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ELAVL1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol ELAVL1
Entrez Gene ID 1994
Full Name ELAV like RNA binding protein 1
Synonyms ELAV1, HUR, Hua, MelG
General protein information
Preferred Names
ELAV-like protein 1
Names
ELAV-like protein 1
Hu antigen R
hu-antigen R
embryonic lethal, abnormal vision, drosophila, homolog-like 1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.2

Summary The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]. lac of sum
Disorder MIM:

603466


mRNA and Protein(s)

mRNA Protein Name
XM_011527777 XP_011526079 ELAV-like protein 1 isoform X1
NM_001419 NP_001410 ELAV-like protein 1



Homo sapiens (human) ELAVL1 NP_001410.2
Pan troglodytes (chimpanzee) ELAVL1 XP_001156587.2
Macaca mulatta (Rhesus monkey) ELAVL1 XP_001092907.2
Canis lupus familiaris (dog) ELAVL1 XP_854218.1
Bos taurus (cattle) ELAVL1 NP_001069922.1
Mus musculus (house mouse) Elavl1 NP_034615.2
Rattus norvegicus (Norway rat) Elavl1 NP_001102318.1
Gallus gallus (chicken) ELAVL1 NP_990164.1
Danio rerio (zebrafish) hug NP_570984.1
Xenopus (Silurana) tropicalis (western clawed frog) elavl1 NP_001005461.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ELAVL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ELAVL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu57461 XM_011527777 PREDICTED: Homo sapiens ELAV like RNA binding protein 1 (ELAVL1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu23723
NM_001419 Homo sapiens ELAV like RNA binding protein 1 (ELAVL1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$154.50-$216.30
$309.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu57461
Clone ID Related Accession (Same CDS sequence) XM_011527777
Accession Version XM_011527777.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1062bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product ELAV-like protein 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011295.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGGTAGTG GTGGCAGGAG TGCTCAGGTG TCCACTGGGC AGAGGGCTTG GCTGTTACCC 
TGCAGATTTT TGAAAAATAC AATGTCTAAT GGTTATGAAG ACCACATGGC CGAAGACTGC
AGGGGTGACA TCGGGAGAAC GAATTTGATC GTCAACTACC TCCCTCAGAA CATGACCCAG
GATGAGTTAC GAAGCCTGTT CAGCAGCATT GGTGAAGTTG AATCTGCAAA ACTTATTCGG
GATAAAGTAG CAGGACACAG CTTGGGCTAT GGCTTTGTGA ACTACGTGAC CGCGAAGGAT
GCAGAGAGAG CGATCAACAC GCTGAACGGC TTGAGGCTCC AGTCAAAAAC CATTAAGGTG
TCGTATGCTC GCCCGAGCTC AGAGGTGATC AAAGACGCCA ACTTGTACAT CAGCGGGCTC
CCGCGGACCA TGACCCAGAA GGACGTAGAA GACATGTTCT CTCGGTTTGG GCGGATCATC
AACTCGCGGG TCCTCGTGGA TCAGACTACA GGTTTGTCCA GAGGGGTTGC GTTTATCCGG
TTTGACAAAC GGTCGGAGGC AGAAGAGGCA ATTACCAGTT TCAATGGTCA TAAACCCCCA
GGTTCCTCTG AGCCCATCAC AGTGAAGTTT GCAGCCAACC CCAACCAGAA CAAAAACGTG
GCACTCCTCT CGCAGCTGTA CCACTCGCCA GCGCGACGGT TCGGAGGCCC CGTTCACCAC
CAGGCGCAGA GATTCAGGTT CTCCCCCATG GGCGTCGATC ACATGAGCGG GCTCTCTGGC
GTCAACGTGC CAGGAAACGC CTCCTCCGGC TGGTGCATTT TCATCTACAA CCTGGGGCAG
GATGCCGACG AGGGGATCCT CTGGCAGATG TTTGGGCCGT TTGGTGCCGT CACCAATGTG
AAAGTGATCC GCGACTTCAA CACCAACAAG TGCAAAGGGT TTGGCTTTGT GACCATGACA
AACTATGAAG AAGCCGCGAT GGCCATAGCC AGCCTGAACG GCTACCGCCT GGGGGACAAA
ATCTTACAGG TTTCCTTCAA AACCAACAAG TCCCACAAAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011526079.1
CDS88..1149
Misc Feature(1)223..1146(+)
Misc Feature(2)223..456(+)
Misc Feature(3)229..456(+)
Misc Feature(4)484..735(+)
Misc Feature(5)487..723(+)
Misc Feature(6)895..1146(+)
Translation

Target ORF information:

RefSeq Version XM_011527777
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ELAV like RNA binding protein 1 (ELAVL1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011527777

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGGTAGTG GTGGCAGGAG TGCTCAGGTG TCCACTGGGC AGAGGGCTTG GCTGTTACCC 
TGCAGATTTT TGAAAAATAC AATGTCTAAT GGTTATGAAG ACCACATGGC CGAAGACTGC
AGGGGTGACA TCGGGAGAAC GAATTTGATC GTCAACTACC TCCCTCAGAA CATGACCCAG
GATGAGTTAC GAAGCCTGTT CAGCAGCATT GGTGAAGTTG AATCTGCAAA ACTTATTCGG
GATAAAGTAG CAGGACACAG CTTGGGCTAT GGCTTTGTGA ACTACGTGAC CGCGAAGGAT
GCAGAGAGAG CGATCAACAC GCTGAACGGC TTGAGGCTCC AGTCAAAAAC CATTAAGGTG
TCGTATGCTC GCCCGAGCTC AGAGGTGATC AAAGACGCCA ACTTGTACAT CAGCGGGCTC
CCGCGGACCA TGACCCAGAA GGACGTAGAA GACATGTTCT CTCGGTTTGG GCGGATCATC
AACTCGCGGG TCCTCGTGGA TCAGACTACA GGTTTGTCCA GAGGGGTTGC GTTTATCCGG
TTTGACAAAC GGTCGGAGGC AGAAGAGGCA ATTACCAGTT TCAATGGTCA TAAACCCCCA
GGTTCCTCTG AGCCCATCAC AGTGAAGTTT GCAGCCAACC CCAACCAGAA CAAAAACGTG
GCACTCCTCT CGCAGCTGTA CCACTCGCCA GCGCGACGGT TCGGAGGCCC CGTTCACCAC
CAGGCGCAGA GATTCAGGTT CTCCCCCATG GGCGTCGATC ACATGAGCGG GCTCTCTGGC
GTCAACGTGC CAGGAAACGC CTCCTCCGGC TGGTGCATTT TCATCTACAA CCTGGGGCAG
GATGCCGACG AGGGGATCCT CTGGCAGATG TTTGGGCCGT TTGGTGCCGT CACCAATGTG
AAAGTGATCC GCGACTTCAA CACCAACAAG TGCAAAGGGT TTGGCTTTGT GACCATGACA
AACTATGAAG AAGCCGCGAT GGCCATAGCC AGCCTGAACG GCTACCGCCT GGGGGACAAA
ATCTTACAGG TTTCCTTCAA AACCAACAAG TCCCACAAAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23723
Clone ID Related Accession (Same CDS sequence) NM_001419
Accession Version NM_001419.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 981bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ELAV-like protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU542524.1, BC003376.2, W37464.1, AI375368.1, AL713686.1, AW139417.1, BM696191.1 and BM664469.1. On Nov 7, 2003 this sequence version replaced gi:4503550. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU542524.1, BC003376.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962342, SAMEA962347 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCTAATG GTTATGAAGA CCACATGGCC GAAGACTGCA GGGGTGACAT CGGGAGAACG 
AATTTGATCG TCAACTACCT CCCTCAGAAC ATGACCCAGG ATGAGTTACG AAGCCTGTTC
AGCAGCATTG GTGAAGTTGA ATCTGCAAAA CTTATTCGGG ATAAAGTAGC AGGACACAGC
TTGGGCTATG GCTTTGTGAA CTACGTGACC GCGAAGGATG CAGAGAGAGC GATCAACACG
CTGAACGGCT TGAGGCTCCA GTCAAAAACC ATTAAGGTGT CGTATGCTCG CCCGAGCTCA
GAGGTGATCA AAGACGCCAA CTTGTACATC AGCGGGCTCC CGCGGACCAT GACCCAGAAG
GACGTAGAAG ACATGTTCTC TCGGTTTGGG CGGATCATCA ACTCGCGGGT CCTCGTGGAT
CAGACTACAG GTTTGTCCAG AGGGGTTGCG TTTATCCGGT TTGACAAACG GTCGGAGGCA
GAAGAGGCAA TTACCAGTTT CAATGGTCAT AAACCCCCAG GTTCCTCTGA GCCCATCACA
GTGAAGTTTG CAGCCAACCC CAACCAGAAC AAAAACGTGG CACTCCTCTC GCAGCTGTAC
CACTCGCCAG CGCGACGGTT CGGAGGCCCC GTTCACCACC AGGCGCAGAG ATTCAGGTTC
TCCCCCATGG GCGTCGATCA CATGAGCGGG CTCTCTGGCG TCAACGTGCC AGGAAACGCC
TCCTCCGGCT GGTGCATTTT CATCTACAAC CTGGGGCAGG ATGCCGACGA GGGGATCCTC
TGGCAGATGT TTGGGCCGTT TGGTGCCGTC ACCAATGTGA AAGTGATCCG CGACTTCAAC
ACCAACAAGT GCAAAGGGTT TGGCTTTGTG ACCATGACAA ACTATGAAGA AGCCGCGATG
GCCATAGCCA GCCTGAACGG CTACCGCCTG GGGGACAAAA TCTTACAGGT TTCCTTCAAA
ACCAACAAGT CCCACAAATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001410.2
CDS168..1148
Misc Feature(1)171..173(+)
Misc Feature(2)171..173(+)
Misc Feature(3)222..1145(+)
Misc Feature(4)222..455(+)
Misc Feature(5)228..455(+)
Misc Feature(6)483..734(+)
Misc Feature(7)486..722(+)
Misc Feature(8)756..758(+)
Misc Feature(9)765..767(+)
Misc Feature(10)765..767(+)
Misc Feature(11)771..773(+)
Misc Feature(12)771..773(+)
Misc Feature(13)816..818(+)
Misc Feature(14)816..818(+)
Misc Feature(15)894..1145(+)
Exon (1)1..151
Gene:ELAVL1
Gene Synonym:
Exon (2)152..339
Gene:ELAVL1
Gene Synonym:
Exon (3)340..443
Gene:ELAVL1
Gene Synonym:
Exon (4)444..597
Gene:ELAVL1
Gene Synonym:
Exon (5)598..823
Gene:ELAVL1
Gene Synonym:
Exon (6)824..6058
Gene:ELAVL1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001419
Organism Homo sapiens (human)
Definition Homo sapiens ELAV like RNA binding protein 1 (ELAVL1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001419

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCTAATG GTTATGAAGA CCACATGGCC GAAGACTGCA GGGGTGACAT CGGGAGAACG 
AATTTGATCG TCAACTACCT CCCTCAGAAC ATGACCCAGG ATGAGTTACG AAGCCTGTTC
AGCAGCATTG GTGAAGTTGA ATCTGCAAAA CTTATTCGGG ATAAAGTAGC AGGACACAGC
TTGGGCTATG GCTTTGTGAA CTACGTGACC GCGAAGGATG CAGAGAGAGC GATCAACACG
CTGAACGGCT TGAGGCTCCA GTCAAAAACC ATTAAGGTGT CGTATGCTCG CCCGAGCTCA
GAGGTGATCA AAGACGCCAA CTTGTACATC AGCGGGCTCC CGCGGACCAT GACCCAGAAG
GACGTAGAAG ACATGTTCTC TCGGTTTGGG CGGATCATCA ACTCGCGGGT CCTCGTGGAT
CAGACTACAG GTTTGTCCAG AGGGGTTGCG TTTATCCGGT TTGACAAACG GTCGGAGGCA
GAAGAGGCAA TTACCAGTTT CAATGGTCAT AAACCCCCAG GTTCCTCTGA GCCCATCACA
GTGAAGTTTG CAGCCAACCC CAACCAGAAC AAAAACGTGG CACTCCTCTC GCAGCTGTAC
CACTCGCCAG CGCGACGGTT CGGAGGCCCC GTTCACCACC AGGCGCAGAG ATTCAGGTTC
TCCCCCATGG GCGTCGATCA CATGAGCGGG CTCTCTGGCG TCAACGTGCC AGGAAACGCC
TCCTCCGGCT GGTGCATTTT CATCTACAAC CTGGGGCAGG ATGCCGACGA GGGGATCCTC
TGGCAGATGT TTGGGCCGTT TGGTGCCGTC ACCAATGTGA AAGTGATCCG CGACTTCAAC
ACCAACAAGT GCAAAGGGTT TGGCTTTGTG ACCATGACAA ACTATGAAGA AGCCGCGATG
GCCATAGCCA GCCTGAACGG CTACCGCCTG GGGGACAAAA TCTTACAGGT TTCCTTCAAA
ACCAACAAGT CCCACAAATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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