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CYP1A1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol CYP1A1
Entrez Gene ID 1543
Full Name cytochrome P450, family 1, subfamily A, polypeptide 1
Synonyms AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
General protein information
Preferred Names
cytochrome P450 1A1
Names
cytochrome P450 1A1
CYPIA1
cytochrome P450-C
cytochrome P450-P1
cytochrome P450 form 6
xenobiotic monooxygenase
aryl hydrocarbon hydroxylase
flavoprotein-linked monooxygenase
cytochrome P1-450, dioxin-inducible
cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1
NP_000490.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q24.1

Summary This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

108330


mRNA and Protein(s)

mRNA Protein Name
XM_005254185 XP_005254242 cytochrome P450 1A1 isoform X1
NM_000499 NP_000490 cytochrome P450 1A1



Homo sapiens (human) CYP1A1 NP_000490.1
Pan troglodytes (chimpanzee) LOC453744 XP_001137654.1
Macaca mulatta (Rhesus monkey) CYP1A1 NP_001035328.1
Canis lupus familiaris (dog) CYP1A1 XP_003433938.1
Bos taurus (cattle) CYP1A1 XP_005222075.1
Mus musculus (house mouse) Cyp1a1 NP_001129531.1
Rattus norvegicus (Norway rat) Cyp1a1 NP_036672.2
Gallus gallus (chicken) CYP1A1 NP_990477.1
Gallus gallus (chicken) CYP1A4 NP_990478.1
Danio rerio (zebrafish) cyp1a NP_571954.1
Arabidopsis thaliana (thale cress) CYP93D1 NP_196307.1
Xenopus (Silurana) tropicalis (western clawed frog) cyp1a1 NP_001090813.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CYP1A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP1A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu26754
XM_005254185 PREDICTED: Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
OHu26754
NM_000499 Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu26754
Clone ID Related Accession (Same CDS sequence) NM_000499 , XM_005254185
Accession Version XM_005254185.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1539bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product cytochrome P450 1A1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010194.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTCC CAATCTCCAT GTCGGCCACG GAGTTTCTTC TGGCCTCTGT CATCTTCTGT 
CTGGTATTCT GGGTAATCAG GGCCTCAAGA CCTCAGGTCC CCAAAGGCCT GAAGAATCCA
CCAGGGCCAT GGGGCTGGCC TCTGATTGGG CACATGCTGA CCCTGGGAAA GAACCCGCAC
CTGGCACTGT CAAGGATGAG CCAGCAGTAT GGGGACGTGC TGCAGATCCG AATTGGCTCC
ACACCCGTGG TGGTGCTGAG CGGCCTGGAC ACCATCCGGC AGGCCCTGGT GCGGCAGGGC
GATGATTTCA AGGGCCGGCC CGACCTCTAC ACCTTCACCC TCATCAGTAA TGGTCAGAGC
ATGTCCTTCA GCCCAGACTC TGGACCAGTG TGGGCTGCCC GCCGGCGCCT GGCCCAGAAT
GGCCTGAAAA GTTTCTCCAT TGCCTCTGAC CCAGCCTCCT CAACCTCCTG CTACCTGGAA
GAGCATGTGA GCAAGGAGGC TGAGGTCCTG ATAAGCACGT TGCAGGAGCT GATGGCAGGG
CCTGGGCACT TTAACCCCTA CAGGTATGTG GTGGTATCAG TGACCAATGT CATCTGTGCC
ATTTGCTTTG GCCGGCGCTA TGACCACAAC CACCAAGAAC TGCTTAGCCT AGTCAACCTG
AATAATAATT TCGGGGAGGT GGTTGGCTCT GGAAACCCAG CTGACTTCAT CCCTATTCTT
CGCTACCTAC CCAACCCTTC CCTGAATGCC TTCAAGGACC TGAATGAGAA GTTCTACAGC
TTCATGCAGA AGATGGTCAA GGAGCACTAC AAAACCTTTG AGAAGGGCCA CATCCGGGAC
ATCACAGACA GCCTGATTGA GCACTGTCAG GAGAAGCAGC TGGATGAGAA CGCCAATGTC
CAGCTGTCAG ATGAGAAGAT CATTAACATC GTCTTGGACC TCTTTGGAGC TGGGTTTGAC
ACAGTCACAA CTGCTATCTC CTGGAGCCTC ATGTATTTGG TGATGAACCC CAGGGTACAG
AGAAAGATCC AAGAGGAGCT AGACACAGTG ATTGGCAGGT CACGGCGGCC CCGGCTCTCT
GACAGATCCC ATCTGCCCTA TATGGAGGCC TTCATCCTGG AGACCTTCCG ACACTCTTCC
TTCGTCCCCT TCACCATCCC CCACAGCACA ACAAGAGACA CAAGTTTGAA AGGCTTTTAC
ATCCCCAAGG GGCGTTGTGT CTTTGTAAAC CAGTGGCAGA TCAACCATGA CCAGAAGCTA
TGGGTCAACC CATCTGAGTT CCTACCTGAA CGGTTTCTCA CCCCTGATGG TGCTATCGAC
AAGGTGTTAA GTGAGAAGGT GATTATCTTT GGCATGGGCA AGCGGAAGTG TATCGGTGAG
ACCATTGCCC GCTGGGAGGT CTTTCTCTTC CTGGCTATCC TGCTGCAACG GGTGGAATTC
AGCGTGCCAC TGGGCGTGAA GGTGGACATG ACCCCCATCT ATGGGCTAAC CATGAAGCAT
GCCTGCTGTG AGCACTTCCA AATGCAGCTG CGCTCTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005254242.1
CDS200..1738
Misc Feature(1)317..1678(+)
Translation

Target ORF information:

RefSeq Version XM_005254185
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005254185

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTCC CAATCTCCAT GTCGGCCACG GAGTTTCTTC TGGCCTCTGT CATCTTCTGT 
CTGGTATTCT GGGTAATCAG GGCCTCAAGA CCTCAGGTCC CCAAAGGCCT GAAGAATCCA
CCAGGGCCAT GGGGCTGGCC TCTGATTGGG CACATGCTGA CCCTGGGAAA GAACCCGCAC
CTGGCACTGT CAAGGATGAG CCAGCAGTAT GGGGACGTGC TGCAGATCCG AATTGGCTCC
ACACCCGTGG TGGTGCTGAG CGGCCTGGAC ACCATCCGGC AGGCCCTGGT GCGGCAGGGC
GATGATTTCA AGGGCCGGCC CGACCTCTAC ACCTTCACCC TCATCAGTAA TGGTCAGAGC
ATGTCCTTCA GCCCAGACTC TGGACCAGTG TGGGCTGCCC GCCGGCGCCT GGCCCAGAAT
GGCCTGAAAA GTTTCTCCAT TGCCTCTGAC CCAGCCTCCT CAACCTCCTG CTACCTGGAA
GAGCATGTGA GCAAGGAGGC TGAGGTCCTG ATAAGCACGT TGCAGGAGCT GATGGCAGGG
CCTGGGCACT TTAACCCCTA CAGGTATGTG GTGGTATCAG TGACCAATGT CATCTGTGCC
ATTTGCTTTG GCCGGCGCTA TGACCACAAC CACCAAGAAC TGCTTAGCCT AGTCAACCTG
AATAATAATT TCGGGGAGGT GGTTGGCTCT GGAAACCCAG CTGACTTCAT CCCTATTCTT
CGCTACCTAC CCAACCCTTC CCTGAATGCC TTCAAGGACC TGAATGAGAA GTTCTACAGC
TTCATGCAGA AGATGGTCAA GGAGCACTAC AAAACCTTTG AGAAGGGCCA CATCCGGGAC
ATCACAGACA GCCTGATTGA GCACTGTCAG GAGAAGCAGC TGGATGAGAA CGCCAATGTC
CAGCTGTCAG ATGAGAAGAT CATTAACATC GTCTTGGACC TCTTTGGAGC TGGGTTTGAC
ACAGTCACAA CTGCTATCTC CTGGAGCCTC ATGTATTTGG TGATGAACCC CAGGGTACAG
AGAAAGATCC AAGAGGAGCT AGACACAGTG ATTGGCAGGT CACGGCGGCC CCGGCTCTCT
GACAGATCCC ATCTGCCCTA TATGGAGGCC TTCATCCTGG AGACCTTCCG ACACTCTTCC
TTCGTCCCCT TCACCATCCC CCACAGCACA ACAAGAGACA CAAGTTTGAA AGGCTTTTAC
ATCCCCAAGG GGCGTTGTGT CTTTGTAAAC CAGTGGCAGA TCAACCATGA CCAGAAGCTA
TGGGTCAACC CATCTGAGTT CCTACCTGAA CGGTTTCTCA CCCCTGATGG TGCTATCGAC
AAGGTGTTAA GTGAGAAGGT GATTATCTTT GGCATGGGCA AGCGGAAGTG TATCGGTGAG
ACCATTGCCC GCTGGGAGGT CTTTCTCTTC CTGGCTATCC TGCTGCAACG GGTGGAATTC
AGCGTGCCAC TGGGCGTGAA GGTGGACATG ACCCCCATCT ATGGGCTAAC CATGAAGCAT
GCCTGCTGTG AGCACTTCCA AATGCAGCTG CGCTCTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26754
Clone ID Related Accession (Same CDS sequence) NM_000499 , XM_005254185
Accession Version NM_000499.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1539bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product cytochrome P450 1A1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC091230.23. This sequence is a reference standard in the RefSeqGene project. On Jun 4, 2008 this sequence version replaced gi:13325053. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: K03191.1, AK223113.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTCC CAATCTCCAT GTCGGCCACG GAGTTTCTTC TGGCCTCTGT CATCTTCTGT 
CTGGTATTCT GGGTAATCAG GGCCTCAAGA CCTCAGGTCC CCAAAGGCCT GAAGAATCCA
CCAGGGCCAT GGGGCTGGCC TCTGATTGGG CACATGCTGA CCCTGGGAAA GAACCCGCAC
CTGGCACTGT CAAGGATGAG CCAGCAGTAT GGGGACGTGC TGCAGATCCG AATTGGCTCC
ACACCCGTGG TGGTGCTGAG CGGCCTGGAC ACCATCCGGC AGGCCCTGGT GCGGCAGGGC
GATGATTTCA AGGGCCGGCC CGACCTCTAC ACCTTCACCC TCATCAGTAA TGGTCAGAGC
ATGTCCTTCA GCCCAGACTC TGGACCAGTG TGGGCTGCCC GCCGGCGCCT GGCCCAGAAT
GGCCTGAAAA GTTTCTCCAT TGCCTCTGAC CCAGCCTCCT CAACCTCCTG CTACCTGGAA
GAGCATGTGA GCAAGGAGGC TGAGGTCCTG ATAAGCACGT TGCAGGAGCT GATGGCAGGG
CCTGGGCACT TTAACCCCTA CAGGTATGTG GTGGTATCAG TGACCAATGT CATCTGTGCC
ATTTGCTTTG GCCGGCGCTA TGACCACAAC CACCAAGAAC TGCTTAGCCT AGTCAACCTG
AATAATAATT TCGGGGAGGT GGTTGGCTCT GGAAACCCAG CTGACTTCAT CCCTATTCTT
CGCTACCTAC CCAACCCTTC CCTGAATGCC TTCAAGGACC TGAATGAGAA GTTCTACAGC
TTCATGCAGA AGATGGTCAA GGAGCACTAC AAAACCTTTG AGAAGGGCCA CATCCGGGAC
ATCACAGACA GCCTGATTGA GCACTGTCAG GAGAAGCAGC TGGATGAGAA CGCCAATGTC
CAGCTGTCAG ATGAGAAGAT CATTAACATC GTCTTGGACC TCTTTGGAGC TGGGTTTGAC
ACAGTCACAA CTGCTATCTC CTGGAGCCTC ATGTATTTGG TGATGAACCC CAGGGTACAG
AGAAAGATCC AAGAGGAGCT AGACACAGTG ATTGGCAGGT CACGGCGGCC CCGGCTCTCT
GACAGATCCC ATCTGCCCTA TATGGAGGCC TTCATCCTGG AGACCTTCCG ACACTCTTCC
TTCGTCCCCT TCACCATCCC CCACAGCACA ACAAGAGACA CAAGTTTGAA AGGCTTTTAC
ATCCCCAAGG GGCGTTGTGT CTTTGTAAAC CAGTGGCAGA TCAACCATGA CCAGAAGCTA
TGGGTCAACC CATCTGAGTT CCTACCTGAA CGGTTTCTCA CCCCTGATGG TGCTATCGAC
AAGGTGTTAA GTGAGAAGGT GATTATCTTT GGCATGGGCA AGCGGAAGTG TATCGGTGAG
ACCATTGCCC GCTGGGAGGT CTTTCTCTTC CTGGCTATCC TGCTGCAACG GGTGGAATTC
AGCGTGCCAC TGGGCGTGAA GGTGGACATG ACCCCCATCT ATGGGCTAAC CATGAAGCAT
GCCTGCTGTG AGCACTTCCA AATGCAGCTG CGCTCTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000490.1
CDS123..1661
Misc Feature(1)240..1601(+)
Misc Feature(2)1200..1202(+)
Misc Feature(3)1491..1493(+)
Exon (1)1..96
Gene:CYP1A1
Gene Synonym:
Exon (2)97..947
Gene:CYP1A1
Gene Synonym:
Exon (3)948..1074
Gene:CYP1A1
Gene Synonym:
Exon (4)1075..1164
Gene:CYP1A1
Gene Synonym:
Exon (5)1165..1288
Gene:CYP1A1
Gene Synonym:
Exon (6)1289..1375
Gene:CYP1A1
Gene Synonym:
Exon (7)1376..2608
Gene:CYP1A1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000499
Organism Homo sapiens (human)
Definition Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000499

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTCC CAATCTCCAT GTCGGCCACG GAGTTTCTTC TGGCCTCTGT CATCTTCTGT 
CTGGTATTCT GGGTAATCAG GGCCTCAAGA CCTCAGGTCC CCAAAGGCCT GAAGAATCCA
CCAGGGCCAT GGGGCTGGCC TCTGATTGGG CACATGCTGA CCCTGGGAAA GAACCCGCAC
CTGGCACTGT CAAGGATGAG CCAGCAGTAT GGGGACGTGC TGCAGATCCG AATTGGCTCC
ACACCCGTGG TGGTGCTGAG CGGCCTGGAC ACCATCCGGC AGGCCCTGGT GCGGCAGGGC
GATGATTTCA AGGGCCGGCC CGACCTCTAC ACCTTCACCC TCATCAGTAA TGGTCAGAGC
ATGTCCTTCA GCCCAGACTC TGGACCAGTG TGGGCTGCCC GCCGGCGCCT GGCCCAGAAT
GGCCTGAAAA GTTTCTCCAT TGCCTCTGAC CCAGCCTCCT CAACCTCCTG CTACCTGGAA
GAGCATGTGA GCAAGGAGGC TGAGGTCCTG ATAAGCACGT TGCAGGAGCT GATGGCAGGG
CCTGGGCACT TTAACCCCTA CAGGTATGTG GTGGTATCAG TGACCAATGT CATCTGTGCC
ATTTGCTTTG GCCGGCGCTA TGACCACAAC CACCAAGAAC TGCTTAGCCT AGTCAACCTG
AATAATAATT TCGGGGAGGT GGTTGGCTCT GGAAACCCAG CTGACTTCAT CCCTATTCTT
CGCTACCTAC CCAACCCTTC CCTGAATGCC TTCAAGGACC TGAATGAGAA GTTCTACAGC
TTCATGCAGA AGATGGTCAA GGAGCACTAC AAAACCTTTG AGAAGGGCCA CATCCGGGAC
ATCACAGACA GCCTGATTGA GCACTGTCAG GAGAAGCAGC TGGATGAGAA CGCCAATGTC
CAGCTGTCAG ATGAGAAGAT CATTAACATC GTCTTGGACC TCTTTGGAGC TGGGTTTGAC
ACAGTCACAA CTGCTATCTC CTGGAGCCTC ATGTATTTGG TGATGAACCC CAGGGTACAG
AGAAAGATCC AAGAGGAGCT AGACACAGTG ATTGGCAGGT CACGGCGGCC CCGGCTCTCT
GACAGATCCC ATCTGCCCTA TATGGAGGCC TTCATCCTGG AGACCTTCCG ACACTCTTCC
TTCGTCCCCT TCACCATCCC CCACAGCACA ACAAGAGACA CAAGTTTGAA AGGCTTTTAC
ATCCCCAAGG GGCGTTGTGT CTTTGTAAAC CAGTGGCAGA TCAACCATGA CCAGAAGCTA
TGGGTCAACC CATCTGAGTT CCTACCTGAA CGGTTTCTCA CCCCTGATGG TGCTATCGAC
AAGGTGTTAA GTGAGAAGGT GATTATCTTT GGCATGGGCA AGCGGAAGTG TATCGGTGAG
ACCATTGCCC GCTGGGAGGT CTTTCTCTTC CTGGCTATCC TGCTGCAACG GGTGGAATTC
AGCGTGCCAC TGGGCGTGAA GGTGGACATG ACCCCCATCT ATGGGCTAAC CATGAAGCAT
GCCTGCTGTG AGCACTTCCA AATGCAGCTG CGCTCTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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