The following ERCC5 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ERCC5 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||Documents for ORF clone product in dufault vector
||ORF Nucleotide Sequence (Length: 3561bp)
||pcDNA3.1+/C-(K)DYK or customized vector
||Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
||Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Document: OHu20331D_COA.pdf (pdf)
||Homo sapiens (human)
||DNA repair protein complementing XP-G cells
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA195001.1, X69978.1,
BQ002437.1 and BE223050.1.
This sequence is a reference standard in the RefSeqGene project.
On Mar 1, 2011 this sequence version replaced gi:51988899.
Summary: This gene encodes a single-strand specific DNA
endonuclease that makes the 3' incision in DNA excision repair
following UV-induced damage. The protein may also function in other
cellular processes, including RNA polymerase II transcription, and
transcription-coupled DNA repair. Mutations in this gene cause
xeroderma pigmentosum complementation group G (XP-G), which is also
referred to as xeroderma pigmentosum VII (XP7), a skin disorder
characterized by hypersensitivity to UV light and increased
susceptibility for skin cancer development following UV exposure.
Some patients also develop Cockayne syndrome, which is
characterized by severe growth defects, mental retardation, and
cachexia. Read-through transcription exists between this gene and
the neighboring upstream BIVM (basic, immunoglobulin-like variable
motif containing) gene. [provided by RefSeq, Feb 2011].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC031522.2, AF462447.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.