The following CALR3 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CALR3 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||Documents for ORF clone product in dufault vector
||ORF Nucleotide Sequence (Length: 1155bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC014595.2, DB459545.1,
AB576176.1, BP370084.1, AA910019.1 and AA724299.1.
This sequence is a reference standard in the RefSeqGene project.
On Dec 20, 2011 this sequence version replaced gi:187608347.
Summary: The protein encoded by this gene belongs to the
calreticulin family, members of which are calcium-binding
chaperones localized mainly in the endoplasmic reticulum. This
protein is also localized to the endoplasmic reticulum lumen,
however, its capacity for calcium-binding may be absent or much
lower than other family members. This gene is specifically
expressed in the testis, and may be required for sperm fertility.
Mutation in this gene has been associated with familial
hypertrophic cardiomyopathy. [provided by RefSeq, Dec 2011].
Transcript exon combination :: BC014595.2, AK058084.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.