The following DRD4 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DRD4 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1260bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||D(4) dopamine receptor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from EU432112.1, AP006284.2,
L12398.1 and BM674709.1.
This sequence is a reference standard in the RefSeqGene project.
On May 13, 2010 this sequence version replaced gi:32483396.
Summary: This gene encodes the D4 subtype of the dopamine receptor.
The D4 subtype is a G-protein coupled receptor which inhibits
adenylyl cyclase. It is a target for drugs which treat
schizophrenia and Parkinson disease. Mutations in this gene have
been associated with various behavioral phenotypes, including
autonomic nervous system dysfunction, attention
deficit/hyperactivity disorder, and the personality trait of
novelty seeking. This gene contains a polymorphic number (2-10
copies) of tandem 48 nt repeats; the sequence shown contains four
repeats. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: EU432112.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.