The following APLNR gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APLNR gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1143bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AL553350.3, BX439288.2,
AK075252.1, AK315542.1, AP001786.4 and BC032688.1.
On Jul 9, 2009 this sequence version replaced gi:86604722.
Summary: This gene encodes a member of the G protein-coupled
receptor gene family. The encoded protein is related to the
angiotensin receptor, but is actually an apelin receptor that
inhibits adenylate cyclase activity and plays a counter-regulatory
role against the pressure action of angiotensin II by exerting
hypertensive effect. It functions in the cardiovascular and central
nervous systems, in glucose metabolism, in embryonic and tumor
angiogenesis and as a human immunodeficiency virus (HIV-1)
coreceptor. Two transcript variants resulting from alternative
splicing have been identified. [provided by RefSeq, Jul 2009].
Transcript Variant: This variant (1) represents the longer
transcript and encodes the functional protein.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
COMPLETENESS: complete on the 3' end.