||ORF Nucleotide Sequence (Length: 411bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AF531307.1.
On or before Sep 20, 2006 this sequence version replaced
gi:113431186, gi:22748792, gi:19743832.
Summary: Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. This structure consists of approximately 146 bp of DNA
wrapped around a nucleosome, an octamer composed of pairs of each
of the four core histones (H2A, H2B, H3, and H4). The chromatin
fiber is further compacted through the interaction of a linker
histone, H1, with the DNA between the nucleosomes to form higher
order chromatin structures. This gene is intronless and encodes a
replication-dependent histone that is a member of the histone H3
family. Transcripts from this gene lack polyA tails; instead, they
contain a palindromic termination element. This gene is found in a
histone cluster on chromosome 1. This gene is one of four histone
genes in the cluster that are duplicated; this record represents
the telomeric copy. [provided by RefSeq, Aug 2015].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
replication-dependent histone :: PMID: 12408966
COMPLETENESS: complete on the 3' end.