Email to GenScript

DPYD dihydropyrimidine dehydrogenase [Homo sapiens (human)]

Gene Symbol DPYD
Entrez Gene ID 1806
Full Name dihydropyrimidine dehydrogenase
Synonyms DHP, DHPDHASE, DPD
General protein information
Preferred Names
dihydropyrimidine dehydrogenase [NADP(+)]
Names
dihydropyrimidine dehydrogenase [NADP(+)]
dihydrouracil dehydrogenase
dihydrothymine dehydrogenase
NP_000101.2
NP_001153773.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p22

Summary The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]. lac of sum
Disorder MIM:

612779

Disorder Html: Dihydropyrimidine dehydrogenase deficiency, 274270 (3);





The following DPYD gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DPYD gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu33082 XM_005270562 PREDICTED: Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu33083 XM_006710397 PREDICTED: Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu19551 NM_000110 Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu21185 NM_001160301 Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$69.3
$99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu33082
Accession Version XM_005270562.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2862bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product dihydropyrimidine dehydrogenase [NADP(+)] isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578798493. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGGCCCCTG TGCTCAGTAA GGACTCGGCG GACATCGAGA GTATCCTGGC TTTAAATCCT 
CGAACACAAA CTCATGCAAC TCTGTGTTCC ACTTCGGCCA AGAAATTAGA CAAGAAACAT
TGGAAAAGAA ATCCTGATAA GAACTGCTTT AATTGTGAGA AGCTGGAGAA TAATTTTGAT
GACATCAAGC ACACGACTCT TGGTGAGCGA GGAGCTCTCC GAGAAGCAAT GAGATGCCTG
AAATGTGCAG ATGCCCCGTG TCAGAAGAGC TGTCCAACTA ATCTTGATAT TAAATCATTC
ATCACAAGTA TTGCAAACAA GAACTATTAT GGAGCTGCTA AGATGATATT TTCTGACAAC
CCACTTGGTC TGACTTGTGG AATGGTATGT CCAACCTCTG ATCTTTGTGT AGGTGGATGC
AATTTATATG CCACTGAAGA GGGACCCATT AATATTGGTG GATTGCAGCA ATTTGCTACT
GAGGTATTCA AAGCAATGAG TATCCCACAG ATCAGAAATC CTTCGCTGCC TCCCCCAGAA
AAAATGTCTG AAGCCTATTC TGCAAAGATT GCTCTTTTTG GTGCTGGGCC TGCAAGTATA
AGTTGTGCTT CCTTTTTGGC TCGATTGGGG TACTCTGACA TCACTATATT TGAAAAACAA
GAATATGTTG GTGGTTTAAG TACTTCTGAA ATTCCTCAGT TCCGGCTGCC GTATGATGTA
GTGAATTTTG AGATTGAGCT AATGAAGGAC CTTGGTGTAA AGATAATTTG CGGTAAAAGC
CTTTCAGTGA ATGAAATGAC TCTTAGCACT TTGAAAGAAA AAGGCTACAA AGCTGCTTTC
ATTGGAATAG GTTTGCCAGA ACCCAATAAA GATGCCATCT TCCAAGGCCT GACGCAGGAC
CAGGGGTTTT ATACATCCAA AGACTTTTTG CCACTTGTAG CCAAAGGCAG TAAAGCAGGA
ATGTGCGCCT GTCACTCTCC ATTGCCATCG ATACGGGGAG TCGTGATTGT ACTTGGAGCT
GGAGACACTG CCTTTGACTG TGCAACATCT GCTCTACGTT GTGGAGCTCG CCGTGTGTTC
ATCGTCTTCA GAAAAGGCTT TGTTAATATA AGAGCTGTCC CTGAGGAGAT GGAACTTGCT
AAGGAAGAAA AGTGTGAATT TCTGCCATTC CTGTCCCCAC GGAAGGTTAT AGTAAAAGGT
GGGAGAATTG TTGCTATGCA GTTTGTTCGG ACAGAGCAAG ATGAAACTGG AAAATGGAAT
GAAGATGAAG ATCAGATGGT CCATCTGAAA GCCGATGTGG TCATCAGTGC CTTTGGTTCA
GTTCTGAGTG ATCCTAAAGT AAAAGAAGCC TTGAGCCCTA TAAAATTTAA CAGATGGGGT
CTCCCAGAAG TAGATCCAGA AACTATGCAA ACTAGTGAAG CATGGGTATT TGCAGGTGGT
GATGTCGTTG GTTTGGCTAA CACTACAGTG GAATCGGTGA ATGATGGAAA GCAAGCTTCT
TGGTACATTC ACAAATACGT ACAGGACATT GTGACAAATG TTTCCCCCAG AATCATCCGG
GGAACCACCT CTGGCCCCAT GTATGGCCCT GGACAAAGCT CCTTTCTGAA TATTGAGCTC
ATCAGTGAGA AAACGGCTGC ATATTGGTGT CAAAGTGTCA CTGAACTAAA GGCTGACTTT
CCAGACAACA TTGTGATTGC TAGCATTATG TGCAGTTACA ATAAAAATGA CTGGACGGAA
CTTGCCAAGA AGTCTGAGGA TTCTGGAGCA GATGCCCTGG AGTTAAATTT ATCATGTCCA
CATGGCATGG GAGAAAGAGG AATGGGCCTG GCCTGTGGGC AGGATCCAGA GCTGGTGCGG
AACATCTGCC GCTGGGTTAG GCAAGCTGTT CAGATTCCTT TTTTTGCCAA GCTGACCCCA
AATGTCACTG ATATTGTGAG CATCGCAAGA GCTGCAAAGG AAGGTGGTGC CAATGGCGTT
ACAGCCACCA ACACTGTCTC AGGTCTGATG GGATTAAAAT CTGATGGCAC ACCTTGGCCA
GCAGTGGGGA TTGCAAAGCG AACTACATAT GGAGGAGTGT CTGGGACAGC AATCAGACCT
ATTGCTTTGA GAGCTGTGAC CTCCATTGCT CGTGCTCTGC CTGGATTTCC CATTTTGGCT
ACTGGTGGAA TTGACTCTGC TGAAAGTGGT CTTCAGTTTC TCCATAGTGG TGCTTCCGTC
CTCCAGGTAT GCAGTGCCAT TCAGAATCAG GATTTCACTG TGATCGAAGA CTACTGCACT
GGCCTCAAAG CCCTGCTTTA TCTGAAAAGC ATTGAAGAAC TACAAGACTG GGATGGACAG
AGTCCAGCTA CTGTGAGTCA CCAGAAAGGG AAACCAGTTC CACGTATAGC TGAACTCATG
GACAAGAAAC TGCCAAGTTT TGGACCTTAT CTGGAACAGC GCAAGAAAAT CATAGCAGAA
AACAAGATTA GACTGAAAGA ACAAAATGTA GCTTTTTCAC CACTTAAGAG AAACTGTTTT
ATCCCCAAAA GGCCTATTCC TACCATCAAG GATGTAATAG GAAAAGCACT GCAGTACCTT
GGAACATTTG GTGAATTGAG CAACGTAGAG CAAGTTGTGG CTATGATTGA TGAAGAAATG
TGTATCAACT GTGGTAAATG CTACATGACC TGTAATGATT CTGGCTACCA GGCTATACAG
TTTGATCCAG AAACCCACCT GCCCACCATA ACCGACACTT GTACAGGCTG TACTCTGTGT
CTCAGTGTTT GCCCTATTGT CGACTGCATC AAAATGGTTT CCAGGACAAC ACCTTATGAA
CCAAAGAGAG GCGTACCCTT ATCTGTGAAT CCGGTGTGTT AA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005270619.2
CDS138..2999
Misc Feature(1)294..1661(+)
Misc Feature(2)309..635(+)
Misc Feature(3)717..>851(+)
Misc Feature(4)1662..2423(+)
Misc Feature(5)1668..2396(+)
Misc Feature(6)1689..2132(+)
Misc Feature(7)1689..2132(+)
Misc Feature(8)1746..2132(+)
Misc Feature(9)2757..2933(+)
Misc Feature(10)2772..2912(+)
Translation
Position Chain Variation Link
1 1 c, g dbSNP:529162686
28 28 c, t dbSNP:534300645
39 39 a, t dbSNP:571741157
46 46 a, g dbSNP:551486678
50 50 a, t dbSNP:531689464
52 52 c, t dbSNP:569146754
63 63 a, g dbSNP:550078641
89 89 a, g dbSNP:758152525
92 92 g, t dbSNP:752581618
94 94 a, c dbSNP:765165101
95 95 a, g dbSNP:754506010
96 96 c, g dbSNP:529923798
120 120 c, g dbSNP:577136443
125 125 g, t dbSNP:760379014
138 138 a, c dbSNP:772950053
140 140 a, g dbSNP:768020954
144 144 c, t dbSNP:762198241
150 150 c, t dbSNP:772097379
158 158 a, g dbSNP:774730464
160 160 a, t dbSNP:769190350
167 167 g, t dbSNP:749369964
173 173 c, g dbSNP:376273539
174 174 a, g dbSNP:769820114
182 182 a, c, t dbSNP:267598790
183 183 c, g dbSNP:150036960
184 184 c, t dbSNP:764555085
185 185 a, g dbSNP:763165014
196 196 c, g dbSNP:753217888
198 198 c, t dbSNP:72549310
199 199 a, g dbSNP:80081766
210 210 c, t dbSNP:775601164
211 211 a, c dbSNP:776662759
213 213 a, g dbSNP:766635900
216 216 a, t dbSNP:770229152
222 222 c, t dbSNP:1801265
223 223 a, g dbSNP:528768620
228 228 a, g dbSNP:768501828
232 232 c, t dbSNP:748974194
233 233 a, g dbSNP:775622568
237 237 a, g dbSNP:769847078
254 254 a, g dbSNP:745409341
264 264 a, g dbSNP:780873985
274 274 a, g dbSNP:756684474
278 278 a, g dbSNP:746681994
279 279 a, g dbSNP:777238016
287 287 c, t dbSNP:370036611
295 295 a, g dbSNP:757958938
302 302 a, g dbSNP:139126323
314 314 c, t dbSNP:779270411
323 323 c, t dbSNP:181215161
324 324 a, g dbSNP:367619008
331 331 c, g, t dbSNP:371587702
345 345 c, t dbSNP:141597515
346 346 a, g dbSNP:767818267
355 355 g, t dbSNP:762102298
357 357 c, t dbSNP:189768576
364 364 c, t dbSNP:765131182
366 366 a, g dbSNP:527580106
369 369 a, t dbSNP:776692894
390 390 a, g dbSNP:757342874
394 394 c, t dbSNP:568132506
395 395 a, g, t dbSNP:201841475
397 397 g, t dbSNP:528152707
402 402 a, t dbSNP:672601289
406 406 g, t dbSNP:672601288
411 411 c, g dbSNP:143986398
413 413 a, c dbSNP:766389732
415 415 c, g dbSNP:760553268
423 423 c, g dbSNP:773159364
424 424 a, t dbSNP:771573678
425 425 c, t dbSNP:761254577
427 427 c, t dbSNP:375990187
432 432 -, tcat dbSNP:72549309
436 436 -, tcat dbSNP:539032572
437 437 c, t dbSNP:774047246
447 447 a, g dbSNP:768288280
449 449 g, t dbSNP:749699298
450 450 a, g dbSNP:150385342
452 452 a, g dbSNP:770144122
461 461 a, c dbSNP:762430779
469 469 a, g dbSNP:762533012
479 479 g, t dbSNP:370615432
480 480 a, g dbSNP:141462178
482 482 c, g dbSNP:377169736
494 494 c, t dbSNP:777348913
496 496 a, g dbSNP:771534236
500 500 a, c dbSNP:747135235
504 504 a, g dbSNP:778022685
516 516 a, g dbSNP:758514990
523 523 g, t dbSNP:748320430
530 530 a, g dbSNP:779135187
531 531 a, t dbSNP:538336580
532 532 c, t dbSNP:750224169
547 547 c, t dbSNP:767482279
551 551 g, t dbSNP:757163217
554 554 a, g dbSNP:751448860
561 561 g, t dbSNP:763623595
568 568 c, g dbSNP:762468894
569 569 c, t dbSNP:775065182
578 578 a, g dbSNP:764939839
581 581 a, g dbSNP:56108357
584 584 c, g dbSNP:759858246
588 588 a, g dbSNP:200562975
600 600 c, t dbSNP:201443458
604 604 a, g dbSNP:536577604
611 611 c, t dbSNP:190771411
626 626 a, c dbSNP:368970772
633 633 a, g dbSNP:2297595
634 634 c, t dbSNP:763061658
635 635 a, g dbSNP:139834141
637 637 g, t dbSNP:775526810
644 644 a, g dbSNP:765252243
658 658 c, g dbSNP:374827081
661 661 c, g, t dbSNP:371792178
662 662 a, g dbSNP:6670886
668 668 g, t dbSNP:774411340
670 670 a, c dbSNP:768680499
679 679 a, c dbSNP:672601287
681 681 -, a dbSNP:754785410
681 681 a, g dbSNP:748853941
682 682 a, t dbSNP:779728902
690 690 a, g dbSNP:374531732
693 693 g, t dbSNP:755645831
694 694 a, g dbSNP:115232898
705 705 a, g dbSNP:368152149
707 707 c, t dbSNP:149843476
718 718 a, g, t dbSNP:751841116
726 726 a, c dbSNP:764635955
728 728 c, t dbSNP:758927521
729 729 c, g dbSNP:753166888
730 730 a, c dbSNP:765309287
732 732 a, g dbSNP:759479759
733 733 a, g dbSNP:776973423
734 734 c, t dbSNP:766503499
738 738 a, c dbSNP:72549308
743 743 c, t dbSNP:773991224
749 749 c, g dbSNP:768519000
756 756 a, g dbSNP:749269410
758 758 a, g, t dbSNP:769440759
760 760 a, g, t dbSNP:376073289
769 769 a, g dbSNP:72549307
776 776 c, t dbSNP:190048823
783 783 a, g dbSNP:778141885
790 790 a, g dbSNP:758699471
793 793 a, g dbSNP:781184141
798 798 g, t dbSNP:146170505
807 807 g, t dbSNP:755155824
809 809 c, t dbSNP:753828034
840 840 c, t dbSNP:1801266
841 841 a, g dbSNP:755416212
842 842 a, g dbSNP:754317478
846 846 c, t dbSNP:267598789
847 847 c, t dbSNP:780025995
848 848 a, g dbSNP:139863300
852 852 a, g dbSNP:750687600
870 870 a, g dbSNP:767836989
876 876 a, c, t dbSNP:376128878
891 891 g, t dbSNP:765034707
893 893 c, t dbSNP:6675198
905 905 g, t dbSNP:556933127
907 907 a, g dbSNP:764945792
908 908 c, t dbSNP:754745863
909 909 a, g dbSNP:141726921
912 912 a, g dbSNP:45589337
915 915 a, g dbSNP:760222167
917 917 c, t dbSNP:772684506
932 932 a, g dbSNP:766962931
939 939 c, g dbSNP:761479700
940 940 a, t dbSNP:773983635
943 943 a, g dbSNP:768915005
944 944 c, t dbSNP:200702346
946 946 c, g dbSNP:775926386
953 953 a, g dbSNP:770391936
959 959 -, a dbSNP:749881640
977 977 c, t dbSNP:557212505
978 978 a, t dbSNP:746329786
979 979 c, t dbSNP:369103276
980 980 c, t dbSNP:781454573
988 988 a, g, t dbSNP:777220476
991 991 c, t dbSNP:771194906
993 993 c, t dbSNP:751113340
1005 1005 a, g dbSNP:146356975
1006 1006 a, g dbSNP:672601285
1007 1007 a, t dbSNP:777902288
1009 1009 a, g dbSNP:772320654
1012 1012 c, t dbSNP:748266854
1013 1013 c, t dbSNP:187484874
1014 1014 a, c dbSNP:779925747
1020 1020 -, c dbSNP:772507658
1024 1024 a, g dbSNP:672601284
1030 1030 a, c, t dbSNP:143879757
1031 1031 a, g dbSNP:61758443
1040 1040 a, g, t dbSNP:751049055
1047 1047 c, t dbSNP:183105782
1059 1059 -, g dbSNP:759965732
1064 1064 c, t dbSNP:762699533
1066 1066 c, t dbSNP:150437414
1071 1071 c, t dbSNP:145112791
1075 1075 c, t dbSNP:759967863
1084 1084 g, t dbSNP:749157068
1087 1087 a, g dbSNP:777347164
1092 1092 a, g dbSNP:771536388
1103 1103 c, t dbSNP:768834079
1104 1104 a, g dbSNP:201018345
1112 1112 c, t dbSNP:141376128
1113 1113 c, t dbSNP:770566506
1114 1114 c, t dbSNP:575763449
1116 1116 c, t dbSNP:369575517
1126 1126 c, t dbSNP:777560627
1131 1131 c, t dbSNP:757994597
1132 1132 a, g dbSNP:747633945
1135 1135 c, g dbSNP:778760295
1139 1139 a, c, t dbSNP:753504491
1140 1140 a, g, t dbSNP:72549306
1144 1144 c, t dbSNP:756372042
1145 1145 a, t dbSNP:750994754
1148 1148 a, t dbSNP:767903251
1151 1151 g, t dbSNP:761991197
1157 1157 g, t dbSNP:774390439
1158 1158 a, g dbSNP:764111543
1161 1161 a, g dbSNP:183385770
1162 1162 a, g dbSNP:769709846
1166 1166 c, t dbSNP:770818300
1172 1172 c, t dbSNP:1042478
1177 1177 a, g dbSNP:746777181
1181 1181 a, g dbSNP:773243157
1185 1185 c, t dbSNP:771885007
1191 1191 -, c dbSNP:771024192
1191 1191 c, g dbSNP:190577302
1194 1194 c, t dbSNP:143154602
1195 1195 a, g dbSNP:778601245
1204 1204 c, t dbSNP:754467630
1206 1206 c, t dbSNP:748958293
1207 1207 a, g dbSNP:377143350
1209 1209 c, t dbSNP:779557503
1210 1210 a, g dbSNP:573299212
1211 1211 a, t dbSNP:1042479
1213 1213 a, t dbSNP:750721736
1217 1217 c, g dbSNP:745704371
1218 1218 a, g dbSNP:768117152
1220 1220 c, t dbSNP:372369973
1221 1221 a, g dbSNP:752020412
1226 1226 c, t dbSNP:764173823
1229 1229 a, c dbSNP:763008163
1234 1234 g, t dbSNP:752985272
1245 1245 a, g dbSNP:72549305
1246 1246 -, ta dbSNP:749571474
1246 1246 c, t dbSNP:760570391
1254 1254 a, g dbSNP:772906420
1257 1257 c, t dbSNP:201785202
1262 1262 a, g dbSNP:761850800
1266 1266 a, g dbSNP:144935781
1269 1269 c, g dbSNP:201648613
1271 1271 a, g dbSNP:1126741
1277 1277 c, t dbSNP:150759598
1292 1292 -, tg dbSNP:769925158
1293 1293 -, catcac dbSNP:777662767
1293 1293 g, t dbSNP:78060119
1294 1294 -, c dbSNP:748023289
1294 1294 a, t dbSNP:576409484
1304 1304 a, g dbSNP:753482702
1306 1306 c, t dbSNP:754028972
1307 1307 a, c dbSNP:767437717
1317 1317 a, c, t dbSNP:140602333
1318 1318 g, t dbSNP:143815742
1326 1326 a, g dbSNP:762598766
1341 1341 -, a dbSNP:781098341
1346 1346 c, t dbSNP:267598788
1348 1348 g, t dbSNP:774883578
1350 1350 a, g dbSNP:769306962
1351 1351 c, t dbSNP:745512069
1353 1353 a, g dbSNP:780885126
1355 1355 a, g dbSNP:61622928
1365 1365 a, c, t dbSNP:528430685
1366 1366 a, g dbSNP:199646142
1373 1373 a, g dbSNP:56038477
1378 1378 a, g dbSNP:778867644
1380 1380 g, t dbSNP:755031341
1391 1391 a, g dbSNP:141370079
1397 1397 a, t dbSNP:200064537
1401 1401 c, g dbSNP:766700777
1402 1402 a, g dbSNP:757155354
1408 1408 a, t dbSNP:751374989
1409 1409 a, c, t dbSNP:532341730
1414 1414 c, t dbSNP:751340819
1415 1415 a, g, t dbSNP:764666241
1416 1416 g, t dbSNP:759082282
1417 1417 c, t dbSNP:200693895
1430 1430 c, t dbSNP:770549765
1431 1431 a, g dbSNP:142512579
1433 1433 c, t dbSNP:773600085
1434 1434 c, g dbSNP:772358811
1437 1437 c, g dbSNP:748620513
1438 1438 c, t dbSNP:779465366
1438 1438 -, t dbSNP:754978663
1444 1444 a, c, g dbSNP:370569731
1445 1445 a, t dbSNP:749354734
1448 1448 c, t dbSNP:780469489
1451 1451 g, t dbSNP:186169810
1463 1463 a, g dbSNP:750632457
1471 1471 c, g dbSNP:763984510
1472 1472 g, t dbSNP:758154006
1474 1474 a, c dbSNP:200709381
1481 1481 a, g dbSNP:752516372
1486 1486 c, g, t dbSNP:72975710
1494 1494 c, t dbSNP:753710779
1495 1495 a, c, g dbSNP:144395748
1506 1506 a, g dbSNP:750147471
1508 1508 c, t dbSNP:57918000
1516 1516 -, g dbSNP:779948148
1528 1528 c, t dbSNP:370707404
1529 1529 a, g dbSNP:373724295
1533 1533 c, t dbSNP:774799003
1540 1540 a, c dbSNP:199549923
1543 1543 c, t dbSNP:763557204
1552 1552 a, g dbSNP:776082092
1553 1553 c, t dbSNP:770056548
1575 1575 a, g dbSNP:745911874
1583 1583 c, t dbSNP:376470184
1584 1584 a, g dbSNP:141439344
1592 1592 a, g dbSNP:560012397
1593 1593 a, g dbSNP:747161261
1602 1602 a, g dbSNP:778776264
1612 1612 c, t dbSNP:72549304
1613 1613 a, g dbSNP:753835178
1618 1618 a, g dbSNP:779967271
1621 1621 a, g dbSNP:111858276
1631 1631 a, g, t dbSNP:116364703
1635 1635 g, t dbSNP:766885021
1642 1642 a, g dbSNP:761555670
1644 1644 a, g dbSNP:751104498
1655 1655 c, t dbSNP:201166313
1656 1656 a, g dbSNP:138391898
1658 1658 a, t dbSNP:373838132
1661 1661 a, g dbSNP:775930761
1664 1664 c, t dbSNP:555178721
1678 1678 c, t dbSNP:374527058
1691 1691 -, tc dbSNP:768130933
1695 1695 c, t dbSNP:59086055
1696 1696 a, g dbSNP:138616379
1698 1698 a, g dbSNP:145773863
1699 1699 a, g dbSNP:758489611
1702 1702 a, c dbSNP:759249769
1704 1704 a, g dbSNP:765465250
1708 1708 c, g dbSNP:756020314
1717 1717 c, t dbSNP:147601618
1718 1718 c, g dbSNP:767376585
1729 1729 a, g dbSNP:371258350
1739 1739 c, g dbSNP:774290851
1747 1747 a, c dbSNP:763572567
1753 1753 a, t dbSNP:762523739
1757 1757 a, c dbSNP:151216654
1758 1758 a, c, g dbSNP:769466648
1767 1767 a, c dbSNP:368146607
1770 1770 a, g dbSNP:776984091
1771 1771 c, t dbSNP:753707032
1772 1772 a, g dbSNP:747571447
1778 1778 a, g dbSNP:778338661
1780 1780 a, g, t dbSNP:748235192
1786 1786 a, g dbSNP:201433243
1817 1817 c, t dbSNP:17376848
1819 1819 -, c dbSNP:72549303
1822 1822 a, g dbSNP:200296941
1826 1826 c, g, t dbSNP:3918289
1827 1827 a, c dbSNP:55971861
1841 1841 c, t dbSNP:758391723
1849 1849 g, t dbSNP:752518145
1852 1852 a, g dbSNP:548783838
1858 1858 a, g dbSNP:780120302
1871 1871 c, g dbSNP:753527420
1873 1873 c, t dbSNP:765990958
1874 1874 a, g dbSNP:267598787
1884 1884 a, g dbSNP:529019871
1885 1885 a, g dbSNP:773652644
1911 1911 g, t dbSNP:138545885
1912 1912 c, t dbSNP:749982106
1923 1923 a, c dbSNP:767986711
1928 1928 a, t dbSNP:762083671
1936 1936 c, g dbSNP:763784786
1942 1942 a, g dbSNP:137999090
1944 1944 a, g dbSNP:763506271
1948 1948 a, g dbSNP:575853463
1953 1953 a, g dbSNP:769696395
1957 1957 a, g dbSNP:746115989
1960 1960 c, t dbSNP:187713395
1964 1964 -, cctggcctgtgggcag dbSNP:773499329
1970 1970 c, g dbSNP:183475941
1972 1972 g, t dbSNP:747872037
1981 1981 a, c dbSNP:755692084
1992 1992 g, t dbSNP:202212118
1995 1995 c, t dbSNP:538703919
1996 1996 a, g dbSNP:375436137
2001 2001 a, g dbSNP:756890859
2007 2007 c, t dbSNP:751190912
2008 2008 a, g dbSNP:778298325
2012 2012 a, c, g dbSNP:753296078
2018 2018 g, t dbSNP:765640386
2022 2022 a, g dbSNP:760038956
2033 2033 -, t dbSNP:770063428
2036 2036 a, t dbSNP:753891721
2038 2038 g, t dbSNP:766411970
2054 2054 a, c dbSNP:768101874
2058 2058 a, g dbSNP:773407491
2060 2060 a, t dbSNP:768507975
2062 2062 c, t dbSNP:569661196
2066 2066 c, t dbSNP:775551741
2078 2078 c, t dbSNP:769645315
2081 2081 a, c, t dbSNP:780572158
2082 2082 a, g dbSNP:145548112
2107 2107 c, t dbSNP:146529561
2114 2114 c, t dbSNP:139543981
2115 2115 a, g dbSNP:1801160
2116 2116 g, t dbSNP:60511679
2131 2131 c, t dbSNP:570122671
2133 2133 c, g dbSNP:368327291
2142 2142 c, g dbSNP:767547827
2150 2150 a, g dbSNP:757475393
2177 2177 a, g dbSNP:751746604
2185 2185 a, g dbSNP:765001324
2196 2196 c, t dbSNP:759372918
2197 2197 a, g dbSNP:267598786
2200 2200 c, g, t dbSNP:112766203
2204 2204 a, g dbSNP:772853110
2209 2209 a, g dbSNP:771646887
2221 2221 g, t dbSNP:568367673
2222 2222 g, t dbSNP:672601277
2224 2224 a, c dbSNP:56005131
2226 2226 a, g dbSNP:767468952
2229 2229 a, g dbSNP:767200577
2236 2236 c, t dbSNP:761351410
2245 2245 g, t dbSNP:200643089
2250 2250 g, t dbSNP:672601276
2251 2251 a, c, g dbSNP:374825099
2252 2252 c, t dbSNP:770087651
2255 2255 a, g dbSNP:746432900
2257 2257 a, c dbSNP:199634007
2258 2258 c, t dbSNP:372413776
2268 2268 c, t dbSNP:770958862
2269 2269 c, g dbSNP:747132274
2278 2278 c, g dbSNP:777673186
2280 2280 a, g dbSNP:758649719
2286 2286 c, t dbSNP:267598785
2292 2292 c, t dbSNP:752909847
2298 2298 a, g dbSNP:780047918
2299 2299 c, t dbSNP:547099198
2304 2304 a, g dbSNP:147800606
2313 2313 g, t dbSNP:750423752
2326 2326 g, t dbSNP:767464878
2332 2332 a, c dbSNP:761609256
2339 2339 c, t dbSNP:144271454
2342 2342 c, t dbSNP:55725052
2344 2344 a, g dbSNP:763449831
2348 2348 c, t dbSNP:762611418
2354 2354 c, t dbSNP:775111222
2355 2355 a, g dbSNP:371313778
2364 2364 a, g dbSNP:780813130
2371 2371 a, g dbSNP:757227327
2374 2374 a, c dbSNP:751399062
2375 2375 a, c dbSNP:763718987
2377 2377 g, t dbSNP:762446803
2388 2388 a, g dbSNP:752388408
2399 2399 a, c, g dbSNP:201575324
2402 2402 c, t dbSNP:759147254
2403 2403 a, c, g dbSNP:200687447
2406 2406 a, g dbSNP:199777072
2410 2410 a, g dbSNP:761302217
2413 2413 g, t dbSNP:773584401
2423 2423 c, t dbSNP:772229101
2431 2431 a, t dbSNP:748214188
2432 2432 g, t dbSNP:763174477
2448 2448 a, g dbSNP:372058915
2449 2449 c, t dbSNP:571114616
2453 2453 a, c, g dbSNP:672601275
2469 2469 a, g dbSNP:756992995
2470 2470 a, g dbSNP:765075551
2471 2471 c, t dbSNP:777542103
2484 2484 a, g dbSNP:757954074
2488 2488 c, t dbSNP:752228747
2489 2489 c, t dbSNP:534791840
2500 2500 -, a dbSNP:746991079
2503 2503 a, g dbSNP:60139309
2505 2505 c, g dbSNP:753419296
2511 2511 c, g dbSNP:766833304
2514 2514 a, g, t dbSNP:773815814
2517 2517 c, g dbSNP:768157853
2519 2519 a, g dbSNP:672601274
2520 2520 c, t dbSNP:557220418
2521 2521 a, g dbSNP:774579695
2525 2525 a, g dbSNP:372909322
2531 2531 a, t dbSNP:749586100
2540 2540 c, g dbSNP:775570841
2541 2541 a, g dbSNP:368519011
2544 2544 a, c dbSNP:201035051
2553 2553 a, t dbSNP:762911226
2560 2560 g, t dbSNP:55674432
2563 2563 c, t dbSNP:769932607
2566 2566 a, g dbSNP:759766897
2567 2567 c, t dbSNP:773002572
2574 2574 c, t dbSNP:771839581
2577 2577 c, t dbSNP:147545709
2578 2578 a, g dbSNP:1801267
2580 2580 a, c dbSNP:768200107
2582 2582 a, g, t dbSNP:559427764
2585 2585 a, t dbSNP:779573574
2589 2589 a, g dbSNP:755729055
2594 2594 a, g dbSNP:376391343
2599 2599 a, g dbSNP:188052243
2628 2628 a, g dbSNP:757695236
2636 2636 a, c dbSNP:752151811
2652 2652 g, t dbSNP:764679468
2667 2667 -, a dbSNP:778614771
2674 2674 c, t dbSNP:772826416
2683 2683 a, c, t dbSNP:771930534
2694 2694 a, g dbSNP:774134971
2696 2696 a, g dbSNP:763893877
2703 2703 a, g dbSNP:762858106
2704 2704 c, t dbSNP:775494607
2705 2705 a, g dbSNP:769227856
2710 2710 a, g dbSNP:568169006
2723 2723 a, t dbSNP:377152743
2727 2727 g, t dbSNP:137878450
2730 2730 a, g dbSNP:776236081
2733 2733 c, t dbSNP:770741452
2741 2741 c, t dbSNP:746595648
2742 2742 a, g dbSNP:778054451
2743 2743 c, g, t dbSNP:748639205
2750 2750 a, g dbSNP:779448929
2751 2751 c, g dbSNP:755428442
2758 2758 c, t dbSNP:753950237
2764 2764 a, t dbSNP:372307932
2767 2767 a, t dbSNP:67376798
2768 2768 c, t dbSNP:559276319
2769 2769 a, g dbSNP:763862486
2785 2785 -, a dbSNP:757037190
2785 2785 a, g dbSNP:762779297
2793 2793 a, g dbSNP:141044036
2806 2806 c, t dbSNP:765247038
2807 2807 c, t dbSNP:368617815
2809 2809 a, g dbSNP:776289153
2836 2836 a, g dbSNP:145529148
2841 2841 g, t dbSNP:757376267
2842 2842 a, t dbSNP:72547602
2852 2852 c, g dbSNP:376502495
2854 2854 a, g dbSNP:72547601
2855 2855 a, c dbSNP:201268750
2862 2862 a, c dbSNP:759562628
2865 2865 a, g dbSNP:753820482
2869 2869 c, t dbSNP:61757362
2871 2871 a, g dbSNP:760235888
2875 2875 a, c dbSNP:772544099
2898 2898 c, t dbSNP:202144771
2899 2899 g, t dbSNP:139459586
2900 2900 a, c, t dbSNP:768993607
2902 2902 c, g dbSNP:140989814
2904 2904 g, t dbSNP:1801268
2908 2908 a, g, t dbSNP:672601273
2913 2913 a, g, t dbSNP:745982505
2918 2918 c, g, t dbSNP:757509506
2919 2919 a, g dbSNP:151074666
2922 2922 g, t dbSNP:778911905
2931 2931 a, g dbSNP:754786483
2945 2945 a, c dbSNP:753873495
2946 2946 a, g dbSNP:766438205
2949 2949 c, t dbSNP:760485592
2951 2951 a, t dbSNP:749954216
2954 2954 c, t dbSNP:766878892
2955 2955 g, t dbSNP:761584058
2968 2968 a, g dbSNP:773868825
2969 2969 c, t dbSNP:545959800
2970 2970 a, g dbSNP:140114515
2982 2982 c, g dbSNP:148799944
2983 2983 c, t dbSNP:770320798
2984 2984 c, g dbSNP:746298645
2985 2985 a, g dbSNP:781348608
2988 2988 a, c, g, t dbSNP:114096998
2989 2989 c, t dbSNP:758640823
2990 2990 a, g dbSNP:749122978
2996 2996 g, t dbSNP:565115351
3006 3006 c, t dbSNP:779927189
3013 3013 a, g dbSNP:374367724
3015 3015 -, a dbSNP:753363470
3019 3019 g, t dbSNP:750312649
3031 3031 -, c dbSNP:763742591
3032 3032 a, c dbSNP:767121228
3051 3051 a, g dbSNP:370005502
3104 3104 c, t dbSNP:184161277
3106 3106 c, t dbSNP:150499371
3122 3122 -, a dbSNP:760411849
3151 3151 a, g dbSNP:747228600
3158 3158 a, g dbSNP:55938520
3162 3162 c, g dbSNP:534213499
3172 3172 c, t dbSNP:672601272
3273 3273 c, t dbSNP:56160474
3307 3307 a, g dbSNP:111295312
3327 3327 c, t dbSNP:192715981
3386 3386 a, g dbSNP:538293673
3421 3421 a, g dbSNP:569248743
3431 3431 a, t dbSNP:188501488
3434 3434 a, t dbSNP:1042480
3461 3461 c, g dbSNP:765158346
3463 3463 c, t dbSNP:754970493
3465 3465 a, c dbSNP:2635723
3475 3475 a, g dbSNP:753289746
3489 3489 -, aa dbSNP:367554694
3519 3519 c, t dbSNP:529449773
3549 3549 c, t dbSNP:567178473
3554 3554 -, c dbSNP:34856860
3555 3555 c, t dbSNP:765882514
3559 3559 a, g dbSNP:1042481
3566 3566 -, t dbSNP:528999329
3572 3572 a, g dbSNP:1042482
3586 3586 a, g dbSNP:772715720
3611 3611 a, g dbSNP:75542363
3634 3634 a, t dbSNP:535104911
3735 3735 a, t dbSNP:672601271
3767 3767 actgtgcacatat, gctgtgcacatac dbSNP:386633699
3767 3767 a, g dbSNP:291592
3779 3779 c, t dbSNP:291593
3782 3782 g, t dbSNP:137984871
3820 3820 c, t dbSNP:755469970
3899 3899 c, t dbSNP:17470762
3907 3907 g, t dbSNP:55696854
3910 3910 a, g dbSNP:672601270
3945 3945 a, g dbSNP:780504182
3960 3960 a, g dbSNP:672601269
4045 4045 a, c dbSNP:55992536
4061 4061 a, g dbSNP:41285690
4093 4093 a, g dbSNP:55921233
4124 4124 a, g dbSNP:553255417
4167 4167 c, t dbSNP:113520437
4188 4188 a, g dbSNP:570164196
4204 4204 a, t dbSNP:578078463

Target ORF information:

RefSeq Version XM_005270562
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005270562

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGGCCCCTG TGCTCAGTAA GGACTCGGCG GACATCGAGA GTATCCTGGC TTTAAATCCT 
CGAACACAAA CTCATGCAAC TCTGTGTTCC ACTTCGGCCA AGAAATTAGA CAAGAAACAT
TGGAAAAGAA ATCCTGATAA GAACTGCTTT AATTGTGAGA AGCTGGAGAA TAATTTTGAT
GACATCAAGC ACACGACTCT TGGTGAGCGA GGAGCTCTCC GAGAAGCAAT GAGATGCCTG
AAATGTGCAG ATGCCCCGTG TCAGAAGAGC TGTCCAACTA ATCTTGATAT TAAATCATTC
ATCACAAGTA TTGCAAACAA GAACTATTAT GGAGCTGCTA AGATGATATT TTCTGACAAC
CCACTTGGTC TGACTTGTGG AATGGTATGT CCAACCTCTG ATCTTTGTGT AGGTGGATGC
AATTTATATG CCACTGAAGA GGGACCCATT AATATTGGTG GATTGCAGCA ATTTGCTACT
GAGGTATTCA AAGCAATGAG TATCCCACAG ATCAGAAATC CTTCGCTGCC TCCCCCAGAA
AAAATGTCTG AAGCCTATTC TGCAAAGATT GCTCTTTTTG GTGCTGGGCC TGCAAGTATA
AGTTGTGCTT CCTTTTTGGC TCGATTGGGG TACTCTGACA TCACTATATT TGAAAAACAA
GAATATGTTG GTGGTTTAAG TACTTCTGAA ATTCCTCAGT TCCGGCTGCC GTATGATGTA
GTGAATTTTG AGATTGAGCT AATGAAGGAC CTTGGTGTAA AGATAATTTG CGGTAAAAGC
CTTTCAGTGA ATGAAATGAC TCTTAGCACT TTGAAAGAAA AAGGCTACAA AGCTGCTTTC
ATTGGAATAG GTTTGCCAGA ACCCAATAAA GATGCCATCT TCCAAGGCCT GACGCAGGAC
CAGGGGTTTT ATACATCCAA AGACTTTTTG CCACTTGTAG CCAAAGGCAG TAAAGCAGGA
ATGTGCGCCT GTCACTCTCC ATTGCCATCG ATACGGGGAG TCGTGATTGT ACTTGGAGCT
GGAGACACTG CCTTTGACTG TGCAACATCT GCTCTACGTT GTGGAGCTCG CCGTGTGTTC
ATCGTCTTCA GAAAAGGCTT TGTTAATATA AGAGCTGTCC CTGAGGAGAT GGAACTTGCT
AAGGAAGAAA AGTGTGAATT TCTGCCATTC CTGTCCCCAC GGAAGGTTAT AGTAAAAGGT
GGGAGAATTG TTGCTATGCA GTTTGTTCGG ACAGAGCAAG ATGAAACTGG AAAATGGAAT
GAAGATGAAG ATCAGATGGT CCATCTGAAA GCCGATGTGG TCATCAGTGC CTTTGGTTCA
GTTCTGAGTG ATCCTAAAGT AAAAGAAGCC TTGAGCCCTA TAAAATTTAA CAGATGGGGT
CTCCCAGAAG TAGATCCAGA AACTATGCAA ACTAGTGAAG CATGGGTATT TGCAGGTGGT
GATGTCGTTG GTTTGGCTAA CACTACAGTG GAATCGGTGA ATGATGGAAA GCAAGCTTCT
TGGTACATTC ACAAATACGT ACAGGACATT GTGACAAATG TTTCCCCCAG AATCATCCGG
GGAACCACCT CTGGCCCCAT GTATGGCCCT GGACAAAGCT CCTTTCTGAA TATTGAGCTC
ATCAGTGAGA AAACGGCTGC ATATTGGTGT CAAAGTGTCA CTGAACTAAA GGCTGACTTT
CCAGACAACA TTGTGATTGC TAGCATTATG TGCAGTTACA ATAAAAATGA CTGGACGGAA
CTTGCCAAGA AGTCTGAGGA TTCTGGAGCA GATGCCCTGG AGTTAAATTT ATCATGTCCA
CATGGCATGG GAGAAAGAGG AATGGGCCTG GCCTGTGGGC AGGATCCAGA GCTGGTGCGG
AACATCTGCC GCTGGGTTAG GCAAGCTGTT CAGATTCCTT TTTTTGCCAA GCTGACCCCA
AATGTCACTG ATATTGTGAG CATCGCAAGA GCTGCAAAGG AAGGTGGTGC CAATGGCGTT
ACAGCCACCA ACACTGTCTC AGGTCTGATG GGATTAAAAT CTGATGGCAC ACCTTGGCCA
GCAGTGGGGA TTGCAAAGCG AACTACATAT GGAGGAGTGT CTGGGACAGC AATCAGACCT
ATTGCTTTGA GAGCTGTGAC CTCCATTGCT CGTGCTCTGC CTGGATTTCC CATTTTGGCT
ACTGGTGGAA TTGACTCTGC TGAAAGTGGT CTTCAGTTTC TCCATAGTGG TGCTTCCGTC
CTCCAGGTAT GCAGTGCCAT TCAGAATCAG GATTTCACTG TGATCGAAGA CTACTGCACT
GGCCTCAAAG CCCTGCTTTA TCTGAAAAGC ATTGAAGAAC TACAAGACTG GGATGGACAG
AGTCCAGCTA CTGTGAGTCA CCAGAAAGGG AAACCAGTTC CACGTATAGC TGAACTCATG
GACAAGAAAC TGCCAAGTTT TGGACCTTAT CTGGAACAGC GCAAGAAAAT CATAGCAGAA
AACAAGATTA GACTGAAAGA ACAAAATGTA GCTTTTTCAC CACTTAAGAG AAACTGTTTT
ATCCCCAAAA GGCCTATTCC TACCATCAAG GATGTAATAG GAAAAGCACT GCAGTACCTT
GGAACATTTG GTGAATTGAG CAACGTAGAG CAAGTTGTGG CTATGATTGA TGAAGAAATG
TGTATCAACT GTGGTAAATG CTACATGACC TGTAATGATT CTGGCTACCA GGCTATACAG
TTTGATCCAG AAACCCACCT GCCCACCATA ACCGACACTT GTACAGGCTG TACTCTGTGT
CTCAGTGTTT GCCCTATTGT CGACTGCATC AAAATGGTTT CCAGGACAAC ACCTTATGAA
CCAAAGAGAG GCGTACCCTT ATCTGTGAAT CCGGTGTGTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu33083
Accession Version XM_006710397.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2670bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product dihydropyrimidine dehydrogenase [NADP(+)] isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578798495. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGGCCCCTG TGCTCAGTAA GGACTCGGCG GACATCGAGA GTATCCTGGC TTTAAATCCT 
CGAACACAAA CTCATGCAAC TCTGTGTTCC ACTTCGGCCA AGAAATTAGA CAAGAAACAT
TGGAAAAGAA ATCCTGATAA GAACTGCTTT AATTGTGAGA AGCTGGAGAA TAATTTTGAT
GACATCAAGC ACACGACTCT TGGTGAGCGA GGAGCTCTCC GAGAAGCAAT GAGATGCCTG
AAATGTGCAG ATGCCCCGTG TCAGAAGAGC TGTCCAACTA ATCTTGATAT TAAATCATTC
ATCACAAGTA TTGCAAACAA GAACTATTAT GGAGCTGCTA AGATGATATT TTCTGACAAC
CCACTTGGTC TGACTTGTGG AATGGTATGT CCAACCTCTG ATCTTTGTGT AGGTGGATGC
AATTTATATG CCACTGAAGA GGGACCCATT AATATTGGTG GATTGCAGCA ATTTGCTACT
GAGGTATTCA AAGCAATGAG TATCCCACAG ATCAGAAATC CTTCGCTGCC TCCCCCAGAA
AAAATGTCTG AAGCCTATTC TGCAAAGATT GCTCTTTTTG GTGCTGGGCC TGCAAGTATA
AGTTGTGCTT CCTTTTTGGC TCGATTGGGG TACTCTGACA TCACTATATT TGAAAAACAA
GAATATGTTG GTGGTTTAAG TACTTCTGAA ATTCCTCAGT TCCGGCTGCC GTATGATGTA
GTGAATTTTG AGATTGAGCT AATGAAGGAC CTTGGTGTAA AGATAATTTG CGGTAAAAGC
CTTTCAGTGA ATGAAATGAC TCTTAGCACT TTGAAAGAAA AAGGCTACAA AGCTGCTTTC
ATTGGAATAG GTTTGCCAGA ACCCAATAAA GATGCCATCT TCCAAGGCCT GACGCAGGAC
CAGGGGTTTT ATACATCCAA AGACTTTTTG CCACTTGTAG CCAAAGGCAG TAAAGCAGGA
ATGTGCGCCT GTCACTCTCC ATTGCCATCG ATACGGGGAG TCGTGATTGT ACTTGGAGCT
GGAGACACTG CCTTTGACTG TGCAACATCT GCTCTACGTT GTGGAGCTCG CCGTGTGTTC
ATCGTCTTCA GAAAAGGCTT TGTTAATATA AGAGCTGTCC CTGAGGAGAT GGAACTTGCT
AAGGAAGAAA AGTGTGAATT TCTGCCATTC CTGTCCCCAC GGAAGGTTAT AGTAAAAGGT
GGGAGAATTG TTGCTATGCA GTTTGTTCGG ACAGAGCAAG ATGAAACTGG AAAATGGAAT
GAAGATGAAG ATCAGATGGT CCATCTGAAA GCCGATGTGG TCATCAGTGC CTTTGGTTCA
GTTCTGAGTG ATCCTAAAGT AAAAGAAGCC TTGAGCCCTA TAAAATTTAA CAGATGGGGT
CTCCCAGAAG TAGATCCAGA AACTATGCAA ACTAGTGAAG CATGGGTATT TGCAGGTGGT
GATGTCGTTG GTTTGGCTAA CACTACAGTG GAATCGGTGA ATGATGGAAA GCAAGCTTCT
TGGTACATTC ACAAATACGT ACAGTCACAA TATGGAGCTT CCGTTTCTGC CAAGCCTGAA
CTACCCCTCT TTTACACTCC TATTGATCTG GTGGACATTA GTGTAGAAAT GGCCGGATTG
AAGTTTATAA ATCCTTTTGG TCTTGCTAGC GCAACTCCAG CCACCAGCAC ATCAATGATT
CGAAGAGCTT TTGAAGCTGG ATGGGGTTTT GCCCTCACCA AAACTTTCTC TCTTGATAAG
GACATTGTGA CAAATGTTTC CCCCAGAATC ATCCGGGGAA CCACCTCTGG CCCCATGTAT
GGCCCTGGAC AAAGCTCCTT TCTGAATATT GAGCTCATCA GTGAGAAAAC GGCTGCATAT
TGGTGTCAAA GTGTCACTGA ACTAAAGGCT GACTTTCCAG ACAACATTGT GATTGCTAGC
ATTATGTGCA GTTACAATAA AAATGACTGG ACGGAACTTG CCAAGAAGTC TGAGGATTCT
GGAGCAGATG CCCTGGAGTT AAATTTATCA TGTCCACATG GCATGGGAGA AAGAGGAATG
GGCCTGGCCT GTGGGCAGGA TCCAGAGCTG GTGCGGAACA TCTGCCGCTG GGTTAGGCAA
GCTGTTCAGA TTCCTTTTTT TGCCAAGCTG ACCCCAAATG TCACTGATAT TGTGAGCATC
GCAAGAGCTG CAAAGGAAGG TGGTGCCAAT GGCGTTACAG CCACCAACAC TGTCTCAGGT
CTGATGGGAT TAAAATCTGA TGGCACACCT TGGCCAGCAG TGGGGATTGC AAAGCGAACT
ACATATGGAG GAGTGTCTGG GACAGCAATC AGACCTATTG CTTTGAGAGC TGTGACCTCC
ATTGCTCGTG CTCTGCCTGG ATTTCCCATT TTGGCTACTG GTGGAATTGA CTCTGCTGAA
AGTGGTCTTC AGTTTCTCCA TAGTGGTGCT TCCGTCCTCC AGGTATGCAG TGCCATTCAG
AATCAGGATT TCACTGTGAT CGAAGACTAC TGCACTGGCC TCAAAGCCCT GCTTTATCTG
AAAAGCATTG AAGAACTACA AGACTGGGAT GGACAGAGTC CAGCTACTGT GAGTCACCAG
AAAGGGAAAC CAGTTCCACG TATAGCTGAA CTCATGGACA AGGAAACACA GTGCCTCCTG
GATGTGATTT CTTCAGTGGA CTCTTTCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_006710460.1
CDS138..2807
Misc Feature(1)294..1676(+)
Misc Feature(2)309..635(+)
Misc Feature(3)717..>851(+)
Misc Feature(4)1731..2639(+)
Misc Feature(5)1734..2675(+)
Misc Feature(6)1791..2612(+)
Misc Feature(7)1857..2348(+)
Misc Feature(8)1857..2348(+)
Misc Feature(9)1962..2348(+)
Translation
Position Chain Variation Link
1 1 c, g dbSNP:529162686
28 28 c, t dbSNP:534300645
39 39 a, t dbSNP:571741157
46 46 a, g dbSNP:551486678
50 50 a, t dbSNP:531689464
52 52 c, t dbSNP:569146754
63 63 a, g dbSNP:550078641
89 89 a, g dbSNP:758152525
92 92 g, t dbSNP:752581618
94 94 a, c dbSNP:765165101
95 95 a, g dbSNP:754506010
96 96 c, g dbSNP:529923798
120 120 c, g dbSNP:577136443
125 125 g, t dbSNP:760379014
138 138 a, c dbSNP:772950053
140 140 a, g dbSNP:768020954
144 144 c, t dbSNP:762198241
150 150 c, t dbSNP:772097379
158 158 a, g dbSNP:774730464
160 160 a, t dbSNP:769190350
167 167 g, t dbSNP:749369964
173 173 c, g dbSNP:376273539
174 174 a, g dbSNP:769820114
182 182 a, c, t dbSNP:267598790
183 183 c, g dbSNP:150036960
184 184 c, t dbSNP:764555085
185 185 a, g dbSNP:763165014
196 196 c, g dbSNP:753217888
198 198 c, t dbSNP:72549310
199 199 a, g dbSNP:80081766
210 210 c, t dbSNP:775601164
211 211 a, c dbSNP:776662759
213 213 a, g dbSNP:766635900
216 216 a, t dbSNP:770229152
222 222 c, t dbSNP:1801265
223 223 a, g dbSNP:528768620
228 228 a, g dbSNP:768501828
232 232 c, t dbSNP:748974194
233 233 a, g dbSNP:775622568
237 237 a, g dbSNP:769847078
254 254 a, g dbSNP:745409341
264 264 a, g dbSNP:780873985
274 274 a, g dbSNP:756684474
278 278 a, g dbSNP:746681994
279 279 a, g dbSNP:777238016
287 287 c, t dbSNP:370036611
295 295 a, g dbSNP:757958938
302 302 a, g dbSNP:139126323
314 314 c, t dbSNP:779270411
323 323 c, t dbSNP:181215161
324 324 a, g dbSNP:367619008
331 331 c, g, t dbSNP:371587702
345 345 c, t dbSNP:141597515
346 346 a, g dbSNP:767818267
355 355 g, t dbSNP:762102298
357 357 c, t dbSNP:189768576
364 364 c, t dbSNP:765131182
366 366 a, g dbSNP:527580106
369 369 a, t dbSNP:776692894
390 390 a, g dbSNP:757342874
394 394 c, t dbSNP:568132506
395 395 a, g, t dbSNP:201841475
397 397 g, t dbSNP:528152707
402 402 a, t dbSNP:672601289
406 406 g, t dbSNP:672601288
411 411 c, g dbSNP:143986398
413 413 a, c dbSNP:766389732
415 415 c, g dbSNP:760553268
423 423 c, g dbSNP:773159364
424 424 a, t dbSNP:771573678
425 425 c, t dbSNP:761254577
427 427 c, t dbSNP:375990187
432 432 -, tcat dbSNP:72549309
436 436 -, tcat dbSNP:539032572
437 437 c, t dbSNP:774047246
447 447 a, g dbSNP:768288280
449 449 g, t dbSNP:749699298
450 450 a, g dbSNP:150385342
452 452 a, g dbSNP:770144122
461 461 a, c dbSNP:762430779
469 469 a, g dbSNP:762533012
479 479 g, t dbSNP:370615432
480 480 a, g dbSNP:141462178
482 482 c, g dbSNP:377169736
494 494 c, t dbSNP:777348913
496 496 a, g dbSNP:771534236
500 500 a, c dbSNP:747135235
504 504 a, g dbSNP:778022685
516 516 a, g dbSNP:758514990
523 523 g, t dbSNP:748320430
530 530 a, g dbSNP:779135187
531 531 a, t dbSNP:538336580
532 532 c, t dbSNP:750224169
547 547 c, t dbSNP:767482279
551 551 g, t dbSNP:757163217
554 554 a, g dbSNP:751448860
561 561 g, t dbSNP:763623595
568 568 c, g dbSNP:762468894
569 569 c, t dbSNP:775065182
578 578 a, g dbSNP:764939839
581 581 a, g dbSNP:56108357
584 584 c, g dbSNP:759858246
588 588 a, g dbSNP:200562975
600 600 c, t dbSNP:201443458
604 604 a, g dbSNP:536577604
611 611 c, t dbSNP:190771411
626 626 a, c dbSNP:368970772
633 633 a, g dbSNP:2297595
634 634 c, t dbSNP:763061658
635 635 a, g dbSNP:139834141
637 637 g, t dbSNP:775526810
644 644 a, g dbSNP:765252243
658 658 c, g dbSNP:374827081
661 661 c, g, t dbSNP:371792178
662 662 a, g dbSNP:6670886
668 668 g, t dbSNP:774411340
670 670 a, c dbSNP:768680499
679 679 a, c dbSNP:672601287
681 681 -, a dbSNP:754785410
681 681 a, g dbSNP:748853941
682 682 a, t dbSNP:779728902
690 690 a, g dbSNP:374531732
693 693 g, t dbSNP:755645831
694 694 a, g dbSNP:115232898
705 705 a, g dbSNP:368152149
707 707 c, t dbSNP:149843476
718 718 a, g, t dbSNP:751841116
726 726 a, c dbSNP:764635955
728 728 c, t dbSNP:758927521
729 729 c, g dbSNP:753166888
730 730 a, c dbSNP:765309287
732 732 a, g dbSNP:759479759
733 733 a, g dbSNP:776973423
734 734 c, t dbSNP:766503499
738 738 a, c dbSNP:72549308
743 743 c, t dbSNP:773991224
749 749 c, g dbSNP:768519000
756 756 a, g dbSNP:749269410
758 758 a, g, t dbSNP:769440759
760 760 a, g, t dbSNP:376073289
769 769 a, g dbSNP:72549307
776 776 c, t dbSNP:190048823
783 783 a, g dbSNP:778141885
790 790 a, g dbSNP:758699471
793 793 a, g dbSNP:781184141
798 798 g, t dbSNP:146170505
807 807 g, t dbSNP:755155824
809 809 c, t dbSNP:753828034
840 840 c, t dbSNP:1801266
841 841 a, g dbSNP:755416212
842 842 a, g dbSNP:754317478
846 846 c, t dbSNP:267598789
847 847 c, t dbSNP:780025995
848 848 a, g dbSNP:139863300
852 852 a, g dbSNP:750687600
870 870 a, g dbSNP:767836989
876 876 a, c, t dbSNP:376128878
891 891 g, t dbSNP:765034707
893 893 c, t dbSNP:6675198
905 905 g, t dbSNP:556933127
907 907 a, g dbSNP:764945792
908 908 c, t dbSNP:754745863
909 909 a, g dbSNP:141726921
912 912 a, g dbSNP:45589337
915 915 a, g dbSNP:760222167
917 917 c, t dbSNP:772684506
932 932 a, g dbSNP:766962931
939 939 c, g dbSNP:761479700
940 940 a, t dbSNP:773983635
943 943 a, g dbSNP:768915005
944 944 c, t dbSNP:200702346
946 946 c, g dbSNP:775926386
953 953 a, g dbSNP:770391936
959 959 -, a dbSNP:749881640
977 977 c, t dbSNP:557212505
978 978 a, t dbSNP:746329786
979 979 c, t dbSNP:369103276
980 980 c, t dbSNP:781454573
988 988 a, g, t dbSNP:777220476
991 991 c, t dbSNP:771194906
993 993 c, t dbSNP:751113340
1005 1005 a, g dbSNP:146356975
1006 1006 a, g dbSNP:672601285
1007 1007 a, t dbSNP:777902288
1009 1009 a, g dbSNP:772320654
1012 1012 c, t dbSNP:748266854
1013 1013 c, t dbSNP:187484874
1014 1014 a, c dbSNP:779925747
1020 1020 -, c dbSNP:772507658
1024 1024 a, g dbSNP:672601284
1030 1030 a, c, t dbSNP:143879757
1031 1031 a, g dbSNP:61758443
1040 1040 a, g, t dbSNP:751049055
1047 1047 c, t dbSNP:183105782
1059 1059 -, g dbSNP:759965732
1064 1064 c, t dbSNP:762699533
1066 1066 c, t dbSNP:150437414
1071 1071 c, t dbSNP:145112791
1075 1075 c, t dbSNP:759967863
1084 1084 g, t dbSNP:749157068
1087 1087 a, g dbSNP:777347164
1092 1092 a, g dbSNP:771536388
1103 1103 c, t dbSNP:768834079
1104 1104 a, g dbSNP:201018345
1112 1112 c, t dbSNP:141376128
1113 1113 c, t dbSNP:770566506
1114 1114 c, t dbSNP:575763449
1116 1116 c, t dbSNP:369575517
1126 1126 c, t dbSNP:777560627
1131 1131 c, t dbSNP:757994597
1132 1132 a, g dbSNP:747633945
1135 1135 c, g dbSNP:778760295
1139 1139 a, c, t dbSNP:753504491
1140 1140 a, g, t dbSNP:72549306
1144 1144 c, t dbSNP:756372042
1145 1145 a, t dbSNP:750994754
1148 1148 a, t dbSNP:767903251
1151 1151 g, t dbSNP:761991197
1157 1157 g, t dbSNP:774390439
1158 1158 a, g dbSNP:764111543
1161 1161 a, g dbSNP:183385770
1162 1162 a, g dbSNP:769709846
1166 1166 c, t dbSNP:770818300
1172 1172 c, t dbSNP:1042478
1177 1177 a, g dbSNP:746777181
1181 1181 a, g dbSNP:773243157
1185 1185 c, t dbSNP:771885007
1191 1191 -, c dbSNP:771024192
1191 1191 c, g dbSNP:190577302
1194 1194 c, t dbSNP:143154602
1195 1195 a, g dbSNP:778601245
1204 1204 c, t dbSNP:754467630
1206 1206 c, t dbSNP:748958293
1207 1207 a, g dbSNP:377143350
1209 1209 c, t dbSNP:779557503
1210 1210 a, g dbSNP:573299212
1211 1211 a, t dbSNP:1042479
1213 1213 a, t dbSNP:750721736
1217 1217 c, g dbSNP:745704371
1218 1218 a, g dbSNP:768117152
1220 1220 c, t dbSNP:372369973
1221 1221 a, g dbSNP:752020412
1226 1226 c, t dbSNP:764173823
1229 1229 a, c dbSNP:763008163
1234 1234 g, t dbSNP:752985272
1245 1245 a, g dbSNP:72549305
1246 1246 -, ta dbSNP:749571474
1246 1246 c, t dbSNP:760570391
1254 1254 a, g dbSNP:772906420
1257 1257 c, t dbSNP:201785202
1262 1262 a, g dbSNP:761850800
1266 1266 a, g dbSNP:144935781
1269 1269 c, g dbSNP:201648613
1271 1271 a, g dbSNP:1126741
1277 1277 c, t dbSNP:150759598
1292 1292 -, tg dbSNP:769925158
1293 1293 -, catcac dbSNP:777662767
1293 1293 g, t dbSNP:78060119
1294 1294 -, c dbSNP:748023289
1294 1294 a, t dbSNP:576409484
1304 1304 a, g dbSNP:753482702
1306 1306 c, t dbSNP:754028972
1307 1307 a, c dbSNP:767437717
1317 1317 a, c, t dbSNP:140602333
1318 1318 g, t dbSNP:143815742
1326 1326 a, g dbSNP:762598766
1341 1341 -, a dbSNP:781098341
1346 1346 c, t dbSNP:267598788
1348 1348 g, t dbSNP:774883578
1350 1350 a, g dbSNP:769306962
1351 1351 c, t dbSNP:745512069
1353 1353 a, g dbSNP:780885126
1355 1355 a, g dbSNP:61622928
1365 1365 a, c, t dbSNP:528430685
1366 1366 a, g dbSNP:199646142
1373 1373 a, g dbSNP:56038477
1378 1378 a, g dbSNP:778867644
1380 1380 g, t dbSNP:755031341
1391 1391 a, g dbSNP:141370079
1397 1397 a, t dbSNP:200064537
1401 1401 c, g dbSNP:766700777
1402 1402 a, g dbSNP:757155354
1408 1408 a, t dbSNP:751374989
1409 1409 a, c, t dbSNP:532341730
1414 1414 c, t dbSNP:751340819
1415 1415 a, g, t dbSNP:764666241
1416 1416 g, t dbSNP:759082282
1417 1417 c, t dbSNP:200693895
1430 1430 c, t dbSNP:770549765
1431 1431 a, g dbSNP:142512579
1433 1433 c, t dbSNP:773600085
1434 1434 c, g dbSNP:772358811
1437 1437 c, g dbSNP:748620513
1438 1438 c, t dbSNP:779465366
1438 1438 -, t dbSNP:754978663
1444 1444 a, c, g dbSNP:370569731
1445 1445 a, t dbSNP:749354734
1448 1448 c, t dbSNP:780469489
1451 1451 g, t dbSNP:186169810
1463 1463 a, g dbSNP:750632457
1471 1471 c, g dbSNP:763984510
1472 1472 g, t dbSNP:758154006
1474 1474 a, c dbSNP:200709381
1481 1481 a, g dbSNP:752516372
1486 1486 c, g, t dbSNP:72975710
1494 1494 c, t dbSNP:753710779
1495 1495 a, c, g dbSNP:144395748
1506 1506 a, g dbSNP:750147471
1508 1508 c, t dbSNP:57918000
1516 1516 -, g dbSNP:779948148
1528 1528 c, t dbSNP:370707404
1529 1529 a, g dbSNP:373724295
1533 1533 c, t dbSNP:774799003
1540 1540 a, c dbSNP:199549923
1543 1543 c, t dbSNP:763557204
1552 1552 a, g dbSNP:776082092
1553 1553 c, t dbSNP:770056548
1575 1575 a, g dbSNP:745911874
1583 1583 c, t dbSNP:376470184
1584 1584 a, g dbSNP:141439344
1592 1592 a, g dbSNP:560012397
1593 1593 a, g dbSNP:747161261
1602 1602 a, g dbSNP:778776264
1612 1612 c, t dbSNP:72549304
1613 1613 a, g dbSNP:753835178
1618 1618 a, g dbSNP:779967271
1621 1621 a, g dbSNP:111858276
1631 1631 a, g, t dbSNP:116364703
1635 1635 g, t dbSNP:766885021
1642 1642 a, g dbSNP:761555670
1644 1644 a, g dbSNP:751104498
1655 1655 c, t dbSNP:201166313
1656 1656 a, g dbSNP:138391898
1658 1658 a, t dbSNP:373838132
1661 1661 a, g dbSNP:775930761
1675 1675 c, t dbSNP:760663364
1676 1676 c, t dbSNP:773519625
1678 1678 c, t dbSNP:772264512
1679 1679 c, t dbSNP:748323941
1680 1680 a, g dbSNP:148994843
1684 1684 a, c dbSNP:769514867
1689 1689 a, g dbSNP:745833535
1691 1691 a, g dbSNP:369465750
1692 1692 c, t dbSNP:672601282
1697 1697 a, g dbSNP:138979515
1709 1709 g, t dbSNP:777368221
1710 1710 c, t dbSNP:758154803
1712 1712 c, t dbSNP:752329473
1714 1714 c, g dbSNP:190951787
1724 1724 c, t dbSNP:140125782
1738 1738 a, g dbSNP:1801158
1745 1745 a, c dbSNP:766761199
1751 1751 c, t dbSNP:760853559
1752 1752 a, c, g dbSNP:142619737
1754 1754 a, g dbSNP:762029458
1755 1755 a, t dbSNP:774500505
1764 1764 a, g dbSNP:1801159
1772 1772 c, t dbSNP:759247778
1782 1782 c, g dbSNP:140039091
1787 1787 c, t dbSNP:149101842
1788 1788 a, g, t dbSNP:777425216
1791 1791 a, g dbSNP:771648776
1795 1795 c, t dbSNP:747858350
1799 1799 c, t dbSNP:778701084
1803 1803 a, c dbSNP:755407188
1807 1807 c, t dbSNP:754125729
1808 1808 a, g dbSNP:780421257
1812 1812 a, g dbSNP:756613407
1816 1816 a, g, t dbSNP:55886062
1819 1819 a, g, t dbSNP:201615754
1821 1821 a, c dbSNP:761869860
1823 1823 a, t dbSNP:751848058
1825 1825 c, t dbSNP:764270260
1829 1829 a, t dbSNP:759424419
1834 1834 c, g dbSNP:776321529
1838 1838 a, g, t dbSNP:148372305
1855 1855 c, t dbSNP:558354142
1862 1862 c, t dbSNP:538115714
1863 1863 g, t dbSNP:747627716
1864 1864 -, t dbSNP:764584080
1870 1870 c, t dbSNP:778754188
1880 1880 c, t dbSNP:555178721
1894 1894 c, t dbSNP:374527058
1907 1907 -, tc dbSNP:768130933
1911 1911 c, t dbSNP:59086055
1912 1912 a, g dbSNP:138616379
1914 1914 a, g dbSNP:145773863
1915 1915 a, g dbSNP:758489611
1918 1918 a, c dbSNP:759249769
1920 1920 a, g dbSNP:765465250
1924 1924 c, g dbSNP:756020314
1933 1933 c, t dbSNP:147601618
1934 1934 c, g dbSNP:767376585
1945 1945 a, g dbSNP:371258350
1955 1955 c, g dbSNP:774290851
1963 1963 a, c dbSNP:763572567
1969 1969 a, t dbSNP:762523739
1973 1973 a, c dbSNP:151216654
1974 1974 a, c, g dbSNP:769466648
1983 1983 a, c dbSNP:368146607
1986 1986 a, g dbSNP:776984091
1987 1987 c, t dbSNP:753707032
1988 1988 a, g dbSNP:747571447
1994 1994 a, g dbSNP:778338661
1996 1996 a, g, t dbSNP:748235192
2002 2002 a, g dbSNP:201433243
2033 2033 c, t dbSNP:17376848
2035 2035 -, c dbSNP:72549303
2038 2038 a, g dbSNP:200296941
2042 2042 c, g, t dbSNP:3918289
2043 2043 a, c dbSNP:55971861
2057 2057 c, t dbSNP:758391723
2065 2065 g, t dbSNP:752518145
2068 2068 a, g dbSNP:548783838
2074 2074 a, g dbSNP:780120302
2087 2087 c, g dbSNP:753527420
2089 2089 c, t dbSNP:765990958
2090 2090 a, g dbSNP:267598787
2100 2100 a, g dbSNP:529019871
2101 2101 a, g dbSNP:773652644
2127 2127 g, t dbSNP:138545885
2128 2128 c, t dbSNP:749982106
2139 2139 a, c dbSNP:767986711
2144 2144 a, t dbSNP:762083671
2152 2152 c, g dbSNP:763784786
2158 2158 a, g dbSNP:137999090
2160 2160 a, g dbSNP:763506271
2164 2164 a, g dbSNP:575853463
2169 2169 a, g dbSNP:769696395
2173 2173 a, g dbSNP:746115989
2176 2176 c, t dbSNP:187713395
2180 2180 -, cctggcctgtgggcag dbSNP:773499329
2186 2186 c, g dbSNP:183475941
2188 2188 g, t dbSNP:747872037
2197 2197 a, c dbSNP:755692084
2208 2208 g, t dbSNP:202212118
2211 2211 c, t dbSNP:538703919
2212 2212 a, g dbSNP:375436137
2217 2217 a, g dbSNP:756890859
2223 2223 c, t dbSNP:751190912
2224 2224 a, g dbSNP:778298325
2228 2228 a, c, g dbSNP:753296078
2234 2234 g, t dbSNP:765640386
2238 2238 a, g dbSNP:760038956
2249 2249 -, t dbSNP:770063428
2252 2252 a, t dbSNP:753891721
2254 2254 g, t dbSNP:766411970
2270 2270 a, c dbSNP:768101874
2274 2274 a, g dbSNP:773407491
2276 2276 a, t dbSNP:768507975
2278 2278 c, t dbSNP:569661196
2282 2282 c, t dbSNP:775551741
2294 2294 c, t dbSNP:769645315
2297 2297 a, c, t dbSNP:780572158
2298 2298 a, g dbSNP:145548112
2323 2323 c, t dbSNP:146529561
2330 2330 c, t dbSNP:139543981
2331 2331 a, g dbSNP:1801160
2332 2332 g, t dbSNP:60511679
2347 2347 c, t dbSNP:570122671
2349 2349 c, g dbSNP:368327291
2358 2358 c, g dbSNP:767547827
2366 2366 a, g dbSNP:757475393
2393 2393 a, g dbSNP:751746604
2401 2401 a, g dbSNP:765001324
2412 2412 c, t dbSNP:759372918
2413 2413 a, g dbSNP:267598786
2416 2416 c, g, t dbSNP:112766203
2420 2420 a, g dbSNP:772853110
2425 2425 a, g dbSNP:771646887
2437 2437 g, t dbSNP:568367673
2438 2438 g, t dbSNP:672601277
2440 2440 a, c dbSNP:56005131
2442 2442 a, g dbSNP:767468952
2445 2445 a, g dbSNP:767200577
2452 2452 c, t dbSNP:761351410
2461 2461 g, t dbSNP:200643089
2466 2466 g, t dbSNP:672601276
2467 2467 a, c, g dbSNP:374825099
2468 2468 c, t dbSNP:770087651
2471 2471 a, g dbSNP:746432900
2473 2473 a, c dbSNP:199634007
2474 2474 c, t dbSNP:372413776
2484 2484 c, t dbSNP:770958862
2485 2485 c, g dbSNP:747132274
2494 2494 c, g dbSNP:777673186
2496 2496 a, g dbSNP:758649719
2502 2502 c, t dbSNP:267598785
2508 2508 c, t dbSNP:752909847
2514 2514 a, g dbSNP:780047918
2515 2515 c, t dbSNP:547099198
2520 2520 a, g dbSNP:147800606
2529 2529 g, t dbSNP:750423752
2542 2542 g, t dbSNP:767464878
2548 2548 a, c dbSNP:761609256
2555 2555 c, t dbSNP:144271454
2558 2558 c, t dbSNP:55725052
2560 2560 a, g dbSNP:763449831
2564 2564 c, t dbSNP:762611418
2570 2570 c, t dbSNP:775111222
2571 2571 a, g dbSNP:371313778
2580 2580 a, g dbSNP:780813130
2587 2587 a, g dbSNP:757227327
2590 2590 a, c dbSNP:751399062
2591 2591 a, c dbSNP:763718987
2593 2593 g, t dbSNP:762446803
2604 2604 a, g dbSNP:752388408
2615 2615 a, c, g dbSNP:201575324
2618 2618 c, t dbSNP:759147254
2619 2619 a, c, g dbSNP:200687447
2622 2622 a, g dbSNP:199777072
2626 2626 a, g dbSNP:761302217
2629 2629 g, t dbSNP:773584401
2639 2639 c, t dbSNP:772229101
2647 2647 a, t dbSNP:748214188
2648 2648 g, t dbSNP:763174477
2664 2664 a, g dbSNP:372058915
2665 2665 c, t dbSNP:571114616
2669 2669 a, c, g dbSNP:672601275
2685 2685 a, g dbSNP:756992995
2686 2686 a, g dbSNP:765075551
2687 2687 c, t dbSNP:777542103
2700 2700 a, g dbSNP:757954074
2704 2704 c, t dbSNP:752228747
2705 2705 c, t dbSNP:534791840
2716 2716 -, a dbSNP:746991079
2719 2719 a, g dbSNP:60139309
2721 2721 c, g dbSNP:753419296
2727 2727 c, g dbSNP:766833304
2730 2730 a, g, t dbSNP:773815814
2733 2733 c, g dbSNP:768157853
2735 2735 a, g dbSNP:672601274
2736 2736 c, t dbSNP:557220418
2737 2737 a, g dbSNP:774579695
2741 2741 a, g dbSNP:372909322
2747 2747 a, t dbSNP:749586100
2756 2756 c, g dbSNP:775570841
2757 2757 a, g dbSNP:368519011
2760 2760 a, g dbSNP:759285661
2763 2763 a, t dbSNP:568403376
2789 2789 c, t dbSNP:372148648
2790 2790 g, t dbSNP:776604742
2838 2838 c, t dbSNP:548510406
2848 2848 c, g dbSNP:139359364
2862 2862 a, g dbSNP:770793295
2863 2863 a, g dbSNP:566771693
2875 2875 a, g dbSNP:746475005
2886 2886 g, t dbSNP:182373190
2896 2896 a, g dbSNP:4950023
2906 2906 a, g dbSNP:555880288
2944 2944 a, g dbSNP:61786272
2947 2947 c, t dbSNP:763733915
2961 2961 a, g dbSNP:550812312
2964 2964 g, t dbSNP:72967809

Target ORF information:

RefSeq Version XM_006710397
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006710397

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGGCCCCTG TGCTCAGTAA GGACTCGGCG GACATCGAGA GTATCCTGGC TTTAAATCCT 
CGAACACAAA CTCATGCAAC TCTGTGTTCC ACTTCGGCCA AGAAATTAGA CAAGAAACAT
TGGAAAAGAA ATCCTGATAA GAACTGCTTT AATTGTGAGA AGCTGGAGAA TAATTTTGAT
GACATCAAGC ACACGACTCT TGGTGAGCGA GGAGCTCTCC GAGAAGCAAT GAGATGCCTG
AAATGTGCAG ATGCCCCGTG TCAGAAGAGC TGTCCAACTA ATCTTGATAT TAAATCATTC
ATCACAAGTA TTGCAAACAA GAACTATTAT GGAGCTGCTA AGATGATATT TTCTGACAAC
CCACTTGGTC TGACTTGTGG AATGGTATGT CCAACCTCTG ATCTTTGTGT AGGTGGATGC
AATTTATATG CCACTGAAGA GGGACCCATT AATATTGGTG GATTGCAGCA ATTTGCTACT
GAGGTATTCA AAGCAATGAG TATCCCACAG ATCAGAAATC CTTCGCTGCC TCCCCCAGAA
AAAATGTCTG AAGCCTATTC TGCAAAGATT GCTCTTTTTG GTGCTGGGCC TGCAAGTATA
AGTTGTGCTT CCTTTTTGGC TCGATTGGGG TACTCTGACA TCACTATATT TGAAAAACAA
GAATATGTTG GTGGTTTAAG TACTTCTGAA ATTCCTCAGT TCCGGCTGCC GTATGATGTA
GTGAATTTTG AGATTGAGCT AATGAAGGAC CTTGGTGTAA AGATAATTTG CGGTAAAAGC
CTTTCAGTGA ATGAAATGAC TCTTAGCACT TTGAAAGAAA AAGGCTACAA AGCTGCTTTC
ATTGGAATAG GTTTGCCAGA ACCCAATAAA GATGCCATCT TCCAAGGCCT GACGCAGGAC
CAGGGGTTTT ATACATCCAA AGACTTTTTG CCACTTGTAG CCAAAGGCAG TAAAGCAGGA
ATGTGCGCCT GTCACTCTCC ATTGCCATCG ATACGGGGAG TCGTGATTGT ACTTGGAGCT
GGAGACACTG CCTTTGACTG TGCAACATCT GCTCTACGTT GTGGAGCTCG CCGTGTGTTC
ATCGTCTTCA GAAAAGGCTT TGTTAATATA AGAGCTGTCC CTGAGGAGAT GGAACTTGCT
AAGGAAGAAA AGTGTGAATT TCTGCCATTC CTGTCCCCAC GGAAGGTTAT AGTAAAAGGT
GGGAGAATTG TTGCTATGCA GTTTGTTCGG ACAGAGCAAG ATGAAACTGG AAAATGGAAT
GAAGATGAAG ATCAGATGGT CCATCTGAAA GCCGATGTGG TCATCAGTGC CTTTGGTTCA
GTTCTGAGTG ATCCTAAAGT AAAAGAAGCC TTGAGCCCTA TAAAATTTAA CAGATGGGGT
CTCCCAGAAG TAGATCCAGA AACTATGCAA ACTAGTGAAG CATGGGTATT TGCAGGTGGT
GATGTCGTTG GTTTGGCTAA CACTACAGTG GAATCGGTGA ATGATGGAAA GCAAGCTTCT
TGGTACATTC ACAAATACGT ACAGTCACAA TATGGAGCTT CCGTTTCTGC CAAGCCTGAA
CTACCCCTCT TTTACACTCC TATTGATCTG GTGGACATTA GTGTAGAAAT GGCCGGATTG
AAGTTTATAA ATCCTTTTGG TCTTGCTAGC GCAACTCCAG CCACCAGCAC ATCAATGATT
CGAAGAGCTT TTGAAGCTGG ATGGGGTTTT GCCCTCACCA AAACTTTCTC TCTTGATAAG
GACATTGTGA CAAATGTTTC CCCCAGAATC ATCCGGGGAA CCACCTCTGG CCCCATGTAT
GGCCCTGGAC AAAGCTCCTT TCTGAATATT GAGCTCATCA GTGAGAAAAC GGCTGCATAT
TGGTGTCAAA GTGTCACTGA ACTAAAGGCT GACTTTCCAG ACAACATTGT GATTGCTAGC
ATTATGTGCA GTTACAATAA AAATGACTGG ACGGAACTTG CCAAGAAGTC TGAGGATTCT
GGAGCAGATG CCCTGGAGTT AAATTTATCA TGTCCACATG GCATGGGAGA AAGAGGAATG
GGCCTGGCCT GTGGGCAGGA TCCAGAGCTG GTGCGGAACA TCTGCCGCTG GGTTAGGCAA
GCTGTTCAGA TTCCTTTTTT TGCCAAGCTG ACCCCAAATG TCACTGATAT TGTGAGCATC
GCAAGAGCTG CAAAGGAAGG TGGTGCCAAT GGCGTTACAG CCACCAACAC TGTCTCAGGT
CTGATGGGAT TAAAATCTGA TGGCACACCT TGGCCAGCAG TGGGGATTGC AAAGCGAACT
ACATATGGAG GAGTGTCTGG GACAGCAATC AGACCTATTG CTTTGAGAGC TGTGACCTCC
ATTGCTCGTG CTCTGCCTGG ATTTCCCATT TTGGCTACTG GTGGAATTGA CTCTGCTGAA
AGTGGTCTTC AGTTTCTCCA TAGTGGTGCT TCCGTCCTCC AGGTATGCAG TGCCATTCAG
AATCAGGATT TCACTGTGAT CGAAGACTAC TGCACTGGCC TCAAAGCCCT GCTTTATCTG
AAAAGCATTG AAGAACTACA AGACTGGGAT GGACAGAGTC CAGCTACTGT GAGTCACCAG
AAAGGGAAAC CAGTTCCACG TATAGCTGAA CTCATGGACA AGGAAACACA GTGCCTCCTG
GATGTGATTT CTTCAGTGGA CTCTTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19551
Accession Version NM_000110.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3078bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product dihydropyrimidine dehydrogenase [NADP(+)] isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA721123.1, U20938.1 and AI124948.1. This sequence is a reference standard in the RefSeqGene project. On Dec 25, 2006 this sequence version replaced gi:4557874. Summary: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U20938.1, U09178.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
ATGGCCCCTG TGCTCAGTAA GGACTCGGCG GACATCGAGA GTATCCTGGC TTTAAATCCT 
CGAACACAAA CTCATGCAAC TCTGTGTTCC ACTTCGGCCA AGAAATTAGA CAAGAAACAT
TGGAAAAGAA ATCCTGATAA GAACTGCTTT AATTGTGAGA AGCTGGAGAA TAATTTTGAT
GACATCAAGC ACACGACTCT TGGTGAGCGA GGAGCTCTCC GAGAAGCAAT GAGATGCCTG
AAATGTGCAG ATGCCCCGTG TCAGAAGAGC TGTCCAACTA ATCTTGATAT TAAATCATTC
ATCACAAGTA TTGCAAACAA GAACTATTAT GGAGCTGCTA AGATGATATT TTCTGACAAC
CCACTTGGTC TGACTTGTGG AATGGTATGT CCAACCTCTG ATCTTTGTGT AGGTGGATGC
AATTTATATG CCACTGAAGA GGGACCCATT AATATTGGTG GATTGCAGCA ATTTGCTACT
GAGGTATTCA AAGCAATGAG TATCCCACAG ATCAGAAATC CTTCGCTGCC TCCCCCAGAA
AAAATGTCTG AAGCCTATTC TGCAAAGATT GCTCTTTTTG GTGCTGGGCC TGCAAGTATA
AGTTGTGCTT CCTTTTTGGC TCGATTGGGG TACTCTGACA TCACTATATT TGAAAAACAA
GAATATGTTG GTGGTTTAAG TACTTCTGAA ATTCCTCAGT TCCGGCTGCC GTATGATGTA
GTGAATTTTG AGATTGAGCT AATGAAGGAC CTTGGTGTAA AGATAATTTG CGGTAAAAGC
CTTTCAGTGA ATGAAATGAC TCTTAGCACT TTGAAAGAAA AAGGCTACAA AGCTGCTTTC
ATTGGAATAG GTTTGCCAGA ACCCAATAAA GATGCCATCT TCCAAGGCCT GACGCAGGAC
CAGGGGTTTT ATACATCCAA AGACTTTTTG CCACTTGTAG CCAAAGGCAG TAAAGCAGGA
ATGTGCGCCT GTCACTCTCC ATTGCCATCG ATACGGGGAG TCGTGATTGT ACTTGGAGCT
GGAGACACTG CCTTTGACTG TGCAACATCT GCTCTACGTT GTGGAGCTCG CCGTGTGTTC
ATCGTCTTCA GAAAAGGCTT TGTTAATATA AGAGCTGTCC CTGAGGAGAT GGAACTTGCT
AAGGAAGAAA AGTGTGAATT TCTGCCATTC CTGTCCCCAC GGAAGGTTAT AGTAAAAGGT
GGGAGAATTG TTGCTATGCA GTTTGTTCGG ACAGAGCAAG ATGAAACTGG AAAATGGAAT
GAAGATGAAG ATCAGATGGT CCATCTGAAA GCCGATGTGG TCATCAGTGC CTTTGGTTCA
GTTCTGAGTG ATCCTAAAGT AAAAGAAGCC TTGAGCCCTA TAAAATTTAA CAGATGGGGT
CTCCCAGAAG TAGATCCAGA AACTATGCAA ACTAGTGAAG CATGGGTATT TGCAGGTGGT
GATGTCGTTG GTTTGGCTAA CACTACAGTG GAATCGGTGA ATGATGGAAA GCAAGCTTCT
TGGTACATTC ACAAATACGT ACAGTCACAA TATGGAGCTT CCGTTTCTGC CAAGCCTGAA
CTACCCCTCT TTTACACTCC TATTGATCTG GTGGACATTA GTGTAGAAAT GGCCGGATTG
AAGTTTATAA ATCCTTTTGG TCTTGCTAGC GCAACTCCAG CCACCAGCAC ATCAATGATT
CGAAGAGCTT TTGAAGCTGG ATGGGGTTTT GCCCTCACCA AAACTTTCTC TCTTGATAAG
GACATTGTGA CAAATGTTTC CCCCAGAATC ATCCGGGGAA CCACCTCTGG CCCCATGTAT
GGCCCTGGAC AAAGCTCCTT TCTGAATATT GAGCTCATCA GTGAGAAAAC GGCTGCATAT
TGGTGTCAAA GTGTCACTGA ACTAAAGGCT GACTTTCCAG ACAACATTGT GATTGCTAGC
ATTATGTGCA GTTACAATAA AAATGACTGG ACGGAACTTG CCAAGAAGTC TGAGGATTCT
GGAGCAGATG CCCTGGAGTT AAATTTATCA TGTCCACATG GCATGGGAGA AAGAGGAATG
GGCCTGGCCT GTGGGCAGGA TCCAGAGCTG GTGCGGAACA TCTGCCGCTG GGTTAGGCAA
GCTGTTCAGA TTCCTTTTTT TGCCAAGCTG ACCCCAAATG TCACTGATAT TGTGAGCATC
GCAAGAGCTG CAAAGGAAGG TGGTGCCAAT GGCGTTACAG CCACCAACAC TGTCTCAGGT
CTGATGGGAT TAAAATCTGA TGGCACACCT TGGCCAGCAG TGGGGATTGC AAAGCGAACT
ACATATGGAG GAGTGTCTGG GACAGCAATC AGACCTATTG CTTTGAGAGC TGTGACCTCC
ATTGCTCGTG CTCTGCCTGG ATTTCCCATT TTGGCTACTG GTGGAATTGA CTCTGCTGAA
AGTGGTCTTC AGTTTCTCCA TAGTGGTGCT TCCGTCCTCC AGGTATGCAG TGCCATTCAG
AATCAGGATT TCACTGTGAT CGAAGACTAC TGCACTGGCC TCAAAGCCCT GCTTTATCTG
AAAAGCATTG AAGAACTACA AGACTGGGAT GGACAGAGTC CAGCTACTGT GAGTCACCAG
AAAGGGAAAC CAGTTCCACG TATAGCTGAA CTCATGGACA AGAAACTGCC AAGTTTTGGA
CCTTATCTGG AACAGCGCAA GAAAATCATA GCAGAAAACA AGATTAGACT GAAAGAACAA
AATGTAGCTT TTTCACCACT TAAGAGAAAC TGTTTTATCC CCAAAAGGCC TATTCCTACC
ATCAAGGATG TAATAGGAAA AGCACTGCAG TACCTTGGAA CATTTGGTGA ATTGAGCAAC
GTAGAGCAAG TTGTGGCTAT GATTGATGAA GAAATGTGTA TCAACTGTGG TAAATGCTAC
ATGACCTGTA ATGATTCTGG CTACCAGGCT ATACAGTTTG ATCCAGAAAC CCACCTGCCC
ACCATAACCG ACACTTGTAC AGGCTGTACT CTGTGTCTCA GTGTTTGCCC TATTGTCGAC
TGCATCAAAA TGGTTTCCAG GACAACACCT TATGAACCAA AGAGAGGCGT ACCCTTATCT
GTGAATCCGG TGTGTTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_000101.2
CDS138..3215
Misc Feature(1)37..37(+)
Misc Feature(2)294..1676(+)
Misc Feature(3)309..635(+)
Misc Feature(4)717..>851(+)
Misc Feature(5)1287..1289(+)
Misc Feature(6)1731..3158(+)
Misc Feature(7)1731..2639(+)
Misc Feature(8)1791..2612(+)
Misc Feature(9)1857..2348(+)
Misc Feature(10)1857..2348(+)
Misc Feature(11)1962..2348(+)
Misc Feature(12)2139..2147(+)
Misc Feature(13)2343..2348(+)
Misc Feature(14)2988..3128(+)
Exon (1)1..176
Gene:DPYD
Gene Synonym:
Exon (2)177..287
Gene:DPYD
Gene Synonym:
Exon (3)288..370
Gene:DPYD
Gene Synonym:
Exon (4)371..458
Gene:DPYD
Gene Synonym:
Exon (5)459..620
Gene:DPYD
Gene Synonym:
Exon (6)621..817
Gene:DPYD
Gene Synonym:
Exon (7)818..899
Gene:DPYD
Gene Synonym:
Exon (8)900..987
Gene:DPYD
Gene Synonym:
Exon (9)988..1095
Gene:DPYD
Gene Synonym:
Exon (10)1096..1265
Gene:DPYD
Gene Synonym:
Exon (11)1266..1476
Gene:DPYD
Gene Synonym:
Exon (12)1477..1661
Gene:DPYD
Gene Synonym:
Exon (13)1662..1877
Gene:DPYD
Gene Synonym:
Exon (14)1878..2042
Gene:DPYD
Gene Synonym:
Exon (15)2043..2111
Gene:DPYD
Gene Synonym:
Exon (16)2112..2195
Gene:DPYD
Gene Synonym:
Exon (17)2196..2316
Gene:DPYD
Gene Synonym:
Exon (18)2317..2436
Gene:DPYD
Gene Synonym:
Exon (19)2437..2579
Gene:DPYD
Gene Synonym:
Exon (20)2580..2759
Gene:DPYD
Gene Synonym:
Exon (21)2760..2903
Gene:DPYD
Gene Synonym:
Exon (22)2904..3044
Gene:DPYD
Gene Synonym:
Exon (23)3045..4448
Gene:DPYD
Gene Synonym:
Translation
Position Chain Variation Link
1 1 c, g dbSNP:529162686
28 28 c, t dbSNP:534300645
39 39 a, t dbSNP:571741157
46 46 a, g dbSNP:551486678
50 50 a, t dbSNP:531689464
52 52 c, t dbSNP:569146754
63 63 a, g dbSNP:550078641
89 89 a, g dbSNP:758152525
92 92 g, t dbSNP:752581618
94 94 a, c dbSNP:765165101
95 95 a, g dbSNP:754506010
96 96 c, g dbSNP:529923798
120 120 c, g dbSNP:577136443
125 125 g, t dbSNP:760379014
138 138 a, c dbSNP:772950053
140 140 a, g dbSNP:768020954
144 144 c, t dbSNP:762198241
150 150 c, t dbSNP:772097379
158 158 a, g dbSNP:774730464
160 160 a, t dbSNP:769190350
167 167 g, t dbSNP:749369964
173 173 c, g dbSNP:376273539
174 174 a, g dbSNP:769820114
182 182 a, c, t dbSNP:267598790
183 183 c, g dbSNP:150036960
184 184 c, t dbSNP:764555085
185 185 a, g dbSNP:763165014
196 196 c, g dbSNP:753217888
198 198 c, t dbSNP:72549310
199 199 a, g dbSNP:80081766
210 210 c, t dbSNP:775601164
211 211 a, c dbSNP:776662759
213 213 a, g dbSNP:766635900
216 216 a, t dbSNP:770229152
222 222 c, t dbSNP:1801265
223 223 a, g dbSNP:528768620
228 228 a, g dbSNP:768501828
232 232 c, t dbSNP:748974194
233 233 a, g dbSNP:775622568
237 237 a, g dbSNP:769847078
254 254 a, g dbSNP:745409341
264 264 a, g dbSNP:780873985
274 274 a, g dbSNP:756684474
278 278 a, g dbSNP:746681994
279 279 a, g dbSNP:777238016
287 287 c, t dbSNP:370036611
295 295 a, g dbSNP:757958938
302 302 a, g dbSNP:139126323
314 314 c, t dbSNP:779270411
323 323 c, t dbSNP:181215161
324 324 a, g dbSNP:367619008
331 331 c, g, t dbSNP:371587702
345 345 c, t dbSNP:141597515
346 346 a, g dbSNP:767818267
355 355 g, t dbSNP:762102298
357 357 c, t dbSNP:189768576
364 364 c, t dbSNP:765131182
366 366 a, g dbSNP:527580106
369 369 a, t dbSNP:776692894
390 390 a, g dbSNP:757342874
394 394 c, t dbSNP:568132506
395 395 a, g, t dbSNP:201841475
397 397 g, t dbSNP:528152707
402 402 a, t dbSNP:672601289
406 406 g, t dbSNP:672601288
411 411 c, g dbSNP:143986398
413 413 a, c dbSNP:766389732
415 415 c, g dbSNP:760553268
423 423 c, g dbSNP:773159364
424 424 a, t dbSNP:771573678
425 425 c, t dbSNP:761254577
427 427 c, t dbSNP:375990187
432 432 -, tcat dbSNP:72549309
436 436 -, tcat dbSNP:539032572
437 437 c, t dbSNP:774047246
447 447 a, g dbSNP:768288280
449 449 g, t dbSNP:749699298
450 450 a, g dbSNP:150385342
452 452 a, g dbSNP:770144122
461 461 a, c dbSNP:762430779
469 469 a, g dbSNP:762533012
479 479 g, t dbSNP:370615432
480 480 a, g dbSNP:141462178
482 482 c, g dbSNP:377169736
494 494 c, t dbSNP:777348913
496 496 a, g dbSNP:771534236
500 500 a, c dbSNP:747135235
504 504 a, g dbSNP:778022685
516 516 a, g dbSNP:758514990
523 523 g, t dbSNP:748320430
530 530 a, g dbSNP:779135187
531 531 a, t dbSNP:538336580
532 532 c, t dbSNP:750224169
547 547 c, t dbSNP:767482279
551 551 g, t dbSNP:757163217
554 554 a, g dbSNP:751448860
561 561 g, t dbSNP:763623595
568 568 c, g dbSNP:762468894
569 569 c, t dbSNP:775065182
578 578 a, g dbSNP:764939839
581 581 a, g dbSNP:56108357
584 584 c, g dbSNP:759858246
588 588 a, g dbSNP:200562975
600 600 c, t dbSNP:201443458
604 604 a, g dbSNP:536577604
611 611 c, t dbSNP:190771411
626 626 a, c dbSNP:368970772
633 633 a, g dbSNP:2297595
634 634 c, t dbSNP:763061658
635 635 a, g dbSNP:139834141
637 637 g, t dbSNP:775526810
644 644 a, g dbSNP:765252243
658 658 c, g dbSNP:374827081
661 661 c, g, t dbSNP:371792178
662 662 a, g dbSNP:6670886
668 668 g, t dbSNP:774411340
670 670 a, c dbSNP:768680499
679 679 a, c dbSNP:672601287
681 681 -, a dbSNP:754785410
681 681 a, g dbSNP:748853941
682 682 a, t dbSNP:779728902
690 690 a, g dbSNP:374531732
693 693 g, t dbSNP:755645831
694 694 a, g dbSNP:115232898
705 705 a, g dbSNP:368152149
707 707 c, t dbSNP:149843476
718 718 a, g, t dbSNP:751841116
726 726 a, c dbSNP:764635955
728 728 c, t dbSNP:758927521
729 729 c, g dbSNP:753166888
730 730 a, c dbSNP:765309287
732 732 a, g dbSNP:759479759
733 733 a, g dbSNP:776973423
734 734 c, t dbSNP:766503499
738 738 a, c dbSNP:72549308
743 743 c, t dbSNP:773991224
749 749 c, g dbSNP:768519000
756 756 a, g dbSNP:749269410
758 758 a, g, t dbSNP:769440759
760 760 a, g, t dbSNP:376073289
769 769 a, g dbSNP:72549307
776 776 c, t dbSNP:190048823
783 783 a, g dbSNP:778141885
790 790 a, g dbSNP:758699471
793 793 a, g dbSNP:781184141
798 798 g, t dbSNP:146170505
807 807 g, t dbSNP:755155824
809 809 c, t dbSNP:753828034
840 840 c, t dbSNP:1801266
841 841 a, g dbSNP:755416212
842 842 a, g dbSNP:754317478
846 846 c, t dbSNP:267598789
847 847 c, t dbSNP:780025995
848 848 a, g dbSNP:139863300
852 852 a, g dbSNP:750687600
870 870 a, g dbSNP:767836989
876 876 a, c, t dbSNP:376128878
891 891 g, t dbSNP:765034707
893 893 c, t dbSNP:6675198
905 905 g, t dbSNP:556933127
907 907 a, g dbSNP:764945792
908 908 c, t dbSNP:754745863
909 909 a, g dbSNP:141726921
912 912 a, g dbSNP:45589337
915 915 a, g dbSNP:760222167
917 917 c, t dbSNP:772684506
932 932 a, g dbSNP:766962931
939 939 c, g dbSNP:761479700
940 940 a, t dbSNP:773983635
943 943 a, g dbSNP:768915005
944 944 c, t dbSNP:200702346
946 946 c, g dbSNP:775926386
953 953 a, g dbSNP:770391936
959 959 -, a dbSNP:749881640
977 977 c, t dbSNP:557212505
978 978 a, t dbSNP:746329786
979 979 c, t dbSNP:369103276
980 980 c, t dbSNP:781454573
988 988 a, g, t dbSNP:777220476
991 991 c, t dbSNP:771194906
993 993 c, t dbSNP:751113340
1005 1005 a, g dbSNP:146356975
1006 1006 a, g dbSNP:672601285
1007 1007 a, t dbSNP:777902288
1009 1009 a, g dbSNP:772320654
1012 1012 c, t dbSNP:748266854
1013 1013 c, t dbSNP:187484874
1014 1014 a, c dbSNP:779925747
1020 1020 -, c dbSNP:772507658
1024 1024 a, g dbSNP:672601284
1030 1030 a, c, t dbSNP:143879757
1031 1031 a, g dbSNP:61758443
1040 1040 a, g, t dbSNP:751049055
1047 1047 c, t dbSNP:183105782
1059 1059 -, g dbSNP:759965732
1064 1064 c, t dbSNP:762699533
1066 1066 c, t dbSNP:150437414
1071 1071 c, t dbSNP:145112791
1075 1075 c, t dbSNP:759967863
1084 1084 g, t dbSNP:749157068
1087 1087 a, g dbSNP:777347164
1092 1092 a, g dbSNP:771536388
1103 1103 c, t dbSNP:768834079
1104 1104 a, g dbSNP:201018345
1112 1112 c, t dbSNP:141376128
1113 1113 c, t dbSNP:770566506
1114 1114 c, t dbSNP:575763449
1116 1116 c, t dbSNP:369575517
1126 1126 c, t dbSNP:777560627
1131 1131 c, t dbSNP:757994597
1132 1132 a, g dbSNP:747633945
1135 1135 c, g dbSNP:778760295
1139 1139 a, c, t dbSNP:753504491
1140 1140 a, g, t dbSNP:72549306
1144 1144 c, t dbSNP:756372042
1145 1145 a, t dbSNP:750994754
1148 1148 a, t dbSNP:767903251
1151 1151 g, t dbSNP:761991197
1157 1157 g, t dbSNP:774390439
1158 1158 a, g dbSNP:764111543
1161 1161 a, g dbSNP:183385770
1162 1162 a, g dbSNP:769709846
1166 1166 c, t dbSNP:770818300
1172 1172 c, t dbSNP:1042478
1177 1177 a, g dbSNP:746777181
1181 1181 a, g dbSNP:773243157
1185 1185 c, t dbSNP:771885007
1191 1191 -, c dbSNP:771024192
1191 1191 c, g dbSNP:190577302
1194 1194 c, t dbSNP:143154602
1195 1195 a, g dbSNP:778601245
1204 1204 c, t dbSNP:754467630
1206 1206 c, t dbSNP:748958293
1207 1207 a, g dbSNP:377143350
1209 1209 c, t dbSNP:779557503
1210 1210 a, g dbSNP:573299212
1211 1211 a, t dbSNP:1042479
1213 1213 a, t dbSNP:750721736
1217 1217 c, g dbSNP:745704371
1218 1218 a, g dbSNP:768117152
1220 1220 c, t dbSNP:372369973
1221 1221 a, g dbSNP:752020412
1226 1226 c, t dbSNP:764173823
1229 1229 a, c dbSNP:763008163
1234 1234 g, t dbSNP:752985272
1245 1245 a, g dbSNP:72549305
1246 1246 -, ta dbSNP:749571474
1246 1246 c, t dbSNP:760570391
1254 1254 a, g dbSNP:772906420
1257 1257 c, t dbSNP:201785202
1262 1262 a, g dbSNP:761850800
1266 1266 a, g dbSNP:144935781
1269 1269 c, g dbSNP:201648613
1271 1271 a, g dbSNP:1126741
1277 1277 c, t dbSNP:150759598
1292 1292 -, tg dbSNP:769925158
1293 1293 -, catcac dbSNP:777662767
1293 1293 g, t dbSNP:78060119
1294 1294 -, c dbSNP:748023289
1294 1294 a, t dbSNP:576409484
1304 1304 a, g dbSNP:753482702
1306 1306 c, t dbSNP:754028972
1307 1307 a, c dbSNP:767437717
1317 1317 a, c, t dbSNP:140602333
1318 1318 g, t dbSNP:143815742
1326 1326 a, g dbSNP:762598766
1341 1341 -, a dbSNP:781098341
1346 1346 c, t dbSNP:267598788
1348 1348 g, t dbSNP:774883578
1350 1350 a, g dbSNP:769306962
1351 1351 c, t dbSNP:745512069
1353 1353 a, g dbSNP:780885126
1355 1355 a, g dbSNP:61622928
1365 1365 a, c, t dbSNP:528430685
1366 1366 a, g dbSNP:199646142
1373 1373 a, g dbSNP:56038477
1378 1378 a, g dbSNP:778867644
1380 1380 g, t dbSNP:755031341
1391 1391 a, g dbSNP:141370079
1397 1397 a, t dbSNP:200064537
1401 1401 c, g dbSNP:766700777
1402 1402 a, g dbSNP:757155354
1408 1408 a, t dbSNP:751374989
1409 1409 a, c, t dbSNP:532341730
1414 1414 c, t dbSNP:751340819
1415 1415 a, g, t dbSNP:764666241
1416 1416 g, t dbSNP:759082282
1417 1417 c, t dbSNP:200693895
1430 1430 c, t dbSNP:770549765
1431 1431 a, g dbSNP:142512579
1433 1433 c, t dbSNP:773600085
1434 1434 c, g dbSNP:772358811
1437 1437 c, g dbSNP:748620513
1438 1438 c, t dbSNP:779465366
1438 1438 -, t dbSNP:754978663
1444 1444 a, c, g dbSNP:370569731
1445 1445 a, t dbSNP:749354734
1448 1448 c, t dbSNP:780469489
1451 1451 g, t dbSNP:186169810
1463 1463 a, g dbSNP:750632457
1471 1471 c, g dbSNP:763984510
1472 1472 g, t dbSNP:758154006
1474 1474 a, c dbSNP:200709381
1481 1481 a, g dbSNP:752516372
1486 1486 c, g, t dbSNP:72975710
1494 1494 c, t dbSNP:753710779
1495 1495 a, c, g dbSNP:144395748
1506 1506 a, g dbSNP:750147471
1508 1508 c, t dbSNP:57918000
1516 1516 -, g dbSNP:779948148
1528 1528 c, t dbSNP:370707404
1529 1529 a, g dbSNP:373724295
1533 1533 c, t dbSNP:774799003
1540 1540 a, c dbSNP:199549923
1543 1543 c, t dbSNP:763557204
1552 1552 a, g dbSNP:776082092
1553 1553 c, t dbSNP:770056548
1575 1575 a, g dbSNP:745911874
1583 1583 c, t dbSNP:376470184
1584 1584 a, g dbSNP:141439344
1592 1592 a, g dbSNP:560012397
1593 1593 a, g dbSNP:747161261
1602 1602 a, g dbSNP:778776264
1612 1612 c, t dbSNP:72549304
1613 1613 a, g dbSNP:753835178
1618 1618 a, g dbSNP:779967271
1621 1621 a, g dbSNP:111858276
1631 1631 a, g, t dbSNP:116364703
1635 1635 g, t dbSNP:766885021
1642 1642 a, g dbSNP:761555670
1644 1644 a, g dbSNP:751104498
1655 1655 c, t dbSNP:201166313
1656 1656 a, g dbSNP:138391898
1658 1658 a, t dbSNP:373838132
1661 1661 a, g dbSNP:775930761
1675 1675 c, t dbSNP:760663364
1676 1676 c, t dbSNP:773519625
1678 1678 c, t dbSNP:772264512
1679 1679 c, t dbSNP:748323941
1680 1680 a, g dbSNP:148994843
1684 1684 a, c dbSNP:769514867
1689 1689 a, g dbSNP:745833535
1691 1691 a, g dbSNP:369465750
1692 1692 c, t dbSNP:672601282
1697 1697 a, g dbSNP:138979515
1709 1709 g, t dbSNP:777368221
1710 1710 c, t dbSNP:758154803
1712 1712 c, t dbSNP:752329473
1714 1714 c, g dbSNP:190951787
1724 1724 c, t dbSNP:140125782
1738 1738 a, g dbSNP:1801158
1745 1745 a, c dbSNP:766761199
1751 1751 c, t dbSNP:760853559
1752 1752 a, c, g dbSNP:142619737
1754 1754 a, g dbSNP:762029458
1755 1755 a, t dbSNP:774500505
1764 1764 a, g dbSNP:1801159
1772 1772 c, t dbSNP:759247778
1782 1782 c, g dbSNP:140039091
1787 1787 c, t dbSNP:149101842
1788 1788 a, g, t dbSNP:777425216
1791 1791 a, g dbSNP:771648776
1795 1795 c, t dbSNP:747858350
1799 1799 c, t dbSNP:778701084
1803 1803 a, c dbSNP:755407188
1807 1807 c, t dbSNP:754125729
1808 1808 a, g dbSNP:780421257
1812 1812 a, g dbSNP:756613407
1816 1816 a, g, t dbSNP:55886062
1819 1819 a, g, t dbSNP:201615754
1821 1821 a, c dbSNP:761869860
1823 1823 a, t dbSNP:751848058
1825 1825 c, t dbSNP:764270260
1829 1829 a, t dbSNP:759424419
1834 1834 c, g dbSNP:776321529
1838 1838 a, g, t dbSNP:148372305
1855 1855 c, t dbSNP:558354142
1862 1862 c, t dbSNP:538115714
1863 1863 g, t dbSNP:747627716
1864 1864 -, t dbSNP:764584080
1870 1870 c, t dbSNP:778754188
1880 1880 c, t dbSNP:555178721
1894 1894 c, t dbSNP:374527058
1907 1907 -, tc dbSNP:768130933
1911 1911 c, t dbSNP:59086055
1912 1912 a, g dbSNP:138616379
1914 1914 a, g dbSNP:145773863
1915 1915 a, g dbSNP:758489611
1918 1918 a, c dbSNP:759249769
1920 1920 a, g dbSNP:765465250
1924 1924 c, g dbSNP:756020314
1933 1933 c, t dbSNP:147601618
1934 1934 c, g dbSNP:767376585
1945 1945 a, g dbSNP:371258350
1955 1955 c, g dbSNP:774290851
1963 1963 a, c dbSNP:763572567
1969 1969 a, t dbSNP:762523739
1973 1973 a, c dbSNP:151216654
1974 1974 a, c, g dbSNP:769466648
1983 1983 a, c dbSNP:368146607
1986 1986 a, g dbSNP:776984091
1987 1987 c, t dbSNP:753707032
1988 1988 a, g dbSNP:747571447
1994 1994 a, g dbSNP:778338661
1996 1996 a, g, t dbSNP:748235192
2002 2002 a, g dbSNP:201433243
2033 2033 c, t dbSNP:17376848
2035 2035 -, c dbSNP:72549303
2038 2038 a, g dbSNP:200296941
2042 2042 c, g, t dbSNP:3918289
2043 2043 a, c dbSNP:55971861
2057 2057 c, t dbSNP:758391723
2065 2065 g, t dbSNP:752518145
2068 2068 a, g dbSNP:548783838
2074 2074 a, g dbSNP:780120302
2087 2087 c, g dbSNP:753527420
2089 2089 c, t dbSNP:765990958
2090 2090 a, g dbSNP:267598787
2100 2100 a, g dbSNP:529019871
2101 2101 a, g dbSNP:773652644
2127 2127 g, t dbSNP:138545885
2128 2128 c, t dbSNP:749982106
2139 2139 a, c dbSNP:767986711
2144 2144 a, t dbSNP:762083671
2152 2152 c, g dbSNP:763784786
2158 2158 a, g dbSNP:137999090
2160 2160 a, g dbSNP:763506271
2164 2164 a, g dbSNP:575853463
2169 2169 a, g dbSNP:769696395
2173 2173 a, g dbSNP:746115989
2176 2176 c, t dbSNP:187713395
2180 2180 -, cctggcctgtgggcag dbSNP:773499329
2186 2186 c, g dbSNP:183475941
2188 2188 g, t dbSNP:747872037
2197 2197 a, c dbSNP:755692084
2208 2208 g, t dbSNP:202212118
2211 2211 c, t dbSNP:538703919
2212 2212 a, g dbSNP:375436137
2217 2217 a, g dbSNP:756890859
2223 2223 c, t dbSNP:751190912
2224 2224 a, g dbSNP:778298325
2228 2228 a, c, g dbSNP:753296078
2234 2234 g, t dbSNP:765640386
2238 2238 a, g dbSNP:760038956
2249 2249 -, t dbSNP:770063428
2252 2252 a, t dbSNP:753891721
2254 2254 g, t dbSNP:766411970
2270 2270 a, c dbSNP:768101874
2274 2274 a, g dbSNP:773407491
2276 2276 a, t dbSNP:768507975
2278 2278 c, t dbSNP:569661196
2282 2282 c, t dbSNP:775551741
2294 2294 c, t dbSNP:769645315
2297 2297 a, c, t dbSNP:780572158
2298 2298 a, g dbSNP:145548112
2323 2323 c, t dbSNP:146529561
2330 2330 c, t dbSNP:139543981
2331 2331 a, g dbSNP:1801160
2332 2332 g, t dbSNP:60511679
2347 2347 c, t dbSNP:570122671
2349 2349 c, g dbSNP:368327291
2358 2358 c, g dbSNP:767547827
2366 2366 a, g dbSNP:757475393
2393 2393 a, g dbSNP:751746604
2401 2401 a, g dbSNP:765001324
2412 2412 c, t dbSNP:759372918
2413 2413 a, g dbSNP:267598786
2416 2416 c, g, t dbSNP:112766203
2420 2420 a, g dbSNP:772853110
2425 2425 a, g dbSNP:771646887
2437 2437 g, t dbSNP:568367673
2438 2438 g, t dbSNP:672601277
2440 2440 a, c dbSNP:56005131
2442 2442 a, g dbSNP:767468952
2445 2445 a, g dbSNP:767200577
2452 2452 c, t dbSNP:761351410
2461 2461 g, t dbSNP:200643089
2466 2466 g, t dbSNP:672601276
2467 2467 a, c, g dbSNP:374825099
2468 2468 c, t dbSNP:770087651
2471 2471 a, g dbSNP:746432900
2473 2473 a, c dbSNP:199634007
2474 2474 c, t dbSNP:372413776
2484 2484 c, t dbSNP:770958862
2485 2485 c, g dbSNP:747132274
2494 2494 c, g dbSNP:777673186
2496 2496 a, g dbSNP:758649719
2502 2502 c, t dbSNP:267598785
2508 2508 c, t dbSNP:752909847
2514 2514 a, g dbSNP:780047918
2515 2515 c, t dbSNP:547099198
2520 2520 a, g dbSNP:147800606
2529 2529 g, t dbSNP:750423752
2542 2542 g, t dbSNP:767464878
2548 2548 a, c dbSNP:761609256
2555 2555 c, t dbSNP:144271454
2558 2558 c, t dbSNP:55725052
2560 2560 a, g dbSNP:763449831
2564 2564 c, t dbSNP:762611418
2570 2570 c, t dbSNP:775111222
2571 2571 a, g dbSNP:371313778
2580 2580 a, g dbSNP:780813130
2587 2587 a, g dbSNP:757227327
2590 2590 a, c dbSNP:751399062
2591 2591 a, c dbSNP:763718987
2593 2593 g, t dbSNP:762446803
2604 2604 a, g dbSNP:752388408
2615 2615 a, c, g dbSNP:201575324
2618 2618 c, t dbSNP:759147254
2619 2619 a, c, g dbSNP:200687447
2622 2622 a, g dbSNP:199777072
2626 2626 a, g dbSNP:761302217
2629 2629 g, t dbSNP:773584401
2639 2639 c, t dbSNP:772229101
2647 2647 a, t dbSNP:748214188
2648 2648 g, t dbSNP:763174477
2664 2664 a, g dbSNP:372058915
2665 2665 c, t dbSNP:571114616
2669 2669 a, c, g dbSNP:672601275
2685 2685 a, g dbSNP:756992995
2686 2686 a, g dbSNP:765075551
2687 2687 c, t dbSNP:777542103
2700 2700 a, g dbSNP:757954074
2704 2704 c, t dbSNP:752228747
2705 2705 c, t dbSNP:534791840
2716 2716 -, a dbSNP:746991079
2719 2719 a, g dbSNP:60139309
2721 2721 c, g dbSNP:753419296
2727 2727 c, g dbSNP:766833304
2730 2730 a, g, t dbSNP:773815814
2733 2733 c, g dbSNP:768157853
2735 2735 a, g dbSNP:672601274
2736 2736 c, t dbSNP:557220418
2737 2737 a, g dbSNP:774579695
2741 2741 a, g dbSNP:372909322
2747 2747 a, t dbSNP:749586100
2756 2756 c, g dbSNP:775570841
2757 2757 a, g dbSNP:368519011
2760 2760 a, c dbSNP:201035051
2769 2769 a, t dbSNP:762911226
2776 2776 g, t dbSNP:55674432
2779 2779 c, t dbSNP:769932607
2782 2782 a, g dbSNP:759766897
2783 2783 c, t dbSNP:773002572
2790 2790 c, t dbSNP:771839581
2793 2793 c, t dbSNP:147545709
2794 2794 a, g dbSNP:1801267
2796 2796 a, c dbSNP:768200107
2798 2798 a, g, t dbSNP:559427764
2801 2801 a, t dbSNP:779573574
2805 2805 a, g dbSNP:755729055
2810 2810 a, g dbSNP:376391343
2815 2815 a, g dbSNP:188052243
2844 2844 a, g dbSNP:757695236
2852 2852 a, c dbSNP:752151811
2868 2868 g, t dbSNP:764679468
2883 2883 -, a dbSNP:778614771
2890 2890 c, t dbSNP:772826416
2899 2899 a, c, t dbSNP:771930534
2910 2910 a, g dbSNP:774134971
2912 2912 a, g dbSNP:763893877
2919 2919 a, g dbSNP:762858106
2920 2920 c, t dbSNP:775494607
2921 2921 a, g dbSNP:769227856
2926 2926 a, g dbSNP:568169006
2939 2939 a, t dbSNP:377152743
2943 2943 g, t dbSNP:137878450
2946 2946 a, g dbSNP:776236081
2949 2949 c, t dbSNP:770741452
2957 2957 c, t dbSNP:746595648
2958 2958 a, g dbSNP:778054451
2959 2959 c, g, t dbSNP:748639205
2966 2966 a, g dbSNP:779448929
2967 2967 c, g dbSNP:755428442
2974 2974 c, t dbSNP:753950237
2980 2980 a, t dbSNP:372307932
2983 2983 a, t dbSNP:67376798
2984 2984 c, t dbSNP:559276319
2985 2985 a, g dbSNP:763862486
3001 3001 -, a dbSNP:757037190
3001 3001 a, g dbSNP:762779297
3009 3009 a, g dbSNP:141044036
3022 3022 c, t dbSNP:765247038
3023 3023 c, t dbSNP:368617815
3025 3025 a, g dbSNP:776289153
3052 3052 a, g dbSNP:145529148
3057 3057 g, t dbSNP:757376267
3058 3058 a, t dbSNP:72547602
3068 3068 c, g dbSNP:376502495
3070 3070 a, g dbSNP:72547601
3071 3071 a, c dbSNP:201268750
3078 3078 a, c dbSNP:759562628
3081 3081 a, g dbSNP:753820482
3085 3085 c, t dbSNP:61757362
3087 3087 a, g dbSNP:760235888
3091 3091 a, c dbSNP:772544099
3114 3114 c, t dbSNP:202144771
3115 3115 g, t dbSNP:139459586
3116 3116 a, c, t dbSNP:768993607
3118 3118 c, g dbSNP:140989814
3120 3120 g, t dbSNP:1801268
3124 3124 a, g, t dbSNP:672601273
3129 3129 a, g, t dbSNP:745982505
3134 3134 c, g, t dbSNP:757509506
3135 3135 a, g dbSNP:151074666
3138 3138 g, t dbSNP:778911905
3147 3147 a, g dbSNP:754786483
3161 3161 a, c dbSNP:753873495
3162 3162 a, g dbSNP:766438205
3165 3165 c, t dbSNP:760485592
3167 3167 a, t dbSNP:749954216
3170 3170 c, t dbSNP:766878892
3171 3171 g, t dbSNP:761584058
3184 3184 a, g dbSNP:773868825
3185 3185 c, t dbSNP:545959800
3186 3186 a, g dbSNP:140114515
3198 3198 c, g dbSNP:148799944
3199 3199 c, t dbSNP:770320798
3200 3200 c, g dbSNP:746298645
3201 3201 a, g dbSNP:781348608
3204 3204 a, c, g, t dbSNP:114096998
3205 3205 c, t dbSNP:758640823
3206 3206 a, g dbSNP:749122978
3212 3212 g, t dbSNP:565115351
3222 3222 c, t dbSNP:779927189
3229 3229 a, g dbSNP:374367724
3231 3231 -, a dbSNP:753363470
3235 3235 g, t dbSNP:750312649
3247 3247 -, c dbSNP:763742591
3248 3248 a, c dbSNP:767121228
3267 3267 a, g dbSNP:370005502
3320 3320 c, t dbSNP:184161277
3322 3322 c, t dbSNP:150499371
3338 3338 -, a dbSNP:760411849
3367 3367 a, g dbSNP:747228600
3374 3374 a, g dbSNP:55938520
3378 3378 c, g dbSNP:534213499
3388 3388 c, t dbSNP:672601272
3489 3489 c, t dbSNP:56160474
3523 3523 a, g dbSNP:111295312
3543 3543 c, t dbSNP:192715981
3602 3602 a, g dbSNP:538293673
3637 3637 a, g dbSNP:569248743
3647 3647 a, t dbSNP:188501488
3650 3650 a, t dbSNP:1042480
3677 3677 c, g dbSNP:765158346
3679 3679 c, t dbSNP:754970493
3681 3681 a, c dbSNP:2635723
3691 3691 a, g dbSNP:753289746
3705 3705 -, aa dbSNP:367554694
3735 3735 c, t dbSNP:529449773
3765 3765 c, t dbSNP:567178473
3770 3770 -, c dbSNP:34856860
3771 3771 c, t dbSNP:765882514
3775 3775 a, g dbSNP:1042481
3782 3782 -, t dbSNP:528999329
3788 3788 a, g dbSNP:1042482
3802 3802 a, g dbSNP:772715720
3827 3827 a, g dbSNP:75542363
3850 3850 a, t dbSNP:535104911
3951 3951 a, t dbSNP:672601271
3983 3983 actgtgcacatat, gctgtgcacatac dbSNP:386633699
3983 3983 a, g dbSNP:291592
3995 3995 c, t dbSNP:291593
3998 3998 g, t dbSNP:137984871
4036 4036 c, t dbSNP:755469970
4115 4115 c, t dbSNP:17470762
4123 4123 g, t dbSNP:55696854
4126 4126 a, g dbSNP:672601270
4161 4161 a, g dbSNP:780504182
4176 4176 a, g dbSNP:672601269
4261 4261 a, c dbSNP:55992536
4277 4277 a, g dbSNP:41285690
4309 4309 a, g dbSNP:55921233
4340 4340 a, g dbSNP:553255417
4383 4383 c, t dbSNP:113520437
4404 4404 a, g dbSNP:570164196
4420 4420 a, t dbSNP:578078463

Target ORF information:

RefSeq Version NM_000110
Organism Homo sapiens (human)
Definition Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000110

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
ATGGCCCCTG TGCTCAGTAA GGACTCGGCG GACATCGAGA GTATCCTGGC TTTAAATCCT 
CGAACACAAA CTCATGCAAC TCTGTGTTCC ACTTCGGCCA AGAAATTAGA CAAGAAACAT
TGGAAAAGAA ATCCTGATAA GAACTGCTTT AATTGTGAGA AGCTGGAGAA TAATTTTGAT
GACATCAAGC ACACGACTCT TGGTGAGCGA GGAGCTCTCC GAGAAGCAAT GAGATGCCTG
AAATGTGCAG ATGCCCCGTG TCAGAAGAGC TGTCCAACTA ATCTTGATAT TAAATCATTC
ATCACAAGTA TTGCAAACAA GAACTATTAT GGAGCTGCTA AGATGATATT TTCTGACAAC
CCACTTGGTC TGACTTGTGG AATGGTATGT CCAACCTCTG ATCTTTGTGT AGGTGGATGC
AATTTATATG CCACTGAAGA GGGACCCATT AATATTGGTG GATTGCAGCA ATTTGCTACT
GAGGTATTCA AAGCAATGAG TATCCCACAG ATCAGAAATC CTTCGCTGCC TCCCCCAGAA
AAAATGTCTG AAGCCTATTC TGCAAAGATT GCTCTTTTTG GTGCTGGGCC TGCAAGTATA
AGTTGTGCTT CCTTTTTGGC TCGATTGGGG TACTCTGACA TCACTATATT TGAAAAACAA
GAATATGTTG GTGGTTTAAG TACTTCTGAA ATTCCTCAGT TCCGGCTGCC GTATGATGTA
GTGAATTTTG AGATTGAGCT AATGAAGGAC CTTGGTGTAA AGATAATTTG CGGTAAAAGC
CTTTCAGTGA ATGAAATGAC TCTTAGCACT TTGAAAGAAA AAGGCTACAA AGCTGCTTTC
ATTGGAATAG GTTTGCCAGA ACCCAATAAA GATGCCATCT TCCAAGGCCT GACGCAGGAC
CAGGGGTTTT ATACATCCAA AGACTTTTTG CCACTTGTAG CCAAAGGCAG TAAAGCAGGA
ATGTGCGCCT GTCACTCTCC ATTGCCATCG ATACGGGGAG TCGTGATTGT ACTTGGAGCT
GGAGACACTG CCTTTGACTG TGCAACATCT GCTCTACGTT GTGGAGCTCG CCGTGTGTTC
ATCGTCTTCA GAAAAGGCTT TGTTAATATA AGAGCTGTCC CTGAGGAGAT GGAACTTGCT
AAGGAAGAAA AGTGTGAATT TCTGCCATTC CTGTCCCCAC GGAAGGTTAT AGTAAAAGGT
GGGAGAATTG TTGCTATGCA GTTTGTTCGG ACAGAGCAAG ATGAAACTGG AAAATGGAAT
GAAGATGAAG ATCAGATGGT CCATCTGAAA GCCGATGTGG TCATCAGTGC CTTTGGTTCA
GTTCTGAGTG ATCCTAAAGT AAAAGAAGCC TTGAGCCCTA TAAAATTTAA CAGATGGGGT
CTCCCAGAAG TAGATCCAGA AACTATGCAA ACTAGTGAAG CATGGGTATT TGCAGGTGGT
GATGTCGTTG GTTTGGCTAA CACTACAGTG GAATCGGTGA ATGATGGAAA GCAAGCTTCT
TGGTACATTC ACAAATACGT ACAGTCACAA TATGGAGCTT CCGTTTCTGC CAAGCCTGAA
CTACCCCTCT TTTACACTCC TATTGATCTG GTGGACATTA GTGTAGAAAT GGCCGGATTG
AAGTTTATAA ATCCTTTTGG TCTTGCTAGC GCAACTCCAG CCACCAGCAC ATCAATGATT
CGAAGAGCTT TTGAAGCTGG ATGGGGTTTT GCCCTCACCA AAACTTTCTC TCTTGATAAG
GACATTGTGA CAAATGTTTC CCCCAGAATC ATCCGGGGAA CCACCTCTGG CCCCATGTAT
GGCCCTGGAC AAAGCTCCTT TCTGAATATT GAGCTCATCA GTGAGAAAAC GGCTGCATAT
TGGTGTCAAA GTGTCACTGA ACTAAAGGCT GACTTTCCAG ACAACATTGT GATTGCTAGC
ATTATGTGCA GTTACAATAA AAATGACTGG ACGGAACTTG CCAAGAAGTC TGAGGATTCT
GGAGCAGATG CCCTGGAGTT AAATTTATCA TGTCCACATG GCATGGGAGA AAGAGGAATG
GGCCTGGCCT GTGGGCAGGA TCCAGAGCTG GTGCGGAACA TCTGCCGCTG GGTTAGGCAA
GCTGTTCAGA TTCCTTTTTT TGCCAAGCTG ACCCCAAATG TCACTGATAT TGTGAGCATC
GCAAGAGCTG CAAAGGAAGG TGGTGCCAAT GGCGTTACAG CCACCAACAC TGTCTCAGGT
CTGATGGGAT TAAAATCTGA TGGCACACCT TGGCCAGCAG TGGGGATTGC AAAGCGAACT
ACATATGGAG GAGTGTCTGG GACAGCAATC AGACCTATTG CTTTGAGAGC TGTGACCTCC
ATTGCTCGTG CTCTGCCTGG ATTTCCCATT TTGGCTACTG GTGGAATTGA CTCTGCTGAA
AGTGGTCTTC AGTTTCTCCA TAGTGGTGCT TCCGTCCTCC AGGTATGCAG TGCCATTCAG
AATCAGGATT TCACTGTGAT CGAAGACTAC TGCACTGGCC TCAAAGCCCT GCTTTATCTG
AAAAGCATTG AAGAACTACA AGACTGGGAT GGACAGAGTC CAGCTACTGT GAGTCACCAG
AAAGGGAAAC CAGTTCCACG TATAGCTGAA CTCATGGACA AGAAACTGCC AAGTTTTGGA
CCTTATCTGG AACAGCGCAA GAAAATCATA GCAGAAAACA AGATTAGACT GAAAGAACAA
AATGTAGCTT TTTCACCACT TAAGAGAAAC TGTTTTATCC CCAAAAGGCC TATTCCTACC
ATCAAGGATG TAATAGGAAA AGCACTGCAG TACCTTGGAA CATTTGGTGA ATTGAGCAAC
GTAGAGCAAG TTGTGGCTAT GATTGATGAA GAAATGTGTA TCAACTGTGG TAAATGCTAC
ATGACCTGTA ATGATTCTGG CTACCAGGCT ATACAGTTTG ATCCAGAAAC CCACCTGCCC
ACCATAACCG ACACTTGTAC AGGCTGTACT CTGTGTCTCA GTGTTTGCCC TATTGTCGAC
TGCATCAAAA TGGTTTCCAG GACAACACCT TATGAACCAA AGAGAGGCGT ACCCTTATCT
GTGAATCCGG TGTGTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21185
Accession Version NM_001160301.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 522bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product dihydropyrimidine dehydrogenase [NADP(+)] isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA721123.1, BC008379.1 and AC138135.2. This sequence is a reference standard in the RefSeqGene project. Summary: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]. Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC064027.1, BC108742.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
ATGGCCCCTG TGCTCAGTAA GGACTCGGCG GACATCGAGA GTATCCTGGC TTTAAATCCT 
CGAACACAAA CTCATGCAAC TCTGTGTTCC ACTTCGGCCA AGAAATTAGA CAAGAAACAT
TGGAAAAGAA ATCCTGATAA GAACTGCTTT AATTGTGAGA AGCTGGAGAA TAATTTTGAT
GACATCAAGC ACACGACTCT TGGTGAGCGA GGAGCTCTCC GAGAAGCAAT GAGATGCCTG
AAATGTGCAG ATGCCCCGTG TCAGAAGAGC TGTCCAACTA ATCTTGATAT TAAATCATTC
ATCACAAGTA TTGCAAACAA GAACTATTAT GGAGCTGCTA AGATGATATT TTCTGACAAC
CCACTTGGTC TGACTTGTGG AATGGTATGT CCAACCTCTG ATCTTTGTGT AGGTGGATGC
AATTTATATG CCACTGAAGA GGGACCCATT AATATTGGTG GATTGCAGCA ATTTGCTACT
GAGACTTTGA TCCTGGCTTT CTCTTTAATG AATCATTTGT AA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001153773.1
CDS138..659
Misc Feature(1)309..623(+)
Exon (1)1..176
Gene:DPYD
Gene Synonym:
Exon (2)177..287
Gene:DPYD
Gene Synonym:
Exon (3)288..370
Gene:DPYD
Gene Synonym:
Exon (4)371..458
Gene:DPYD
Gene Synonym:
Exon (5)459..620
Gene:DPYD
Gene Synonym:
Exon (6)621..1789
Gene:DPYD
Gene Synonym:
Translation
Position Chain Variation Link
1 1 c, g dbSNP:529162686
28 28 c, t dbSNP:534300645
39 39 a, t dbSNP:571741157
46 46 a, g dbSNP:551486678
50 50 a, t dbSNP:531689464
52 52 c, t dbSNP:569146754
63 63 a, g dbSNP:550078641
89 89 a, g dbSNP:758152525
92 92 g, t dbSNP:752581618
94 94 a, c dbSNP:765165101
95 95 a, g dbSNP:754506010
96 96 c, g dbSNP:529923798
120 120 c, g dbSNP:577136443
125 125 g, t dbSNP:760379014
138 138 a, c dbSNP:772950053
140 140 a, g dbSNP:768020954
144 144 c, t dbSNP:762198241
150 150 c, t dbSNP:772097379
158 158 a, g dbSNP:774730464
160 160 a, t dbSNP:769190350
167 167 g, t dbSNP:749369964
173 173 c, g dbSNP:376273539
174 174 a, g dbSNP:769820114
182 182 a, c, t dbSNP:267598790
183 183 c, g dbSNP:150036960
184 184 c, t dbSNP:764555085
185 185 a, g dbSNP:763165014
196 196 c, g dbSNP:753217888
198 198 c, t dbSNP:72549310
199 199 a, g dbSNP:80081766
210 210 c, t dbSNP:775601164
211 211 a, c dbSNP:776662759
213 213 a, g dbSNP:766635900
216 216 a, t dbSNP:770229152
222 222 c, t dbSNP:1801265
223 223 a, g dbSNP:528768620
228 228 a, g dbSNP:768501828
232 232 c, t dbSNP:748974194
233 233 a, g dbSNP:775622568
237 237 a, g dbSNP:769847078
254 254 a, g dbSNP:745409341
264 264 a, g dbSNP:780873985
274 274 a, g dbSNP:756684474
278 278 a, g dbSNP:746681994
279 279 a, g dbSNP:777238016
287 287 c, t dbSNP:370036611
295 295 a, g dbSNP:757958938
302 302 a, g dbSNP:139126323
314 314 c, t dbSNP:779270411
323 323 c, t dbSNP:181215161
324 324 a, g dbSNP:367619008
331 331 c, g, t dbSNP:371587702
345 345 c, t dbSNP:141597515
346 346 a, g dbSNP:767818267
355 355 g, t