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EFNB1 ephrin-B1 [Homo sapiens (human)]

Gene Symbol EFNB1
Entrez Gene ID 1947
Full Name ephrin-B1
Synonyms CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2
General protein information
Preferred Names
ephrin-B1
Names
ephrin-B1
EFL-3
LERK-2
ELK ligand
ligand of eph-related kinase 2
eph-related receptor tyrosine kinase ligand 2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq12

Summary The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

300035

Disorder Html: Craniofrontonasal dysplasia, 304110 (3)





The following EFNB1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EFNB1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu26381 NM_004429 Homo sapiens ephrin-B1 (EFNB1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$379

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu26381
Accession Version NM_004429.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1041bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu26381D_COA.pdf (pdf)
Update Date 07-MAY-2015
Organism Homo sapiens (human)
Product ephrin-B1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC016649.1, CB132233.1 and BM972960.1. This sequence is a reference standard in the RefSeqGene project. On Apr 18, 2008 this sequence version replaced gi:31317225. Summary: The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016649.1, BC052979.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 23335590 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCTCGGC CTGGGCAGCG TTGGCTCGGC AAGTGGCTTG TGGCGATGGT CGTGTGGGCG 
CTGTGCCGGC TCGCCACACC GCTGGCCAAG AACCTGGAGC CCGTATCCTG GAGCTCCCTC
AACCCCAAGT TCCTGAGTGG GAAGGGCTTG GTGATCTATC CGAAAATTGG AGACAAGCTG
GACATCATCT GCCCCCGAGC AGAAGCAGGG CGGCCCTATG AGTACTACAA GCTGTACCTG
GTGCGGCCTG AGCAGGCAGC TGCCTGTAGC ACAGTTCTCG ACCCCAACGT GTTGGTCACC
TGCAATAGGC CAGAGCAGGA AATACGCTTT ACCATCAAGT TCCAGGAGTT CAGCCCCAAC
TACATGGGCC TGGAGTTCAA GAAGCACCAT GATTACTACA TTACCTCAAC ATCCAATGGA
AGCCTGGAGG GGCTGGAAAA CCGGGAGGGC GGTGTGTGCC GCACACGCAC CATGAAGATC
ATCATGAAGG TTGGGCAAGA TCCCAATGCT GTGACGCCTG AGCAGCTGAC TACCAGCAGG
CCCAGCAAGG AGGCAGACAA CACTGTCAAG ATGGCCACAC AGGCCCCTGG TAGTCGGGGC
TCCCTGGGTG ACTCTGATGG CAAGCATGAG ACTGTGAACC AGGAAGAGAA GAGTGGCCCA
GGTGCAAGTG GGGGCAGCAG CGGGGACCCT GATGGCTTCT TCAACTCCAA GGTGGCATTG
TTCGCGGCTG TCGGTGCCGG TTGCGTCATC TTCCTGCTCA TCATCATCTT CCTGACGGTC
CTACTACTGA AGCTACGCAA GCGGCACCGC AAGCACACAC AGCAGCGGGC GGCTGCCCTC
TCGCTCAGTA CCCTGGCCAG TCCCAAGGGG GGCAGTGGCA CAGCGGGCAC CGAGCCCAGC
GACATCATCA TTCCCTTACG GACTACAGAG AACAACTACT GCCCCCACTA TGAGAAGGTG
AGTGGGGACT ACGGGCACCC TGTCTACATC GTCCAAGAGA TGCCGCCCCA GAGCCCGGCG
AACATCTACT ACAAGGTCTG A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_004420.1
CDS781..1821
Misc Feature(1)250..252(+)
Misc Feature(2)677..688(+)
Misc Feature(3)871..1275(+)
Misc Feature(4)955..1155(+)
Misc Feature(5)1492..1554(+)
Misc Feature(6)1525..>1761(+)
Misc Feature(7)1639..1641(+)
Misc Feature(8)1750..1752(+)
Misc Feature(9)1765..1767(+)
Misc Feature(10)1807..1809(+)
Misc Feature(11)1810..1818(+)
Exon (1)1..908
Gene:EFNB1
Gene Synonym:
Exon (2)909..1186
Gene:EFNB1
Gene Synonym:
Exon (3)1187..1279
Gene:EFNB1
Gene Synonym:
Exon (4)1280..1408
Gene:EFNB1
Gene Synonym:
Exon (5)1409..3331
Gene:EFNB1
Gene Synonym:
Translation
Position Chain Variation Link
11 11 a, g dbSNP:764486766
45 45 -, gga dbSNP:200409757
86 86 c, t dbSNP:189750013
128 128 a, g dbSNP:750244748
133 133 c, t dbSNP:567247235
167 167 c, g dbSNP:766023468
173 173 c, t dbSNP:753539365
193 193 a, c dbSNP:754472257
213 213 a, c dbSNP:534650507
254 254 c, t dbSNP:751999363
273 273 c, g dbSNP:184030244
342 342 a, g dbSNP:781366089
396 396 g, t dbSNP:187341605
502 502 c, g, t dbSNP:756470369
512 512 g, t dbSNP:780296718
552 552 a, g dbSNP:139698751
566 566 a, c dbSNP:768850247
567 567 c, t dbSNP:774575536
589 589 c, g dbSNP:748040560
601 601 a, c dbSNP:772069321
647 647 c, g dbSNP:773063048
658 658 a, g dbSNP:760496981
721 721 g, t dbSNP:766147279
734 734 g, t dbSNP:780097161
757 757 a, g dbSNP:749239215
759 759 -, a dbSNP:35579950
770 770 -, c dbSNP:778220067
774 774 c, t dbSNP:768720228
775 775 a, g dbSNP:774349071
785 785 c, t dbSNP:748401151
787 787 c, t dbSNP:772228172
788 788 c, g dbSNP:373904459
792 792 a, t dbSNP:760982643
798 798 a, g dbSNP:776263722
813 813 a, g dbSNP:777057878
820 820 g, t dbSNP:760050554
838 838 g, t dbSNP:763647626
850 850 c, t dbSNP:759194644
852 852 c, t dbSNP:764672146
865 865 g, t dbSNP:767027730
879 879 g, t dbSNP:750127847
889 889 g, t dbSNP:104894802
890 890 a, g dbSNP:104894803
913 913 c, t dbSNP:145603720
941 941 a, c, t dbSNP:104894801
942 942 a, g dbSNP:1056028
944 944 a, g dbSNP:771228253
972 972 c, t dbSNP:148907346
976 976 c, t dbSNP:104894804
977 977 a, g dbSNP:748103349
985 985 a, g dbSNP:765712163
986 986 c, t dbSNP:776085390
991 991 c, t dbSNP:367996552
992 992 a, g dbSNP:767055938
1017 1017 c, t dbSNP:750035783
1023 1023 a, g dbSNP:755885387
1025 1025 a, g dbSNP:370637906
1042 1042 a, g dbSNP:143648191
1059 1059 c, t dbSNP:754924952
1060 1060 a, g dbSNP:778669520
1074 1074 a, g dbSNP:752714814
1075 1075 a, g dbSNP:758345370
1095 1095 a, g dbSNP:777846246
1106 1106 a, g dbSNP:747219481
1112 1112 c, t dbSNP:104894796
1113 1113 c, t dbSNP:771211723
1119 1119 a, g dbSNP:781514536
1155 1155 a, g dbSNP:746168241
1171 1171 a, g dbSNP:770225645
1179 1179 c, t dbSNP:775791339
1185 1185 a, c dbSNP:763525185
1196 1196 a, g, t dbSNP:148094474
1202 1202 c, g dbSNP:142430452
1205 1205 c, t dbSNP:748061613
1209 1209 a, g dbSNP:746106034
1215 1215 a, g dbSNP:769991747
1222 1222 c, t dbSNP:780521355
1227 1227 a, g dbSNP:749751971
1230 1230 c, t dbSNP:760426873
1231 1231 a, g dbSNP:28936069
1232 1232 g, t dbSNP:28936070
1241 1241 a, g dbSNP:146636295
1252 1252 a, g dbSNP:28936071
1254 1254 g, t dbSNP:28935170
1256 1256 a, g dbSNP:772828931
1276 1276 c, t dbSNP:587777109
1289 1289 c, t dbSNP:147599832
1291 1291 a, g dbSNP:779526112
1295 1295 c, t dbSNP:7889678
1296 1296 a, g dbSNP:377269776
1306 1306 c, g dbSNP:762345929
1320 1320 a, g, t dbSNP:143162125
1324 1324 a, g dbSNP:767884649
1329 1329 g, t dbSNP:762694943
1340 1340 a, g dbSNP:763881049
1345 1345 a, g dbSNP:150883256
1346 1346 c, t dbSNP:16989105
1375 1375 c, t dbSNP:546056194
1377 1377 g, t dbSNP:200409169
1379 1379 c, g dbSNP:149648624
1388 1388 g, t dbSNP:766918704
1396 1396 c, g dbSNP:756265628
1399 1399 a, g dbSNP:754048678
1423 1423 a, g dbSNP:768426785
1425 1425 a, g dbSNP:144441935
1437 1437 c, t dbSNP:761704495
1442 1442 g, t dbSNP:772092082
1446 1446 a, g dbSNP:376706341
1455 1455 c, t dbSNP:760769932
1462 1462 a, g dbSNP:766378296
1465 1465 g, t dbSNP:139138728
1482 1482 c, t dbSNP:759896368
1484 1484 a, c dbSNP:369393911
1486 1486 g, t dbSNP:753155032
1495 1495 a, g dbSNP:758811344
1503 1503 c, g, t dbSNP:778301964
1504 1504 a, g dbSNP:755591908
1505 1505 c, t dbSNP:779487954
1506 1506 a, g dbSNP:748930955
1507 1507 a, g dbSNP:201249059
1511 1511 g, t dbSNP:768333182
1512 1512 c, g, t dbSNP:7890214
1515 1515 g, t dbSNP:771797163
1518 1518 c, t dbSNP:773137160
1524 1524 c, t dbSNP:376359844
1525 1525 a, c, g dbSNP:369662868
1539 1539 c, t dbSNP:35567709
1540 1540 a, g dbSNP:765607277
1542 1542 c, g dbSNP:752991896
1548 1548 c, t dbSNP:763308440
1554 1554 a, g, t dbSNP:373289351
1568 1568 c, t dbSNP:752091564
1569 1569 a, g dbSNP:757771029
1571 1571 a, g dbSNP:779503158
1572 1572 a, g dbSNP:753392421
1576 1576 c, t dbSNP:754504608
1582 1582 c, t dbSNP:778499542
1583 1583 a, g dbSNP:747763749
1585 1585 c, t dbSNP:771846578
1588 1588 c, t dbSNP:777491240
1596 1596 c, t dbSNP:746962380
1598 1598 c, g dbSNP:770815723
1599 1599 a, g dbSNP:776831490
1607 1607 a, g dbSNP:139877825
1608 1608 a, g, t dbSNP:183532593
1610 1610 c, t dbSNP:758554867
1611 1611 a, g dbSNP:763142613
1623 1623 a, g, t dbSNP:143341175
1648 1648 a, g dbSNP:778402835
1660 1660 a, g dbSNP:376456176
1664 1664 c, t dbSNP:369967894
1665 1665 a, g dbSNP:754420974
1671 1671 c, t dbSNP:35202024
1677 1677 c, t dbSNP:752385540
1680 1680 c, t dbSNP:758057319
1721 1721 a, g dbSNP:777593766
1724 1724 c, t dbSNP:746829979
1726 1726 c, t dbSNP:757141230
1727 1727 a, g dbSNP:781238120
1740 1740 c, g dbSNP:370977525
1752 1752 c, t dbSNP:769979924
1758 1758 a, c dbSNP:372510064
1768 1768 a, g dbSNP:749494191
1771 1771 a, g, t dbSNP:376262683
1784 1784 c, t dbSNP:370690590
1785 1785 a, g dbSNP:770643654
1794 1794 c, t dbSNP:767875215
1797 1797 a, g dbSNP:773654970
1799 1799 c, t dbSNP:761232213
1800 1800 a, g dbSNP:764727240
1804 1804 a, g dbSNP:752189120
1815 1815 a, g dbSNP:758047692
1822 1822 a, g dbSNP:763606269
1827 1827 c, t dbSNP:2230423
1828 1828 a, g dbSNP:757059116
1832 1832 c, t dbSNP:781189322
1833 1833 a, c, g dbSNP:745795283
1841 1841 a, g, t dbSNP:745471569
1846 1846 c, t dbSNP:768808444
1853 1853 c, t dbSNP:778933278
1855 1855 a, g dbSNP:769366668
1857 1857 c, t dbSNP:772415563
1858 1858 a, g dbSNP:773636810
1859 1859 a, g dbSNP:746235111
1867 1867 c, g, t dbSNP:775252862
1868 1868 a, g dbSNP:777218714
1872 1872 c, t dbSNP:762330996
1881 1881 c, t dbSNP:187874806
1913 1913 c, t dbSNP:192352004
1939 1939 g, t dbSNP:773851995
1957 1957 c, t dbSNP:556015483
1983 1983 c, t dbSNP:768292892
1989 1989 c, g dbSNP:183063780
2018 2018 c, t dbSNP:773241593
2062 2062 c, t dbSNP:777158947
2120 2120 c, g dbSNP:759983838
2125 2125 c, t dbSNP:3196658
2173 2173 c, t dbSNP:41312134
2207 2207 -, t dbSNP:201242983
2213 2213 -, t dbSNP:35418748
2273 2273 c, g dbSNP:753021343
2328 2328 a, g dbSNP:188235570
2356 2356 c, t dbSNP:572893880
2390 2390 a, g dbSNP:1804569
2429 2429 g, t dbSNP:1804568
2446 2446 c, t dbSNP:751436746
2524 2524 -, ca, caca, cccaca dbSNP:772633678
2542 2542 -, ac dbSNP:71947464
2551 2551 a, c dbSNP:199636325
2551 2551 -, c dbSNP:200158453
2552 2552 -, c, ca, cacac dbSNP:61387446
2553 2553 -, c, cac dbSNP:58007755
2553 2553 a, c dbSNP:16990748
2554 2554 -, c dbSNP:57536611
2554 2554 a, c dbSNP:59751961
2555 2555 -, c dbSNP:59133604
2555 2555 a, c dbSNP:688969
2557 2557 a, c dbSNP:779563777
2605 2605 c, g dbSNP:367956022
2660 2660 c, t dbSNP:747669043
2677 2677 a, g dbSNP:749040540
2697 2697 a, g dbSNP:768215054
2704 2704 c, g dbSNP:771518919
2708 2708 g, t dbSNP:1056069
2715 2715 a, g dbSNP:1056070
2729 2729 a, g dbSNP:774010970
2851 2851 c, t dbSNP:199742261
2858 2858 -, c dbSNP:747472229
2890 2890 c, t dbSNP:772737811
2916 2916 a, g dbSNP:760553708
2934 2934 a, g dbSNP:771597894
2954 2954 a, g dbSNP:770866635
2964 2964 a, g dbSNP:777324758
3030 3030 g, t dbSNP:192955667
3085 3085 c, t dbSNP:184659322
3118 3118 a, g dbSNP:775505331
3121 3121 a, g dbSNP:763246013
3174 3174 c, t dbSNP:375146294
3179 3179 g, t dbSNP:15090
3221 3221 a, g dbSNP:764109940
3287 3287 -, a dbSNP:751666385
3307 3307 a, c dbSNP:765483945

Target ORF information:

RefSeq Version NM_004429
Organism Homo sapiens (human)
Definition Homo sapiens ephrin-B1 (EFNB1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_004429

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCTCGGC CTGGGCAGCG TTGGCTCGGC AAGTGGCTTG TGGCGATGGT CGTGTGGGCG 
CTGTGCCGGC TCGCCACACC GCTGGCCAAG AACCTGGAGC CCGTATCCTG GAGCTCCCTC
AACCCCAAGT TCCTGAGTGG GAAGGGCTTG GTGATCTATC CGAAAATTGG AGACAAGCTG
GACATCATCT GCCCCCGAGC AGAAGCAGGG CGGCCCTATG AGTACTACAA GCTGTACCTG
GTGCGGCCTG AGCAGGCAGC TGCCTGTAGC ACAGTTCTCG ACCCCAACGT GTTGGTCACC
TGCAATAGGC CAGAGCAGGA AATACGCTTT ACCATCAAGT TCCAGGAGTT CAGCCCCAAC
TACATGGGCC TGGAGTTCAA GAAGCACCAT GATTACTACA TTACCTCAAC ATCCAATGGA
AGCCTGGAGG GGCTGGAAAA CCGGGAGGGC GGTGTGTGCC GCACACGCAC CATGAAGATC
ATCATGAAGG TTGGGCAAGA TCCCAATGCT GTGACGCCTG AGCAGCTGAC TACCAGCAGG
CCCAGCAAGG AGGCAGACAA CACTGTCAAG ATGGCCACAC AGGCCCCTGG TAGTCGGGGC
TCCCTGGGTG ACTCTGATGG CAAGCATGAG ACTGTGAACC AGGAAGAGAA GAGTGGCCCA
GGTGCAAGTG GGGGCAGCAG CGGGGACCCT GATGGCTTCT TCAACTCCAA GGTGGCATTG
TTCGCGGCTG TCGGTGCCGG TTGCGTCATC TTCCTGCTCA TCATCATCTT CCTGACGGTC
CTACTACTGA AGCTACGCAA GCGGCACCGC AAGCACACAC AGCAGCGGGC GGCTGCCCTC
TCGCTCAGTA CCCTGGCCAG TCCCAAGGGG GGCAGTGGCA CAGCGGGCAC CGAGCCCAGC
GACATCATCA TTCCCTTACG GACTACAGAG AACAACTACT GCCCCCACTA TGAGAAGGTG
AGTGGGGACT ACGGGCACCC TGTCTACATC GTCCAAGAGA TGCCGCCCCA GAGCCCGGCG
AACATCTACT ACAAGGTCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.