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ESR2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol ESR2
Entrez Gene ID 2100
Full Name estrogen receptor 2 (ER beta)
Synonyms ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
General protein information
Preferred Names
estrogen receptor beta
Names
estrogen receptor beta
estrogen receptor beta 4
estrogen nuclear receptor beta variant a
estrogen nuclear receptor beta variant b
nuclear receptor subfamily 3 group A member 2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q23.2

Summary This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

601663


mRNA and Protein(s)

mRNA Protein Name
XM_011536545 XP_011534847 estrogen receptor beta isoform X2
XM_011536546 XP_011534848 estrogen receptor beta isoform X1
NM_001214902 NP_001201831 estrogen receptor beta isoform 3
NM_001271876 NP_001258805 estrogen receptor beta isoform 5
NM_001271877 NP_001258806 estrogen receptor beta isoform 6
NM_001291712 NP_001278641 estrogen receptor beta isoform 2
NM_001437 NP_001428 estrogen receptor beta isoform 1
NM_001040275 NP_001035365 estrogen receptor beta isoform 2
NM_001291723 NP_001278652 estrogen receptor beta isoform 2



Homo sapiens (human) ESR2 NP_001428.1
Pan troglodytes (chimpanzee) ESR2 XP_001170310.1
Macaca mulatta (Rhesus monkey) ESR2 XP_001101433.1
Canis lupus familiaris (dog) ESR2 XP_866134.3
Bos taurus (cattle) ESR2 NP_776476.2
Mus musculus (house mouse) Esr2 NP_034287.3
Rattus norvegicus (Norway rat) Esr2 NP_036886.1
Gallus gallus (chicken) ESR2 NP_990125.1
Danio rerio (zebrafish) esr2a NP_851297.1
Danio rerio (zebrafish) esr2b NP_777287.2
Xenopus (Silurana) tropicalis (western clawed frog) esr2 NP_001035101.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ESR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ESR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu57581 XM_011536545 PREDICTED: Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu25562
XM_011536546 PREDICTED: Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
OHu22338 NM_001214902 Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant d, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu22461 NM_001271876 Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant f, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu23139 NM_001271877 Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant g, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu23506
NM_001291712 Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant k, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu25562
NM_001437 Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant a, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
OHu23506
NM_001040275 Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant b, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu23506
NM_001291723 Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant l, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu57581
Clone ID Related Accession (Same CDS sequence) XM_011536545
Accession Version XM_011536545.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1623bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product estrogen receptor beta isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGAGA CAAAGTGTGG GCATTTTTCC AAAATGGGAG
CTGATAAACA TCAACAGAGC ATCACTAATT TACAAAGGCA TTTCTGAGAA GCCTGAAGAT
CACCCATACC CAAAGGAGGA AAGCCAAATG CACCCTCAGG AGCAGCACAC AAATAAGAGA
AACAGCAACT GGACCACAGG CACTCCACGT GCATCTCTCC AACATATTGT GCTGCGCAAA
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011534847.1
CDS538..2160
Misc Feature(1)598..909(+)
Misc Feature(2)967..1212(+)
Misc Feature(3)982..1149(+)
Misc Feature(4)1009..1152(+)
Misc Feature(5)1087..1137(+)
Misc Feature(6)1324..1941(+)
Misc Feature(7)1429..1575(+)
Misc Feature(8)1465..1533(+)
Misc Feature(9)1744..1938(+)
Translation

Target ORF information:

RefSeq Version XM_011536545
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011536545

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGAGA CAAAGTGTGG GCATTTTTCC AAAATGGGAG
CTGATAAACA TCAACAGAGC ATCACTAATT TACAAAGGCA TTTCTGAGAA GCCTGAAGAT
CACCCATACC CAAAGGAGGA AAGCCAAATG CACCCTCAGG AGCAGCACAC AAATAAGAGA
AACAGCAACT GGACCACAGG CACTCCACGT GCATCTCTCC AACATATTGT GCTGCGCAAA
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25562
Clone ID Related Accession (Same CDS sequence) NM_001437 , XM_011536546
Accession Version XM_011536546.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1593bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product estrogen receptor beta isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGTAAC AAGGGCATGG AACATCTGCT CAACATGAAG
TGCAAAAATG TGGTCCCAGT GTATGACCTG CTGCTGGAGA TGCTGAATGC CCACGTGCTT
CGCGGGTGCA AGTCCTCCAT CACGGGGTCC GAGTGCAGCC CGGCAGAGGA CAGTAAAAGC
AAAGAGGGCT CCCAGAACCC ACAGTCTCAG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011534848.1
CDS1039..2631
Misc Feature(1)1099..1410(+)
Misc Feature(2)1468..1713(+)
Misc Feature(3)1483..1650(+)
Misc Feature(4)1510..1653(+)
Misc Feature(5)1588..1638(+)
Misc Feature(6)1825..2532(+)
Misc Feature(7)1930..2463(+)
Misc Feature(8)1966..2520(+)
Misc Feature(9)2245..2448(+)
Translation

Target ORF information:

RefSeq Version XM_011536546
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011536546

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGTAAC AAGGGCATGG AACATCTGCT CAACATGAAG
TGCAAAAATG TGGTCCCAGT GTATGACCTG CTGCTGGAGA TGCTGAATGC CCACGTGCTT
CGCGGGTGCA AGTCCTCCAT CACGGGGTCC GAGTGCAGCC CGGCAGAGGA CAGTAAAAGC
AAAGAGGGCT CCCAGAACCC ACAGTCTCAG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22338
Clone ID Related Accession (Same CDS sequence) NM_001214902
Accession Version NM_001214902.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1446bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product estrogen receptor beta isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB006590.1, DQ838582.1, AL355094.3 and BC024181.2. Transcript Variant: This variant (d) differs in the 3' UTR and 3' coding sequence, compared to variant a. The resulting isoform (3, also known as ER-beta4) has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ838582.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGATGG GGAGAAAAGC AATTCATTCA TTTGAAGTTA
TCTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001201831.1
CDS91..1536
Misc Feature(1)25..27(+)
Misc Feature(2)151..462(+)
Misc Feature(3)520..765(+)
Misc Feature(4)535..702(+)
Misc Feature(5)562..705(+)
Misc Feature(6)640..690(+)
Misc Feature(7)877..1494(+)
Misc Feature(8)982..1128(+)
Misc Feature(9)1018..1086(+)
Misc Feature(10)1297..1491(+)
Exon (1)1..452
Gene:ESR2
Gene Synonym:
Exon (2)453..625
Gene:ESR2
Gene Synonym:
Exon (3)626..742
Gene:ESR2
Gene Synonym:
Exon (4)743..1042
Gene:ESR2
Gene Synonym:
Exon (5)1043..1181
Gene:ESR2
Gene Synonym:
Exon (6)1182..1315
Gene:ESR2
Gene Synonym:
Exon (7)1316..1496
Gene:ESR2
Gene Synonym:
Exon (8)1497..2393
Gene:ESR2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001214902
Organism Homo sapiens (human)
Definition Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant d, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001214902

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGATGG GGAGAAAAGC AATTCATTCA TTTGAAGTTA
TCTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22461
Clone ID Related Accession (Same CDS sequence) NM_001271876
Accession Version NM_001271876.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1425bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product estrogen receptor beta isoform 5
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB006590.1, DQ777076.1 and AL355094.3. Transcript Variant: This variant (f) differs in the 3' UTR and 3' coding sequence, compared to variant a. The resulting isoform (5, also known as ER-beta4) has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ777076.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGTCC TGTGTATACA AGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001258805.1
CDS91..1515
Misc Feature(1)25..27(+)
Misc Feature(2)91..534(+)
Misc Feature(3)151..462(+)
Misc Feature(4)349..351(+)
Misc Feature(5)403..405(+)
Misc Feature(6)520..765(+)
Misc Feature(7)535..702(+)
Misc Feature(8)562..705(+)
Misc Feature(9)640..690(+)
Misc Feature(10)877..1500(+)
Misc Feature(11)982..1128(+)
Misc Feature(12)1018..1086(+)
Misc Feature(13)1297..1500(+)
Exon (1)1..452
Gene:ESR2
Gene Synonym:
Exon (2)453..625
Gene:ESR2
Gene Synonym:
Exon (3)626..742
Gene:ESR2
Gene Synonym:
Exon (4)743..1042
Gene:ESR2
Gene Synonym:
Exon (5)1043..1181
Gene:ESR2
Gene Synonym:
Exon (6)1182..1315
Gene:ESR2
Gene Synonym:
Exon (7)1316..1496
Gene:ESR2
Gene Synonym:
Exon (8)1497..1724
Gene:ESR2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001271876
Organism Homo sapiens (human)
Definition Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant f, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001271876

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGTCC TGTGTATACA AGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23139
Clone ID Related Accession (Same CDS sequence) NM_001271877
Accession Version NM_001271877.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1320bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product estrogen receptor beta isoform 6
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB006590.1, AF074599.1 and AL161756.6. Transcript Variant: This variant (g) lacks two consecutive exons in the coding region compared to variant a. The resulting isoform (6, also known as 5/6) lacks an internal segment compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF074599.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGTATGTAC
CCTCTGGTCA CAGCGACCCA GGATGCTGAC AGCAGCCGGA AGCTGGCTCA CTTGCTGAAC
GCCGTGACCG ATGCTTTGGT TTGGGTGATT GCCAAGAGCG GCATCTCCTC CCAGCAGCAA
TCCATGCGCC TGGCTAACCT CCTGATGCTC CTGTCCCACG TCAGGCATGC GAGTAACAAG
GGCATGGAAC ATCTGCTCAA CATGAAGTGC AAAAATGTGG TCCCAGTGTA TGACCTGCTG
CTGGAGATGC TGAATGCCCA CGTGCTTCGC GGGTGCAAGT CCTCCATCAC GGGGTCCGAG
TGCAGCCCGG CAGAGGACAG TAAAAGCAAA GAGGGCTCCC AGAACCCACA GTCTCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001258806.1
CDS91..1410
Misc Feature(1)25..27(+)
Misc Feature(2)151..462(+)
Misc Feature(3)520..765(+)
Misc Feature(4)535..702(+)
Misc Feature(5)562..705(+)
Misc Feature(6)640..690(+)
Misc Feature(7)877..1311(+)
Exon (1)1..452
Gene:ESR2
Gene Synonym:
Exon (2)453..625
Gene:ESR2
Gene Synonym:
Exon (3)626..742
Gene:ESR2
Gene Synonym:
Exon (4)743..1042
Gene:ESR2
Gene Synonym:
Exon (5)1043..1223
Gene:ESR2
Gene Synonym:
Exon (6)1224..1518
Gene:ESR2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001271877
Organism Homo sapiens (human)
Definition Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant g, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001271877

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGTATGTAC
CCTCTGGTCA CAGCGACCCA GGATGCTGAC AGCAGCCGGA AGCTGGCTCA CTTGCTGAAC
GCCGTGACCG ATGCTTTGGT TTGGGTGATT GCCAAGAGCG GCATCTCCTC CCAGCAGCAA
TCCATGCGCC TGGCTAACCT CCTGATGCTC CTGTCCCACG TCAGGCATGC GAGTAACAAG
GGCATGGAAC ATCTGCTCAA CATGAAGTGC AAAAATGTGG TCCCAGTGTA TGACCTGCTG
CTGGAGATGC TGAATGCCCA CGTGCTTCGC GGGTGCAAGT CCTCCATCAC GGGGTCCGAG
TGCAGCCCGG CAGAGGACAG TAAAAGCAAA GAGGGCTCCC AGAACCCACA GTCTCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23506
Clone ID Related Accession (Same CDS sequence) NM_001040275 , NM_001291712 , NM_001291723
Accession Version NM_001291712.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1488bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product estrogen receptor beta isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN366005.1, AB006589.1, KC777386.1, AK292370.1 and BC024181.2. On Apr 25, 2014 this sequence version replaced gi:578825587. Transcript Variant: This variant (k) represents an alternative promoter usage and differs in the 5' UTR, 3' coding region and 3' UTR, compared to variant a. The resulting isoform (2) has a distinct and shorter C-terminus, compared to isoform 1. Variants b, k and m encode the same isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB006589.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGGCA GAAAAGGCCT CTCAAACACT CACCTCATTT
GGAATGAAGA TGGAGACTCT TTTGCCTGAA GCAACGATGG AGCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278641.1
CDS1729..3216
Misc Feature(1)1663..1665(+)
Misc Feature(2)1789..2100(+)
Misc Feature(3)2158..2403(+)
Misc Feature(4)2173..2340(+)
Misc Feature(5)2200..2343(+)
Misc Feature(6)2278..2328(+)
Misc Feature(7)2515..3195(+)
Misc Feature(8)2620..3156(+)
Misc Feature(9)2656..2724(+)
Misc Feature(10)2935..3138(+)
Exon (1)1..653
Gene:ESR2
Gene Synonym:
Exon (2)654..961
Gene:ESR2
Gene Synonym:
Exon (3)962..1145
Gene:ESR2
Gene Synonym:
Exon (4)1146..1358
Gene:ESR2
Gene Synonym:
Exon (5)1359..1452
Gene:ESR2
Gene Synonym:
Exon (6)1453..1638
Gene:ESR2
Gene Synonym:
Exon (7)1639..2090
Gene:ESR2
Gene Synonym:
Exon (8)2091..2263
Gene:ESR2
Gene Synonym:
Exon (9)2264..2380
Gene:ESR2
Gene Synonym:
Exon (10)2381..2680
Gene:ESR2
Gene Synonym:
Exon (11)2681..2819
Gene:ESR2
Gene Synonym:
Exon (12)2820..2953
Gene:ESR2
Gene Synonym:
Exon (13)2954..3134
Gene:ESR2
Gene Synonym:
Exon (14)3135..4037
Gene:ESR2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291712
Organism Homo sapiens (human)
Definition Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant k, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291712

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGGCA GAAAAGGCCT CTCAAACACT CACCTCATTT
GGAATGAAGA TGGAGACTCT TTTGCCTGAA GCAACGATGG AGCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25562
Clone ID Related Accession (Same CDS sequence) NM_001437 , XM_011536546
Accession Version NM_001437.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1593bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product estrogen receptor beta isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF060555.1, AF051427.1 and AL161756.6. On May 4, 2006 this sequence version replaced gi:10835012. Transcript Variant: This variant (a, also known as 1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## regulatory uORF :: PMID: 20920096 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: AF051427.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 5' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGTAAC AAGGGCATGG AACATCTGCT CAACATGAAG
TGCAAAAATG TGGTCCCAGT GTATGACCTG CTGCTGGAGA TGCTGAATGC CCACGTGCTT
CGCGGGTGCA AGTCCTCCAT CACGGGGTCC GAGTGCAGCC CGGCAGAGGA CAGTAAAAGC
AAAGAGGGCT CCCAGAACCC ACAGTCTCAG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001428.1
CDS469..2061
Misc Feature(1)1..1(+)
Misc Feature(2)64..64(+)
Misc Feature(3)287..287(+)
Misc Feature(4)318..347(+)
Misc Feature(5)403..405(+)
Misc Feature(6)416..478(+)
Misc Feature(7)469..912(+)
Misc Feature(8)529..840(+)
Misc Feature(9)727..729(+)
Misc Feature(10)781..783(+)
Misc Feature(11)898..1143(+)
Misc Feature(12)913..1080(+)
Misc Feature(13)940..1083(+)
Misc Feature(14)1018..1068(+)
Misc Feature(15)1111..2058(+)
Misc Feature(16)1255..1962(+)
Misc Feature(17)1360..1893(+)
Misc Feature(18)1396..1950(+)
Misc Feature(19)1675..1878(+)
Exon (1)1..378
Gene:ESR2
Gene Synonym:
Exon (2)379..830
Gene:ESR2
Gene Synonym:
Exon (3)831..1003
Gene:ESR2
Gene Synonym:
Exon (4)1004..1120
Gene:ESR2
Gene Synonym:
Exon (5)1121..1420
Gene:ESR2
Gene Synonym:
Exon (6)1421..1559
Gene:ESR2
Gene Synonym:
Exon (7)1560..1693
Gene:ESR2
Gene Synonym:
Exon (8)1694..1874
Gene:ESR2
Gene Synonym:
Exon (9)1875..2169
Gene:ESR2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001437
Organism Homo sapiens (human)
Definition Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant a, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001437

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGTAAC AAGGGCATGG AACATCTGCT CAACATGAAG
TGCAAAAATG TGGTCCCAGT GTATGACCTG CTGCTGGAGA TGCTGAATGC CCACGTGCTT
CGCGGGTGCA AGTCCTCCAT CACGGGGTCC GAGTGCAGCC CGGCAGAGGA CAGTAAAAGC
AAAGAGGGCT CCCAGAACCC ACAGTCTCAG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23506
Clone ID Related Accession (Same CDS sequence) NM_001040275 , NM_001291712 , NM_001291723
Accession Version NM_001040275.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1488bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product estrogen receptor beta isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF060555.1, AF051428.1, AL355094.3 and BC024181.2. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (b, also known as 2) differs in the 3' UTR and 3' coding sequence, compared to variant a. The resulting isoform (2) has a distinct and shorter C-terminus, compared to isoform 1, and dominantly inhibits the activity of other estrogen receptor family members. Variants b, k and m encode the same isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## regulatory uORF :: PMID: 20920096 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: AF051428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGGCA GAAAAGGCCT CTCAAACACT CACCTCATTT
GGAATGAAGA TGGAGACTCT TTTGCCTGAA GCAACGATGG AGCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001035365.1
CDS469..1956
Misc Feature(1)1..1(+)
Misc Feature(2)64..64(+)
Misc Feature(3)287..287(+)
Misc Feature(4)318..347(+)
Misc Feature(5)403..405(+)
Misc Feature(6)416..478(+)
Misc Feature(7)529..840(+)
Misc Feature(8)898..1143(+)
Misc Feature(9)913..1080(+)
Misc Feature(10)940..1083(+)
Misc Feature(11)1018..1068(+)
Misc Feature(12)1255..1935(+)
Misc Feature(13)1360..1896(+)
Misc Feature(14)1396..1464(+)
Misc Feature(15)1675..1878(+)
Exon (1)1..378
Gene:ESR2
Gene Synonym:
Exon (2)379..830
Gene:ESR2
Gene Synonym:
Exon (3)831..1003
Gene:ESR2
Gene Synonym:
Exon (4)1004..1120
Gene:ESR2
Gene Synonym:
Exon (5)1121..1420
Gene:ESR2
Gene Synonym:
Exon (6)1421..1559
Gene:ESR2
Gene Synonym:
Exon (7)1560..1693
Gene:ESR2
Gene Synonym:
Exon (8)1694..1874
Gene:ESR2
Gene Synonym:
Exon (9)1875..2456
Gene:ESR2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001040275
Organism Homo sapiens (human)
Definition Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant b, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001040275

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGGCA GAAAAGGCCT CTCAAACACT CACCTCATTT
GGAATGAAGA TGGAGACTCT TTTGCCTGAA GCAACGATGG AGCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23506
Clone ID Related Accession (Same CDS sequence) NM_001040275 , NM_001291712 , NM_001291723
Accession Version NM_001291723.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1488bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product estrogen receptor beta isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN366005.1, BC024181.2, AK292370.1 and BX094834.1. On Apr 25, 2014 this sequence version replaced gi:428673605. Transcript Variant: This variant (l) represents an alternative promoter usage and differs in the 5' UTR, 3' coding region and 3' UTR, compared to variant a. The resulting isoform (2) has a distinct and shorter C-terminus, compared to isoform 1. Variants b, k and m encode the same isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK292370.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 23806560 ##RefSeq-Attributes-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGGCA GAAAAGGCCT CTCAAACACT CACCTCATTT
GGAATGAAGA TGGAGACTCT TTTGCCTGAA GCAACGATGG AGCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278652.1
CDS744..2231
Misc Feature(1)30..434(+)
Misc Feature(2)80..205(+)
Misc Feature(3)440..574(+)
Misc Feature(4)506..574(+)
Misc Feature(5)550..582(+)
Misc Feature(6)588..680(+)
Misc Feature(7)592..651(+)
Misc Feature(8)642..680(+)
Misc Feature(9)678..680(+)
Misc Feature(10)691..753(+)
Misc Feature(11)804..1115(+)
Misc Feature(12)1173..1418(+)
Misc Feature(13)1188..1355(+)
Misc Feature(14)1215..1358(+)
Misc Feature(15)1293..1343(+)
Misc Feature(16)1530..2210(+)
Misc Feature(17)1635..2171(+)
Misc Feature(18)1671..1739(+)
Misc Feature(19)1950..2153(+)
Exon (1)1..653
Gene:ESR2
Gene Synonym:
Exon (2)654..1105
Gene:ESR2
Gene Synonym:
Exon (3)1106..1278
Gene:ESR2
Gene Synonym:
Exon (4)1279..1395
Gene:ESR2
Gene Synonym:
Exon (5)1396..1695
Gene:ESR2
Gene Synonym:
Exon (6)1696..1834
Gene:ESR2
Gene Synonym:
Exon (7)1835..1968
Gene:ESR2
Gene Synonym:
Exon (8)1969..2149
Gene:ESR2
Gene Synonym:
Exon (9)2150..2731
Gene:ESR2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291723
Organism Homo sapiens (human)
Definition Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant l, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291723

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGATATAA AAAACTCACC ATCTAGCCTT AATTCTCCTT CCTCCTACAA CTGCAGTCAA 
TCCATCTTAC CCCTGGAGCA CGGCTCCATA TACATACCTT CCTCCTATGT AGACAGCCAC
CATGAATATC CAGCCATGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG CATTCCCAGC
AATGTCACTA ACTTGGAAGG TGGGCCTGGT CGGCAGACCA CAAGCCCAAA TGTGTTGTGG
CCAACACCTG GGCACCTTTC TCCTTTAGTG GTCCATCGCC AGTTATCACA TCTGTATGCG
GAACCTCAAA AGAGTCCCTG GTGTGAAGCA AGATCGCTAG AACACACCTT ACCTGTAAAC
AGAGAGACAC TGAAAAGGAA GGTTAGTGGG AACCGTTGCG CCAGCCCTGT TACTGGTCCA
GGTTCAAAGA GGGATGCTCA CTTCTGCGCT GTCTGCAGCG ATTACGCATC GGGATATCAC
TATGGAGTCT GGTCGTGTGA AGGATGTAAG GCCTTTTTTA AAAGAAGCAT TCAAGGACAT
AATGATTATA TTTGTCCAGC TACAAATCAG TGTACAATCG ATAAAAACCG GCGCAAGAGC
TGCCAGGCCT GCCGACTTCG GAAGTGTTAC GAAGTGGGAA TGGTGAAGTG TGGCTCCCGG
AGAGAGAGAT GTGGGTACCG CCTTGTGCGG AGACAGAGAA GTGCCGACGA GCAGCTGCAC
TGTGCCGGCA AGGCCAAGAG AAGTGGCGGC CACGCGCCCC GAGTGCGGGA GCTGCTGCTG
GACGCCCTGA GCCCCGAGCA GCTAGTGCTC ACCCTCCTGG AGGCTGAGCC GCCCCATGTG
CTGATCAGCC GCCCCAGTGC GCCCTTCACC GAGGCCTCCA TGATGATGTC CCTGACCAAG
TTGGCCGACA AGGAGTTGGT ACACATGATC AGCTGGGCCA AGAAGATTCC CGGCTTTGTG
GAGCTCAGCC TGTTCGACCA AGTGCGGCTC TTGGAGAGCT GTTGGATGGA GGTGTTAATG
ATGGGGCTGA TGTGGCGCTC AATTGACCAC CCCGGCAAGC TCATCTTTGC TCCAGATCTT
GTTCTGGACA GGGATGAGGG GAAATGCGTA GAAGGAATTC TGGAAATCTT TGACATGCTC
CTGGCAACTA CTTCAAGGTT TCGAGAGTTA AAACTCCAAC ACAAAGAATA TCTCTGTGTC
AAGGCCATGA TCCTGCTCAA TTCCAGTATG TACCCTCTGG TCACAGCGAC CCAGGATGCT
GACAGCAGCC GGAAGCTGGC TCACTTGCTG AACGCCGTGA CCGATGCTTT GGTTTGGGTG
ATTGCCAAGA GCGGCATCTC CTCCCAGCAG CAATCCATGC GCCTGGCTAA CCTCCTGATG
CTCCTGTCCC ACGTCAGGCA TGCGAGGGCA GAAAAGGCCT CTCAAACACT CACCTCATTT
GGAATGAAGA TGGAGACTCT TTTGCCTGAA GCAACGATGG AGCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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