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MAGEB6 melanoma antigen family B6 [Homo sapiens (human)]

Gene Symbol MAGEB6
Entrez Gene ID 158809
Full Name melanoma antigen family B6
Synonyms CT3.4, MAGE-B6, MAGEB6A
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp21.3

Summary This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is expressed in testis, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

300467

Disorder Html:





The following MAGEB6 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEB6 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19153 NM_173523 Homo sapiens melanoma antigen family B6 (MAGEB6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $319

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu19153
Accession Version NM_173523.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1224bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen B6
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK097561.1. This sequence is a reference standard in the RefSeqGene project. On Mar 28, 2003 this sequence version replaced gi:27734966. Summary: This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is expressed in testis, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]. ##Evidence-Data-START## Transcript exon combination :: BC067286.1, AK097561.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGCCTCGGG GTCACAAGAG TAAGCTCCGT ACCTGTGAGA AACGCCAAGA GACCAATGGT 
CAGCCACAGG GTCTCACGGG TCCCCAGGCC ACTGCAGAGA AGCAGGAAGA GTCCCACTCT
TCCTCATCCT CTTCTCGCGC TTGTCTGGGT GATTGTCGTA GGTCTTCTGA TGCCTCCATT
CCTCAGGAGT CTCAGGGAGT GTCACCCACT GGGTCTCCTG ATGCAGTTGT TTCATATTCA
AAATCCGATG TGGCTGCCAA CGGCCAAGAT GAGAAAAGTC CAAGCACCTC CCGTGATGCC
TCCGTTCCTC AGGAGTCTCA GGGAGCTTCA CCCACTGGCT CTCCTGATGC AGGTGTTTCA
GGCTCAAAAT ATGATGTGGC TGCCAACGGC CAAGATGAGA AAAGTCCAAG CACTTCCCAT
GATGTCTCCG TTCCTCAGGA GTCTCAGGGA GCTTCACCCA CTGGCTCGCC TGATGCAGGT
GTTTCAGGCT CAAAATATGA TGTGGCTGCC GAGGGTGAAG ATGAGGAAAG TGTAAGCGCC
TCACAGAAAG CCATCATTTT TAAGCGCTTA AGCAAAGATG CTGTAAAGAA GAAGGCGTGC
ACGTTGGCGC AATTCCTGCA GAAGAAGTTT GAGAAGAAAG AGTCCATTTT GAAGGCAGAC
ATGCTGAAGT GTGTCCGCAG AGAGTACAAG CCCTACTTCC CTCAGATCCT CAACAGAACC
TCCCAACATT TGGTGGTGGC CTTTGGCGTT GAATTGAAAG AAATGGATTC CAGCGGCGAG
TCCTACACCC TTGTCAGCAA GCTAGGCCTC CCCAGTGAAG GAATTCTGAG TGGTGATAAT
GCGCTGCCGA AGTCGGGTCT CCTGATGTCG CTCCTGGTTG TGATCTTCAT GAACGGCAAC
TGTGCCACTG AAGAGGAGGT CTGGGAGTTC CTGGGTCTGT TGGGGATATA TGATGGGATC
CTGCATTCAA TCTATGGGGA TGCTCGGAAG ATCATTACTG AAGATTTGGT GCAAGATAAG
TACGTGGTTT ACCGGCAGGT GTGCAACAGT GATCCTCCAT GCTATGAGTT CCTGTGGGGT
CCACGAGCCT ATGCTGAAAC CACCAAGATG AGAGTCCTGC GTGTTTTGGC CGACAGCAGT
AACACCAGTC CCGGTTTATA CCCACATCTG TATGAAGACG CTTTGATAGA TGAGGTAGAG
AGAGCATTGA GACTGAGAGC TTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_775794.2
CDS150..1373
Misc Feature(1)102..104(+)
Misc Feature(2)156..440(+)
Misc Feature(3)753..1265(+)
Exon (1)1..88
Gene:MAGEB6
Gene Synonym:
Exon (2)89..1949
Gene:MAGEB6
Gene Synonym:
Translation
Position Chain Variation Link
3 3 a, t dbSNP:190809755
19 19 a, c, g dbSNP:138795824
30 30 c, t dbSNP:11795624
34 34 -, aaa dbSNP:754874727
74 74 a, t dbSNP:756868338
96 96 c, t dbSNP:776030301
99 99 c, t dbSNP:753723773
100 100 c, t dbSNP:770666850
121 121 -, c dbSNP:769300202
123 123 a, g, t dbSNP:367642623
129 129 c, g dbSNP:747265182
145 145 c, t dbSNP:768692379
148 148 c, t dbSNP:781314424
149 149 c, t dbSNP:200391427
157 157 a, g dbSNP:770333290
158 158 c, g, t dbSNP:765228472
160 160 g, t dbSNP:139871286
161 161 a, t dbSNP:145353149
169 169 a, g dbSNP:774513630
173 173 c, g dbSNP:377232157
178 178 a, g dbSNP:201048484
179 179 c, t dbSNP:759303415
181 181 c, t dbSNP:767268005
192 192 c, t dbSNP:775192724
193 193 a, g dbSNP:750398271
205 205 a, g dbSNP:147683466
206 206 c, t dbSNP:753831889
207 207 a, g dbSNP:199633839
219 219 a, g dbSNP:142452268
222 222 c, t dbSNP:142389522
251 251 a, g dbSNP:201563340
256 256 a, c dbSNP:181053383
260 260 c, g, t dbSNP:151294955
261 261 c, t dbSNP:376205420
268 268 c, g dbSNP:749807793
271 271 a, c dbSNP:771341202
272 272 c, t dbSNP:774839904
274 274 c, t dbSNP:746200583
277 277 c, t dbSNP:771894329
285 285 c, t dbSNP:775309752
287 287 c, t dbSNP:112103680
288 288 a, g dbSNP:369371623
292 292 c, g dbSNP:372794202
297 297 c, g dbSNP:761876277
305 305 c, t dbSNP:765070672
306 306 c, t dbSNP:750281330
307 307 a, g dbSNP:375799757
317 317 c, t dbSNP:766113885
326 326 c, t dbSNP:752929934
336 336 a, g dbSNP:754646470
348 348 a, g dbSNP:756264135
349 349 c, t dbSNP:765128085
350 350 g, t dbSNP:752712953
355 355 c, g dbSNP:777977209
358 358 c, t dbSNP:749317847
361 361 a, g dbSNP:757834889
362 362 c, g dbSNP:758220941
363 363 a, t dbSNP:779260937
364 364 a, c dbSNP:746350570
372 372 a, g dbSNP:772583685
376 376 g, t dbSNP:778016322
392 392 a, g dbSNP:150480550
393 393 a, t dbSNP:746661233
394 394 c, t dbSNP:138482118
396 396 a, c, g, t dbSNP:776261244
398 398 c, t dbSNP:773054394
399 399 -, gtggctgcc dbSNP:774808021
400 400 c, t dbSNP:780763243
407 407 c, t dbSNP:762819989
410 410 c, t dbSNP:766167073
411 411 a, g dbSNP:140212002
415 415 a, g dbSNP:760948138
417 417 g, t dbSNP:764202252
428 428 g, t dbSNP:141073823
429 429 c, t dbSNP:757316619
430 430 a, c, g, t dbSNP:137921004
432 432 a, g dbSNP:780628745
433 433 c, g dbSNP:747363963
434 434 c, t dbSNP:768401582
437 437 c, t dbSNP:4351548
441 441 c, t dbSNP:769254324
442 442 a, g dbSNP:4630029
448 448 c, t dbSNP:4272533
451 451 a, c, t dbSNP:200942471
452 452 c, t dbSNP:148243334
453 453 a, g dbSNP:201693952
462 462 a, g dbSNP:772712644
469 469 a, g dbSNP:776031015
480 480 a, c dbSNP:141294776
485 485 c, t dbSNP:774183960
488 488 c, g, t dbSNP:772774443
490 490 a, c dbSNP:767307552
491 491 g, t dbSNP:4997767
494 494 c, t dbSNP:754033718
501 501 a, g dbSNP:147419502
502 502 c, g, t dbSNP:192410901
509 509 a, c dbSNP:750523959
510 510 g, t dbSNP:201187777
511 511 a, g dbSNP:139779543
514 514 c, t dbSNP:759030072
520 520 a, c dbSNP:143802048
521 521 c, t dbSNP:373452617
525 525 a, g dbSNP:376873999
529 529 c, g, t dbSNP:201644419
530 530 g, t dbSNP:781571372
536 536 c, t dbSNP:183964860
537 537 a, g dbSNP:747759841
538 538 a, g dbSNP:755787849
549 549 a, g dbSNP:777323599
552 552 a, t dbSNP:748775661
555 555 a, c dbSNP:770899085
565 565 c, t dbSNP:774306818
566 566 c, t dbSNP:745774251
569 569 c, t dbSNP:147251655
574 574 c, t dbSNP:757394019
577 577 c, t dbSNP:775285937
578 578 c, t dbSNP:762005644
579 579 a, g dbSNP:79139553
582 582 c, t dbSNP:773473561
590 590 a, g dbSNP:371259737
595 595 a, g dbSNP:750676452
596 596 a, g dbSNP:752135139
597 597 c, g dbSNP:755446278
608 608 c, t dbSNP:374192441
613 613 c, g dbSNP:73499811
616 616 c, t dbSNP:368279847
617 617 a, g, t dbSNP:777376582
622 622 a, t dbSNP:756785144
636 636 a, g dbSNP:778340145
653 653 a, g dbSNP:745794101
658 658 a, c, g dbSNP:772038632
659 659 c, t dbSNP:746794376
660 660 a, g, t dbSNP:770179071
663 663 c, g dbSNP:145782491
667 667 a, g dbSNP:201123921
671 671 c, t dbSNP:774569084
674 674 a, c, g dbSNP:760019719
685 685 a, g dbSNP:755535839
686 686 c, t dbSNP:148547775
687 687 a, g dbSNP:576906199
696 696 a, g dbSNP:753506759
702 702 a, c dbSNP:756831980
714 714 c, t dbSNP:142927857
715 715 a, g dbSNP:749932015
717 717 c, t dbSNP:146625385
740 740 c, g dbSNP:780007545
746 746 a, g dbSNP:370599063
751 751 c, t dbSNP:768592764
752 752 a, g dbSNP:375231005
758 758 a, g dbSNP:749588986
760 760 a, t dbSNP:28416260
764 764 c, t dbSNP:367835358
767 767 a, g dbSNP:774344871
771 771 a, g dbSNP:759632498
777 777 a, t dbSNP:772007637
788 788 a, g dbSNP:776089599
792 792 c, t dbSNP:761115892
802 802 a, t dbSNP:764451802
805 805 c, t dbSNP:754193959
810 810 a, g dbSNP:761508094
818 818 c, g dbSNP:141448892
820 820 a, g dbSNP:749939098
822 822 c, g dbSNP:776070636
825 825 c, t dbSNP:200923993
826 826 a, g dbSNP:187176082
827 827 c, t dbSNP:145176449
829 829 a, g, t dbSNP:201604663
839 839 a, g dbSNP:775425014
854 854 c, g dbSNP:771319980
870 870 g, t dbSNP:779229056
871 871 c, t dbSNP:746031016
878 878 g, t dbSNP:201952857
890 890 a, c dbSNP:772210349
893 893 c, t dbSNP:375291505
897 897 a, g dbSNP:775370255
905 905 c, g, t dbSNP:774457033
913 913 c, t dbSNP:761789720
915 915 g, t dbSNP:762131956
916 916 a, g dbSNP:765476547
923 923 c, t dbSNP:143373947
924 924 a, g dbSNP:762453651
926 926 c, t dbSNP:765918379
935 935 c, t dbSNP:371455211
938 938 c, t dbSNP:377252536
946 946 a, g dbSNP:755016136
949 949 a, t dbSNP:767531922
957 957 c, t dbSNP:140743739
968 968 a, g dbSNP:755997966
972 972 a, g dbSNP:777377029
973 973 g, t dbSNP:746104339
974 974 a, t dbSNP:758540322
976 976 c, t dbSNP:780241589
977 977 c, g dbSNP:747072456
979 979 a, g dbSNP:201763501
988 988 a, g dbSNP:777156029
990 990 g, t dbSNP:748607732
991 991 c, t dbSNP:200287901
992 992 a, g dbSNP:773382413
997 997 c, t dbSNP:750400525
1002 1002 a, t dbSNP:765925961
1003 1003 c, t dbSNP:774043480
1004 1004 a, g dbSNP:756424439
1013 1013 a, g dbSNP:767084349
1018 1018 c, t dbSNP:752693125
1020 1020 a, c dbSNP:375654499
1026 1026 c, g dbSNP:764012561
1027 1027 g, t dbSNP:753566928
1029 1029 g, t dbSNP:758698861
1043 1043 c, t dbSNP:200964551
1044 1044 a, g, t dbSNP:747194970
1051 1051 a, g dbSNP:781192763
1080 1080 c, t dbSNP:138463453
1088 1088 c, g dbSNP:149287704
1105 1105 a, g dbSNP:773675055
1124 1124 c, t dbSNP:749584403
1135 1135 a, g dbSNP:771286398
1142 1142 c, g dbSNP:754278277
1148 1148 a, t dbSNP:759204900
1155 1155 a, t dbSNP:767137294
1172 1172 c, t dbSNP:146988382
1183 1183 a, g dbSNP:760719328
1189 1189 g, t dbSNP:200442849
1191 1191 g, t dbSNP:753710312
1195 1195 a, g dbSNP:761547798
1197 1197 a, g dbSNP:764965014
1209 1209 c, t dbSNP:751795096
1210 1210 c, g dbSNP:755127770
1213 1213 a, t dbSNP:781316600
1241 1241 c, t dbSNP:752706201
1263 1263 c, g dbSNP:756684675
1268 1268 a, g dbSNP:778172988
1269 1269 c, t dbSNP:369750377
1270 1270 a, g dbSNP:771212245
1277 1277 a, g dbSNP:779351198
1280 1280 c, t dbSNP:138180623
1281 1281 a, g dbSNP:371772454
1287 1287 a, g dbSNP:775184641
1294 1294 c, t dbSNP:760076681
1297 1297 c, g dbSNP:768174782
1300 1300 c, t dbSNP:374854219
1301 1301 c, t dbSNP:143709838
1302 1302 a, g dbSNP:192290000
1311 1311 c, t dbSNP:147228278
1328 1328 c, t dbSNP:759811799
1336 1336 c, t dbSNP:148714935
1340 1340 c, t dbSNP:752923301
1341 1341 a, g dbSNP:756169501
1343 1343 a, g dbSNP:777849369
1347 1347 a, g dbSNP:754303361
1349 1349 a, g dbSNP:141440461
1356 1356 c, t dbSNP:779474748
1361 1361 a, g dbSNP:150840438
1364 1364 a, g dbSNP:771894400
1366 1366 c, g dbSNP:779888106
1369 1369 c, t dbSNP:746626829
1371 1371 g, t dbSNP:758846703
1376 1376 c, t dbSNP:776142567
1386 1386 a, g dbSNP:368976248
1389 1389 a, g dbSNP:769706307
1392 1392 c, t dbSNP:773041104
1393 1393 a, c dbSNP:745367786
1398 1398 g, t dbSNP:769550388
1405 1405 c, t dbSNP:5986312
1416 1416 a, g dbSNP:188695656
1419 1419 a, g dbSNP:764144814
1432 1432 a, c dbSNP:768590429
1440 1440 c, t dbSNP:774226070
1452 1452 c, g dbSNP:142297823
1459 1459 a, c dbSNP:780961204
1468 1468 a, g dbSNP:113973061
1472 1472 c, t dbSNP:138252531
1518 1518 a, g dbSNP:760647198
1544 1544 -, t dbSNP:200706633
1548 1548 c, g dbSNP:200185796
1550 1550 -, cttgt, ttgtc dbSNP:144517877
1550 1550 c, t dbSNP:201122952
1551 1551 -, ttgtc dbSNP:67830399
1553 1553 -, tcttt dbSNP:201713203
1554 1554 -, cttgt dbSNP:77680018
1575 1575 a, t dbSNP:376355382
1665 1665 c, g dbSNP:141881572
1671 1671 c, t dbSNP:193227969
1754 1754 c, g dbSNP:12845766
1760 1760 c, t dbSNP:184978385
1790 1790 c, g dbSNP:12845400
1869 1869 a, g dbSNP:28627635
1918 1918 c, t dbSNP:12845656

Target ORF information:

RefSeq Version NM_173523
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family B6 (MAGEB6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_173523

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGCCTCGGG GTCACAAGAG TAAGCTCCGT ACCTGTGAGA AACGCCAAGA GACCAATGGT 
CAGCCACAGG GTCTCACGGG TCCCCAGGCC ACTGCAGAGA AGCAGGAAGA GTCCCACTCT
TCCTCATCCT CTTCTCGCGC TTGTCTGGGT GATTGTCGTA GGTCTTCTGA TGCCTCCATT
CCTCAGGAGT CTCAGGGAGT GTCACCCACT GGGTCTCCTG ATGCAGTTGT TTCATATTCA
AAATCCGATG TGGCTGCCAA CGGCCAAGAT GAGAAAAGTC CAAGCACCTC CCGTGATGCC
TCCGTTCCTC AGGAGTCTCA GGGAGCTTCA CCCACTGGCT CTCCTGATGC AGGTGTTTCA
GGCTCAAAAT ATGATGTGGC TGCCAACGGC CAAGATGAGA AAAGTCCAAG CACTTCCCAT
GATGTCTCCG TTCCTCAGGA GTCTCAGGGA GCTTCACCCA CTGGCTCGCC TGATGCAGGT
GTTTCAGGCT CAAAATATGA TGTGGCTGCC GAGGGTGAAG ATGAGGAAAG TGTAAGCGCC
TCACAGAAAG CCATCATTTT TAAGCGCTTA AGCAAAGATG CTGTAAAGAA GAAGGCGTGC
ACGTTGGCGC AATTCCTGCA GAAGAAGTTT GAGAAGAAAG AGTCCATTTT GAAGGCAGAC
ATGCTGAAGT GTGTCCGCAG AGAGTACAAG CCCTACTTCC CTCAGATCCT CAACAGAACC
TCCCAACATT TGGTGGTGGC CTTTGGCGTT GAATTGAAAG AAATGGATTC CAGCGGCGAG
TCCTACACCC TTGTCAGCAA GCTAGGCCTC CCCAGTGAAG GAATTCTGAG TGGTGATAAT
GCGCTGCCGA AGTCGGGTCT CCTGATGTCG CTCCTGGTTG TGATCTTCAT GAACGGCAAC
TGTGCCACTG AAGAGGAGGT CTGGGAGTTC CTGGGTCTGT TGGGGATATA TGATGGGATC
CTGCATTCAA TCTATGGGGA TGCTCGGAAG ATCATTACTG AAGATTTGGT GCAAGATAAG
TACGTGGTTT ACCGGCAGGT GTGCAACAGT GATCCTCCAT GCTATGAGTT CCTGTGGGGT
CCACGAGCCT ATGCTGAAAC CACCAAGATG AGAGTCCTGC GTGTTTTGGC CGACAGCAGT
AACACCAGTC CCGGTTTATA CCCACATCTG TATGAAGACG CTTTGATAGA TGAGGTAGAG
AGAGCATTGA GACTGAGAGC TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.