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COMP cDNA ORF clone, Homo sapiens (human)

Gene Symbol COMP
Entrez Gene ID 1311
Full Name cartilage oligomeric matrix protein
Synonyms EDM1, EPD1, MED, PSACH, THBS5
General protein information
Preferred Names
cartilage oligomeric matrix protein
Names
cartilage oligomeric matrix protein
TSP5
thrombospondin-5
pseudoachondroplasia (epiphyseal dysplasia 1, multiple)
cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple)
cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.1

Summary The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

600310

Disorder Html: Pseudoachondroplasia, 177170 (3); Epiphyseal dysplasia, multiple 1,





The following COMP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COMP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19189 NM_000095 Homo sapiens cartilage oligomeric matrix protein (COMP), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$265.30
$379.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu19189
Accession Version NM_000095.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2274bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product cartilage oligomeric matrix protein precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU120397.1, BC033676.1 and L32137.1. This sequence is a reference standard in the RefSeqGene project. On Dec 19, 2003 this sequence version replaced gi:4557482. Summary: The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223216.1, L32137.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGTCCCCG ACACCGCCTG CGTTCTTCTG CTCACCCTGG CTGCCCTCGG CGCGTCCGGA 
CAGGGCCAGA GCCCGTTGGG CTCAGACCTG GGCCCGCAGA TGCTTCGGGA ACTGCAGGAA
ACCAACGCGG CGCTGCAGGA CGTGCGGGAG CTGCTGCGGC AGCAGGTCAG GGAGATCACG
TTCCTGAAAA ACACGGTGAT GGAGTGTGAC GCGTGCGGGA TGCAGCAGTC AGTACGCACC
GGCCTACCCA GCGTGCGGCC CCTGCTCCAC TGCGCGCCCG GCTTCTGCTT CCCCGGCGTG
GCCTGCATCC AGACGGAGAG CGGCGCGCGC TGCGGCCCCT GCCCCGCGGG CTTCACGGGC
AACGGCTCGC ACTGCACCGA CGTCAACGAG TGCAACGCCC ACCCCTGCTT CCCCCGAGTC
CGCTGTATCA ACACCAGCCC GGGGTTCCGC TGCGAGGCTT GCCCGCCGGG GTACAGCGGC
CCCACCCACC AGGGCGTGGG GCTGGCTTTC GCCAAGGCCA ACAAGCAGGT TTGCACGGAC
ATCAACGAGT GTGAGACCGG GCAACATAAC TGCGTCCCCA ACTCCGTGTG CATCAACACC
CGGGGCTCCT TCCAGTGCGG CCCGTGCCAG CCCGGCTTCG TGGGCGACCA GGCGTCCGGC
TGCCAGCGGC GCGCACAGCG CTTCTGCCCC GACGGCTCGC CCAGCGAGTG CCACGAGCAT
GCAGACTGCG TCCTAGAGCG CGATGGCTCG CGGTCGTGCG TGTGTGCCGT TGGCTGGGCC
GGCAACGGGA TCCTCTGTGG TCGCGACACT GACCTAGACG GCTTCCCGGA CGAGAAGCTG
CGCTGCCCGG AGCGCCAGTG CCGTAAGGAC AACTGCGTGA CTGTGCCCAA CTCAGGGCAG
GAGGATGTGG ACCGCGATGG CATCGGAGAC GCCTGCGATC CGGATGCCGA CGGGGACGGG
GTCCCCAATG AAAAGGACAA CTGCCCGCTG GTGCGGAACC CAGACCAGCG CAACACGGAC
GAGGACAAGT GGGGCGATGC GTGCGACAAC TGCCGGTCCC AGAAGAACGA CGACCAAAAG
GACACAGACC AGGACGGCCG GGGCGATGCG TGCGACGACG ACATCGACGG CGACCGGATC
CGCAACCAGG CCGACAACTG CCCTAGGGTA CCCAACTCAG ACCAGAAGGA CAGTGATGGC
GATGGTATAG GGGATGCCTG TGACAACTGT CCCCAGAAGA GCAACCCGGA TCAGGCGGAT
GTGGACCACG ACTTTGTGGG AGATGCTTGT GACAGCGATC AAGACCAGGA TGGAGACGGA
CATCAGGACT CTCGGGACAA CTGTCCCACG GTGCCTAACA GTGCCCAGGA GGACTCAGAC
CACGATGGCC AGGGTGATGC CTGCGACGAC GACGACGACA ATGACGGAGT CCCTGACAGT
CGGGACAACT GCCGCCTGGT GCCTAACCCC GGCCAGGAGG ACGCGGACAG GGACGGCGTG
GGCGACGTGT GCCAGGACGA CTTTGATGCA GACAAGGTGG TAGACAAGAT CGACGTGTGT
CCGGAGAACG CTGAAGTCAC GCTCACCGAC TTCAGGGCCT TCCAGACAGT CGTGCTGGAC
CCGGAGGGTG ACGCGCAGAT TGACCCCAAC TGGGTGGTGC TCAACCAGGG AAGGGAGATC
GTGCAGACAA TGAACAGCGA CCCAGGCCTG GCTGTGGGTT ACACTGCCTT CAATGGCGTG
GACTTCGAGG GCACGTTCCA TGTGAACACG GTCACGGATG ACGACTATGC GGGCTTCATC
TTTGGCTACC AGGACAGCTC CAGCTTCTAC GTGGTCATGT GGAAGCAGAT GGAGCAAACG
TATTGGCAGG CGAACCCCTT CCGTGCTGTG GCCGAGCCTG GCATCCAACT CAAGGCTGTG
AAGTCTTCCA CAGGCCCCGG GGAACAGCTG CGGAACGCTC TGTGGCATAC AGGAGACACA
GAGTCCCAGG TGCGGCTGCT GTGGAAGGAC CCGCGAAACG TGGGTTGGAA GGACAAGAAG
TCCTATCGTT GGTTCCTGCA GCACCGGCCC CAAGTGGGCT ACATCAGGGT GCGATTCTAT
GAGGGCCCTG AGCTGGTGGC CGACAGCAAC GTGGTCTTGG ACACAACCAT GCGGGGTGGC
CGCCTGGGGG TCTTCTGCTT CTCCCAGGAG AACATCATCT GGGCCAACCT GCGTTACCGC
TGCAATGACA CCATCCCAGA GGACTATGAG ACCCATCAGC TGCGGCAAGC CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_000086.2
CDS37..2310
Misc Feature(1)100..294(+)
Misc Feature(2)121..255(+)
Misc Feature(3)415..522(+)
Misc Feature(4)415..468(+)
Misc Feature(5)574..684(+)
Misc Feature(6)574..633(+)
Misc Feature(7)817..936(+)
Misc Feature(8)838..936(+)
Misc Feature(9)841..927(+)
Misc Feature(10)937..1044(+)
Misc Feature(11)937..1044(+)
Misc Feature(12)937..1044(+)
Misc Feature(13)940..1044(+)
Misc Feature(14)940..1035(+)
Misc Feature(15)940..975(+)
Misc Feature(16)979..1035(+)
Misc Feature(17)1045..1113(+)
Misc Feature(18)1045..1113(+)
Misc Feature(19)1045..1113(+)
Misc Feature(20)1048..1104(+)
Misc Feature(21)1048..1104(+)
Misc Feature(22)1114..1221(+)
Misc Feature(23)1114..1221(+)
Misc Feature(24)1117..1152(+)
Misc Feature(25)1135..1143(+)
Misc Feature(26)1156..1212(+)
Misc Feature(27)1222..1290(+)
Misc Feature(28)1222..1290(+)
Misc Feature(29)1225..1404(+)
Misc Feature(30)1225..1281(+)
Misc Feature(31)1291..1404(+)
Misc Feature(32)1291..1404(+)
Misc Feature(33)1294..1335(+)
Misc Feature(34)1339..1395(+)
Misc Feature(35)1405..1512(+)
Misc Feature(36)1513..1620(+)
Misc Feature(37)1513..1608(+)
Misc Feature(38)1516..1620(+)
Misc Feature(39)1516..1551(+)
Misc Feature(40)1555..1590(+)
Misc Feature(41)1615..2307(+)
Misc Feature(42)1672..2274(+)
Exon (1)1..115
Gene:COMP
Gene Synonym:
Exon (2)116..201
Gene:COMP
Gene Synonym:
Exon (3)202..253
Gene:COMP
Gene Synonym:
Exon (4)254..426
Gene:COMP
Gene Synonym:
Exon (5)427..564
Gene:COMP
Gene Synonym:
Exon (6)565..639
Gene:COMP
Gene Synonym:
Exon (7)640..798
Gene:COMP
Gene Synonym:
Exon (8)799..903
Gene:COMP
Gene Synonym:
Exon (9)904..1011
Gene:COMP
Gene Synonym:
Exon (10)1012..1171
Gene:COMP
Gene Synonym:
Exon (11)1172..1290
Gene:COMP
Gene Synonym:
Exon (12)1291..1343
Gene:COMP
Gene Synonym:
Exon (13)1344..1525
Gene:COMP
Gene Synonym:
Exon (14)1526..1704
Gene:COMP
Gene Synonym:
Exon (15)1705..1753
Gene:COMP
Gene Synonym:
Exon (16)1754..1950
Gene:COMP
Gene Synonym:
Exon (17)1951..2123
Gene:COMP
Gene Synonym:
Exon (18)2124..2263
Gene:COMP
Gene Synonym:
Exon (19)2264..2452
Gene:COMP
Gene Synonym:
Translation
Position Chain Variation Link
17 17 c, t dbSNP:763184247
21 21 a, g dbSNP:775728364
22 22 c, t dbSNP:374273743
28 28 g, t dbSNP:186562511
29 29 a, c dbSNP:377427968
32 32 c, t dbSNP:770618707
34 34 a, c, g, t dbSNP:372647850
36 36 c, t dbSNP:758012211
43 43 c, g dbSNP:747780884
44 44 c, g dbSNP:778579333
47 47 a, c dbSNP:370458957
56 56 a, g dbSNP:753831272
69 69 c, t dbSNP:766271854
72 72 c, t dbSNP:756004591
84 84 c, t dbSNP:751611983
85 85 a, g dbSNP:764174833
90 90 g, t dbSNP:763087689
93 93 c, t dbSNP:752956065
94 94 a, g dbSNP:765574677
107 107 a, g dbSNP:759953553
108 108 c, g dbSNP:777322430
112 112 c, t dbSNP:771600027
123 123 c, t dbSNP:759794906
131 131 a, c dbSNP:754279636
148 148 c, t dbSNP:766794778
152 152 a, t dbSNP:369162037
154 154 a, g dbSNP:773766773
159 159 a, c dbSNP:771541405
162 162 c, t dbSNP:761363648
168 168 a, g dbSNP:377650362
172 172 c, t dbSNP:374010493
177 177 c, t dbSNP:748881562
214 214 a, t dbSNP:762658260
216 216 g, t dbSNP:775107337
231 231 a, g dbSNP:529891904
235 235 a, g dbSNP:142742836
237 237 a, c, g dbSNP:199553971
253 253 c, g dbSNP:746866867
259 259 c, t dbSNP:747012627
261 261 a, g dbSNP:773271062
271 271 a, c dbSNP:768907479
272 272 g, t dbSNP:578030956
283 283 a, c dbSNP:780242314
289 289 a, g dbSNP:558270243
291 291 a, g dbSNP:756371539
293 293 g, t dbSNP:538226042
303 303 c, g dbSNP:781667717
304 304 c, t dbSNP:757546301
311 311 c, t dbSNP:752108052
312 312 a, g dbSNP:778217484
315 315 a, c, g dbSNP:139319996
335 335 a, t dbSNP:764598641
338 338 -, ggc dbSNP:746962183
345 345 c, t dbSNP:759234100
348 348 c, g dbSNP:753431683
351 351 c, g dbSNP:766256710
360 360 c, t dbSNP:760526046
366 366 c, g dbSNP:773322606
375 375 c, g dbSNP:772168146
380 380 c, g dbSNP:761783627
393 393 a, g dbSNP:775643921
396 396 c, t dbSNP:150820366
399 399 c, t dbSNP:372321928
405 405 c, g, t dbSNP:771322380
409 409 g, t dbSNP:747401384
418 418 a, g dbSNP:143954978
423 423 a, c dbSNP:758922573
432 432 c, g dbSNP:200638121
435 435 a, c dbSNP:767476445
446 446 c, t dbSNP:757094319
447 447 c, t dbSNP:751553623
448 448 c, g dbSNP:763966726
458 458 g, t dbSNP:762894659
463 463 a, g dbSNP:776583689
475 475 c, t dbSNP:766383824
476 476 c, t dbSNP:778825368
477 477 a, c, g dbSNP:773412062
481 481 c, t dbSNP:767728967
489 489 c, t dbSNP:201389713
490 490 g, t dbSNP:748432425
491 491 a, g dbSNP:774739958
493 493 g, t dbSNP:769066350
500 500 a, c dbSNP:749746495
504 504 c, g, t dbSNP:202241721
507 507 g, t dbSNP:528922456
513 513 c, g dbSNP:780957814
522 522 c, g dbSNP:756891671
531 531 a, c dbSNP:751329471
536 536 a, g dbSNP:763887855
542 542 c, t dbSNP:758276062
547 547 a, g dbSNP:115338183
564 564 g, t dbSNP:766506948
585 585 a, g dbSNP:750524994
602 602 a, g dbSNP:199792797
609 609 c, t dbSNP:761946670
610 610 a, g dbSNP:751791404
620 620 c, g dbSNP:764412772
622 622 a, g dbSNP:763345173
624 624 a, g dbSNP:201165293
626 626 a, g dbSNP:770442870
630 630 c, t dbSNP:760059984
637 637 a, c dbSNP:776283041
638 638 c, g dbSNP:770473296
639 639 a, g dbSNP:746701204
641 641 a, g dbSNP:747740873
670 670 a, g dbSNP:774138872
679 679 c, g dbSNP:768437153
690 690 g, t dbSNP:749271182
702 702 a, g dbSNP:55948627
716 716 a, g dbSNP:780009103
722 722 a, g dbSNP:201319844
723 723 c, t dbSNP:571462337
729 729 a, c dbSNP:374210489
736 736 c, t dbSNP:557483957
742 742 g, t dbSNP:369872519
750 750 c, g dbSNP:752960891
775 775 c, g dbSNP:537695502
804 804 a, c, g, t dbSNP:369897902
805 805 a, g dbSNP:769780203
816 816 c, g dbSNP:745720934
836 836 a, g dbSNP:777973191
837 837 c, t dbSNP:758535737
844 844 a, g dbSNP:748433230
856 856 a, g dbSNP:374743161
858 858 c, t dbSNP:779248967
861 861 a, c, t dbSNP:138296278
867 867 c, g dbSNP:766595611
868 868 a, g dbSNP:756649872
878 878 a, g dbSNP:750891747
880 880 a, t dbSNP:767073502
884 884 c, g dbSNP:761281037
886 886 a, g dbSNP:145895692
898 898 c, g, t dbSNP:762455276
913 913 a, g dbSNP:569854672
917 917 a, c dbSNP:774577435
918 918 c, t dbSNP:768614635
922 922 c, g dbSNP:749583854
936 936 a, g dbSNP:780119090
937 937 c, g dbSNP:377504596
944 944 c, t dbSNP:746239398
954 954 c, t dbSNP:781477726
956 956 a, c, g dbSNP:375332869
960 960 c, t dbSNP:199596155
963 963 a, t dbSNP:757822064
965 965 a, t dbSNP:752436941
972 972 a, c dbSNP:764832916
973 973 g, t dbSNP:754614965
977 977 c, t dbSNP:370913967
978 978 a, g dbSNP:766211150
984 984 c, t dbSNP:377675152
987 987 a, c, t dbSNP:200547692
995 995 a, g dbSNP:762972992
997 997 g, t dbSNP:775590508
1000 1000 c, t dbSNP:769921604
1004 1004 a, g dbSNP:367812050
1018 1018 c, t dbSNP:137852653
1030 1030 a, c dbSNP:766335907
1050 1050 c, t dbSNP:188279224
1052 1052 c, t dbSNP:755952875
1057 1057 a, g dbSNP:750428025
1060 1060 g, t dbSNP:137852652
1067 1067 c, g dbSNP:571146259
1072 1072 g, t dbSNP:761751595
1076 1076 a, c dbSNP:775435999
1078 1078 c, t dbSNP:137852656
1080 1080 a, c dbSNP:199732560
1090 1090 c, t dbSNP:142274526
1091 1091 a, c, g dbSNP:771322282
1095 1095 c, t dbSNP:138804934
1101 1101 a, g dbSNP:773580745
1103 1103 a, g dbSNP:772474421
1108 1108 c, g dbSNP:748625870
1134 1134 c, t dbSNP:778354590
1135 1135 c, t dbSNP:754522846
1136 1136 a, g dbSNP:748999247
1138 1138 a, g dbSNP:779823081
1145 1145 c, t dbSNP:755776825
1146 1146 a, c, g dbSNP:780972997
1153 1153 a, g dbSNP:757207641
1154 1154 a, g dbSNP:751496694
1167 1167 c, g dbSNP:765277476
1172 1172 a, g dbSNP:762207370
1177 1177 c, t dbSNP:3179763
1178 1178 a, g, t dbSNP:144953891
1183 1183 c, t dbSNP:763485657
1188 1188 c, t dbSNP:775203006
1192 1192 -, aac dbSNP:397515510
1192 1192 a, g dbSNP:61739916
1199 1199 c, t dbSNP:745555403
1204 1204 a, g dbSNP:151050419
1221 1221 g, t dbSNP:770449845
1228 1228 a, g dbSNP:746841380
1234 1234 a, g dbSNP:200422116
1235 1235 g, t dbSNP:758338295
1236 1236 c, t dbSNP:201063220
1252 1252 a, g dbSNP:780165445
1253 1253 c, g dbSNP:756200063
1260 1260 c, t dbSNP:750654646
1262 1262 a, g dbSNP:767814536
1269 1269 c, g dbSNP:557014004
1282 1282 c, t dbSNP:751860122
1283 1283 a, c, t dbSNP:764546396
1284 1284 a, g dbSNP:368715216
1285 1285 a, g dbSNP:764590130
1288 1288 c, g dbSNP:764879634
1290 1290 g, t dbSNP:375908187
1293 1293 c, g dbSNP:776212021
1322 1322 c, t dbSNP:765804127
1349 1349 c, g dbSNP:774266370
1353 1353 c, t dbSNP:368273443
1360 1360 c, t dbSNP:762992681
1361 1361 a, g dbSNP:775255655
1367 1367 c, g, t dbSNP:747106682
1370 1370 c, g dbSNP:777939991
1383 1383 c, t dbSNP:543419638
1388 1388 g, t dbSNP:530668887
1391 1391 c, t dbSNP:779394384
1394 1394 a, g dbSNP:28936668
1411 1411 c, t dbSNP:755277222
1412 1412 c, t dbSNP:754409266
1420 1420 a, g dbSNP:375476152
1424 1424 c, g dbSNP:780461514
1435 1435 g, t dbSNP:756568697
1439 1439 a, g dbSNP:137852651
1440 1440 a, c dbSNP:375031149
1442 1442 a, t dbSNP:766950514
1443 1443 c, t dbSNP:761508334
1446 1446 c, t dbSNP:751147399
1447 1447 g, t dbSNP:28933699
1450 1450 g, t dbSNP:137852650
1453 1453 -, gac dbSNP:312262897
1454 1454 a, g dbSNP:28936669
1455 1455 -, gac dbSNP:312262898
1469 1469 a, c dbSNP:763986060
1477 1477 c, t dbSNP:762683869
1478 1478 a, g dbSNP:775306610
1482 1482 c, t dbSNP:769866414
1489 1489 c, g dbSNP:191645921
1499 1499 a, c dbSNP:773490189
1503 1503 c, t dbSNP:772268073
1505 1505 c, t dbSNP:748431274
1506 1506 a, c, g dbSNP:768883872
1507 1507 a, g dbSNP:541996591
1515 1515 -, gga dbSNP:770721341
1519 1519 a, g dbSNP:780411024
1520 1520 a, c, t dbSNP:373687591
1521 1521 a, g dbSNP:780728105
1522 1522 g, t dbSNP:756726447
1523 1523 a, g dbSNP:751036767
1524 1524 a, c dbSNP:143714206
1527 1527 a, c, g dbSNP:200037349
1530 1530 c, t dbSNP:763130585
1532 1532 g, t dbSNP:554998204
1533 1533 a, c dbSNP:769960335
1542 1542 c, t dbSNP:759913580
1554 1554 c, g, t dbSNP:149083265
1560 1560 a, t dbSNP:747544637
1563 1563 c, t dbSNP:777205423
1570 1570 a, c dbSNP:771590987
1571 1571 a, g dbSNP:747845826
1572 1572 a, g dbSNP:778740025
1584 1584 g, t dbSNP:535198633
1587 1587 c, t dbSNP:753703511
1591 1591 a, g dbSNP:779933113
1599 1599 a, g dbSNP:756075225
1604 1604 a, g dbSNP:750363391
1605 1605 c, g dbSNP:137852654
1615 1615 a, g dbSNP:312262902
1620 1620 c, g, t dbSNP:763122767
1622 1622 c, t dbSNP:312262903
1624 1624 a, g dbSNP:145034923
1625 1625 a, g dbSNP:765454754
1626 1626 a, c dbSNP:759687021
1633 1633 a, g dbSNP:777047473
1640 1640 a, g dbSNP:145283906
1643 1643 c, t dbSNP:377451339
1650 1650 c, g dbSNP:761133261
1653 1653 a, g dbSNP:773740227
1654 1654 g, t dbSNP:772420147
1655 1655 a, t dbSNP:747684271
1668 1668 a, c, g, t dbSNP:566112479
1669 1669 a, g dbSNP:779774621
1670 1670 c, t dbSNP:200870935
1675 1675 a, g dbSNP:750142844
1686 1686 c, g dbSNP:373498615
1692 1692 a, g dbSNP:757080842
1701 1701 a, c dbSNP:397515511
1709 1709 a, g dbSNP:762472383
1710 1710 a, g dbSNP:774980274
1713 1713 a, g dbSNP:764652826
1727 1727 c, t dbSNP:376678596
1732 1732 a, g dbSNP:774801993
1734 1734 a, c dbSNP:769488967
1738 1738 a, c dbSNP:577011338
1741 1741 a, g dbSNP:776545314
1742 1742 -, g dbSNP:751846896
1761 1761 g, t dbSNP:551897183
1767 1767 c, t dbSNP:772003134
1769 1769 -, a dbSNP:752882315
1770 1770 c, t dbSNP:61741109
1783 1783 a, g dbSNP:312262899
1790 1790 a, c, g, t dbSNP:312262900
1791 1791 a, g dbSNP:34467947
1796 1796 a, g dbSNP:312262901
1805 1805 c, t dbSNP:769742047
1806 1806 a, g dbSNP:547781183
1807 1807 a, g dbSNP:781599665
1812 1812 a, g dbSNP:757492278
1818 1818 c, t dbSNP:751974065
1824 1824 c, t dbSNP:778275855
1836 1836 c, t dbSNP:759000614
1839 1839 c, t dbSNP:753120962
1842 1842 c, t dbSNP:764842092
1849 1849 a, g dbSNP:397515512
1861 1861 c, t dbSNP:758999015
1865 1865 a, t dbSNP:753297721
1866 1866 c, t dbSNP:147854039
1880 1880 a, g dbSNP:760255360
1885 1885 a, c dbSNP:773059752
1886 1886 c, t dbSNP:771843783
1887 1887 a, g dbSNP:367665774
1895 1895 c, t dbSNP:761862151
1896 1896 a, g dbSNP:376703016
1906 1906 -, ggggg dbSNP:140413656
1907 1907 c, g, t dbSNP:201624503
1908 1908 -, g dbSNP:765246487
1908 1908 a, g dbSNP:200802161
1909 1909 a, g dbSNP:771344233
1910 1910 a, c, t dbSNP:778329355
1911 1911 a, c dbSNP:758658057
1915 1915 c, t dbSNP:748505181
1917 1917 c, t dbSNP:779309769
1929 1929 c, g dbSNP:755456322
1930 1930 a, g dbSNP:144170209
1934 1934 c, t dbSNP:202228058
1957 1957 a, g dbSNP:75729528
1960 1960 a, t dbSNP:749783671
1968 1968 a, g dbSNP:779591022
1969 1969 a, g dbSNP:755593138
1974 1974 c, t dbSNP:368459775
1975 1975 a, g dbSNP:757419000
1981 1981 c, g dbSNP:375484943
1983 1983 a, g dbSNP:371148267
1987 1987 c, t dbSNP:556356731
1989 1989 -, g dbSNP:35029628
1990 1990 a, g dbSNP:763030013
1992 1992 c, t dbSNP:10421797
1998 1998 a, g dbSNP:368444727
2006 2006 c, g dbSNP:565963328
2007 2007 a, g dbSNP:201439283
2014 2014 a, g dbSNP:376437040
2015 2015 -, ca dbSNP:760514744
2015 2015 c, g dbSNP:150534218
2017 2017 a, g dbSNP:372414886
2018 2018 -, ag dbSNP:767395029
2022 2022 c, t dbSNP:773284930
2024 2024 a, t dbSNP:141708238
2029 2029 c, t dbSNP:370202476
2030 2030 a, g dbSNP:774638335
2042 2042 a, c dbSNP:769045091
2043 2043 a, g dbSNP:749837889
2049 2049 g, t dbSNP:780573013
2050 2050 c, t dbSNP:148554460
2051 2051 a, g dbSNP:745399869
2056 2056 a, g dbSNP:780744328
2063 2063 a, g dbSNP:756913429
2072 2072 a, g dbSNP:751200102
2078 2078 c, g dbSNP:397515513
2081 2081 a, g dbSNP:777468425
2084 2084 a, c, g, t dbSNP:565459602
2101 2101 c, g dbSNP:765278469
2102 2102 a, g dbSNP:759480798
2117 2117 a, c dbSNP:146374758
2119 2119 a, g dbSNP:767622438
2126 2126 c, t dbSNP:764317174
2128 2128 c, g dbSNP:763098832
2129 2129 a, g dbSNP:569954000
2131 2131 g, t dbSNP:775886619
2139 2139 a, g dbSNP:770118419
2150 2150 c, t dbSNP:759998880
2157 2157 c, t dbSNP:142160846
2158 2158 a, g dbSNP:771292272
2166 2166 c, t dbSNP:556452100
2167 2167 a, g dbSNP:772781703
2169 2169 a, g dbSNP:139001378
2170 2170 c, g dbSNP:747790659
2182 2182 a, g dbSNP:778901691
2188 2188 a, c, t dbSNP:28936368
2189 2189 a, c, g dbSNP:149551600
2190 2190 g, t dbSNP:780066431
2191 2191 a, g dbSNP:312262904
2192 2192 a, g dbSNP:137852655
2197 2197 c, t dbSNP:755950559
2198 2198 a, g dbSNP:751668619
2199 2199 a, c dbSNP:747085396
2206 2206 a, g dbSNP:372951104
2215 2215 c, t dbSNP:374459827
2222 2222 a, g dbSNP:752882695
2240 2240 c, g dbSNP:765401313
2248 2248 c, g, t dbSNP:776802201
2249 2249 a, g dbSNP:766913050
2254 2254 c, t dbSNP:761081987
2255 2255 a, g dbSNP:138174876
2268 2268 a, c dbSNP:745619890
2271 2271 c, g, t dbSNP:755508135
2281 2281 c, t dbSNP:770795074
2288 2288 c, g dbSNP:201049035
2290 2290 c, t dbSNP:748229763
2292 2292 c, t dbSNP:778853514
2294 2294 a, t dbSNP:201893904
2298 2298 a, g dbSNP:150428337
2299 2299 c, t dbSNP:140511415
2300 2300 a, c, g dbSNP:756579573
2303 2303 a, g dbSNP:61752496
2307 2307 c, t dbSNP:768139579
2310 2310 a, g dbSNP:578142845
2311 2311 c, g dbSNP:77185131
2317 2317 a, g, t dbSNP:191758256
2318 2318 a, g dbSNP:762720044
2321 2321 a, g dbSNP:775030797
2325 2325 a, g dbSNP:201937857
2328 2328 c, t dbSNP:759333274
2329 2329 a, g dbSNP:376290752
2330 2330 a, c dbSNP:770913733
2331 2331 c, t dbSNP:746945906
2332 2332 a, c, g dbSNP:768596038
2338 2338 c, g dbSNP:749339585
2342 2342 c, t dbSNP:780168495
2350 2350 c, t dbSNP:374714490
2352 2352 a, g dbSNP:370642118
2353 2353 c, t dbSNP:781677628
2354 2354 a, g dbSNP:757901587
2355 2355 -, g dbSNP:761666626
2362 2362 g, t dbSNP:555498641
2387 2387 a, g dbSNP:536510231
2394 2394 a, g dbSNP:186977122
2402 2402 a, g dbSNP:9407
2414 2414 a, t dbSNP:533779545
2427 2427 a, g dbSNP:570994512

Target ORF information:

RefSeq Version NM_000095
Organism Homo sapiens (human)
Definition Homo sapiens cartilage oligomeric matrix protein (COMP), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000095

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGTCCCCG ACACCGCCTG CGTTCTTCTG CTCACCCTGG CTGCCCTCGG CGCGTCCGGA 
CAGGGCCAGA GCCCGTTGGG CTCAGACCTG GGCCCGCAGA TGCTTCGGGA ACTGCAGGAA
ACCAACGCGG CGCTGCAGGA CGTGCGGGAG CTGCTGCGGC AGCAGGTCAG GGAGATCACG
TTCCTGAAAA ACACGGTGAT GGAGTGTGAC GCGTGCGGGA TGCAGCAGTC AGTACGCACC
GGCCTACCCA GCGTGCGGCC CCTGCTCCAC TGCGCGCCCG GCTTCTGCTT CCCCGGCGTG
GCCTGCATCC AGACGGAGAG CGGCGCGCGC TGCGGCCCCT GCCCCGCGGG CTTCACGGGC
AACGGCTCGC ACTGCACCGA CGTCAACGAG TGCAACGCCC ACCCCTGCTT CCCCCGAGTC
CGCTGTATCA ACACCAGCCC GGGGTTCCGC TGCGAGGCTT GCCCGCCGGG GTACAGCGGC
CCCACCCACC AGGGCGTGGG GCTGGCTTTC GCCAAGGCCA ACAAGCAGGT TTGCACGGAC
ATCAACGAGT GTGAGACCGG GCAACATAAC TGCGTCCCCA ACTCCGTGTG CATCAACACC
CGGGGCTCCT TCCAGTGCGG CCCGTGCCAG CCCGGCTTCG TGGGCGACCA GGCGTCCGGC
TGCCAGCGGC GCGCACAGCG CTTCTGCCCC GACGGCTCGC CCAGCGAGTG CCACGAGCAT
GCAGACTGCG TCCTAGAGCG CGATGGCTCG CGGTCGTGCG TGTGTGCCGT TGGCTGGGCC
GGCAACGGGA TCCTCTGTGG TCGCGACACT GACCTAGACG GCTTCCCGGA CGAGAAGCTG
CGCTGCCCGG AGCGCCAGTG CCGTAAGGAC AACTGCGTGA CTGTGCCCAA CTCAGGGCAG
GAGGATGTGG ACCGCGATGG CATCGGAGAC GCCTGCGATC CGGATGCCGA CGGGGACGGG
GTCCCCAATG AAAAGGACAA CTGCCCGCTG GTGCGGAACC CAGACCAGCG CAACACGGAC
GAGGACAAGT GGGGCGATGC GTGCGACAAC TGCCGGTCCC AGAAGAACGA CGACCAAAAG
GACACAGACC AGGACGGCCG GGGCGATGCG TGCGACGACG ACATCGACGG CGACCGGATC
CGCAACCAGG CCGACAACTG CCCTAGGGTA CCCAACTCAG ACCAGAAGGA CAGTGATGGC
GATGGTATAG GGGATGCCTG TGACAACTGT CCCCAGAAGA GCAACCCGGA TCAGGCGGAT
GTGGACCACG ACTTTGTGGG AGATGCTTGT GACAGCGATC AAGACCAGGA TGGAGACGGA
CATCAGGACT CTCGGGACAA CTGTCCCACG GTGCCTAACA GTGCCCAGGA GGACTCAGAC
CACGATGGCC AGGGTGATGC CTGCGACGAC GACGACGACA ATGACGGAGT CCCTGACAGT
CGGGACAACT GCCGCCTGGT GCCTAACCCC GGCCAGGAGG ACGCGGACAG GGACGGCGTG
GGCGACGTGT GCCAGGACGA CTTTGATGCA GACAAGGTGG TAGACAAGAT CGACGTGTGT
CCGGAGAACG CTGAAGTCAC GCTCACCGAC TTCAGGGCCT TCCAGACAGT CGTGCTGGAC
CCGGAGGGTG ACGCGCAGAT TGACCCCAAC TGGGTGGTGC TCAACCAGGG AAGGGAGATC
GTGCAGACAA TGAACAGCGA CCCAGGCCTG GCTGTGGGTT ACACTGCCTT CAATGGCGTG
GACTTCGAGG GCACGTTCCA TGTGAACACG GTCACGGATG ACGACTATGC GGGCTTCATC
TTTGGCTACC AGGACAGCTC CAGCTTCTAC GTGGTCATGT GGAAGCAGAT GGAGCAAACG
TATTGGCAGG CGAACCCCTT CCGTGCTGTG GCCGAGCCTG GCATCCAACT CAAGGCTGTG
AAGTCTTCCA CAGGCCCCGG GGAACAGCTG CGGAACGCTC TGTGGCATAC AGGAGACACA
GAGTCCCAGG TGCGGCTGCT GTGGAAGGAC CCGCGAAACG TGGGTTGGAA GGACAAGAAG
TCCTATCGTT GGTTCCTGCA GCACCGGCCC CAAGTGGGCT ACATCAGGGT GCGATTCTAT
GAGGGCCCTG AGCTGGTGGC CGACAGCAAC GTGGTCTTGG ACACAACCAT GCGGGGTGGC
CGCCTGGGGG TCTTCTGCTT CTCCCAGGAG AACATCATCT GGGCCAACCT GCGTTACCGC
TGCAATGACA CCATCCCAGA GGACTATGAG ACCCATCAGC TGCGGCAAGC CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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