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CALR3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol CALR3
Entrez Gene ID 125972
Full Name calreticulin 3
Synonyms CMH19, CRT2, CT93
General protein information
Preferred Names
calreticulin-3
Names
calreticulin-3
calsperin
calreticulin-2
cancer/testis antigen 93
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.11

Summary The protein encoded by this gene belongs to the calreticulin family, members of which are calcium-binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy. [provided by RefSeq, Dec 2011]. lac of sum
Disorder MIM:

611414

Disorder Html:





The following CALR3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CALR3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19764 NM_145046 Homo sapiens calreticulin 3 (CALR3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu19764
Accession Version NM_145046.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1155bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product calreticulin-3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC014595.2, DB459545.1, AB576176.1, BP370084.1, AA910019.1 and AA724299.1. This sequence is a reference standard in the RefSeqGene project. On Dec 20, 2011 this sequence version replaced gi:187608347. Summary: The protein encoded by this gene belongs to the calreticulin family, members of which are calcium-binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy. [provided by RefSeq, Dec 2011]. ##Evidence-Data-START## Transcript exon combination :: BC014595.2, AK058084.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGCCCGGG CTTTGGTCCA GCTCTGGGCC ATATGCATGC TGCGAGTGGC GCTGGCTACC 
GTCTATTTCC AAGAGGAATT TCTAGACGGA GAGCATTGGA GAAACCGATG GTTGCAGTCC
ACCAATGACT CCCGATTTGG GCATTTTAGA CTTTCGTCGG GCAAGTTTTA TGGTCATAAA
GAGAAAGATA AAGGTCTGCA AACCACTCAG AATGGCCGAT TCTATGCCAT CTCTGCACGC
TTCAAACCGT TCAGCAATAA AGGGAAAACT CTGGTTATTC AGTACACAGT AAAACATGAG
CAGAAGATGG ACTGTGGAGG GGGCTACATT AAGGTCTTTC CTGCAGACAT TGACCAGAAG
AACCTGAATG GAAAATCGCA GTACTATATT ATGTTTGGAC CCGATATTTG TGGATTTGAT
ATCAAGAAAG TTCATGTTAT TTTACATTTC AAGAATAAGT ATCACGAAAA CAAGAAACTG
ATCAGGTGTA AGGTTGATGG CTTCACACAC CTGTACACTC TAATTTTAAG ACCAGATCTT
TCTTATGATG TGAAAATTGA TGGTCAGTCA ATTGAATCCG GCAGCATAGA GTACGACTGG
AACTTAACAT CACTCAAGAA GGAAACGTCC CCGGCAGAAT CGAAGGATTG GGAACAGACT
AAAGACAACA AAGCCCAGGA CTGGGAGAAG CATTTTCTGG ACGCCAGCAC CAGCAAGCAG
AGCGACTGGA ACGGTGACCT GGATGGGGAC TGGCCAGCGC CGATGCTCCA GAAGCCCCCG
TACCAGGATG GCCTGAAACC AGAAGGTATT CATAAAGACG TCTGGCTCCA CCGTAAGATG
AAGAATACCG ACTATTTGAC GCAGTATGAC CTCTCAGAAT TTGAGAACAT TGGTGCCATT
GGCCTGGAGC TTTGGCAGGT GAGATCTGGA ACCATTTTTG ATAACTTTCT GATCACAGAT
GATGAAGAGT ACGCAGATAA TTTTGGCAAG GCCACCTGGG GCGAAACCAA GGGTCCAGAA
AGGGAGATGG ATGCCATACA GGCCAAGGAG GAAATGAAGA AGGCCCGCGA GGAAGAGGAG
GAAGAGCTGC TGTCGGGAAA AATTAACAGG CACGAACATT ACTTCAATCA ATTTCACAGA
AGGAATGAAC TTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_659483.2
CDS64..1218
Misc Feature(1)25..27(+)
Misc Feature(2)121..654(+)
Misc Feature(3)124..1017(+)
Misc Feature(4)634..798(+)
Misc Feature(5)655..945(+)
Misc Feature(6)808..912(+)
Misc Feature(7)946..1215(+)
Misc Feature(8)1204..1215(+)
Exon (1)1..154
Gene:CALR3
Gene Synonym:
Exon (2)155..256
Gene:CALR3
Gene Synonym:
Exon (3)257..460
Gene:CALR3
Gene Synonym:
Exon (4)461..555
Gene:CALR3
Gene Synonym:
Exon (5)556..741
Gene:CALR3
Gene Synonym:
Exon (6)742..849
Gene:CALR3
Gene Synonym:
Exon (7)850..981
Gene:CALR3
Gene Synonym:
Exon (8)982..1074
Gene:CALR3
Gene Synonym:
Exon (9)1075..1292
Gene:CALR3
Gene Synonym:
Translation
Position Chain Variation Link
21 21 a, g dbSNP:752683986
28 28 c, g dbSNP:764073211
30 30 c, g dbSNP:199995239
31 31 -, g dbSNP:762834315
35 35 c, g dbSNP:753534940
51 51 a, c dbSNP:766172306
53 53 g, t dbSNP:371362207
60 60 a, c dbSNP:774525923
61 61 c, g dbSNP:559213492
62 62 c, g, t dbSNP:776126382
63 63 -, c dbSNP:775426463
63 63 a, c, t dbSNP:745990968
64 64 a, g dbSNP:776813962
66 66 g, t dbSNP:771093368
79 79 a, g dbSNP:747264355
81 81 c, t dbSNP:777364731
83 83 a, c dbSNP:538611499
84 84 c, g dbSNP:201886703
85 85 c, t dbSNP:11544148
89 89 g, t dbSNP:754504178
91 91 a, g dbSNP:3810201
92 92 c, t dbSNP:766005088
93 93 c, t dbSNP:762852375
94 94 a, g dbSNP:755784741
97 97 c, g, t dbSNP:764357332
118 118 g, t dbSNP:763443484
123 123 a, c, g, t dbSNP:370721650
124 124 a, g dbSNP:776652603
130 130 a, t dbSNP:368506422
145 145 c, g dbSNP:747141034
150 150 c, t dbSNP:773541894
159 159 c, t dbSNP:144355944
173 173 a, g dbSNP:749228587
176 176 g, t dbSNP:780211279
188 188 a, g dbSNP:149634686
190 190 a, g dbSNP:745435624
200 200 c, t dbSNP:780590548
205 205 c, t dbSNP:556663033
215 215 g, t dbSNP:751176255
219 219 a, g dbSNP:779192527
222 222 a, g dbSNP:372912264
224 224 a, g dbSNP:147300344
226 226 a, g dbSNP:766911825
229 229 c, t dbSNP:201808529
232 232 c, t dbSNP:368523051
233 233 a, g dbSNP:138350128
252 252 g, t dbSNP:201304731
257 257 a, g dbSNP:764572647
262 262 c, t dbSNP:775385558
263 263 a, g dbSNP:150907410
275 275 a, g dbSNP:369859530
278 278 a, g dbSNP:182376945
279 279 a, c, t dbSNP:577809057
280 280 c, g, t dbSNP:199561391
281 281 a, g dbSNP:372657559
282 282 a, g dbSNP:747826402
287 287 a, g dbSNP:780394746
294 294 -, c dbSNP:770476504
301 301 c, t dbSNP:756445681
302 302 a, g dbSNP:746369368
306 306 c, t dbSNP:201321577
308 308 a, g dbSNP:142951029
310 310 c, g dbSNP:751645170
311 311 c, t dbSNP:764305082
312 312 a, g dbSNP:570064234
331 331 a, c dbSNP:200449193
334 334 c, t dbSNP:765069343
336 336 c, g dbSNP:759314483
337 337 c, g dbSNP:776598394
351 351 -, a dbSNP:746722802
361 361 a, g dbSNP:766276146
371 371 g, t dbSNP:760627206
372 372 a, g dbSNP:772666036
375 375 a, c dbSNP:771571508
377 377 a, g dbSNP:747738664
381 381 a, c dbSNP:773929973
382 382 g, t dbSNP:770166604
386 386 c, g dbSNP:139061471
389 389 a, g dbSNP:781640024
398 398 c, t dbSNP:757803093
399 399 c, g dbSNP:185241971
426 426 c, g dbSNP:777941952
430 430 a, g dbSNP:758610313
440 440 c, t dbSNP:752960232
441 441 a, g dbSNP:374869347
444 444 a, g dbSNP:3810198
451 451 a, g dbSNP:753527738
460 460 g, t dbSNP:766228047
465 465 c, g dbSNP:750997835
466 466 a, g dbSNP:143932873
481 481 g, t dbSNP:762455628
485 485 c, t dbSNP:775271709
501 501 a, t dbSNP:771419918
513 513 c, t dbSNP:148241645
518 518 a, c dbSNP:761162376
528 528 c, g, t dbSNP:772657021
546 546 a, c dbSNP:143158265
551 551 a, g dbSNP:778791995
556 556 g, t dbSNP:780912191
563 563 a, g, t dbSNP:746917889
571 571 a, c, t dbSNP:376733366
574 574 c, t dbSNP:752204583
579 579 a, c dbSNP:552364605
580 580 a, g dbSNP:374187284
583 583 a, c dbSNP:143671909
609 609 c, t dbSNP:369476772
624 624 c, t dbSNP:762301226
627 627 -, t dbSNP:747656642
630 630 -, gtca dbSNP:778627769
642 642 c, t dbSNP:149108772
643 643 a, g dbSNP:764707663
657 657 c, t dbSNP:145046810
664 664 a, c dbSNP:775484097
667 667 c, t dbSNP:769879360
671 671 c, t dbSNP:150376706
672 672 a, t dbSNP:776906320
682 682 a, g dbSNP:111870908
689 689 c, t dbSNP:746871999
690 690 a, g dbSNP:777454147
695 695 c, t dbSNP:772004043
696 696 a, g dbSNP:748099861
702 702 a, g dbSNP:377026384
704 704 c, g, t dbSNP:550089146
705 705 a, g dbSNP:200669493
709 709 a, g dbSNP:529644089
711 711 c, t dbSNP:372889302
720 720 a, g dbSNP:764373762
721 721 a, g dbSNP:763397517
730 730 a, g dbSNP:368652672
736 736 g, t dbSNP:765297065
741 741 a, g, t dbSNP:776696174
765 765 c, t dbSNP:10403020
786 786 a, c, t dbSNP:753171373
787 787 a, g dbSNP:146669521
795 795 c, t dbSNP:201198066
796 796 a, g dbSNP:753917463
801 801 c, t dbSNP:780488544
805 805 a, g dbSNP:766372296
806 806 a, c, g dbSNP:10411092
808 808 a, g dbSNP:267605330
813 813 c, t dbSNP:149008417
817 817 c, t dbSNP:773363847
821 821 c, t dbSNP:771984164
824 824 c, t dbSNP:761736548
833 833 a, c dbSNP:774405654
834 834 a, g dbSNP:768662294
840 840 c, t dbSNP:143252466
843 843 a, g dbSNP:775009764
847 847 c, t dbSNP:267605329
849 849 g, t dbSNP:769250010
850 850 c, g dbSNP:200056222
851 851 a, g dbSNP:779188602
852 852 a, t dbSNP:755353074
853 853 a, g, t dbSNP:780461586
854 854 g, t dbSNP:756195821
863 863 c, t dbSNP:750420703
867 867 a, t dbSNP:767734348
876 876 c, t dbSNP:531275904
882 882 c, t dbSNP:371638034
883 883 a, g dbSNP:12459238
888 888 g, t dbSNP:183119380
895 895 c, t dbSNP:543953490
901 901 a, t dbSNP:752661774
911 911 c, t dbSNP:75099211
912 912 c, t dbSNP:142902333
913 913 a, g dbSNP:10404156
919 919 c, t dbSNP:770439289
922 922 a, t dbSNP:760304266
923 923 c, t dbSNP:772912504
924 924 a, c, g dbSNP:118131979
926 926 a, c, g dbSNP:201922129
937 937 c, t dbSNP:770159581
940 940 a, g dbSNP:753958854
946 946 a, g dbSNP:746379101
964 964 c, g dbSNP:374467745
966 966 c, t dbSNP:781409571
972 972 g, t dbSNP:757479953
986 986 g, t dbSNP:369518093
991 991 a, g dbSNP:753445939
1003 1003 g, t dbSNP:771113248
1024 1024 a, g dbSNP:143334090
1029 1029 a, g dbSNP:777944225
1032 1032 c, g dbSNP:758485228
1035 1035 a, c, t dbSNP:9305079
1039 1039 c, g dbSNP:147253682
1040 1040 a, g dbSNP:754830521
1050 1050 c, g dbSNP:753739592
1055 1055 c, t dbSNP:766349117
1065 1065 a, c, t dbSNP:143913852
1066 1066 a, g dbSNP:199535524
1070 1070 a, c dbSNP:761312779
1074 1074 a, g dbSNP:774121735
1091 1091 c, t dbSNP:748304873
1092 1092 a, g dbSNP:371168255
1099 1099 a, g dbSNP:768826027
1102 1102 c, t dbSNP:749516012
1122 1122 c, g dbSNP:138239732
1129 1129 c, g, t dbSNP:150430942
1130 1130 a, g, t dbSNP:140290452
1131 1131 c, t dbSNP:148039385
1132 1132 a, g dbSNP:777429499
1140 1140 a, g dbSNP:758070959
1141 1141 g, t dbSNP:200524093
1143 1143 a, g dbSNP:752458256
1150 1150 a, c, g, t dbSNP:199900092
1152 1152 g, t dbSNP:201203591
1157 1157 c, t dbSNP:768015132
1158 1158 a, g dbSNP:200844516
1173 1173 a, g dbSNP:774421614
1176 1176 c, t dbSNP:768736111
1177 1177 a, c, g, t dbSNP:140440387
1178 1178 a, g dbSNP:375160369
1192 1192 c, g dbSNP:372514243
1194 1194 a, g dbSNP:767040811
1201 1201 a, g dbSNP:746938291
1209 1209 g, t dbSNP:777411023
1210 1210 a, g dbSNP:368434498
1213 1213 c, t dbSNP:752364126
1225 1225 a, c dbSNP:778754506
1236 1236 a, c dbSNP:754605848
1238 1238 a, g dbSNP:750756265
1239 1239 g, t dbSNP:145534922
1262 1262 g, t dbSNP:762323585
1273 1273 a, g dbSNP:545887392
1287 1287 a, g dbSNP:545737929

Target ORF information:

RefSeq Version NM_145046
Organism Homo sapiens (human)
Definition Homo sapiens calreticulin 3 (CALR3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_145046

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGCCCGGG CTTTGGTCCA GCTCTGGGCC ATATGCATGC TGCGAGTGGC GCTGGCTACC 
GTCTATTTCC AAGAGGAATT TCTAGACGGA GAGCATTGGA GAAACCGATG GTTGCAGTCC
ACCAATGACT CCCGATTTGG GCATTTTAGA CTTTCGTCGG GCAAGTTTTA TGGTCATAAA
GAGAAAGATA AAGGTCTGCA AACCACTCAG AATGGCCGAT TCTATGCCAT CTCTGCACGC
TTCAAACCGT TCAGCAATAA AGGGAAAACT CTGGTTATTC AGTACACAGT AAAACATGAG
CAGAAGATGG ACTGTGGAGG GGGCTACATT AAGGTCTTTC CTGCAGACAT TGACCAGAAG
AACCTGAATG GAAAATCGCA GTACTATATT ATGTTTGGAC CCGATATTTG TGGATTTGAT
ATCAAGAAAG TTCATGTTAT TTTACATTTC AAGAATAAGT ATCACGAAAA CAAGAAACTG
ATCAGGTGTA AGGTTGATGG CTTCACACAC CTGTACACTC TAATTTTAAG ACCAGATCTT
TCTTATGATG TGAAAATTGA TGGTCAGTCA ATTGAATCCG GCAGCATAGA GTACGACTGG
AACTTAACAT CACTCAAGAA GGAAACGTCC CCGGCAGAAT CGAAGGATTG GGAACAGACT
AAAGACAACA AAGCCCAGGA CTGGGAGAAG CATTTTCTGG ACGCCAGCAC CAGCAAGCAG
AGCGACTGGA ACGGTGACCT GGATGGGGAC TGGCCAGCGC CGATGCTCCA GAAGCCCCCG
TACCAGGATG GCCTGAAACC AGAAGGTATT CATAAAGACG TCTGGCTCCA CCGTAAGATG
AAGAATACCG ACTATTTGAC GCAGTATGAC CTCTCAGAAT TTGAGAACAT TGGTGCCATT
GGCCTGGAGC TTTGGCAGGT GAGATCTGGA ACCATTTTTG ATAACTTTCT GATCACAGAT
GATGAAGAGT ACGCAGATAA TTTTGGCAAG GCCACCTGGG GCGAAACCAA GGGTCCAGAA
AGGGAGATGG ATGCCATACA GGCCAAGGAG GAAATGAAGA AGGCCCGCGA GGAAGAGGAG
GAAGAGCTGC TGTCGGGAAA AATTAACAGG CACGAACATT ACTTCAATCA ATTTCACAGA
AGGAATGAAC TTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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