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ABCA3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol ABCA3
Entrez Gene ID 21
Full Name ATP-binding cassette, sub-family A (ABC1), member 3
Synonyms ABC-C, ABC3, EST111653, LBM180, SMDP3
General protein information
Preferred Names
ATP-binding cassette sub-family A member 3
Names
ATP-binding cassette sub-family A member 3
ABC transporter 3
ABC-C transporter
ATP-binding cassette transporter 3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p13.3

Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

601615

Disorder Html: Surfactant metabolism dysfunction, pulmonary, 3, 610921 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_001089 NP_001080 ATP-binding cassette sub-family A member 3



Homo sapiens (human) ABCA3 NP_001080.2
Pan troglodytes (chimpanzee) ABCA3 XP_510744.2
Canis lupus familiaris (dog) ABCA3 XP_005621743.1
Bos taurus (cattle) ABCA3 NP_001107218.1
Mus musculus (house mouse) Abca3 NP_001034670.1
Rattus norvegicus (Norway rat) Abca3 XP_006246102.1
Gallus gallus (chicken) ABCA3 XP_004945493.1
Danio rerio (zebrafish) abca3b XP_002661144.3
Drosophila melanogaster (fruit fly) CG1718 NP_001259764.1
Caenorhabditis elegans abt-4 NP_503175.1
Xenopus (Silurana) tropicalis (western clawed frog) abca3 XP_002932496.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ABCA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABCA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu24147
NM_001089 Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 3 (ABCA3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$659.50-$923.30
$1319.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu24147
Clone ID Related Accession (Same CDS sequence) NM_001089
Accession Version NM_001089.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 5115bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ATP-binding cassette sub-family A member 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106820.4, DA109409.1, U78735.1, BC020724.1, AB210044.1 and BP397501.1. This sequence is a reference standard in the RefSeqGene project. On Oct 26, 2006 this sequence version replaced gi:4501848. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC151840.1, U78735.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
ATGGCTGTGC TCAGGCAGCT GGCGCTCCTC CTCTGGAAGA ACTACACCCT GCAGAAGCGG 
AAGGTCCTGG TGACGGTCCT GGAACTCTTC CTGCCATTGC TGTTTTCTGG GATCCTCATC
TGGCTCCGCT TGAAGATTCA GTCGGAAAAT GTGCCCAACG CCACCATCTA CCCGGGCCAG
TCCATCCAGG AGCTGCCTCT GTTCTTCACC TTCCCTCCGC CAGGAGACAC CTGGGAGCTT
GCCTACATCC CTTCTCACAG TGACGCTGCC AAGACCGTCA CTGAGACAGT GCGCAGGGCA
CTTGTGATCA ACATGCGAGT GCGCGGCTTT CCCTCCGAGA AGGACTTTGA GGACTACATT
AGGTACGACA ACTGCTCGTC CAGCGTGCTG GCCGCCGTGG TCTTCGAGCA CCCCTTCAAC
CACAGCAAGG AGCCCCTGCC GCTGGCGGTG AAATATCACC TACGGTTCAG TTACACACGG
AGAAATTACA TGTGGACCCA AACAGGCTCC TTTTTCCTGA AAGAGACAGA AGGCTGGCAC
ACTACTTCCC TTTTCCCGCT TTTCCCAAAC CCAGGACCAA GGGAACCTAC ATCCCCTGAT
GGCGGAGAAC CTGGGTACAT CCGGGAAGGC TTCCTGGCCG TGCAGCATGC TGTGGACCGG
GCCATCATGG AGTACCATGC CGATGCCGCC ACACGCCAGC TGTTCCAGAG ACTGACGGTG
ACCATCAAGA GGTTCCCGTA CCCGCCGTTC ATCGCAGACC CCTTCCTCGT GGCCATCCAG
TACCAGCTGC CCCTGCTGCT GCTGCTCAGC TTCACCTACA CCGCGCTCAC CATTGCCCGT
GCTGTCGTGC AGGAGAAGGA AAGGAGGCTG AAGGAGTACA TGCGCATGAT GGGGCTCAGC
AGCTGGCTGC ACTGGAGTGC CTGGTTCCTC TTGTTCTTCC TCTTCCTCCT CATCGCCGCC
TCCTTCATGA CCCTGCTCTT CTGTGTCAAG GTGAAGCCAA ATGTAGCCGT GCTGTCCCGC
AGCGACCCCT CCCTGGTGCT CGCCTTCCTG CTGTGCTTCG CCATCTCTAC CATCTCCTTC
AGCTTCATGG TCAGCACCTT CTTCAGCAAA GCCAACATGG CAGCAGCCTT CGGAGGCTTC
CTCTACTTCT TCACCTACAT CCCCTACTTC TTCGTGGCCC CTCGGTACAA CTGGATGACT
CTGAGCCAGA AGCTCTGCTC CTGCCTCCTG TCTAATGTCG CCATGGCAAT GGGAGCCCAG
CTCATTGGGA AATTTGAGGC GAAAGGCATG GGCATCCAGT GGCGAGACCT CCTGAGTCCC
GTCAACGTGG ACGACGACTT CTGCTTCGGG CAGGTGCTGG GGATGCTGCT GCTGGACTCT
GTGCTCTATG GCCTGGTGAC CTGGTACATG GAGGCCGTCT TCCCAGGGCA GTTCGGCGTG
CCTCAGCCCT GGTACTTCTT CATCATGCCC TCCTATTGGT GTGGGAAGCC AAGGGCGGTT
GCAGGGAAGG AGGAAGAAGA CAGTGACCCC GAGAAAGCAC TCAGAAACGA GTACTTTGAA
GCCGAGCCAG AGGACCTGGT GGCGGGGATC AAGATCAAGC ACCTGTCCAA GGTGTTCAGG
GTGGGAAATA AGGACAGGGC GGCCGTCAGA GACCTGAACC TCAACCTGTA CGAGGGACAG
ATCACCGTCC TGCTGGGCCA CAACGGTGCC GGGAAGACCA CCACCCTCTC CATGCTCACA
GGTCTCTTTC CCCCCACCAG TGGACGGGCA TACATCAGCG GGTATGAAAT TTCCCAGGAC
ATGGTTCAGA TCCGGAAGAG CCTGGGCCTG TGCCCGCAGC ACGACATCCT GTTTGACAAC
TTGACAGTCG CAGAGCACCT TTATTTCTAC GCCCAGCTGA AGGGCCTGTC ACGTCAGAAG
TGCCCTGAAG AAGTCAAGCA GATGCTGCAC ATCATCGGCC TGGAGGACAA GTGGAACTCA
CGGAGCCGCT TCCTGAGCGG GGGCATGAGG CGCAAGCTCT CCATCGGCAT CGCCCTCATC
GCAGGCTCCA AGGTGCTGAT ACTGGACGAG CCCACCTCGG GCATGGACGC CATCTCCAGG
AGGGCCATCT GGGATCTTCT TCAGCGGCAG AAAAGTGACC GCACCATCGT GCTGACCACC
CACTTCATGG ACGAGGCTGA CCTGCTGGGA GACCGCATCG CCATCATGGC CAAGGGGGAG
CTGCAGTGCT GCGGGTCCTC GCTGTTCCTC AAGCAGAAAT ACGGTGCCGG CTATCACATG
ACGCTGGTGA AGGAGCCGCA CTGCAACCCG GAAGACATCT CCCAGCTGGT CCACCACCAC
GTGCCCAACG CCACGCTGGA GAGCAGCGCT GGGGCCGAGC TGTCTTTCAT CCTTCCCAGA
GAGAGCACGC ACAGGTTTGA AGGTCTCTTT GCTAAACTGG AGAAGAAGCA GAAAGAGCTG
GGCATTGCCA GCTTTGGGGC ATCCATCACC ACCATGGAGG AAGTCTTCCT TCGGGTCGGG
AAGCTGGTGG ACAGCAGTAT GGACATCCAG GCCATCCAGC TCCCTGCCCT GCAGTACCAG
CACGAGAGGC GCGCCAGCGA CTGGGCTGTG GACAGCAACC TCTGTGGGGC CATGGACCCC
TCCGACGGCA TTGGAGCCCT CATCGAGGAG GAGCGCACCG CTGTCAAGCT CAACACTGGG
CTCGCCCTGC ACTGCCAGCA ATTCTGGGCC ATGTTCCTGA AGAAGGCCGC ATACAGCTGG
CGCGAGTGGA AAATGGTGGC GGCACAGGTC CTGGTGCCTC TGACCTGCGT CACCCTGGCC
CTCCTGGCCA TCAACTACTC CTCGGAGCTC TTCGACGACC CCATGCTGAG GCTGACCTTG
GGCGAGTACG GCAGAACCGT CGTGCCCTTC TCAGTTCCCG GGACCTCCCA GCTGGGTCAG
CAGCTGTCAG AGCATCTGAA AGACGCACTG CAGGCTGAGG GACAGGAGCC CCGCGAGGTG
CTCGGTGACC TGGAGGAGTT CTTGATCTTC AGGGCTTCTG TGGAGGGGGG CGGCTTTAAT
GAGCGGTGCC TTGTGGCAGC GTCCTTCAGA GATGTGGGAG AGCGCACGGT CGTCAACGCC
TTGTTCAACA ACCAGGCGTA CCACTCTCCA GCCACTGCCC TGGCCGTCGT GGACAACCTT
CTGTTCAAGC TGCTGTGCGG GCCTCACGCC TCCATTGTGG TCTCCAACTT CCCCCAGCCC
CGGAGCGCCC TGCAGGCTGC CAAGGACCAG TTTAACGAGG GCCGGAAGGG ATTCGACATT
GCCCTCAACC TGCTCTTCGC CATGGCATTC TTGGCCAGCA CGTTCTCCAT CCTGGCGGTC
AGCGAGAGGG CCGTGCAGGC CAAGCATGTG CAGTTTGTGA GTGGAGTCCA CGTGGCCAGT
TTCTGGCTCT CTGCTCTGCT GTGGGACCTC ATCTCCTTCC TCATCCCCAG TCTGCTGCTG
CTGGTGGTGT TTAAGGCCTT CGACGTGCGT GCCTTCACGC GGGACGGCCA CATGGCTGAC
ACCCTGCTGC TGCTCCTGCT CTACGGCTGG GCCATCATCC CCCTCATGTA CCTGATGAAC
TTCTTCTTCT TGGGGGCGGC CACTGCCTAC ACGAGGCTGA CCATCTTCAA CATCCTGTCA
GGCATCGCCA CCTTCCTGAT GGTCACCATC ATGCGCATCC CAGCTGTAAA ACTGGAAGAA
CTTTCCAAAA CCCTGGATCA CGTGTTCCTG GTGCTGCCCA ACCACTGTCT GGGGATGGCA
GTCAGCAGTT TCTACGAGAA CTACGAGACG CGGAGGTACT GCACCTCCTC CGAGGTCGCC
GCCCACTACT GCAAGAAATA TAACATCCAG TACCAGGAGA ACTTCTATGC CTGGAGCGCC
CCGGGGGTCG GCCGGTTTGT GGCCTCCATG GCCGCCTCAG GGTGCGCCTA CCTCATCCTG
CTCTTCCTCA TCGAGACCAA CCTGCTTCAG AGACTCAGGG GCATCCTCTG CGCCCTCCGG
AGGAGGCGGA CACTGACAGA ATTATACACC CGGATGCCTG TGCTTCCTGA GGACCAAGAT
GTAGCGGACG AGAGGACCCG CATCCTGGCC CCCAGCCCGG ACTCCCTGCT CCACACACCT
CTGATTATCA AGGAGCTCTC CAAGGTGTAC GAGCAGCGGG TGCCCCTCCT GGCCGTGGAC
AGGCTCTCCC TCGCGGTGCA GAAAGGGGAG TGCTTCGGCC TGCTGGGCTT CAATGGAGCC
GGGAAGACCA CGACTTTCAA AATGCTGACC GGGGAGGAGA GCCTCACTTC TGGGGATGCC
TTTGTCGGGG GTCACAGAAT CAGCTCTGAT GTCGGAAAGG TGCGGCAGCG GATCGGCTAC
TGCCCGCAGT TTGATGCCTT GCTGGACCAC ATGACAGGCC GGGAGATGCT GGTCATGTAC
GCTCGGCTCC GGGGCATCCC TGAGCGCCAC ATCGGGGCCT GCGTGGAGAA CACTCTGCGG
GGCCTGCTGC TGGAGCCACA TGCCAACAAG CTGGTCAGGA CGTACAGTGG TGGTAACAAG
CGGAAGCTGA GCACCGGCAT CGCCCTGATC GGAGAGCCTG CTGTCATCTT CCTGGACGAG
CCGTCCACTG GCATGGACCC CGTGGCCCGG CGCCTGCTTT GGGACACCGT GGCACGAGCC
CGAGAGTCTG GCAAGGCCAT CATCATCACC TCCCACAGCA TGGAGGAGTG TGAGGCCCTG
TGCACCCGGC TGGCCATCAT GGTGCAGGGG CAGTTCAAGT GCCTGGGCAG CCCCCAGCAC
CTCAAGAGCA AGTTCGGCAG CGGCTACTCC CTGCGGGCCA AGGTGCAGAG TGAAGGGCAA
CAGGAGGCGC TGGAGGAGTT CAAGGCCTTC GTGGACCTGA CCTTTCCAGG CAGCGTCCTG
GAAGATGAGC ACCAAGGCAT GGTCCATTAC CACCTGCCGG GCCGTGACCT CAGCTGGGCG
AAGGTTTTCG GTATTCTGGA GAAAGCCAAG GAAAAGTACG GCGTGGACGA CTACTCCGTG
AGCCAGATCT CGCTGGAACA GGTCTTCCTG AGCTTCGCCC ACCTGCAGCC GCCCACCGCA
GAGGAGGGGC GATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001080.2
CDS713..5827
Misc Feature(1)524..526(+)
Misc Feature(2)776..838(+)
Misc Feature(3)1493..1561(+)
Misc Feature(4)1523..2119(+)
Misc Feature(5)1631..1693(+)
Misc Feature(6)1742..1804(+)
Misc Feature(7)1829..1891(+)
Misc Feature(8)1925..1987(+)
Misc Feature(9)2051..2113(+)
Misc Feature(10)2300..3229(+)
Misc Feature(11)2300..2965(+)
Misc Feature(12)2408..2431(+)
Misc Feature(13)2417..2875(+)
Misc Feature(14)2540..2551(+)
Misc Feature(15)2705..2734(+)
Misc Feature(16)2765..2782(+)
Misc Feature(17)2789..2800(+)
Misc Feature(18)2861..2881(+)
Misc Feature(19)3485..3547(+)
Misc Feature(20)3986..4516(+)
Misc Feature(21)4010..4072(+)
Misc Feature(22)4142..4204(+)
Misc Feature(23)4259..4321(+)
Misc Feature(24)4349..4411(+)
Misc Feature(25)4445..4507(+)
Misc Feature(26)4505..4507(+)
Misc Feature(27)4514..4516(+)
Misc Feature(28)4628..4690(+)
Misc Feature(29)4853..5518(+)
Misc Feature(30)4901..5788(+)
Misc Feature(31)4958..4981(+)
Misc Feature(32)4967..5428(+)
Misc Feature(33)5090..5101(+)
Misc Feature(34)5255..5284(+)
Misc Feature(35)5315..5332(+)
Misc Feature(36)5339..5350(+)
Misc Feature(37)5414..5434(+)
Exon (1)1..174
Gene:ABCA3
Gene Synonym:
Exon (2)175..381
Gene:ABCA3
Gene Synonym:
Exon (3)382..686
Gene:ABCA3
Gene Synonym:
Exon (4)687..766
Gene:ABCA3
Gene Synonym:
Exon (5)767..1031
Gene:ABCA3
Gene Synonym:
Exon (6)1032..1159
Gene:ABCA3
Gene Synonym:
Exon (7)1160..1325
Gene:ABCA3
Gene Synonym:
Exon (8)1326..1585
Gene:ABCA3
Gene Synonym:
Exon (9)1586..1702
Gene:ABCA3
Gene Synonym:
Exon (10)1703..1823
Gene:ABCA3
Gene Synonym:
Exon (11)1824..1997
Gene:ABCA3
Gene Synonym:
Exon (12)1998..2179
Gene:ABCA3
Gene Synonym:
Exon (13)2180..2323
Gene:ABCA3
Gene Synonym:
Exon (14)2324..2453
Gene:ABCA3
Gene Synonym:
Exon (15)2454..2608
Gene:ABCA3
Gene Synonym:
Exon (16)2609..2764
Gene:ABCA3
Gene Synonym:
Exon (17)2765..2975
Gene:ABCA3
Gene Synonym:
Exon (18)2976..3126
Gene:ABCA3
Gene Synonym:
Exon (19)3127..3225
Gene:ABCA3
Gene Synonym:
Exon (20)3226..3412
Gene:ABCA3
Gene Synonym:
Exon (21)3413..3716
Gene:ABCA3
Gene Synonym:
Exon (22)3717..3990
Gene:ABCA3
Gene Synonym:
Exon (23)3991..4195
Gene:ABCA3
Gene Synonym:
Exon (24)4196..4415
Gene:ABCA3
Gene Synonym:
Exon (25)4416..4574
Gene:ABCA3
Gene Synonym:
Exon (26)4575..4747
Gene:ABCA3
Gene Synonym:
Exon (27)4748..4876
Gene:ABCA3
Gene Synonym:
Exon (28)4877..5071
Gene:ABCA3
Gene Synonym:
Exon (29)5072..5259
Gene:ABCA3
Gene Synonym:
Exon (30)5260..5430
Gene:ABCA3
Gene Synonym:
Exon (31)5431..5621
Gene:ABCA3
Gene Synonym:
Exon (32)5622..5695
Gene:ABCA3
Gene Synonym:
Exon (33)5696..6623
Gene:ABCA3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001089
Organism Homo sapiens (human)
Definition Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 3 (ABCA3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001089

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
ATGGCTGTGC TCAGGCAGCT GGCGCTCCTC CTCTGGAAGA ACTACACCCT GCAGAAGCGG 
AAGGTCCTGG TGACGGTCCT GGAACTCTTC CTGCCATTGC TGTTTTCTGG GATCCTCATC
TGGCTCCGCT TGAAGATTCA GTCGGAAAAT GTGCCCAACG CCACCATCTA CCCGGGCCAG
TCCATCCAGG AGCTGCCTCT GTTCTTCACC TTCCCTCCGC CAGGAGACAC CTGGGAGCTT
GCCTACATCC CTTCTCACAG TGACGCTGCC AAGACCGTCA CTGAGACAGT GCGCAGGGCA
CTTGTGATCA ACATGCGAGT GCGCGGCTTT CCCTCCGAGA AGGACTTTGA GGACTACATT
AGGTACGACA ACTGCTCGTC CAGCGTGCTG GCCGCCGTGG TCTTCGAGCA CCCCTTCAAC
CACAGCAAGG AGCCCCTGCC GCTGGCGGTG AAATATCACC TACGGTTCAG TTACACACGG
AGAAATTACA TGTGGACCCA AACAGGCTCC TTTTTCCTGA AAGAGACAGA AGGCTGGCAC
ACTACTTCCC TTTTCCCGCT TTTCCCAAAC CCAGGACCAA GGGAACCTAC ATCCCCTGAT
GGCGGAGAAC CTGGGTACAT CCGGGAAGGC TTCCTGGCCG TGCAGCATGC TGTGGACCGG
GCCATCATGG AGTACCATGC CGATGCCGCC ACACGCCAGC TGTTCCAGAG ACTGACGGTG
ACCATCAAGA GGTTCCCGTA CCCGCCGTTC ATCGCAGACC CCTTCCTCGT GGCCATCCAG
TACCAGCTGC CCCTGCTGCT GCTGCTCAGC TTCACCTACA CCGCGCTCAC CATTGCCCGT
GCTGTCGTGC AGGAGAAGGA AAGGAGGCTG AAGGAGTACA TGCGCATGAT GGGGCTCAGC
AGCTGGCTGC ACTGGAGTGC CTGGTTCCTC TTGTTCTTCC TCTTCCTCCT CATCGCCGCC
TCCTTCATGA CCCTGCTCTT CTGTGTCAAG GTGAAGCCAA ATGTAGCCGT GCTGTCCCGC
AGCGACCCCT CCCTGGTGCT CGCCTTCCTG CTGTGCTTCG CCATCTCTAC CATCTCCTTC
AGCTTCATGG TCAGCACCTT CTTCAGCAAA GCCAACATGG CAGCAGCCTT CGGAGGCTTC
CTCTACTTCT TCACCTACAT CCCCTACTTC TTCGTGGCCC CTCGGTACAA CTGGATGACT
CTGAGCCAGA AGCTCTGCTC CTGCCTCCTG TCTAATGTCG CCATGGCAAT GGGAGCCCAG
CTCATTGGGA AATTTGAGGC GAAAGGCATG GGCATCCAGT GGCGAGACCT CCTGAGTCCC
GTCAACGTGG ACGACGACTT CTGCTTCGGG CAGGTGCTGG GGATGCTGCT GCTGGACTCT
GTGCTCTATG GCCTGGTGAC CTGGTACATG GAGGCCGTCT TCCCAGGGCA GTTCGGCGTG
CCTCAGCCCT GGTACTTCTT CATCATGCCC TCCTATTGGT GTGGGAAGCC AAGGGCGGTT
GCAGGGAAGG AGGAAGAAGA CAGTGACCCC GAGAAAGCAC TCAGAAACGA GTACTTTGAA
GCCGAGCCAG AGGACCTGGT GGCGGGGATC AAGATCAAGC ACCTGTCCAA GGTGTTCAGG
GTGGGAAATA AGGACAGGGC GGCCGTCAGA GACCTGAACC TCAACCTGTA CGAGGGACAG
ATCACCGTCC TGCTGGGCCA CAACGGTGCC GGGAAGACCA CCACCCTCTC CATGCTCACA
GGTCTCTTTC CCCCCACCAG TGGACGGGCA TACATCAGCG GGTATGAAAT TTCCCAGGAC
ATGGTTCAGA TCCGGAAGAG CCTGGGCCTG TGCCCGCAGC ACGACATCCT GTTTGACAAC
TTGACAGTCG CAGAGCACCT TTATTTCTAC GCCCAGCTGA AGGGCCTGTC ACGTCAGAAG
TGCCCTGAAG AAGTCAAGCA GATGCTGCAC ATCATCGGCC TGGAGGACAA GTGGAACTCA
CGGAGCCGCT TCCTGAGCGG GGGCATGAGG CGCAAGCTCT CCATCGGCAT CGCCCTCATC
GCAGGCTCCA AGGTGCTGAT ACTGGACGAG CCCACCTCGG GCATGGACGC CATCTCCAGG
AGGGCCATCT GGGATCTTCT TCAGCGGCAG AAAAGTGACC GCACCATCGT GCTGACCACC
CACTTCATGG ACGAGGCTGA CCTGCTGGGA GACCGCATCG CCATCATGGC CAAGGGGGAG
CTGCAGTGCT GCGGGTCCTC GCTGTTCCTC AAGCAGAAAT ACGGTGCCGG CTATCACATG
ACGCTGGTGA AGGAGCCGCA CTGCAACCCG GAAGACATCT CCCAGCTGGT CCACCACCAC
GTGCCCAACG CCACGCTGGA GAGCAGCGCT GGGGCCGAGC TGTCTTTCAT CCTTCCCAGA
GAGAGCACGC ACAGGTTTGA AGGTCTCTTT GCTAAACTGG AGAAGAAGCA GAAAGAGCTG
GGCATTGCCA GCTTTGGGGC ATCCATCACC ACCATGGAGG AAGTCTTCCT TCGGGTCGGG
AAGCTGGTGG ACAGCAGTAT GGACATCCAG GCCATCCAGC TCCCTGCCCT GCAGTACCAG
CACGAGAGGC GCGCCAGCGA CTGGGCTGTG GACAGCAACC TCTGTGGGGC CATGGACCCC
TCCGACGGCA TTGGAGCCCT CATCGAGGAG GAGCGCACCG CTGTCAAGCT CAACACTGGG
CTCGCCCTGC ACTGCCAGCA ATTCTGGGCC ATGTTCCTGA AGAAGGCCGC ATACAGCTGG
CGCGAGTGGA AAATGGTGGC GGCACAGGTC CTGGTGCCTC TGACCTGCGT CACCCTGGCC
CTCCTGGCCA TCAACTACTC CTCGGAGCTC TTCGACGACC CCATGCTGAG GCTGACCTTG
GGCGAGTACG GCAGAACCGT CGTGCCCTTC TCAGTTCCCG GGACCTCCCA GCTGGGTCAG
CAGCTGTCAG AGCATCTGAA AGACGCACTG CAGGCTGAGG GACAGGAGCC CCGCGAGGTG
CTCGGTGACC TGGAGGAGTT CTTGATCTTC AGGGCTTCTG TGGAGGGGGG CGGCTTTAAT
GAGCGGTGCC TTGTGGCAGC GTCCTTCAGA GATGTGGGAG AGCGCACGGT CGTCAACGCC
TTGTTCAACA ACCAGGCGTA CCACTCTCCA GCCACTGCCC TGGCCGTCGT GGACAACCTT
CTGTTCAAGC TGCTGTGCGG GCCTCACGCC TCCATTGTGG TCTCCAACTT CCCCCAGCCC
CGGAGCGCCC TGCAGGCTGC CAAGGACCAG TTTAACGAGG GCCGGAAGGG ATTCGACATT
GCCCTCAACC TGCTCTTCGC CATGGCATTC TTGGCCAGCA CGTTCTCCAT CCTGGCGGTC
AGCGAGAGGG CCGTGCAGGC CAAGCATGTG CAGTTTGTGA GTGGAGTCCA CGTGGCCAGT
TTCTGGCTCT CTGCTCTGCT GTGGGACCTC ATCTCCTTCC TCATCCCCAG TCTGCTGCTG
CTGGTGGTGT TTAAGGCCTT CGACGTGCGT GCCTTCACGC GGGACGGCCA CATGGCTGAC
ACCCTGCTGC TGCTCCTGCT CTACGGCTGG GCCATCATCC CCCTCATGTA CCTGATGAAC
TTCTTCTTCT TGGGGGCGGC CACTGCCTAC ACGAGGCTGA CCATCTTCAA CATCCTGTCA
GGCATCGCCA CCTTCCTGAT GGTCACCATC ATGCGCATCC CAGCTGTAAA ACTGGAAGAA
CTTTCCAAAA CCCTGGATCA CGTGTTCCTG GTGCTGCCCA ACCACTGTCT GGGGATGGCA
GTCAGCAGTT TCTACGAGAA CTACGAGACG CGGAGGTACT GCACCTCCTC CGAGGTCGCC
GCCCACTACT GCAAGAAATA TAACATCCAG TACCAGGAGA ACTTCTATGC CTGGAGCGCC
CCGGGGGTCG GCCGGTTTGT GGCCTCCATG GCCGCCTCAG GGTGCGCCTA CCTCATCCTG
CTCTTCCTCA TCGAGACCAA CCTGCTTCAG AGACTCAGGG GCATCCTCTG CGCCCTCCGG
AGGAGGCGGA CACTGACAGA ATTATACACC CGGATGCCTG TGCTTCCTGA GGACCAAGAT
GTAGCGGACG AGAGGACCCG CATCCTGGCC CCCAGCCCGG ACTCCCTGCT CCACACACCT
CTGATTATCA AGGAGCTCTC CAAGGTGTAC GAGCAGCGGG TGCCCCTCCT GGCCGTGGAC
AGGCTCTCCC TCGCGGTGCA GAAAGGGGAG TGCTTCGGCC TGCTGGGCTT CAATGGAGCC
GGGAAGACCA CGACTTTCAA AATGCTGACC GGGGAGGAGA GCCTCACTTC TGGGGATGCC
TTTGTCGGGG GTCACAGAAT CAGCTCTGAT GTCGGAAAGG TGCGGCAGCG GATCGGCTAC
TGCCCGCAGT TTGATGCCTT GCTGGACCAC ATGACAGGCC GGGAGATGCT GGTCATGTAC
GCTCGGCTCC GGGGCATCCC TGAGCGCCAC ATCGGGGCCT GCGTGGAGAA CACTCTGCGG
GGCCTGCTGC TGGAGCCACA TGCCAACAAG CTGGTCAGGA CGTACAGTGG TGGTAACAAG
CGGAAGCTGA GCACCGGCAT CGCCCTGATC GGAGAGCCTG CTGTCATCTT CCTGGACGAG
CCGTCCACTG GCATGGACCC CGTGGCCCGG CGCCTGCTTT GGGACACCGT GGCACGAGCC
CGAGAGTCTG GCAAGGCCAT CATCATCACC TCCCACAGCA TGGAGGAGTG TGAGGCCCTG
TGCACCCGGC TGGCCATCAT GGTGCAGGGG CAGTTCAAGT GCCTGGGCAG CCCCCAGCAC
CTCAAGAGCA AGTTCGGCAG CGGCTACTCC CTGCGGGCCA AGGTGCAGAG TGAAGGGCAA
CAGGAGGCGC TGGAGGAGTT CAAGGCCTTC GTGGACCTGA CCTTTCCAGG CAGCGTCCTG
GAAGATGAGC ACCAAGGCAT GGTCCATTAC CACCTGCCGG GCCGTGACCT CAGCTGGGCG
AAGGTTTTCG GTATTCTGGA GAAAGCCAAG GAAAAGTACG GCGTGGACGA CTACTCCGTG
AGCCAGATCT CGCTGGAACA GGTCTTCCTG AGCTTCGCCC ACCTGCAGCC GCCCACCGCA
GAGGAGGGGC GATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Novel mutation in ABCA3 resulting in fatal congenital surfactant deficiency in two siblings
Am. J. Respir. Crit. Care Med. 189 (6), 750-752 (2014)
Moore GP, Lines MA, Geraghty MT, de Nanassy J and Kovesi T.


book

Novel ABCA3 mutations as a cause of respiratory distress in a term newborn
Gene 534 (2), 417-420 (2014)
Goncalves JP, Pinheiro L, Costa M, Silva A, Goncalves A and Pereira A.


book

Disruption of N-linked glycosylation promotes proteasomal degradation of the human ATP-binding cassette transporter ABCA3
Am. J. Physiol. Lung Cell Mol. Physiol. 305 (12), L970-L980 (2013)
Beers MF, Zhao M, Tomer Y, Russo SJ, Zhang P, Gonzales LW, Guttentag SH and Mulugeta S.


book

Interstitial lung disease in two brothers with novel compound heterozygous ABCA3 mutations
Eur. J. Pediatr. 172 (7), 953-957 (2013)
Kitazawa H, Moriya K, Niizuma H, Kawano K, Saito-Nanjo Y, Uchiyama T, Rikiishi T, Sasahara Y, Sakamoto O, Setoguchi Y and Kure S.


book

Tyrosinekinase inhibition facilitates cooperation of transcription factor SALL4 and ABC transporter A3 towards intrinsic CML cell drug resistance
Br. J. Haematol. 161 (2), 204-213 (2013)
Hupfeld T, Chapuy B, Schrader V, Beutler M, Veltkamp C, Koch R, Cameron S, Aung T, Haase D, Larosee P, Truemper L and Wulf GG.


book

ABCA3 gene mutations in newborns with fatal surfactant deficiency
N. Engl. J. Med. 350 (13), 1296-1303 (2004)
Shulenin S, Nogee LM, Annilo T, Wert SE, Whitsett JA and Dean M.


book

Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter protein ABCA3
J. Biol. Chem. 277 (25), 22147-22155 (2002)
Mulugeta S, Gray JM, Notarfrancesco KL, Gonzales LW, Koval M, Feinstein SI, Ballard PL, Fisher AB and Shuman H.


book

ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells
FEBS Lett. 508 (2), 221-225 (2001)
Yamano G, Funahashi H, Kawanami O, Zhao LX, Ban N, Uchida Y, Morohoshi T, Ogawa J, Shioda S and Inagaki N.


book

The cloning of a human ABC gene (ABC3) mapping to chromosome 16p13.3
Genomics 39 (2), 231-234 (1997)
Connors TD, Van Raay TJ, Petry LR, Klinger KW, Landes GM and Burn TC.


book

Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance-associated protein
FEBS Lett. 391 (1-2), 61-65 (1996)
Klugbauer N and Hofmann F.


 
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