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ALB cDNA ORF clone, Homo sapiens (human)

Gene Symbol ALB
Entrez Gene ID 213
Full Name albumin
Synonyms ANALBA, FDAH, PRO0883, PRO0903, PRO1341
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q13.3

Summary Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

103600

Disorder Html: Analbuminemia (3); [Dysalbuminemic hyperthyroxinemia] (3);

mRNA and Protein(s)

mRNA Protein Name
NM_000477 NP_000468 serum albumin preproprotein



Homo sapiens (human) ALB NP_000468.1
Pan troglodytes (chimpanzee) ALB XP_517233.3
Macaca mulatta (Rhesus monkey) ALB XP_001103956.1
Canis lupus familiaris (dog) ALB NP_001003026.1
Bos taurus (cattle) ALB NP_851335.1
Mus musculus (house mouse) Alb NP_033784.2
Rattus norvegicus (Norway rat) Alb NP_599153.2
Gallus gallus (chicken) ALB NP_990592.1
Xenopus (Silurana) tropicalis (western clawed frog) cars2 NP_001004887.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ALB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu18744
NM_000477 Homo sapiens albumin (ALB), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu18744
Clone ID Related Accession (Same CDS sequence) NM_000477
Accession Version NM_000477.5 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1830bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product serum albumin preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA642320.1, DQ986150.1 and N53869.1. This sequence is a reference standard in the RefSeqGene project. On Dec 5, 2008 this sequence version replaced gi:186659515. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: V00495.1, AF542069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGAAGTGGG TAACCTTTAT TTCCCTTCTT TTTCTCTTTA GCTCGGCTTA TTCCAGGGGT 
GTGTTTCGTC GAGATGCACA CAAGAGTGAG GTTGCTCATC GGTTTAAAGA TTTGGGAGAA
GAAAATTTCA AAGCCTTGGT GTTGATTGCC TTTGCTCAGT ATCTTCAGCA GTGTCCATTT
GAAGATCATG TAAAATTAGT GAATGAAGTA ACTGAATTTG CAAAAACATG TGTTGCTGAT
GAGTCAGCTG AAAATTGTGA CAAATCACTT CATACCCTTT TTGGAGACAA ATTATGCACA
GTTGCAACTC TTCGTGAAAC CTATGGTGAA ATGGCTGACT GCTGTGCAAA ACAAGAACCT
GAGAGAAATG AATGCTTCTT GCAACACAAA GATGACAACC CAAACCTCCC CCGATTGGTG
AGACCAGAGG TTGATGTGAT GTGCACTGCT TTTCATGACA ATGAAGAGAC ATTTTTGAAA
AAATACTTAT ATGAAATTGC CAGAAGACAT CCTTACTTTT ATGCCCCGGA ACTCCTTTTC
TTTGCTAAAA GGTATAAAGC TGCTTTTACA GAATGTTGCC AAGCTGCTGA TAAAGCTGCC
TGCCTGTTGC CAAAGCTCGA TGAACTTCGG GATGAAGGGA AGGCTTCGTC TGCCAAACAG
AGACTCAAGT GTGCCAGTCT CCAAAAATTT GGAGAAAGAG CTTTCAAAGC ATGGGCAGTA
GCTCGCCTGA GCCAGAGATT TCCCAAAGCT GAGTTTGCAG AAGTTTCCAA GTTAGTGACA
GATCTTACCA AAGTCCACAC GGAATGCTGC CATGGAGATC TGCTTGAATG TGCTGATGAC
AGGGCGGACC TTGCCAAGTA TATCTGTGAA AATCAAGATT CGATCTCCAG TAAACTGAAG
GAATGCTGTG AAAAACCTCT GTTGGAAAAA TCCCACTGCA TTGCCGAAGT GGAAAATGAT
GAGATGCCTG CTGACTTGCC TTCATTAGCT GCTGATTTTG TTGAAAGTAA GGATGTTTGC
AAAAACTATG CTGAGGCAAA GGATGTCTTC CTGGGCATGT TTTTGTATGA ATATGCAAGA
AGGCATCCTG ATTACTCTGT CGTGCTGCTG CTGAGACTTG CCAAGACATA TGAAACCACT
CTAGAGAAGT GCTGTGCCGC TGCAGATCCT CATGAATGCT ATGCCAAAGT GTTCGATGAA
TTTAAACCTC TTGTGGAAGA GCCTCAGAAT TTAATCAAAC AAAATTGTGA GCTTTTTGAG
CAGCTTGGAG AGTACAAATT CCAGAATGCG CTATTAGTTC GTTACACCAA GAAAGTACCC
CAAGTGTCAA CTCCAACTCT TGTAGAGGTC TCAAGAAACC TAGGAAAAGT GGGCAGCAAA
TGTTGTAAAC ATCCTGAAGC AAAAAGAATG CCCTGTGCAG AAGACTATCT ATCCGTGGTC
CTGAACCAGT TATGTGTGTT GCATGAGAAA ACGCCAGTAA GTGACAGAGT CACCAAATGC
TGCACAGAAT CCTTGGTGAA CAGGCGACCA TGCTTTTCAG CTCTGGAAGT CGATGAAACA
TACGTTCCCA AAGAGTTTAA TGCTGAAACA TTCACCTTCC ATGCAGATAT ATGCACACTT
TCTGAGAAGG AGAGACAAAT CAAGAAACAA ACTGCACTTG TTGAGCTCGT GAAACACAAG
CCCAAGGCAA CAAAAGAGCA ACTGAAAGCT GTTATGGATG ATTTCGCAGC TTTTGTAGAG
AAGTGCTGCA AGGCTGACGA TAAGGAGACC TGCTTTGCCG AGGAGGGTAA AAAACTTGTT
GCTGCAAGTC AAGCTGCCTT AGGCTTATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000468.1
CDS74..1903
Misc Feature(1)14..16(+)
Misc Feature(2)155..157(+)
Misc Feature(3)158..700(+)
Misc Feature(4)179..181(+)
Misc Feature(5)203..205(+)
Misc Feature(6)224..454(+)
Misc Feature(7)266..268(+)
Misc Feature(8)302..331(+)
Misc Feature(9)317..319(+)
Misc Feature(10)335..337(+)
Misc Feature(11)362..364(+)
Misc Feature(12)368..418(+)
Misc Feature(13)413..448(+)
Misc Feature(14)422..424(+)
Misc Feature(15)461..463(+)
Misc Feature(16)515..652(+)
Misc Feature(17)548..628(+)
Misc Feature(18)551..553(+)
Misc Feature(19)563..565(+)
Misc Feature(20)620..622(+)
Misc Feature(21)647..676(+)
Misc Feature(22)665..667(+)
Misc Feature(23)686..688(+)
Misc Feature(24)713..715(+)
Misc Feature(25)728..730(+)
Misc Feature(26)734..1276(+)
Misc Feature(27)740..742(+)
Misc Feature(28)740..742(+)
Misc Feature(29)740..742(+)
Misc Feature(30)743..883(+)
Misc Feature(31)758..760(+)
Misc Feature(32)779..781(+)
Misc Feature(33)800..1018(+)
Misc Feature(34)842..844(+)
Misc Feature(35)863..865(+)
Misc Feature(36)878..904(+)
Misc Feature(37)929..931(+)
Misc Feature(38)938..982(+)
Misc Feature(39)965..967(+)
Misc Feature(40)977..1012(+)
Misc Feature(41)986..988(+)
Misc Feature(42)1001..1003(+)
Misc Feature(43)1067..1069(+)
Misc Feature(44)1091..1228(+)
Misc Feature(45)1094..1096(+)
Misc Feature(46)1124..1204(+)
Misc Feature(47)1196..1198(+)
Misc Feature(48)1220..1222(+)
Misc Feature(49)1223..1252(+)
Misc Feature(50)1259..1261(+)
Misc Feature(51)1310..1870(+)
Misc Feature(52)1310..1312(+)
Misc Feature(53)1319..1459(+)
Misc Feature(54)1349..1351(+)
Misc Feature(55)1376..1612(+)
Misc Feature(56)1385..1387(+)
Misc Feature(57)1400..1402(+)
Misc Feature(58)1403..1405(+)
Misc Feature(59)1409..1411(+)
Misc Feature(60)1412..1414(+)
Misc Feature(61)1439..1441(+)
Misc Feature(62)1451..1453(+)
Misc Feature(63)1454..1489(+)
Misc Feature(64)1460..1462(+)
Misc Feature(65)1526..1576(+)
Misc Feature(66)1541..1543(+)
Misc Feature(67)1568..1570(+)
Misc Feature(68)1571..1606(+)
Misc Feature(69)1634..1636(+)
Misc Feature(70)1643..1645(+)
Misc Feature(71)1685..1822(+)
Misc Feature(72)1700..1702(+)
Misc Feature(73)1715..1717(+)
Misc Feature(74)1718..1798(+)
Misc Feature(75)1718..1720(+)
Misc Feature(76)1745..1747(+)
Misc Feature(77)1757..1759(+)
Misc Feature(78)1766..1768(+)
Misc Feature(79)1814..1816(+)
Misc Feature(80)1817..1846(+)
Misc Feature(81)1823..1825(+)
Misc Feature(82)1835..1837(+)
Misc Feature(83)1865..1867(+)
Exon (1)1..152
Gene:ALB
Gene Synonym:
Exon (2)153..210
Gene:ALB
Gene Synonym:
Exon (3)211..343
Gene:ALB
Gene Synonym:
Exon (4)344..555
Gene:ALB
Gene Synonym:
Exon (5)556..688
Gene:ALB
Gene Synonym:
Exon (6)689..786
Gene:ALB
Gene Synonym:
Exon (7)787..916
Gene:ALB
Gene Synonym:
Exon (8)917..1131
Gene:ALB
Gene Synonym:
Exon (9)1132..1264
Gene:ALB
Gene Synonym:
Exon (10)1265..1362
Gene:ALB
Gene Synonym:
Exon (11)1363..1501
Gene:ALB
Gene Synonym:
Exon (12)1502..1725
Gene:ALB
Gene Synonym:
Exon (13)1726..1858
Gene:ALB
Gene Synonym:
Exon (14)1859..1926
Gene:ALB
Gene Synonym:
Exon (15)1927..2247
Gene:ALB
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000477
Organism Homo sapiens (human)
Definition Homo sapiens albumin (ALB), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000477

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGAAGTGGG TAACCTTTAT TTCCCTTCTT TTTCTCTTTA GCTCGGCTTA TTCCAGGGGT 
GTGTTTCGTC GAGATGCACA CAAGAGTGAG GTTGCTCATC GGTTTAAAGA TTTGGGAGAA
GAAAATTTCA AAGCCTTGGT GTTGATTGCC TTTGCTCAGT ATCTTCAGCA GTGTCCATTT
GAAGATCATG TAAAATTAGT GAATGAAGTA ACTGAATTTG CAAAAACATG TGTTGCTGAT
GAGTCAGCTG AAAATTGTGA CAAATCACTT CATACCCTTT TTGGAGACAA ATTATGCACA
GTTGCAACTC TTCGTGAAAC CTATGGTGAA ATGGCTGACT GCTGTGCAAA ACAAGAACCT
GAGAGAAATG AATGCTTCTT GCAACACAAA GATGACAACC CAAACCTCCC CCGATTGGTG
AGACCAGAGG TTGATGTGAT GTGCACTGCT TTTCATGACA ATGAAGAGAC ATTTTTGAAA
AAATACTTAT ATGAAATTGC CAGAAGACAT CCTTACTTTT ATGCCCCGGA ACTCCTTTTC
TTTGCTAAAA GGTATAAAGC TGCTTTTACA GAATGTTGCC AAGCTGCTGA TAAAGCTGCC
TGCCTGTTGC CAAAGCTCGA TGAACTTCGG GATGAAGGGA AGGCTTCGTC TGCCAAACAG
AGACTCAAGT GTGCCAGTCT CCAAAAATTT GGAGAAAGAG CTTTCAAAGC ATGGGCAGTA
GCTCGCCTGA GCCAGAGATT TCCCAAAGCT GAGTTTGCAG AAGTTTCCAA GTTAGTGACA
GATCTTACCA AAGTCCACAC GGAATGCTGC CATGGAGATC TGCTTGAATG TGCTGATGAC
AGGGCGGACC TTGCCAAGTA TATCTGTGAA AATCAAGATT CGATCTCCAG TAAACTGAAG
GAATGCTGTG AAAAACCTCT GTTGGAAAAA TCCCACTGCA TTGCCGAAGT GGAAAATGAT
GAGATGCCTG CTGACTTGCC TTCATTAGCT GCTGATTTTG TTGAAAGTAA GGATGTTTGC
AAAAACTATG CTGAGGCAAA GGATGTCTTC CTGGGCATGT TTTTGTATGA ATATGCAAGA
AGGCATCCTG ATTACTCTGT CGTGCTGCTG CTGAGACTTG CCAAGACATA TGAAACCACT
CTAGAGAAGT GCTGTGCCGC TGCAGATCCT CATGAATGCT ATGCCAAAGT GTTCGATGAA
TTTAAACCTC TTGTGGAAGA GCCTCAGAAT TTAATCAAAC AAAATTGTGA GCTTTTTGAG
CAGCTTGGAG AGTACAAATT CCAGAATGCG CTATTAGTTC GTTACACCAA GAAAGTACCC
CAAGTGTCAA CTCCAACTCT TGTAGAGGTC TCAAGAAACC TAGGAAAAGT GGGCAGCAAA
TGTTGTAAAC ATCCTGAAGC AAAAAGAATG CCCTGTGCAG AAGACTATCT ATCCGTGGTC
CTGAACCAGT TATGTGTGTT GCATGAGAAA ACGCCAGTAA GTGACAGAGT CACCAAATGC
TGCACAGAAT CCTTGGTGAA CAGGCGACCA TGCTTTTCAG CTCTGGAAGT CGATGAAACA
TACGTTCCCA AAGAGTTTAA TGCTGAAACA TTCACCTTCC ATGCAGATAT ATGCACACTT
TCTGAGAAGG AGAGACAAAT CAAGAAACAA ACTGCACTTG TTGAGCTCGT GAAACACAAG
CCCAAGGCAA CAAAAGAGCA ACTGAAAGCT GTTATGGATG ATTTCGCAGC TTTTGTAGAG
AAGTGCTGCA AGGCTGACGA TAAGGAGACC TGCTTTGCCG AGGAGGGTAA AAAACTTGTT
GCTGCAAGTC AAGCTGCCTT AGGCTTATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Transcriptional regulation of the albumin gene depends on the removal of histone methylation marks by the FAD-dependent monoamine oxidase lysine-specific demethylase 1 in HepG2 human hepatocarcinoma cells
J. Nutr. 144 (7), 997-1001 (2014)
Liu D and Zempleni J.


book

Mutations and polymorphisms of the gene of the major human blood protein, serum albumin
Hum. Mutat. 29 (8), 1007-1016 (2008)
Minchiotti L, Galliano M, Kragh-Hansen U and Peters T Jr.


book

Crystal structure of human serum albumin at 2.5 A resolution
Protein Eng. 12 (6), 439-446 (1999)
Sugio S, Kashima A, Mochizuki S, Noda M and Kobayashi K.


book

Atomic structure and chemistry of human serum albumin
Nature 358 (6383), 209-215 (1992)
He XM and Carter DC.


book

Structure of human serum albumin
Science 249 (4966), 302-303 (1990)
Carter DC and He XM.


book

The human albumin gene. Characterization of the 5' and 3' flanking regions and the polymorphic gene transcripts
J. Biol. Chem. 261 (7), 3244-3251 (1986)
Urano,Y., Watanabe,K., Sakai,M. and Tamaoki,T.


book

The human serum albumin gene: structure of a unique locus
Gene 19 (1), 55-58 (1982)
Hawkins,J.W. and Dugaiczyk,A.


book

Nucleotide sequence and the encoded amino acids of human serum albumin mRNA
Proc. Natl. Acad. Sci. U.S.A. 79 (1), 71-75 (1982)
Dugaiczyk,A., Law,S.W. and Dennison,O.E.


book

Limited pepsin digestion of human plasma albumin
J. Biol. Chem. 252 (12), 4326-4329 (1977)
Heaney-Kieras,J. and King,T.P.


book

Complete amino acid sequence of human serum albumin
FEBS Lett. 58 (1), 134-137 (1975)
Meloun,B., Moravek,L. and Kostka,V.


 
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