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ERBB2 erb-b2 receptor tyrosine kinase 2 [Homo sapiens (human)]

Gene Symbol ERBB2
Entrez Gene ID 2064
Full Name erb-b2 receptor tyrosine kinase 2
Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
General protein information
Preferred Names
receptor tyrosine-protein kinase erbB-2
Names
receptor tyrosine-protein kinase erbB-2
herstatin
p185erbB2
proto-oncogene Neu
c-erb B2/neu protein
proto-oncogene c-ErbB-2
metastatic lymph node gene 19 protein
neuro/glioblastoma derived oncogene homolog
tyrosine kinase-type cell surface receptor HER2
neuroblastoma/glioblastoma derived oncogene homolog
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
NP_001005862.1
NP_004439.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q12

Summary This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

164870

Disorder Html: Adenocarcinoma of lung, somatic, 211980 (3); Glioblastoma, somatic,





The following ERBB2 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ERBB2 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu24035 NM_001289937 Homo sapiens erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu27656 NM_004448 Homo sapiens erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$1269
OHu27580 NM_001005862 Homo sapiens erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$1239
OHu27526 NM_001289938 Homo sapiens erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $439
OHu23956 NM_001289936 Homo sapiens erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu24035
Accession Version NM_001289937.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3168bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product receptor tyrosine-protein kinase erbB-2 isoform d precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC346286.1, AK313683.1, BC080193.1 and BM678576.1. Summary: This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (4) lacks an exon in the 3' coding region, which results in a translational frameshift, compared to variant 1. The resulting isoform (d) has a distinct and shorter C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK313683.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 10446211 ##RefSeq-Attributes-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
ATGGAGCTGG CGGCCTTGTG CCGCTGGGGG CTCCTCCTCG CCCTCTTGCC CCCCGGAGCC 
GCGAGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTGC GGCTCCCTGC CAGTCCCGAG
ACCCACCTGG ACATGCTCCG CCACCTCTAC CAGGGCTGCC AGGTGGTGCA GGGAAACCTG
GAACTCACCT ACCTGCCCAC CAATGCCAGC CTGTCCTTCC TGCAGGATAT CCAGGAGGTG
CAGGGCTACG TGCTCATCGC TCACAACCAA GTGAGGCAGG TCCCACTGCA GAGGCTGCGG
ATTGTGCGAG GCACCCAGCT CTTTGAGGAC AACTATGCCC TGGCCGTGCT AGACAATGGA
GACCCGCTGA ACAATACCAC CCCTGTCACA GGGGCCTCCC CAGGAGGCCT GCGGGAGCTG
CAGCTTCGAA GCCTCACAGA GATCTTGAAA GGAGGGGTCT TGATCCAGCG GAACCCCCAG
CTCTGCTACC AGGACACGAT TTTGTGGAAG GACATCTTCC ACAAGAACAA CCAGCTGGCT
CTCACACTGA TAGACACCAA CCGCTCTCGG GCCTGCCACC CCTGTTCTCC GATGTGTAAG
GGCTCCCGCT GCTGGGGAGA GAGTTCTGAG GATTGTCAGA GCCTGACGCG CACTGTCTGT
GCCGGTGGCT GTGCCCGCTG CAAGGGGCCA CTGCCCACTG ACTGCTGCCA TGAGCAGTGT
GCTGCCGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTCCA CTTCAACCAC
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACAGA CACGTTTGAG
TCCATGCCCA ATCCCGAGGG CCGGTATACA TTCGGCGCCA GCTGTGTGAC TGCCTGTCCC
TACAACTACC TTTCTACGGA CGTGGGATCC TGCACCCTCG TCTGCCCCCT GCACAACCAA
GAGGTGACAG CAGAGGATGG AACACAGCGG TGTGAGAAGT GCAGCAAGCC CTGTGCCCGA
GTGTGCTATG GTCTGGGCAT GGAGCACTTG CGAGAGGTGA GGGCAGTTAC CAGTGCCAAT
ATCCAGGAGT TTGCTGGCTG CAAGAAGATC TTTGGGAGCC TGGCATTTCT GCCGGAGAGC
TTTGATGGGG ACCCAGCCTC CAACACTGCC CCGCTCCAGC CAGAGCAGCT CCAAGTGTTT
GAGACTCTGG AAGAGATCAC AGGTTACCTA TACATCTCAG CATGGCCGGA CAGCCTGCCT
GACCTCAGCG TCTTCCAGAA CCTGCAAGTA ATCCGGGGAC GAATTCTGCA CAATGGCGCC
TACTCGCTGA CCCTGCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC ACTGAGGGAA
CTGGGCAGTG GACTGGCCCT CATCCACCAT AACACCCACC TCTGCTTCGT GCACACGGTG
CCCTGGGACC AGCTCTTTCG GAACCCGCAC CAAGCTCTGC TCCACACTGC CAACCGGCCA
GAGGACGAGT GTGTGGGCGA GGGCCTGGCC TGCCACCAGC TGTGCGCCCG AGGGCACTGC
TGGGGTCCAG GGCCCACCCA GTGTGTCAAC TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC
GTGGAGGAAT GCCGAGTACT GCAGGGGCTC CCCAGGGAGT ATGTGAATGC CAGGCACTGT
TTGCCGTGCC ACCCTGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGTTT TGGACCGGAG
GCTGACCAGT GTGTGGCCTG TGCCCACTAT AAGGACCCTC CCTTCTGCGT GGCCCGCTGC
CCCAGCGGTG TGAAACCTGA CCTCTCCTAC ATGCCCATCT GGAAGTTTCC AGATGAGGAG
GGCGCATGCC AGCCTTGCCC CATCAACTGC ACCCACTCCT GTGTGGACCT GGATGACAAG
GGCTGCCCCG CCGAGCAGAG AGCCAGCCCT CTGACGTCCA TCATCTCTGC GGTGGTTGGC
ATTCTGCTGG TCGTGGTCTT GGGGGTGGTC TTTGGGATCC TCATCAAGCG ACGGCAGCAG
AAGATCCGGA AGTACACGAT GCGGAGACTG CTGCAGGAAA CGGAGCTGGT GGAGCCGCTG
ACACCTAGCG GAGCGATGCC CAACCAGGCG CAGATGCGGA TCCTGAAAGA GACGGAGCTG
AGGAAGGTGA AGGTGCTTGG ATCTGGCGCT TTTGGCACAG TCTACAAGGG CATCTGGATC
CCTGATGGGG AGAATGTGAA AATTCCAGTG GCCATCAAAG TGTTGAGGGA AAACACATCC
CCCAAAGCCA ACAAAGAAAT CTTAGACGAA GCATACGTGA TGGCTGGTGT GGGCTCCCCA
TATGTCTCCC GCCTTCTGGG CATCTGCCTG ACATCCACGG TGCAGCTGGT GACACAGCTT
ATGCCCTATG GCTGCCTCTT AGACCATGTC CGGGAAAACC GCGGACGCCT GGGCTCCCAG
GACCTGCTGA ACTGGTGTAT GCAGATTGCC AAGGGGATGA GCTACCTGGA GGATGTGCGG
CTCGTACACA GGGACTTGGC CGCTCGGAAC GTGCTGGTCA AGAGTCCCAA CCATGTCAAA
ATTACAGACT TCGGGCTGGC TCGGCTGCTG GACATTGACG AGACAGAGTA CCATGCAGAT
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCA TTCTCCGCCG GCGGTTCACC
CACCAGAGTG ATGTGTGGAG TTATGGTGTG ACTGTGTGGG AGCTGATGAC TTTTGGGGCC
AAACCTTACG ATGGGATCCC AGCCCGGGAG ATCCCTGACC TGCTGGAAAA GGGGGAGCGG
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA ATGTTGGATG
ATTGACTCTG AATGTCGGCC AAGATTCCGG GAGTTGGTGT CTGAATTCTC CCGCATGGCC
AGGGACCCCC AGCGCTTTGT GGTCATCCAG AATGAGGACT TGGGCCCAGC CAGTCCCTTG
GACAGCACCT TCTACCGCTC ACTGCTGGAG GACGATGACA TGGGGGACCT GGTGGATGCT
GAGGAGTATC TGGTACCCCA GCAGGGCTTC TTCTGTCCAG ACCCTGCCCC GGGCGCTGGG
GGCATGGTCC ACCACAGGCA CCGCAGCTCA TCTACCAGGA ATATGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001276866.1
CDS262..3429
Misc Feature(1)236..256(+)
Misc Feature(2)415..780(+)
Misc Feature(3)826..1290(+)
Misc Feature(4)964..1101(+)
Misc Feature(5)1357..1719(+)
Misc Feature(6)1789..>1893(+)
Misc Feature(7)1792..2190(+)
Misc Feature(8)1945..2082(+)
Misc Feature(9)2182..2313(+)
Misc Feature(10)2188..2262(+)
Misc Feature(11)2191..2274(+)
Misc Feature(12)2218..2286(+)
Misc Feature(13)2287..2328(+)
Misc Feature(14)2287..2328(+)
Misc Feature(15)2395..3231(+)
Misc Feature(16)2419..3189(+)
Misc Feature(17)2437..2952(+)
Misc Feature(18)2437..2850(+)
Misc Feature(19)2845..2922(+)
Misc Feature(20)2911..2952(+)
Misc Feature(21)3421..3423(+)
Exon (1)1..334
Gene:ERBB2
Gene Synonym:
Exon (2)335..486
Gene:ERBB2
Gene Synonym:
Exon (3)487..700
Gene:ERBB2
Gene Synonym:
Exon (4)701..835
Gene:ERBB2
Gene Synonym:
Exon (5)836..904
Gene:ERBB2
Gene Synonym:
Exon (6)905..1020
Gene:ERBB2
Gene Synonym:
Exon (7)1021..1162
Gene:ERBB2
Gene Synonym:
Exon (8)1163..1282
Gene:ERBB2
Gene Synonym:
Exon (9)1283..1409
Gene:ERBB2
Gene Synonym:
Exon (10)1410..1483
Gene:ERBB2
Gene Synonym:
Exon (11)1484..1574
Gene:ERBB2
Gene Synonym:
Exon (12)1575..1774
Gene:ERBB2
Gene Synonym:
Exon (13)1775..1907
Gene:ERBB2
Gene Synonym:
Exon (14)1908..1998
Gene:ERBB2
Gene Synonym:
Exon (15)1999..2159
Gene:ERBB2
Gene Synonym:
Exon (16)2160..2207
Gene:ERBB2
Gene Synonym:
Exon (17)2208..2346
Gene:ERBB2
Gene Synonym:
Exon (18)2347..2469
Gene:ERBB2
Gene Synonym:
Exon (19)2470..2568
Gene:ERBB2
Gene Synonym:
Exon (20)2569..2754
Gene:ERBB2
Gene Synonym:
Exon (21)2755..2910
Gene:ERBB2
Gene Synonym:
Exon (22)2911..2986
Gene:ERBB2
Gene Synonym:
Exon (23)2987..3133
Gene:ERBB2
Gene Synonym:
Exon (24)3134..3231
Gene:ERBB2
Gene Synonym:
Exon (25)3232..3420
Gene:ERBB2
Gene Synonym:
Exon (26)3421..4394
Gene:ERBB2
Gene Synonym:
Translation
Position Chain Variation Link
3 3 c, t dbSNP:528194999
17 17 a, c dbSNP:761043239
26 26 a, g dbSNP:540373743
36 36 a, g dbSNP:538872680
49 49 c, t dbSNP:764665578
95 95 c, t dbSNP:528930915
96 96 c, t dbSNP:550828061
102 102 c, t dbSNP:375591649
103 103 a, g dbSNP:569077403
189 189 a, g dbSNP:533116130
211 211 c, t dbSNP:762295163
216 216 a, t dbSNP:551298195
221 221 c, g dbSNP:779641368
225 225 c, t dbSNP:748926804
231 231 c, g dbSNP:768240855
234 234 c, t dbSNP:566910530
250 250 g, t dbSNP:773855470
258 258 c, g dbSNP:572294002
304 304 c, t dbSNP:193171026
312 312 a, c dbSNP:567022720
330 330 c, t dbSNP:773744480
335 335 c, t dbSNP:755921683
340 340 a, c dbSNP:779913120
342 342 c, t dbSNP:377542789
343 343 a, g dbSNP:564064363
345 345 c, g dbSNP:528118039
349 349 g, t dbSNP:778487069
354 354 g, t dbSNP:546886845
358 358 c, t dbSNP:771576995
360 360 a, g dbSNP:4252610
361 361 c, t dbSNP:149937802
363 363 a, g dbSNP:369293607
365 365 c, t dbSNP:777171280
366 366 c, t dbSNP:759935065
370 370 c, g dbSNP:765607521
378 378 c, t dbSNP:775826753
379 379 a, g dbSNP:763193414
394 394 a, g dbSNP:587778266
398 398 c, t dbSNP:764222200
401 401 a, g dbSNP:144019910
431 431 a, g dbSNP:140441229
442 442 c, g dbSNP:766186178
449 449 c, t dbSNP:753655456
453 453 c, t dbSNP:754742686
460 460 a, g dbSNP:778575008
461 461 c, t dbSNP:752339377
464 464 a, g dbSNP:757899978
467 467 c, g dbSNP:777347427
471 471 -, c dbSNP:754691039
486 486 -, g dbSNP:780661804
497 497 a, c dbSNP:61737968
510 510 c, t dbSNP:191376350
511 511 a, g dbSNP:376524324
517 517 a, g dbSNP:759478535
519 519 c, t dbSNP:147785188
520 520 a, g dbSNP:775382058
525 525 a, c dbSNP:762638680
530 530 a, c dbSNP:763850846
534 534 a, g dbSNP:369499945
543 543 a, c dbSNP:756850857
545 545 c, t dbSNP:767151455
559 559 c, t dbSNP:749886389
560 560 a, g dbSNP:756720659
563 563 c, t dbSNP:539140755
573 573 c, t dbSNP:576471733
590 590 a, g dbSNP:749711404
594 594 c, t dbSNP:755265117
601 601 c, t dbSNP:372811772
605 605 c, t dbSNP:748301823
606 606 c, t dbSNP:200102353
612 612 a, g dbSNP:370676964
618 618 c, t dbSNP:747047846
622 622 a, g dbSNP:769775277
625 625 c, g dbSNP:141135746
626 626 c, t dbSNP:370959592
627 627 a, g dbSNP:762875937
628 628 c, t dbSNP:763786330
642 642 c, g dbSNP:4252613
643 643 c, g dbSNP:761564667
644 644 c, g dbSNP:373824622
645 645 c, g, t dbSNP:749976401
646 646 g, t dbSNP:766949725
661 661 c, t dbSNP:754295165
667 667 a, g dbSNP:755427616
671 671 c, t dbSNP:200208742
673 673 c, t dbSNP:779156384
674 674 a, g dbSNP:748476466
678 678 g, t dbSNP:758646541
689 689 a, g dbSNP:185670819
694 694 c, t dbSNP:527779103
713 713 g, t dbSNP:200963868
716 716 c, g dbSNP:151122410
717 717 a, g dbSNP:758734557
718 718 c, g dbSNP:778041266
720 720 c, t dbSNP:751770717
723 723 c, g dbSNP:757446217
730 730 c, t dbSNP:781137961
731 731 a, g dbSNP:745921471
735 735 c, t dbSNP:768502081
736 736 a, c dbSNP:778888794
742 742 c, g dbSNP:774604250
747 747 c, t dbSNP:775319988
752 752 a, g dbSNP:747995543
754 754 c, g dbSNP:771986239
759 759 a, g dbSNP:370810322
783 783 c, t dbSNP:141086703
789 789 c, t dbSNP:56114611
791 791 a, g dbSNP:776032539
798 798 a, g dbSNP:146844678
823 823 a, c, t dbSNP:765706190
824 824 a, g dbSNP:763371007
829 829 c, t dbSNP:753419830
830 830 a, g dbSNP:531563820
840 840 c, g, t dbSNP:769335702
841 841 c, t dbSNP:763458661
842 842 c, t dbSNP:764545872
851 851 c, t dbSNP:113619125
852 852 a, g dbSNP:762217415
855 855 a, g dbSNP:767673890
863 863 g, t dbSNP:750651941
891 891 a, g dbSNP:756204333
894 894 c, t dbSNP:766580117
902 902 g, t dbSNP:753902254
904 904 c, t dbSNP:577260523
908 908 c, t dbSNP:770976272
909 909 a, g dbSNP:779058669
910 910 c, t dbSNP:768151310
911 911 a, g dbSNP:779346332
924 924 c, t dbSNP:748701236
925 925 a, g dbSNP:772393268
936 936 c, g dbSNP:140636713
937 937 c, t dbSNP:760895559
938 938 a, g dbSNP:745625627
949 949 c, t dbSNP:776960538
955 955 a, c dbSNP:759753872
978 978 a, g dbSNP:765424712
982 982 a, g dbSNP:752656997
988 988 a, g dbSNP:533090552
989 989 g, t dbSNP:767309845
995 995 c, t dbSNP:376183465
996 996 a, g dbSNP:755873891
1009 1009 c, t dbSNP:779750598
1028 1028 c, t dbSNP:777081311
1029 1029 c, t dbSNP:759845382
1037 1037 a, g dbSNP:769870618
1038 1038 c, t dbSNP:775666242
1039 1039 c, t dbSNP:762919589
1046 1046 a, g dbSNP:548076348
1048 1048 a, t dbSNP:750324803
1050 1050 c, t dbSNP:760523023
1053 1053 c, t dbSNP:368210132
1056 1056 a, g dbSNP:530186646
1060 1060 c, t dbSNP:773759626
1069 1069 g, t dbSNP:200382130
1070 1070 c, t dbSNP:754656388
1071 1071 c, t dbSNP:764747320
1079 1079 c, t dbSNP:752295912
1094 1094 a, c dbSNP:757811990
1105 1105 a, c dbSNP:778408285
1116 1116 c, t dbSNP:747503021
1117 1117 a, g dbSNP:149210045
1124 1124 a, g dbSNP:760205387
1129 1129 a, g dbSNP:746190897
1134 1134 c, t dbSNP:770104901
1135 1135 a, g dbSNP:775544453
1137 1137 c, t dbSNP:749453104
1166 1166 a, t dbSNP:768855063
1170 1170 c, t dbSNP:774443757
1173 1173 c, t dbSNP:748176467
1182 1182 c, t dbSNP:770903497
1183 1183 a, g dbSNP:776515406
1188 1188 a, t dbSNP:145697136
1200 1200 c, t dbSNP:138280629
1201 1201 a, g dbSNP:775294491
1213 1213 c, t dbSNP:762547363
1227 1227 g, t dbSNP:546000185
1244 1244 a, c, t dbSNP:763793826
1249 1249 c, t dbSNP:761376658
1250 1250 a, g dbSNP:768206712
1253 1253 a, g dbSNP:564382616
1257 1257 a, g dbSNP:756588194
1260 1260 a, g dbSNP:780283935
1262 1262 -, g dbSNP:769703068
1263 1263 c, t dbSNP:754188777
1280 1280 a, g dbSNP:532077147
1287 1287 c, t dbSNP:778968985
1289 1289 a, g dbSNP:747993530
1291 1291 c, g dbSNP:758204762
1296 1296 a, g dbSNP:777348537
1301 1301 a, t dbSNP:746686273
1309 1309 c, t dbSNP:770421665
1311 1311 a, c, g dbSNP:559242250
1312 1312 a, c dbSNP:770327076
1313 1313 a, g dbSNP:775972596
1316 1316 a, g dbSNP:763367024
1318 1318 g, t dbSNP:769082334
1326 1326 a, g dbSNP:190567339
1340 1340 a, t dbSNP:373474372
1341 1341 c, t dbSNP:762129422
1357 1357 c, g dbSNP:767588058
1359 1359 c, g dbSNP:750577335
1368 1368 a, g dbSNP:760803727
1374 1374 c, t dbSNP:149567593
1384 1384 a, g dbSNP:752664566
1394 1394 c, t dbSNP:758210687
1395 1395 a, g dbSNP:143225142
1399 1399 a, g dbSNP:148068883
1409 1409 a, g dbSNP:751270411
1411 1411 a, g dbSNP:753902259
1413 1413 c, t dbSNP:199514902
1418 1418 a, c, g dbSNP:141116145
1419 1419 c, t dbSNP:756999086
1423 1423 a, c dbSNP:780881510
1424 1424 a, g dbSNP:750090147
1429 1429 a, g dbSNP:755701444
1430 1430 c, t dbSNP:587778264
1431 1431 c, t dbSNP:544011927
1433 1433 c, t dbSNP:748700504
1434 1434 a, c, g dbSNP:769257889
1437 1437 c, g dbSNP:562384569
1440 1440 a, g dbSNP:147204600
1442 1442 c, t dbSNP:772548631
1454 1454 a, g dbSNP:773649491
1456 1456 a, g dbSNP:747239268
1468 1468 a, c, t dbSNP:377649991
1470 1470 a, g dbSNP:776871033
1492 1492 g, t dbSNP:587778265
1495 1495 a, g dbSNP:758908894
1503 1503 a, c, g dbSNP:373728539
1508 1508 c, t dbSNP:747327229
1509 1509 a, g dbSNP:140507994
1511 1511 a, c dbSNP:776714622
1517 1517 g, t dbSNP:746020984
1525 1525 a, c dbSNP:769778398
1528 1528 a, g dbSNP:199668084
1530 1530 c, t dbSNP:35757908
1531 1531 a, g dbSNP:142783371
1549 1549 a, g dbSNP:767398280
1555 1555 c, t dbSNP:367606199
1562 1562 a, g dbSNP:147382623
1570 1570 c, t dbSNP:766083302
1578 1578 c, t dbSNP:750754275
1579 1579 a, g dbSNP:756345214
1581 1581 a, c dbSNP:780294548
1586 1586 c, t dbSNP:749440298
1587 1587 g, t dbSNP:4252632
1593 1593 a, c dbSNP:778904008
1596 1596 a, g dbSNP:746949970
1609 1609 a, g dbSNP:770857517
1617 1617 g, t dbSNP:4252633
1618 1618 c, g dbSNP:759352819
1627 1627 c, t dbSNP:200497646
1632 1632 a, g dbSNP:2230698
1633 1633 c, t dbSNP:368989970
1646 1646 a, g, t dbSNP:373192991
1658 1658 c, t dbSNP:751074421
1670 1670 a, g dbSNP:201097345
1676 1676 c, t dbSNP:768049972
1677 1677 c, t dbSNP:61737967
1678 1678 c, g dbSNP:756500045
1687 1687 g, t dbSNP:780201941
1689 1689 c, t dbSNP:532023577
1690 1690 a, g dbSNP:755121772
1697 1697 c, t dbSNP:201021373
1701 1701 a, g dbSNP:748176472
1703 1703 c, t dbSNP:370565888
1704 1704 c, g, t dbSNP:55984118
1708 1708 a, g dbSNP:571837012
1719 1719 c, t dbSNP:539260608
1720 1720 c, t dbSNP:375382055
1721 1721 a, c, g dbSNP:371450390
1725 1725 a, c dbSNP:768374532
1727 1727 c, t dbSNP:142456637
1728 1728 a, g dbSNP:147076339
1732 1732 c, g, t dbSNP:140670446
1748 1748 c, t dbSNP:767978749
1750 1750 a, g dbSNP:145762641
1756 1756 a, c, g, t dbSNP:199530208
1757 1757 a, g, t dbSNP:182572604
1767 1767 c, t dbSNP:752759368
1768 1768 a, g dbSNP:758497995
1791 1791 c, g dbSNP:765510261
1806 1806 c, t dbSNP:368632077
1807 1807 a, g dbSNP:371623072
1811 1811 a, g dbSNP:759579850
1815 1815 a, g dbSNP:199657476
1826 1826 a, g dbSNP:561322621
1828 1828 c, t dbSNP:202202058
1830 1830 a, g dbSNP:55928971
1839 1839 c, g, t dbSNP:754811013
1846 1846 a, g dbSNP:747838206
1850 1850 a, g dbSNP:771580372
1852 1852 c, t dbSNP:140711914
1855 1855 a, c dbSNP:777363214
1864 1864 c, t dbSNP:746476368
1868 1868 a, g dbSNP:140980495
1875 1875 g, t dbSNP:777116958
1881 1881 c, t dbSNP:371585581
1885 1885 g, t dbSNP:770157051
1893 1893 c, t dbSNP:775678910
1895 1895 a, g dbSNP:150203173
1903 1903 a, c, t dbSNP:565582943
1906 1906 g, t dbSNP:532713027
1908 1908 g, t dbSNP:775974838
1911 1911 c, t dbSNP:763197991
1920 1920 a, g dbSNP:768992351
1923 1923 c, t dbSNP:774426489
1926 1926 a, g dbSNP:762073749
1938 1938 c, g, t dbSNP:767713671
1942 1942 c, t dbSNP:369690252
1946 1946 c, t dbSNP:201470725
1947 1947 a, c, g dbSNP:4252635
1967 1967 c, t dbSNP:763863372
1974 1974 c, t dbSNP:149337787
1976 1976 g, t dbSNP:756836001
1986 1986 a, c, t dbSNP:780703792
1991 1991 g, t dbSNP:778479390
1997 1997 c, t dbSNP:756686824
2007 2007 c, t dbSNP:138893464
2033 2033 a, t dbSNP:767216520
2039 2039 c, t dbSNP:750092447
2042 2042 a, c dbSNP:760310908
2043 2043 a, c dbSNP:765842816
2049 2049 c, t dbSNP:753344199
2050 2050 a, g dbSNP:755483857
2054 2054 a, c, g dbSNP:145409713
2056 2056 c, t dbSNP:369903296
2057 2057 a, g dbSNP:758820578
2058 2058 c, g dbSNP:778223078
2067 2067 c, t dbSNP:747200104
2068 2068 a, g dbSNP:771145294
2069 2069 a, g dbSNP:781179380
2076 2076 a, g dbSNP:538900246
2085 2085 c, t dbSNP:768648444
2089 2089 c, t dbSNP:774261411
2092 2092 a, g dbSNP:377370642
2106 2106 a, g dbSNP:771862037
2118 2118 a, g dbSNP:142816898
2124 2124 c, t dbSNP:760271180
2125 2125 a, g dbSNP:766029214
2127 2127 a, g dbSNP:753325392
2135 2135 c, t dbSNP:759078493
2136 2136 c, t dbSNP:765900638
2146 2146 a, g dbSNP:753267835
2147 2147 a, c dbSNP:758907167
2155 2155 c, t dbSNP:778312796
2159 2159 c, t dbSNP:199726056
2187 2187 c, t dbSNP:541854282
2189 2189 c, g dbSNP:367599823
2190 2190 c, g, t dbSNP:56110910
2191 2191 a, g dbSNP:750665964
2193 2193 c, t dbSNP:141678288
2194 2194 a, g dbSNP:370514427
2201 2201 a, c, g dbSNP:201784472
2203 2203 a, g dbSNP:777759226
2210 2210 c, t dbSNP:778798172
2211 2211 c, t dbSNP:746968535
2212 2212 c, t dbSNP:757101082
2220 2220 c, t dbSNP:374222106
2221 2221 a, c, g dbSNP:1801201
2223 2223 c, t dbSNP:779841027
2224 2224 a, g, t dbSNP:1136201
2226 2226 c, t dbSNP:768217764
2229 2229 g, t dbSNP:577329788
2242 2242 a, g dbSNP:762407538
2253 2253 c, g dbSNP:772440208
2262 2262 a, g dbSNP:773610266
2263 2263 c, g dbSNP:372616729
2265 2265 a, c, g dbSNP:199841166
2296 2296 c, g dbSNP:759608479
2309 2309 c, g dbSNP:765387989
2314 2314 c, t dbSNP:752669313
2343 2343 a, g dbSNP:757266514
2367 2367 c, t dbSNP:762937851
2369 2369 g, t dbSNP:34602395
2370 2370 c, t dbSNP:764211319
2391 2391 a, g dbSNP:750389304
2396 2396 g, t dbSNP:756073738
2399 2399 a, g dbSNP:779034594
2409 2409 a, g dbSNP:146883671
2415 2415 a, g dbSNP:753552215
2419 2419 c, t dbSNP:374098949
2439 2439 c, t dbSNP:778422158
2457 2457 c, t dbSNP:377617979
2464 2464 c, t dbSNP:757863234
2497 2497 a, g dbSNP:781547782
2501 2501 a, c dbSNP:746301859
2524 2524 cc, tt dbSNP:121913469
2525 2525 c, t dbSNP:121913470
2541 2541 c, t dbSNP:779727777
2544 2544 c, t dbSNP:775883027
2553 2553 c, t dbSNP:139745101
2562 2562 a, c dbSNP:768974971
2564 2564 c, t dbSNP:56366519
2566 2566 c, g dbSNP:121913468
2568 2568 c, t dbSNP:774610157
2577 2577 c, t dbSNP:748318804
2578 2578 a, g dbSNP:772054394
2581 2581 -, a dbSNP:397516978
2583 2583 -, gcatacgtgatg dbSNP:397516975
2583 2583 g, t dbSNP:773305795
2585 2585 -, atacgtgatggc, ctccgtgatggc dbSNP:397516976
2586 2586 -, tacgtgatggct, tccgtgatggct dbSNP:397516977
2587 2587 -, tct, tgt, ttt dbSNP:397516979
2587 2587 a, g dbSNP:28933369
2587 2587 g, ttat dbSNP:397516980
2588 2588 a, c, g, t dbSNP:144434331
2590 2590 g, t dbSNP:121913471
2592 2592 -, g dbSNP:748202083
2597 2597 -, tgtgggctc dbSNP:587776805
2597 2597 c, t dbSNP:775190312
2598 2598 c, t dbSNP:762733948
2600 2600 -, gggctcccc dbSNP:397516981
2601 2601 -, ggctcccca dbSNP:397516982
2610 2610 c, t dbSNP:763795273
2612 2612 a, g dbSNP:751226373
2629 2629 c, t dbSNP:761415465
2639 2639 c, t dbSNP:766958268
2640 2640 a, g dbSNP:186232310
2646 2646 a, g dbSNP:756617192
2652 2652 a, g dbSNP:368499773
2661 2661 c, t dbSNP:754308267
2669 2669 a, g dbSNP:755402782
2685 2685 a, c dbSNP:146603731
2692 2692 c, t dbSNP:748416534
2693 2693 a, g dbSNP:775752713
2701 2701 c, t dbSNP:587778267
2703 2703 c, t dbSNP:553270501
2704 2704 a, g dbSNP:368094521
2707 2707 c, t dbSNP:542027040
2708 2708 a, g dbSNP:775394020
2709 2709 a, c dbSNP:762819802
2712 2712 a, g, t dbSNP:768470177
2730 2730 a, g dbSNP:557172740
2745 2745 c, g dbSNP:767164590
2767 2767 c, t dbSNP:104886008
2769 2769 a, g dbSNP:149176913
2779 2779 c, t dbSNP:369828131
2780 2780 a, g dbSNP:747967722
2781 2781 a, g dbSNP:104886011
2784 2784 c, t dbSNP:373165016
2796 2796 c, t dbSNP:137852788
2797 2797 c, t dbSNP:370816244
2802 2802 c, t dbSNP:140231769
2808 2808 a, g dbSNP:766022187
2811 2811 c, t dbSNP:776236294
2812 2812 a, g dbSNP:375043510
2824 2824 a, g dbSNP:765811300
2829 2829 c, t dbSNP:104886009
2831 2831 a, g dbSNP:28933370
2835 2835 c, t dbSNP:377653295
2847 2847 a, t dbSNP:758778485
2850 2850 c, t dbSNP:764308274
2853 2853 c, t dbSNP:151263346
2866 2866 c, t dbSNP:104886010
2871 2871 a, g dbSNP:757372006
2875 2875 a, g, t dbSNP:371081280
2880 2880 c, t dbSNP:540921632
2881 2881 a, g dbSNP:375637720
2899 2899 c, g dbSNP:747974836
2916 2916 c, t dbSNP:756196886
2917 2917 a, g dbSNP:780037152
2931 2931 a, g dbSNP:140453509
2947 2947 c, t dbSNP:758222990
2948 2948 a, g dbSNP:777677468
2949 2949 c, t dbSNP:369203202
2950 2950 c, t dbSNP:375135008
2955 2955 a, g dbSNP:199638358
2961 2961 c, g dbSNP:370134709
2966 2966 a, c dbSNP:188440186
2967 2967 c, g dbSNP:193920750
2976 2976 a, g dbSNP:769432866
2988 2988 g, t dbSNP:760843554
2991 2991 a, g dbSNP:766499882
3001 3001 a, g dbSNP:28933368
3026 3026 c, g dbSNP:753844448
3030 3030 c, t dbSNP:147028804
3031 3031 a, g dbSNP:777570707
3036 3036 c, g dbSNP:575812477
3045 3045 c, t dbSNP:757132983
3046 3046 c, t dbSNP:781070018
3047 3047 a, g dbSNP:201399875
3051 3051 g, t dbSNP:138957632
3057 3057 c, t dbSNP:779653888
3082 3082 c, t dbSNP:748743338
3085 3085 c, g, t dbSNP:769262054
3087 3087 c, t dbSNP:141423785
3094 3094 c, t dbSNP:772452342
3096 3096 -, t dbSNP:774137752
3096 3096 a, c, g dbSNP:543123530
3112 3112 a, g dbSNP:766483219
3119 3119 -, tgatcatgg dbSNP:745798193
3135 3135 c, t dbSNP:775663547
3143 3143 c, t dbSNP:761891977
3144 3144 g, t dbSNP:767556375
3146 3146 a, g dbSNP:750299289
3151 3151 c, g dbSNP:767813285
3157 3157 c, t dbSNP:753151506
3158 3158 a, g dbSNP:755874371
3169 3169 c, t dbSNP:766129765
3170 3170 a, g dbSNP:753460336
3175 3175 c, t dbSNP:201193677
3176 3176 c, t dbSNP:778440239
3183 3183 c, t dbSNP:747628943
3193 3193 c, t dbSNP:758973569
3194 3194 a, g dbSNP:778243900
3196 3196 a, g dbSNP:747461130
3214 3214 c, t dbSNP:771206209
3226 3226 a, c, g dbSNP:202110098
3242 3242 c, t dbSNP:774636044
3251 3251 a, c dbSNP:752037952
3252 3252 c, t dbSNP:757734622
3260 3260 c, t dbSNP:781460225
3262 3262 g, t dbSNP:746213900
3267 3267 c, t dbSNP:770197622
3277 3277 c, t dbSNP:780434636
3278 3278 a, g dbSNP:749454186
3285 3285 a, g dbSNP:765296069
3294 3294 c, t dbSNP:373188896
3295 3295 a, g dbSNP:774520188
3301 3301 a, g dbSNP:760573708
3305 3305 a, g dbSNP:140272156
3320 3320 c, g dbSNP:776359403
3331 3331 c, t dbSNP:4252654
3338 3338 a, c dbSNP:192441765
3339 3339 c, t dbSNP:4252655
3341 3341 -, agcaggg dbSNP:760152942
3350 3350 g, t dbSNP:762553217
3368 3368 c, t dbSNP:763617317
3369 3369 c, t dbSNP:545969208
3371 3371 c, t dbSNP:201905649
3372 3372 a, g dbSNP:781713745
3375 3375 c, t dbSNP:766276087
3376 3376 a, g dbSNP:566053951
3396 3396 c, g dbSNP:756551038
3403 3403 c, t dbSNP:377602610
3404 3404 a, g dbSNP:749539903
3407 3407 a, g dbSNP:104886025
3410 3410 c, t dbSNP:199905364
3411 3411 a, t dbSNP:748251749
3413 3413 a, c dbSNP:139630504
3417 3417 c, g dbSNP:561720540
3418 3418 a, g dbSNP:370561486
3425 3425 c, t dbSNP:770391447
3426 3426 a, g dbSNP:775877222
3431 3431 a, c dbSNP:146177313
3435 3435 a, c dbSNP:587778268
3436 3436 c, t dbSNP:587778269
3437 3437 a, g dbSNP:769929665
3438 3438 c, g dbSNP:138611862
3444 3444 c, t dbSNP:762062043
3445 3445 a, g dbSNP:767717383
3446 3446 a, g dbSNP:370079170
3449 3449 a, c, t dbSNP:112561362
3456 3456 c, g dbSNP:562773948
3458 3458 c, t dbSNP:760679991
3461 3461 a, g dbSNP:144501267
3464 3464 c, t dbSNP:551805660
3466 3466 a, g dbSNP:758365405
3467 3467 a, c dbSNP:567023682
3471 3471 a, g, t dbSNP:751372943
3478 3478 g, t dbSNP:757037466
3482 3482 g, t dbSNP:373365159
3490 3490 a, g dbSNP:150680317
3491 3491 a, g dbSNP:755586442
3492 3492 c, t dbSNP:201482456
3509 3509 a, g dbSNP:749807221
3515 3515 a, g dbSNP:769120310
3516 3516 c, g dbSNP:1058808
3527 3527 c, t dbSNP:748495392
3537 3537 a, t dbSNP:772360944
3539 3539 a, g, t dbSNP:4252656
3546 3546 -, gtc dbSNP:751889439
3548 3548 c, t dbSNP:759480536
3549 3549 a, g dbSNP:776754071
3552 3552 a, c dbSNP:763027953
3553 3553 a, g dbSNP:764123297
3557 3557 c, t dbSNP:767230649
3558 3558 a, g dbSNP:761715861
3578 3578 c, t dbSNP:149815705
3581 3581 a, g dbSNP:750063274
3582 3582 g, t dbSNP:182815010
3590 3590 c, t dbSNP:755767616
3603 3603 a, c dbSNP:779469693
3618 3618 a, g dbSNP:753337412
3619 3619 c, g dbSNP:373605104
3620 3620 c, t dbSNP:755536204
3621 3621 c, t dbSNP:201353217
3628 3628 c, t dbSNP:145772320
3638 3638 c, t dbSNP:141627242
3655 3655 a, c dbSNP:55943169
3657 3657 c, t dbSNP:747245215
3659 3659 c, t dbSNP:188050006
3670 3670 a, g dbSNP:568793816
3677 3677 -, ggacca dbSNP:755472707
3684 3684 a, g dbSNP:539683889
3696 3696 -, g dbSNP:768092215
3696 3696 c, t dbSNP:769940977
3697 3697 a, c, g, t dbSNP:372043866
3713 3713 c, t dbSNP:4252657
3714 3714 a, t dbSNP:750197828
3724 3724 a, g dbSNP:760307857
3726 3726 a, c dbSNP:766037507
3729 3729 c, t dbSNP:753431083
3730 3730 c, g dbSNP:141494080
3733 3733 c, t dbSNP:778352367
3734 3734 a, g dbSNP:753222413
3738 3738 a, g dbSNP:144533600
3745 3745 -, a dbSNP:752875197
3745 3745 c, t dbSNP:375408471
3749 3749 a, g dbSNP:368770921
3751 3751 a, g dbSNP:771116500
3752 3752 c, t dbSNP:781493914
3761 3761 a, g dbSNP:746024186
3762 3762 a, g dbSNP:184203026
3764 3764 c, t dbSNP:775687641
3765 3765 a, g dbSNP:36085723
3770 3770 a, c dbSNP:761879528
3771 3771 g, t dbSNP:755744500
3772 3772 c, t dbSNP:772934121
3781 3781 a, g, t dbSNP:2230700
3782 3782 a, c, g dbSNP:376055107
3783 3783 a, c, g dbSNP:759138887
3793 3793 c, t dbSNP:369214536
3794 3794 a, g dbSNP:763698349
3799 3799 a, c dbSNP:764649330
3801 3801 a, c dbSNP:777932453
3808 3808 a, g dbSNP:751957841
3813 3813 c, t dbSNP:772864303
3816 3816 -, ag dbSNP:756233934
3824 3824 c, g dbSNP:562868556
3826 3826 a, g dbSNP:192237900
3832 3832 c, g dbSNP:545634588
3833 3833 c, t dbSNP:560774319
3842 3842 c, t dbSNP:4252658
3850 3850 -, a dbSNP:537313073
3851 3851 -, a dbSNP:4252659
3898 3898 -, g dbSNP:36042695
3903 3903 c, t dbSNP:549594933
3936 3936 -, c dbSNP:35040721
3960 3960 c, g dbSNP:567252769
3972 3972 g, t dbSNP:756776172
3977 3977 a, t dbSNP:189417058
4003 4003 c, g dbSNP:550418471
4011 4011 c, g dbSNP:778498515
4033 4033 c, t dbSNP:139158322
4062 4062 c, t dbSNP:747455080
4097 4097 a, g dbSNP:539073563
4101 4101 c, g dbSNP:755575307
4106 4106 a, c dbSNP:781648400
4119 4119 c, t dbSNP:748570170
4152 4152 c, g dbSNP:762528320
4189 4189 c, g dbSNP:4252660
4212 4212 c, g dbSNP:377267613
4235 4235 a, g dbSNP:770027275
4240 4240 c, g dbSNP:530844735
4254 4254 -, t dbSNP:755980905
4275 4275 g, t dbSNP:749371173
4337 4337 a, g dbSNP:552475695
4367 4367 c, t dbSNP:4252661
4377 4377 c, t dbSNP:774416904

Target ORF information:

RefSeq Version NM_001289937
Organism Homo sapiens (human)
Definition Homo sapiens erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001289937

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
ATGGAGCTGG CGGCCTTGTG CCGCTGGGGG CTCCTCCTCG CCCTCTTGCC CCCCGGAGCC 
GCGAGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTGC GGCTCCCTGC CAGTCCCGAG
ACCCACCTGG ACATGCTCCG CCACCTCTAC CAGGGCTGCC AGGTGGTGCA GGGAAACCTG
GAACTCACCT ACCTGCCCAC CAATGCCAGC CTGTCCTTCC TGCAGGATAT CCAGGAGGTG
CAGGGCTACG TGCTCATCGC TCACAACCAA GTGAGGCAGG TCCCACTGCA GAGGCTGCGG
ATTGTGCGAG GCACCCAGCT CTTTGAGGAC AACTATGCCC TGGCCGTGCT AGACAATGGA
GACCCGCTGA ACAATACCAC CCCTGTCACA GGGGCCTCCC CAGGAGGCCT GCGGGAGCTG
CAGCTTCGAA GCCTCACAGA GATCTTGAAA GGAGGGGTCT TGATCCAGCG GAACCCCCAG
CTCTGCTACC AGGACACGAT TTTGTGGAAG GACATCTTCC ACAAGAACAA CCAGCTGGCT
CTCACACTGA TAGACACCAA CCGCTCTCGG GCCTGCCACC CCTGTTCTCC GATGTGTAAG
GGCTCCCGCT GCTGGGGAGA GAGTTCTGAG GATTGTCAGA GCCTGACGCG CACTGTCTGT
GCCGGTGGCT GTGCCCGCTG CAAGGGGCCA CTGCCCACTG ACTGCTGCCA TGAGCAGTGT
GCTGCCGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTCCA CTTCAACCAC
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACAGA CACGTTTGAG
TCCATGCCCA ATCCCGAGGG CCGGTATACA TTCGGCGCCA GCTGTGTGAC TGCCTGTCCC
TACAACTACC TTTCTACGGA CGTGGGATCC TGCACCCTCG TCTGCCCCCT GCACAACCAA
GAGGTGACAG CAGAGGATGG AACACAGCGG TGTGAGAAGT GCAGCAAGCC CTGTGCCCGA
GTGTGCTATG GTCTGGGCAT GGAGCACTTG CGAGAGGTGA GGGCAGTTAC CAGTGCCAAT
ATCCAGGAGT TTGCTGGCTG CAAGAAGATC TTTGGGAGCC TGGCATTTCT GCCGGAGAGC
TTTGATGGGG ACCCAGCCTC CAACACTGCC CCGCTCCAGC CAGAGCAGCT CCAAGTGTTT
GAGACTCTGG AAGAGATCAC AGGTTACCTA TACATCTCAG CATGGCCGGA CAGCCTGCCT
GACCTCAGCG TCTTCCAGAA CCTGCAAGTA ATCCGGGGAC GAATTCTGCA CAATGGCGCC
TACTCGCTGA CCCTGCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC ACTGAGGGAA
CTGGGCAGTG GACTGGCCCT CATCCACCAT AACACCCACC TCTGCTTCGT GCACACGGTG
CCCTGGGACC AGCTCTTTCG GAACCCGCAC CAAGCTCTGC TCCACACTGC CAACCGGCCA
GAGGACGAGT GTGTGGGCGA GGGCCTGGCC TGCCACCAGC TGTGCGCCCG AGGGCACTGC
TGGGGTCCAG GGCCCACCCA GTGTGTCAAC TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC
GTGGAGGAAT GCCGAGTACT GCAGGGGCTC CCCAGGGAGT ATGTGAATGC CAGGCACTGT
TTGCCGTGCC ACCCTGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGTTT TGGACCGGAG
GCTGACCAGT GTGTGGCCTG TGCCCACTAT AAGGACCCTC CCTTCTGCGT GGCCCGCTGC
CCCAGCGGTG TGAAACCTGA CCTCTCCTAC ATGCCCATCT GGAAGTTTCC AGATGAGGAG
GGCGCATGCC AGCCTTGCCC CATCAACTGC ACCCACTCCT GTGTGGACCT GGATGACAAG
GGCTGCCCCG CCGAGCAGAG AGCCAGCCCT CTGACGTCCA TCATCTCTGC GGTGGTTGGC
ATTCTGCTGG TCGTGGTCTT GGGGGTGGTC TTTGGGATCC TCATCAAGCG ACGGCAGCAG
AAGATCCGGA AGTACACGAT GCGGAGACTG CTGCAGGAAA CGGAGCTGGT GGAGCCGCTG
ACACCTAGCG GAGCGATGCC CAACCAGGCG CAGATGCGGA TCCTGAAAGA GACGGAGCTG
AGGAAGGTGA AGGTGCTTGG ATCTGGCGCT TTTGGCACAG TCTACAAGGG CATCTGGATC
CCTGATGGGG AGAATGTGAA AATTCCAGTG GCCATCAAAG TGTTGAGGGA AAACACATCC
CCCAAAGCCA ACAAAGAAAT CTTAGACGAA GCATACGTGA TGGCTGGTGT GGGCTCCCCA
TATGTCTCCC GCCTTCTGGG CATCTGCCTG ACATCCACGG TGCAGCTGGT GACACAGCTT
ATGCCCTATG GCTGCCTCTT AGACCATGTC CGGGAAAACC GCGGACGCCT GGGCTCCCAG
GACCTGCTGA ACTGGTGTAT GCAGATTGCC AAGGGGATGA GCTACCTGGA GGATGTGCGG
CTCGTACACA GGGACTTGGC CGCTCGGAAC GTGCTGGTCA AGAGTCCCAA CCATGTCAAA
ATTACAGACT TCGGGCTGGC TCGGCTGCTG GACATTGACG AGACAGAGTA CCATGCAGAT
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCA TTCTCCGCCG GCGGTTCACC
CACCAGAGTG ATGTGTGGAG TTATGGTGTG ACTGTGTGGG AGCTGATGAC TTTTGGGGCC
AAACCTTACG ATGGGATCCC AGCCCGGGAG ATCCCTGACC TGCTGGAAAA GGGGGAGCGG
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA ATGTTGGATG
ATTGACTCTG AATGTCGGCC AAGATTCCGG GAGTTGGTGT CTGAATTCTC CCGCATGGCC
AGGGACCCCC AGCGCTTTGT GGTCATCCAG AATGAGGACT TGGGCCCAGC CAGTCCCTTG
GACAGCACCT TCTACCGCTC ACTGCTGGAG GACGATGACA TGGGGGACCT GGTGGATGCT
GAGGAGTATC TGGTACCCCA GCAGGGCTTC TTCTGTCCAG ACCCTGCCCC GGGCGCTGGG
GGCATGGTCC ACCACAGGCA CCGCAGCTCA TCTACCAGGA ATATGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27656
Accession Version NM_004448.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3768bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu27656D_COA.pdf (pdf)
Update Date 15-MAY-2015
Organism Homo sapiens (human)
Product receptor tyrosine-protein kinase erbB-2 isoform a precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC346286.1, X03363.1 and BM678576.1. This sequence is a reference standard in the RefSeqGene project. On Feb 11, 2014 this sequence version replaced gi:54792095. Summary: This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M11730.1, X03363.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 10446211 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
ATGGAGCTGG CGGCCTTGTG CCGCTGGGGG CTCCTCCTCG CCCTCTTGCC CCCCGGAGCC 
GCGAGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTGC GGCTCCCTGC CAGTCCCGAG
ACCCACCTGG ACATGCTCCG CCACCTCTAC CAGGGCTGCC AGGTGGTGCA GGGAAACCTG
GAACTCACCT ACCTGCCCAC CAATGCCAGC CTGTCCTTCC TGCAGGATAT CCAGGAGGTG
CAGGGCTACG TGCTCATCGC TCACAACCAA GTGAGGCAGG TCCCACTGCA GAGGCTGCGG
ATTGTGCGAG GCACCCAGCT CTTTGAGGAC AACTATGCCC TGGCCGTGCT AGACAATGGA
GACCCGCTGA ACAATACCAC CCCTGTCACA GGGGCCTCCC CAGGAGGCCT GCGGGAGCTG
CAGCTTCGAA GCCTCACAGA GATCTTGAAA GGAGGGGTCT TGATCCAGCG GAACCCCCAG
CTCTGCTACC AGGACACGAT TTTGTGGAAG GACATCTTCC ACAAGAACAA CCAGCTGGCT
CTCACACTGA TAGACACCAA CCGCTCTCGG GCCTGCCACC CCTGTTCTCC GATGTGTAAG
GGCTCCCGCT GCTGGGGAGA GAGTTCTGAG GATTGTCAGA GCCTGACGCG CACTGTCTGT
GCCGGTGGCT GTGCCCGCTG CAAGGGGCCA CTGCCCACTG ACTGCTGCCA TGAGCAGTGT
GCTGCCGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTCCA CTTCAACCAC
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACAGA CACGTTTGAG
TCCATGCCCA ATCCCGAGGG CCGGTATACA TTCGGCGCCA GCTGTGTGAC TGCCTGTCCC
TACAACTACC TTTCTACGGA CGTGGGATCC TGCACCCTCG TCTGCCCCCT GCACAACCAA
GAGGTGACAG CAGAGGATGG AACACAGCGG TGTGAGAAGT GCAGCAAGCC CTGTGCCCGA
GTGTGCTATG GTCTGGGCAT GGAGCACTTG CGAGAGGTGA GGGCAGTTAC CAGTGCCAAT
ATCCAGGAGT TTGCTGGCTG CAAGAAGATC TTTGGGAGCC TGGCATTTCT GCCGGAGAGC
TTTGATGGGG ACCCAGCCTC CAACACTGCC CCGCTCCAGC CAGAGCAGCT CCAAGTGTTT
GAGACTCTGG AAGAGATCAC AGGTTACCTA TACATCTCAG CATGGCCGGA CAGCCTGCCT
GACCTCAGCG TCTTCCAGAA CCTGCAAGTA ATCCGGGGAC GAATTCTGCA CAATGGCGCC
TACTCGCTGA CCCTGCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC ACTGAGGGAA
CTGGGCAGTG GACTGGCCCT CATCCACCAT AACACCCACC TCTGCTTCGT GCACACGGTG
CCCTGGGACC AGCTCTTTCG GAACCCGCAC CAAGCTCTGC TCCACACTGC CAACCGGCCA
GAGGACGAGT GTGTGGGCGA GGGCCTGGCC TGCCACCAGC TGTGCGCCCG AGGGCACTGC
TGGGGTCCAG GGCCCACCCA GTGTGTCAAC TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC
GTGGAGGAAT GCCGAGTACT GCAGGGGCTC CCCAGGGAGT ATGTGAATGC CAGGCACTGT
TTGCCGTGCC ACCCTGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGTTT TGGACCGGAG
GCTGACCAGT GTGTGGCCTG TGCCCACTAT AAGGACCCTC CCTTCTGCGT GGCCCGCTGC
CCCAGCGGTG TGAAACCTGA CCTCTCCTAC ATGCCCATCT GGAAGTTTCC AGATGAGGAG
GGCGCATGCC AGCCTTGCCC CATCAACTGC ACCCACTCCT GTGTGGACCT GGATGACAAG
GGCTGCCCCG CCGAGCAGAG AGCCAGCCCT CTGACGTCCA TCATCTCTGC GGTGGTTGGC
ATTCTGCTGG TCGTGGTCTT GGGGGTGGTC TTTGGGATCC TCATCAAGCG ACGGCAGCAG
AAGATCCGGA AGTACACGAT GCGGAGACTG CTGCAGGAAA CGGAGCTGGT GGAGCCGCTG
ACACCTAGCG GAGCGATGCC CAACCAGGCG CAGATGCGGA TCCTGAAAGA GACGGAGCTG
AGGAAGGTGA AGGTGCTTGG ATCTGGCGCT TTTGGCACAG TCTACAAGGG CATCTGGATC
CCTGATGGGG AGAATGTGAA AATTCCAGTG GCCATCAAAG TGTTGAGGGA AAACACATCC
CCCAAAGCCA ACAAAGAAAT CTTAGACGAA GCATACGTGA TGGCTGGTGT GGGCTCCCCA
TATGTCTCCC GCCTTCTGGG CATCTGCCTG ACATCCACGG TGCAGCTGGT GACACAGCTT
ATGCCCTATG GCTGCCTCTT AGACCATGTC CGGGAAAACC GCGGACGCCT GGGCTCCCAG
GACCTGCTGA ACTGGTGTAT GCAGATTGCC AAGGGGATGA GCTACCTGGA GGATGTGCGG
CTCGTACACA GGGACTTGGC CGCTCGGAAC GTGCTGGTCA AGAGTCCCAA CCATGTCAAA
ATTACAGACT TCGGGCTGGC TCGGCTGCTG GACATTGACG AGACAGAGTA CCATGCAGAT
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCA TTCTCCGCCG GCGGTTCACC
CACCAGAGTG ATGTGTGGAG TTATGGTGTG ACTGTGTGGG AGCTGATGAC TTTTGGGGCC
AAACCTTACG ATGGGATCCC AGCCCGGGAG ATCCCTGACC TGCTGGAAAA GGGGGAGCGG
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA ATGTTGGATG
ATTGACTCTG AATGTCGGCC AAGATTCCGG GAGTTGGTGT CTGAATTCTC CCGCATGGCC
AGGGACCCCC AGCGCTTTGT GGTCATCCAG AATGAGGACT TGGGCCCAGC CAGTCCCTTG
GACAGCACCT TCTACCGCTC ACTGCTGGAG GACGATGACA TGGGGGACCT GGTGGATGCT
GAGGAGTATC TGGTACCCCA GCAGGGCTTC TTCTGTCCAG ACCCTGCCCC GGGCGCTGGG
GGCATGGTCC ACCACAGGCA CCGCAGCTCA TCTACCAGGA GTGGCGGTGG GGACCTGACA
CTAGGGCTGG AGCCCTCTGA AGAGGAGGCC CCCAGGTCTC CACTGGCACC CTCCGAAGGG
GCTGGCTCCG ATGTATTTGA TGGTGACCTG GGAATGGGGG CAGCCAAGGG GCTGCAAAGC
CTCCCCACAC ATGACCCCAG CCCTCTACAG CGGTACAGTG AGGACCCCAC AGTACCCCTG
CCCTCTGAGA CTGATGGCTA CGTTGCCCCC CTGACCTGCA GCCCCCAGCC TGAATATGTG
AACCAGCCAG ATGTTCGGCC CCAGCCCCCT TCGCCCCGAG AGGGCCCTCT GCCTGCTGCC
CGACCTGCTG GTGCCACTCT GGAAAGGCCC AAGACTCTCT CCCCAGGGAA GAATGGGGTC
GTCAAAGACG TTTTTGCCTT TGGGGGTGCC GTGGAGAACC CCGAGTACTT GACACCCCAG
GGAGGAGCTG CCCCTCAGCC CCACCCTCCT CCTGCCTTCA GCCCAGCCTT CGACAACCTC
TATTACTGGG ACCAGGACCC ACCAGAGCGG GGGGCTCCAC CCAGCACCTT CAAAGGGACA
CCTACGGCAG AGAACCCAGA GTACCTGGGT CTGGACGTGC CAGTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_004439.2
CDS262..4029
Misc Feature(1)236..256(+)
Misc Feature(2)415..780(+)
Misc Feature(3)826..1290(+)
Misc Feature(4)964..1101(+)
Misc Feature(5)1357..1719(+)
Misc Feature(6)1789..>1893(+)
Misc Feature(7)1792..2190(+)
Misc Feature(8)1945..2082(+)
Misc Feature(9)2182..2313(+)
Misc Feature(10)2188..2262(+)
Misc Feature(11)2191..2274(+)
Misc Feature(12)2218..2286(+)
Misc Feature(13)2287..2328(+)
Misc Feature(14)2287..2328(+)
Misc Feature(15)2395..3231(+)
Misc Feature(16)2419..3189(+)
Misc Feature(17)2437..2952(+)
Misc Feature(18)2437..2850(+)
Misc Feature(19)2464..2466(+)
Misc Feature(20)2845..2922(+)
Misc Feature(21)2890..2892(+)
Misc Feature(22)2911..2952(+)
Misc Feature(23)3028..3030(+)
Misc Feature(24)3274..3276(+)
Misc Feature(25)3328..3330(+)
Misc Feature(26)3421..3423(+)
Misc Feature(27)3580..3582(+)
Misc Feature(28)3676..3678(+)
Misc Feature(29)3676..3678(+)
Misc Feature(30)3712..3714(+)
Misc Feature(31)3844..3852(+)
Misc Feature(32)3847..3849(+)
Misc Feature(33)3847..3849(+)
Misc Feature(34)3922..3924(+)
Misc Feature(35)3925..3927(+)
Misc Feature(36)4003..4005(+)
Misc Feature(37)4003..4005(+)
Misc Feature(38)4003..4005(+)
Misc Feature(39)4003..4005(+)
Misc Feature(40)4003..4005(+)
Exon (1)1..334
Gene:ERBB2
Gene Synonym:
Exon (2)335..486
Gene:ERBB2
Gene Synonym:
Exon (3)487..700
Gene:ERBB2
Gene Synonym:
Exon (4)701..835
Gene:ERBB2
Gene Synonym:
Exon (5)836..904
Gene:ERBB2
Gene Synonym:
Exon (6)905..1020
Gene:ERBB2
Gene Synonym:
Exon (7)1021..1162
Gene:ERBB2
Gene Synonym:
Exon (8)1163..1282
Gene:ERBB2
Gene Synonym:
Exon (9)1283..1409
Gene:ERBB2
Gene Synonym:
Exon (10)1410..1483
Gene:ERBB2
Gene Synonym:
Exon (11)1484..1574
Gene:ERBB2
Gene Synonym:
Exon (12)1575..1774
Gene:ERBB2
Gene Synonym:
Exon (13)1775..1907
Gene:ERBB2
Gene Synonym:
Exon (14)1908..1998
Gene:ERBB2
Gene Synonym:
Exon (15)1999..2159
Gene:ERBB2
Gene Synonym:
Exon (16)2160..2207
Gene:ERBB2
Gene Synonym:
Exon (17)2208..2346
Gene:ERBB2
Gene Synonym:
Exon (18)2347..2469
Gene:ERBB2
Gene Synonym:
Exon (19)2470..2568
Gene:ERBB2
Gene Synonym:
Exon (20)2569..2754
Gene:ERBB2
Gene Synonym:
Exon (21)2755..2910
Gene:ERBB2
Gene Synonym:
Exon (22)2911..2986
Gene:ERBB2
Gene Synonym:
Exon (23)2987..3133
Gene:ERBB2
Gene Synonym:
Exon (24)3134..3231
Gene:ERBB2
Gene Synonym:
Exon (25)3232..3420
Gene:ERBB2
Gene Synonym:
Exon (26)3421..3673
Gene:ERBB2
Gene Synonym:
Exon (27)3674..4647
Gene:ERBB2
Gene Synonym:
Translation
Position Chain Variation Link
3 3 c, t dbSNP:528194999
17 17 a, c dbSNP:761043239
26 26 a, g dbSNP:540373743
36 36 a, g dbSNP:538872680
49 49 c, t dbSNP:764665578
95 95 c, t dbSNP:528930915
96 96 c, t dbSNP:550828061
102 102 c, t dbSNP:375591649
103 103 a, g dbSNP:569077403
189 189 a, g dbSNP:533116130
211 211 c, t dbSNP:762295163
216 216 a, t dbSNP:551298195
221 221 c, g dbSNP:779641368
225 225 c, t dbSNP:748926804
231 231 c, g dbSNP:768240855
234 234 c, t dbSNP:566910530
250 250 g, t dbSNP:773855470
258 258 c, g dbSNP:572294002
304 304 c, t dbSNP:193171026
312 312 a, c dbSNP:567022720
330 330 c, t dbSNP:773744480
335 335 c, t dbSNP:755921683
340 340 a, c dbSNP:779913120
342 342 c, t dbSNP:377542789
343 343 a, g dbSNP:564064363
345 345 c, g dbSNP:528118039
349 349 g, t dbSNP:778487069
354 354 g, t dbSNP:546886845
358 358 c, t dbSNP:771576995
360 360 a, g dbSNP:4252610
361 361 c, t dbSNP:149937802
363 363 a, g dbSNP:369293607
365 365 c, t dbSNP:777171280
366 366 c, t dbSNP:759935065
370 370 c, g dbSNP:765607521
378 378 c, t dbSNP:775826753
379 379 a, g dbSNP:763193414
394 394 a, g dbSNP:587778266
398 398 c, t dbSNP:764222200
401 401 a, g dbSNP:144019910
431 431 a, g dbSNP:140441229
442 442 c, g dbSNP:766186178
449 449 c, t dbSNP:753655456
453 453 c, t dbSNP:754742686
460 460 a, g dbSNP:778575008
461 461 c, t dbSNP:752339377
464 464 a, g dbSNP:757899978
467 467 c, g dbSNP:777347427
471 471 -, c dbSNP:754691039
486 486 -, g dbSNP:780661804
497 497 a, c dbSNP:61737968
510 510 c, t dbSNP:191376350
511 511 a, g dbSNP:376524324
517 517 a, g dbSNP:759478535
519 519 c, t dbSNP:147785188
520 520 a, g dbSNP:775382058
525 525 a, c dbSNP:762638680
530 530 a, c dbSNP:763850846
534 534 a, g dbSNP:369499945
543 543 a, c dbSNP:756850857
545 545 c, t dbSNP:767151455
559 559 c, t dbSNP:749886389
560 560 a, g dbSNP:756720659
563 563 c, t dbSNP:539140755
573 573 c, t dbSNP:576471733
590 590 a, g dbSNP:749711404
594 594 c, t dbSNP:755265117
601 601 c, t dbSNP:372811772
605 605 c, t dbSNP:748301823
606 606 c, t dbSNP:200102353
612 612 a, g dbSNP:370676964
618 618 c, t dbSNP:747047846
622 622 a, g dbSNP:769775277
625 625 c, g dbSNP:141135746
626 626 c, t dbSNP:370959592
627 627 a, g dbSNP:762875937
628 628 c, t dbSNP:763786330
642 642 c, g dbSNP:4252613
643 643 c, g dbSNP:761564667
644 644 c, g dbSNP:373824622
645 645 c, g, t dbSNP:749976401
646 646 g, t dbSNP:766949725
661 661 c, t dbSNP:754295165
667 667 a, g dbSNP:755427616
671 671 c, t dbSNP:200208742
673 673 c, t dbSNP:779156384
674 674 a, g dbSNP:748476466
678 678 g, t dbSNP:758646541
689 689 a, g dbSNP:185670819
694 694 c, t dbSNP:527779103
713 713 g, t dbSNP:200963868
716 716 c, g dbSNP:151122410
717 717 a, g dbSNP:758734557
718 718 c, g dbSNP:778041266
720 720 c, t dbSNP:751770717
723 723 c, g dbSNP:757446217
730 730 c, t dbSNP:781137961
731 731 a, g dbSNP:745921471
735 735 c, t dbSNP:768502081
736 736 a, c dbSNP:778888794
742 742 c, g dbSNP:774604250
747 747 c, t dbSNP:775319988
752 752 a, g dbSNP:747995543
754 754 c, g dbSNP:771986239
759 759 a, g dbSNP:370810322
783 783 c, t dbSNP:141086703
789 789 c, t dbSNP:56114611
791 791 a, g dbSNP:776032539
798 798 a, g dbSNP:146844678
823 823 a, c, t dbSNP:765706190
824 824 a, g dbSNP:763371007
829 829 c, t dbSNP:753419830
830 830 a, g dbSNP:531563820
840 840 c, g, t dbSNP:769335702
841 841 c, t dbSNP:763458661
842 842 c, t dbSNP:764545872
851 851 c, t dbSNP:113619125
852 852 a, g dbSNP:762217415
855 855 a, g dbSNP:767673890
863 863 g, t dbSNP:750651941
891 891 a, g dbSNP:756204333
894 894 c, t dbSNP:766580117
902 902 g, t dbSNP:753902254
904 904 c, t dbSNP:577260523
908 908 c, t dbSNP:770976272
909 909 a, g dbSNP:779058669
910 910 c, t dbSNP:768151310
911 911 a, g dbSNP:779346332
924 924 c, t dbSNP:748701236
925 925 a, g dbSNP:772393268
936 936 c, g dbSNP:140636713
937 937 c, t dbSNP:760895559
938 938 a, g dbSNP:745625627
949 949 c, t dbSNP:776960538
955 955 a, c dbSNP:759753872
978 978 a, g dbSNP:765424712
982 982 a, g dbSNP:752656997
988 988 a, g dbSNP:533090552
989 989 g, t dbSNP:767309845
995 995 c, t dbSNP:376183465
996 996 a, g dbSNP:755873891
1009 1009 c, t dbSNP:779750598
1028 1028 c, t dbSNP:777081311
1029 1029 c, t dbSNP:759845382
1037 1037 a, g dbSNP:769870618
1038 1038 c, t dbSNP:775666242
1039 1039 c, t dbSNP:762919589
1046 1046 a, g dbSNP:548076348
1048 1048 a, t dbSNP:750324803
1050 1050 c, t dbSNP:760523023
1053 1053 c, t dbSNP:368210132
1056 1056 a, g dbSNP:530186646
1060 1060 c, t dbSNP:773759626
1069 1069 g, t dbSNP:200382130
1070 1070 c, t dbSNP:754656388
1071 1071 c, t dbSNP:764747320
1079 1079 c, t dbSNP:752295912
1094 1094 a, c dbSNP:757811990
1105 1105 a, c dbSNP:778408285
1116 1116 c, t dbSNP:747503021
1117 1117 a, g dbSNP:149210045
1124 1124 a, g dbSNP:760205387
1129 1129 a, g dbSNP:746190897
1134 1134 c, t dbSNP:770104901
1135 1135 a, g dbSNP:775544453
1137 1137 c, t dbSNP:749453104
1166 1166 a, t dbSNP:768855063
1170 1170 c, t dbSNP:774443757
1173 1173 c, t dbSNP:748176467
1182 1182 c, t dbSNP:770903497
1183 1183 a, g dbSNP:776515406
1188 1188 a, t dbSNP:145697136
1200 1200 c, t dbSNP:138280629
1201 1201 a, g dbSNP:775294491
1213 1213 c, t dbSNP:762547363
1227 1227 g, t dbSNP:546000185
1244 1244 a, c, t dbSNP:763793826
1249 1249 c, t dbSNP:761376658
1250 1250 a, g dbSNP:768206712
1253 1253 a, g dbSNP:564382616
1257 1257 a, g dbSNP:756588194
1260 1260 a, g dbSNP:780283935
1262 1262 -, g dbSNP:769703068
1263 1263 c, t dbSNP:754188777
1280 1280 a, g dbSNP:532077147
1287 1287 c, t dbSNP:778968985
1289 1289 a, g dbSNP:747993530
1291 1291 c, g dbSNP:758204762
1296 1296 a, g dbSNP:777348537
1301 1301 a, t dbSNP:746686273
1309 1309 c, t dbSNP:770421665
1311 1311 a, c, g dbSNP:559242250
1312 1312 a, c dbSNP:770327076
1313 1313 a, g dbSNP:775972596
1316 1316 a, g dbSNP:763367024
1318 1318 g, t dbSNP:769082334
1326 1326 a, g dbSNP:190567339
1340 1340 a, t dbSNP:373474372
1341 1341 c, t dbSNP:762129422
1357 1357 c, g dbSNP:767588058
1359 1359 c, g dbSNP:750577335
1368 1368 a, g dbSNP:760803727
1374 1374 c, t dbSNP:149567593
1384 1384 a, g dbSNP:752664566
1394 1394 c, t dbSNP:758210687
1395 1395 a, g dbSNP:143225142
1399 1399 a, g dbSNP:148068883
1409 1409 a, g dbSNP:751270411
1411 1411 a, g dbSNP:753902259
1413 1413 c, t dbSNP:199514902
1418 1418 a, c, g dbSNP:141116145
1419 1419 c, t dbSNP:756999086
1423 1423 a, c dbSNP:780881510
1424 1424 a, g dbSNP:750090147
1429 1429 a, g dbSNP:755701444
1430 1430 c, t dbSNP:587778264
1431 1431 c, t dbSNP:544011927
1433 1433 c, t dbSNP:748700504
1434 1434 a, c, g dbSNP:769257889
1437 1437 c, g dbSNP:562384569
1440 1440 a, g dbSNP:147204600
1442 1442 c, t dbSNP:772548631
1454 1454 a, g dbSNP:773649491
1456 1456 a, g dbSNP:747239268
1468 1468 a, c, t dbSNP:377649991
1470 1470 a, g dbSNP:776871033
1492 1492 g, t dbSNP:587778265
1495 1495 a, g dbSNP:758908894
1503 1503 a, c, g dbSNP:373728539
1508 1508 c, t dbSNP:747327229
1509 1509 a, g dbSNP:140507994
1511 1511 a, c dbSNP:776714622
1517 1517 g, t dbSNP:746020984
1525 1525 a, c dbSNP:769778398
1528 1528 a, g dbSNP:199668084
1530 1530 c, t dbSNP:35757908
1531 1531 a, g dbSNP:142783371
1549 1549 a, g dbSNP:767398280
1555 1555 c, t dbSNP:367606199
1562 1562 a, g dbSNP:147382623
1570 1570 c, t dbSNP:766083302
1578 1578 c, t dbSNP:750754275
1579 1579 a, g dbSNP:756345214
1581 1581 a, c dbSNP:780294548
1586 1586 c, t dbSNP:749440298
1587 1587 g, t dbSNP:4252632
1593 1593 a, c dbSNP:778904008
1596 1596 a, g dbSNP:746949970
1609 1609 a, g dbSNP:770857517
1617 1617 g, t dbSNP:4252633
1618 1618 c, g dbSNP:759352819
1627 1627 c, t dbSNP:200497646
1632 1632 a, g dbSNP:2230698
1633 1633 c, t dbSNP:368989970
1646 1646 a, g, t dbSNP:373192991
1658 1658 c, t dbSNP:751074421
1670 1670 a, g dbSNP:201097345
1676 1676 c, t dbSNP:768049972
1677 1677 c, t dbSNP:61737967
1678 1678 c, g dbSNP:756500045
1687 1687 g, t dbSNP:780201941
1689 1689 c, t dbSNP:532023577
1690 1690 a, g dbSNP:755121772
1697 1697 c, t dbSNP:201021373
1701 1701 a, g dbSNP:748176472
1703 1703 c, t dbSNP:370565888
1704 1704 c, g, t dbSNP:55984118
1708 1708 a, g dbSNP:571837012
1719 1719 c, t dbSNP:539260608
1720 1720 c, t dbSNP:375382055
1721 1721 a, c, g dbSNP:371450390
1725 1725 a, c dbSNP:768374532
1727 1727 c, t dbSNP:142456637
1728 1728 a, g dbSNP:147076339
1732 1732 c, g, t dbSNP:140670446
1748 1748 c, t dbSNP:767978749
1750 1750 a, g dbSNP:145762641
1756 1756 a, c, g, t dbSNP:199530208
1757 1757 a, g, t dbSNP:182572604
1767 1767 c, t dbSNP:752759368
1768 1768 a, g dbSNP:758497995
1791 1791 c, g dbSNP:765510261
1806 1806 c, t dbSNP:368632077
1807 1807 a, g dbSNP:371623072
1811 1811 a, g dbSNP:759579850
1815 1815 a, g dbSNP:199657476
1826 1826 a, g dbSNP:561322621
1828 1828 c, t dbSNP:202202058
1830 1830 a, g dbSNP:55928971
1839 1839 c, g, t dbSNP:754811013
1846 1846 a, g dbSNP:747838206
1850 1850 a, g dbSNP:771580372
1852 1852 c, t dbSNP:140711914
1855 1855 a, c dbSNP:777363214
1864 1864 c, t dbSNP:746476368
1868 1868 a, g dbSNP:140980495
1875 1875 g, t dbSNP:777116958
1881 1881 c, t dbSNP:371585581
1885 1885 g, t dbSNP:770157051
1893 1893 c, t dbSNP:775678910
1895 1895 a, g dbSNP:150203173
1903 1903 a, c, t dbSNP:565582943
1906 1906 g, t dbSNP:532713027
1908 1908 g, t dbSNP:775974838
1911 1911 c, t dbSNP:763197991
1920 1920 a, g dbSNP:768992351
1923 1923 c, t dbSNP:774426489
1926 1926 a, g dbSNP:762073749
1938 1938 c, g, t dbSNP:767713671
1942 1942 c, t dbSNP:369690252
1946 1946 c, t dbSNP:201470725
1947 1947 a, c, g dbSNP:4252635
1967 1967 c, t dbSNP:763863372
1974 1974 c, t dbSNP:149337787
1976 1976 g, t dbSNP:756836001
1986 1986 a, c, t dbSNP:780703792
1991 1991 g, t dbSNP:778479390
1997 1997 c, t dbSNP:756686824
2007 2007 c, t dbSNP:138893464
2033 2033 a, t dbSNP:767216520
2039 2039 c, t dbSNP:750092447
2042 2042 a, c dbSNP:760310908
2043 2043 a, c dbSNP:765842816
2049 2049 c, t dbSNP:753344199
2050 2050 a, g dbSNP:755483857
2054 2054 a, c, g dbSNP:145409713
2056 2056 c, t dbSNP:369903296
2057 2057 a, g dbSNP:758820578
2058 2058 c, g dbSNP:778223078
2067 2067 c, t dbSNP:747200104
2068 2068 a, g dbSNP:771145294
2069 2069 a, g dbSNP:781179380
2076 2076 a, g dbSNP:538900246
2085 2085 c, t dbSNP:768648444
2089 2089 c, t dbSNP:774261411
2092 2092 a, g dbSNP:377370642
2106 2106 a, g dbSNP:771862037
2118 2118 a, g dbSNP:142816898
2124 2124 c, t dbSNP:760271180
2125 2125 a, g dbSNP:766029214
2127 2127 a, g dbSNP:753325392
2135 2135 c, t dbSNP:759078493
2136 2136 c, t dbSNP:765900638
2146 2146 a, g dbSNP:753267835
2147 2147 a, c dbSNP:758907167
2155 2155 c, t dbSNP:778312796
2159 2159 c, t dbSNP:199726056
2187 2187 c, t dbSNP:541854282
2189 2189 c, g dbSNP:367599823
2190 2190 c, g, t dbSNP:56110910
2191 2191 a, g dbSNP:750665964
2193 2193 c, t dbSNP:141678288
2194 2194 a, g dbSNP:370514427
2201 2201 a, c, g dbSNP:201784472
2203 2203 a, g dbSNP:777759226
2210 2210 c, t dbSNP:778798172
2211 2211 c, t dbSNP:746968535
2212 2212 c, t dbSNP:757101082
2220 2220 c, t dbSNP:374222106
2221 2221 a, c, g dbSNP:1801201
2223 2223 c, t dbSNP:779841027
2224 2224 a, g, t dbSNP:1136201
2226 2226 c, t dbSNP:768217764
2229 2229 g, t dbSNP:577329788
2242 2242 a, g dbSNP:762407538
2253 2253 c, g dbSNP:772440208
2262 2262 a, g dbSNP:773610266
2263 2263 c, g dbSNP:372616729
2265 2265 a, c, g dbSNP:199841166
2296 2296 c, g dbSNP:759608479
2309 2309 c, g dbSNP:765387989
2314 2314 c, t dbSNP:752669313
2343 2343 a, g dbSNP:757266514
2367 2367 c, t dbSNP:762937851
2369 2369 g, t dbSNP:34602395
2370 2370 c, t dbSNP:764211319
2391 2391 a, g dbSNP:750389304
2396 2396 g, t dbSNP:756073738
2399 2399 a, g dbSNP:779034594
2409 2409 a, g dbSNP:146883671
2415 2415 a, g dbSNP:753552215
2419 2419 c, t dbSNP:374098949
2439 2439 c, t dbSNP:778422158
2457 2457 c, t dbSNP:377617979
2464 2464 c, t dbSNP:757863234
2497 2497 a, g dbSNP:781547782
2501 2501 a, c dbSNP:746301859
2524 2524 cc, tt dbSNP:121913469
2525 2525 c, t dbSNP:121913470
2541 2541 c, t dbSNP:779727777
2544 2544 c, t dbSNP:775883027
2553 2553 c, t dbSNP:139745101
2562 2562 a, c dbSNP:768974971
2564 2564 c, t dbSNP:56366519
2566 2566 c, g dbSNP:121913468
2568 2568 c, t dbSNP:774610157
2577 2577 c, t dbSNP:748318804
2578 2578 a, g dbSNP:772054394
2581 2581 -, a dbSNP:397516978
2583 2583 -, gcatacgtgatg dbSNP:397516975
2583 2583 g, t dbSNP:773305795
2585 2585 -, atacgtgatggc, ctccgtgatggc dbSNP:397516976
2586 2586 -, tacgtgatggct, tccgtgatggct dbSNP:397516977
2587 2587 -, tct, tgt, ttt dbSNP:397516979
2587 2587 a, g dbSNP:28933369
2587 2587 g, ttat dbSNP:397516980
2588 2588 a, c, g, t dbSNP:144434331
2590 2590 g, t dbSNP:121913471
2592 2592 -, g dbSNP:748202083
2597 2597 -, tgtgggctc dbSNP:587776805
2597 2597 c, t dbSNP:775190312
2598 2598 c, t dbSNP:762733948
2600 2600 -, gggctcccc dbSNP:397516981
2601 2601 -, ggctcccca dbSNP:397516982
2610 2610 c, t dbSNP:763795273
2612 2612 a, g dbSNP:751226373
2629 2629 c, t dbSNP:761415465
2639 2639 c, t dbSNP:766958268
2640 2640 a, g dbSNP:186232310
2646 2646 a, g dbSNP:756617192
2652 2652 a, g dbSNP:368499773
2661 2661 c, t dbSNP:754308267
2669 2669 a, g dbSNP:755402782
2685 2685 a, c dbSNP:146603731
2692 2692 c, t dbSNP:748416534
2693 2693 a, g dbSNP:775752713
2701 2701 c, t dbSNP:587778267
2703 2703 c, t dbSNP:553270501
2704 2704 a, g dbSNP:368094521
2707 2707 c, t dbSNP:542027040
2708 2708 a, g dbSNP:775394020
2709 2709 a, c dbSNP:762819802
2712 2712 a, g, t dbSNP:768470177
2730 2730 a, g dbSNP:557172740
2745 2745 c, g dbSNP:767164590
2767 2767 c, t dbSNP:104886008
2769 2769 a, g dbSNP:149176913
2779 2779 c, t dbSNP:369828131
2780 2780 a, g dbSNP:747967722
2781 2781 a, g dbSNP:104886011
2784 2784 c, t dbSNP:373165016
2796 2796 c, t dbSNP:137852788
2797 2797 c, t dbSNP:370816244
2802 2802 c, t dbSNP:140231769
2808 2808 a, g dbSNP:766022187
2811 2811 c, t dbSNP:776236294
2812 2812 a, g dbSNP:375043510
2824 2824 a, g dbSNP:765811300
2829 2829 c, t dbSNP:104886009
2831 2831 a, g dbSNP:28933370
2835 2835 c, t dbSNP:377653295
2847 2847 a, t dbSNP:758778485
2850 2850 c, t dbSNP:764308274
2853 2853 c, t dbSNP:151263346
2866 2866 c, t dbSNP:104886010
2871 2871 a, g dbSNP:757372006
2875 2875 a, g, t dbSNP:371081280
2880 2880 c, t dbSNP:540921632
2881 2881 a, g dbSNP:375637720
2899 2899 c, g dbSNP:747974836
2916 2916 c, t dbSNP:756196886
2917 2917 a, g dbSNP:780037152
2931 2931 a, g dbSNP:140453509
2947 2947 c, t dbSNP:758222990
2948 2948 a, g dbSNP:777677468
2949 2949 c, t dbSNP:369203202
2950 2950 c, t dbSNP:375135008
2955 2955 a, g dbSNP:199638358
2961 2961 c, g dbSNP:370134709
2966 2966 a, c dbSNP:188440186
2967 2967 c, g dbSNP:193920750
2976 2976 a, g dbSNP:769432866
2988 2988 g, t dbSNP:760843554
2991 2991 a, g dbSNP:766499882
3001 3001 a, g dbSNP:28933368
3026 3026 c, g dbSNP:753844448
3030 3030 c, t dbSNP:147028804
3031 3031 a, g dbSNP:777570707
3036 3036 c, g dbSNP:575812477
3045 3045 c, t dbSNP:757132983
3046 3046 c, t dbSNP:781070018
3047 3047 a, g dbSNP:201399875
3051 3051 g, t dbSNP:138957632
3057 3057 c, t dbSNP:779653888
3082 3082 c, t dbSNP:748743338
3085 3085 c, g, t dbSNP:769262054
3087 3087 c, t dbSNP:141423785
3094 3094 c, t dbSNP:772452342
3096 3096 -, t dbSNP:774137752
3096 3096 a, c, g dbSNP:543123530
3112 3112 a, g dbSNP:766483219
3119 3119 -, tgatcatgg dbSNP:745798193
3135 3135 c, t dbSNP:775663547
3143 3143 c, t dbSNP:761891977
3144 3144 g, t dbSNP:767556375
3146 3146 a, g dbSNP:750299289
3151 3151 c, g dbSNP:767813285
3157 3157 c, t dbSNP:753151506
3158 3158 a, g dbSNP:755874371
3169 3169 c, t dbSNP:766129765
3170 3170 a, g dbSNP:753460336
3175 3175 c, t dbSNP:201193677
3176 3176 c, t dbSNP:778440239
3183 3183 c, t dbSNP:747628943
3193 3193 c, t dbSNP:758973569
3194 3194 a, g dbSNP:778243900
3196 3196 a, g dbSNP:747461130
3214 3214 c, t dbSNP:771206209
3226 3226 a, c, g dbSNP:202110098
3242 3242 c, t dbSNP:774636044
3251 3251 a, c dbSNP:752037952
3252 3252 c, t dbSNP:757734622
3260 3260 c, t dbSNP:781460225
3262 3262 g, t dbSNP:746213900
3267 3267 c, t dbSNP:770197622
3277 3277 c, t dbSNP:780434636
3278 3278 a, g dbSNP:749454186
3285 3285 a, g dbSNP:765296069
3294 3294 c, t dbSNP:373188896
3295 3295 a, g dbSNP:774520188
3301 3301 a, g dbSNP:760573708
3305 3305 a, g dbSNP:140272156
3320 3320 c, g dbSNP:776359403
3331 3331 c, t dbSNP:4252654
3338 3338 a, c dbSNP:192441765
3339 3339 c, t dbSNP:4252655
3341 3341 -, agcaggg dbSNP:760152942
3350 3350 g, t dbSNP:762553217
3368 3368 c, t dbSNP:763617317
3369 3369 c, t dbSNP:545969208
3371 3371 c, t dbSNP:201905649
3372 3372 a, g dbSNP:781713745
3375 3375 c, t dbSNP:766276087
3376 3376 a, g dbSNP:566053951
3396 3396 c, g dbSNP:756551038
3403 3403 c, t dbSNP:377602610
3404 3404 a, g dbSNP:749539903
3407 3407 a, g dbSNP:104886025
3410 3410 c, t dbSNP:199905364
3411 3411 a, t dbSNP:748251749
3413 3413 a, c dbSNP:139630504
3417 3417 c, g dbSNP:561720540
3418 3418 a, g dbSNP:370561486
3426 3426 -, gggggg dbSNP:145292805
3427 3427 a, g dbSNP:574436396
3429 3429 c, g, t dbSNP:774056001
3434 3434 a, c dbSNP:201374810
3436 3436 c, t dbSNP:369832936
3437 3437 c, t dbSNP:772570852
3443 3443 c, t dbSNP:141142822
3451 3451 a, g dbSNP:376450229
3463 3463 c, g dbSNP:754310116
3479 3479 c, g dbSNP:202149348
3490 3490 c, g dbSNP:765456216
3494 3494 c, t dbSNP:748800582
3495 3495 c, t dbSNP:538414026
3502 3502 c, g dbSNP:772604432
3510 3510 a, c, t dbSNP:376673270
3511 3511 a, g, t dbSNP:200796676
3513 3513 a, t dbSNP:779955263
3524 3524 a, g dbSNP:749154778
3529 3529 c, g, t dbSNP:768526064
3537 3537 a, g dbSNP:747883291
3539 3539 a, g dbSNP:771588633
3549 3549 c, g dbSNP:373724781
3550 3550 a, g dbSNP:760245870
3555 3555 a, g dbSNP:770506053
3566 3566 c, t dbSNP:200455249
3569 3569 c, t dbSNP:759923732
3574 3574 a, g dbSNP:111611886
3576 3576 c, t dbSNP:765660593
3592 3592 c, t dbSNP:143958183
3593 3593 a, g dbSNP:763276772
3598 3598 a, g dbSNP:764220279
3612 3612 a, g dbSNP:368135224
3621 3621 a, g dbSNP:746042501
3628 3628 a, c, g dbSNP:757332075
3636 3636 a, c, t dbSNP:148211805
3642 3642 c, t dbSNP:545806496
3643 3643 a, g dbSNP:747888253
3646 3646 -, c dbSNP:766671083
3646 3646 c, g dbSNP:556924554
3651 3651 c, g dbSNP:771812007
3664 3664 c, t dbSNP:150165942
3667 3667 c, t dbSNP:746595697
3678 3678 c, t dbSNP:770391447
3679 3679 a, g dbSNP:775877222
3684 3684 a, c dbSNP:146177313
3688 3688 a, c dbSNP:587778268
3689 3689 c, t dbSNP:587778269
3690 3690 a, g dbSNP:769929665
3691 3691 c, g dbSNP:138611862
3697 3697 c, t dbSNP:762062043
3698 3698 a, g dbSNP:767717383
3699 3699 a, g dbSNP:370079170
3702 3702 a, c, t dbSNP:112561362
3709 3709 c, g dbSNP:562773948
3711 3711 c, t dbSNP:760679991
3714 3714 a, g dbSNP:144501267
3717 3717 c, t dbSNP:551805660
3719 3719 a, g dbSNP:758365405
3720 3720 a, c dbSNP:567023682
3724 3724 a, g, t dbSNP:751372943
3731 3731 g, t dbSNP:757037466
3735 3735 g, t dbSNP:373365159
3743 3743 a, g dbSNP:150680317
3744 3744 a, g dbSNP:755586442
3745 3745 c, t dbSNP:201482456
3762 3762 a, g dbSNP:749807221
3768 3768 a, g dbSNP:769120310
3769 3769 c, g dbSNP:1058808
3780 3780 c, t dbSNP:748495392
3790 3790 a, t dbSNP:772360944
3792 3792 a, g, t dbSNP:4252656
3799 3799 -, gtc dbSNP:751889439
3801 3801 c, t dbSNP:759480536
3802 3802 a, g dbSNP:776754071
3805 3805 a, c dbSNP:763027953
3806 3806 a, g dbSNP:764123297
3810 3810 c, t dbSNP:767230649
3811 3811 a, g dbSNP:761715861
3831 3831 c, t dbSNP:149815705
3834 3834 a, g dbSNP:750063274
3835 3835 g, t dbSNP:182815010
3843 3843 c, t dbSNP:755767616
3856 3856 a, c dbSNP:779469693
3871 3871 a, g dbSNP:753337412
3872 3872 c, g dbSNP:373605104
3873 3873 c, t dbSNP:755536204
3874 3874 c, t dbSNP:201353217
3881 3881 c, t dbSNP:145772320
3891 3891 c, t dbSNP:141627242
3908 3908 a, c dbSNP:55943169
3910 3910 c, t dbSNP:747245215
3912 3912 c, t dbSNP:188050006
3923 3923 a, g dbSNP:568793816
3930 3930 -, ggacca dbSNP:755472707
3937 3937 a, g dbSNP:539683889
3949 3949 -, g dbSNP:768092215
3949 3949 c, t dbSNP:769940977
3950 3950 a, c, g, t dbSNP:372043866
3966 3966 c, t dbSNP:4252657
3967 3967 a, t dbSNP:750197828
3977 3977 a, g dbSNP:760307857
3979 3979 a, c dbSNP:766037507
3982 3982 c, t dbSNP:753431083
3983 3983 c, g dbSNP:141494080
3986 3986 c, t dbSNP:778352367
3987 3987 a, g dbSNP:753222413
3991 3991 a, g dbSNP:144533600
3998 3998 -, a dbSNP:752875197
3998 3998 c, t dbSNP:375408471
4002 4002 a, g dbSNP:368770921
4004 4004 a, g dbSNP:771116500
4005 4005 c, t dbSNP:781493914
4014 4014 a, g dbSNP:746024186
4015 4015 a, g dbSNP:184203026
4017 4017 c, t dbSNP:775687641
4018 4018 a, g dbSNP:36085723
4023 4023 a, c dbSNP:761879528
4024 4024 g, t dbSNP:755744500
4025 4025 c, t dbSNP:772934121
4034 4034 a, g, t dbSNP:2230700
4035 4035 a, c, g dbSNP:376055107
4036 4036 a, c, g dbSNP:759138887
4046 4046 c, t dbSNP:369214536
4047 4047 a, g dbSNP:763698349
4052 4052 a, c dbSNP:764649330
4054 4054 a, c dbSNP:777932453
4061 4061 a, g dbSNP:751957841
4066 4066 c, t dbSNP:772864303
4069 4069 -, ag dbSNP:756233934
4077 4077 c, g dbSNP:562868556
4079 4079 a, g dbSNP:192237900
4085 4085 c, g dbSNP:545634588
4086 4086 c, t dbSNP:560774319
4095 4095 c, t dbSNP:4252658
4103 4103 -, a dbSNP:537313073
4104 4104 -, a dbSNP:4252659
4151 4151 -, g dbSNP:36042695
4156 4156 c, t dbSNP:549594933
4189 4189 -, c dbSNP:35040721
4213 4213 c, g dbSNP:567252769
4225 4225 g, t dbSNP:756776172
4230 4230 a, t dbSNP:189417058
4256 4256 c, g dbSNP:550418471
4264 4264 c, g dbSNP:778498515
4286 4286 c, t dbSNP:139158322
4315 4315 c, t dbSNP:747455080
4350 4350 a, g dbSNP:539073563
4354 4354 c, g dbSNP:755575307
4359 4359 a, c dbSNP:781648400
4372 4372 c, t dbSNP:748570170
4405 4405 c, g dbSNP:762528320
4442 4442 c, g dbSNP:4252660
4465 4465 c, g dbSNP:377267613
4488 4488 a, g dbSNP:770027275
4493 4493 c, g dbSNP:530844735
4507 4507 -, t dbSNP:755980905
4528 4528 g, t dbSNP:749371173
4590 4590 a, g dbSNP:552475695
4620 4620 c, t dbSNP:4252661
4630 4630 c, t dbSNP:774416904

Target ORF information:

RefSeq Version NM_004448
Organism Homo sapiens (human)
Definition Homo sapiens erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_004448

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
ATGGAGCTGG CGGCCTTGTG CCGCTGGGGG CTCCTCCTCG CCCTCTTGCC CCCCGGAGCC 
GCGAGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTGC GGCTCCCTGC CAGTCCCGAG
ACCCACCTGG ACATGCTCCG CCACCTCTAC CAGGGCTGCC AGGTGGTGCA GGGAAACCTG
GAACTCACCT ACCTGCCCAC CAATGCCAGC CTGTCCTTCC TGCAGGATAT CCAGGAGGTG
CAGGGCTACG TGCTCATCGC TCACAACCAA GTGAGGCAGG TCCCACTGCA GAGGCTGCGG
ATTGTGCGAG GCACCCAGCT CTTTGAGGAC AACTATGCCC TGGCCGTGCT AGACAATGGA
GACCCGCTGA ACAATACCAC CCCTGTCACA GGGGCCTCCC CAGGAGGCCT GCGGGAGCTG
CAGCTTCGAA GCCTCACAGA GATCTTGAAA GGAGGGGTCT TGATCCAGCG GAACCCCCAG
CTCTGCTACC AGGACACGAT TTTGTGGAAG GACATCTTCC ACAAGAACAA CCAGCTGGCT
CTCACACTGA TAGACACCAA CCGCTCTCGG GCCTGCCACC CCTGTTCTCC GATGTGTAAG
GGCTCCCGCT GCTGGGGAGA GAGTTCTGAG GATTGTCAGA GCCTGACGCG CACTGTCTGT
GCCGGTGGCT GTGCCCGCTG CAAGGGGCCA CTGCCCACTG ACTGCTGCCA TGAGCAGTGT
GCTGCCGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTCCA CTTCAACCAC
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACAGA CACGTTTGAG
TCCATGCCCA ATCCCGAGGG CCGGTATACA TTCGGCGCCA GCTGTGTGAC TGCCTGTCCC
TACAACTACC TTTCTACGGA CGTGGGATCC TGCACCCTCG TCTGCCCCCT GCACAACCAA
GAGGTGACAG CAGAGGATGG AACACAGCGG TGTGAGAAGT GCAGCAAGCC CTGTGCCCGA
GTGTGCTATG GTCTGGGCAT GGAGCACTTG CGAGAGGTGA GGGCAGTTAC CAGTGCCAAT
ATCCAGGAGT TTGCTGGCTG CAAGAAGATC TTTGGGAGCC TGGCATTTCT GCCGGAGAGC
TTTGATGGGG ACCCAGCCTC CAACACTGCC CCGCTCCAGC CAGAGCAGCT CCAAGTGTTT
GAGACTCTGG AAGAGATCAC AGGTTACCTA TACATCTCAG CATGGCCGGA CAGCCTGCCT
GACCTCAGCG TCTTCCAGAA CCTGCAAGTA ATCCGGGGAC GAATTCTGCA CAATGGCGCC
TACTCGCTGA CCCTGCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC ACTGAGGGAA
CTGGGCAGTG GACTGGCCCT CATCCACCAT AACACCCACC TCTGCTTCGT GCACACGGTG
CCCTGGGACC AGCTCTTTCG GAACCCGCAC CAAGCTCTGC TCCACACTGC CAACCGGCCA
GAGGACGAGT GTGTGGGCGA GGGCCTGGCC TGCCACCAGC TGTGCGCCCG AGGGCACTGC
TGGGGTCCAG GGCCCACCCA GTGTGTCAAC TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC
GTGGAGGAAT GCCGAGTACT GCAGGGGCTC CCCAGGGAGT ATGTGAATGC CAGGCACTGT
TTGCCGTGCC ACCCTGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGTTT TGGACCGGAG
GCTGACCAGT GTGTGGCCTG TGCCCACTAT AAGGACCCTC CCTTCTGCGT GGCCCGCTGC
CCCAGCGGTG TGAAACCTGA CCTCTCCTAC ATGCCCATCT GGAAGTTTCC AGATGAGGAG
GGCGCATGCC AGCCTTGCCC CATCAACTGC ACCCACTCCT GTGTGGACCT GGATGACAAG
GGCTGCCCCG CCGAGCAGAG AGCCAGCCCT CTGACGTCCA TCATCTCTGC GGTGGTTGGC
ATTCTGCTGG TCGTGGTCTT GGGGGTGGTC TTTGGGATCC TCATCAAGCG ACGGCAGCAG
AAGATCCGGA AGTACACGAT GCGGAGACTG CTGCAGGAAA CGGAGCTGGT GGAGCCGCTG
ACACCTAGCG GAGCGATGCC CAACCAGGCG CAGATGCGGA TCCTGAAAGA GACGGAGCTG
AGGAAGGTGA AGGTGCTTGG ATCTGGCGCT TTTGGCACAG TCTACAAGGG CATCTGGATC
CCTGATGGGG AGAATGTGAA AATTCCAGTG GCCATCAAAG TGTTGAGGGA AAACACATCC
CCCAAAGCCA ACAAAGAAAT CTTAGACGAA GCATACGTGA TGGCTGGTGT GGGCTCCCCA
TATGTCTCCC GCCTTCTGGG CATCTGCCTG ACATCCACGG TGCAGCTGGT GACACAGCTT
ATGCCCTATG GCTGCCTCTT AGACCATGTC CGGGAAAACC GCGGACGCCT GGGCTCCCAG
GACCTGCTGA ACTGGTGTAT GCAGATTGCC AAGGGGATGA GCTACCTGGA GGATGTGCGG
CTCGTACACA GGGACTTGGC CGCTCGGAAC GTGCTGGTCA AGAGTCCCAA CCATGTCAAA
ATTACAGACT TCGGGCTGGC TCGGCTGCTG GACATTGACG AGACAGAGTA CCATGCAGAT
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCA TTCTCCGCCG GCGGTTCACC
CACCAGAGTG ATGTGTGGAG TTATGGTGTG ACTGTGTGGG AGCTGATGAC TTTTGGGGCC
AAACCTTACG ATGGGATCCC AGCCCGGGAG ATCCCTGACC TGCTGGAAAA GGGGGAGCGG
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA ATGTTGGATG
ATTGACTCTG AATGTCGGCC AAGATTCCGG GAGTTGGTGT CTGAATTCTC CCGCATGGCC
AGGGACCCCC AGCGCTTTGT GGTCATCCAG AATGAGGACT TGGGCCCAGC CAGTCCCTTG
GACAGCACCT TCTACCGCTC ACTGCTGGAG GACGATGACA TGGGGGACCT GGTGGATGCT
GAGGAGTATC TGGTACCCCA GCAGGGCTTC TTCTGTCCAG ACCCTGCCCC GGGCGCTGGG
GGCATGGTCC ACCACAGGCA CCGCAGCTCA TCTACCAGGA GTGGCGGTGG GGACCTGACA
CTAGGGCTGG AGCCCTCTGA AGAGGAGGCC CCCAGGTCTC CACTGGCACC CTCCGAAGGG
GCTGGCTCCG ATGTATTTGA TGGTGACCTG GGAATGGGGG CAGCCAAGGG GCTGCAAAGC
CTCCCCACAC ATGACCCCAG CCCTCTACAG CGGTACAGTG AGGACCCCAC AGTACCCCTG
CCCTCTGAGA CTGATGGCTA CGTTGCCCCC CTGACCTGCA GCCCCCAGCC TGAATATGTG
AACCAGCCAG ATGTTCGGCC CCAGCCCCCT TCGCCCCGAG AGGGCCCTCT GCCTGCTGCC
CGACCTGCTG GTGCCACTCT GGAAAGGCCC AAGACTCTCT CCCCAGGGAA GAATGGGGTC
GTCAAAGACG TTTTTGCCTT TGGGGGTGCC GTGGAGAACC CCGAGTACTT GACACCCCAG
GGAGGAGCTG CCCCTCAGCC CCACCCTCCT CCTGCCTTCA GCCCAGCCTT CGACAACCTC
TATTACTGGG ACCAGGACCC ACCAGAGCGG GGGGCTCCAC CCAGCACCTT CAAAGGGACA
CCTACGGCAG AGAACCCAGA GTACCTGGGT CTGGACGTGC CAGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27580
Accession Version NM_001005862.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3678bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu27580D_COA.pdf (pdf)
Update Date 15-MAY-2015
Organism Homo sapiens (human)
Product receptor tyrosine-protein kinase erbB-2 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK295195.1, BC110392.1, BC080193.1 and BM678576.1. This sequence is a reference standard in the RefSeqGene project. On Feb 11, 2014 this sequence version replaced gi:54792097. Summary: This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The resulting isoform (b) has a shorter N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
ATGAAGCTGC GGCTCCCTGC CAGTCCCGAG ACCCACCTGG ACATGCTCCG CCACCTCTAC 
CAGGGCTGCC AGGTGGTGCA GGGAAACCTG GAACTCACCT ACCTGCCCAC CAATGCCAGC
CTGTCCTTCC TGCAGGATAT CCAGGAGGTG CAGGGCTACG TGCTCATCGC TCACAACCAA
GTGAGGCAGG TCCCACTGCA GAGGCTGCGG ATTGTGCGAG GCACCCAGCT CTTTGAGGAC
AACTATGCCC TGGCCGTGCT AGACAATGGA GACCCGCTGA ACAATACCAC CCCTGTCACA
GGGGCCTCCC CAGGAGGCCT GCGGGAGCTG CAGCTTCGAA GCCTCACAGA GATCTTGAAA
GGAGGGGTCT TGATCCAGCG GAACCCCCAG CTCTGCTACC AGGACACGAT TTTGTGGAAG
GACATCTTCC ACAAGAACAA CCAGCTGGCT CTCACACTGA TAGACACCAA CCGCTCTCGG
GCCTGCCACC CCTGTTCTCC GATGTGTAAG GGCTCCCGCT GCTGGGGAGA GAGTTCTGAG
GATTGTCAGA GCCTGACGCG CACTGTCTGT GCCGGTGGCT GTGCCCGCTG CAAGGGGCCA
CTGCCCACTG ACTGCTGCCA TGAGCAGTGT GCTGCCGGCT GCACGGGCCC CAAGCACTCT
GACTGCCTGG CCTGCCTCCA CTTCAACCAC AGTGGCATCT GTGAGCTGCA CTGCCCAGCC
CTGGTCACCT ACAACACAGA CACGTTTGAG TCCATGCCCA ATCCCGAGGG CCGGTATACA
TTCGGCGCCA GCTGTGTGAC TGCCTGTCCC TACAACTACC TTTCTACGGA CGTGGGATCC
TGCACCCTCG TCTGCCCCCT GCACAACCAA GAGGTGACAG CAGAGGATGG AACACAGCGG
TGTGAGAAGT GCAGCAAGCC CTGTGCCCGA GTGTGCTATG GTCTGGGCAT GGAGCACTTG
CGAGAGGTGA GGGCAGTTAC CAGTGCCAAT ATCCAGGAGT TTGCTGGCTG CAAGAAGATC
TTTGGGAGCC TGGCATTTCT GCCGGAGAGC TTTGATGGGG ACCCAGCCTC CAACACTGCC
CCGCTCCAGC CAGAGCAGCT CCAAGTGTTT GAGACTCTGG AAGAGATCAC AGGTTACCTA
TACATCTCAG CATGGCCGGA CAGCCTGCCT GACCTCAGCG TCTTCCAGAA CCTGCAAGTA
ATCCGGGGAC GAATTCTGCA CAATGGCGCC TACTCGCTGA CCCTGCAAGG GCTGGGCATC
AGCTGGCTGG GGCTGCGCTC ACTGAGGGAA CTGGGCAGTG GACTGGCCCT CATCCACCAT
AACACCCACC TCTGCTTCGT GCACACGGTG CCCTGGGACC AGCTCTTTCG GAACCCGCAC
CAAGCTCTGC TCCACACTGC CAACCGGCCA GAGGACGAGT GTGTGGGCGA GGGCCTGGCC
TGCCACCAGC TGTGCGCCCG AGGGCACTGC TGGGGTCCAG GGCCCACCCA GTGTGTCAAC
TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC GTGGAGGAAT GCCGAGTACT GCAGGGGCTC
CCCAGGGAGT ATGTGAATGC CAGGCACTGT TTGCCGTGCC ACCCTGAGTG TCAGCCCCAG
AATGGCTCAG TGACCTGTTT TGGACCGGAG GCTGACCAGT GTGTGGCCTG TGCCCACTAT
AAGGACCCTC CCTTCTGCGT GGCCCGCTGC CCCAGCGGTG TGAAACCTGA CCTCTCCTAC
ATGCCCATCT GGAAGTTTCC AGATGAGGAG GGCGCATGCC AGCCTTGCCC CATCAACTGC
ACCCACTCCT GTGTGGACCT GGATGACAAG GGCTGCCCCG CCGAGCAGAG AGCCAGCCCT
CTGACGTCCA TCATCTCTGC GGTGGTTGGC ATTCTGCTGG TCGTGGTCTT GGGGGTGGTC
TTTGGGATCC TCATCAAGCG ACGGCAGCAG AAGATCCGGA AGTACACGAT GCGGAGACTG
CTGCAGGAAA CGGAGCTGGT GGAGCCGCTG ACACCTAGCG GAGCGATGCC CAACCAGGCG
CAGATGCGGA TCCTGAAAGA GACGGAGCTG AGGAAGGTGA AGGTGCTTGG ATCTGGCGCT
TTTGGCACAG TCTACAAGGG CATCTGGATC CCTGATGGGG AGAATGTGAA AATTCCAGTG
GCCATCAAAG TGTTGAGGGA AAACACATCC CCCAAAGCCA ACAAAGAAAT CTTAGACGAA
GCATACGTGA TGGCTGGTGT GGGCTCCCCA TATGTCTCCC GCCTTCTGGG CATCTGCCTG
ACATCCACGG TGCAGCTGGT GACACAGCTT ATGCCCTATG GCTGCCTCTT AGACCATGTC
CGGGAAAACC GCGGACGCCT GGGCTCCCAG GACCTGCTGA ACTGGTGTAT GCAGATTGCC
AAGGGGATGA GCTACCTGGA GGATGTGCGG CTCGTACACA GGGACTTGGC CGCTCGGAAC
GTGCTGGTCA AGAGTCCCAA CCATGTCAAA ATTACAGACT TCGGGCTGGC TCGGCTGCTG
GACATTGACG AGACAGAGTA CCATGCAGAT GGGGGCAAGG TGCCCATCAA GTGGATGGCG
CTGGAGTCCA TTCTCCGCCG GCGGTTCACC CACCAGAGTG ATGTGTGGAG TTATGGTGTG
ACTGTGTGGG AGCTGATGAC TTTTGGGGCC AAACCTTACG ATGGGATCCC AGCCCGGGAG
ATCCCTGACC TGCTGGAAAA GGGGGAGCGG CTGCCCCAGC CCCCCATCTG CACCATTGAT
GTCTACATGA TCATGGTCAA ATGTTGGATG ATTGACTCTG AATGTCGGCC AAGATTCCGG
GAGTTGGTGT CTGAATTCTC CCGCATGGCC AGGGACCCCC AGCGCTTTGT GGTCATCCAG
AATGAGGACT TGGGCCCAGC CAGTCCCTTG GACAGCACCT TCTACCGCTC ACTGCTGGAG
GACGATGACA TGGGGGACCT GGTGGATGCT GAGGAGTATC TGGTACCCCA GCAGGGCTTC
TTCTGTCCAG ACCCTGCCCC GGGCGCTGGG GGCATGGTCC ACCACAGGCA CCGCAGCTCA
TCTACCAGGA GTGGCGGTGG GGACCTGACA CTAGGGCTGG AGCCCTCTGA AGAGGAGGCC
CCCAGGTCTC CACTGGCACC CTCCGAAGGG GCTGGCTCCG ATGTATTTGA TGGTGACCTG
GGAATGGGGG CAGCCAAGGG GCTGCAAAGC CTCCCCACAC ATGACCCCAG CCCTCTACAG
CGGTACAGTG AGGACCCCAC AGTACCCCTG CCCTCTGAGA CTGATGGCTA CGTTGCCCCC
CTGACCTGCA GCCCCCAGCC TGAATATGTG AACCAGCCAG ATGTTCGGCC CCAGCCCCCT
TCGCCCCGAG AGGGCCCTCT GCCTGCTGCC CGACCTGCTG GTGCCACTCT GGAAAGGCCC
AAGACTCTCT CCCCAGGGAA GAATGGGGTC GTCAAAGACG TTTTTGCCTT TGGGGGTGCC
GTGGAGAACC CCGAGTACTT GACACCCCAG GGAGGAGCTG CCCCTCAGCC CCACCCTCCT
CCTGCCTTCA GCCCAGCCTT CGACAACCTC TATTACTGGG ACCAGGACCC ACCAGAGCGG
GGGGCTCCAC CCAGCACCTT CAAAGGGACA CCTACGGCAG AGAACCCAGA GTACCTGGGT
CTGGACGTGC CAGTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001005862.1
CDS577..4254
Misc Feature(1)556..558(+)
Misc Feature(2)640..1005(+)
Misc Feature(3)1051..1515(+)
Misc Feature(4)1189..1326(+)
Misc Feature(5)1582..1944(+)
Misc Feature(6)2014..>2118(+)
Misc Feature(7)2017..2415(+)
Misc Feature(8)2170..2307(+)
Misc Feature(9)2407..2538(+)
Misc Feature(10)2413..2487(+)
Misc Feature(11)2416..2499(+)
Misc Feature(12)2620..3456(+)
Misc Feature(13)2644..3414(+)
Misc Feature(14)2662..3177(+)
Misc Feature(15)2662..3075(+)
Misc Feature(16)3070..3147(+)
Misc Feature(17)3136..3177(+)
Misc Feature(18)3553..3555(+)
Misc Feature(19)3901..3903(+)
Misc Feature(20)4072..4074(+)
Misc Feature(21)4147..4149(+)
Misc Feature(22)4150..4152(+)
Misc Feature(23)4228..4230(+)
Misc Feature(24)4228..4230(+)
Misc Feature(25)4228..4230(+)
Exon (1)1..195
Gene:ERBB2
Gene Synonym:
Exon (2)196..300
Gene:ERBB2
Gene Synonym:
Exon (3)301..365
Gene:ERBB2
Gene Synonym:
Exon (4)366..559
Gene:ERBB2
Gene Synonym:
Exon (5)560..711
Gene:ERBB2
Gene Synonym:
Exon (6)712..925
Gene:ERBB2
Gene Synonym:
Exon (7)926..1060
Gene:ERBB2
Gene Synonym:
Exon (8)1061..1129
Gene:ERBB2
Gene Synonym:
Exon (9)1130..1245
Gene:ERBB2
Gene Synonym:
Exon (10)1246..1387
Gene:ERBB2
Gene Synonym:
Exon (11)1388..1507
Gene:ERBB2
Gene Synonym:
Exon (12)1508..1634
Gene:ERBB2
Gene Synonym:
Exon (13)1635..1708
Gene:ERBB2
Gene Synonym:
Exon (14)1709..1799
Gene:ERBB2
Gene Synonym:
Exon (15)1800..1999
Gene:ERBB2
Gene Synonym:
Exon (16)2000..2132
Gene:ERBB2
Gene Synonym:
Exon (17)2133..2223
Gene:ERBB2
Gene Synonym:
Exon (18)2224..2384
Gene:ERBB2
Gene Synonym:
Exon (19)2385..2432
Gene:ERBB2
Gene Synonym:
Exon (20)2433..2571
Gene:ERBB2
Gene Synonym:
Exon (21)2572..2694
Gene:ERBB2
Gene Synonym:
Exon (22)2695..2793
Gene:ERBB2
Gene Synonym:
Exon (23)2794..2979
Gene:ERBB2
Gene Synonym:
Exon (24)2980..3135
Gene:ERBB2
Gene Synonym:
Exon (25)3136..3211
Gene:ERBB2
Gene Synonym:
Exon (26)3212..3358
Gene:ERBB2
Gene Synonym:
Exon (27)3359..3456
Gene:ERBB2
Gene Synonym:
Exon (28)3457..3645
Gene:ERBB2
Gene Synonym:
Exon (29)3646..3898
Gene:ERBB2
Gene Synonym:
Exon (30)3899..4872
Gene:ERBB2
Gene Synonym:
Translation
Position Chain Variation Link
3 3 a, g dbSNP:56350074
18 18 a, t dbSNP:563212698
23 23 a, c dbSNP:541182612
29 29 a, c dbSNP:573315299
39 39 c, t dbSNP:77251976
42 42 a, g dbSNP:771589861
59 59 c, t dbSNP:80085819
95 95 a, c dbSNP:769873219
138 138 -, g dbSNP:35771148
154 154 a, g dbSNP:548386033
210 210 a, c dbSNP:117641771
300 300 a, g dbSNP:767616586
321 321 c, t dbSNP:773237824
356 356 g, t dbSNP:749336016
363 363 a, g dbSNP:187431136
436 436 a, g dbSNP:8182267
501 501 c, t dbSNP:570384007
508 508 a, g dbSNP:781492194
536 536 a, g dbSNP:559759528
545 545 a, g dbSNP:748546362
560 560 c, t dbSNP:755921683
565 565 a, c dbSNP:779913120
567 567 c, t dbSNP:377542789
568 568 a, g dbSNP:564064363
570 570 c, g dbSNP:528118039
574 574 g, t dbSNP:778487069
579 579 g, t dbSNP:546886845
583 583 c, t dbSNP:771576995
585 585 a, g dbSNP:4252610
586 586 c, t dbSNP:149937802
588 588 a, g dbSNP:369293607
590 590 c, t dbSNP:777171280
591 591 c, t dbSNP:759935065
595 595 c, g dbSNP:765607521
603 603 c, t dbSNP:775826753
604 604 a, g dbSNP:763193414
619 619 a, g dbSNP:587778266
623 623 c, t dbSNP:764222200
626 626 a, g dbSNP:144019910
656 656 a, g dbSNP:140441229
667 667 c, g dbSNP:766186178
674 674 c, t dbSNP:753655456
678 678 c, t dbSNP:754742686
685 685 a, g dbSNP:778575008
686 686 c, t dbSNP:752339377
689 689 a, g dbSNP:757899978
692 692 c, g dbSNP:777347427
696 696 -, c dbSNP:754691039
711 711 -, g dbSNP:780661804
722 722 a, c dbSNP:61737968
735 735 c, t dbSNP:191376350
736 736 a, g dbSNP:376524324
742 742 a, g dbSNP:759478535
744 744 c, t dbSNP:147785188
745 745 a, g dbSNP:775382058
750 750 a, c dbSNP:762638680
755 755 a, c dbSNP:763850846
759 759 a, g dbSNP:369499945
768 768 a, c dbSNP:756850857
770 770 c, t dbSNP:767151455
784 784 c, t dbSNP:749886389
785 785 a, g dbSNP:756720659
788 788 c, t dbSNP:539140755
798 798 c, t dbSNP:576471733
815 815 a, g dbSNP:749711404
819 819 c, t dbSNP:755265117
826 826 c, t dbSNP:372811772
830 830 c, t dbSNP:748301823
831 831 c, t dbSNP:200102353
837 837 a, g dbSNP:370676964
843 843 c, t dbSNP:747047846
847 847 a, g dbSNP:769775277
850 850 c, g dbSNP:141135746
851 851 c, t dbSNP:370959592
852 852 a, g dbSNP:762875937
853 853 c, t dbSNP:763786330
867 867 c, g dbSNP:4252613
868 868 c, g dbSNP:761564667
869 869 c, g dbSNP:373824622
870 870 c, g, t dbSNP:749976401
871 871 g, t dbSNP:766949725
886 886 c, t dbSNP:754295165
892 892 a, g dbSNP:755427616
896 896 c, t dbSNP:200208742
898 898 c, t dbSNP:779156384
899 899 a, g dbSNP:748476466
903 903 g, t dbSNP:758646541
914 914 a, g dbSNP:185670819
919 919 c, t dbSNP:527779103
938 938 g, t dbSNP:200963868
941 941 c, g dbSNP:151122410
942 942 a, g dbSNP:758734557
943 943 c, g dbSNP:778041266
945 945 c, t dbSNP:751770717
948 948 c, g dbSNP:757446217
955 955 c, t dbSNP:781137961
956 956 a, g dbSNP:745921471
960 960 c, t dbSNP:768502081
961 961 a, c dbSNP:778888794
967 967 c, g dbSNP:774604250
972 972 c, t dbSNP:775319988
977 977 a, g dbSNP:747995543
979 979 c, g dbSNP:771986239
984 984 a, g dbSNP:370810322
1008 1008 c, t dbSNP:141086703
1014 1014 c, t dbSNP:56114611
1016 1016 a, g dbSNP:776032539
1023 1023 a, g dbSNP:146844678
1048 1048 a, c, t dbSNP:765706190
1049 1049 a, g dbSNP:763371007
1054 1054 c, t dbSNP:753419830
1055 1055 a, g dbSNP:531563820
1065 1065 c, g, t dbSNP:769335702
1066 1066 c, t dbSNP:763458661
1067 1067 c, t dbSNP:764545872
1076 1076 c, t dbSNP:113619125
1077 1077 a, g dbSNP:762217415
1080 1080 a, g dbSNP:767673890
1088 1088 g, t dbSNP:750651941
1116 1116 a, g dbSNP:756204333
1119 1119 c, t dbSNP:766580117
1127 1127 g, t dbSNP:753902254
1129 1129 c, t dbSNP:577260523
1133 1133 c, t dbSNP:770976272
1134 1134 a, g dbSNP:779058669
1135 1135 c, t dbSNP:768151310
1136 1136 a, g dbSNP:779346332
1149 1149 c, t dbSNP:748701236
1150 1150 a, g dbSNP:772393268
1161 1161 c, g dbSNP:140636713
1162 1162 c, t dbSNP:760895559
1163 1163 a, g dbSNP:745625627
1174 1174 c, t dbSNP:776960538
1180 1180 a, c dbSNP:759753872
1203 1203 a, g dbSNP:765424712
1207 1207 a, g dbSNP:752656997
1213 1213 a, g dbSNP:533090552
1214 1214 g, t dbSNP:767309845
1220 1220 c, t dbSNP:376183465
1221 1221 a, g dbSNP:755873891
1234 1234 c, t dbSNP:779750598
1253 1253 c, t dbSNP:777081311
1254 1254 c, t dbSNP:759845382
1262 1262 a, g dbSNP:769870618
1263 1263 c, t dbSNP:775666242
1264 1264 c, t dbSNP:762919589
1271 1271 a, g dbSNP:548076348
1273 1273 a, t dbSNP:750324803
1275 1275 c, t dbSNP:760523023
1278 1278 c, t dbSNP:368210132
1281 1281 a, g dbSNP:530186646
1285 1285 c, t dbSNP:773759626
1294 1294 g, t dbSNP:200382130
1295 1295 c, t dbSNP:754656388
1296 1296 c, t dbSNP:764747320
1304 1304 c, t dbSNP:752295912
1319 1319 a, c dbSNP:757811990
1330 1330 a, c dbSNP:778408285
1341 1341 c, t dbSNP:747503021
1342 1342 a, g dbSNP:149210045
1349 1349 a, g dbSNP:760205387
1354 1354 a, g dbSNP:746190897
1359 1359 c, t dbSNP:770104901
1360 1360 a, g dbSNP:775544453
1362 1362 c, t dbSNP:749453104
1391 1391 a, t dbSNP:768855063
1395 1395 c, t dbSNP:774443757
1398 1398 c, t dbSNP:748176467
1407 1407 c, t dbSNP:770903497
1408 1408 a, g dbSNP:776515406
1413 1413 a, t dbSNP:145697136
1425 1425 c, t dbSNP:138280629
1426 1426 a, g dbSNP:775294491
1438 1438 c, t dbSNP:762547363
1452 1452 g, t dbSNP:546000185
1469 1469 a, c, t dbSNP:763793826
1474 1474 c, t dbSNP:761376658
1475 1475 a, g dbSNP:768206712
1478 1478 a, g dbSNP:564382616
1482 1482 a, g dbSNP:756588194
1485 1485 a, g dbSNP:780283935
1487 1487 -, g dbSNP:769703068
1488 1488 c, t dbSNP:754188777
1505 1505 a, g dbSNP:532077147
1512 1512 c, t dbSNP:778968985
1514 1514 a, g dbSNP:747993530
1516 1516 c, g dbSNP:758204762
1521 1521 a, g dbSNP:777348537
1526 1526 a, t dbSNP:746686273
1534 1534 c, t dbSNP:770421665
1536 1536 a, c, g dbSNP:559242250
1537 1537 a, c dbSNP:770327076
1538 1538 a, g dbSNP:775972596
1541 1541 a, g dbSNP:763367024
1543 1543 g, t dbSNP:769082334
1551 1551 a, g dbSNP:190567339
1565 1565 a, t dbSNP:373474372
1566 1566 c, t dbSNP:762129422
1582 1582 c, g dbSNP:767588058
1584 1584 c, g dbSNP:750577335
1593 1593 a, g dbSNP:760803727
1599 1599 c, t dbSNP:149567593
1609 1609 a, g dbSNP:752664566
1619 1619 c, t dbSNP:758210687
1620 1620 a, g dbSNP:143225142
1624 1624 a, g dbSNP:148068883
1634 1634 a, g dbSNP:751270411
1636 1636 a, g dbSNP:753902259
1638 1638 c, t dbSNP:199514902
1643 1643 a, c, g dbSNP:141116145
1644 1644 c, t dbSNP:756999086
1648 1648 a, c dbSNP:780881510
1649 1649 a, g dbSNP:750090147
1654 1654 a, g dbSNP:755701444
1655 1655 c, t dbSNP:587778264
1656 1656 c, t dbSNP:544011927
1658 1658 c, t dbSNP:748700504
1659 1659 a, c, g dbSNP:769257889
1662 1662 c, g dbSNP:562384569
1665 1665 a, g dbSNP:147204600
1667 1667 c, t dbSNP:772548631
1679 1679 a, g dbSNP:773649491
1681 1681 a, g dbSNP:747239268
1693 1693 a, c, t dbSNP:377649991
1695 1695 a, g dbSNP:776871033
1717 1717 g, t dbSNP:587778265
1720 1720 a, g dbSNP:758908894
1728 1728 a, c, g dbSNP:373728539
1733 1733 c, t dbSNP:747327229
1734 1734 a, g dbSNP:140507994
1736 1736 a, c dbSNP:776714622
1742 1742 g, t dbSNP:746020984
1750 1750 a, c dbSNP:769778398
1753 1753 a, g dbSNP:199668084
1755 1755 c, t dbSNP:35757908
1756 1756 a, g dbSNP:142783371
1774 1774 a, g dbSNP:767398280
1780 1780 c, t dbSNP:367606199
1787 1787 a, g dbSNP:147382623
1795 1795 c, t dbSNP:766083302
1803 1803 c, t dbSNP:750754275
1804 1804 a, g dbSNP:756345214
1806 1806 a, c dbSNP:780294548
1811 1811 c, t dbSNP:749440298
1812 1812 g, t dbSNP:4252632
1818 1818 a, c dbSNP:778904008
1821 1821 a, g dbSNP:746949970
1834 1834 a, g dbSNP:770857517
1842 1842 g, t dbSNP:4252633
1843 1843 c, g dbSNP:759352819
1852 1852 c, t dbSNP:200497646
1857 1857 a, g dbSNP:2230698
1858 1858 c, t dbSNP:368989970
1871 1871 a, g, t dbSNP:373192991
1883 1883 c, t dbSNP:751074421
1895 1895 a, g dbSNP:201097345
1901 1901 c, t dbSNP:768049972
1902 1902 c, t dbSNP:61737967
1903 1903 c, g dbSNP:756500045
1912 1912 g, t dbSNP:780201941
1914 1914 c, t dbSNP:532023577
1915 1915 a, g dbSNP:755121772
1922 1922 c, t dbSNP:201021373
1926 1926 a, g dbSNP:748176472
1928 1928 c, t dbSNP:370565888
1929 1929 c, g, t dbSNP:55984118
1933 1933 a, g dbSNP:571837012
1944 1944 c, t dbSNP:539260608
1945 1945 c, t dbSNP:375382055
1946 1946 a, c, g dbSNP:371450390
1950 1950 a, c dbSNP:768374532
1952 1952 c, t dbSNP:142456637
1953 1953 a, g dbSNP:147076339
1957 1957 c, g, t dbSNP:140670446
1973 1973 c, t dbSNP:767978749
1975 1975 a, g dbSNP:145762641
1981 1981 a, c, g, t dbSNP:199530208
1982 1982 a, g, t dbSNP:182572604
1992 1992 c, t dbSNP:752759368
1993 1993 a, g dbSNP:758497995
2016 2016 c, g dbSNP:765510261
2031 2031 c, t dbSNP:368632077
2032 2032 a, g dbSNP:371623072
2036 2036 a, g dbSNP:759579850
2040 2040 a, g dbSNP:199657476
2051 2051 a, g dbSNP:561322621
2053 2053 c, t dbSNP:202202058
2055 2055 a, g dbSNP:55928971
2064 2064 c, g, t dbSNP:754811013
2071 2071 a, g dbSNP:747838206
2075 2075 a, g dbSNP:771580372
2077 2077 c, t dbSNP:140711914
2080 2080 a, c dbSNP:777363214
2089 2089 c, t dbSNP:746476368
2093 2093 a, g dbSNP:140980495
2100 2100 g, t dbSNP:777116958
2106 2106 c, t dbSNP:371585581
2110 2110 g, t dbSNP:770157051
2118 2118 c, t dbSNP:775678910
2120 2120 a, g dbSNP:150203173
2128 2128 a, c, t dbSNP:565582943
2131 2131 g, t dbSNP:532713027
2133 2133 g, t dbSNP:775974838
2136 2136 c, t dbSNP:763197991
2145 2145 a, g dbSNP:768992351
2148 2148 c, t dbSNP:774426489
2151 2151 a, g dbSNP:762073749
2163 2163 c, g, t dbSNP:767713671
2167 2167 c, t dbSNP:369690252
2171 2171 c, t dbSNP:201470725
2172 2172 a, c, g dbSNP:4252635
2192 2192 c, t dbSNP:763863372
2199 2199 c, t dbSNP:149337787
2201 2201 g, t dbSNP:756836001
2211 2211 a, c, t dbSNP:780703792
2216 2216 g, t dbSNP:778479390
2222 2222 c, t dbSNP:756686824
2232 2232 c, t dbSNP:138893464
2258 2258 a, t dbSNP:767216520
2264 2264 c, t dbSNP:750092447
2267 2267 a, c dbSNP:760310908
2268 2268 a, c dbSNP:765842816
2274 2274 c, t dbSNP:753344199
2275 2275 a, g dbSNP:755483857
2279 2279 a, c, g dbSNP:145409713
2281 2281 c, t dbSNP:369903296
2282 2282 a, g dbSNP:758820578
2283 2283 c, g dbSNP:778223078
2292 2292 c, t dbSNP:747200104
2293 2293 a, g dbSNP:771145294
2294 2294 a, g dbSNP:781179380
2301 2301 a, g dbSNP:538900246
2310 2310 c, t dbSNP:768648444
2314 2314 c, t dbSNP:774261411
2317 2317 a, g dbSNP:377370642
2331 2331 a, g dbSNP:771862037
2343 2343 a, g dbSNP:142816898
2349 2349 c, t dbSNP:760271180
2350 2350 a, g dbSNP:766029214
2352 2352 a, g dbSNP:753325392
2360 2360 c, t dbSNP:759078493
2361 2361 c, t dbSNP:765900638
2371 2371 a, g dbSNP:753267835
2372 2372 a, c dbSNP:758907167
2380 2380 c, t dbSNP:778312796
2384 2384 c, t dbSNP:199726056
2412 2412 c, t dbSNP:541854282
2414 2414 c, g dbSNP:367599823
2415 2415 c, g, t dbSNP:56110910
2416 2416 a, g dbSNP:750665964
2418 2418 c, t dbSNP:141678288
2419 2419 a, g dbSNP:370514427
2426 2426 a, c, g dbSNP:201784472
2428 2428 a, g dbSNP:777759226
2435 2435 c, t dbSNP:778798172
2436 2436 c, t dbSNP:746968535
2437 2437 c, t dbSNP:757101082
2445 2445 c, t dbSNP:374222106
2446 2446 a, c, g dbSNP:1801201
2448 2448 c, t dbSNP:779841027
2449 2449 a, g, t dbSNP:1136201
2451 2451 c, t dbSNP:768217764
2454 2454 g, t dbSNP:577329788
2467 2467 a, g dbSNP:762407538
2478 2478 c, g dbSNP:772440208
2487 2487