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EDARADD EDAR-associated death domain [Homo sapiens (human)]

Gene Symbol EDARADD
Entrez Gene ID 128178
Full Name EDAR-associated death domain
Synonyms ECTD11A, ECTD11B, ED3, EDA3
General protein information
Preferred Names
ectodysplasin-A receptor-associated adapter protein
Names
ectodysplasin-A receptor-associated adapter protein
crinkled homolog
EDAR-associated death domain protein
ectodysplasia A receptor associated death domain
ectodysplasin A receptor associated adapter protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q42.3

Summary This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

606603

Disorder Html: Ectodermal dysplasia, anhidrotic, autosomal recessive, 224900 (3);
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu19463 NM_145861 Homo sapiens EDAR-associated death domain (EDARADD), transcript variant A, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00
OHu16488 NM_080738 Homo sapiens EDAR-associated death domain (EDARADD), transcript variant B, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu19463D
Sequence Information ORF Nucleotide Sequence (Length: 648bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ectodysplasin-A receptor-associated adapter protein isoform A
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL354693.6, AY028913.1 and AL136105.9. This sequence is a reference standard in the RefSeqGene project. On Jul 24, 2007 this sequence version replaced gi:22325374. Summary: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (A) encodes a longer isoform (A). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY028913.1, BC128082.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
ATGGGCCTCA GGACGACTAA ACAGATGGGG AGAGGCACTA AAGCTCCTGG TCACCAAGAG 
GATCATATGG TAAAGGAACC AGTGGAAGAC ACAGACCCTA GCACTTTATC CTTTAATATG
TCAGACAAAT ATCCCATTCA AGATACGGAA CTCCCTAAAG CTGAAGAATG TGATACAATT
ACTTTGAACT GCCCACGAAA TTCAGATATG AAAAATCAGG GAGAAGAAAA TGGCTTTCCA
GATAGCACTG GAGATCCTCT TCCAGAGATC AGCAAGGACA ACTCCTGCAA AGAAAACTGT
ACTTGTTCCT CCTGCTTGCT CCGGGCCCCC ACCATAAGTG ACTTGCTCAA TGATCAGGAC
TTACTAGACG TGATCAGGAT AAAGCTGGAT CCGTGTCACC CAACGGTGAA AAACTGGAGG
AATTTTGCAA GCAAATGGGG GATGTCCTAT GACGAATTGT GCTTCCTGGA GCAGAGGCCA
CAGAGCCCCA CCTTGGAGTT CTTGCTCCGG AACAGTCAGA GGACGGTGGG CCAGCTGATG
GAGCTCTGCA GGCTCTACCA CAGGGCCGAC GTGGAGAAGG TTCTGCGCAG GTGGGTGGAC
GAGGAGTGGC CCAAGCGGGA GCGTGGAGAC CCCTCCAGGC ACTTCTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_665860.2
CDS66..713
Misc Feature(1)42..44(+)
Misc Feature(2)459..662(+)
Exon (1)1..126
Gene:EDARADD
Gene Synonym:
Exon (2)127..185
Gene:EDARADD
Gene Synonym:
Exon (3)186..225
Gene:EDARADD
Gene Synonym:
Exon (4)226..284
Gene:EDARADD
Gene Synonym:
Exon (5)285..330
Gene:EDARADD
Gene Synonym:
Exon (6)331..2772
Gene:EDARADD
Gene Synonym:
Translation
Position Chain Variation Link
6 6 a, c dbSNP:779610118
19 19 c, t dbSNP:746558281
34 34 c, t dbSNP:374105308
39 39 a, c dbSNP:753243751
63 63 a, g, t dbSNP:79233817
66 66 a, g dbSNP:750440434
72 72 c, g dbSNP:758261427
79 79 c, t dbSNP:779645902
80 80 a, g dbSNP:780639273
84 84 a, g dbSNP:768710770
87 87 c, g dbSNP:144687140
90 90 a, g dbSNP:748205202
92 92 a, g, t dbSNP:966365
93 93 c, g dbSNP:749732456
103 103 c, g dbSNP:771484831
108 108 a, g dbSNP:148192841
110 110 a, t dbSNP:183580795
125 125 a, g dbSNP:60808129
129 129 c, t dbSNP:762357435
137 137 a, t dbSNP:770542352
148 148 g, t dbSNP:200569815
161 161 a, c dbSNP:773740123
166 166 g, t dbSNP:374625285
170 170 c, t dbSNP:540466096
173 173 a, g dbSNP:565166177
180 180 a, g dbSNP:759461234
193 193 a, g dbSNP:775459429
196 196 a, g dbSNP:760445293
209 209 c, t dbSNP:763940320
211 211 c, t dbSNP:753577262
212 212 a, g dbSNP:146108503
226 226 c, t dbSNP:761543653
228 228 a, g dbSNP:765466865
238 238 a, t dbSNP:773355501
254 254 c, t dbSNP:763121649
261 261 c, t dbSNP:766500689
264 264 a, t dbSNP:751704449
267 267 c, t dbSNP:368460579
296 296 c, t dbSNP:773065240
307 307 a, t dbSNP:763211638
311 311 c, t dbSNP:766731640
319 319 a, t dbSNP:376772514
323 323 c, t dbSNP:138967527
331 331 -, g dbSNP:750512955
343 343 a, c dbSNP:534068767
347 347 c, t dbSNP:373971442
359 359 a, t dbSNP:762203601
363 363 c, t dbSNP:765992938
373 373 c, t dbSNP:114632254
386 386 a, c dbSNP:754505568
387 387 c, t dbSNP:147249573
388 388 a, g dbSNP:752275345
414 414 a, g dbSNP:755966826
420 420 c, g dbSNP:777899133
430 430 g, t dbSNP:121908116
434 434 c, t dbSNP:604070
435 435 a, g dbSNP:147501905
440 440 c, t dbSNP:779277524
443 443 g, t dbSNP:376972393
456 456 c, g dbSNP:772349212
458 458 a, g dbSNP:139996586
463 463 -, accca dbSNP:758607876
464 464 c, t dbSNP:760843174
467 467 -, aacggt dbSNP:397515575
469 469 c, t dbSNP:769122607
470 470 a, g dbSNP:777172467
494 494 a, c dbSNP:199965336
515 515 c, t dbSNP:369614195
518 518 c, t dbSNP:773579559
519 519 a, g dbSNP:74315309
520 520 a, c dbSNP:777298254
522 522 c, t dbSNP:143891636
526 526 a, g dbSNP:201032777
530 530 c, t dbSNP:767229616
533 533 a, g dbSNP:752115447
542 542 a, g dbSNP:755696159
551 551 c, t dbSNP:373326410
557 557 c, g dbSNP:371337563
558 558 c, t dbSNP:753890063
574 574 a, g dbSNP:757261515
586 586 c, g dbSNP:778797256
590 590 a, g dbSNP:377531010
592 592 c, t dbSNP:758511689
596 596 a, c dbSNP:780366105
616 616 a, g dbSNP:747038830
626 626 c, t dbSNP:768783242
630 630 a, g dbSNP:371177909
632 632 c, g, t dbSNP:373028114
633 633 a, g dbSNP:748587639
635 635 c, t dbSNP:200017138
636 636 a, g dbSNP:375789023
643 643 a, g dbSNP:773408614
651 651 c, t dbSNP:763414523
652 652 a, g dbSNP:483352767
665 665 c, g, t dbSNP:74942492
666 666 a, g dbSNP:763626415
668 668 a, g dbSNP:374279273
680 680 a, g dbSNP:753408117
681 681 c, t dbSNP:757216585
682 682 a, g dbSNP:765300638
687 687 c, t dbSNP:750157040
688 688 a, c, g dbSNP:376731607
697 697 c, t dbSNP:747324152
698 698 c, t dbSNP:755197423
707 707 -, c dbSNP:780323827
711 711 c, t dbSNP:781199161
712 712 a, g dbSNP:144235068
722 722 c, t dbSNP:770253410
725 725 c, t dbSNP:568663942
727 727 c, t dbSNP:749600700
731 731 c, t dbSNP:771390820
734 734 c, t dbSNP:774580843
737 737 c, g dbSNP:760342049
743 743 c, t dbSNP:768449995
744 744 a, g dbSNP:776244509
748 748 a, g dbSNP:761452687
749 749 c, t dbSNP:765066608
802 802 c, t dbSNP:757623127
814 814 a, g dbSNP:774204933
816 816 a, g dbSNP:759399160
829 829 a, c dbSNP:771924946
832 832 a, g dbSNP:766538054
838 838 c, t dbSNP:765675921
842 842 a, g dbSNP:79578216
875 875 c, t dbSNP:530109023
901 901 c, t dbSNP:554006482
905 905 c, t dbSNP:572424730
908 908 g, t dbSNP:775159272
985 985 a, g dbSNP:760609411
991 991 c, g dbSNP:539403998
998 998 a, g dbSNP:142266831
1019 1019 c, t dbSNP:576451942
1033 1033 -, a dbSNP:557974993
1062 1062 c, t dbSNP:753919866
1071 1071 a, g dbSNP:761943296
1114 1114 c, t dbSNP:765444080
1129 1129 c, t dbSNP:750580319
1130 1130 a, g dbSNP:189781826
1135 1135 c, t dbSNP:780419146
1143 1143 a, g dbSNP:562522582
1218 1218 a, g dbSNP:11544520
1224 1224 c, t dbSNP:11544492
1225 1225 c, t dbSNP:574721648
1235 1235 a, t dbSNP:11544488
1240 1240 c, g dbSNP:751900812
1272 1272 a, g dbSNP:542062444
1282 1282 c, t dbSNP:11544490
1292 1292 g, t dbSNP:11544502
1310 1310 a, g dbSNP:755480710
1323 1323 a, g dbSNP:11544508
1341 1341 a, g dbSNP:183153044
1348 1348 a, g dbSNP:781597200
1349 1349 a, g dbSNP:527593438
1356 1356 a, t dbSNP:545805733
1365 1365 c, t dbSNP:748792724
1374 1374 c, t dbSNP:564154544
1377 1377 a, g dbSNP:770632805
1391 1391 a, c dbSNP:61740488
1394 1394 c, t dbSNP:549879586
1395 1395 a, g dbSNP:61740486
1400 1400 a, g dbSNP:548412628
1402 1402 g, t dbSNP:11544516
1407 1407 a, g dbSNP:11544518
1409 1409 c, g dbSNP:529416761
1410 1410 g, t dbSNP:767911111
1414 1414 c, t dbSNP:11544505
1432 1432 c, t dbSNP:188977509
1437 1437 a, g dbSNP:151018330
1438 1438 c, t dbSNP:11544493
1459 1459 g, t dbSNP:745456566
1463 1463 a, t dbSNP:11544496
1466 1466 a, g dbSNP:11544515
1470 1470 a, c dbSNP:201197563
1477 1477 a, c dbSNP:11544500
1478 1478 a, g dbSNP:573814452
1491 1491 a, c dbSNP:11544501
1492 1492 g, t dbSNP:11544511
1532 1532 a, g dbSNP:557865025
1551 1551 c, t dbSNP:760424297
1576 1576 c, t dbSNP:570062425
1577 1577 a, g dbSNP:776501424
1619 1619 c, t dbSNP:778457987
1653 1653 a, c dbSNP:368740808
1669 1669 c, t dbSNP:201986008
1671 1671 c, t dbSNP:555798195
1679 1679 a, g dbSNP:61740489
1680 1680 a, g, t dbSNP:193138062
1689 1689 a, g dbSNP:773303070
1701 1701 a, g dbSNP:554050493
1717 1717 a, g dbSNP:750918090
1725 1725 a, g dbSNP:572366811
1734 1734 c, t dbSNP:139959221
1748 1748 a, g dbSNP:758471217
1762 1762 c, t dbSNP:143397265
1771 1771 c, t dbSNP:766552460
1786 1786 c, g dbSNP:751932339
1843 1843 c, t dbSNP:531300947
1844 1844 a, g dbSNP:146714861
1887 1887 a, g dbSNP:61511776
1911 1911 a, c dbSNP:528968509
1917 1917 c, t dbSNP:185247485
1918 1918 a, g dbSNP:188565995
2010 2010 a, t dbSNP:533426728
2016 2016 g, t dbSNP:780044781
2017 2017 a, t dbSNP:191629037
2023 2023 c, t dbSNP:561111220
2031 2031 c, t dbSNP:537425556
2058 2058 a, c dbSNP:555480713
2125 2125 g, t dbSNP:567752682
2129 2129 a, t dbSNP:753187987
2151 2151 c, t dbSNP:201710490
2152 2152 a, g dbSNP:61736812
2171 2171 -, t dbSNP:372417387
2176 2176 -, gga dbSNP:537201596
2202 2202 a, c dbSNP:79469181
2222 2222 a, g dbSNP:572303183
2248 2248 c, t dbSNP:202115969
2275 2275 c, t dbSNP:7513402
2296 2296 a, g dbSNP:558001888
2306 2306 g, t dbSNP:61736989
2308 2308 c, t dbSNP:367771921
2314 2314 a, c, g dbSNP:3916983
2326 2326 c, t dbSNP:61737025
2367 2367 g, t dbSNP:754759239
2368 2368 a, c dbSNP:531411750
2399 2399 a, g dbSNP:563864823
2435 2435 c, t dbSNP:559506851
2473 2473 a, g dbSNP:533536044
2483 2483 a, c dbSNP:1065605
2500 2500 c, t dbSNP:6428955
2540 2540 a, g dbSNP:79905520
2548 2548 a, g dbSNP:563960898
2562 2562 c, t dbSNP:748029668
2564 2564 g, t dbSNP:531120259
2587 2587 -, t dbSNP:770456483
2599 2599 c, t dbSNP:534831555
2600 2600 a, g dbSNP:114783553
2617 2617 a, g dbSNP:567689874
2619 2619 c, g dbSNP:535105739
2636 2636 c, t dbSNP:773247620
2645 2645 c, t dbSNP:773795115
2663 2663 c, t dbSNP:547079176
2664 2664 c, g dbSNP:571789874
2668 2668 a, t dbSNP:144943032
2675 2675 c, t dbSNP:111987152
2676 2676 a, g dbSNP:576279644
2686 2686 c, g dbSNP:766608566
2698 2698 a, g dbSNP:774501424
2708 2708 a, g dbSNP:759808244
2714 2714 a, g dbSNP:149042380
2721 2721 a, g dbSNP:184215335
2729 2729 g, t dbSNP:573337924
2765 2765 c, t dbSNP:759188384
2771 2771 -, ag dbSNP:148246290
2772 2772 a, g dbSNP:200288312

Target ORF information:

RefSeq Version NM_145861
Organism Homo sapiens (human)
Definition Homo sapiens EDAR-associated death domain (EDARADD), transcript variant A, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_145861

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGGGCCTCA GGACGACTAA ACAGATGGGG AGAGGCACTA AAGCTCCTGG TCACCAAGAG 
GATCATATGG TAAAGGAACC AGTGGAAGAC ACAGACCCTA GCACTTTATC CTTTAATATG
TCAGACAAAT ATCCCATTCA AGATACGGAA CTCCCTAAAG CTGAAGAATG TGATACAATT
ACTTTGAACT GCCCACGAAA TTCAGATATG AAAAATCAGG GAGAAGAAAA TGGCTTTCCA
GATAGCACTG GAGATCCTCT TCCAGAGATC AGCAAGGACA ACTCCTGCAA AGAAAACTGT
ACTTGTTCCT CCTGCTTGCT CCGGGCCCCC ACCATAAGTG ACTTGCTCAA TGATCAGGAC
TTACTAGACG TGATCAGGAT AAAGCTGGAT CCGTGTCACC CAACGGTGAA AAACTGGAGG
AATTTTGCAA GCAAATGGGG GATGTCCTAT GACGAATTGT GCTTCCTGGA GCAGAGGCCA
CAGAGCCCCA CCTTGGAGTT CTTGCTCCGG AACAGTCAGA GGACGGTGGG CCAGCTGATG
GAGCTCTGCA GGCTCTACCA CAGGGCCGAC GTGGAGAAGG TTCTGCGCAG GTGGGTGGAC
GAGGAGTGGC CCAAGCGGGA GCGTGGAGAC CCCTCCAGGC ACTTCTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu16488D
Sequence Information ORF Nucleotide Sequence (Length: 618bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ectodysplasin-A receptor-associated adapter protein isoform B
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096339.1 and BC006533.2. On Jul 24, 2007 this sequence version replaced gi:22325373. Summary: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (B) differs in the 5' region compared to variant A. It encodes an isoform (B) that contains a distinct and shorter N-terminus, as compared to isoform (A). ##Evidence-Data-START## Transcript exon combination :: AK096339.1, BC006533.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
ATGGCTTCAC CGGACGACCC TCTGCGCGCA GATCATATGG TAAAGGAACC AGTGGAAGAC 
ACAGACCCTA GCACTTTATC CTTTAATATG TCAGACAAAT ATCCCATTCA AGATACGGAA
CTCCCTAAAG CTGAAGAATG TGATACAATT ACTTTGAACT GCCCACGAAA TTCAGATATG
AAAAATCAGG GAGAAGAAAA TGGCTTTCCA GATAGCACTG GAGATCCTCT TCCAGAGATC
AGCAAGGACA ACTCCTGCAA AGAAAACTGT ACTTGTTCCT CCTGCTTGCT CCGGGCCCCC
ACCATAAGTG ACTTGCTCAA TGATCAGGAC TTACTAGACG TGATCAGGAT AAAGCTGGAT
CCGTGTCACC CAACGGTGAA AAACTGGAGG AATTTTGCAA GCAAATGGGG GATGTCCTAT
GACGAATTGT GCTTCCTGGA GCAGAGGCCA CAGAGCCCCA CCTTGGAGTT CTTGCTCCGG
AACAGTCAGA GGACGGTGGG CCAGCTGATG GAGCTCTGCA GGCTCTACCA CAGGGCCGAC
GTGGAGAAGG TTCTGCGCAG GTGGGTGGAC GAGGAGTGGC CCAAGCGGGA GCGTGGAGAC
CCCTCCAGGC ACTTCTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_542776.1
CDS215..832
Misc Feature(1)203..205(+)
Misc Feature(2)578..781(+)
Exon (1)1..245
Gene:EDARADD
Gene Synonym:
Exon (2)246..304
Gene:EDARADD
Gene Synonym:
Exon (3)305..344
Gene:EDARADD
Gene Synonym:
Exon (4)345..403
Gene:EDARADD
Gene Synonym:
Exon (5)404..449
Gene:EDARADD
Gene Synonym:
Exon (6)450..2891
Gene:EDARADD
Gene Synonym:
Translation
Position Chain Variation Link
12 12 c, t dbSNP:763988349
36 36 c, g dbSNP:532876611
39 39 a, t dbSNP:753773253
97 97 a, g dbSNP:370241361
104 104 c, g dbSNP:767667201
181 181 c, t dbSNP:142921113
184 184 c, t dbSNP:756335609
200 200 c, t dbSNP:777775002
211 211 c, t dbSNP:749397194
212 212 g, t dbSNP:201123188
214 214 a, c dbSNP:774958692
233 233 c, g, t dbSNP:200100313
240 240 a, g dbSNP:776415213
242 242 a, g, t dbSNP:368596664
248 248 c, t dbSNP:762357435
256 256 a, t dbSNP:770542352
267 267 g, t dbSNP:200569815
280 280 a, c dbSNP:773740123
285 285 g, t dbSNP:374625285
289 289 c, t dbSNP:540466096
292 292 a, g dbSNP:565166177
299 299 a, g dbSNP:759461234
312 312 a, g dbSNP:775459429
315 315 a, g dbSNP:760445293
328 328 c, t dbSNP:763940320
330 330 c, t dbSNP:753577262
331 331 a, g dbSNP:146108503
345 345 c, t dbSNP:761543653
347 347 a, g dbSNP:765466865
357 357 a, t dbSNP:773355501
373 373 c, t dbSNP:763121649
380 380 c, t dbSNP:766500689
383 383 a, t dbSNP:751704449
386 386 c, t dbSNP:368460579
415 415 c, t dbSNP:773065240
426 426 a, t dbSNP:763211638
430 430 c, t dbSNP:766731640
438 438 a, t dbSNP:376772514
442 442 c, t dbSNP:138967527
450 450 -, g dbSNP:750512955
462 462 a, c dbSNP:534068767
466 466 c, t dbSNP:373971442
478 478 a, t dbSNP:762203601
482 482 c, t dbSNP:765992938
492 492 c, t dbSNP:114632254
505 505 a, c dbSNP:754505568
506 506 c, t dbSNP:147249573
507 507 a, g dbSNP:752275345
533 533 a, g dbSNP:755966826
539 539 c, g dbSNP:777899133
549 549 g, t dbSNP:121908116
553 553 c, t dbSNP:604070
554 554 a, g dbSNP:147501905
559 559 c, t dbSNP:779277524
562 562 g, t dbSNP:376972393
575 575 c, g dbSNP:772349212
577 577 a, g dbSNP:139996586
582 582 -, accca dbSNP:758607876
583 583 c, t dbSNP:760843174
586 586 -, aacggt dbSNP:397515575
588 588 c, t dbSNP:769122607
589 589 a, g dbSNP:777172467
613 613 a, c dbSNP:199965336
634 634 c, t dbSNP:369614195
637 637 c, t dbSNP:773579559
638 638 a, g dbSNP:74315309
639 639 a, c dbSNP:777298254
641 641 c, t dbSNP:143891636
645 645 a, g dbSNP:201032777
649 649 c, t dbSNP:767229616
652 652 a, g dbSNP:752115447
661 661 a, g dbSNP:755696159
670 670 c, t dbSNP:373326410
676 676 c, g dbSNP:371337563
677 677 c, t dbSNP:753890063
693 693 a, g dbSNP:757261515
705 705 c, g dbSNP:778797256
709 709 a, g dbSNP:377531010
711 711 c, t dbSNP:758511689
715 715 a, c dbSNP:780366105
735 735 a, g dbSNP:747038830
745 745 c, t dbSNP:768783242
749 749 a, g dbSNP:371177909
751 751 c, g, t dbSNP:373028114
752 752 a, g dbSNP:748587639
754 754 c, t dbSNP:200017138
755 755 a, g dbSNP:375789023
762 762 a, g dbSNP:773408614
770 770 c, t dbSNP:763414523
771 771 a, g dbSNP:483352767
784 784 c, g, t dbSNP:74942492
785 785 a, g dbSNP:763626415
787 787 a, g dbSNP:374279273
799 799 a, g dbSNP:753408117
800 800 c, t dbSNP:757216585
801 801 a, g dbSNP:765300638
806 806 c, t dbSNP:750157040
807 807 a, c, g dbSNP:376731607
816 816 c, t dbSNP:747324152
817 817 c, t dbSNP:755197423
826 826 -, c dbSNP:780323827
830 830 c, t dbSNP:781199161
831 831 a, g dbSNP:144235068
841 841 c, t dbSNP:770253410
844 844 c, t dbSNP:568663942
846 846 c, t dbSNP:749600700
850 850 c, t dbSNP:771390820
853 853 c, t dbSNP:774580843
856 856 c, g dbSNP:760342049
862 862 c, t dbSNP:768449995
863 863 a, g dbSNP:776244509
867 867 a, g dbSNP:761452687
868 868 c, t dbSNP:765066608
921 921 c, t dbSNP:757623127
933 933 a, g dbSNP:774204933
935 935 a, g dbSNP:759399160
948 948 a, c dbSNP:771924946
951 951 a, g dbSNP:766538054
957 957 c, t dbSNP:765675921
961 961 a, g dbSNP:79578216
994 994 c, t dbSNP:530109023
1020 1020 c, t dbSNP:554006482
1024 1024 c, t dbSNP:572424730
1027 1027 g, t dbSNP:775159272
1104 1104 a, g dbSNP:760609411
1110 1110 c, g dbSNP:539403998
1117 1117 a, g dbSNP:142266831
1138 1138 c, t dbSNP:576451942
1152 1152 -, a dbSNP:557974993
1181 1181 c, t dbSNP:753919866
1190 1190 a, g dbSNP:761943296
1233 1233 c, t dbSNP:765444080
1248 1248 c, t dbSNP:750580319
1249 1249 a, g dbSNP:189781826
1254 1254 c, t dbSNP:780419146
1262 1262 a, g dbSNP:562522582
1337 1337 a, g dbSNP:11544520
1343 1343 c, t dbSNP:11544492
1344 1344 c, t dbSNP:574721648
1354 1354 a, t dbSNP:11544488
1359 1359 c, g dbSNP:751900812
1391 1391 a, g dbSNP:542062444
1401 1401 c, t dbSNP:11544490
1411 1411 g, t dbSNP:11544502
1429 1429 a, g dbSNP:755480710
1442 1442 a, g dbSNP:11544508
1460 1460 a, g dbSNP:183153044
1467 1467 a, g dbSNP:781597200
1468 1468 a, g dbSNP:527593438
1475 1475 a, t dbSNP:545805733
1484 1484 c, t dbSNP:748792724
1493 1493 c, t dbSNP:564154544
1496 1496 a, g dbSNP:770632805
1510 1510 a, c dbSNP:61740488
1513 1513 c, t dbSNP:549879586
1514 1514 a, g dbSNP:61740486
1519 1519 a, g dbSNP:548412628
1521 1521 g, t dbSNP:11544516
1526 1526 a, g dbSNP:11544518
1528 1528 c, g dbSNP:529416761
1529 1529 g, t dbSNP:767911111
1533 1533 c, t dbSNP:11544505
1551 1551 c, t dbSNP:188977509
1556 1556 a, g dbSNP:151018330
1557 1557 c, t dbSNP:11544493
1578 1578 g, t dbSNP:745456566
1582 1582 a, t dbSNP:11544496
1585 1585 a, g dbSNP:11544515
1589 1589 a, c dbSNP:201197563
1596 1596 a, c dbSNP:11544500
1597 1597 a, g dbSNP:573814452
1610 1610 a, c dbSNP:11544501
1611 1611 g, t dbSNP:11544511
1651 1651 a, g dbSNP:557865025
1670 1670 c, t dbSNP:760424297
1695 1695 c, t dbSNP:570062425
1696 1696 a, g dbSNP:776501424
1738 1738 c, t dbSNP:778457987
1772 1772 a, c dbSNP:368740808
1788 1788 c, t dbSNP:201986008
1790 1790 c, t dbSNP:555798195
1798 1798 a, g dbSNP:61740489
1799 1799 a, g, t dbSNP:193138062
1808 1808 a, g dbSNP:773303070
1820 1820 a, g dbSNP:554050493
1836 1836 a, g dbSNP:750918090
1844 1844 a, g dbSNP:572366811
1853 1853 c, t dbSNP:139959221
1867 1867 a, g dbSNP:758471217
1881 1881 c, t dbSNP:143397265
1890 1890 c, t dbSNP:766552460
1905 1905 c, g dbSNP:751932339
1962 1962 c, t dbSNP:531300947
1963 1963 a, g dbSNP:146714861
2006 2006 a, g dbSNP:61511776
2030 2030 a, c dbSNP:528968509
2036 2036 c, t dbSNP:185247485
2037 2037 a, g dbSNP:188565995
2129 2129 a, t dbSNP:533426728
2135 2135 g, t dbSNP:780044781
2136 2136 a, t dbSNP:191629037
2142 2142 c, t dbSNP:561111220
2150 2150 c, t dbSNP:537425556
2177 2177 a, c dbSNP:555480713
2244 2244 g, t dbSNP:567752682
2248 2248 a, t dbSNP:753187987
2270 2270 c, t dbSNP:201710490
2271 2271 a, g dbSNP:61736812
2290 2290 -, t dbSNP:372417387
2295 2295 -, gga dbSNP:537201596
2321 2321 a, c dbSNP:79469181
2341 2341 a, g dbSNP:572303183
2367 2367 c, t dbSNP:202115969
2394 2394 c, t dbSNP:7513402
2415 2415 a, g dbSNP:558001888
2425 2425 g, t dbSNP:61736989
2427 2427 c, t dbSNP:367771921
2433 2433 a, c, g dbSNP:3916983
2445 2445 c, t dbSNP:61737025
2486 2486 g, t dbSNP:754759239
2487 2487 a, c dbSNP:531411750
2518 2518 a, g dbSNP:563864823
2554 2554 c, t dbSNP:559506851
2592 2592 a, g dbSNP:533536044
2602 2602 a, c dbSNP:1065605
2619 2619 c, t dbSNP:6428955
2659 2659 a, g dbSNP:79905520
2667 2667 a, g dbSNP:563960898
2681 2681 c, t dbSNP:748029668
2683 2683 g, t dbSNP:531120259
2706 2706 -, t dbSNP:770456483
2718 2718 c, t dbSNP:534831555
2719 2719 a, g dbSNP:114783553
2736 2736 a, g dbSNP:567689874
2738 2738 c, g dbSNP:535105739
2755 2755 c, t dbSNP:773247620
2764 2764 c, t dbSNP:773795115
2782 2782 c, t dbSNP:547079176
2783 2783 c, g dbSNP:571789874
2787 2787 a, t dbSNP:144943032
2794 2794 c, t dbSNP:111987152
2795 2795 a, g dbSNP:576279644
2805 2805 c, g dbSNP:766608566
2817 2817 a, g dbSNP:774501424
2827 2827 a, g dbSNP:759808244
2833 2833 a, g dbSNP:149042380
2840 2840 a, g dbSNP:184215335
2848 2848 g, t dbSNP:573337924
2884 2884 c, t dbSNP:759188384
2890 2890 -, ag dbSNP:148246290
2891 2891 a, g dbSNP:200288312

Target ORF information:

RefSeq Version NM_080738
Organism Homo sapiens (human)
Definition Homo sapiens EDAR-associated death domain (EDARADD), transcript variant B, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_080738

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGGCTTCAC CGGACGACCC TCTGCGCGCA GATCATATGG TAAAGGAACC AGTGGAAGAC 
ACAGACCCTA GCACTTTATC CTTTAATATG TCAGACAAAT ATCCCATTCA AGATACGGAA
CTCCCTAAAG CTGAAGAATG TGATACAATT ACTTTGAACT GCCCACGAAA TTCAGATATG
AAAAATCAGG GAGAAGAAAA TGGCTTTCCA GATAGCACTG GAGATCCTCT TCCAGAGATC
AGCAAGGACA ACTCCTGCAA AGAAAACTGT ACTTGTTCCT CCTGCTTGCT CCGGGCCCCC
ACCATAAGTG ACTTGCTCAA TGATCAGGAC TTACTAGACG TGATCAGGAT AAAGCTGGAT
CCGTGTCACC CAACGGTGAA AAACTGGAGG AATTTTGCAA GCAAATGGGG GATGTCCTAT
GACGAATTGT GCTTCCTGGA GCAGAGGCCA CAGAGCCCCA CCTTGGAGTT CTTGCTCCGG
AACAGTCAGA GGACGGTGGG CCAGCTGATG GAGCTCTGCA GGCTCTACCA CAGGGCCGAC
GTGGAGAAGG TTCTGCGCAG GTGGGTGGAC GAGGAGTGGC CCAAGCGGGA GCGTGGAGAC
CCCTCCAGGC ACTTCTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.