The following MESP2 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MESP2 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1194bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||mesoderm posterior protein 2
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BK000142.1 and AC079075.6.
This sequence is a reference standard in the RefSeqGene project.
On or before Mar 25, 2006 this sequence version replaced
Summary: This gene encodes a member of the bHLH family of
transcription factors and plays a key role in defining the
rostrocaudal patterning of somites via interactions with multiple
Notch signaling pathways. This gene is expressed in the anterior
presomitic mesoderm and is downregulated immediately after the
formation of segmented somites. This gene also plays a role in the
formation of epithelial somitic mesoderm and cardiac mesoderm.
Mutations in the MESP2 gene cause autosomal recessive
spondylocostal dystosis 2 (SCD02). [provided by RefSeq, Oct 2008].
Transcript exon combination :: BC111413.1, BQ431918.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns