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CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 [Homo sapiens (human)]

Gene Symbol CYP1A1
Entrez Gene ID 1543
Full Name cytochrome P450, family 1, subfamily A, polypeptide 1
Synonyms AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
General protein information
Preferred Names
cytochrome P450 1A1
Names
cytochrome P450 1A1
CYPIA1
cytochrome P450-C
cytochrome P450-P1
cytochrome P450 form 6
xenobiotic monooxygenase
aryl hydrocarbon hydroxylase
flavoprotein-linked monooxygenase
cytochrome P1-450, dioxin-inducible
cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1
NP_000490.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q24.1

Summary This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

108330

Disorder Html:
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu26754 XM_005254185 PREDICTED: Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00
OHu26754 NM_000499 Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu26754D
Sequence Information ORF Nucleotide Sequence (Length: 1539bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product cytochrome P450 1A1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010194.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTCC CAATCTCCAT GTCGGCCACG GAGTTTCTTC TGGCCTCTGT CATCTTCTGT 
CTGGTATTCT GGGTAATCAG GGCCTCAAGA CCTCAGGTCC CCAAAGGCCT GAAGAATCCA
CCAGGGCCAT GGGGCTGGCC TCTGATTGGG CACATGCTGA CCCTGGGAAA GAACCCGCAC
CTGGCACTGT CAAGGATGAG CCAGCAGTAT GGGGACGTGC TGCAGATCCG AATTGGCTCC
ACACCCGTGG TGGTGCTGAG CGGCCTGGAC ACCATCCGGC AGGCCCTGGT GCGGCAGGGC
GATGATTTCA AGGGCCGGCC CGACCTCTAC ACCTTCACCC TCATCAGTAA TGGTCAGAGC
ATGTCCTTCA GCCCAGACTC TGGACCAGTG TGGGCTGCCC GCCGGCGCCT GGCCCAGAAT
GGCCTGAAAA GTTTCTCCAT TGCCTCTGAC CCAGCCTCCT CAACCTCCTG CTACCTGGAA
GAGCATGTGA GCAAGGAGGC TGAGGTCCTG ATAAGCACGT TGCAGGAGCT GATGGCAGGG
CCTGGGCACT TTAACCCCTA CAGGTATGTG GTGGTATCAG TGACCAATGT CATCTGTGCC
ATTTGCTTTG GCCGGCGCTA TGACCACAAC CACCAAGAAC TGCTTAGCCT AGTCAACCTG
AATAATAATT TCGGGGAGGT GGTTGGCTCT GGAAACCCAG CTGACTTCAT CCCTATTCTT
CGCTACCTAC CCAACCCTTC CCTGAATGCC TTCAAGGACC TGAATGAGAA GTTCTACAGC
TTCATGCAGA AGATGGTCAA GGAGCACTAC AAAACCTTTG AGAAGGGCCA CATCCGGGAC
ATCACAGACA GCCTGATTGA GCACTGTCAG GAGAAGCAGC TGGATGAGAA CGCCAATGTC
CAGCTGTCAG ATGAGAAGAT CATTAACATC GTCTTGGACC TCTTTGGAGC TGGGTTTGAC
ACAGTCACAA CTGCTATCTC CTGGAGCCTC ATGTATTTGG TGATGAACCC CAGGGTACAG
AGAAAGATCC AAGAGGAGCT AGACACAGTG ATTGGCAGGT CACGGCGGCC CCGGCTCTCT
GACAGATCCC ATCTGCCCTA TATGGAGGCC TTCATCCTGG AGACCTTCCG ACACTCTTCC
TTCGTCCCCT TCACCATCCC CCACAGCACA ACAAGAGACA CAAGTTTGAA AGGCTTTTAC
ATCCCCAAGG GGCGTTGTGT CTTTGTAAAC CAGTGGCAGA TCAACCATGA CCAGAAGCTA
TGGGTCAACC CATCTGAGTT CCTACCTGAA CGGTTTCTCA CCCCTGATGG TGCTATCGAC
AAGGTGTTAA GTGAGAAGGT GATTATCTTT GGCATGGGCA AGCGGAAGTG TATCGGTGAG
ACCATTGCCC GCTGGGAGGT CTTTCTCTTC CTGGCTATCC TGCTGCAACG GGTGGAATTC
AGCGTGCCAC TGGGCGTGAA GGTGGACATG ACCCCCATCT ATGGGCTAAC CATGAAGCAT
GCCTGCTGTG AGCACTTCCA AATGCAGCTG CGCTCTTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_005254242.1
CDS200..1738
Misc Feature(1)317..1678(+)
Translation
Position Chain Variation Link
9 9 a, t dbSNP:546191599
18 18 a, g dbSNP:111578048
22 22 a, g dbSNP:376595443
25 25 a, g dbSNP:534695233
80 80 c, t dbSNP:570421098
85 85 a, g dbSNP:552361034
135 135 a, c dbSNP:530681678
153 153 c, t dbSNP:577435886
175 175 c, t dbSNP:770299285
184 184 a, g dbSNP:746333343
211 211 a, c dbSNP:764836276
212 212 a, g dbSNP:757606619
213 213 a, t dbSNP:560039501
218 218 a, g dbSNP:777905948
219 219 c, t dbSNP:758562697
222 222 c, t dbSNP:148505285
223 223 a, g dbSNP:576805455
225 225 c, t dbSNP:755133321
228 228 c, t dbSNP:753812224
229 229 a, g dbSNP:184128730
250 250 c, t dbSNP:543414137
256 256 a, c dbSNP:750252519
257 257 c, t dbSNP:767145702
260 260 c, t dbSNP:761407107
269 269 c, t dbSNP:774097027
270 270 a, g dbSNP:375315082
271 271 a, g dbSNP:145924908
274 274 a, g dbSNP:548705429
279 279 a, g dbSNP:777119337
284 284 c, t dbSNP:771432878
296 296 a, g dbSNP:747317438
301 301 a, c dbSNP:778141626
310 310 a, g dbSNP:772526583
325 325 g, t dbSNP:748295448
328 328 a, g dbSNP:779251470
332 332 c, g dbSNP:755005663
333 333 a, g dbSNP:4646422
337 337 c, g dbSNP:780078658
339 339 a, c dbSNP:756138124
345 345 a, c, t dbSNP:565370983
347 347 a, g dbSNP:767189328
348 348 a, g dbSNP:761719283
349 349 a, g dbSNP:751160077
362 362 c, t dbSNP:763875538
370 370 g, t dbSNP:762383674
375 375 c, t dbSNP:149846182
376 376 a, g dbSNP:578251068
378 378 a, c dbSNP:761140013
380 380 c, g dbSNP:773817962
383 383 a, c, g dbSNP:143070677
395 395 a, g dbSNP:35035798
397 397 a, g dbSNP:778933231
399 399 a, g dbSNP:769009780
400 400 c, g dbSNP:749328902
404 404 c, t dbSNP:572138243
408 408 a, g dbSNP:112517897
412 412 a, g dbSNP:370225248
413 413 a, g dbSNP:376399672
415 415 a, c, t dbSNP:139919943
416 416 a, g dbSNP:373568981
423 423 a, c dbSNP:554072118
428 428 a, c, t dbSNP:371190271
432 432 c, t dbSNP:17861094
438 438 c, t dbSNP:373246855
439 439 c, t dbSNP:55864856
441 441 c, t dbSNP:138474634
443 443 c, t dbSNP:537005466
445 445 a, c, g, t dbSNP:112522537
446 446 a, g dbSNP:768956417
460 460 c, t dbSNP:749494772
461 461 a, g dbSNP:77425771
468 468 a, g dbSNP:769983960
470 470 a, c dbSNP:746029569
471 471 c, t dbSNP:780925747
476 476 c, t dbSNP:2229150
477 477 a, g, t dbSNP:45528935
479 479 c, t dbSNP:758238061
483 483 c, t dbSNP:373137650
484 484 a, c dbSNP:764934348
491 491 c, t dbSNP:754416936
492 492 a, g dbSNP:368952331
494 494 c, t dbSNP:767860316
496 496 c, g, t dbSNP:774756784
498 498 g, t dbSNP:764534349
499 499 c, t dbSNP:377233098
500 500 a, g dbSNP:141173079
506 506 g, t dbSNP:548096213
514 514 a, cc dbSNP:34045449
514 514 a, c dbSNP:745879982
515 515 -, c dbSNP:779460432
515 515 c, t dbSNP:776797048
516 516 a, g dbSNP:770734367
518 518 a, c dbSNP:372306597
520 520 c, t dbSNP:35267501
521 521 a, g, t dbSNP:78901429
522 522 a, c dbSNP:373368945
530 530 a, g dbSNP:778476792
532 532 c, t dbSNP:754678764
538 538 a, c dbSNP:753243590
542 542 a, g dbSNP:779581749
550 550 c, t dbSNP:375076919
552 552 a, g dbSNP:755633017
569 569 a, g dbSNP:752097572
575 575 a, g dbSNP:375219443
576 576 a, c dbSNP:763346193
577 577 c, g dbSNP:753126837
583 583 a, g dbSNP:149540202
584 584 c, t dbSNP:372197865
585 585 c, t dbSNP:776759251
586 586 a, g, t dbSNP:760732132
593 593 c, g dbSNP:35196245
600 600 a, g dbSNP:367709511
601 601 a, c dbSNP:747885985
602 602 c, t dbSNP:45442501
603 603 a, g dbSNP:768371517
605 605 c, t dbSNP:141291433
606 606 a, g dbSNP:202201538
629 629 a, c dbSNP:755649144
633 633 -, t dbSNP:751520023
642 642 c, t dbSNP:749960160
676 676 a, g dbSNP:778370057
677 677 a, g dbSNP:758997626
680 680 a, g dbSNP:368890165
681 681 a, c, g dbSNP:202221673
684 684 a, g dbSNP:754086281
685 685 c, t dbSNP:375895657
699 699 c, g dbSNP:372215528
712 712 a, c dbSNP:28399426
717 717 c, g, t dbSNP:28399427
718 718 a, g dbSNP:150427960
727 727 a, g dbSNP:768487487
729 729 c, t dbSNP:749108158
737 737 a, g dbSNP:775144476
739 739 -, g dbSNP:766480120
739 739 g, t dbSNP:201933340
754 754 a, c, g dbSNP:140459785
757 757 c, g dbSNP:780882190
760 760 c, t dbSNP:771452682
765 765 a, g dbSNP:756867720
766 766 c, t dbSNP:748643768
767 767 a, g dbSNP:748723967
772 772 a, g dbSNP:199985203
785 785 a, g dbSNP:151244239
786 786 a, g dbSNP:754164711
810 810 c, g, t dbSNP:142255433
812 812 c, t dbSNP:201182659
813 813 a, g dbSNP:199734551
815 815 a, c, t dbSNP:200600221
816 816 a, g dbSNP:371913955
818 818 g, t dbSNP:763947897
824 824 a, c dbSNP:148803099
830 830 c, t dbSNP:775173815
839 839 c, g dbSNP:577523247
841 841 g, t dbSNP:745487156
845 845 a, g, t dbSNP:146622566
856 856 a, c dbSNP:746521944
864 864 a, g dbSNP:779416051
866 866 -, aat dbSNP:762836718
871 871 c, t dbSNP:144413202
872 872 a, g, t dbSNP:373858916
875 875 -, g dbSNP:772813716
880 880 c, g dbSNP:370787995
897 897 a, c, g dbSNP:767797064
902 902 c, g dbSNP:757263296
903 903 a, c dbSNP:751608165
907 907 c, t dbSNP:764047305
910 910 c, t dbSNP:537091773
911 911 c, t dbSNP:61747605
920 920 c, t dbSNP:149687459
927 927 g, t dbSNP:759464355
932 932 a, g dbSNP:555078861
934 934 a, c dbSNP:770718854
935 935 c, t dbSNP:760213300
942 942 c, t dbSNP:374229319
945 945 a, t dbSNP:771648532
946 946 g, t dbSNP:749731774
950 950 g, t dbSNP:780666450
964 964 -, ctgaat dbSNP:765089792
964 964 a, t dbSNP:770136721
965 965 a, g dbSNP:746238922
968 968 -, aag dbSNP:764497837
982 982 a, c dbSNP:781336696
983 983 a, g dbSNP:757497550
991 991 c, g dbSNP:139496485
992 992 a, g dbSNP:150514993
993 993 g, t dbSNP:758554936
997 997 c, t dbSNP:752565232
1001 1001 a, g dbSNP:765333534
1004 1004 a, c dbSNP:759345870
1015 1015 c, t dbSNP:753707799
1022 1022 a, g dbSNP:766089505
1034 1034 c, g, t dbSNP:34260157
1035 1035 a, g dbSNP:766251992
1039 1039 c, t dbSNP:760572432
1040 1040 a, g dbSNP:750037230
1047 1047 -, a dbSNP:776374978
1050 1050 a, g dbSNP:755815189
1053 1053 c, t dbSNP:761173802
1056 1056 c, t dbSNP:4987133
1067 1067 c, t dbSNP:767529575
1070 1070 g, t dbSNP:765698121
1074 1074 a, c dbSNP:760009642
1078 1078 c, g dbSNP:369522545
1079 1079 -, c dbSNP:768134937
1090 1090 c, t dbSNP:759758088
1095 1095 a, g dbSNP:747475208
1099 1099 a, c dbSNP:147428559
1100 1100 c, t dbSNP:576054856
1103 1103 c, t dbSNP:748134388
1112 1112 a, g dbSNP:779103951
1117 1117 g, t dbSNP:755155099
1123 1123 -, t dbSNP:746582348
1126 1126 c, t dbSNP:368742906
1130 1130 a, g dbSNP:376586536
1137 1137 a, g dbSNP:755794714
1139 1139 c, t dbSNP:750248838
1141 1141 c, g dbSNP:767031764
1143 1143 g, t dbSNP:756969439
1149 1149 c, t dbSNP:751256789
1151 1151 a, g dbSNP:373178275
1152 1152 a, g dbSNP:745612512
1158 1158 a, g dbSNP:781013981
1162 1162 -, a dbSNP:779098736
1169 1169 a, g dbSNP:757053417
1170 1170 c, g dbSNP:751201537
1172 1172 g, t dbSNP:201691396
1175 1175 a, g dbSNP:757839494
1177 1177 a, c dbSNP:752218650
1179 1179 c, t dbSNP:369465868
1180 1180 -, ct dbSNP:771360204
1186 1186 c, g dbSNP:766754993
1192 1192 a, g, t dbSNP:56313657
1196 1196 c, t dbSNP:750941152
1200 1200 c, t dbSNP:767906777
1206 1206 a, g dbSNP:762331374
1225 1225 c, g, t dbSNP:199747074
1226 1226 a, c dbSNP:763080902
1231 1231 a, t dbSNP:775674343
1232 1232 g, t dbSNP:539280298
1234 1234 a, g dbSNP:745800803
1236 1236 a, g dbSNP:781050138
1243 1243 a, c dbSNP:766508885
1245 1245 -, ca dbSNP:756248191
1245 1245 c, t dbSNP:746759986
1248 1248 c, t dbSNP:777511101
1251 1251 c, t dbSNP:771902675
1256 1256 a, g dbSNP:747822093
1262 1262 a, c, t dbSNP:191792412
1263 1263 a, g dbSNP:753298761
1266 1266 a, g dbSNP:368650547
1267 1267 c, g dbSNP:757872883
1269 1269 c, t dbSNP:148341881
1271 1271 c, t dbSNP:371074476
1272 1272 a, g dbSNP:186168141
1284 1284 g, t dbSNP:200723875
1285 1285 a, t dbSNP:765383478
1287 1287 c, t dbSNP:759604228
1299 1299 a, g dbSNP:776598021
1301 1301 a, g dbSNP:766484540
1306 1306 c, g dbSNP:760582221
1311 1311 a, t dbSNP:375093189
1314 1314 g, t dbSNP:771849645
1317 1317 c, t dbSNP:747896348
1324 1324 c, t dbSNP:773994633
1328 1328 c, t dbSNP:768212140
1329 1329 a, g dbSNP:201174966
1337 1337 g, t dbSNP:779682021
1342 1342 a, c dbSNP:2856833
1343 1343 a, g dbSNP:201651069
1347 1347 a, c, t dbSNP:778494829
1355 1355 a, g dbSNP:367605080
1362 1362 a, c, g dbSNP:765452772
1366 1366 c, g dbSNP:748507253
1371 1371 -, caa dbSNP:752891625
1377 1377 a, c dbSNP:762064937
1380 1380 c, g dbSNP:779123202
1385 1385 g, t dbSNP:755427562
1393 1393 -, c dbSNP:781425756
1400 1400 a, c dbSNP:777186546
1409 1409 c, g dbSNP:539847382
1410 1410 a, g dbSNP:754054915
1413 1413 a, g dbSNP:56127934
1414 1414 c, t dbSNP:756125136
1415 1415 -, tgt dbSNP:758349216
1416 1416 a, g dbSNP:750520977
1424 1424 a, g dbSNP:769134905
1431 1431 a, c dbSNP:767446337
1433 1433 c, t dbSNP:377421606
1439 1439 a, g dbSNP:751567451
1440 1440 c, t dbSNP:201265044
1443 1443 a, c, t dbSNP:762876189
1454 1454 a, g dbSNP:138804663
1457 1457 c, t dbSNP:759235687
1462 1462 g, t dbSNP:578124762
1463 1463 a, g dbSNP:770339773
1465 1465 a, c dbSNP:760233196
1469 1469 a, c dbSNP:774658772
1470 1470 c, t dbSNP:769227467
1474 1474 -, t dbSNP:72547510
1480 1480 c, t dbSNP:375950006
1481 1481 -, c dbSNP:761704913
1481 1481 c, t dbSNP:780364499
1490 1490 c, t dbSNP:770191780
1491 1491 a, g dbSNP:746078945
1504 1504 -, t dbSNP:753423324
1514 1514 a, g dbSNP:781545021
1516 1516 c, t dbSNP:200091037
1517 1517 a, g, t dbSNP:145198866
1518 1518 a, t dbSNP:758445411
1521 1521 a, g dbSNP:752724213
1531 1531 c, t dbSNP:765104543
1538 1538 g, t dbSNP:754884581
1542 1542 a, c, t dbSNP:72547509
1544 1544 a, t dbSNP:760050326
1551 1551 g, t dbSNP:772810680
1555 1555 a, g dbSNP:767053022
1556 1556 c, g dbSNP:763427692
1561 1561 g, t dbSNP:369745647
1562 1562 c, t dbSNP:770140945
1563 1563 a, g dbSNP:180744198
1569 1569 a, g dbSNP:776659416
1570 1570 -, t dbSNP:561096394
1573 1573 c, t dbSNP:147033233
1574 1574 a, g dbSNP:371662141
1581 1581 -, ccat dbSNP:760328769
1581 1581 a, c, t dbSNP:1799814
1583 1583 a, c, g, t dbSNP:1048943
1584 1584 c, t dbSNP:752537968
1585 1585 c, t dbSNP:74465117
1586 1586 a, g, t dbSNP:141177861
1587 1587 c, g, t dbSNP:2278970
1589 1589 a, c, t dbSNP:41279188
1594 1594 -, ggaggtc dbSNP:774927292
1595 1595 a, g dbSNP:750089998
1604 1604 -, ctc dbSNP:771594072
1606 1606 c, t dbSNP:766998000
1607 1607 g, t dbSNP:36121583
1608 1608 a, t dbSNP:761381484
1612 1612 -, tt dbSNP:759921335
1613 1613 -, t dbSNP:774964712
1616 1616 -, atcctg dbSNP:771179629
1620 1620 c, t dbSNP:147634852
1624 1624 g, t dbSNP:529036977
1625 1625 c, g dbSNP:759771555
1627 1627 -, ac dbSNP:749717901
1628 1628 c, g, t dbSNP:56240201
1629 1629 a, g dbSNP:140680363
1631 1631 a, g dbSNP:771243368
1631 1631 -, g dbSNP:778135006
1633 1633 a, g dbSNP:747236230
1635 1635 a, t dbSNP:773629149
1643 1643 a, g dbSNP:28399429
1646 1646 c, t dbSNP:45500996
1654 1654 c, g, t dbSNP:766602533
1655 1655 a, g, t dbSNP:749223641
1659 1659 -, aggtgga dbSNP:770074882
1661 1661 a, g dbSNP:779876388
1667 1667 -, a dbSNP:748394285
1671 1671 a, c dbSNP:755919617
1672 1672 c, t dbSNP:45460597
1674 1674 c, g dbSNP:28399430
1680 1680 a, g dbSNP:367604147
1682 1682 g, t dbSNP:142388113
1692 1692 c, t dbSNP:765698057
1698 1698 a, t dbSNP:760061276
1699 1699 c, t dbSNP:754354567
1701 1701 c, t dbSNP:766755387
1707 1707 g, t dbSNP:760948792
1711 1711 a, g dbSNP:773506583
1718 1718 c, g dbSNP:772442747
1729 1729 g, t dbSNP:578153711
1730 1730 c, t dbSNP:148638069
1731 1731 a, g, t dbSNP:56343424
1735 1735 c, t dbSNP:779920114
1738 1738 a, g dbSNP:371424602
1739 1739 g, t dbSNP:373796629
1740 1740 g, t dbSNP:780775308
1748 1748 -, ag dbSNP:781368432
1749 1749 a, g dbSNP:756934290
1754 1754 a, g dbSNP:751256989
1758 1758 c, t dbSNP:777246027
1760 1760 a, t dbSNP:757907867
1763 1763 a, g dbSNP:754368306
1768 1768 a, g dbSNP:368793878
1770 1770 c, t dbSNP:766806209
1776 1776 a, g dbSNP:761048738
1786 1786 a, g dbSNP:750709351
1820 1820 a, g dbSNP:544523064
1823 1823 a, g dbSNP:2606346
1831 1831 c, t dbSNP:574165571
1920 1920 c, g dbSNP:145262175
1924 1924 c, t dbSNP:4986880
1956 1956 c, g dbSNP:762293224
1979 1979 c, g dbSNP:375879810
1985 1985 c, t dbSNP:776990450
2033 2033 a, g dbSNP:56403730
2057 2057 a, c dbSNP:567024721
2064 2064 a, t dbSNP:764372283
2081 2081 a, c, g dbSNP:4986881
2086 2086 c, t dbSNP:28399431
2097 2097 a, g dbSNP:4986882
2105 2105 a, g dbSNP:764160627
2116 2116 c, g dbSNP:760091169
2134 2134 a, g dbSNP:761197429
2142 2142 c, t dbSNP:550252006
2184 2184 a, g dbSNP:139156785
2196 2196 a, c dbSNP:568225625
2201 2201 a, t dbSNP:775927378
2204 2204 c, t dbSNP:35427048
2220 2220 c, g dbSNP:370921123
2259 2259 g, t dbSNP:528404953
2278 2278 g, t dbSNP:151188660
2281 2281 a, c dbSNP:142117193
2329 2329 c, t dbSNP:533364873
2333 2333 c, t dbSNP:1800031
2351 2351 a, g dbSNP:4986883
2361 2361 c, t dbSNP:4986884
2367 2367 a, g dbSNP:574181719
2389 2389 a, g dbSNP:555951865
2392 2392 -, c dbSNP:35228499
2398 2398 c, t dbSNP:145951947
2446 2446 c, g dbSNP:17861086
2447 2447 c, g dbSNP:377756240
2448 2448 g, t dbSNP:576754848
2451 2451 c, g dbSNP:28399432
2451 2451 c, g, t dbSNP:17861085
2452 2452 c, g dbSNP:368204973
2453 2453 -, g dbSNP:200937928
2471 2471 a, g dbSNP:772983461
2495 2495 c, t dbSNP:143987603
2517 2517 a, g dbSNP:771818681
2525 2525 a, g dbSNP:539092866
2549 2549 a, c dbSNP:17861084
2590 2590 c, t dbSNP:556665867
2594 2594 g, t dbSNP:185383134
2626 2626 a, g dbSNP:568027278
2656 2656 c, g dbSNP:28427336

Target ORF information:

RefSeq Version XM_005254185
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_005254185

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTCC CAATCTCCAT GTCGGCCACG GAGTTTCTTC TGGCCTCTGT CATCTTCTGT 
CTGGTATTCT GGGTAATCAG GGCCTCAAGA CCTCAGGTCC CCAAAGGCCT GAAGAATCCA
CCAGGGCCAT GGGGCTGGCC TCTGATTGGG CACATGCTGA CCCTGGGAAA GAACCCGCAC
CTGGCACTGT CAAGGATGAG CCAGCAGTAT GGGGACGTGC TGCAGATCCG AATTGGCTCC
ACACCCGTGG TGGTGCTGAG CGGCCTGGAC ACCATCCGGC AGGCCCTGGT GCGGCAGGGC
GATGATTTCA AGGGCCGGCC CGACCTCTAC ACCTTCACCC TCATCAGTAA TGGTCAGAGC
ATGTCCTTCA GCCCAGACTC TGGACCAGTG TGGGCTGCCC GCCGGCGCCT GGCCCAGAAT
GGCCTGAAAA GTTTCTCCAT TGCCTCTGAC CCAGCCTCCT CAACCTCCTG CTACCTGGAA
GAGCATGTGA GCAAGGAGGC TGAGGTCCTG ATAAGCACGT TGCAGGAGCT GATGGCAGGG
CCTGGGCACT TTAACCCCTA CAGGTATGTG GTGGTATCAG TGACCAATGT CATCTGTGCC
ATTTGCTTTG GCCGGCGCTA TGACCACAAC CACCAAGAAC TGCTTAGCCT AGTCAACCTG
AATAATAATT TCGGGGAGGT GGTTGGCTCT GGAAACCCAG CTGACTTCAT CCCTATTCTT
CGCTACCTAC CCAACCCTTC CCTGAATGCC TTCAAGGACC TGAATGAGAA GTTCTACAGC
TTCATGCAGA AGATGGTCAA GGAGCACTAC AAAACCTTTG AGAAGGGCCA CATCCGGGAC
ATCACAGACA GCCTGATTGA GCACTGTCAG GAGAAGCAGC TGGATGAGAA CGCCAATGTC
CAGCTGTCAG ATGAGAAGAT CATTAACATC GTCTTGGACC TCTTTGGAGC TGGGTTTGAC
ACAGTCACAA CTGCTATCTC CTGGAGCCTC ATGTATTTGG TGATGAACCC CAGGGTACAG
AGAAAGATCC AAGAGGAGCT AGACACAGTG ATTGGCAGGT CACGGCGGCC CCGGCTCTCT
GACAGATCCC ATCTGCCCTA TATGGAGGCC TTCATCCTGG AGACCTTCCG ACACTCTTCC
TTCGTCCCCT TCACCATCCC CCACAGCACA ACAAGAGACA CAAGTTTGAA AGGCTTTTAC
ATCCCCAAGG GGCGTTGTGT CTTTGTAAAC CAGTGGCAGA TCAACCATGA CCAGAAGCTA
TGGGTCAACC CATCTGAGTT CCTACCTGAA CGGTTTCTCA CCCCTGATGG TGCTATCGAC
AAGGTGTTAA GTGAGAAGGT GATTATCTTT GGCATGGGCA AGCGGAAGTG TATCGGTGAG
ACCATTGCCC GCTGGGAGGT CTTTCTCTTC CTGGCTATCC TGCTGCAACG GGTGGAATTC
AGCGTGCCAC TGGGCGTGAA GGTGGACATG ACCCCCATCT ATGGGCTAAC CATGAAGCAT
GCCTGCTGTG AGCACTTCCA AATGCAGCTG CGCTCTTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu26754D
Sequence Information ORF Nucleotide Sequence (Length: 1539bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product cytochrome P450 1A1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC091230.23. This sequence is a reference standard in the RefSeqGene project. On Jun 4, 2008 this sequence version replaced gi:13325053. Summary: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: K03191.1, AK223113.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTCC CAATCTCCAT GTCGGCCACG GAGTTTCTTC TGGCCTCTGT CATCTTCTGT 
CTGGTATTCT GGGTAATCAG GGCCTCAAGA CCTCAGGTCC CCAAAGGCCT GAAGAATCCA
CCAGGGCCAT GGGGCTGGCC TCTGATTGGG CACATGCTGA CCCTGGGAAA GAACCCGCAC
CTGGCACTGT CAAGGATGAG CCAGCAGTAT GGGGACGTGC TGCAGATCCG AATTGGCTCC
ACACCCGTGG TGGTGCTGAG CGGCCTGGAC ACCATCCGGC AGGCCCTGGT GCGGCAGGGC
GATGATTTCA AGGGCCGGCC CGACCTCTAC ACCTTCACCC TCATCAGTAA TGGTCAGAGC
ATGTCCTTCA GCCCAGACTC TGGACCAGTG TGGGCTGCCC GCCGGCGCCT GGCCCAGAAT
GGCCTGAAAA GTTTCTCCAT TGCCTCTGAC CCAGCCTCCT CAACCTCCTG CTACCTGGAA
GAGCATGTGA GCAAGGAGGC TGAGGTCCTG ATAAGCACGT TGCAGGAGCT GATGGCAGGG
CCTGGGCACT TTAACCCCTA CAGGTATGTG GTGGTATCAG TGACCAATGT CATCTGTGCC
ATTTGCTTTG GCCGGCGCTA TGACCACAAC CACCAAGAAC TGCTTAGCCT AGTCAACCTG
AATAATAATT TCGGGGAGGT GGTTGGCTCT GGAAACCCAG CTGACTTCAT CCCTATTCTT
CGCTACCTAC CCAACCCTTC CCTGAATGCC TTCAAGGACC TGAATGAGAA GTTCTACAGC
TTCATGCAGA AGATGGTCAA GGAGCACTAC AAAACCTTTG AGAAGGGCCA CATCCGGGAC
ATCACAGACA GCCTGATTGA GCACTGTCAG GAGAAGCAGC TGGATGAGAA CGCCAATGTC
CAGCTGTCAG ATGAGAAGAT CATTAACATC GTCTTGGACC TCTTTGGAGC TGGGTTTGAC
ACAGTCACAA CTGCTATCTC CTGGAGCCTC ATGTATTTGG TGATGAACCC CAGGGTACAG
AGAAAGATCC AAGAGGAGCT AGACACAGTG ATTGGCAGGT CACGGCGGCC CCGGCTCTCT
GACAGATCCC ATCTGCCCTA TATGGAGGCC TTCATCCTGG AGACCTTCCG ACACTCTTCC
TTCGTCCCCT TCACCATCCC CCACAGCACA ACAAGAGACA CAAGTTTGAA AGGCTTTTAC
ATCCCCAAGG GGCGTTGTGT CTTTGTAAAC CAGTGGCAGA TCAACCATGA CCAGAAGCTA
TGGGTCAACC CATCTGAGTT CCTACCTGAA CGGTTTCTCA CCCCTGATGG TGCTATCGAC
AAGGTGTTAA GTGAGAAGGT GATTATCTTT GGCATGGGCA AGCGGAAGTG TATCGGTGAG
ACCATTGCCC GCTGGGAGGT CTTTCTCTTC CTGGCTATCC TGCTGCAACG GGTGGAATTC
AGCGTGCCAC TGGGCGTGAA GGTGGACATG ACCCCCATCT ATGGGCTAAC CATGAAGCAT
GCCTGCTGTG AGCACTTCCA AATGCAGCTG CGCTCTTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_000490.1
CDS123..1661
Misc Feature(1)240..1601(+)
Misc Feature(2)1200..1202(+)
Misc Feature(3)1491..1493(+)
Exon (1)1..96
Gene:CYP1A1
Gene Synonym:
Exon (2)97..947
Gene:CYP1A1
Gene Synonym:
Exon (3)948..1074
Gene:CYP1A1
Gene Synonym:
Exon (4)1075..1164
Gene:CYP1A1
Gene Synonym:
Exon (5)1165..1288
Gene:CYP1A1
Gene Synonym:
Exon (6)1289..1375
Gene:CYP1A1
Gene Synonym:
Exon (7)1376..2608
Gene:CYP1A1
Gene Synonym:
Translation
Position Chain Variation Link
6 6 c, t dbSNP:570421098
11 11 a, g dbSNP:552361034
61 61 a, c dbSNP:530681678
79 79 c, t dbSNP:577435886
98 98 c, t dbSNP:770299285
107 107 a, g dbSNP:746333343
134 134 a, c dbSNP:764836276
135 135 a, g dbSNP:757606619
136 136 a, t dbSNP:560039501
141 141 a, g dbSNP:777905948
142 142 c, t dbSNP:758562697
145 145 c, t dbSNP:148505285
146 146 a, g dbSNP:576805455
148 148 c, t dbSNP:755133321
151 151 c, t dbSNP:753812224
152 152 a, g dbSNP:184128730
173 173 c, t dbSNP:543414137
179 179 a, c dbSNP:750252519
180 180 c, t dbSNP:767145702
183 183 c, t dbSNP:761407107
192 192 c, t dbSNP:774097027
193 193 a, g dbSNP:375315082
194 194 a, g dbSNP:145924908
197 197 a, g dbSNP:548705429
202 202 a, g dbSNP:777119337
207 207 c, t dbSNP:771432878
219 219 a, g dbSNP:747317438
224 224 a, c dbSNP:778141626
233 233 a, g dbSNP:772526583
248 248 g, t dbSNP:748295448
251 251 a, g dbSNP:779251470
255 255 c, g dbSNP:755005663
256 256 a, g dbSNP:4646422
260 260 c, g dbSNP:780078658
262 262 a, c dbSNP:756138124
268 268 a, c, t dbSNP:565370983
270 270 a, g dbSNP:767189328
271 271 a, g dbSNP:761719283
272 272 a, g dbSNP:751160077
285 285 c, t dbSNP:763875538
293 293 g, t dbSNP:762383674
298 298 c, t dbSNP:149846182
299 299 a, g dbSNP:578251068
301 301 a, c dbSNP:761140013
303 303 c, g dbSNP:773817962
306 306 a, c, g dbSNP:143070677
318 318 a, g dbSNP:35035798
320 320 a, g dbSNP:778933231
322 322 a, g dbSNP:769009780
323 323 c, g dbSNP:749328902
327 327 c, t dbSNP:572138243
331 331 a, g dbSNP:112517897
335 335 a, g dbSNP:370225248
336 336 a, g dbSNP:376399672
338 338 a, c, t dbSNP:139919943
339 339 a, g dbSNP:373568981
346 346 a, c dbSNP:554072118
351 351 a, c, t dbSNP:371190271
355 355 c, t dbSNP:17861094
361 361 c, t dbSNP:373246855
362 362 c, t dbSNP:55864856
364 364 c, t dbSNP:138474634
366 366 c, t dbSNP:537005466
368 368 a, c, g, t dbSNP:112522537
369 369 a, g dbSNP:768956417
383 383 c, t dbSNP:749494772
384 384 a, g dbSNP:77425771
391 391 a, g dbSNP:769983960
393 393 a, c dbSNP:746029569
394 394 c, t dbSNP:780925747
399 399 c, t dbSNP:2229150
400 400 a, g, t dbSNP:45528935
402 402 c, t dbSNP:758238061
406 406 c, t dbSNP:373137650
407 407 a, c dbSNP:764934348
414 414 c, t dbSNP:754416936
415 415 a, g dbSNP:368952331
417 417 c, t dbSNP:767860316
419 419 c, g, t dbSNP:774756784
421 421 g, t dbSNP:764534349
422 422 c, t dbSNP:377233098
423 423 a, g dbSNP:141173079
429 429 g, t dbSNP:548096213
437 437 a, cc dbSNP:34045449
437 437 a, c dbSNP:745879982
438 438 -, c dbSNP:779460432
438 438 c, t dbSNP:776797048
439 439 a, g dbSNP:770734367
441 441 a, c dbSNP:372306597
443 443 c, t dbSNP:35267501
444 444 a, g, t dbSNP:78901429
445 445 a, c dbSNP:373368945
453 453 a, g dbSNP:778476792
455 455 c, t dbSNP:754678764
461 461 a, c dbSNP:753243590
465 465 a, g dbSNP:779581749
473 473 c, t dbSNP:375076919
475 475 a, g dbSNP:755633017
492 492 a, g dbSNP:752097572
498 498 a, g dbSNP:375219443
499 499 a, c dbSNP:763346193
500 500 c, g dbSNP:753126837
506 506 a, g dbSNP:149540202
507 507 c, t dbSNP:372197865
508 508 c, t dbSNP:776759251
509 509 a, g, t dbSNP:760732132
516 516 c, g dbSNP:35196245
523 523 a, g dbSNP:367709511
524 524 a, c dbSNP:747885985
525 525 c, t dbSNP:45442501
526 526 a, g dbSNP:768371517
528 528 c, t dbSNP:141291433
529 529 a, g dbSNP:202201538
552 552 a, c dbSNP:755649144
556 556 -, t dbSNP:751520023
565 565 c, t dbSNP:749960160
599 599 a, g dbSNP:778370057
600 600 a, g dbSNP:758997626
603 603 a, g dbSNP:368890165
604 604 a, c, g dbSNP:202221673
607 607 a, g dbSNP:754086281
608 608 c, t dbSNP:375895657
622 622 c, g dbSNP:372215528
635 635 a, c dbSNP:28399426
640 640 c, g, t dbSNP:28399427
641 641 a, g dbSNP:150427960
650 650 a, g dbSNP:768487487
652 652 c, t dbSNP:749108158
660 660 a, g dbSNP:775144476
662 662 -, g dbSNP:766480120
662 662 g, t dbSNP:201933340
677 677 a, c, g dbSNP:140459785
680 680 c, g dbSNP:780882190
683 683 c, t dbSNP:771452682
688 688 a, g dbSNP:756867720
689 689 c, t dbSNP:748643768
690 690 a, g dbSNP:748723967
695 695 a, g dbSNP:199985203
708 708 a, g dbSNP:151244239
709 709 a, g dbSNP:754164711
733 733 c, g, t dbSNP:142255433
735 735 c, t dbSNP:201182659
736 736 a, g dbSNP:199734551
738 738 a, c, t dbSNP:200600221
739 739 a, g dbSNP:371913955
741 741 g, t dbSNP:763947897
747 747 a, c dbSNP:148803099
753 753 c, t dbSNP:775173815
762 762 c, g dbSNP:577523247
764 764 g, t dbSNP:745487156
768 768 a, g, t dbSNP:146622566
779 779 a, c dbSNP:746521944
787 787 a, g dbSNP:779416051
789 789 -, aat dbSNP:762836718
794 794 c, t dbSNP:144413202
795 795 a, g, t dbSNP:373858916
798 798 -, g dbSNP:772813716
803 803 c, g dbSNP:370787995
820 820 a, c, g dbSNP:767797064
825 825 c, g dbSNP:757263296
826 826 a, c dbSNP:751608165
830 830 c, t dbSNP:764047305
833 833 c, t dbSNP:537091773
834 834 c, t dbSNP:61747605
843 843 c, t dbSNP:149687459
850 850 g, t dbSNP:759464355
855 855 a, g dbSNP:555078861
857 857 a, c dbSNP:770718854
858 858 c, t dbSNP:760213300
865 865 c, t dbSNP:374229319
868 868 a, t dbSNP:771648532
869 869 g, t dbSNP:749731774
873 873 g, t dbSNP:780666450
887 887 -, ctgaat dbSNP:765089792
887 887 a, t dbSNP:770136721
888 888 a, g dbSNP:746238922
891 891 -, aag dbSNP:764497837
905 905 a, c dbSNP:781336696
906 906 a, g dbSNP:757497550
914 914 c, g dbSNP:139496485
915 915 a, g dbSNP:150514993
916 916 g, t dbSNP:758554936
920 920 c, t dbSNP:752565232
924 924 a, g dbSNP:765333534
927 927 a, c dbSNP:759345870
938 938 c, t dbSNP:753707799
945 945 a, g dbSNP:766089505
957 957 c, g, t dbSNP:34260157
958 958 a, g dbSNP:766251992
962 962 c, t dbSNP:760572432
963 963 a, g dbSNP:750037230
970 970 -, a dbSNP:776374978
973 973 a, g dbSNP:755815189
976 976 c, t dbSNP:761173802
979 979 c, t dbSNP:4987133
990 990 c, t dbSNP:767529575
993 993 g, t dbSNP:765698121
997 997 a, c dbSNP:760009642
1001 1001 c, g dbSNP:369522545
1002 1002 -, c dbSNP:768134937
1013 1013 c, t dbSNP:759758088
1018 1018 a, g dbSNP:747475208
1022 1022 a, c dbSNP:147428559
1023 1023 c, t dbSNP:576054856
1026 1026 c, t dbSNP:748134388
1035 1035 a, g dbSNP:779103951
1040 1040 g, t dbSNP:755155099
1046 1046 -, t dbSNP:746582348
1049 1049 c, t dbSNP:368742906
1053 1053 a, g dbSNP:376586536
1060 1060 a, g dbSNP:755794714
1062 1062 c, t dbSNP:750248838
1064 1064 c, g dbSNP:767031764
1066 1066 g, t dbSNP:756969439
1072 1072 c, t dbSNP:751256789
1074 1074 a, g dbSNP:373178275
1075 1075 a, g dbSNP:745612512
1081 1081 a, g dbSNP:781013981
1085 1085 -, a dbSNP:779098736
1092 1092 a, g dbSNP:757053417
1093 1093 c, g dbSNP:751201537
1095 1095 g, t dbSNP:201691396
1098 1098 a, g dbSNP:757839494
1100 1100 a, c dbSNP:752218650
1102 1102 c, t dbSNP:369465868
1103 1103 -, ct dbSNP:771360204
1109 1109 c, g dbSNP:766754993
1115 1115 a, g, t dbSNP:56313657
1119 1119 c, t dbSNP:750941152
1123 1123 c, t dbSNP:767906777
1129 1129 a, g dbSNP:762331374
1148 1148 c, g, t dbSNP:199747074
1149 1149 a, c dbSNP:763080902
1154 1154 a, t dbSNP:775674343
1155 1155 g, t dbSNP:539280298
1157 1157 a, g dbSNP:745800803
1159 1159 a, g dbSNP:781050138
1166 1166 a, c dbSNP:766508885
1168 1168 -, ca dbSNP:756248191
1168 1168 c, t dbSNP:746759986
1171 1171 c, t dbSNP:777511101
1174 1174 c, t dbSNP:771902675
1179 1179 a, g dbSNP:747822093
1185 1185 a, c, t dbSNP:191792412
1186 1186 a, g dbSNP:753298761
1189 1189 a, g dbSNP:368650547
1190 1190 c, g dbSNP:757872883
1192 1192 c, t dbSNP:148341881
1194 1194 c, t dbSNP:371074476
1195 1195 a, g dbSNP:186168141
1207 1207 g, t dbSNP:200723875
1208 1208 a, t dbSNP:765383478
1210 1210 c, t dbSNP:759604228
1222 1222 a, g dbSNP:776598021
1224 1224 a, g dbSNP:766484540
1229 1229 c, g dbSNP:760582221
1234 1234 a, t dbSNP:375093189
1237 1237 g, t dbSNP:771849645
1240 1240 c, t dbSNP:747896348
1247 1247 c, t dbSNP:773994633
1251 1251 c, t dbSNP:768212140
1252 1252 a, g dbSNP:201174966
1260 1260 g, t dbSNP:779682021
1265 1265 a, c dbSNP:2856833
1266 1266 a, g dbSNP:201651069
1270 1270 a, c, t dbSNP:778494829
1278 1278 a, g dbSNP:367605080
1285 1285 a, c, g dbSNP:765452772
1289 1289 c, g dbSNP:748507253
1294 1294 -, caa dbSNP:752891625
1300 1300 a, c dbSNP:762064937
1303 1303 c, g dbSNP:779123202
1308 1308 g, t dbSNP:755427562
1316 1316 -, c dbSNP:781425756
1323 1323 a, c dbSNP:777186546
1332 1332 c, g dbSNP:539847382
1333 1333 a, g dbSNP:754054915
1336 1336 a, g dbSNP:56127934
1337 1337 c, t dbSNP:756125136
1338 1338 -, tgt dbSNP:758349216
1339 1339 a, g dbSNP:750520977
1347 1347 a, g dbSNP:769134905
1354 1354 a, c dbSNP:767446337
1356 1356 c, t dbSNP:377421606
1362 1362 a, g dbSNP:751567451
1363 1363 c, t dbSNP:201265044
1366 1366 a, c, t dbSNP:762876189
1377 1377 a, g dbSNP:138804663
1380 1380 c, t dbSNP:759235687
1385 1385 g, t dbSNP:578124762
1386 1386 a, g dbSNP:770339773
1388 1388 a, c dbSNP:760233196
1392 1392 a, c dbSNP:774658772
1393 1393 c, t dbSNP:769227467
1397 1397 -, t dbSNP:72547510
1403 1403 c, t dbSNP:375950006
1404 1404 -, c dbSNP:761704913
1404 1404 c, t dbSNP:780364499
1413 1413 c, t dbSNP:770191780
1414 1414 a, g dbSNP:746078945
1427 1427 -, t dbSNP:753423324
1437 1437 a, g dbSNP:781545021
1439 1439 c, t dbSNP:200091037
1440 1440 a, g, t dbSNP:145198866
1441 1441 a, t dbSNP:758445411
1444 1444 a, g dbSNP:752724213
1454 1454 c, t dbSNP:765104543
1461 1461 g, t dbSNP:754884581
1465 1465 a, c, t dbSNP:72547509
1467 1467 a, t dbSNP:760050326
1474 1474 g, t dbSNP:772810680
1478 1478 a, g dbSNP:767053022
1479 1479 c, g dbSNP:763427692
1484 1484 g, t dbSNP:369745647
1485 1485 c, t dbSNP:770140945
1486 1486 a, g dbSNP:180744198
1492 1492 a, g dbSNP:776659416
1493 1493 -, t dbSNP:561096394
1496 1496 c, t dbSNP:147033233
1497 1497 a, g dbSNP:371662141
1504 1504 -, ccat dbSNP:760328769
1504 1504 a, c, t dbSNP:1799814
1506 1506 a, c, g, t dbSNP:1048943
1507 1507 c, t dbSNP:752537968
1508 1508 c, t dbSNP:74465117
1509 1509 a, g, t dbSNP:141177861
1510 1510 c, g, t dbSNP:2278970
1512 1512 a, c, t dbSNP:41279188
1517 1517 -, ggaggtc dbSNP:774927292
1518 1518 a, g dbSNP:750089998
1527 1527 -, ctc dbSNP:771594072
1529 1529 c, t dbSNP:766998000
1530 1530 g, t dbSNP:36121583
1531 1531 a, t dbSNP:761381484
1535 1535 -, tt dbSNP:759921335
1536 1536 -, t dbSNP:774964712
1539 1539 -, atcctg dbSNP:771179629
1543 1543 c, t dbSNP:147634852
1547 1547 g, t dbSNP:529036977
1548 1548 c, g dbSNP:759771555
1550 1550 -, ac dbSNP:749717901
1551 1551 c, g, t dbSNP:56240201
1552 1552 a, g dbSNP:140680363
1554 1554 a, g dbSNP:771243368
1554 1554 -, g dbSNP:778135006
1556 1556 a, g dbSNP:747236230
1558 1558 a, t dbSNP:773629149
1566 1566 a, g dbSNP:28399429
1569 1569 c, t dbSNP:45500996
1577 1577 c, g, t dbSNP:766602533
1578 1578 a, g, t dbSNP:749223641
1582 1582 -, aggtgga dbSNP:770074882
1584 1584 a, g dbSNP:779876388
1590 1590 -, a dbSNP:748394285
1594 1594 a, c dbSNP:755919617
1595 1595 c, t dbSNP:45460597
1597 1597 c, g dbSNP:28399430
1603 1603 a, g dbSNP:367604147
1605 1605 g, t dbSNP:142388113
1615 1615 c, t dbSNP:765698057
1621 1621 a, t dbSNP:760061276
1622 1622 c, t dbSNP:754354567
1624 1624 c, t dbSNP:766755387
1630 1630 g, t dbSNP:760948792
1634 1634 a, g dbSNP:773506583
1641 1641 c, g dbSNP:772442747
1652 1652 g, t dbSNP:578153711
1653 1653 c, t dbSNP:148638069
1654 1654 a, g, t dbSNP:56343424
1658 1658 c, t dbSNP:779920114
1661 1661 a, g dbSNP:371424602
1662 1662 g, t dbSNP:373796629
1663 1663 g, t dbSNP:780775308
1671 1671 -, ag dbSNP:781368432
1672 1672 a, g dbSNP:756934290
1677 1677 a, g dbSNP:751256989
1681 1681 c, t dbSNP:777246027
1683 1683 a, t dbSNP:757907867
1686 1686 a, g dbSNP:754368306
1691 1691 a, g dbSNP:368793878
1693 1693 c, t dbSNP:766806209
1699 1699 a, g dbSNP:761048738
1709 1709 a, g dbSNP:750709351
1743 1743 a, g dbSNP:544523064
1746 1746 a, g dbSNP:2606346
1754 1754 c, t dbSNP:574165571
1843 1843 c, g dbSNP:145262175
1847 1847 c, t dbSNP:4986880
1879 1879 c, g dbSNP:762293224
1902 1902 c, g dbSNP:375879810
1908 1908 c, t dbSNP:776990450
1956 1956 a, g dbSNP:56403730
1980 1980 a, c dbSNP:567024721
1987 1987 a, t dbSNP:764372283
2004 2004 a, c, g dbSNP:4986881
2009 2009 c, t dbSNP:28399431
2020 2020 a, g dbSNP:4986882
2028 2028 a, g dbSNP:764160627
2039 2039 c, g dbSNP:760091169
2057 2057 a, g dbSNP:761197429
2065 2065 c, t dbSNP:550252006
2107 2107 a, g dbSNP:139156785
2119 2119 a, c dbSNP:568225625
2124 2124 a, t dbSNP:775927378
2127 2127 c, t dbSNP:35427048
2143 2143 c, g dbSNP:370921123
2182 2182 g, t dbSNP:528404953
2201 2201 g, t dbSNP:151188660
2204 2204 a, c dbSNP:142117193
2252 2252 c, t dbSNP:533364873
2256 2256 c, t dbSNP:1800031
2274 2274 a, g dbSNP:4986883
2284 2284 c, t dbSNP:4986884
2290 2290 a, g dbSNP:574181719
2312 2312 a, g dbSNP:555951865
2315 2315 -, c dbSNP:35228499
2321 2321 c, t dbSNP:145951947
2369 2369 c, g dbSNP:17861086
2370 2370 c, g dbSNP:377756240
2371 2371 g, t dbSNP:576754848
2374 2374 c, g dbSNP:28399432
2374 2374 c, g, t dbSNP:17861085
2375 2375 c, g dbSNP:368204973
2376 2376 -, g dbSNP:200937928
2394 2394 a, g dbSNP:772983461
2418 2418 c, t dbSNP:143987603
2440 2440 a, g dbSNP:771818681
2448 2448 a, g dbSNP:539092866
2472 2472 a, c dbSNP:17861084
2513 2513 c, t dbSNP:556665867
2517 2517 g, t dbSNP:185383134
2549 2549 a, g dbSNP:568027278
2579 2579 c, g dbSNP:28427336

Target ORF information:

RefSeq Version NM_000499
Organism Homo sapiens (human)
Definition Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_000499

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTCC CAATCTCCAT GTCGGCCACG GAGTTTCTTC TGGCCTCTGT CATCTTCTGT 
CTGGTATTCT GGGTAATCAG GGCCTCAAGA CCTCAGGTCC CCAAAGGCCT GAAGAATCCA
CCAGGGCCAT GGGGCTGGCC TCTGATTGGG CACATGCTGA CCCTGGGAAA GAACCCGCAC
CTGGCACTGT CAAGGATGAG CCAGCAGTAT GGGGACGTGC TGCAGATCCG AATTGGCTCC
ACACCCGTGG TGGTGCTGAG CGGCCTGGAC ACCATCCGGC AGGCCCTGGT GCGGCAGGGC
GATGATTTCA AGGGCCGGCC CGACCTCTAC ACCTTCACCC TCATCAGTAA TGGTCAGAGC
ATGTCCTTCA GCCCAGACTC TGGACCAGTG TGGGCTGCCC GCCGGCGCCT GGCCCAGAAT
GGCCTGAAAA GTTTCTCCAT TGCCTCTGAC CCAGCCTCCT CAACCTCCTG CTACCTGGAA
GAGCATGTGA GCAAGGAGGC TGAGGTCCTG ATAAGCACGT TGCAGGAGCT GATGGCAGGG
CCTGGGCACT TTAACCCCTA CAGGTATGTG GTGGTATCAG TGACCAATGT CATCTGTGCC
ATTTGCTTTG GCCGGCGCTA TGACCACAAC CACCAAGAAC TGCTTAGCCT AGTCAACCTG
AATAATAATT TCGGGGAGGT GGTTGGCTCT GGAAACCCAG CTGACTTCAT CCCTATTCTT
CGCTACCTAC CCAACCCTTC CCTGAATGCC TTCAAGGACC TGAATGAGAA GTTCTACAGC
TTCATGCAGA AGATGGTCAA GGAGCACTAC AAAACCTTTG AGAAGGGCCA CATCCGGGAC
ATCACAGACA GCCTGATTGA GCACTGTCAG GAGAAGCAGC TGGATGAGAA CGCCAATGTC
CAGCTGTCAG ATGAGAAGAT CATTAACATC GTCTTGGACC TCTTTGGAGC TGGGTTTGAC
ACAGTCACAA CTGCTATCTC CTGGAGCCTC ATGTATTTGG TGATGAACCC CAGGGTACAG
AGAAAGATCC AAGAGGAGCT AGACACAGTG ATTGGCAGGT CACGGCGGCC CCGGCTCTCT
GACAGATCCC ATCTGCCCTA TATGGAGGCC TTCATCCTGG AGACCTTCCG ACACTCTTCC
TTCGTCCCCT TCACCATCCC CCACAGCACA ACAAGAGACA CAAGTTTGAA AGGCTTTTAC
ATCCCCAAGG GGCGTTGTGT CTTTGTAAAC CAGTGGCAGA TCAACCATGA CCAGAAGCTA
TGGGTCAACC CATCTGAGTT CCTACCTGAA CGGTTTCTCA CCCCTGATGG TGCTATCGAC
AAGGTGTTAA GTGAGAAGGT GATTATCTTT GGCATGGGCA AGCGGAAGTG TATCGGTGAG
ACCATTGCCC GCTGGGAGGT CTTTCTCTTC CTGGCTATCC TGCTGCAACG GGTGGAATTC
AGCGTGCCAC TGGGCGTGAA GGTGGACATG ACCCCCATCT ATGGGCTAAC CATGAAGCAT
GCCTGCTGTG AGCACTTCCA AATGCAGCTG CGCTCTTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.