGC ACAGGGGGAT TCTGGTTTAA CCATGAACAT
TGTTGCTGGA ACTCTGAGCA TGTCACCTTT GAAGAGAGAG ACAAATGTCC AGAGTGGAAT
AGTTGGTCCC AGCTTATCAT CAGCACAGAT GAGGGAGCCT TTGCCTACAT AGTCAATTAT
TTCATGTACG TCCTCTGGGC TCTCCTATTT GCCTTCCTTG CCGTATCTCT TGTCAAGGTG
TTTGCGCCTT ATGCCTGTGG CTCTGGAATC CCTGAGATAA AAACTATCTT GAGTGGTTTC
ATTATTAGGG GCTATTTGGG TAAGTGGACT CTGGTTATCA AAACCATCAC CTTGGTGCTG
GCAGTGTCAT CTGGCTTGAG CCTGGGCAAA GAGGGCCCTC TAGTGCACGT GGCTTGCTGC
TGTGGGAACA TCCTGTGCCA CTGCTTCAAC AAATACAGGA AGAATGAAGC CAAGCGCAGA
GAGGTCTTGT CGGCTGCAGC AGCAGCTGGT GTATCTGTAG CCTTTGGAGC ACCTATAGGT
GGAGTATTAT TCAGCCTTGA AGAGGTCAGC TACTATTTTC CCCTCAAAAC ATTGTGGCGT
TCATTCTTTG CTGCCTTGGT GGCAGCATTC ACTCTACGCT CCATCAATCC ATTTGGGAAC
AGCCGCCTGG TACTATTTTA TGTGGAGTTT CACACCCCAT GGCATCTCTT TGAGCTCGTG
CCATTCATTC TGCTGGGCAT ATTTGGTGGT CTGTGGGGAG CACTGTTTAT CCGCACAAAC
ATTGCCTGGT GTCGGAAGCG AAAGACCACC CAGTTGGGCA AGTATCCTGT TATAGAGGTA
CTCGTCGTGA CAGCCATCAC TGCCATCCTG GCTTTCCCCA ATGAATACAC TCGGATGAGC
ACAAGTGAGC TCATTTCTGA GCTGTTTAAT GACTGTGGCC TTCTGGACTC CTCCAAGCTC
TGTGATTATG AGAACCGTTT CAACACAAGC AAAGGGGGTG AACTGCCTGA CAGACCGGCT
GGCGTGGGAG TCTACAGTGC AATGTGGCAG CTGGCTTTAA CACTCATACT GAAAATTGTC
ATTACTATAT TCACCTTTGG CATGAAGATC CCTTCTGGCC TCTTTATCCC TAGCATGGCT
GTTGGTGCTA TAGCAGGTCG ACTTCTAGGA GTAGGAATGG AACAGCTGGC TTATTACCAC
CAGGAATGGA CCGTCTTCAA TAGCTGGTGT AGTCAGGGAG CTGATTGCAT CACCCCCGGC
CTTTATGCAA TGGTTGGGGC TGCAGCCTGC TTAGGTGGGG TGACTCGGAT GACTGTTTCT
CTTGTTGTCA TAATGTTTGA ACTGACTGGT GGCTTAGAAT ACATCGTGCC TCTGATGGCT
GCAGCCATGA CAAGCAAGTG GGTGGCAGAT GCTCTTGGGC GGGAGGGCAT CTATGATGCC
CACATCCGTC TCAATGGATA CCCCTTTCTT GAAGCCAAAG AAGAGTTTGC TCATAAGACC
CTGGCAATGG ATGTGATGAA ACCCCGGAGA AATGATCCTT TGTTGACTGT CCTTACTCAG
GACAGTATGA CTGTGGAAGA TGTAGAGACC ATAATCAGTG AAACCACTTA CAGTGGCTTC
CCAGTGGTGG TATCCCGGGA GTCCCAAAGA CTTGTGGGCT TTGTCCTCCG AAGAGATCTC
ATTATTTCAA TTGAAAATGC TCGAAAGAAA CAGGATGGGG TTGTTAGCAC TTCCATCATT
TATTTCACGG AGCATTCTCC TCCATTGCCA CCATACACTC CACCCACTCT AAAGCTTCGG
AACATCCTCG ATCTCAGCCC CTTCACTGTG ACTGACCTTA CACCCATGGA GATCGTAGTG
GATATTTTCC GAAAGCTGGG ACTGCGGCAG TGCCTGGTTA CACACAACGG GCGATTGCTT
GGAATCATTA CCAAAAAGGA TGTGTTAAAG CATATAGCAC AGATGGCGAA CCAAGATCCT
GATTCCATTC TCTTCAACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16814
Clone ID Related Accession (Same CDS sequence) NM_001272102
Accession Version NM_001272102.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 195bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product H(+)/Cl(-) exchange transporter 5 isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK092049.1 and BF513571.1. Transcript Variant: This variant (5) uses an alternate splice site in the 5' UTR, it lacks several 3' exons but has an alternate 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) has a distinct and shorter C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DB014315.1, DA879207.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
ATGGCCATGT GGCAGGGTGC CATGGATAAC AGAGGCTTTC AGCAGGGGAG TTTTAGTAGC 
TTCCAGAACA GCTCCAGTGA TGAAGACCTG ATGGACATTC CAGCAACCGC TATGGATTTC
TCCATGAGAG ATGATGTTCC TCCCTTAGAC CGAGAAGTAG GAGGTATCAT TATTGGTGAT
GATAATTTAT CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001259031.1
CDS383..577
Misc Feature(1)326..328(+)
Exon (1)1..178
Gene:CLCN5
Gene Synonym:
Exon (2)179..254
Gene:CLCN5
Gene Synonym:
Exon (3)255..398
Gene:CLCN5
Gene Synonym:
Exon (4)399..624
Gene:CLCN5
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001272102
Organism Homo sapiens (human)
Definition Homo sapiens chloride channel, voltage-sensitive 5 (CLCN5), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001272102

ORF Insert Sequence:

1
61
121
181
ATGGCCATGT GGCAGGGTGC CATGGATAAC AGAGGCTTTC AGCAGGGGAG TTTTAGTAGC 
TTCCAGAACA GCTCCAGTGA TGAAGACCTG ATGGACATTC CAGCAACCGC TATGGATTTC
TCCATGAGAG ATGATGTTCC TCCCTTAGAC CGAGAAGTAG GAGGTATCAT TATTGGTGAT
GATAATTTAT CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Conformational defects underlie proteasomal degradation of Dent's disease-causing mutants of ClC-5
Biochem. J. 452 (3), 391-400 (2013)
D'Antonio C, Molinski S, Ahmadi S, Huan LJ, Wellhauser L and Bear CE.


book

Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients
Proc. Natl. Acad. Sci. U.S.A. 110 (17), 7014-7019 (2013)
Gorvin CM, Wilmer MJ, Piret SE, Harding B, van den Heuvel LP, Wrong O, Jat PS, Lippiat JD, Levtchenko EN and Thakker RV.


book

The CLC-5 2Cl(-)/H(+) exchange transporter in endosomal function and Dent's disease
Front Physiol 3, 449 (2012)
Lippiat JD and Smith AJ.


book

Four additional CLCN5 exons encode a widely expressed novel long CLC-5 isoform but fail to explain Dent's phenotype in patients without mutations in the short variant
Kidney Blood Press. Res. 26 (3), 176-184 (2003)
Ludwig M, Waldegger S, Nuutinen M, Bokenkamp A, Reissinger A, Steckelbroeck S and Utsch B.


book

Cloning and characterization of CLCN5, the human kidney chloride channel gene implicated in Dent disease (an X-linked hereditary nephrolithiasis)
Genomics 29 (3), 598-606 (1995)
Fisher SE, van Bakel I, Lloyd SE, Pearce SH, Thakker RV and Craig IW.


book

Hypercalciuria and nephrocalcinosis in patients with idiopathic low-molecular-weight proteinuria in Japan: is the disease identical to Dent's disease in United Kingdom?
Nephron 69 (3), 242-247 (1995)
Igarashi T, Hayakawa H, Shiraga H, Kawato H, Yan K, Kawaguchi H, Yamanaka T, Tsuchida S and Akagi K.


book

Isolation and partial characterization of a chloride channel gene which is expressed in kidney and is a candidate for Dent's disease (an X-linked hereditary nephrolithiasis)
Hum. Mol. Genet. 3 (11), 2053-2059 (1994)
Fisher SE, Black GC, Lloyd SE, Hatchwell E, Wrong O, Thakker RV and Craig IW.


book

Dent's disease, a renal Fanconi syndrome with nephrocalcinosis and kidney stones, is associated with a microdeletion involving DXS255 and maps to Xp11.22
Hum. Mol. Genet. 2 (12), 2129-2134 (1993)
Pook MA, Wrong O, Wooding C, Norden AG, Feest TG and Thakker RV.


book

Mapping the gene causing X-linked recessive nephrolithiasis to Xp11.22 by linkage studies
J. Clin. Invest. 91 (6), 2351-2357 (1993)
Scheinman SJ, Pook MA, Wooding C, Pang JT, Frymoyer PA and Thakker RV.


book

Dent Disease
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Lieske,J.C., Milliner,D.S., Beara-Lasic,L. and Rossetti,S.


 
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