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EVX1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol EVX1
Entrez Gene ID 2128
Full Name even-skipped homeobox 1
Synonyms EVX-1
General protein information
Preferred Names
homeobox even-skipped homolog protein 1
Names
homeobox even-skipped homolog protein 1
EVX-1
eve, even-skipped homeobox homolog 1
eve, even-skipped homeo box homolog 1
even-skipped homeo box 1 (homolog of Drosophila)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7p15.2

Summary This gene encodes a member of the even-skipped homeobox family characterized by the presence of a homeodomain closely related to the Drosophila even-skipped (eve) segmentation gene of the pair-rule class. The encoded protein may play an important role as a transcriptional repressor during embryogenesis. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

142996


mRNA and Protein(s)

mRNA Protein Name
NM_001304520 NP_001291449 homeobox even-skipped homolog protein 1 isoform 2
XM_011515173 XP_011513475 homeobox even-skipped homolog protein 1 isoform X1
NM_001989 NP_001980 homeobox even-skipped homolog protein 1 isoform 1
NM_001304519 NP_001291448 homeobox even-skipped homolog protein 1 isoform 2


Homo sapiens (human) EVX1 NP_001980.1
Pan troglodytes (chimpanzee) EVX1 XP_527702.1
Macaca mulatta (Rhesus monkey) EVX1 XP_001090913.1
Canis lupus familiaris (dog) EVX1 XP_539493.2
Bos taurus (cattle) EVX1 NP_001179310.1
Mus musculus (house mouse) Evx1 NP_031992.1
Rattus norvegicus (Norway rat) Evx1 NP_001178901.1
Rattus norvegicus (Norway rat) LOC100911889 XP_003752234.1
Gallus gallus (chicken) LOC100859345 XP_003640767.1
Gallus gallus (chicken) EVX1 XP_425994.2
Danio rerio (zebrafish) evx1 NP_571324.1
Xenopus (Silurana) tropicalis (western clawed frog) LOC100496893 XP_002933430.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following EVX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EVX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu41092 NM_001304520 Homo sapiens even-skipped homeobox 1 (EVX1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $139.30
$199.00
OHu41092 XM_011515173 PREDICTED: Homo sapiens even-skipped homeobox 1 (EVX1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $139.30
$199.00
OHu11389 NM_001989 Homo sapiens even-skipped homeobox 1 (EVX1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $237.30
$339.00
OHu41092 NM_001304519 Homo sapiens even-skipped homeobox 1 (EVX1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $139.30
$199.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu41092
Clone ID Related Accession (Same CDS sequence) NM_001304519 , NM_001304520 , XM_011515173
Accession Version NM_001304520.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 678bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 30-JAN-2015
Organism Homo sapiens (human)
Product homeobox even-skipped homolog protein 1 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK299188.1, AC004080.2, AK298822.1 and KF458418.1. On Jan 30, 2015 this sequence version replaced gi:578813328. Transcript Variant: This variant (3) uses an alternate splice site in the 5'-terminal exon, contains an alternate exon in its 5' UTR, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. Both variants 2 and 3 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK298822.1, DC366055.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGCGTCGTT ACCGCACCGC CTTCACCCGA GAGCAGATTG CGCGGCTGGA GAAGGAATTC 
TACCGGGAGA ACTACGTATC CAGGCCGCGG AGATGTGAGC TGGCGGCCGC CCTAAACCTG
CCGGAAACCA CCATCAAGGT GTGGTTCCAG AACCGGCGCA TGAAGGACAA GCGGCAGCGC
CTGGCCATGA CGTGGCCGCA CCCGGCGGAC CCCGCCTTCT ACACTTACAT GATGAGCCAT
GCGGCGGCCG CGGGCGGCCT GCCCTACCCC TTCCCATCGC ACCTGCCCCT GCCCTACTAC
TCGCCGGTGG GCCTGGGCGC CGCATCCGCC GCCTCCGCCG CCGCCTCGCC CTTCAGCGGC
TCGCTGCGCC CGCTCGACAC GTTCCGCGTG CTGTCGCAGC CCTACCCGCG GCCCGAACTG
CTGTGCGCCT TCCGCCACCC GCCGCTCTAC CCCGGGCCCG CGCACGGACT GGGCGCCTCT
GCCGGCGGCC CCTGCTCCTG CCTCGCCTGT CACAGCGGCC CGGCCAACGG GCTGGCGCCC
CGGGCTGCCG CCGCCTCGGA CTTCACCTGT GCCTCCACCT CCCGCTCGGA CTCCTTCCTC
ACCTTCGCGC CCTCGGTGCT CAGCAAGGCC TCCTCCGTCG CGCTGGACCA GAGGGAGGAG
GTGCCCCTCA CTAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001291449.1
CDS1030..1707
Misc Feature(1)907..909(+)
Misc Feature(2)1033..1209(+)
Misc Feature(3)1033..1203(+)
Misc Feature(4)1039..1191(+)
Exon (1)1..858
Gene:EVX1
Gene Synonym:
Exon (2)859..910
Gene:EVX1
Gene Synonym:
Exon (3)911..1167
Gene:EVX1
Gene Synonym:
Exon (4)1168..3101
Gene:EVX1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001304520
Organism Homo sapiens (human)
Definition Homo sapiens even-skipped homeobox 1 (EVX1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001304520

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGCGTCGTT ACCGCACCGC CTTCACCCGA GAGCAGATTG CGCGGCTGGA GAAGGAATTC 
TACCGGGAGA ACTACGTATC CAGGCCGCGG AGATGTGAGC TGGCGGCCGC CCTAAACCTG
CCGGAAACCA CCATCAAGGT GTGGTTCCAG AACCGGCGCA TGAAGGACAA GCGGCAGCGC
CTGGCCATGA CGTGGCCGCA CCCGGCGGAC CCCGCCTTCT ACACTTACAT GATGAGCCAT
GCGGCGGCCG CGGGCGGCCT GCCCTACCCC TTCCCATCGC ACCTGCCCCT GCCCTACTAC
TCGCCGGTGG GCCTGGGCGC CGCATCCGCC GCCTCCGCCG CCGCCTCGCC CTTCAGCGGC
TCGCTGCGCC CGCTCGACAC GTTCCGCGTG CTGTCGCAGC CCTACCCGCG GCCCGAACTG
CTGTGCGCCT TCCGCCACCC GCCGCTCTAC CCCGGGCCCG CGCACGGACT GGGCGCCTCT
GCCGGCGGCC CCTGCTCCTG CCTCGCCTGT CACAGCGGCC CGGCCAACGG GCTGGCGCCC
CGGGCTGCCG CCGCCTCGGA CTTCACCTGT GCCTCCACCT CCCGCTCGGA CTCCTTCCTC
ACCTTCGCGC CCTCGGTGCT CAGCAAGGCC TCCTCCGTCG CGCTGGACCA GAGGGAGGAG
GTGCCCCTCA CTAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu41092
Clone ID Related Accession (Same CDS sequence) NM_001304519 , NM_001304520 , XM_011515173
Accession Version XM_011515173.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 678bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product homeobox even-skipped homolog protein 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_007819.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
ATGCGTCGTT ACCGCACCGC CTTCACCCGA GAGCAGATTG CGCGGCTGGA GAAGGAATTC 
TACCGGGAGA ACTACGTATC CAGGCCGCGG AGATGTGAGC TGGCGGCCGC CCTAAACCTG
CCGGAAACCA CCATCAAGGT GTGGTTCCAG AACCGGCGCA TGAAGGACAA GCGGCAGCGC
CTGGCCATGA CGTGGCCGCA CCCGGCGGAC CCCGCCTTCT ACACTTACAT GATGAGCCAT
GCGGCGGCCG CGGGCGGCCT GCCCTACCCC TTCCCATCGC ACCTGCCCCT GCCCTACTAC
TCGCCGGTGG GCCTGGGCGC CGCATCCGCC GCCTCCGCCG CCGCCTCGCC CTTCAGCGGC
TCGCTGCGCC CGCTCGACAC GTTCCGCGTG CTGTCGCAGC CCTACCCGCG GCCCGAACTG
CTGTGCGCCT TCCGCCACCC GCCGCTCTAC CCCGGGCCCG CGCACGGACT GGGCGCCTCT
GCCGGCGGCC CCTGCTCCTG CCTCGCCTGT CACAGCGGCC CGGCCAACGG GCTGGCGCCC
CGGGCTGCCG CCGCCTCGGA CTTCACCTGT GCCTCCACCT CCCGCTCGGA CTCCTTCCTC
ACCTTCGCGC CCTCGGTGCT CAGCAAGGCC TCCTCCGTCG CGCTGGACCA GAGGGAGGAG
GTGCCCCTCA CTAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011513475.1
CDS159..836
Misc Feature(1)162..338(+)
Misc Feature(2)162..332(+)
Misc Feature(3)168..320(+)
Translation

Target ORF information:

RefSeq Version XM_011515173
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens even-skipped homeobox 1 (EVX1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011515173

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGCGTCGTT ACCGCACCGC CTTCACCCGA GAGCAGATTG CGCGGCTGGA GAAGGAATTC 
TACCGGGAGA ACTACGTATC CAGGCCGCGG AGATGTGAGC TGGCGGCCGC CCTAAACCTG
CCGGAAACCA CCATCAAGGT GTGGTTCCAG AACCGGCGCA TGAAGGACAA GCGGCAGCGC
CTGGCCATGA CGTGGCCGCA CCCGGCGGAC CCCGCCTTCT ACACTTACAT GATGAGCCAT
GCGGCGGCCG CGGGCGGCCT GCCCTACCCC TTCCCATCGC ACCTGCCCCT GCCCTACTAC
TCGCCGGTGG GCCTGGGCGC CGCATCCGCC GCCTCCGCCG CCGCCTCGCC CTTCAGCGGC
TCGCTGCGCC CGCTCGACAC GTTCCGCGTG CTGTCGCAGC CCTACCCGCG GCCCGAACTG
CTGTGCGCCT TCCGCCACCC GCCGCTCTAC CCCGGGCCCG CGCACGGACT GGGCGCCTCT
GCCGGCGGCC CCTGCTCCTG CCTCGCCTGT CACAGCGGCC CGGCCAACGG GCTGGCGCCC
CGGGCTGCCG CCGCCTCGGA CTTCACCTGT GCCTCCACCT CCCGCTCGGA CTCCTTCCTC
ACCTTCGCGC CCTCGGTGCT CAGCAAGGCC TCCTCCGTCG CGCTGGACCA GAGGGAGGAG
GTGCCCCTCA CTAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11389
Clone ID Related Accession (Same CDS sequence) NM_001989
Accession Version NM_001989.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1224bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product homeobox even-skipped homolog protein 1 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004080.2, X60655.1 and KF458418.1. On Jan 30, 2015 this sequence version replaced gi:84043964. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: X60655.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAGAGCC GAAAGGACAT GGTTGTGTTT CTGGATGGGG GTCAGCTTGG CACTCTGGTT 
GGCAAGAGAG TCTCAAATTT GTCCGAAGCC GTGGGCAGCC CGCTGCCGGA GCCGCCCGAG
AAAATGGTGC CCCGTGGTTG CCTGAGCCCT CGGGCCGTCC CTCCGGCCAC CCGGGAGCGC
GGCGGGGGAG GCCCGGAGGA GGAGCCGGTA GATGGACTCG CAGGCAGCGC GGCGGGGCCG
GGCGCCGAGC CCCAGGTAGC TGGGGCGGCC ATGCTCGGCC CAGGACCCCC GGCCCCCTCA
GTCGACAGCC TCTCCGGACA GGGGCAACCC AGTAGCTCGG ACACCGAGTC GGATTTCTAT
GAAGAAATCG AGGTGAGCTG CACCCCGGAC TGCGCCACCG GGAACGCCGA GTACCAGCAC
AGCAAAGGGT CCGGCTCCGA GGCGCTGGTC GGCAGTCCGA ACGGAGGGAG CGAGACCCCC
AAGAGCAACG GCGGCAGTGG TGGGGGCGGC TCGCAAGGCA CCCTGGCGTG CAGCGCCAGT
GACCAGATGC GTCGTTACCG CACCGCCTTC ACCCGAGAGC AGATTGCGCG GCTGGAGAAG
GAATTCTACC GGGAGAACTA CGTATCCAGG CCGCGGAGAT GTGAGCTGGC GGCCGCCCTA
AACCTGCCGG AAACCACCAT CAAGGTGTGG TTCCAGAACC GGCGCATGAA GGACAAGCGG
CAGCGCCTGG CCATGACGTG GCCGCACCCG GCGGACCCCG CCTTCTACAC TTACATGATG
AGCCATGCGG CGGCCGCGGG CGGCCTGCCC TACCCCTTCC CATCGCACCT GCCCCTGCCC
TACTACTCGC CGGTGGGCCT GGGCGCCGCA TCCGCCGCCT CCGCCGCCGC CTCGCCCTTC
AGCGGCTCGC TGCGCCCGCT CGACACGTTC CGCGTGCTGT CGCAGCCCTA CCCGCGGCCC
GAACTGCTGT GCGCCTTCCG CCACCCGCCG CTCTACCCCG GGCCCGCGCA CGGACTGGGC
GCCTCTGCCG GCGGCCCCTG CTCCTGCCTC GCCTGTCACA GCGGCCCGGC CAACGGGCTG
GCGCCCCGGG CTGCCGCCGC CTCGGACTTC ACCTGTGCCT CCACCTCCCG CTCGGACTCC
TTCCTCACCT TCGCGCCCTC GGTGCTCAGC AAGGCCTCCT CCGTCGCGCT GGACCAGAGG
GAGGAGGTGC CCCTCACTAG ATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001980.1
CDS487..1710
Misc Feature(1)199..201(+)
Misc Feature(2)1036..1212(+)
Misc Feature(3)1036..1206(+)
Misc Feature(4)1042..1194(+)
Exon (1)1..913
Gene:EVX1
Gene Synonym:
Exon (2)914..1170
Gene:EVX1
Gene Synonym:
Exon (3)1171..3104
Gene:EVX1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001989
Organism Homo sapiens (human)
Definition Homo sapiens even-skipped homeobox 1 (EVX1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001989

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAGAGCC GAAAGGACAT GGTTGTGTTT CTGGATGGGG GTCAGCTTGG CACTCTGGTT 
GGCAAGAGAG TCTCAAATTT GTCCGAAGCC GTGGGCAGCC CGCTGCCGGA GCCGCCCGAG
AAAATGGTGC CCCGTGGTTG CCTGAGCCCT CGGGCCGTCC CTCCGGCCAC CCGGGAGCGC
GGCGGGGGAG GCCCGGAGGA GGAGCCGGTA GATGGACTCG CAGGCAGCGC GGCGGGGCCG
GGCGCCGAGC CCCAGGTAGC TGGGGCGGCC ATGCTCGGCC CAGGACCCCC GGCCCCCTCA
GTCGACAGCC TCTCCGGACA GGGGCAACCC AGTAGCTCGG ACACCGAGTC GGATTTCTAT
GAAGAAATCG AGGTGAGCTG CACCCCGGAC TGCGCCACCG GGAACGCCGA GTACCAGCAC
AGCAAAGGGT CCGGCTCCGA GGCGCTGGTC GGCAGTCCGA ACGGAGGGAG CGAGACCCCC
AAGAGCAACG GCGGCAGTGG TGGGGGCGGC TCGCAAGGCA CCCTGGCGTG CAGCGCCAGT
GACCAGATGC GTCGTTACCG CACCGCCTTC ACCCGAGAGC AGATTGCGCG GCTGGAGAAG
GAATTCTACC GGGAGAACTA CGTATCCAGG CCGCGGAGAT GTGAGCTGGC GGCCGCCCTA
AACCTGCCGG AAACCACCAT CAAGGTGTGG TTCCAGAACC GGCGCATGAA GGACAAGCGG
CAGCGCCTGG CCATGACGTG GCCGCACCCG GCGGACCCCG CCTTCTACAC TTACATGATG
AGCCATGCGG CGGCCGCGGG CGGCCTGCCC TACCCCTTCC CATCGCACCT GCCCCTGCCC
TACTACTCGC CGGTGGGCCT GGGCGCCGCA TCCGCCGCCT CCGCCGCCGC CTCGCCCTTC
AGCGGCTCGC TGCGCCCGCT CGACACGTTC CGCGTGCTGT CGCAGCCCTA CCCGCGGCCC
GAACTGCTGT GCGCCTTCCG CCACCCGCCG CTCTACCCCG GGCCCGCGCA CGGACTGGGC
GCCTCTGCCG GCGGCCCCTG CTCCTGCCTC GCCTGTCACA GCGGCCCGGC CAACGGGCTG
GCGCCCCGGG CTGCCGCCGC CTCGGACTTC ACCTGTGCCT CCACCTCCCG CTCGGACTCC
TTCCTCACCT TCGCGCCCTC GGTGCTCAGC AAGGCCTCCT CCGTCGCGCT GGACCAGAGG
GAGGAGGTGC CCCTCACTAG ATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu41092
Clone ID Related Accession (Same CDS sequence) NM_001304519 , NM_001304520 , XM_011515173
Accession Version NM_001304519.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 678bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product homeobox even-skipped homolog protein 1 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK299188.1, AC004080.2, AK314155.1 and KF458418.1. On Jan 30, 2015 this sequence version replaced gi:530384530. Transcript Variant: This variant (2) uses an alternate splice site in the 5'-terminal exon and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. Both variants 2 and 3 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK314155.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2159368 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGCGTCGTT ACCGCACCGC CTTCACCCGA GAGCAGATTG CGCGGCTGGA GAAGGAATTC 
TACCGGGAGA ACTACGTATC CAGGCCGCGG AGATGTGAGC TGGCGGCCGC CCTAAACCTG
CCGGAAACCA CCATCAAGGT GTGGTTCCAG AACCGGCGCA TGAAGGACAA GCGGCAGCGC
CTGGCCATGA CGTGGCCGCA CCCGGCGGAC CCCGCCTTCT ACACTTACAT GATGAGCCAT
GCGGCGGCCG CGGGCGGCCT GCCCTACCCC TTCCCATCGC ACCTGCCCCT GCCCTACTAC
TCGCCGGTGG GCCTGGGCGC CGCATCCGCC GCCTCCGCCG CCGCCTCGCC CTTCAGCGGC
TCGCTGCGCC CGCTCGACAC GTTCCGCGTG CTGTCGCAGC CCTACCCGCG GCCCGAACTG
CTGTGCGCCT TCCGCCACCC GCCGCTCTAC CCCGGGCCCG CGCACGGACT GGGCGCCTCT
GCCGGCGGCC CCTGCTCCTG CCTCGCCTGT CACAGCGGCC CGGCCAACGG GCTGGCGCCC
CGGGCTGCCG CCGCCTCGGA CTTCACCTGT GCCTCCACCT CCCGCTCGGA CTCCTTCCTC
ACCTTCGCGC CCTCGGTGCT CAGCAAGGCC TCCTCCGTCG CGCTGGACCA GAGGGAGGAG
GTGCCCCTCA CTAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001291448.1
CDS978..1655
Misc Feature(1)846..848(+)
Misc Feature(2)981..1157(+)
Misc Feature(3)981..1151(+)
Misc Feature(4)987..1139(+)
Exon (1)1..858
Gene:EVX1
Gene Synonym:
Exon (2)859..1115
Gene:EVX1
Gene Synonym:
Exon (3)1116..3049
Gene:EVX1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001304519
Organism Homo sapiens (human)
Definition Homo sapiens even-skipped homeobox 1 (EVX1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001304519

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGCGTCGTT ACCGCACCGC CTTCACCCGA GAGCAGATTG CGCGGCTGGA GAAGGAATTC 
TACCGGGAGA ACTACGTATC CAGGCCGCGG AGATGTGAGC TGGCGGCCGC CCTAAACCTG
CCGGAAACCA CCATCAAGGT GTGGTTCCAG AACCGGCGCA TGAAGGACAA GCGGCAGCGC
CTGGCCATGA CGTGGCCGCA CCCGGCGGAC CCCGCCTTCT ACACTTACAT GATGAGCCAT
GCGGCGGCCG CGGGCGGCCT GCCCTACCCC TTCCCATCGC ACCTGCCCCT GCCCTACTAC
TCGCCGGTGG GCCTGGGCGC CGCATCCGCC GCCTCCGCCG CCGCCTCGCC CTTCAGCGGC
TCGCTGCGCC CGCTCGACAC GTTCCGCGTG CTGTCGCAGC CCTACCCGCG GCCCGAACTG
CTGTGCGCCT TCCGCCACCC GCCGCTCTAC CCCGGGCCCG CGCACGGACT GGGCGCCTCT
GCCGGCGGCC CCTGCTCCTG CCTCGCCTGT CACAGCGGCC CGGCCAACGG GCTGGCGCCC
CGGGCTGCCG CCGCCTCGGA CTTCACCTGT GCCTCCACCT CCCGCTCGGA CTCCTTCCTC
ACCTTCGCGC CCTCGGTGCT CAGCAAGGCC TCCTCCGTCG CGCTGGACCA GAGGGAGGAG
GTGCCCCTCA CTAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations
Am. J. Hum. Genet. 93 (3), 545-554 (2013)
Franceschini N, Fox E, Zhang Z, Edwards TL, Nalls MA, Sung YJ, Tayo BO, Sun YV, Gottesman O, Adeyemo A, Johnson AD, Young JH, Rice K, Duan Q, Chen F, Li Y, Tang H, Fornage M, Keene KL, Andrews JS, Smith JA, Faul JD, Guangfa Z, Guo W, Liu Y, Murray SS, Musani SK, Srinivasan S, Velez Edwards DR, Wang H, Becker LC, Bovet P, Bochud M, Broeckel U, Burnier M, Carty C, Chasman DI, Ehret G, Chen WM, Chen G, Chen W, Ding J, Dreisbach AW, Evans MK, Guo X, Garcia ME, Jensen R, Keller MF, Lettre G, Lotay V, Martin LW, Moore JH, Morrison AC, Mosley TH, Ogunniyi A, Palmas W, Papanicolaou G, Penman A, Polak JF, Ridker PM, Salako B, Singleton AB, Shriner D, Taylor KD, Vasan R, Wiggins K, Williams SM, Yanek LR, Zhao W, Zonderman AB, Becker DM, Berenson G, Boerwinkle E, Bottinger E, Cushman M, Eaton C, Nyberg F, Heiss G, Hirschhron JN, Howard VJ, Karczewsk KJ, Lanktree MB, Liu K, Liu Y, Loos R, Margolis K, Snyder M, Psaty BM, Schork NJ, Weir DR, Rotimi CN, Sale MM, Harris T, Kardia SL, Hunt SC, Arnett D, Redline S, Cooper RS, Risch NJ, Rao DC, Rotter JI, Chakravarti A, Reiner AP, Levy D, Keating BJ and Zhu X.


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EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differentiation by directly repressing GOOSECOID expression
Dev. Biol. 362 (1), 94-103 (2012)
Kalisz M, Winzi M, Bisgaard HC and Serup P.


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Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium
Circ Cardiovasc Genet 3 (3), 256-266 (2010)
Smith NL, Felix JF, Morrison AC, Demissie S, Glazer NL, Loehr LR, Cupples LA, Dehghan A, Lumley T, Rosamond WD, Lieb W, Rivadeneira F, Bis JC, Folsom AR, Benjamin E, Aulchenko YS, Haritunians T, Couper D, Murabito J, Wang YA, Stricker BH, Gottdiener JS, Chang PP, Wang TJ, Rice KM, Hofman A, Heckbert SR, Fox ER, O'Donnell CJ, Uitterlinden AG, Rotter JI, Willerson JT, Levy D, van Duijn CM, Psaty BM, Witteman JC, Boerwinkle E and Vasan RS.


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Transcriptional repression by the human homeobox protein EVX1 in transfected mammalian cells
J. Biol. Chem. 270 (46), 27695-27701 (1995)
Briata P, Van De Werken R, Airoldi I, Ilengo C, Di Blas E, Boncinelli E and Corte G.


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Isolation and mapping of EVX1, a human homeobox gene homologous to even-skipped, localized at the 5' end of HOX1 locus on chromosome 7
Nucleic Acids Res. 19 (23), 6541-6545 (1991)
Faiella A, D'Esposito M, Rambaldi M, Acampora D, Balsofiore S, Stornaiuolo A, Mallamaci A, Migliaccio E, Gulisano M and Simeone A.


 
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