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NKX2-3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol NKX2-3
Entrez Gene ID 159296
Full Name NK2 homeobox 3
Synonyms CSX3, NK2.3, NKX2.3, NKX2C, NKX4-3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10q24.2

Summary This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation.[provided by RefSeq, Mar 2010]. lac of sum
Disorder MIM:

606727


mRNA and Protein(s)

mRNA Protein Name
XM_011539369 XP_011537671 homeobox protein Nkx-2.3 isoform X1
XM_011539370 XP_011537672 homeobox protein Nkx-2.3 isoform X2
NM_145285 NP_660328 homeobox protein Nkx-2.3


Homo sapiens (human) NKX2-3 NP_660328.2
Pan troglodytes (chimpanzee) NKX2-3 XP_001166828.2
Macaca mulatta (Rhesus monkey) NKX2-3 XP_001106216.2
Canis lupus familiaris (dog) NKX2-3 XP_003640037.1
Bos taurus (cattle) NKX2-3 NP_001029848.1
Mus musculus (house mouse) Nkx2-3 NP_032725.1
Rattus norvegicus (Norway rat) Nkx2-3 NP_001101064.1
Danio rerio (zebrafish) nkx2.3 NP_571498.1
Xenopus (Silurana) tropicalis (western clawed frog) nkx2-3 XP_002937234.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following NKX2-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NKX2-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu77044 XM_011539369 PREDICTED: Homo sapiens NK2 homeobox 3 (NKX2-3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $139.30
$199.00
OHu77045 XM_011539370 PREDICTED: Homo sapiens NK2 homeobox 3 (NKX2-3), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu18132
NM_145285 Homo sapiens NK2 homeobox 3 (NKX2-3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu77044
Clone ID Related Accession (Same CDS sequence) XM_011539369
Accession Version XM_011539369.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 882bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product homeobox protein Nkx-2.3 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_030059.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGATGTTAC CAAGCCCGGT CACCTCCACC CCTTTCTCAG TCAAAGACAT TTTGAATCTG 
GAGCAGCAGC ACCAGCACTT CCATGGTGCG CACTTGCAGG CGGACTTGGA GCACCACTTC
CACTCTGCGC CCTGCATGCT GGCCGCCGCT GAGGGGACGC AATTTTCTGA CGGAGGGGAG
GAGGACGAGG AAGACGAGGG CGAGAAATTG TCCTATTTGA ACTCACTAGC CGCAGCAGAC
GGCCACGGGG ATTCAGGGCT GTGTCCCCAG GGCTATGTCC ACACGGTCCT GCGAGACTCG
TGCAGCGAGC CCAAGGAACA TGAAGAGGAG CCCGAGGTCG TGAGGGACCG GAGCCAAAAA
AGCTGCCAGC TGAAGAAGTC TCTAGAGACG GCCGGAGACT GCAAGGCGGC GGAGGAGAGC
GAGAGGCCGA AGCCACGCAG CCGCCGGAAG CCCCGGGTCC TCTTCTCGCA AGCCCAGGTC
TTCGAGCTGG AACGCAGGTT CAAGCAGCAG CGGTACCTGT CGGCACCCGA GCGCGAGCAC
CTCGCCAGCA GCCTGAAGCT CACATCCACT CAGGTGAAAA TCTGGTTCCA GAATCGCAGG
TACAAGTGCA AGAGACAGCG GCAGGACAAG TCTCTGGAGC TTGGCGCACA CGCGCCCCCG
CCGCCGCCGC GCCGCGTGGC TGTCCCGGTG CTGGTGCGGG ACGGCAAGCC GTGCGTCACG
CCCAGCGCGC AGGCCTACGG CGCGCCCTAC AGCGTGGGCG CCAGCGCCTA CTCCTACAAC
AGCTTCCCCG CCTACGGCTA TGGGAACTCG GCGGCGGGAC CTCCGCGGCG ACCACTGCCA
TGCAGCCCGC CTGCAGCGCG GCCGGAGGCG GCCCCTTTGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011537671.1
CDS191..1072
Misc Feature(1)635..811(+)
Misc Feature(2)635..805(+)
Misc Feature(3)641..793(+)
Translation

Target ORF information:

RefSeq Version XM_011539369
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens NK2 homeobox 3 (NKX2-3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011539369

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGATGTTAC CAAGCCCGGT CACCTCCACC CCTTTCTCAG TCAAAGACAT TTTGAATCTG 
GAGCAGCAGC ACCAGCACTT CCATGGTGCG CACTTGCAGG CGGACTTGGA GCACCACTTC
CACTCTGCGC CCTGCATGCT GGCCGCCGCT GAGGGGACGC AATTTTCTGA CGGAGGGGAG
GAGGACGAGG AAGACGAGGG CGAGAAATTG TCCTATTTGA ACTCACTAGC CGCAGCAGAC
GGCCACGGGG ATTCAGGGCT GTGTCCCCAG GGCTATGTCC ACACGGTCCT GCGAGACTCG
TGCAGCGAGC CCAAGGAACA TGAAGAGGAG CCCGAGGTCG TGAGGGACCG GAGCCAAAAA
AGCTGCCAGC TGAAGAAGTC TCTAGAGACG GCCGGAGACT GCAAGGCGGC GGAGGAGAGC
GAGAGGCCGA AGCCACGCAG CCGCCGGAAG CCCCGGGTCC TCTTCTCGCA AGCCCAGGTC
TTCGAGCTGG AACGCAGGTT CAAGCAGCAG CGGTACCTGT CGGCACCCGA GCGCGAGCAC
CTCGCCAGCA GCCTGAAGCT CACATCCACT CAGGTGAAAA TCTGGTTCCA GAATCGCAGG
TACAAGTGCA AGAGACAGCG GCAGGACAAG TCTCTGGAGC TTGGCGCACA CGCGCCCCCG
CCGCCGCCGC GCCGCGTGGC TGTCCCGGTG CTGGTGCGGG ACGGCAAGCC GTGCGTCACG
CCCAGCGCGC AGGCCTACGG CGCGCCCTAC AGCGTGGGCG CCAGCGCCTA CTCCTACAAC
AGCTTCCCCG CCTACGGCTA TGGGAACTCG GCGGCGGGAC CTCCGCGGCG ACCACTGCCA
TGCAGCCCGC CTGCAGCGCG GCCGGAGGCG GCCCCTTTGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu77045
Clone ID Related Accession (Same CDS sequence) XM_011539370
Accession Version XM_011539370.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 585bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product homeobox protein Nkx-2.3 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_030059.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGATGTTAC CAAGCCCGGT CACCTCCACC CCTTTCTCAG TCAAAGACAT TTTGAATCTG 
GAGCAGCAGC ACCAGCACTT CCATGGTGCG CACTTGCAGG CGGACTTGGA GCACCACTTC
CACTCTGCGC CCTGCATGCT GGCCGCCGCT GAGGGGACGC AATTTTCTGA CGGAGGGGAG
GAGGACGAGG AAGACGAGGG CGAGAAATTG TCCTATTTGA ACTCACTAGC CGCAGCAGAC
GGCCACGGGG ATTCAGGGCT GTGTCCCCAG GGCTATGTCC ACACGGTCCT GCGAGACTCG
TGCAGCGAGC CCAAGGAACA TGAAGAGGAG CCCGAGGTCG TGAGGGACCG GAGCCAAAAT
GCTCAAGATC CAAATAAACA CGCACTAACT ACCCCTCTCC ACGAAACGCG CCTCCGCCTG
CTAAGGGCGT TCTTTGGGTA CTGGGGCTGT CTCAGGGTCC CACAGCGCCA GGAGCCACAA
ACGTTCCCAA AAGTCCAGCC ATTTACTACC GCACGCTCTG CGCAGCCACC AAAAAGGGTC
ACGGTGCTCC AGGACAGGAG CCGCGGTGCG GCCGGGAACA GCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011537672.1
CDS191..775
Translation

Target ORF information:

RefSeq Version XM_011539370
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens NK2 homeobox 3 (NKX2-3), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011539370

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGATGTTAC CAAGCCCGGT CACCTCCACC CCTTTCTCAG TCAAAGACAT TTTGAATCTG 
GAGCAGCAGC ACCAGCACTT CCATGGTGCG CACTTGCAGG CGGACTTGGA GCACCACTTC
CACTCTGCGC CCTGCATGCT GGCCGCCGCT GAGGGGACGC AATTTTCTGA CGGAGGGGAG
GAGGACGAGG AAGACGAGGG CGAGAAATTG TCCTATTTGA ACTCACTAGC CGCAGCAGAC
GGCCACGGGG ATTCAGGGCT GTGTCCCCAG GGCTATGTCC ACACGGTCCT GCGAGACTCG
TGCAGCGAGC CCAAGGAACA TGAAGAGGAG CCCGAGGTCG TGAGGGACCG GAGCCAAAAT
GCTCAAGATC CAAATAAACA CGCACTAACT ACCCCTCTCC ACGAAACGCG CCTCCGCCTG
CTAAGGGCGT TCTTTGGGTA CTGGGGCTGT CTCAGGGTCC CACAGCGCCA GGAGCCACAA
ACGTTCCCAA AAGTCCAGCC ATTTACTACC GCACGCTCTG CGCAGCCACC AAAAAGGGTC
ACGGTGCTCC AGGACAGGAG CCGCGGTGCG GCCGGGAACA GCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18132
Clone ID Related Accession (Same CDS sequence) NM_145285
Accession Version NM_145285.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1095bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product homeobox protein Nkx-2.3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI764885.1, BC025788.1 and AL353719.10. This sequence is a reference standard in the RefSeqGene project. On Jun 9, 2007 this sequence version replaced gi:21699077. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by orthologous data and transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI764885.1, AK300856.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGATGTTAC CAAGCCCGGT CACCTCCACC CCTTTCTCAG TCAAAGACAT TTTGAATCTG 
GAGCAGCAGC ACCAGCACTT CCATGGTGCG CACTTGCAGG CGGACTTGGA GCACCACTTC
CACTCTGCGC CCTGCATGCT GGCCGCCGCT GAGGGGACGC AATTTTCTGA CGGAGGGGAG
GAGGACGAGG AAGACGAGGG CGAGAAATTG TCCTATTTGA ACTCACTAGC CGCAGCAGAC
GGCCACGGGG ATTCAGGGCT GTGTCCCCAG GGCTATGTCC ACACGGTCCT GCGAGACTCG
TGCAGCGAGC CCAAGGAACA TGAAGAGGAG CCCGAGGTCG TGAGGGACCG GAGCCAAAAA
AGCTGCCAGC TGAAGAAGTC TCTAGAGACG GCCGGAGACT GCAAGGCGGC GGAGGAGAGC
GAGAGGCCGA AGCCACGCAG CCGCCGGAAG CCCCGGGTCC TCTTCTCGCA AGCCCAGGTC
TTCGAGCTGG AACGCAGGTT CAAGCAGCAG CGGTACCTGT CGGCACCCGA GCGCGAGCAC
CTCGCCAGCA GCCTGAAGCT CACATCCACT CAGGTGAAAA TCTGGTTCCA GAATCGCAGG
TACAAGTGCA AGAGACAGCG GCAGGACAAG TCTCTGGAGC TTGGCGCACA CGCGCCCCCG
CCGCCGCCGC GCCGCGTGGC TGTCCCGGTG CTGGTGCGGG ACGGCAAGCC GTGCGTCACG
CCCAGCGCGC AGGCCTACGG CGCGCCCTAC AGCGTGGGCG CCAGCGCCTA CTCCTACAAC
AGCTTCCCCG CCTACGGCTA TGGGAACTCG GCCGCGGCCG CCGCCGCCGC CGCCGCCGCC
GCCGCAGCAG CGGCGGCCTA CAGCAGCAGC TATGGCTGTG CGTACCCGGC GGGCGGCGGC
GGCGGCGGCG GCGGGACCTC CGCGGCGACC ACTGCCATGC AGCCCGCCTG CAGCGCGGCC
GGAGGCGGCC CCTTTGTGAA CGTGAGCAAC CTAGGAGGCT TCGGCAGCGG CGGCAGCGCA
CAGCCGTTGC ACCAGGGTAC TGCAGCCGGG GCCGCGTGCG CTCAGGGCAC CTTGCAGGGC
ATCCGGGCCT GGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_660328.2
CDS200..1294
Misc Feature(1)188..190(+)
Misc Feature(2)644..820(+)
Misc Feature(3)644..814(+)
Misc Feature(4)650..802(+)
Exon (1)1..557
Gene:NKX2-3
Gene Synonym:
Exon (2)558..2097
Gene:NKX2-3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_145285
Organism Homo sapiens (human)
Definition Homo sapiens NK2 homeobox 3 (NKX2-3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_145285

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGATGTTAC CAAGCCCGGT CACCTCCACC CCTTTCTCAG TCAAAGACAT TTTGAATCTG 
GAGCAGCAGC ACCAGCACTT CCATGGTGCG CACTTGCAGG CGGACTTGGA GCACCACTTC
CACTCTGCGC CCTGCATGCT GGCCGCCGCT GAGGGGACGC AATTTTCTGA CGGAGGGGAG
GAGGACGAGG AAGACGAGGG CGAGAAATTG TCCTATTTGA ACTCACTAGC CGCAGCAGAC
GGCCACGGGG ATTCAGGGCT GTGTCCCCAG GGCTATGTCC ACACGGTCCT GCGAGACTCG
TGCAGCGAGC CCAAGGAACA TGAAGAGGAG CCCGAGGTCG TGAGGGACCG GAGCCAAAAA
AGCTGCCAGC TGAAGAAGTC TCTAGAGACG GCCGGAGACT GCAAGGCGGC GGAGGAGAGC
GAGAGGCCGA AGCCACGCAG CCGCCGGAAG CCCCGGGTCC TCTTCTCGCA AGCCCAGGTC
TTCGAGCTGG AACGCAGGTT CAAGCAGCAG CGGTACCTGT CGGCACCCGA GCGCGAGCAC
CTCGCCAGCA GCCTGAAGCT CACATCCACT CAGGTGAAAA TCTGGTTCCA GAATCGCAGG
TACAAGTGCA AGAGACAGCG GCAGGACAAG TCTCTGGAGC TTGGCGCACA CGCGCCCCCG
CCGCCGCCGC GCCGCGTGGC TGTCCCGGTG CTGGTGCGGG ACGGCAAGCC GTGCGTCACG
CCCAGCGCGC AGGCCTACGG CGCGCCCTAC AGCGTGGGCG CCAGCGCCTA CTCCTACAAC
AGCTTCCCCG CCTACGGCTA TGGGAACTCG GCCGCGGCCG CCGCCGCCGC CGCCGCCGCC
GCCGCAGCAG CGGCGGCCTA CAGCAGCAGC TATGGCTGTG CGTACCCGGC GGGCGGCGGC
GGCGGCGGCG GCGGGACCTC CGCGGCGACC ACTGCCATGC AGCCCGCCTG CAGCGCGGCC
GGAGGCGGCC CCTTTGTGAA CGTGAGCAAC CTAGGAGGCT TCGGCAGCGG CGGCAGCGCA
CAGCCGTTGC ACCAGGGTAC TGCAGCCGGG GCCGCGTGCG CTCAGGGCAC CTTGCAGGGC
ATCCGGGCCT GGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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