The following CYP1A1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP1A1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||Documents for ORF clone product in dufault vector
||ORF Nucleotide Sequence (Length: 1539bp)
||pcDNA3.1+/C-(K)DYK or customized vector
||Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
||Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Document: OHu26754D_COA.pdf (pdf)
||Homo sapiens (human)
||cytochrome P450 1A1
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AC091230.23.
This sequence is a reference standard in the RefSeqGene project.
On Jun 4, 2008 this sequence version replaced gi:13325053.
Summary: This gene, CYP1A1, encodes a member of the cytochrome P450
superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug
metabolism and synthesis of cholesterol, steroids and other lipids.
This protein localizes to the endoplasmic reticulum and its
expression is induced by some polycyclic aromatic hydrocarbons
(PAHs), some of which are found in cigarette smoke. The enzyme's
endogenous substrate is unknown; however, it is able to metabolize
some PAHs to carcinogenic intermediates. The gene has been
associated with lung cancer risk. A related family member, CYP1A2,
is located approximately 25 kb away from CYP1A1 on chromosome 15.
[provided by RefSeq, Jul 2008].
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: K03191.1, AK223113.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: full length.