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GSC goosecoid homeobox [Homo sapiens (human)]

Gene Symbol GSC
Entrez Gene ID 145258
Full Name goosecoid homeobox
Synonyms SAMS
General protein information
Preferred Names
homeobox protein goosecoid
Names
homeobox protein goosecoid
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q32.1

Summary This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

138890

Disorder Html:





The following GSC gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GSC gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu18704 NM_173849 Homo sapiens goosecoid homeobox (GSC), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$269

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu18704
Accession Version NM_173849.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 774bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu18704D_COA.pdf (pdf)
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product homeobox protein goosecoid
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY177407.1. This sequence is a reference standard in the RefSeqGene project. On Mar 25, 2003 this sequence version replaced gi:27777662. Summary: This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY177407.1, BC063580.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142680, SAMEA2154125 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCCCGCCA GCATGTTCAG CATCGACAAC ATCCTAGCCG CCCGGCCGCG CTGCAAGGAC 
TCGGTGTTGC CGGTGGCGCA CAGCGCGGCG GCTCCCGTCG TCTTCCCGGC CCTGCACGGG
GACTCGCTCT ACGGCGCCAG CGGCGGCGCC TCCTCGGACT ATGGCGCCTT CTACCCGCGC
CCCGTGGCCC CCGGCGGCGC GGGCCTCCCG GCCGCGGTCA GCGGCTCCCG CCTCGGCTAC
AACAACTACT TCTACGGGCA GCTGCACGTG CAGGCGGCGC CCGTGGGCCC GGCCTGCTGC
GGGGCCGTGC CGCCGCTGGG CGCCCAGCAG TGCTCCTGCG TCCCGACGCC CCCAGGCTAC
GAGGGCCCCG GTTCGGTGCT GGTGTCCCCG GTACCGCACC AGATGCTGCC CTACATGAAC
GTGGGCACGC TGTCGCGCAC CGAGCTGCAG CTTCTCAACC AGCTGCACTG TCGGCGGAAG
CGGCGGCACC GCACCATCTT CACTGACGAG CAGCTCGAAG CTCTCGAGAA CCTCTTCCAG
GAGACCAAGT ACCCGGACGT GGGCACGCGC GAGCAGCTGG CCCGGAAAGT GCACCTCCGC
GAGGAGAAAG TGGAGGTCTG GTTTAAGAAC CGCCGCGCCA AATGGAGGCG GCAGAAGCGG
TCCTCATCAG AGGAGTCGGA GAACGCGGAG AAGTGGAACA AGACGTCGTC GTCGAAGGCG
TCACCGGAGA AGAGGGAAGA GGAAGGTAAA AGCGATTTGG ACTCGGACAG CTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_776248.1
CDS148..921
Misc Feature(1)628..804(+)
Misc Feature(2)628..798(+)
Misc Feature(3)634..786(+)
Exon (1)1..502
Gene:GSC
Gene Synonym:
Exon (2)503..762
Gene:GSC
Gene Synonym:
Exon (3)763..1189
Gene:GSC
Gene Synonym:
Translation
Position Chain Variation Link
29 29 c, t dbSNP:533274562
78 78 -, c dbSNP:397940840
84 84 -, c dbSNP:57600257
84 84 c, t dbSNP:377469125
85 85 -, c dbSNP:570615381
98 98 c, t dbSNP:764449322
105 105 a, c, g dbSNP:752107422
115 115 c, t dbSNP:764852187
120 120 a, c, t dbSNP:776496067
121 121 c, t dbSNP:766136510
122 122 c, g, t dbSNP:183171414
125 125 a, c dbSNP:374459562
126 126 a, g, t dbSNP:748161636
130 130 c, t dbSNP:775407198
140 140 c, g dbSNP:769916000
143 143 c, g, t dbSNP:547578503
153 153 a, c dbSNP:529130661
158 158 a, g dbSNP:200899998
165 165 -, c dbSNP:34043238
165 165 c, t dbSNP:757483316
167 167 a, g dbSNP:747285885
170 170 c, t dbSNP:778230655
171 171 c, t dbSNP:758799355
176 176 a, g dbSNP:753305679
182 182 c, t dbSNP:764836563
210 210 c, g dbSNP:754473585
216 216 c, g dbSNP:753414164
222 222 c, g dbSNP:766083410
236 236 c, t dbSNP:760439922
237 237 a, g dbSNP:376492521
238 238 a, g dbSNP:767391192
241 241 c, t dbSNP:761638109
252 252 c, t dbSNP:774411319
255 255 a, g, t dbSNP:191352872
258 258 c, t dbSNP:776711989
265 265 c, g dbSNP:771101600
266 266 -, c dbSNP:34263175
283 283 a, g dbSNP:747295443
284 284 a, c dbSNP:777988148
290 290 a, g dbSNP:772555300
292 292 a, g dbSNP:531310446
295 295 -, gcg dbSNP:552249582
306 306 c, t dbSNP:370207480
308 308 a, c dbSNP:755567297
312 312 a, c dbSNP:753361195
321 321 c, t dbSNP:545878999
327 327 a, c dbSNP:755704451
337 337 c, t dbSNP:572177972
343 343 -, ggcgcgggcctcccggc dbSNP:587777288
360 360 c, t dbSNP:750144497
361 361 a, g dbSNP:145932252
370 370 c, g dbSNP:761600442
377 377 a, g dbSNP:751365495
381 381 c, g dbSNP:763969125
420 420 a, g dbSNP:541609162
428 428 c, t dbSNP:574191507
434 434 c, g dbSNP:776660853
453 453 a, c dbSNP:556011558
454 454 c, g dbSNP:771046649
508 508 a, g dbSNP:749863959
513 513 a, c dbSNP:779694045
514 514 c, t dbSNP:755714120
526 526 c, t dbSNP:765581983
538 538 g, t dbSNP:376420400
547 547 c, t dbSNP:587777289
558 558 c, g dbSNP:780836387
562 562 a, g dbSNP:756880471
563 563 c, t dbSNP:751314200
567 567 c, t dbSNP:144777037
570 570 c, g dbSNP:758309685
575 575 c, t dbSNP:752698866
584 584 a, g dbSNP:765091352
589 589 a, g dbSNP:527327953
597 597 a, c, g dbSNP:767740982
609 609 a, c, g, t dbSNP:149410963
610 610 c, t dbSNP:769205654
619 619 c, t dbSNP:765088049
636 636 c, t dbSNP:749804563
639 639 c, t dbSNP:776069902
642 642 c, t dbSNP:770212990
645 645 a, c dbSNP:745331419
672 672 c, g, t dbSNP:541597429
699 699 c, t dbSNP:117555620
702 702 a, g dbSNP:746712934
705 705 c, g dbSNP:777531321
706 706 g, t dbSNP:369844550
711 711 c, t dbSNP:758123549
712 712 a, g dbSNP:562169265
714 714 a, g dbSNP:765173607
718 718 a, c, g dbSNP:750487062
720 720 a, g dbSNP:543676956
732 732 c, g dbSNP:762116917
746 746 g, t dbSNP:774777528
753 753 c, g dbSNP:376810813
758 758 a, t dbSNP:763348360
778 778 -, c dbSNP:141452513
780 780 c, g dbSNP:771684088
800 800 a, c, g dbSNP:778759721
805 805 c, g dbSNP:768406079
819 819 a, g dbSNP:749109231
832 832 g, t dbSNP:543612146
834 834 a, g dbSNP:756139979
836 836 a, g dbSNP:751647283
839 839 a, g dbSNP:778037023
848 848 a, g dbSNP:758669591
852 852 c, g dbSNP:576276606
854 854 a, c, t dbSNP:759761613
859 859 -, tcg dbSNP:573100591
861 861 a, g dbSNP:368086868
867 867 a, g dbSNP:766832415
869 869 a, c dbSNP:761213502
870 870 a, g dbSNP:772688976
874 874 -, g dbSNP:750213730
882 882 a, g dbSNP:771631083
885 885 a, c, t dbSNP:773813335
888 888 a, g dbSNP:199891655
893 893 a, g dbSNP:748984329
901 901 g, t dbSNP:780023183
909 909 c, t dbSNP:769820637
912 912 a, g dbSNP:745848405
922 922 c, t dbSNP:777984980
927 927 a, g dbSNP:758616562
928 928 c, t dbSNP:748264067
929 929 g, t dbSNP:778953757
930 930 g, t dbSNP:755260260
932 932 a, g dbSNP:754123382
939 939 c, t dbSNP:766776988
940 940 c, t dbSNP:756597419
945 945 g, t dbSNP:371496658
969 969 a, c, g dbSNP:369236695
970 970 c, g dbSNP:773938542
976 976 c, t dbSNP:368987305
987 987 a, g dbSNP:546123232
996 996 a, c dbSNP:138867999
1012 1012 a, c dbSNP:377299455
1020 1020 a, g dbSNP:553893452
1023 1023 a, c dbSNP:747785381
1029 1029 a, g dbSNP:535902434
1036 1036 c, g dbSNP:574837156
1049 1049 a, g dbSNP:773905212
1064 1064 g, t dbSNP:556738745
1109 1109 c, t dbSNP:538026919
1160 1160 a, g dbSNP:768942419
1183 1183 c, t dbSNP:571023666
1184 1184 a, g dbSNP:377283111

Target ORF information:

RefSeq Version NM_173849
Organism Homo sapiens (human)
Definition Homo sapiens goosecoid homeobox (GSC), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_173849

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCCCGCCA GCATGTTCAG CATCGACAAC ATCCTAGCCG CCCGGCCGCG CTGCAAGGAC 
TCGGTGTTGC CGGTGGCGCA CAGCGCGGCG GCTCCCGTCG TCTTCCCGGC CCTGCACGGG
GACTCGCTCT ACGGCGCCAG CGGCGGCGCC TCCTCGGACT ATGGCGCCTT CTACCCGCGC
CCCGTGGCCC CCGGCGGCGC GGGCCTCCCG GCCGCGGTCA GCGGCTCCCG CCTCGGCTAC
AACAACTACT TCTACGGGCA GCTGCACGTG CAGGCGGCGC CCGTGGGCCC GGCCTGCTGC
GGGGCCGTGC CGCCGCTGGG CGCCCAGCAG TGCTCCTGCG TCCCGACGCC CCCAGGCTAC
GAGGGCCCCG GTTCGGTGCT GGTGTCCCCG GTACCGCACC AGATGCTGCC CTACATGAAC
GTGGGCACGC TGTCGCGCAC CGAGCTGCAG CTTCTCAACC AGCTGCACTG TCGGCGGAAG
CGGCGGCACC GCACCATCTT CACTGACGAG CAGCTCGAAG CTCTCGAGAA CCTCTTCCAG
GAGACCAAGT ACCCGGACGT GGGCACGCGC GAGCAGCTGG CCCGGAAAGT GCACCTCCGC
GAGGAGAAAG TGGAGGTCTG GTTTAAGAAC CGCCGCGCCA AATGGAGGCG GCAGAAGCGG
TCCTCATCAG AGGAGTCGGA GAACGCGGAG AAGTGGAACA AGACGTCGTC GTCGAAGGCG
TCACCGGAGA AGAGGGAAGA GGAAGGTAAA AGCGATTTGG ACTCGGACAG CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.