Email to GenScript

PRICKLE1 prickle homolog 1 [Homo sapiens (human)]

Gene Symbol PRICKLE1
Entrez Gene ID 144165
Full Name prickle homolog 1
Synonyms EPM1B, RILP
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q12

Summary This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]. lac of sum
Disorder MIM:

608500

Disorder Html: Epilepsy, progressive myoclonic 1B, 612437 (3)





The following PRICKLE1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRICKLE1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu22315 NM_001144881 Homo sapiens prickle homolog 1 (PRICKLE1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 Quote Price
OHu22315 NM_153026 Homo sapiens prickle homolog 1 (PRICKLE1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 Quote Price
OHu22315 NM_001144883 Homo sapiens prickle homolog 1 (PRICKLE1), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 Quote Price
OHu22315 NM_001144882 Homo sapiens prickle homolog 1 (PRICKLE1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu22315 XM_011537946 PREDICTED: Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 Quote Price
OHu22315 XM_011537947 PREDICTED: Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu22315
Accession Version NM_001144881.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2496bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 24-JUL-2015
Organism Homo sapiens (human)
Product prickle-like protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK122877.1, AC079601.25, BC114939.1 and BE858932.1. Summary: This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK122877.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGCCTTTGG AGATGGAGCC CAAGATGAGC AAACTGGCCT TTGGCTGTCA GAGAAGTTCC 
ACATCAGATG ATGACTCTGG CTGTGCATTG GAGGAGTACG CCTGGGTCCC CCCGGGCCTG
AGACCAGAGC AGATCCAGCT CTATTTTGCT TGCTTACCAG AGGAAAAAGT TCCTTACGTT
AACAGCCCCG GAGAGAAGCA TCGGATTAAA CAGCTTTTGT ACCAGTTACC ACCACATGAT
AATGAGGTAC GGTATTGCCA GTCTTTGAGT GAAGAGGAGA AAAAAGAGTT GCAGGTGTTC
AGTGCTCAGC GGAAGAAAGA AGCACTGGGA AGAGGAACAA TTAAGCTTCT GTCCAGAGCA
GTCATGCATG CTGTGTGTGA GCAGTGTGGT TTGAAGATAA ATGGAGGTGA AGTTGCAGTG
TTCGCCTCCC GTGCGGGCCC TGGTGTGTGC TGGCACCCAT CCTGTTTTGT CTGTTTCACG
TGTAATGAGC TGCTGGTCGA CCTCATCTAT TTTTATCAGG ATGGAAAAAT TCACTGTGGC
AGGCACCATG CAGAACTGCT CAAACCACGG TGCTCAGCAT GTGACGAGAT AATTTTTGCT
GATGAGTGCA CAGAAGCTGA GGGTCGCCAT TGGCACATGA AACACTTCTG CTGCCTTGAG
TGTGAAACGG TCCTGGGAGG ACAGAGGTAT ATCATGAAGG ACGGCCGCCC CTTCTGCTGT
GGCTGTTTTG AGTCTCTCTA TGCGGAGTAC TGTGAAACCT GTGGGGAACA TATTGGTGTG
GACCATGCAC AGATGACCTA TGACGGGCAG CACTGGCACG CCACGGAAGC CTGCTTTTCT
TGTGCCCAGT GTAAAGCCTC TTTGTTGGGA TGTCCCTTCC TTCCCAAACA GGGTCAGATT
TACTGCTCAA AAACGTGCAG TCTTGGTGAA GACGTCCATG CCTCTGATTC TTCCGACTCT
GCATTTCAGT CAGCTCGATC AAGAGACTCC CGAAGAAGTG TCCGAATGGG CAAGAGCAGC
CGGTCAGCAG ATCAGTGTAG ACAGTCTCTC CTCTTATCGC CTGCTCTGAA CTACAAGTTT
CCTGGCCTCT CAGGCAATGC TGATGACACC CTTTCTCGAA AATTGGATGA TCTGAGTCTC
TCCAGACAAG GAACAAGTTT TGCCAGTGAA GAATTTTGGA AAGGCAGAGT AGAGCAGGAA
ACTCCAGAAG ACCCTGAAGA ATGGGCTGAT CATGAAGATT ATATGACGCA GCTCCTCCTC
AAGTTTGGTG ATAAAAGCCT CTTTCAGCCA CAGCCCAATG AGATGGATAT TCGAGCCAGT
GAGCACTGGA TATCTGATAA CATGGTTAAA AGTAAGACCG AGTTAAAGCA AAATAACCAG
AGCCTTGCAA GTAAAAAATA CCAGTCTGAT ATGTACTGGG CACAGTCACA AGATGGACTG
GGCGATTCTG CTTATGGCAG CCACCCAGGC CCTGCAAGCA GTAGAAGGCT TCAGGAATTG
GAACTGGACC ATGGGGCTTC AGGGTATAAT CATGATGAAA CACAGTGGTA TGAAGATTCC
CTGGAGTGTC TGTCAGACCT GAAACCAGAG CAAAGTGTTC GGGATTCGAT GGATTCTTTG
GCATTGTCCA ATATCACAGG GGCTTCGGTG GATGGAGAAA ACAAGCCAAG GCCATCATTG
TATTCTCTGC AAAATTTTGA GGAGATGGAA ACAGAAGATT GTGAGAAGAT GAGCAATATG
GGAACTTTGA ACTCTTCCAT GCTGCACAGG AGTGCAGAGT CCTTAAAGAG TCTAAGTTCA
GAGTTGTGTC CAGAGAAAAT CCTGCCTGAA GAGAAGCCAG TACATCTGCC AGTGCTCAGA
AGGTCCAAGT CTCAATCCAG ACCCCAGCAG GTCAAGTTTT CTGATGATGT CATTGACAAT
GGGAACTATG ACATTGAAAT CCGGCAGCCT CCGATGAGTG AAAGGACTCG GAGACGCGTC
TACAATTTTG AAGAGAGGGG ATCCAGGTCT CATCACCACC GCCGCCGGAG AAGTAGAAAG
TCCCGCTCCG ACAATGCCCT GAATCTTGTT ACAGAAAGAA AATACTCTCC CAAGGACAGA
CTGCGGCTGT ACACCCCCGA TAACTATGAG AAATTTATAC AGAATAAAAG TGCCCGGGAG
ATCCAAGCAT ACATCCAGAA TGCTGATCTC TACGGACAGT ACGCCCATGC CACTTCCGAT
TATGGCCTGC AGAACCCAGG AATGAATCGG TTTCTGGGAC TCTACGGCGA GGATGATGAT
TCCTGGTGTT CTTCCTCCTC CTCCTCTTCC GACTCGGAAG AAGAAGGATA TTTTCTTGGA
CAACCAATCC CTCAACCCCG GCCACAGAGA TTTGCCTACT ATACAGATGA CCTTTCTAGT
CCACCATCTG CACTTCCCAC CCCTCAGTTT GGTCAGAGGA CAACAAAATC CAAGAAGAAA
AAGGGACACA AGGGCAAAAA TTGTATTATT TCTTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001138353.1
CDS288..2783
Misc Feature(1)261..263(+)
Misc Feature(2)351..641(+)
Misc Feature(3)663..839(+)
Misc Feature(4)663..833(+)
Misc Feature(5)852..1019(+)
Misc Feature(6)858..1013(+)
Misc Feature(7)1032..1208(+)
Misc Feature(8)1038..1205(+)
Misc Feature(9)2769..2771(+)
Exon (1)1..239
Gene:PRICKLE1
Gene Synonym:
Exon (2)240..419
Gene:PRICKLE1
Gene Synonym:
Exon (3)420..533
Gene:PRICKLE1
Gene Synonym:
Exon (4)534..671
Gene:PRICKLE1
Gene Synonym:
Exon (5)672..875
Gene:PRICKLE1
Gene Synonym:
Exon (6)876..1062
Gene:PRICKLE1
Gene Synonym:
Exon (7)1063..1926
Gene:PRICKLE1
Gene Synonym:
Exon (8)1927..4254
Gene:PRICKLE1
Gene Synonym:
Translation
Position Chain Variation Link
15 15 c, g dbSNP:564720562
19 19 a, g dbSNP:540261360
50 50 c, t dbSNP:1669919
84 84 c, t dbSNP:560995841
113 113 a, c dbSNP:542818682
154 154 a, g dbSNP:116954793
202 202 a, g dbSNP:111281694
222 222 c, g dbSNP:557253283
234 234 c, t dbSNP:544978986
246 246 c, t dbSNP:770613473
248 248 a, g dbSNP:370363439
255 255 a, g dbSNP:377567620
258 258 c, t dbSNP:755145462
260 260 a, g dbSNP:749324672
262 262 a, g dbSNP:780428375
266 266 a, g dbSNP:756354867
274 274 a, g dbSNP:200066556
275 275 c, g dbSNP:768032940
276 276 a, g dbSNP:373933563
277 277 a, c dbSNP:752163142
286 286 c, t dbSNP:186219547
295 295 -, t dbSNP:754532709
297 297 a, g dbSNP:762525821
299 299 a, g dbSNP:774935889
311 311 a, g dbSNP:764895665
312 312 a, g dbSNP:566073131
321 321 c, t dbSNP:752821879
324 324 a, g dbSNP:770828628
334 334 a, g dbSNP:746768839
335 335 c, t dbSNP:773216441
337 337 a, c dbSNP:771838146
347 347 a, c dbSNP:370960593
348 348 a, g dbSNP:780328472
386 386 c, t dbSNP:764986581
387 387 a, g, t dbSNP:781255236
388 388 c, t dbSNP:139176541
395 395 c, t dbSNP:147268650
400 400 -, c dbSNP:751319527
400 400 c, t dbSNP:145493619
401 401 a, g dbSNP:141743294
411 411 c, t dbSNP:758787019
412 412 c, t dbSNP:753183614
419 419 a, g dbSNP:377668062
428 428 c, g, t dbSNP:770054643
435 435 a, g dbSNP:745883137
438 438 c, t dbSNP:781477633
443 443 a, g dbSNP:771014475
448 448 a, g dbSNP:747418341
458 458 c, t dbSNP:778052349
461 461 g, t dbSNP:758734560
464 464 c, t dbSNP:144843013
468 468 a, g dbSNP:779382629
469 469 a, g dbSNP:754498750
470 470 c, t dbSNP:753221219
471 471 a, g dbSNP:140262447
475 475 c, t dbSNP:760293523
476 476 -, ccc dbSNP:779774332
476 476 c, t dbSNP:750059541
477 477 a, g dbSNP:767281272
487 487 a, g dbSNP:761685361
490 490 a, g dbSNP:774440655
493 493 c, t dbSNP:141795695
495 495 a, c dbSNP:759716073
530 530 -, t dbSNP:757924445
534 534 a, g dbSNP:764145941
536 536 a, g dbSNP:763029790
537 537 c, t dbSNP:775472022
538 538 a, g dbSNP:766439768
543 543 c, t dbSNP:112753281
565 565 a, g dbSNP:760798462
582 582 g, t dbSNP:773322867
597 597 c, t dbSNP:772217655
598 598 a, g dbSNP:113994140
605 605 a, g dbSNP:774649468
607 607 a, c dbSNP:201983132
609 609 a, g dbSNP:749826585
611 611 a, c dbSNP:143645243
632 632 a, g dbSNP:780596765
639 639 a, t dbSNP:755590703
648 648 c, g dbSNP:371720624
653 653 g, t dbSNP:745306550
657 657 a, g dbSNP:79087668
660 660 a, g dbSNP:756916881
661 661 c, t dbSNP:34837068
678 678 g, t dbSNP:35731866
686 686 a, c dbSNP:775864936
687 687 a, c dbSNP:200558941
693 693 a, c, g dbSNP:773739764
697 697 a, c dbSNP:533095698
709 709 g, t dbSNP:564918219
710 710 c, t dbSNP:746728526
713 713 c, t dbSNP:777559380
715 715 c, t dbSNP:758143303
718 718 a, g dbSNP:281865563
721 721 c, t dbSNP:765119777
722 722 a, g dbSNP:146650383
723 723 a, g dbSNP:753753811
724 724 g, t dbSNP:767649857
725 725 c, t dbSNP:761867849
732 732 a, g dbSNP:751791144
733 733 c, t dbSNP:528557291
734 734 a, g dbSNP:561240990
754 754 c, t dbSNP:775872848
756 756 a, g dbSNP:770028506
758 758 c, t dbSNP:201613485
766 766 c, t dbSNP:777277493
767 767 a, g dbSNP:376385820
777 777 c, g dbSNP:746462801
778 778 c, t dbSNP:777575981
796 796 a, g dbSNP:771717707
804 804 c, g dbSNP:747920863
808 808 a, g dbSNP:778817395
826 826 g, t dbSNP:754699794
836 836 c, t dbSNP:753829444
837 837 a, g dbSNP:765876974
840 840 g, t dbSNP:61924369
842 842 a, g dbSNP:779908231
845 845 g, t dbSNP:199650711
853 853 c, t dbSNP:751596896
860 860 c, t dbSNP:764241108
863 863 a, c dbSNP:763282675
866 866 a, c dbSNP:752826795
872 872 c, t dbSNP:74081707
873 873 a, g dbSNP:759969939
877 877 c, t dbSNP:542029566
899 899 a, c dbSNP:755994241
912 912 a, c, t dbSNP:777944504
913 913 a, g dbSNP:758400992
923 923 c, t dbSNP:753025298
924 924 a, c dbSNP:765322400
936 936 c, t dbSNP:772276749
945 945 a, g dbSNP:200263143
955 955 c, t dbSNP:754218148
956 956 a, g dbSNP:201394996
974 974 a, g dbSNP:761315405
976 976 a, g dbSNP:773561952
990 990 a, g dbSNP:375197568
993 993 c, t dbSNP:372213429
1001 1001 c, t dbSNP:368850875
1005 1005 c, t dbSNP:774058029
1007 1007 c, t dbSNP:374695088
1012 1012 -, g, gg dbSNP:148197048
1013 1013 g, t dbSNP:74918611
1017 1017 g, t dbSNP:775310173
1018 1018 a, t dbSNP:769543803
1023 1023 a, c dbSNP:745880716
1026 1026 c, t dbSNP:780974681
1031 1031 a, g dbSNP:34778200
1037 1037 c, t dbSNP:748113916
1045 1045 a, c dbSNP:779229187
1057 1057 a, g dbSNP:755578011
1074 1074 a, g dbSNP:775135171
1091 1091 c, t dbSNP:371149992
1092 1092 a, g dbSNP:376845777
1094 1094 a, g dbSNP:757752736
1095 1095 a, c dbSNP:752070986
1106 1106 c, t dbSNP:763656364
1107 1107 a, g dbSNP:762434475
1111 1111 c, t dbSNP:559947948
1112 1112 a, g dbSNP:368347802
1137 1137 c, t dbSNP:764805797
1141 1141 a, g dbSNP:759409673
1148 1148 c, t dbSNP:537302175
1163 1163 c, g dbSNP:776244004
1173 1173 a, g dbSNP:770740860
1193 1193 c, t dbSNP:759688762
1197 1197 a, g dbSNP:202205425
1201 1201 c, t dbSNP:375459191
1202 1202 a, g, t dbSNP:150052192
1204 1204 a, g dbSNP:768917442
1214 1214 g, t dbSNP:529793741
1221 1221 a, g dbSNP:780452958
1231 1231 c, g dbSNP:769860194
1241 1241 c, g, t dbSNP:139421676
1260 1260 c, g dbSNP:757632765
1264 1264 a, g dbSNP:752116352
1279 1279 a, g dbSNP:778192552
1291 1291 a, g dbSNP:757911190
1294 1294 c, g, t dbSNP:76029235
1303 1303 a, g dbSNP:764895755
1308 1308 c, t dbSNP:759164554
1309 1309 a, g dbSNP:577174749
1310 1310 a, c, g dbSNP:370013528
1311 1311 g, t dbSNP:773297758
1323 1323 c, t dbSNP:772094351
1337 1337 c, t dbSNP:141763288
1344 1344 c, t dbSNP:775761309
1346 1346 a, g dbSNP:769884613
1367 1367 c, t dbSNP:746139680
1373 1373 c, t dbSNP:781459043
1384 1384 a, g dbSNP:771210638
1390 1390 a, g dbSNP:747305137
1396 1396 a, c dbSNP:778286825
1422 1422 a, t dbSNP:758856895
1432 1432 a, g dbSNP:748636455
1433 1433 a, c dbSNP:778330311
1436 1436 a, g dbSNP:375407377
1443 1443 a, t dbSNP:754507423
1463 1463 c, t dbSNP:571386763
1489 1489 c, t dbSNP:766000495
1492 1492 c, t dbSNP:755979431
1495 1495 a, g dbSNP:367941464
1509 1509 c, g, t dbSNP:376384105
1512 1512 a, g dbSNP:774422189
1521 1521 a, g dbSNP:765287368
1525 1525 a, t dbSNP:759600108
1530 1530 a, g dbSNP:776720321
1534 1534 c, t dbSNP:151332996
1535 1535 a, g dbSNP:142502371
1554 1554 g, t dbSNP:773620209
1555 1555 a, g dbSNP:371689139
1566 1566 c, t dbSNP:553919252
1568 1568 c, t dbSNP:748722157
1569 1569 c, t dbSNP:779462876
1571 1571 c, t dbSNP:183742526
1585 1585 a, g dbSNP:748766846
1586 1586 a, t dbSNP:779594296
1596 1596 a, t dbSNP:755877569
1599 1599 c, g dbSNP:750068527
1614 1614 c, t dbSNP:767486612
1617 1617 a, c dbSNP:146199468
1620 1620 a, t dbSNP:751460514
1623 1623 c, g dbSNP:764022861
1628 1628 c, t dbSNP:759563559
1629 1629 a, t dbSNP:776727562
1632 1632 g, t dbSNP:766349772
1643 1643 a, g dbSNP:760931731
1645 1645 a, c dbSNP:773422113
1646 1646 c, g dbSNP:772484365
1647 1647 a, g dbSNP:748454609
1651 1651 c, t dbSNP:774727935
1659 1659 a, g dbSNP:769168031
1664 1664 c, t dbSNP:749735572
1673 1673 c, t dbSNP:779653619
1677 1677 a, c dbSNP:769424445
1678 1678 a, g dbSNP:138568653
1680 1680 a, g dbSNP:780931107
1690 1690 a, g dbSNP:556311726
1693 1693 c, g dbSNP:751326939
1699 1699 c, t dbSNP:777597253
1701 1701 c, t dbSNP:281865564
1704 1704 a, t dbSNP:538066196
1722 1722 a, g dbSNP:570770626
1725 1725 c, g dbSNP:552840971
1727 1727 c, g dbSNP:367822804
1730 1730 c, t dbSNP:376123082
1736 1736 c, t dbSNP:760731193
1748 1748 c, t dbSNP:116197349
1764 1764 a, c dbSNP:547914367
1768 1768 c, g dbSNP:560995986
1773 1773 a, c dbSNP:371789655
1775 1775 c, g dbSNP:762118167
1784 1784 a, g dbSNP:774825872
1792 1792 g, t dbSNP:768870075
1793 1793 a, g dbSNP:200460878
1798 1798 a, g dbSNP:201054946
1799 1799 c, t dbSNP:769438599
1804 1804 c, t dbSNP:745306755
1807 1807 c, t dbSNP:781019264
1828 1828 c, t dbSNP:374333566
1834 1834 c, g dbSNP:139901494
1846 1846 c, g dbSNP:777667268
1850 1850 a, g dbSNP:758126980
1854 1854 c, t dbSNP:150121787
1882 1882 a, g dbSNP:778765052
1888 1888 a, g dbSNP:756192425
1889 1889 a, g dbSNP:750464270
1890 1890 c, g dbSNP:371146879
1894 1894 c, t dbSNP:150766064
1895 1895 a, g dbSNP:144062651
1899 1899 g, t dbSNP:751724595
1900 1900 a, c dbSNP:764577468
1908 1908 g, t dbSNP:763169354
1910 1910 a, t dbSNP:776141626
1916 1916 a, c, t dbSNP:748556304
1919 1919 c, t dbSNP:776332277
1928 1928 a, g dbSNP:533432460
1933 1933 c, t dbSNP:370892022
1934 1934 a, c, g dbSNP:149518219
1935 1935 a, g dbSNP:760050261
1943 1943 a, t dbSNP:772922391
1963 1963 c, t dbSNP:771584708
1982 1982 g, t dbSNP:747960166
1998 1998 a, g dbSNP:774182139
1999 1999 c, t dbSNP:192905881
2034 2034 c, t dbSNP:138079613
2042 2042 c, t dbSNP:749279543
2055 2055 a, c, g dbSNP:757362404
2056 2056 a, g dbSNP:747016163
2059 2059 c, g dbSNP:778075325
2068 2068 a, c dbSNP:758594837
2073 2073 a, g dbSNP:752938677
2078 2078 g, t dbSNP:765766362
2080 2080 -, t dbSNP:776696757
2091 2091 g, t dbSNP:368664984
2104 2104 a, c dbSNP:754414301
2106 2106 a, t dbSNP:766728682
2120 2120 a, c, g dbSNP:749854195
2132 2132 a, t dbSNP:767033548
2143 2143 c, t dbSNP:761518408
2151 2151 c, t dbSNP:773978081
2152 2152 a, c dbSNP:768451748
2154 2154 a, g dbSNP:762668703
2156 2156 a, c, g dbSNP:150809651
2166 2166 a, c dbSNP:745792839
2175 2175 c, g dbSNP:200171609
2184 2184 -, tt dbSNP:111643910
2186 2186 c, t dbSNP:3747563
2189 2189 -, cc dbSNP:112291115
2189 2189 c, t dbSNP:3747562
2206 2206 a, g dbSNP:139937830
2209 2209 a, c, g dbSNP:374621616
2219 2219 c, t dbSNP:754215976
2220 2220 a, g dbSNP:780633961
2229 2229 c, g dbSNP:370129051
2239 2239 c, t dbSNP:750913400
2240 2240 c, g dbSNP:766992928
2250 2250 a, g dbSNP:557639324
2256 2256 c, g dbSNP:751217827
2262 2262 c, t dbSNP:376257338
2265 2265 a, g dbSNP:143947284
2269 2269 a, c dbSNP:775196409
2272 2272 a, g dbSNP:769599129
2273 2273 c, t dbSNP:759461345
2279 2279 a, g dbSNP:373302710
2284 2284 a, g dbSNP:370547490
2289 2289 a, t dbSNP:794727934
2298 2298 c, t dbSNP:776619006
2307 2307 c, t dbSNP:572205675
2308 2308 c, g dbSNP:748173327
2313 2313 c, t dbSNP:779314205
2314 2314 a, g dbSNP:377294908
2331 2331 c, t dbSNP:768954477
2332 2332 a, g dbSNP:189093086
2351 2351 c, t dbSNP:199893979
2358 2358 a, g dbSNP:149496604
2368 2368 a, g dbSNP:750904030
2376 2376 c, t dbSNP:781672373
2378 2378 c, t dbSNP:756787066
2391 2391 c, t dbSNP:751021008
2392 2392 a, g dbSNP:369790443
2395 2395 c, t dbSNP:758085094
2398 2398 a, t dbSNP:752387857
2401 2401 a, c dbSNP:765001355
2403 2403 c, t dbSNP:377228096
2405 2405 c, t dbSNP:374657704
2406 2406 a, g dbSNP:369077719
2409 2409 a, g dbSNP:371991440
2413 2413 a, g dbSNP:750226436
2415 2415 a, g dbSNP:774624657
2431 2431 a, g dbSNP:768827796
2432 2432 a, t dbSNP:749541698
2434 2434 a, g dbSNP:775721420
2441 2441 a, c dbSNP:770055515
2442 2442 c, t dbSNP:746199700
2443 2443 a, g dbSNP:779059953
2445 2445 a, g dbSNP:757810750
2456 2456 a, t dbSNP:757496174
2458 2458 a, t dbSNP:747481880
2476 2476 a, t dbSNP:777329767
2479 2479 a, g dbSNP:567656128
2480 2480 c, t dbSNP:137985321
2481 2481 a, g dbSNP:150287042
2489 2489 c, t dbSNP:570186739
2496 2496 a, g dbSNP:753625155
2503 2503 c, t dbSNP:138452760
2505 2505 g, t dbSNP:760738396
2509 2509 a, g dbSNP:375420597
2511 2511 a, g dbSNP:370967125
2523 2523 c, t dbSNP:3827522
2537 2537 a, g dbSNP:775601706
2549 2549 c, g dbSNP:727504104
2551 2551 -, ta dbSNP:768660106
2552 2552 c, t dbSNP:148989635
2553 2553 a, g dbSNP:777019107
2555 2555 c, t dbSNP:771279388
2556 2556 a, g dbSNP:145860632
2563 2563 a, g dbSNP:778196919
2565 2565 -, gat dbSNP:557205452
2570 2570 c, t dbSNP:149852787
2581 2581 c, t dbSNP:747655113
2588 2588 c, t dbSNP:778452934
2591 2591 -, ctc dbSNP:779393661
2591 2591 c, g dbSNP:35854729
2597 2597 c, t dbSNP:529575327
2598 2598 g, t dbSNP:146670726
2600 2600 c, t dbSNP:755963146
2603 2603 a, g dbSNP:143240342
2611 2611 -, aag dbSNP:758094682
2617 2617 a, g dbSNP:768039518
2623 2623 c, t dbSNP:374409698
2631 2631 c, t dbSNP:752866274
2646 2646 c, t dbSNP:765199745
2647 2647 a, g, t dbSNP:776819993
2650 2650 c, t dbSNP:200984524
2651 2651 a, g dbSNP:760964320
2654 2654 a, g dbSNP:549385436
2657 2657 a, g dbSNP:375310663
2667 2667 c, t dbSNP:201705679
2669 2669 c, t dbSNP:538043977
2672 2672 a, g dbSNP:748585713
2675 2675 c, t dbSNP:778528977
2676 2676 c, g dbSNP:746765797
2684 2684 c, t dbSNP:768050274
2687 2687 a, t dbSNP:139855191
2688 2688 c, t dbSNP:779783898
2691 2691 c, t dbSNP:150545495
2693 2693 a, g dbSNP:377290931
2699 2699 a, c dbSNP:750190848
2709 2709 a, c dbSNP:780823369
2712 2712 c, g dbSNP:142613488
2718 2718 a, g dbSNP:751446088
2721 2721 -, cagaggaca dbSNP:745483751
2726 2726 a, g dbSNP:138524511
2744 2744 a, g dbSNP:759552132
2749 2749 a, g dbSNP:754065513
2756 2756 c, t dbSNP:766549997
2774 2774 c, t dbSNP:376858650
2785 2785 c, t dbSNP:555008439
2786 2786 a, g dbSNP:567492165
2818 2818 a, g dbSNP:200644857
2828 2828 c, g, t dbSNP:372633476
2829 2829 a, g, t dbSNP:147122337
2838 2838 a, g dbSNP:560130870
2853 2853 a, g dbSNP:759888600
2858 2858 a, g dbSNP:542130236
2874 2874 c, t dbSNP:1043652
2886 2886 -, t dbSNP:151151770
2912 2912 a, g dbSNP:572315226
2992 2992 a, g dbSNP:192612214
3001 3001 c, t dbSNP:537460102
3011 3011 c, t dbSNP:576421272
3035 3035 a, c dbSNP:558237556
3044 3044 c, t dbSNP:1043656
3078 3078 -, at dbSNP:558821449
3078 3078 c, t dbSNP:761391791
3118 3118 a, g dbSNP:570071895
3149 3149 a, g dbSNP:547699182
3173 3173 c, g dbSNP:768200105
3181 3181 g, t dbSNP:17091220
3185 3185 g, t dbSNP:568438224
3190 3190 a, g, t dbSNP:745482621
3193 3193 c, t dbSNP:781107806
3213 3213 c, g dbSNP:141738298
3219 3219 c, g dbSNP:746977003
3220 3220 a, g dbSNP:777503447
3224 3224 a, c dbSNP:755082741
3231 3231 a, t dbSNP:571674666
3266 3266 a, c dbSNP:187632148
3275 3275 c, g dbSNP:563966550
3300 3300 c, t dbSNP:766425066
3310 3310 g, t dbSNP:12658
3311 3311 c, t dbSNP:750610528
3316 3316 c, t dbSNP:527422458
3325 3325 -, aa dbSNP:76259006
3325 3325 -, a dbSNP:398019285
3329 3329 a, c dbSNP:767986403
3334 3334 -, aa dbSNP:778238511
3335 3335 -, a dbSNP:756462439
3335 3335 -, a dbSNP:68074167
3335 3335 a, c dbSNP:778702730
3348 3348 c, t dbSNP:762030087
3376 3376 g, t dbSNP:757584408
3377 3377 -, aa dbSNP:769616581
3396 3396 c, t dbSNP:775224782
3464 3464 -, t dbSNP:567650778
3480 3480 c, t dbSNP:749474350
3498 3498 g, t dbSNP:147942021
3585 3585 a, g dbSNP:778118882
3619 3619 -, t dbSNP:746752965
3642 3642 a, g dbSNP:756303597
3680 3680 a, g dbSNP:368596743
3683 3683 c, t dbSNP:542060460
3697 3697 a, c dbSNP:551815384
3709 3709 c, t dbSNP:574754036
3715 3715 a, t dbSNP:555892431
3727 3727 c, t dbSNP:749282719
3732 3732 a, t dbSNP:752821017
3766 3766 a, c dbSNP:73126459
3795 3795 a, g dbSNP:537803462
3806 3806 a, g dbSNP:756229345
3818 3818 -, t dbSNP:759701217
3818 3818 -, t dbSNP:201368761
3827 3827 c, t dbSNP:543795157
3829 3829 c, g dbSNP:533279850
3830 3830 c, t dbSNP:11181513
3854 3854 a, g dbSNP:182902189
3862 3862 a, c dbSNP:751878241
3894 3894 c, t dbSNP:557897526
3953 3953 c, t dbSNP:192161217
3965 3965 c, t dbSNP:572465188
4057 4057 -, ttgagtactgtaagt dbSNP:376939377
4058 4058 -, tgagtactgtaagtt dbSNP:572638131
4066 4066 g, t dbSNP:1669933
4148 4148 c, t dbSNP:535656837
4151 4151 c, t dbSNP:568374912
4177 4177 a, g dbSNP:1051453
4233 4233 a, c dbSNP:3168685

Target ORF information:

RefSeq Version NM_001144881
Organism Homo sapiens (human)
Definition Homo sapiens prickle homolog 1 (PRICKLE1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001144881

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGCCTTTGG AGATGGAGCC CAAGATGAGC AAACTGGCCT TTGGCTGTCA GAGAAGTTCC 
ACATCAGATG ATGACTCTGG CTGTGCATTG GAGGAGTACG CCTGGGTCCC CCCGGGCCTG
AGACCAGAGC AGATCCAGCT CTATTTTGCT TGCTTACCAG AGGAAAAAGT TCCTTACGTT
AACAGCCCCG GAGAGAAGCA TCGGATTAAA CAGCTTTTGT ACCAGTTACC ACCACATGAT
AATGAGGTAC GGTATTGCCA GTCTTTGAGT GAAGAGGAGA AAAAAGAGTT GCAGGTGTTC
AGTGCTCAGC GGAAGAAAGA AGCACTGGGA AGAGGAACAA TTAAGCTTCT GTCCAGAGCA
GTCATGCATG CTGTGTGTGA GCAGTGTGGT TTGAAGATAA ATGGAGGTGA AGTTGCAGTG
TTCGCCTCCC GTGCGGGCCC TGGTGTGTGC TGGCACCCAT CCTGTTTTGT CTGTTTCACG
TGTAATGAGC TGCTGGTCGA CCTCATCTAT TTTTATCAGG ATGGAAAAAT TCACTGTGGC
AGGCACCATG CAGAACTGCT CAAACCACGG TGCTCAGCAT GTGACGAGAT AATTTTTGCT
GATGAGTGCA CAGAAGCTGA GGGTCGCCAT TGGCACATGA AACACTTCTG CTGCCTTGAG
TGTGAAACGG TCCTGGGAGG ACAGAGGTAT ATCATGAAGG ACGGCCGCCC CTTCTGCTGT
GGCTGTTTTG AGTCTCTCTA TGCGGAGTAC TGTGAAACCT GTGGGGAACA TATTGGTGTG
GACCATGCAC AGATGACCTA TGACGGGCAG CACTGGCACG CCACGGAAGC CTGCTTTTCT
TGTGCCCAGT GTAAAGCCTC TTTGTTGGGA TGTCCCTTCC TTCCCAAACA GGGTCAGATT
TACTGCTCAA AAACGTGCAG TCTTGGTGAA GACGTCCATG CCTCTGATTC TTCCGACTCT
GCATTTCAGT CAGCTCGATC AAGAGACTCC CGAAGAAGTG TCCGAATGGG CAAGAGCAGC
CGGTCAGCAG ATCAGTGTAG ACAGTCTCTC CTCTTATCGC CTGCTCTGAA CTACAAGTTT
CCTGGCCTCT CAGGCAATGC TGATGACACC CTTTCTCGAA AATTGGATGA TCTGAGTCTC
TCCAGACAAG GAACAAGTTT TGCCAGTGAA GAATTTTGGA AAGGCAGAGT AGAGCAGGAA
ACTCCAGAAG ACCCTGAAGA ATGGGCTGAT CATGAAGATT ATATGACGCA GCTCCTCCTC
AAGTTTGGTG ATAAAAGCCT CTTTCAGCCA CAGCCCAATG AGATGGATAT TCGAGCCAGT
GAGCACTGGA TATCTGATAA CATGGTTAAA AGTAAGACCG AGTTAAAGCA AAATAACCAG
AGCCTTGCAA GTAAAAAATA CCAGTCTGAT ATGTACTGGG CACAGTCACA AGATGGACTG
GGCGATTCTG CTTATGGCAG CCACCCAGGC CCTGCAAGCA GTAGAAGGCT TCAGGAATTG
GAACTGGACC ATGGGGCTTC AGGGTATAAT CATGATGAAA CACAGTGGTA TGAAGATTCC
CTGGAGTGTC TGTCAGACCT GAAACCAGAG CAAAGTGTTC GGGATTCGAT GGATTCTTTG
GCATTGTCCA ATATCACAGG GGCTTCGGTG GATGGAGAAA ACAAGCCAAG GCCATCATTG
TATTCTCTGC AAAATTTTGA GGAGATGGAA ACAGAAGATT GTGAGAAGAT GAGCAATATG
GGAACTTTGA ACTCTTCCAT GCTGCACAGG AGTGCAGAGT CCTTAAAGAG TCTAAGTTCA
GAGTTGTGTC CAGAGAAAAT CCTGCCTGAA GAGAAGCCAG TACATCTGCC AGTGCTCAGA
AGGTCCAAGT CTCAATCCAG ACCCCAGCAG GTCAAGTTTT CTGATGATGT CATTGACAAT
GGGAACTATG ACATTGAAAT CCGGCAGCCT CCGATGAGTG AAAGGACTCG GAGACGCGTC
TACAATTTTG AAGAGAGGGG ATCCAGGTCT CATCACCACC GCCGCCGGAG AAGTAGAAAG
TCCCGCTCCG ACAATGCCCT GAATCTTGTT ACAGAAAGAA AATACTCTCC CAAGGACAGA
CTGCGGCTGT ACACCCCCGA TAACTATGAG AAATTTATAC AGAATAAAAG TGCCCGGGAG
ATCCAAGCAT ACATCCAGAA TGCTGATCTC TACGGACAGT ACGCCCATGC CACTTCCGAT
TATGGCCTGC AGAACCCAGG AATGAATCGG TTTCTGGGAC TCTACGGCGA GGATGATGAT
TCCTGGTGTT CTTCCTCCTC CTCCTCTTCC GACTCGGAAG AAGAAGGATA TTTTCTTGGA
CAACCAATCC CTCAACCCCG GCCACAGAGA TTTGCCTACT ATACAGATGA CCTTTCTAGT
CCACCATCTG CACTTCCCAC CCCTCAGTTT GGTCAGAGGA CAACAAAATC CAAGAAGAAA
AAGGGACACA AGGGCAAAAA TTGTATTATT TCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22315
Accession Version NM_153026.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2496bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 24-JUL-2015
Organism Homo sapiens (human)
Product prickle-like protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA413584.1, BC114939.1, AC079601.25 and BE858932.1. This sequence is a reference standard in the RefSeqGene project. On or before Jan 30, 2009 this sequence version replaced gi:169204134, gi:169204694, gi:23308518. Summary: This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]. Transcript Variant: This variant (1) represents the longest transcript. Variants 1-4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF399844.1, AK056499.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGCCTTTGG AGATGGAGCC CAAGATGAGC AAACTGGCCT TTGGCTGTCA GAGAAGTTCC 
ACATCAGATG ATGACTCTGG CTGTGCATTG GAGGAGTACG CCTGGGTCCC CCCGGGCCTG
AGACCAGAGC AGATCCAGCT CTATTTTGCT TGCTTACCAG AGGAAAAAGT TCCTTACGTT
AACAGCCCCG GAGAGAAGCA TCGGATTAAA CAGCTTTTGT ACCAGTTACC ACCACATGAT
AATGAGGTAC GGTATTGCCA GTCTTTGAGT GAAGAGGAGA AAAAAGAGTT GCAGGTGTTC
AGTGCTCAGC GGAAGAAAGA AGCACTGGGA AGAGGAACAA TTAAGCTTCT GTCCAGAGCA
GTCATGCATG CTGTGTGTGA GCAGTGTGGT TTGAAGATAA ATGGAGGTGA AGTTGCAGTG
TTCGCCTCCC GTGCGGGCCC TGGTGTGTGC TGGCACCCAT CCTGTTTTGT CTGTTTCACG
TGTAATGAGC TGCTGGTCGA CCTCATCTAT TTTTATCAGG ATGGAAAAAT TCACTGTGGC
AGGCACCATG CAGAACTGCT CAAACCACGG TGCTCAGCAT GTGACGAGAT AATTTTTGCT
GATGAGTGCA CAGAAGCTGA GGGTCGCCAT TGGCACATGA AACACTTCTG CTGCCTTGAG
TGTGAAACGG TCCTGGGAGG ACAGAGGTAT ATCATGAAGG ACGGCCGCCC CTTCTGCTGT
GGCTGTTTTG AGTCTCTCTA TGCGGAGTAC TGTGAAACCT GTGGGGAACA TATTGGTGTG
GACCATGCAC AGATGACCTA TGACGGGCAG CACTGGCACG CCACGGAAGC CTGCTTTTCT
TGTGCCCAGT GTAAAGCCTC TTTGTTGGGA TGTCCCTTCC TTCCCAAACA GGGTCAGATT
TACTGCTCAA AAACGTGCAG TCTTGGTGAA GACGTCCATG CCTCTGATTC TTCCGACTCT
GCATTTCAGT CAGCTCGATC AAGAGACTCC CGAAGAAGTG TCCGAATGGG CAAGAGCAGC
CGGTCAGCAG ATCAGTGTAG ACAGTCTCTC CTCTTATCGC CTGCTCTGAA CTACAAGTTT
CCTGGCCTCT CAGGCAATGC TGATGACACC CTTTCTCGAA AATTGGATGA TCTGAGTCTC
TCCAGACAAG GAACAAGTTT TGCCAGTGAA GAATTTTGGA AAGGCAGAGT AGAGCAGGAA
ACTCCAGAAG ACCCTGAAGA ATGGGCTGAT CATGAAGATT ATATGACGCA GCTCCTCCTC
AAGTTTGGTG ATAAAAGCCT CTTTCAGCCA CAGCCCAATG AGATGGATAT TCGAGCCAGT
GAGCACTGGA TATCTGATAA CATGGTTAAA AGTAAGACCG AGTTAAAGCA AAATAACCAG
AGCCTTGCAA GTAAAAAATA CCAGTCTGAT ATGTACTGGG CACAGTCACA AGATGGACTG
GGCGATTCTG CTTATGGCAG CCACCCAGGC CCTGCAAGCA GTAGAAGGCT TCAGGAATTG
GAACTGGACC ATGGGGCTTC AGGGTATAAT CATGATGAAA CACAGTGGTA TGAAGATTCC
CTGGAGTGTC TGTCAGACCT GAAACCAGAG CAAAGTGTTC GGGATTCGAT GGATTCTTTG
GCATTGTCCA ATATCACAGG GGCTTCGGTG GATGGAGAAA ACAAGCCAAG GCCATCATTG
TATTCTCTGC AAAATTTTGA GGAGATGGAA ACAGAAGATT GTGAGAAGAT GAGCAATATG
GGAACTTTGA ACTCTTCCAT GCTGCACAGG AGTGCAGAGT CCTTAAAGAG TCTAAGTTCA
GAGTTGTGTC CAGAGAAAAT CCTGCCTGAA GAGAAGCCAG TACATCTGCC AGTGCTCAGA
AGGTCCAAGT CTCAATCCAG ACCCCAGCAG GTCAAGTTTT CTGATGATGT CATTGACAAT
GGGAACTATG ACATTGAAAT CCGGCAGCCT CCGATGAGTG AAAGGACTCG GAGACGCGTC
TACAATTTTG AAGAGAGGGG ATCCAGGTCT CATCACCACC GCCGCCGGAG AAGTAGAAAG
TCCCGCTCCG ACAATGCCCT GAATCTTGTT ACAGAAAGAA AATACTCTCC CAAGGACAGA
CTGCGGCTGT ACACCCCCGA TAACTATGAG AAATTTATAC AGAATAAAAG TGCCCGGGAG
ATCCAAGCAT ACATCCAGAA TGCTGATCTC TACGGACAGT ACGCCCATGC CACTTCCGAT
TATGGCCTGC AGAACCCAGG AATGAATCGG TTTCTGGGAC TCTACGGCGA GGATGATGAT
TCCTGGTGTT CTTCCTCCTC CTCCTCTTCC GACTCGGAAG AAGAAGGATA TTTTCTTGGA
CAACCAATCC CTCAACCCCG GCCACAGAGA TTTGCCTACT ATACAGATGA CCTTTCTAGT
CCACCATCTG CACTTCCCAC CCCTCAGTTT GGTCAGAGGA CAACAAAATC CAAGAAGAAA
AAGGGACACA AGGGCAAAAA TTGTATTATT TCTTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_694571.2
CDS355..2850
Misc Feature(1)328..330(+)
Misc Feature(2)418..708(+)
Misc Feature(3)730..906(+)
Misc Feature(4)730..900(+)
Misc Feature(5)919..1086(+)
Misc Feature(6)925..1080(+)
Misc Feature(7)1099..1275(+)
Misc Feature(8)1105..1272(+)
Misc Feature(9)2836..2838(+)
Exon (1)1..306
Gene:PRICKLE1
Gene Synonym:
Exon (2)307..486
Gene:PRICKLE1
Gene Synonym:
Exon (3)487..600
Gene:PRICKLE1
Gene Synonym:
Exon (4)601..738
Gene:PRICKLE1
Gene Synonym:
Exon (5)739..942
Gene:PRICKLE1
Gene Synonym:
Exon (6)943..1129
Gene:PRICKLE1
Gene Synonym:
Exon (7)1130..1993
Gene:PRICKLE1
Gene Synonym:
Exon (8)1994..4321
Gene:PRICKLE1
Gene Synonym:
Translation
Position Chain Variation Link
31 31 a, c dbSNP:561895960
106 106 c, t dbSNP:543617300
139 139 c, t dbSNP:576131579
142 142 c, g dbSNP:557557453
151 151 a, g dbSNP:548377394
165 165 c, g dbSNP:145508056
174 174 a, g dbSNP:117521428
232 232 c, t dbSNP:545930952
248 248 -, cgcagccc dbSNP:561368128
249 249 a, c dbSNP:535764464
313 313 c, t dbSNP:770613473
315 315 a, g dbSNP:370363439
322 322 a, g dbSNP:377567620
325 325 c, t dbSNP:755145462
327 327 a, g dbSNP:749324672
329 329 a, g dbSNP:780428375
333 333 a, g dbSNP:756354867
341 341 a, g dbSNP:200066556
342 342 c, g dbSNP:768032940
343 343 a, g dbSNP:373933563
344 344 a, c dbSNP:752163142
353 353 c, t dbSNP:186219547
362 362 -, t dbSNP:754532709
364 364 a, g dbSNP:762525821
366 366 a, g dbSNP:774935889
378 378 a, g dbSNP:764895665
379 379 a, g dbSNP:566073131
388 388 c, t dbSNP:752821879
391 391 a, g dbSNP:770828628
401 401 a, g dbSNP:746768839
402 402 c, t dbSNP:773216441
404 404 a, c dbSNP:771838146
414 414 a, c dbSNP:370960593
415 415 a, g dbSNP:780328472
453 453 c, t dbSNP:764986581
454 454 a, g, t dbSNP:781255236
455 455 c, t dbSNP:139176541
462 462 c, t dbSNP:147268650
467 467 -, c dbSNP:751319527
467 467 c, t dbSNP:145493619
468 468 a, g dbSNP:141743294
478 478 c, t dbSNP:758787019
479 479 c, t dbSNP:753183614
486 486 a, g dbSNP:377668062
495 495 c, g, t dbSNP:770054643
502 502 a, g dbSNP:745883137
505 505 c, t dbSNP:781477633
510 510 a, g dbSNP:771014475
515 515 a, g dbSNP:747418341
525 525 c, t dbSNP:778052349
528 528 g, t dbSNP:758734560
531 531 c, t dbSNP:144843013
535 535 a, g dbSNP:779382629
536 536 a, g dbSNP:754498750
537 537 c, t dbSNP:753221219
538 538 a, g dbSNP:140262447
542 542 c, t dbSNP:760293523
543 543 -, ccc dbSNP:779774332
543 543 c, t dbSNP:750059541
544 544 a, g dbSNP:767281272
554 554 a, g dbSNP:761685361
557 557 a, g dbSNP:774440655
560 560 c, t dbSNP:141795695
562 562 a, c dbSNP:759716073
597 597 -, t dbSNP:757924445
601 601 a, g dbSNP:764145941
603 603 a, g dbSNP:763029790
604 604 c, t dbSNP:775472022
605 605 a, g dbSNP:766439768
610 610 c, t dbSNP:112753281
632 632 a, g dbSNP:760798462
649 649 g, t dbSNP:773322867
664 664 c, t dbSNP:772217655
665 665 a, g dbSNP:113994140
672 672 a, g dbSNP:774649468
674 674 a, c dbSNP:201983132
676 676 a, g dbSNP:749826585
678 678 a, c dbSNP:143645243
699 699 a, g dbSNP:780596765
706 706 a, t dbSNP:755590703
715 715 c, g dbSNP:371720624
720 720 g, t dbSNP:745306550
724 724 a, g dbSNP:79087668
727 727 a, g dbSNP:756916881
728 728 c, t dbSNP:34837068
745 745 g, t dbSNP:35731866
753 753 a, c dbSNP:775864936
754 754 a, c dbSNP:200558941
760 760 a, c, g dbSNP:773739764
764 764 a, c dbSNP:533095698
776 776 g, t dbSNP:564918219
777 777 c, t dbSNP:746728526
780 780 c, t dbSNP:777559380
782 782 c, t dbSNP:758143303
785 785 a, g dbSNP:281865563
788 788 c, t dbSNP:765119777
789 789 a, g dbSNP:146650383
790 790 a, g dbSNP:753753811
791 791 g, t dbSNP:767649857
792 792 c, t dbSNP:761867849
799 799 a, g dbSNP:751791144
800 800 c, t dbSNP:528557291
801 801 a, g dbSNP:561240990
821 821 c, t dbSNP:775872848
823 823 a, g dbSNP:770028506
825 825 c, t dbSNP:201613485
833 833 c, t dbSNP:777277493
834 834 a, g dbSNP:376385820
844 844 c, g dbSNP:746462801
845 845 c, t dbSNP:777575981
863 863 a, g dbSNP:771717707
871 871 c, g dbSNP:747920863
875 875 a, g dbSNP:778817395
893 893 g, t dbSNP:754699794
903 903 c, t dbSNP:753829444
904 904 a, g dbSNP:765876974
907 907 g, t dbSNP:61924369
909 909 a, g dbSNP:779908231
912 912 g, t dbSNP:199650711
920 920 c, t dbSNP:751596896
927 927 c, t dbSNP:764241108
930 930 a, c dbSNP:763282675
933 933 a, c dbSNP:752826795
939 939 c, t dbSNP:74081707
940 940 a, g dbSNP:759969939
944 944 c, t dbSNP:542029566
966 966 a, c dbSNP:755994241
979 979 a, c, t dbSNP:777944504
980 980 a, g dbSNP:758400992
990 990 c, t dbSNP:753025298
991 991 a, c dbSNP:765322400
1003 1003 c, t dbSNP:772276749
1012 1012 a, g dbSNP:200263143
1022 1022 c, t dbSNP:754218148
1023 1023 a, g dbSNP:201394996
1041 1041 a, g dbSNP:761315405
1043 1043 a, g dbSNP:773561952
1057 1057 a, g dbSNP:375197568
1060 1060 c, t dbSNP:372213429
1068 1068 c, t dbSNP:368850875
1072 1072 c, t dbSNP:774058029
1074 1074 c, t dbSNP:374695088
1079 1079 -, g, gg dbSNP:148197048
1080 1080 g, t dbSNP:74918611
1084 1084 g, t dbSNP:775310173
1085 1085 a, t dbSNP:769543803
1090 1090 a, c dbSNP:745880716
1093 1093 c, t dbSNP:780974681
1098 1098 a, g dbSNP:34778200
1104 1104 c, t dbSNP:748113916
1112 1112 a, c dbSNP:779229187
1124 1124 a, g dbSNP:755578011
1141 1141 a, g dbSNP:775135171
1158 1158 c, t dbSNP:371149992
1159 1159 a, g dbSNP:376845777
1161 1161 a, g dbSNP:757752736
1162 1162 a, c dbSNP:752070986
1173 1173 c, t dbSNP:763656364
1174 1174 a, g dbSNP:762434475
1178 1178 c, t dbSNP:559947948
1179 1179 a, g dbSNP:368347802
1204 1204 c, t dbSNP:764805797
1208 1208 a, g dbSNP:759409673
1215 1215 c, t dbSNP:537302175
1230 1230 c, g dbSNP:776244004
1240 1240 a, g dbSNP:770740860
1260 1260 c, t dbSNP:759688762
1264 1264 a, g dbSNP:202205425
1268 1268 c, t dbSNP:375459191
1269 1269 a, g, t dbSNP:150052192
1271 1271 a, g dbSNP:768917442
1281 1281 g, t dbSNP:529793741
1288 1288 a, g dbSNP:780452958
1298 1298 c, g dbSNP:769860194
1308 1308 c, g, t dbSNP:139421676
1327 1327 c, g dbSNP:757632765
1331 1331 a, g dbSNP:752116352
1346 1346 a, g dbSNP:778192552
1358 1358 a, g dbSNP:757911190
1361 1361 c, g, t dbSNP:76029235
1370 1370 a, g dbSNP:764895755
1375 1375 c, t dbSNP:759164554
1376 1376 a, g dbSNP:577174749
1377 1377 a, c, g dbSNP:370013528
1378 1378 g, t dbSNP:773297758
1390 1390 c, t dbSNP:772094351
1404 1404 c, t dbSNP:141763288
1411 1411 c, t dbSNP:775761309
1413 1413 a, g dbSNP:769884613
1434 1434 c, t dbSNP:746139680
1440 1440 c, t dbSNP:781459043
1451 1451 a, g dbSNP:771210638
1457 1457 a, g dbSNP:747305137
1463 1463 a, c dbSNP:778286825
1489 1489 a, t dbSNP:758856895
1499 1499 a, g dbSNP:748636455
1500 1500 a, c dbSNP:778330311
1503 1503 a, g dbSNP:375407377
1510 1510 a, t dbSNP:754507423
1530 1530 c, t dbSNP:571386763
1556 1556 c, t dbSNP:766000495
1559 1559 c, t dbSNP:755979431
1562 1562 a, g dbSNP:367941464
1576 1576 c, g, t dbSNP:376384105
1579 1579 a, g dbSNP:774422189
1588 1588 a, g dbSNP:765287368
1592 1592 a, t dbSNP:759600108
1597 1597 a, g dbSNP:776720321
1601 1601 c, t dbSNP:151332996
1602 1602 a, g dbSNP:142502371
1621 1621 g, t dbSNP:773620209
1622 1622 a, g dbSNP:371689139
1633 1633 c, t dbSNP:553919252
1635 1635 c, t dbSNP:748722157
1636 1636 c, t dbSNP:779462876
1638 1638 c, t dbSNP:183742526
1652 1652 a, g dbSNP:748766846
1653 1653 a, t dbSNP:779594296
1663 1663 a, t dbSNP:755877569
1666 1666 c, g dbSNP:750068527
1681 1681 c, t dbSNP:767486612
1684 1684 a, c dbSNP:146199468
1687 1687 a, t dbSNP:751460514
1690 1690 c, g dbSNP:764022861
1695 1695 c, t dbSNP:759563559
1696 1696 a, t dbSNP:776727562
1699 1699 g, t dbSNP:766349772
1710 1710 a, g dbSNP:760931731
1712 1712 a, c dbSNP:773422113
1713 1713 c, g dbSNP:772484365
1714 1714 a, g dbSNP:748454609
1718 1718 c, t dbSNP:774727935
1726 1726 a, g dbSNP:769168031
1731 1731 c, t dbSNP:749735572
1740 1740 c, t dbSNP:779653619
1744 1744 a, c dbSNP:769424445
1745 1745 a, g dbSNP:138568653
1747 1747 a, g dbSNP:780931107
1757 1757 a, g dbSNP:556311726
1760 1760 c, g dbSNP:751326939
1766 1766 c, t dbSNP:777597253
1768 1768 c, t dbSNP:281865564
1771 1771 a, t dbSNP:538066196
1789 1789 a, g dbSNP:570770626
1792 1792 c, g dbSNP:552840971
1794 1794 c, g dbSNP:367822804
1797 1797 c, t dbSNP:376123082
1803 1803 c, t dbSNP:760731193
1815 1815 c, t dbSNP:116197349
1831 1831 a, c dbSNP:547914367
1835 1835 c, g dbSNP:560995986
1840 1840 a, c dbSNP:371789655
1842 1842 c, g dbSNP:762118167
1851 1851 a, g dbSNP:774825872
1859 1859 g, t dbSNP:768870075
1860 1860 a, g dbSNP:200460878
1865 1865 a, g dbSNP:201054946
1866 1866 c, t dbSNP:769438599
1871 1871 c, t dbSNP:745306755
1874 1874 c, t dbSNP:781019264
1895 1895 c, t dbSNP:374333566
1901 1901 c, g dbSNP:139901494
1913 1913 c, g dbSNP:777667268
1917 1917 a, g dbSNP:758126980
1921 1921 c, t dbSNP:150121787
1949 1949 a, g dbSNP:778765052
1955 1955 a, g dbSNP:756192425
1956 1956 a, g dbSNP:750464270
1957 1957 c, g dbSNP:371146879
1961 1961 c, t dbSNP:150766064
1962 1962 a, g dbSNP:144062651
1966 1966 g, t dbSNP:751724595
1967 1967 a, c dbSNP:764577468
1975 1975 g, t dbSNP:763169354
1977 1977 a, t dbSNP:776141626
1983 1983 a, c, t dbSNP:748556304
1986 1986 c, t dbSNP:776332277
1995 1995 a, g dbSNP:533432460
2000 2000 c, t dbSNP:370892022
2001 2001 a, c, g dbSNP:149518219
2002 2002 a, g dbSNP:760050261
2010 2010 a, t dbSNP:772922391
2030 2030 c, t dbSNP:771584708
2049 2049 g, t dbSNP:747960166
2065 2065 a, g dbSNP:774182139
2066 2066 c, t dbSNP:192905881
2101 2101 c, t dbSNP:138079613
2109 2109 c, t dbSNP:749279543
2122 2122 a, c, g dbSNP:757362404
2123 2123 a, g dbSNP:747016163
2126 2126 c, g dbSNP:778075325
2135 2135 a, c dbSNP:758594837
2140 2140 a, g dbSNP:752938677
2145 2145 g, t dbSNP:765766362
2147 2147 -, t dbSNP:776696757
2158 2158 g, t dbSNP:368664984
2171 2171 a, c dbSNP:754414301
2173 2173 a, t dbSNP:766728682
2187 2187 a, c, g dbSNP:749854195
2199 2199 a, t dbSNP:767033548
2210 2210 c, t dbSNP:761518408
2218 2218 c, t dbSNP:773978081
2219 2219 a, c dbSNP:768451748
2221 2221 a, g dbSNP:762668703
2223 2223 a, c, g dbSNP:150809651
2233 2233 a, c dbSNP:745792839
2242 2242 c, g dbSNP:200171609
2251 2251 -, tt dbSNP:111643910
2253 2253 c, t dbSNP:3747563
2256 2256 -, cc dbSNP:112291115
2256 2256 c, t dbSNP:3747562
2273 2273 a, g dbSNP:139937830
2276 2276 a, c, g dbSNP:374621616
2286 2286 c, t dbSNP:754215976
2287 2287 a, g dbSNP:780633961
2296 2296 c, g dbSNP:370129051
2306 2306 c, t dbSNP:750913400
2307 2307 c, g dbSNP:766992928
2317 2317 a, g dbSNP:557639324
2323 2323 c, g dbSNP:751217827
2329 2329 c, t dbSNP:376257338
2332 2332 a, g dbSNP:143947284
2336 2336 a, c dbSNP:775196409
2339 2339 a, g dbSNP:769599129
2340 2340 c, t dbSNP:759461345
2346 2346 a, g dbSNP:373302710
2351 2351 a, g dbSNP:370547490
2356 2356 a, t dbSNP:794727934
2365 2365 c, t dbSNP:776619006
2374 2374 c, t dbSNP:572205675
2375 2375 c, g dbSNP:748173327
2380 2380 c, t dbSNP:779314205
2381 2381 a, g dbSNP:377294908
2398 2398 c, t dbSNP:768954477
2399 2399 a, g dbSNP:189093086
2418 2418 c, t dbSNP:199893979
2425 2425 a, g dbSNP:149496604
2435 2435 a, g dbSNP:750904030
2443 2443 c, t dbSNP:781672373
2445 2445 c, t dbSNP:756787066
2458 2458 c, t dbSNP:751021008
2459 2459 a, g dbSNP:369790443
2462 2462 c, t dbSNP:758085094
2465 2465 a, t dbSNP:752387857
2468 2468 a, c dbSNP:765001355
2470 2470 c, t dbSNP:377228096
2472 2472 c, t dbSNP:374657704
2473 2473 a, g dbSNP:369077719
2476 2476 a, g dbSNP:371991440
2480 2480 a, g dbSNP:750226436
2482 2482 a, g dbSNP:774624657
2498 2498 a, g dbSNP:768827796
2499 2499 a, t dbSNP:749541698
2501 2501 a, g dbSNP:775721420
2508 2508 a, c dbSNP:770055515
2509 2509 c, t dbSNP:746199700
2510 2510 a, g dbSNP:779059953
2512 2512 a, g dbSNP:757810750
2523 2523 a, t dbSNP:757496174
2525 2525 a, t dbSNP:747481880
2543 2543 a, t dbSNP:777329767
2546 2546 a, g dbSNP:567656128
2547 2547 c, t dbSNP:137985321
2548 2548 a, g dbSNP:150287042
2556 2556 c, t dbSNP:570186739
2563 2563 a, g dbSNP:753625155
2570 2570 c, t dbSNP:138452760
2572 2572 g, t dbSNP:760738396
2576 2576 a, g dbSNP:375420597
2578 2578 a, g dbSNP:370967125
2590 2590 c, t dbSNP:3827522
2604 2604 a, g dbSNP:775601706
2616 2616 c, g dbSNP:727504104
2618 2618 -, ta dbSNP:768660106
2619 2619 c, t dbSNP:148989635
2620 2620 a, g dbSNP:777019107
2622 2622 c, t dbSNP:771279388
2623 2623 a, g dbSNP:145860632
2630 2630 a, g dbSNP:778196919
2632 2632 -, gat dbSNP:557205452
2637 2637 c, t dbSNP:149852787
2648 2648 c, t dbSNP:747655113
2655 2655 c, t dbSNP:778452934
2658 2658 -, ctc dbSNP:779393661
2658 2658 c, g dbSNP:35854729
2664 2664 c, t dbSNP:529575327
2665 2665 g, t dbSNP:146670726
2667 2667 c, t dbSNP:755963146
2670 2670 a, g dbSNP:143240342
2678 2678 -, aag dbSNP:758094682
2684 2684 a, g dbSNP:768039518
2690 2690 c, t dbSNP:374409698
2698 2698 c, t dbSNP:752866274
2713 2713 c, t dbSNP:765199745
2714 2714 a, g, t dbSNP:776819993
2717 2717 c, t dbSNP:200984524
2718 2718 a, g dbSNP:760964320
2721 2721 a, g dbSNP:549385436
2724 2724 a, g dbSNP:375310663
2734 2734 c, t dbSNP:201705679
2736 2736 c, t dbSNP:538043977
2739 2739 a, g dbSNP:748585713
2742 2742 c, t dbSNP:778528977
2743 2743 c, g dbSNP:746765797
2751 2751 c, t dbSNP:768050274
2754 2754 a, t dbSNP:139855191
2755 2755 c, t dbSNP:779783898
2758 2758 c, t dbSNP:150545495
2760 2760 a, g dbSNP:377290931
2766 2766 a, c dbSNP:750190848
2776 2776 a, c dbSNP:780823369
2779 2779 c, g dbSNP:142613488
2785 2785 a, g dbSNP:751446088
2788 2788 -, cagaggaca dbSNP:745483751
2793 2793 a, g dbSNP:138524511
2811 2811 a, g dbSNP:759552132
2816 2816 a, g dbSNP:754065513
2823 2823 c, t dbSNP:766549997
2841 2841 c, t dbSNP:376858650
2852 2852 c, t dbSNP:555008439
2853 2853 a, g dbSNP:567492165
2885 2885 a, g dbSNP:200644857
2895 2895 c, g, t dbSNP:372633476
2896 2896 a, g, t dbSNP:147122337
2905 2905 a, g dbSNP:560130870
2920 2920 a, g dbSNP:759888600
2925 2925 a, g dbSNP:542130236
2941 2941 c, t dbSNP:1043652
2953 2953 -, t dbSNP:151151770
2979 2979 a, g dbSNP:572315226
3059 3059 a, g dbSNP:192612214
3068 3068 c, t dbSNP:537460102
3078 3078 c, t dbSNP:576421272
3102 3102 a, c dbSNP:558237556
3111 3111 c, t dbSNP:1043656
3145 3145 -, at dbSNP:558821449
3145 3145 c, t dbSNP:761391791
3185 3185 a, g dbSNP:570071895
3216 3216 a, g dbSNP:547699182
3240 3240 c, g dbSNP:768200105
3248 3248 g, t dbSNP:17091220
3252 3252 g, t dbSNP:568438224
3257 3257 a, g, t dbSNP:745482621
3260 3260 c, t dbSNP:781107806
3280 3280 c, g dbSNP:141738298
3286 3286 c, g dbSNP:746977003
3287 3287 a, g dbSNP:777503447
3291 3291 a, c dbSNP:755082741
3298 3298 a, t dbSNP:571674666
3333 3333 a, c dbSNP:187632148
3342 3342 c, g dbSNP:563966550
3367 3367 c, t dbSNP:766425066
3377 3377 g, t dbSNP:12658
3378 3378 c, t dbSNP:750610528
3383 3383 c, t dbSNP:527422458
3392 3392 -, aa dbSNP:76259006
3392 3392 -, a dbSNP:398019285
3396 3396 a, c dbSNP:767986403
3401 3401 -, aa dbSNP:778238511
3402 3402 -, a dbSNP:756462439
3402 3402 -, a dbSNP:68074167
3402 3402 a, c dbSNP:778702730
3415 3415 c, t dbSNP:762030087
3443 3443 g, t dbSNP:757584408
3444 3444 -, aa dbSNP:769616581
3463 3463 c, t dbSNP:775224782
3531 3531 -, t dbSNP:567650778
3547 3547 c, t dbSNP:749474350
3565 3565 g, t dbSNP:147942021
3652 3652 a, g dbSNP:778118882
3686 3686 -, t dbSNP:746752965
3709 3709 a, g dbSNP:756303597
3747 3747 a, g dbSNP:368596743
3750 3750 c, t dbSNP:542060460
3764 3764 a, c dbSNP:551815384
3776 3776 c, t dbSNP:574754036
3782 3782 a, t dbSNP:555892431
3794 3794 c, t dbSNP:749282719
3799 3799 a, t dbSNP:752821017
3833 3833 a, c dbSNP:73126459
3862 3862 a, g dbSNP:537803462
3873 3873 a, g dbSNP:756229345
3885 3885 -, t dbSNP:759701217
3885 3885 -, t dbSNP:201368761
3894 3894 c, t dbSNP:543795157
3896 3896 c, g dbSNP:533279850
3897 3897 c, t dbSNP:11181513
3921 3921 a, g dbSNP:182902189
3929 3929 a, c dbSNP:751878241
3961 3961 c, t dbSNP:557897526
4020 4020 c, t dbSNP:192161217
4032 4032 c, t dbSNP:572465188
4124 4124 -, ttgagtactgtaagt dbSNP:376939377
4125 4125 -, tgagtactgtaagtt dbSNP:572638131
4133 4133 g, t dbSNP:1669933
4215 4215 c, t dbSNP:535656837
4218 4218 c, t dbSNP:568374912
4244 4244 a, g dbSNP:1051453
4300 4300 a, c dbSNP:3168685

Target ORF information:

RefSeq Version NM_153026
Organism Homo sapiens (human)
Definition Homo sapiens prickle homolog 1 (PRICKLE1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_153026

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGCCTTTGG AGATGGAGCC CAAGATGAGC AAACTGGCCT TTGGCTGTCA GAGAAGTTCC 
ACATCAGATG ATGACTCTGG CTGTGCATTG GAGGAGTACG CCTGGGTCCC CCCGGGCCTG
AGACCAGAGC AGATCCAGCT CTATTTTGCT TGCTTACCAG AGGAAAAAGT TCCTTACGTT
AACAGCCCCG GAGAGAAGCA TCGGATTAAA CAGCTTTTGT ACCAGTTACC ACCACATGAT
AATGAGGTAC GGTATTGCCA GTCTTTGAGT GAAGAGGAGA AAAAAGAGTT GCAGGTGTTC
AGTGCTCAGC GGAAGAAAGA AGCACTGGGA AGAGGAACAA TTAAGCTTCT GTCCAGAGCA
GTCATGCATG CTGTGTGTGA GCAGTGTGGT TTGAAGATAA ATGGAGGTGA AGTTGCAGTG
TTCGCCTCCC GTGCGGGCCC TGGTGTGTGC TGGCACCCAT CCTGTTTTGT CTGTTTCACG
TGTAATGAGC TGCTGGTCGA CCTCATCTAT TTTTATCAGG ATGGAAAAAT TCACTGTGGC
AGGCACCATG CAGAACTGCT CAAACCACGG TGCTCAGCAT GTGACGAGAT AATTTTTGCT
GATGAGTGCA CAGAAGCTGA GGGTCGCCAT TGGCACATGA AACACTTCTG CTGCCTTGAG
TGTGAAACGG TCCTGGGAGG ACAGAGGTAT ATCATGAAGG ACGGCCGCCC CTTCTGCTGT
GGCTGTTTTG AGTCTCTCTA TGCGGAGTAC TGTGAAACCT GTGGGGAACA TATTGGTGTG
GACCATGCAC AGATGACCTA TGACGGGCAG CACTGGCACG CCACGGAAGC CTGCTTTTCT
TGTGCCCAGT GTAAAGCCTC TTTGTTGGGA TGTCCCTTCC TTCCCAAACA GGGTCAGATT
TACTGCTCAA AAACGTGCAG TCTTGGTGAA GACGTCCATG CCTCTGATTC TTCCGACTCT
GCATTTCAGT CAGCTCGATC AAGAGACTCC CGAAGAAGTG TCCGAATGGG CAAGAGCAGC
CGGTCAGCAG ATCAGTGTAG ACAGTCTCTC CTCTTATCGC CTGCTCTGAA CTACAAGTTT
CCTGGCCTCT CAGGCAATGC TGATGACACC CTTTCTCGAA AATTGGATGA TCTGAGTCTC
TCCAGACAAG GAACAAGTTT TGCCAGTGAA GAATTTTGGA AAGGCAGAGT AGAGCAGGAA
ACTCCAGAAG ACCCTGAAGA ATGGGCTGAT CATGAAGATT ATATGACGCA GCTCCTCCTC
AAGTTTGGTG ATAAAAGCCT CTTTCAGCCA CAGCCCAATG AGATGGATAT TCGAGCCAGT
GAGCACTGGA TATCTGATAA CATGGTTAAA AGTAAGACCG AGTTAAAGCA AAATAACCAG
AGCCTTGCAA GTAAAAAATA CCAGTCTGAT ATGTACTGGG CACAGTCACA AGATGGACTG
GGCGATTCTG CTTATGGCAG CCACCCAGGC CCTGCAAGCA GTAGAAGGCT TCAGGAATTG
GAACTGGACC ATGGGGCTTC AGGGTATAAT CATGATGAAA CACAGTGGTA TGAAGATTCC
CTGGAGTGTC TGTCAGACCT GAAACCAGAG CAAAGTGTTC GGGATTCGAT GGATTCTTTG
GCATTGTCCA ATATCACAGG GGCTTCGGTG GATGGAGAAA ACAAGCCAAG GCCATCATTG
TATTCTCTGC AAAATTTTGA GGAGATGGAA ACAGAAGATT GTGAGAAGAT GAGCAATATG
GGAACTTTGA ACTCTTCCAT GCTGCACAGG AGTGCAGAGT CCTTAAAGAG TCTAAGTTCA
GAGTTGTGTC CAGAGAAAAT CCTGCCTGAA GAGAAGCCAG TACATCTGCC AGTGCTCAGA
AGGTCCAAGT CTCAATCCAG ACCCCAGCAG GTCAAGTTTT CTGATGATGT CATTGACAAT
GGGAACTATG ACATTGAAAT CCGGCAGCCT CCGATGAGTG AAAGGACTCG GAGACGCGTC
TACAATTTTG AAGAGAGGGG ATCCAGGTCT CATCACCACC GCCGCCGGAG AAGTAGAAAG
TCCCGCTCCG ACAATGCCCT GAATCTTGTT ACAGAAAGAA AATACTCTCC CAAGGACAGA
CTGCGGCTGT ACACCCCCGA TAACTATGAG AAATTTATAC AGAATAAAAG TGCCCGGGAG
ATCCAAGCAT ACATCCAGAA TGCTGATCTC TACGGACAGT ACGCCCATGC CACTTCCGAT
TATGGCCTGC AGAACCCAGG AATGAATCGG TTTCTGGGAC TCTACGGCGA GGATGATGAT
TCCTGGTGTT CTTCCTCCTC CTCCTCTTCC GACTCGGAAG AAGAAGGATA TTTTCTTGGA
CAACCAATCC CTCAACCCCG GCCACAGAGA TTTGCCTACT ATACAGATGA CCTTTCTAGT
CCACCATCTG CACTTCCCAC CCCTCAGTTT GGTCAGAGGA CAACAAAATC CAAGAAGAAA
AAGGGACACA AGGGCAAAAA TTGTATTATT TCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22315
Accession Version NM_001144883.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2496bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 24-JUL-2015
Organism Homo sapiens (human)
Product prickle-like protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA321918.1, AK122881.1, CN390789.1, AK056189.1, AC079601.25 and BE858932.1. Summary: This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK122881.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGCCTTTGG AGATGGAGCC CAAGATGAGC AAACTGGCCT TTGGCTGTCA GAGAAGTTCC 
ACATCAGATG ATGACTCTGG CTGTGCATTG GAGGAGTACG CCTGGGTCCC CCCGGGCCTG
AGACCAGAGC AGATCCAGCT CTATTTTGCT TGCTTACCAG AGGAAAAAGT TCCTTACGTT
AACAGCCCCG GAGAGAAGCA TCGGATTAAA CAGCTTTTGT ACCAGTTACC ACCACATGAT
AATGAGGTAC GGTATTGCCA GTCTTTGAGT GAAGAGGAGA AAAAAGAGTT GCAGGTGTTC
AGTGCTCAGC GGAAGAAAGA AGCACTGGGA AGAGGAACAA TTAAGCTTCT GTCCAGAGCA
GTCATGCATG CTGTGTGTGA GCAGTGTGGT TTGAAGATAA ATGGAGGTGA AGTTGCAGTG
TTCGCCTCCC GTGCGGGCCC TGGTGTGTGC TGGCACCCAT CCTGTTTTGT CTGTTTCACG
TGTAATGAGC TGCTGGTCGA CCTCATCTAT TTTTATCAGG ATGGAAAAAT TCACTGTGGC
AGGCACCATG CAGAACTGCT CAAACCACGG TGCTCAGCAT GTGACGAGAT AATTTTTGCT
GATGAGTGCA CAGAAGCTGA GGGTCGCCAT TGGCACATGA AACACTTCTG CTGCCTTGAG
TGTGAAACGG TCCTGGGAGG ACAGAGGTAT ATCATGAAGG ACGGCCGCCC CTTCTGCTGT
GGCTGTTTTG AGTCTCTCTA TGCGGAGTAC TGTGAAACCT GTGGGGAACA TATTGGTGTG
GACCATGCAC AGATGACCTA TGACGGGCAG CACTGGCACG CCACGGAAGC CTGCTTTTCT
TGTGCCCAGT GTAAAGCCTC TTTGTTGGGA TGTCCCTTCC TTCCCAAACA GGGTCAGATT
TACTGCTCAA AAACGTGCAG TCTTGGTGAA GACGTCCATG CCTCTGATTC TTCCGACTCT
GCATTTCAGT CAGCTCGATC AAGAGACTCC CGAAGAAGTG TCCGAATGGG CAAGAGCAGC
CGGTCAGCAG ATCAGTGTAG ACAGTCTCTC CTCTTATCGC CTGCTCTGAA CTACAAGTTT
CCTGGCCTCT CAGGCAATGC TGATGACACC CTTTCTCGAA AATTGGATGA TCTGAGTCTC
TCCAGACAAG GAACAAGTTT TGCCAGTGAA GAATTTTGGA AAGGCAGAGT AGAGCAGGAA
ACTCCAGAAG ACCCTGAAGA ATGGGCTGAT CATGAAGATT ATATGACGCA GCTCCTCCTC
AAGTTTGGTG ATAAAAGCCT CTTTCAGCCA CAGCCCAATG AGATGGATAT TCGAGCCAGT
GAGCACTGGA TATCTGATAA CATGGTTAAA AGTAAGACCG AGTTAAAGCA AAATAACCAG
AGCCTTGCAA GTAAAAAATA CCAGTCTGAT ATGTACTGGG CACAGTCACA AGATGGACTG
GGCGATTCTG CTTATGGCAG CCACCCAGGC CCTGCAAGCA GTAGAAGGCT TCAGGAATTG
GAACTGGACC ATGGGGCTTC AGGGTATAAT CATGATGAAA CACAGTGGTA TGAAGATTCC
CTGGAGTGTC TGTCAGACCT GAAACCAGAG CAAAGTGTTC GGGATTCGAT GGATTCTTTG
GCATTGTCCA ATATCACAGG GGCTTCGGTG GATGGAGAAA ACAAGCCAAG GCCATCATTG
TATTCTCTGC AAAATTTTGA GGAGATGGAA ACAGAAGATT GTGAGAAGAT GAGCAATATG
GGAACTTTGA ACTCTTCCAT GCTGCACAGG AGTGCAGAGT CCTTAAAGAG TCTAAGTTCA
GAGTTGTGTC CAGAGAAAAT CCTGCCTGAA GAGAAGCCAG TACATCTGCC AGTGCTCAGA
AGGTCCAAGT CTCAATCCAG ACCCCAGCAG GTCAAGTTTT CTGATGATGT CATTGACAAT
GGGAACTATG ACATTGAAAT CCGGCAGCCT CCGATGAGTG AAAGGACTCG GAGACGCGTC
TACAATTTTG AAGAGAGGGG ATCCAGGTCT CATCACCACC GCCGCCGGAG AAGTAGAAAG
TCCCGCTCCG ACAATGCCCT GAATCTTGTT ACAGAAAGAA AATACTCTCC CAAGGACAGA
CTGCGGCTGT ACACCCCCGA TAACTATGAG AAATTTATAC AGAATAAAAG TGCCCGGGAG
ATCCAAGCAT ACATCCAGAA TGCTGATCTC TACGGACAGT ACGCCCATGC CACTTCCGAT
TATGGCCTGC AGAACCCAGG AATGAATCGG TTTCTGGGAC TCTACGGCGA GGATGATGAT
TCCTGGTGTT CTTCCTCCTC CTCCTCTTCC GACTCGGAAG AAGAAGGATA TTTTCTTGGA
CAACCAATCC CTCAACCCCG GCCACAGAGA TTTGCCTACT ATACAGATGA CCTTTCTAGT
CCACCATCTG CACTTCCCAC CCCTCAGTTT GGTCAGAGGA CAACAAAATC CAAGAAGAAA
AAGGGACACA AGGGCAAAAA TTGTATTATT TCTTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001138355.1
CDS284..2779
Misc Feature(1)257..259(+)
Misc Feature(2)347..637(+)
Misc Feature(3)659..835(+)
Misc Feature(4)659..829(+)
Misc Feature(5)848..1015(+)
Misc Feature(6)854..1009(+)
Misc Feature(7)1028..1204(+)
Misc Feature(8)1034..1201(+)
Misc Feature(9)2765..2767(+)
Exon (1)1..238
Gene:PRICKLE1
Gene Synonym:
Exon (2)239..415
Gene:PRICKLE1
Gene Synonym:
Exon (3)416..529
Gene:PRICKLE1
Gene Synonym:
Exon (4)530..667
Gene:PRICKLE1
Gene Synonym:
Exon (5)668..871
Gene:PRICKLE1
Gene Synonym:
Exon (6)872..1058
Gene:PRICKLE1
Gene Synonym:
Exon (7)1059..1922
Gene:PRICKLE1
Gene Synonym:
Exon (8)1923..4250
Gene:PRICKLE1
Gene Synonym:
Translation
Position Chain Variation Link
10 10 a, g dbSNP:12322471
48 48 a, g dbSNP:145598574
68 68 a, g dbSNP:7315823
78 78 c, t dbSNP:188187954
91 91 g, t dbSNP:75377876
100 100 a, c dbSNP:140455644
106 106 a, g dbSNP:780074084
139 139 a, c dbSNP:56996689
227 227 a, g dbSNP:571399485
237 237 g, t dbSNP:534032095
242 242 c, t dbSNP:770613473
244 244 a, g dbSNP:370363439
251 251 a, g dbSNP:377567620
254 254 c, t dbSNP:755145462
256 256 a, g dbSNP:749324672
258 258 a, g dbSNP:780428375
262 262 a, g dbSNP:756354867
270 270 a, g dbSNP:200066556
271 271 c, g dbSNP:768032940
272 272 a, g dbSNP:373933563
273 273 a, c dbSNP:752163142
282 282 c, t dbSNP:186219547
291 291 -, t dbSNP:754532709
293 293 a, g dbSNP:762525821
295 295 a, g dbSNP:774935889
307 307 a, g dbSNP:764895665
308 308 a, g dbSNP:566073131
317 317 c, t dbSNP:752821879
320 320 a, g dbSNP:770828628
330 330 a, g dbSNP:746768839
331 331 c, t dbSNP:773216441
333 333 a, c dbSNP:771838146
343 343 a, c dbSNP:370960593
344 344 a, g dbSNP:780328472
382 382 c, t dbSNP:764986581
383 383 a, g, t dbSNP:781255236
384 384 c, t dbSNP:139176541
391 391 c, t dbSNP:147268650
396 396 -, c dbSNP:751319527
396 396 c, t dbSNP:145493619
397 397 a, g dbSNP:141743294
407 407 c, t dbSNP:758787019
408 408 c, t dbSNP:753183614
415 415 a, g dbSNP:377668062
424 424 c, g, t dbSNP:770054643
431 431 a, g dbSNP:745883137
434 434 c, t dbSNP:781477633
439 439 a, g dbSNP:771014475
444 444 a, g dbSNP:747418341
454 454 c, t dbSNP:778052349
457 457 g, t dbSNP:758734560
460 460 c, t dbSNP:144843013
464 464 a, g dbSNP:779382629
465 465 a, g dbSNP:754498750
466 466 c, t dbSNP:753221219
467 467 a, g dbSNP:140262447
471 471 c, t dbSNP:760293523
472 472 -, ccc dbSNP:779774332
472 472 c, t dbSNP:750059541
473 473 a, g dbSNP:767281272
483 483 a, g dbSNP:761685361
486 486 a, g dbSNP:774440655
489 489 c, t dbSNP:141795695
491 491 a, c dbSNP:759716073
526 526 -, t dbSNP:757924445
530 530 a, g dbSNP:764145941
532 532 a, g dbSNP:763029790
533 533 c, t dbSNP:775472022
534 534 a, g dbSNP:766439768
539 539 c, t dbSNP:112753281
561 561 a, g dbSNP:760798462
578 578 g, t dbSNP:773322867
593 593 c, t dbSNP:772217655
594 594 a, g dbSNP:113994140
601 601 a, g dbSNP:774649468
603 603 a, c dbSNP:201983132
605 605 a, g dbSNP:749826585
607 607 a, c dbSNP:143645243
628 628 a, g dbSNP:780596765
635 635 a, t dbSNP:755590703
644 644 c, g dbSNP:371720624
649 649 g, t dbSNP:745306550
653 653 a, g dbSNP:79087668
656 656 a, g dbSNP:756916881
657 657 c, t dbSNP:34837068
674 674 g, t dbSNP:35731866
682 682 a, c dbSNP:775864936
683 683 a, c dbSNP:200558941
689 689 a, c, g dbSNP:773739764
693 693 a, c dbSNP:533095698
705 705 g, t dbSNP:564918219
706 706 c, t dbSNP:746728526
709 709 c, t dbSNP:777559380
711 711 c, t dbSNP:758143303
714 714 a, g dbSNP:281865563
717 717 c, t dbSNP:765119777
718 718 a, g dbSNP:146650383
719 719 a, g dbSNP:753753811
720 720 g, t dbSNP:767649857
721 721 c, t dbSNP:761867849
728 728 a, g dbSNP:751791144
729 729 c, t dbSNP:528557291
730 730 a, g dbSNP:561240990
750 750 c, t dbSNP:775872848
752 752 a, g dbSNP:770028506
754 754 c, t dbSNP:201613485
762 762 c, t dbSNP:777277493
763 763 a, g dbSNP:376385820
773 773 c, g dbSNP:746462801
774 774 c, t dbSNP:777575981
792 792 a, g dbSNP:771717707
800 800 c, g dbSNP:747920863
804 804 a, g dbSNP:778817395
822 822 g, t dbSNP:754699794
832 832 c, t dbSNP:753829444
833 833 a, g dbSNP:765876974
836 836 g, t dbSNP:61924369
838 838 a, g dbSNP:779908231
841 841 g, t dbSNP:199650711
849 849 c, t dbSNP:751596896
856 856 c, t dbSNP:764241108
859 859 a, c dbSNP:763282675
862 862 a, c dbSNP:752826795
868 868 c, t dbSNP:74081707
869 869 a, g dbSNP:759969939
873 873 c, t dbSNP:542029566
895 895 a, c dbSNP:755994241
908 908 a, c, t dbSNP:777944504
909 909 a, g dbSNP:758400992
919 919 c, t dbSNP:753025298
920 920 a, c dbSNP:765322400
932 932 c, t dbSNP:772276749
941 941 a, g dbSNP:200263143
951 951 c, t dbSNP:754218148
952 952 a, g dbSNP:201394996
970 970 a, g dbSNP:761315405
972 972 a, g dbSNP:773561952
986 986 a, g dbSNP:375197568
989 989 c, t dbSNP:372213429
997 997 c, t dbSNP:368850875
1001 1001 c, t dbSNP:774058029
1003 1003 c, t dbSNP:374695088
1008 1008 -, g, gg dbSNP:148197048
1009 1009 g, t dbSNP:74918611
1013 1013 g, t dbSNP:775310173
1014 1014 a, t dbSNP:769543803
1019 1019 a, c dbSNP:745880716
1022 1022 c, t dbSNP:780974681
1027 1027 a, g dbSNP:34778200
1033 1033 c, t dbSNP:748113916
1041 1041 a, c dbSNP:779229187
1053 1053 a, g dbSNP:755578011
1070 1070 a, g dbSNP:775135171
1087 1087 c, t dbSNP:371149992
1088 1088 a, g dbSNP:376845777
1090 1090 a, g dbSNP:757752736
1091 1091 a, c dbSNP:752070986
1102 1102 c, t dbSNP:763656364
1103 1103 a, g dbSNP:762434475
1107 1107 c, t dbSNP:559947948
1108 1108 a, g dbSNP:368347802
1133 1133 c, t dbSNP:764805797
1137 1137 a, g dbSNP:759409673
1144 1144 c, t dbSNP:537302175
1159 1159 c, g dbSNP:776244004
1169 1169 a, g dbSNP:770740860
1189 1189 c, t dbSNP:759688762
1193 1193 a, g dbSNP:202205425
1197 1197 c, t dbSNP:375459191
1198 1198 a, g, t dbSNP:150052192
1200 1200 a, g dbSNP:768917442
1210 1210 g, t dbSNP:529793741
1217 1217 a, g dbSNP:780452958
1227 1227 c, g dbSNP:769860194
1237 1237 c, g, t dbSNP:139421676
1256 1256 c, g dbSNP:757632765
1260 1260 a, g dbSNP:752116352
1275 1275 a, g dbSNP:778192552
1287 1287 a, g dbSNP:757911190
1290 1290 c, g, t dbSNP:76029235
1299 1299 a, g dbSNP:764895755
1304 1304 c, t dbSNP:759164554
1305 1305 a, g dbSNP:577174749
1306 1306 a, c, g dbSNP:370013528
1307 1307 g, t dbSNP:773297758
1319 1319 c, t dbSNP:772094351
1333 1333 c, t dbSNP:141763288
1340 1340 c, t dbSNP:775761309
1342 1342 a, g dbSNP:769884613
1363 1363 c, t dbSNP:746139680
1369 1369 c, t dbSNP:781459043
1380 1380 a, g dbSNP:771210638
1386 1386 a, g dbSNP:747305137
1392 1392 a, c dbSNP:778286825
1418 1418 a, t dbSNP:758856895
1428 1428 a, g dbSNP:748636455
1429 1429 a, c dbSNP:778330311
1432 1432 a, g dbSNP:375407377
1439 1439 a, t dbSNP:754507423
1459 1459 c, t dbSNP:571386763
1485 1485 c, t dbSNP:766000495
1488 1488 c, t dbSNP:755979431
1491 1491 a, g dbSNP:367941464
1505 1505 c, g, t dbSNP:376384105
1508 1508 a, g dbSNP:774422189
1517 1517 a, g dbSNP:765287368
1521 1521 a, t dbSNP:759600108
1526 1526 a, g dbSNP:776720321
1530 1530 c, t dbSNP:151332996
1531 1531 a, g dbSNP:142502371
1550 1550 g, t dbSNP:773620209
1551 1551 a, g dbSNP:371689139
1562 1562 c, t dbSNP:553919252
1564 1564 c, t dbSNP:748722157
1565 1565 c, t dbSNP:779462876
1567 1567 c, t dbSNP:183742526
1581 1581 a, g dbSNP:748766846
1582 1582 a, t dbSNP:779594296
1592 1592 a, t dbSNP:755877569
1595 1595 c, g dbSNP:750068527
1610 1610 c, t dbSNP:767486612
1613 1613 a, c dbSNP:146199468
1616 1616 a, t dbSNP:751460514
1619 1619 c, g dbSNP:764022861
1624 1624 c, t dbSNP:759563559
1625 1625 a, t dbSNP:776727562
1628 1628 g, t dbSNP:766349772
1639 1639 a, g dbSNP:760931731
1641 1641 a, c dbSNP:773422113
1642 1642 c, g dbSNP:772484365
1643 1643 a, g dbSNP:748454609
1647 1647 c, t dbSNP:774727935
1655 1655 a, g dbSNP:769168031
1660 1660 c, t dbSNP:749735572
1669 1669 c, t dbSNP:779653619
1673 1673 a, c dbSNP:769424445
1674 1674 a, g dbSNP:138568653
1676 1676 a, g dbSNP:780931107
1686 1686 a, g dbSNP:556311726
1689 1689 c, g dbSNP:751326939
1695 1695 c, t dbSNP:777597253
1697 1697 c, t dbSNP:281865564
1700 1700 a, t dbSNP:538066196
1718 1718 a, g dbSNP:570770626
1721 1721 c, g dbSNP:552840971
1723 1723 c, g dbSNP:367822804
1726 1726 c, t dbSNP:376123082
1732 1732 c, t dbSNP:760731193
1744 1744 c, t dbSNP:116197349
1760 1760 a, c dbSNP:547914367
1764 1764 c, g dbSNP:560995986
1769 1769 a, c dbSNP:371789655
1771 1771 c, g dbSNP:762118167
1780 1780 a, g dbSNP:774825872
1788 1788 g, t dbSNP:768870075
1789 1789 a, g dbSNP:200460878
1794 1794 a, g dbSNP:201054946
1795 1795 c, t dbSNP:769438599
1800 1800 c, t dbSNP:745306755
1803 1803 c, t dbSNP:781019264
1824 1824 c, t dbSNP:374333566
1830 1830 c, g dbSNP:139901494
1842 1842 c, g dbSNP:777667268
1846 1846 a, g dbSNP:758126980
1850 1850 c, t dbSNP:150121787
1878 1878 a, g dbSNP:778765052
1884 1884 a, g dbSNP:756192425
1885 1885 a, g dbSNP:750464270
1886 1886 c, g dbSNP:371146879
1890 1890 c, t dbSNP:150766064
1891 1891 a, g dbSNP:144062651
1895 1895 g, t dbSNP:751724595
1896 1896 a, c dbSNP:764577468
1904 1904 g, t dbSNP:763169354
1906 1906 a, t dbSNP:776141626
1912 1912 a, c, t dbSNP:748556304
1915 1915 c, t dbSNP:776332277
1924 1924 a, g dbSNP:533432460
1929 1929 c, t dbSNP:370892022
1930 1930 a, c, g dbSNP:149518219
1931 1931 a, g dbSNP:760050261
1939 1939 a, t dbSNP:772922391
1959 1959 c, t dbSNP:771584708
1978 1978 g, t dbSNP:747960166
1994 1994 a, g dbSNP:774182139
1995 1995 c, t dbSNP:192905881
2030 2030 c, t dbSNP:138079613
2038 2038 c, t dbSNP:749279543
2051 2051 a, c, g dbSNP:757362404
2052 2052 a, g dbSNP:747016163
2055 2055 c, g dbSNP:778075325
2064 2064 a, c dbSNP:758594837
2069 2069 a, g dbSNP:752938677
2074 2074 g, t dbSNP:765766362
2076 2076 -, t dbSNP:776696757
2087 2087 g, t dbSNP:368664984
2100 2100 a, c dbSNP:754414301
2102 2102 a, t dbSNP:766728682
2116 2116 a, c, g dbSNP:749854195
2128 2128 a, t dbSNP:767033548
2139 2139 c, t dbSNP:761518408
2147 2147 c, t dbSNP:773978081
2148 2148 a, c dbSNP:768451748
2150 2150 a, g dbSNP:762668703
2152 2152 a, c, g dbSNP:150809651
2162 2162 a, c dbSNP:745792839
2171 2171 c, g dbSNP:200171609
2180 2180 -, tt dbSNP:111643910
2182 2182 c, t dbSNP:3747563
2185 2185 -, cc dbSNP:112291115
2185 2185 c, t dbSNP:3747562
2202 2202 a, g dbSNP:139937830
2205 2205 a, c, g dbSNP:374621616
2215 2215 c, t dbSNP:754215976
2216 2216 a, g dbSNP:780633961
2225 2225 c, g dbSNP:370129051
2235 2235 c, t dbSNP:750913400
2236 2236 c, g dbSNP:766992928
2246 2246 a, g dbSNP:557639324
2252 2252 c, g dbSNP:751217827
2258 2258 c, t dbSNP:376257338
2261 2261 a, g dbSNP:143947284
2265 2265 a, c dbSNP:775196409
2268 2268 a, g dbSNP:769599129
2269 2269 c, t dbSNP:759461345
2275 2275 a, g dbSNP:373302710
2280 2280 a, g dbSNP:370547490
2285 2285 a, t dbSNP:794727934
2294 2294 c, t dbSNP:776619006
2303 2303 c, t dbSNP:572205675
2304 2304 c, g dbSNP:748173327
2309 2309 c, t dbSNP:779314205
2310 2310 a, g dbSNP:377294908
2327 2327 c, t dbSNP:768954477
2328 2328 a, g dbSNP:189093086
2347 2347 c, t dbSNP:199893979
2354 2354 a, g dbSNP:149496604
2364 2364 a, g dbSNP:750904030
2372 2372 c, t dbSNP:781672373
2374 2374 c, t dbSNP:756787066
2387 2387 c, t dbSNP:751021008
2388 2388 a, g dbSNP:369790443
2391 2391 c, t dbSNP:758085094
2394 2394 a, t dbSNP:752387857
2397 2397 a, c dbSNP:765001355
2399 2399 c, t dbSNP:377228096
2401 2401 c, t dbSNP:374657704
2402 2402 a, g dbSNP:369077719
2405 2405 a, g dbSNP:371991440
2409 2409 a, g dbSNP:750226436
2411 2411 a, g dbSNP:774624657
2427 2427 a, g dbSNP:768827796
2428 2428 a, t dbSNP:749541698
2430 2430 a, g dbSNP:775721420
2437 2437 a, c dbSNP:770055515
2438 2438 c, t dbSNP:746199700
2439 2439 a, g dbSNP:779059953
2441 2441 a, g dbSNP:757810750
2452 2452 a, t dbSNP:757496174
2454 2454 a, t dbSNP:747481880
2472 2472 a, t dbSNP:777329767
2475 2475 a, g dbSNP:567656128
2476 2476 c, t dbSNP:137985321
2477 2477 a, g dbSNP:150287042
2485 2485 c, t dbSNP:570186739
2492 2492 a, g dbSNP:753625155
2499 2499 c, t dbSNP:138452760
2501 2501 g, t dbSNP:760738396
2505 2505 a, g dbSNP:375420597
2507 2507 a, g dbSNP:370967125
2519 2519 c, t dbSNP:3827522
2533 2533 a, g dbSNP:775601706
2545 2545 c, g dbSNP:727504104
2547 2547 -, ta dbSNP:768660106
2548 2548 c, t dbSNP:148989635
2549 2549 a, g dbSNP:777019107
2551 2551 c, t dbSNP:771279388
2552 2552 a, g dbSNP:145860632
2559 2559 a, g dbSNP:778196919
2561 2561 -, gat dbSNP:557205452
2566 2566 c, t dbSNP:149852787
2577 2577 c, t dbSNP:747655113
2584 2584 c, t dbSNP:778452934
2587 2587 -, ctc dbSNP:779393661
2587 2587 c, g dbSNP:35854729
2593 2593 c, t dbSNP:529575327
2594 2594 g, t dbSNP:146670726
2596 2596 c, t dbSNP:755963146
2599 2599 a, g dbSNP:143240342
2607 2607 -, aag dbSNP:758094682
2613 2613 a, g dbSNP:768039518
2619 2619 c, t dbSNP:374409698
2627 2627 c, t dbSNP:752866274
2642 2642 c, t dbSNP:765199745
2643 2643 a, g, t dbSNP:776819993
2646 2646 c, t dbSNP:200984524
2647 2647 a, g dbSNP:760964320
2650 2650 a, g dbSNP:549385436
2653 2653 a, g dbSNP:375310663
2663 2663 c, t dbSNP:201705679
2665 2665 c, t dbSNP:538043977
2668 2668 a, g dbSNP:748585713
2671 2671 c, t dbSNP:778528977
2672 2672 c, g dbSNP:746765797
2680 2680 c, t dbSNP:768050274
2683 2683 a, t dbSNP:139855191
2684 2684 c, t dbSNP:779783898
2687 2687 c, t dbSNP:150545495
2689 2689 a, g dbSNP:377290931
2695 2695 a, c dbSNP:750190848
2705 2705 a, c dbSNP:780823369
2708 2708 c, g dbSNP:142613488
2714 2714 a, g dbSNP:751446088
2717 2717 -, cagaggaca dbSNP:745483751
2722 2722 a, g dbSNP:138524511
2740 2740 a, g dbSNP:759552132
2745 2745 a, g dbSNP:754065513
2752 2752 c, t dbSNP:766549997
2770 2770 c, t dbSNP:376858650
2781 2781 c, t dbSNP:555008439
2782 2782 a, g dbSNP:567492165
2814 2814 a, g dbSNP:200644857
2824 2824 c, g, t dbSNP:372633476
2825 2825 a, g, t dbSNP:147122337
2834 2834 a, g dbSNP:560130870
2849 2849 a, g dbSNP:759888600
2854 2854 a, g dbSNP:542130236
2870 2870 c, t dbSNP:1043652
2882 2882 -, t dbSNP:151151770
2908 2908 a, g dbSNP:572315226
2988 2988 a, g dbSNP:192612214
2997 2997 c, t dbSNP:537460102
3007 3007 c, t dbSNP:576421272
3031 3031 a, c dbSNP:558237556
3040 3040 c, t dbSNP:1043656
3074 3074 -, at dbSNP:558821449
3074 3074 c, t dbSNP:761391791
3114 3114 a, g dbSNP:570071895
3145 3145 a, g dbSNP:547699182
3169 3169 c, g dbSNP:768200105
3177 3177 g, t dbSNP:17091220
3181 3181 g, t dbSNP:568438224
3186 3186 a, g, t dbSNP:745482621
3189 3189 c, t dbSNP:781107806
3209 3209 c, g dbSNP:141738298
3215 3215 c, g dbSNP:746977003
3216 3216 a, g dbSNP:777503447
3220 3220 a, c dbSNP:755082741
3227 3227 a, t dbSNP:571674666
3262 3262 a, c dbSNP:187632148
3271 3271 c, g dbSNP:563966550
3296 3296 c, t dbSNP:766425066
3306 3306 g, t dbSNP:12658
3307 3307 c, t dbSNP:750610528
3312 3312 c, t dbSNP:527422458
3321 3321 -, aa dbSNP:76259006
3321 3321 -, a dbSNP:398019285
3325 3325 a, c dbSNP:767986403
3330 3330 -, aa dbSNP:778238511
3331 3331 -, a dbSNP:756462439
3331 3331 -, a dbSNP:68074167
3331 3331 a, c dbSNP:778702730
3344 3344 c, t dbSNP:762030087
3372 3372 g, t dbSNP:757584408
3373 3373 -, aa dbSNP:769616581
3392 3392 c, t dbSNP:775224782
3460 3460 -, t dbSNP:567650778
3476 3476 c, t dbSNP:749474350
3494 3494 g, t dbSNP:147942021
3581 3581 a, g dbSNP:778118882
3615 3615 -, t dbSNP:746752965
3638 3638 a, g dbSNP:756303597
3676 3676 a, g dbSNP:368596743
3679 3679 c, t dbSNP:542060460
3693 3693 a, c dbSNP:551815384
3705 3705 c, t dbSNP:574754036
3711 3711 a, t dbSNP:555892431
3723 3723 c, t dbSNP:749282719
3728 3728 a, t dbSNP:752821017
3762 3762 a, c dbSNP:73126459
3791 3791 a, g dbSNP:537803462
3802 3802 a, g dbSNP:756229345
3814 3814 -, t dbSNP:759701217
3814 3814 -, t dbSNP:201368761
3823 3823 c, t dbSNP:543795157
3825 3825 c, g dbSNP:533279850
3826 3826 c, t dbSNP:11181513
3850 3850 a, g dbSNP:182902189
3858 3858 a, c dbSNP:751878241
3890 3890 c, t dbSNP:557897526
3949 3949 c, t dbSNP:192161217
3961 3961 c, t dbSNP:572465188
4053 4053 -, ttgagtactgtaagt dbSNP:376939377
4054 4054 -, tgagtactgtaagtt dbSNP:572638131
4062 4062 g, t dbSNP:1669933
4144 4144 c, t dbSNP:535656837
4147 4147 c, t dbSNP:568374912
4173 4173 a, g dbSNP:1051453
4229 4229 a, c dbSNP:3168685

Target ORF information:

RefSeq Version NM_001144883
Organism Homo sapiens (human)
Definition Homo sapiens prickle homolog 1 (PRICKLE1), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001144883

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGCCTTTGG AGATGGAGCC CAAGATGAGC AAACTGGCCT TTGGCTGTCA GAGAAGTTCC 
ACATCAGATG ATGACTCTGG CTGTGCATTG GAGGAGTACG CCTGGGTCCC CCCGGGCCTG
AGACCAGAGC AGATCCAGCT CTATTTTGCT TGCTTACCAG AGGAAAAAGT TCCTTACGTT
AACAGCCCCG GAGAGAAGCA TCGGATTAAA CAGCTTTTGT ACCAGTTACC ACCACATGAT
AATGAGGTAC GGTATTGCCA GTCTTTGAGT GAAGAGGAGA AAAAAGAGTT GCAGGTGTTC
AGTGCTCAGC GGAAGAAAGA AGCACTGGGA AGAGGAACAA TTAAGCTTCT GTCCAGAGCA
GTCATGCATG CTGTGTGTGA GCAGTGTGGT TTGAAGATAA ATGGAGGTGA AGTTGCAGTG
TTCGCCTCCC GTGCGGGCCC TGGTGTGTGC TGGCACCCAT CCTGTTTTGT CTGTTTCACG
TGTAATGAGC TGCTGGTCGA CCTCATCTAT TTTTATCAGG ATGGAAAAAT TCACTGTGGC
AGGCACCATG CAGAACTGCT CAAACCACGG TGCTCAGCAT GTGACGAGAT AATTTTTGCT
GATGAGTGCA CAGAAGCTGA GGGTCGCCAT TGGCACATGA AACACTTCTG CTGCCTTGAG
TGTGAAACGG TCCTGGGAGG ACAGAGGTAT ATCATGAAGG ACGGCCGCCC CTTCTGCTGT
GGCTGTTTTG AGTCTCTCTA TGCGGAGTAC TGTGAAACCT GTGGGGAACA TATTGGTGTG
GACCATGCAC AGATGACCTA TGACGGGCAG CACTGGCACG CCACGGAAGC CTGCTTTTCT
TGTGCCCAGT GTAAAGCCTC TTTGTTGGGA TGTCCCTTCC TTCCCAAACA GGGTCAGATT
TACTGCTCAA AAACGTGCAG TCTTGGTGAA GACGTCCATG CCTCTGATTC TTCCGACTCT
GCATTTCAGT CAGCTCGATC AAGAGACTCC CGAAGAAGTG TCCGAATGGG CAAGAGCAGC
CGGTCAGCAG ATCAGTGTAG ACAGTCTCTC CTCTTATCGC CTGCTCTGAA CTACAAGTTT
CCTGGCCTCT CAGGCAATGC TGATGACACC CTTTCTCGAA AATTGGATGA TCTGAGTCTC
TCCAGACAAG GAACAAGTTT TGCCAGTGAA GAATTTTGGA AAGGCAGAGT AGAGCAGGAA
ACTCCAGAAG ACCCTGAAGA ATGGGCTGAT CATGAAGATT ATATGACGCA GCTCCTCCTC
AAGTTTGGTG ATAAAAGCCT CTTTCAGCCA CAGCCCAATG AGATGGATAT TCGAGCCAGT
GAGCACTGGA TATCTGATAA CATGGTTAAA AGTAAGACCG AGTTAAAGCA AAATAACCAG
AGCCTTGCAA GTAAAAAATA CCAGTCTGAT ATGTACTGGG CACAGTCACA AGATGGACTG
GGCGATTCTG CTTATGGCAG CCACCCAGGC CCTGCAAGCA GTAGAAGGCT TCAGGAATTG
GAACTGGACC ATGGGGCTTC AGGGTATAAT CATGATGAAA CACAGTGGTA TGAAGATTCC
CTGGAGTGTC TGTCAGACCT GAAACCAGAG CAAAGTGTTC GGGATTCGAT GGATTCTTTG
GCATTGTCCA ATATCACAGG GGCTTCGGTG GATGGAGAAA ACAAGCCAAG GCCATCATTG
TATTCTCTGC AAAATTTTGA GGAGATGGAA ACAGAAGATT GTGAGAAGAT GAGCAATATG
GGAACTTTGA ACTCTTCCAT GCTGCACAGG AGTGCAGAGT CCTTAAAGAG TCTAAGTTCA
GAGTTGTGTC CAGAGAAAAT CCTGCCTGAA GAGAAGCCAG TACATCTGCC AGTGCTCAGA
AGGTCCAAGT CTCAATCCAG ACCCCAGCAG GTCAAGTTTT CTGATGATGT CATTGACAAT
GGGAACTATG ACATTGAAAT CCGGCAGCCT CCGATGAGTG AAAGGACTCG GAGACGCGTC
TACAATTTTG AAGAGAGGGG ATCCAGGTCT CATCACCACC GCCGCCGGAG AAGTAGAAAG
TCCCGCTCCG ACAATGCCCT GAATCTTGTT ACAGAAAGAA AATACTCTCC CAAGGACAGA
CTGCGGCTGT ACACCCCCGA TAACTATGAG AAATTTATAC AGAATAAAAG TGCCCGGGAG
ATCCAAGCAT ACATCCAGAA TGCTGATCTC TACGGACAGT ACGCCCATGC CACTTCCGAT
TATGGCCTGC AGAACCCAGG AATGAATCGG TTTCTGGGAC TCTACGGCGA GGATGATGAT
TCCTGGTGTT CTTCCTCCTC CTCCTCTTCC GACTCGGAAG AAGAAGGATA TTTTCTTGGA
CAACCAATCC CTCAACCCCG GCCACAGAGA TTTGCCTACT ATACAGATGA CCTTTCTAGT
CCACCATCTG CACTTCCCAC CCCTCAGTTT GGTCAGAGGA CAACAAAATC CAAGAAGAAA
AAGGGACACA AGGGCAAAAA TTGTATTATT TCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22315
Accession Version NM_001144882.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2496bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 24-JUL-2015
Organism Homo sapiens (human)
Product prickle-like protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA321918.1, BC114940.1, AC079601.25 and BE858932.1. Summary: This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF399844.1, AK122881.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGCCTTTGG AGATGGAGCC CAAGATGAGC AAACTGGCCT TTGGCTGTCA GAGAAGTTCC 
ACATCAGATG ATGACTCTGG CTGTGCATTG GAGGAGTACG CCTGGGTCCC CCCGGGCCTG
AGACCAGAGC AGATCCAGCT CTATTTTGCT TGCTTACCAG AGGAAAAAGT TCCTTACGTT
AACAGCCCCG GAGAGAAGCA TCGGATTAAA CAGCTTTTGT ACCAGTTACC ACCACATGAT
AATGAGGTAC GGTATTGCCA GTCTTTGAGT GAAGAGGAGA AAAAAGAGTT GCAGGTGTTC
AGTGCTCAGC GGAAGAAAGA AGCACTGGGA AGAGGAACAA TTAAGCTTCT GTCCAGAGCA
GTCATGCATG CTGTGTGTGA GCAGTGTGGT TTGAAGATAA ATGGAGGTGA AGTTGCAGTG
TTCGCCTCCC GTGCGGGCCC TGGTGTGTGC TGGCACCCAT CCTGTTTTGT CTGTTTCACG
TGTAATGAGC TGCTGGTCGA CCTCATCTAT TTTTATCAGG ATGGAAAAAT TCACTGTGGC
AGGCACCATG CAGAACTGCT CAAACCACGG TGCTCAGCAT GTGACGAGAT AATTTTTGCT
GATGAGTGCA CAGAAGCTGA GGGTCGCCAT TGGCACATGA AACACTTCTG CTGCCTTGAG
TGTGAAACGG TCCTGGGAGG ACAGAGGTAT ATCATGAAGG ACGGCCGCCC CTTCTGCTGT
GGCTGTTTTG AGTCTCTCTA TGCGGAGTAC TGTGAAACCT GTGGGGAACA TATTGGTGTG
GACCATGCAC AGATGACCTA TGACGGGCAG CACTGGCACG CCACGGAAGC CTGCTTTTCT
TGTGCCCAGT GTAAAGCCTC TTTGTTGGGA TGTCCCTTCC TTCCCAAACA GGGTCAGATT
TACTGCTCAA AAACGTGCAG TCTTGGTGAA GACGTCCATG CCTCTGATTC TTCCGACTCT
GCATTTCAGT CAGCTCGATC AAGAGACTCC CGAAGAAGTG TCCGAATGGG CAAGAGCAGC
CGGTCAGCAG ATCAGTGTAG ACAGTCTCTC CTCTTATCGC CTGCTCTGAA CTACAAGTTT
CCTGGCCTCT CAGGCAATGC TGATGACACC CTTTCTCGAA AATTGGATGA TCTGAGTCTC
TCCAGACAAG GAACAAGTTT TGCCAGTGAA GAATTTTGGA AAGGCAGAGT AGAGCAGGAA
ACTCCAGAAG ACCCTGAAGA ATGGGCTGAT CATGAAGATT ATATGACGCA GCTCCTCCTC
AAGTTTGGTG ATAAAAGCCT CTTTCAGCCA CAGCCCAATG AGATGGATAT TCGAGCCAGT
GAGCACTGGA TATCTGATAA CATGGTTAAA AGTAAGACCG AGTTAAAGCA AAATAACCAG
AGCCTTGCAA GTAAAAAATA CCAGTCTGAT ATGTACTGGG CACAGTCACA AGATGGACTG
GGCGATTCTG CTTATGGCAG CCACCCAGGC CCTGCAAGCA GTAGAAGGCT TCAGGAATTG
GAACTGGACC ATGGGGCTTC AGGGTATAAT CATGATGAAA CACAGTGGTA TGAAGATTCC
CTGGAGTGTC TGTCAGACCT GAAACCAGAG CAAAGTGTTC GGGATTCGAT GGATTCTTTG
GCATTGTCCA ATATCACAGG GGCTTCGGTG GATGGAGAAA ACAAGCCAAG GCCATCATTG
TATTCTCTGC AAAATTTTGA GGAGATGGAA ACAGAAGATT GTGAGAAGAT GAGCAATATG
GGAACTTTGA ACTCTTCCAT GCTGCACAGG AGTGCAGAGT CCTTAAAGAG TCTAAGTTCA
GAGTTGTGTC CAGAGAAAAT CCTGCCTGAA GAGAAGCCAG TACATCTGCC AGTGCTCAGA
AGGTCCAAGT CTCAATCCAG ACCCCAGCAG GTCAAGTTTT CTGATGATGT CATTGACAAT
GGGAACTATG ACATTGAAAT CCGGCAGCCT CCGATGAGTG AAAGGACTCG GAGACGCGTC
TACAATTTTG AAGAGAGGGG ATCCAGGTCT CATCACCACC GCCGCCGGAG AAGTAGAAAG
TCCCGCTCCG ACAATGCCCT GAATCTTGTT ACAGAAAGAA AATACTCTCC CAAGGACAGA
CTGCGGCTGT ACACCCCCGA TAACTATGAG AAATTTATAC AGAATAAAAG TGCCCGGGAG
ATCCAAGCAT ACATCCAGAA TGCTGATCTC TACGGACAGT ACGCCCATGC CACTTCCGAT
TATGGCCTGC AGAACCCAGG AATGAATCGG TTTCTGGGAC TCTACGGCGA GGATGATGAT
TCCTGGTGTT CTTCCTCCTC CTCCTCTTCC GACTCGGAAG AAGAAGGATA TTTTCTTGGA
CAACCAATCC CTCAACCCCG GCCACAGAGA TTTGCCTACT ATACAGATGA CCTTTCTAGT
CCACCATCTG CACTTCCCAC CCCTCAGTTT GGTCAGAGGA CAACAAAATC CAAGAAGAAA
AAGGGACACA AGGGCAAAAA TTGTATTATT TCTTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001138354.1
CDS287..2782
Misc Feature(1)260..262(+)
Misc Feature(2)350..640(+)
Misc Feature(3)662..838(+)
Misc Feature(4)662..832(+)
Misc Feature(5)851..1018(+)
Misc Feature(6)857..1012(+)
Misc Feature(7)1031..1207(+)
Misc Feature(8)1037..1204(+)
Misc Feature(9)2768..2770(+)
Exon (1)1..238
Gene:PRICKLE1
Gene Synonym:
Exon (2)239..418
Gene:PRICKLE1
Gene Synonym:
Exon (3)419..532
Gene:PRICKLE1
Gene Synonym:
Exon (4)533..670
Gene:PRICKLE1
Gene Synonym:
Exon (5)671..874
Gene:PRICKLE1
Gene Synonym:
Exon (6)875..1061
Gene:PRICKLE1
Gene Synonym:
Exon (7)1062..1925
Gene:PRICKLE1
Gene Synonym:
Exon (8)1926..4253
Gene:PRICKLE1
Gene Synonym:
Translation
Position Chain Variation Link
10 10 a, g dbSNP:12322471
48 48 a, g dbSNP:145598574
68 68 a, g dbSNP:7315823
78 78 c, t dbSNP:188187954
91 91 g, t dbSNP:75377876
100 100 a, c dbSNP:140455644
106 106 a, g dbSNP:780074084
139 139 a, c dbSNP:56996689
227 227 a, g dbSNP:571399485
237 237 g, t dbSNP:534032095
245 245 c, t dbSNP:770613473
247 247 a, g dbSNP:370363439
254 254 a, g dbSNP:377567620
257 257 c, t dbSNP:755145462
259 259 a, g dbSNP:749324672
261 261 a, g dbSNP:780428375
265 265 a, g dbSNP:756354867
273 273 a, g dbSNP:200066556
274 274 c, g dbSNP:768032940
275 275 a, g dbSNP:373933563
276 276 a, c dbSNP:752163142
285 285 c, t dbSNP:186219547
294 294 -, t dbSNP:754532709
296 296 a, g dbSNP:762525821
298 298 a, g dbSNP:774935889
310 310 a, g dbSNP:764895665
311 311 a, g dbSNP:566073131
320 320 c, t dbSNP:752821879
323 323 a, g dbSNP:770828628
333 333 a, g dbSNP:746768839
334 334 c, t dbSNP:773216441
336 336 a, c dbSNP:771838146
346 346 a, c dbSNP:370960593
347 347 a, g dbSNP:780328472
385 385 c, t dbSNP:764986581
386 386 a, g, t dbSNP:781255236
387 387 c, t dbSNP:139176541
394 394 c, t dbSNP:147268650
399 399 -, c dbSNP:751319527
399 399 c, t dbSNP:145493619
400 400 a, g dbSNP:141743294
410 410 c, t dbSNP:758787019
411 411 c, t dbSNP:753183614
418 418 a, g dbSNP:377668062
427 427 c, g, t dbSNP:770054643
434 434 a, g dbSNP:745883137
437 437 c, t dbSNP:781477633
442 442 a, g dbSNP:771014475
447 447 a, g dbSNP:747418341
457 457 c, t dbSNP:778052349
460 460 g, t dbSNP:758734560
463 463 c, t dbSNP:144843013
467 467 a, g dbSNP:779382629
468 468 a, g dbSNP:754498750
469 469 c, t dbSNP:753221219
470 470 a, g dbSNP:140262447
474 474 c, t dbSNP:760293523
475 475 -, ccc dbSNP:779774332
475 475 c, t dbSNP:750059541
476 476 a, g dbSNP:767281272
486 486 a, g dbSNP:761685361
489 489 a, g dbSNP:774440655
492 492 c, t dbSNP:141795695
494 494 a, c dbSNP:759716073
529 529 -, t dbSNP:757924445
533 533 a, g dbSNP:764145941
535 535 a, g dbSNP:763029790
536 536 c, t dbSNP:775472022
537 537 a, g dbSNP:766439768
542 542 c, t dbSNP:112753281
564 564 a, g dbSNP:760798462
581 581 g, t dbSNP:773322867
596 596 c, t dbSNP:772217655
597 597 a, g dbSNP:113994140
604 604 a, g dbSNP:774649468
606 606 a, c dbSNP:201983132
608 608 a, g dbSNP:749826585
610 610 a, c dbSNP:143645243
631 631 a, g dbSNP:780596765
638 638 a, t dbSNP:755590703
647 647 c, g dbSNP:371720624
652 652 g, t dbSNP:745306550
656 656 a, g dbSNP:79087668
659 659 a, g dbSNP:756916881
660 660 c, t dbSNP:34837068
677 677 g, t dbSNP:35731866
685 685 a, c dbSNP:775864936
686 686 a, c dbSNP:200558941
692 692 a, c, g dbSNP:773739764
696 696 a, c dbSNP:533095698
708 708 g, t dbSNP:564918219
709 709 c, t dbSNP:746728526
712 712 c, t dbSNP:777559380
714 714 c, t dbSNP:758143303
717 717 a, g dbSNP:281865563
720 720 c, t dbSNP:765119777
721 721 a, g dbSNP:146650383
722 722 a, g dbSNP:753753811
723 723 g, t dbSNP:767649857
724 724 c, t dbSNP:761867849
731 731 a, g dbSNP:751791144
732 732 c, t dbSNP:528557291
733 733 a, g dbSNP:561240990
753 753 c, t dbSNP:775872848
755 755 a, g dbSNP:770028506
757 757 c, t dbSNP:201613485
765 765 c, t dbSNP:777277493
766 766 a, g dbSNP:376385820
776 776 c, g dbSNP:746462801
777 777 c, t dbSNP:777575981
795 795 a, g dbSNP:771717707
803 803 c, g dbSNP:747920863
807 807 a, g dbSNP:778817395
825 825 g, t dbSNP:754699794
835 835 c, t dbSNP:753829444
836 836 a, g dbSNP:765876974
839 839 g, t dbSNP:61924369
841 841 a, g dbSNP:779908231
844 844 g, t dbSNP:199650711
852 852 c, t dbSNP:751596896
859 859 c, t dbSNP:764241108
862 862 a, c dbSNP:763282675
865 865 a, c dbSNP:752826795
871 871 c, t dbSNP:74081707
872 872 a, g dbSNP:759969939
876 876 c, t dbSNP:542029566
898 898 a, c dbSNP:755994241
911 911 a, c, t dbSNP:777944504
912 912 a, g dbSNP:758400992
922 922 c, t dbSNP:753025298
923 923 a, c dbSNP:765322400
935 935 c, t dbSNP:772276749
944 944 a, g dbSNP:200263143
954 954 c, t dbSNP:754218148
955 955 a, g dbSNP:201394996
973 973 a, g dbSNP:761315405
975 975 a, g dbSNP:773561952
989 989 a, g dbSNP:375197568
992 992 c, t dbSNP:372213429
1000 1000 c, t dbSNP:368850875
1004 1004 c, t dbSNP:774058029
1006 1006 c, t dbSNP:374695088
1011 1011 -, g, gg dbSNP:148197048
1012 1012 g, t dbSNP:74918611
1016 1016 g, t dbSNP:775310173
1017 1017 a, t dbSNP:769543803
1022 1022 a, c dbSNP:745880716
1025 1025 c, t dbSNP:780974681
1030 1030 a, g dbSNP:34778200
1036 1036 c, t dbSNP:748113916
1044 1044 a, c dbSNP:779229187
1056 1056 a, g dbSNP:755578011
1073 1073 a, g dbSNP:775135171
1090 1090 c, t dbSNP:371149992
1091 1091 a, g dbSNP:376845777
1093 1093 a, g dbSNP:757752736
1094 1094 a, c dbSNP:752070986
1105 1105 c, t dbSNP:763656364
1106 1106 a, g dbSNP:762434475
1110 1110 c, t dbSNP:559947948
1111 1111 a, g dbSNP:368347802
1136 1136 c, t dbSNP:764805797
1140 1140 a, g dbSNP:759409673
1147 1147 c, t dbSNP:537302175
1162 1162 c, g dbSNP:776244004
1172 1172 a, g dbSNP:770740860
1192 1192 c, t dbSNP:759688762
1196 1196 a, g dbSNP:202205425
1200 1200 c, t dbSNP:375459191
1201 1201 a, g, t dbSNP:150052192
1203 1203 a, g dbSNP:768917442
1213 1213 g, t dbSNP:529793741
1220 1220 a, g dbSNP:780452958
1230 1230 c, g dbSNP:769860194
1240 1240 c, g, t dbSNP:139421676
1259 1259 c, g dbSNP:757632765
1263 1263 a, g dbSNP:752116352
1278 1278 a, g dbSNP:778192552
1290 1290 a, g dbSNP:757911190
1293 1293 c, g, t dbSNP:76029235
1302 1302 a, g dbSNP:764895755
1307 1307 c, t dbSNP:759164554
1308 1308 a, g dbSNP:577174749
1309 1309 a, c, g dbSNP:370013528
1310 1310 g, t dbSNP:773297758
1322 1322 c, t dbSNP:772094351
1336 1336 c, t dbSNP:141763288
1343 1343 c, t dbSNP:775761309
1345 1345 a, g dbSNP:769884613
1366 1366 c, t dbSNP:746139680
1372 1372 c, t dbSNP:781459043
1383 1383 a, g dbSNP:771210638
1389 1389 a, g dbSNP:747305137
1395 1395 a, c dbSNP:778286825
1421 1421 a, t dbSNP:758856895
1431 1431 a, g dbSNP:748636455
1432 1432 a, c dbSNP:778330311
1435 1435 a, g dbSNP:375407377
1442 1442 a, t dbSNP:754507423
1462 1462 c, t dbSNP:571386763
1488 1488 c, t dbSNP:766000495
1491 1491 c, t dbSNP:755979431
1494 1494 a, g dbSNP:367941464
1508 1508 c, g, t dbSNP:376384105
1511 1511 a, g dbSNP:774422189
1520 1520 a, g dbSNP:765287368
1524 1524 a, t dbSNP:759600108
1529 1529 a, g dbSNP:776720321
1533 1533 c, t dbSNP:151332996
1534 1534 a, g dbSNP:142502371
1553 1553 g, t dbSNP:773620209
1554 1554 a, g dbSNP:371689139
1565 1565 c, t dbSNP:553919252
1567 1567 c, t dbSNP:748722157
1568 1568 c, t dbSNP:779462876
1570 1570 c, t dbSNP:183742526
1584 1584 a, g dbSNP:748766846
1585 1585 a, t dbSNP:779594296
1595 1595 a, t dbSNP:755877569
1598 1598 c, g dbSNP:750068527
1613 1613 c, t dbSNP:767486612
1616 1616 a, c dbSNP:146199468
1619 1619 a, t dbSNP:751460514
1622 1622 c, g dbSNP:764022861
1627 1627 c, t dbSNP:759563559
1628 1628 a, t dbSNP:776727562
1631 1631 g, t dbSNP:766349772
1642 1642 a, g dbSNP:760931731
1644 1644 a, c dbSNP:773422113
1645 1645 c, g dbSNP:772484365
1646 1646 a, g dbSNP:748454609
1650 1650 c, t dbSNP:774727935
1658 1658 a, g dbSNP:769168031
1663 1663 c, t dbSNP:749735572
1672 1672 c, t dbSNP:779653619
1676 1676 a, c dbSNP:769424445
1677 1677 a, g dbSNP:138568653
1679 1679 a, g dbSNP:780931107
1689 1689 a, g dbSNP:556311726
1692 1692 c, g dbSNP:751326939
1698 1698 c, t dbSNP:777597253
1700 1700 c, t dbSNP:281865564
1703 1703 a, t dbSNP:538066196
1721 1721 a, g dbSNP:570770626
1724 1724 c, g dbSNP:552840971
1726 1726 c, g dbSNP:367822804
1729 1729 c, t dbSNP:376123082
1735 1735 c, t dbSNP:760731193
1747 1747 c, t dbSNP:116197349
1763 1763 a, c dbSNP:547914367
1767 1767 c, g dbSNP:560995986
1772 1772 a, c dbSNP:371789655
1774 1774 c, g dbSNP:762118167
1783 1783 a, g dbSNP:774825872
1791 1791 g, t dbSNP:768870075
1792 1792 a, g dbSNP:200460878
1797 1797 a, g dbSNP:201054946
1798 1798 c, t dbSNP:769438599
1803 1803 c, t dbSNP:745306755
1806 1806 c, t dbSNP:781019264
1827 1827 c, t dbSNP:374333566
1833 1833 c, g dbSNP:139901494
1845 1845 c, g dbSNP:777667268
1849 1849 a, g dbSNP:758126980
1853 1853 c, t dbSNP:150121787
1881 1881 a, g dbSNP:778765052
1887 1887 a, g dbSNP:756192425
1888 1888 a, g dbSNP:750464270
1889 1889 c, g dbSNP:371146879
1893 1893 c, t dbSNP:150766064
1894 1894 a, g dbSNP:144062651
1898 1898 g, t dbSNP:751724595
1899 1899 a, c dbSNP:764577468
1907 1907 g, t dbSNP:763169354
1909 1909 a, t dbSNP:776141626
1915 1915 a, c, t dbSNP:748556304
1918 1918 c, t dbSNP:776332277
1927 1927 a, g dbSNP:533432460
1932 1932 c, t dbSNP:370892022
1933 1933 a, c, g dbSNP:149518219
1934 1934 a, g dbSNP:760050261
1942 1942 a, t dbSNP:772922391
1962 1962 c, t dbSNP:771584708
1981 1981 g, t dbSNP:747960166
1997 1997 a, g dbSNP:774182139
1998 1998 c, t dbSNP:192905881
2033 2033 c, t dbSNP:138079613
2041 2041 c, t dbSNP:749279543
2054 2054 a, c, g dbSNP:757362404
2055 2055 a, g dbSNP:747016163
2058 2058 c, g dbSNP:778075325
2067 2067 a, c dbSNP:758594837
2072 2072 a, g dbSNP:752938677
2077 2077 g, t dbSNP:765766362
2079 2079 -, t dbSNP:776696757
2090 2090 g, t dbSNP:368664984
2103 2103 a, c dbSNP:754414301
2105 2105 a, t dbSNP:766728682
2119 2119 a, c, g dbSNP:749854195
2131 2131 a, t dbSNP:767033548
2142 2142 c, t dbSNP:761518408
2150 2150 c, t dbSNP:773978081
2151 2151 a, c dbSNP:768451748
2153 2153 a, g dbSNP:762668703
2155 2155 a, c, g dbSNP:150809651
2165 2165 a, c dbSNP:745792839
2174 2174 c, g dbSNP:200171609
2183 2183 -, tt dbSNP:111643910
2185 2185 c, t dbSNP:3747563
2188 2188 -, cc dbSNP:112291115
2188 2188 c, t dbSNP:3747562
2205 2205 a, g dbSNP:139937830
2208 2208 a, c, g dbSNP:374621616
2218 2218 c, t dbSNP:754215976
2219 2219 a, g dbSNP:780633961
2228 2228 c, g dbSNP:370129051
2238 2238 c, t dbSNP:750913400
2239 2239 c, g dbSNP:766992928
2249 2249 a, g dbSNP:557639324
2255 2255 c, g dbSNP:751217827
2261 2261 c, t dbSNP:376257338
2264 2264 a, g dbSNP:143947284
2268 2268 a, c dbSNP:775196409
2271 2271 a, g dbSNP:769599129
2272 2272 c, t dbSNP:759461345
2278 2278 a, g dbSNP:373302710
2283 2283 a, g dbSNP:370547490
2288 2288 a, t dbSNP:794727934
2297 2297 c, t dbSNP:776619006
2306 2306 c, t dbSNP:572205675
2307 2307 c, g dbSNP:748173327
2312 2312 c, t dbSNP:779314205
2313 2313 a, g dbSNP:377294908
2330 2330 c, t dbSNP:768954477
2331 2331 a, g dbSNP:189093086
2350 2350 c, t dbSNP:199893979
2357 2357 a, g dbSNP:149496604
2367 2367 a, g dbSNP:750904030
2375 2375 c, t dbSNP:781672373
2377 2377 c, t dbSNP:756787066
2390 2390 c, t dbSNP:751021008
2391 2391 a, g dbSNP:369790443
2394 2394 c, t dbSNP:758085094
2397 2397 a, t dbSNP:752387857
2400 2400 a, c dbSNP:765001355
2402 2402 c, t dbSNP:377228096
2404 2404 c, t dbSNP:374657704
2405 2405 a, g dbSNP:369077719
2408 2408 a, g dbSNP:371991440
2412 2412 a, g dbSNP:750226436
2414 2414 a, g dbSNP:774624657
2430 2430 a, g dbSNP:768827796
2431 2431 a, t dbSNP:749541698
2433 2433 a, g dbSNP:775721420
2440 2440 a, c dbSNP:770055515
2441 2441 c, t dbSNP:746199700
2442 2442 a, g dbSNP:779059953
2444 2444 a, g dbSNP:757810750
2455 2455 a, t dbSNP:757496174
2457 2457 a, t dbSNP:747481880
2475 2475 a, t dbSNP:777329767
2478 2478 a, g dbSNP:567656128
2479 2479 c, t dbSNP:137985321
2480 2480 a, g dbSNP:150287042
2488 2488 c, t dbSNP:570186739
2495 2495 a, g dbSNP:753625155
2502 2502 c, t dbSNP:138452760
2504 2504 g, t dbSNP:760738396
2508 2508 a, g dbSNP:375420597
2510 2510 a, g dbSNP:370967125
2522 2522 c, t dbSNP:3827522
2536 2536 a, g dbSNP:775601706
2548 2548 c, g dbSNP:727504104
2550 2550 -, ta dbSNP:768660106
2551 2551 c, t dbSNP:148989635
2552 2552 a, g dbSNP:777019107
2554 2554 c, t dbSNP:771279388
2555 2555 a, g dbSNP:145860632
2562 2562 a, g dbSNP:778196919
2564 2564 -, gat dbSNP:557205452
2569 2569 c, t dbSNP:149852787
2580 2580 c, t dbSNP:747655113
2587 2587 c, t dbSNP:778452934
2590 2590 -, ctc dbSNP:779393661
2590 2590 c, g dbSNP:35854729
2596 2596 c, t dbSNP:529575327
2597 2597 g, t dbSNP:146670726
2599 2599 c, t dbSNP:755963146
2602 2602 a, g dbSNP:143240342
2610 2610 -, aag dbSNP:758094682
2616 2616 a, g dbSNP:768039518
2622 2622 c, t dbSNP:374409698
2630 2630 c, t dbSNP:752866274
2645 2645 c, t dbSNP:765199745
2646 2646 a, g, t dbSNP:776819993
2649 2649 c, t dbSNP:200984524
2650 2650 a, g dbSNP:760964320
2653 2653 a, g dbSNP:549385436
2656 2656 a, g dbSNP:375310663
2666 2666 c, t dbSNP:201705679
2668 2668 c, t dbSNP:538043977
2671 2671 a, g dbSNP:748585713
2674 2674 c, t dbSNP:778528977
2675 2675 c, g dbSNP:746765797
2683 2683 c, t dbSNP:768050274
2686 2686 a, t dbSNP:139855191
2687 2687 c, t dbSNP:779783898
2690 2690 c, t dbSNP:150545495
2692 2692 a, g dbSNP:377290931
2698 2698 a, c dbSNP:750190848
2708 2708 a, c dbSNP:780823369
2711 2711 c, g dbSNP:142613488
2717 2717 a, g dbSNP:751446088
2720 2720 -, cagaggaca dbSNP:745483751
2725 2725 a, g dbSNP:138524511
2743 2743 a, g dbSNP:759552132
2748 2748 a, g dbSNP:754065513
2755 2755 c, t dbSNP:766549997
2773 2773 c, t dbSNP:376858650
2784 2784 c, t dbSNP:555008439
2785 2785 a, g dbSNP:567492165
2817 2817 a, g dbSNP:200644857
2827 2827 c, g, t dbSNP:372633476
2828 2828 a, g, t dbSNP:147122337
2837 2837 a, g dbSNP:560130870
2852 2852 a, g dbSNP:759888600
2857 2857 a, g dbSNP:542130236
2873 2873 c, t dbSNP:1043652
2885 2885 -, t dbSNP:151151770
2911 2911 a, g dbSNP:572315226
2991 2991 a, g dbSNP:192612214
3000 3000 c, t dbSNP:537460102
3010 3010 c, t dbSNP:576421272
3034 3034 a, c dbSNP:558237556
3043 3043 c, t dbSNP:1043656
3077 3077 -, at dbSNP:558821449
3077 3077 c, t dbSNP:761391791
3117 3117 a, g dbSNP:570071895
3148 3148 a, g dbSNP:547699182
3172 3172 c, g dbSNP:768200105
3180 3180 g, t dbSNP:17091220
3184 3184 g, t dbSNP:568438224
3189 3189 a, g, t dbSNP:745482621
3192 3192 c, t dbSNP:781107806
3212 3212 c, g dbSNP:141738298
3218 3218 c, g dbSNP:746977003
3219 3219 a, g dbSNP:777503447
3223 3223 a, c dbSNP:755082741
3230 3230 a, t dbSNP:571674666
3265 3265 a, c dbSNP:187632148
3274 3274 c, g dbSNP:563966550
3299 3299 c, t dbSNP:766425066
3309 3309 g, t dbSNP:12658
3310 3310 c, t dbSNP:750610528
3315 3315 c, t dbSNP:527422458
3324 3324 -, aa dbSNP:76259006
3324 3324 -, a dbSNP:398019285
3328 3328 a, c dbSNP:767986403
3333 3333 -, aa dbSNP:778238511
3334 3334 -, a dbSNP:756462439
3334 3334 -, a dbSNP:68074167
3334