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F5 cDNA ORF clone, Homo sapiens (human)

Gene Symbol F5
Entrez Gene ID 2153
Full Name coagulation factor V (proaccelerin, labile factor)
Synonyms FVL, PCCF, RPRGL1, THPH2
General protein information
Preferred Names
coagulation factor V
Names
coagulation factor V
factor V Leiden
proaccelerin, labile factor
activated protein c cofactor
coagulation factor V jinjiang A2 domain
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q23

Summary This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq, Oct 2008]. lac of sum
Disorder MIM:

612309

Disorder Html: Factor V deficiency, 227400 (3); {Thrombophilia, susceptibility to,

mRNA and Protein(s)

mRNA Protein Name
NM_000130 NP_000121 coagulation factor V precursor



Homo sapiens (human) F5 NP_000121.2
Pan troglodytes (chimpanzee) F5 XP_513984.4
Macaca mulatta (Rhesus monkey) F5 XP_001093072.2
Canis lupus familiaris (dog) F5 XP_005622605.1
Bos taurus (cattle) F5 NP_776304.1
Mus musculus (house mouse) F5 NP_032002.1
Rattus norvegicus (Norway rat) F5 NP_001041343.1
Gallus gallus (chicken) F5 XP_001231901.3
Danio rerio (zebrafish) f5 NP_001007209.2
Xenopus (Silurana) tropicalis (western clawed frog) f5 XP_002935820.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following F5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the F5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu26030 NM_000130 Homo sapiens coagulation factor V (proaccelerin, labile factor) (F5), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $923.30
$1319.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu26030
Clone ID Related Accession (Same CDS sequence) NM_000130
Accession Version NM_000130.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 6675bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product coagulation factor V precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU279657.1, AK226079.1, M16967.1 and Z99572.1. This sequence is a reference standard in the RefSeqGene project. On Dec 14, 2006 this sequence version replaced gi:105990534. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M16967.1, AK226079.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
ATGTTCCCAG GCTGCCCACG CCTCTGGGTC CTGGTGGTCT TGGGCACCAG CTGGGTAGGC 
TGGGGGAGCC AAGGGACAGA AGCGGCACAG CTAAGGCAGT TCTACGTGGC TGCTCAGGGC
ATCAGTTGGA GCTACCGACC TGAGCCCACA AACTCAAGTT TGAATCTTTC TGTAACTTCC
TTTAAGAAAA TTGTCTACAG AGAGTATGAA CCATATTTTA AGAAAGAAAA ACCACAATCT
ACCATTTCAG GACTTCTTGG GCCTACTTTA TATGCTGAAG TCGGAGACAT CATAAAAGTT
CACTTTAAAA ATAAGGCAGA TAAGCCCTTG AGCATCCATC CTCAAGGAAT TAGGTACAGT
AAATTATCAG AAGGTGCTTC TTACCTTGAC CACACATTCC CTGCGGAGAA GATGGACGAC
GCTGTGGCTC CAGGCCGAGA ATACACCTAT GAATGGAGTA TCAGTGAGGA CAGTGGACCC
ACCCATGATG ACCCTCCATG CCTCACACAC ATCTATTACT CCCATGAAAA TCTGATCGAG
GATTTCAACT CGGGGCTGAT TGGGCCCCTG CTTATCTGTA AAAAAGGGAC CCTAACTGAG
GGTGGGACAC AGAAGACGTT TGACAAGCAA ATCGTGCTAC TATTTGCTGT GTTTGATGAA
AGCAAGAGCT GGAGCCAGTC ATCATCCCTA ATGTACACAG TCAATGGATA TGTGAATGGG
ACAATGCCAG ATATAACAGT TTGTGCCCAT GACCACATCA GCTGGCATCT GCTGGGAATG
AGCTCGGGGC CAGAATTATT CTCCATTCAT TTCAACGGCC AGGTCCTGGA GCAGAACCAT
CATAAGGTCT CAGCCATCAC CCTTGTCAGT GCTACATCCA CTACCGCAAA TATGACTGTG
GGCCCAGAGG GAAAGTGGAT CATATCTTCT CTCACCCCAA AACATTTGCA AGCTGGGATG
CAGGCTTACA TTGACATTAA AAACTGCCCA AAGAAAACCA GGAATCTTAA GAAAATAACT
CGTGAGCAGA GGCGGCACAT GAAGAGGTGG GAATACTTCA TTGCTGCAGA GGAAGTCATT
TGGGACTATG CACCTGTAAT ACCAGCGAAT ATGGACAAAA AATACAGGTC TCAGCATTTG
GATAATTTCT CAAACCAAAT TGGAAAACAT TATAAGAAAG TTATGTACAC ACAGTACGAA
GATGAGTCCT TCACCAAACA TACAGTGAAT CCCAATATGA AAGAAGATGG GATTTTGGGT
CCTATTATCA GAGCCCAGGT CAGAGACACA CTCAAAATCG TGTTCAAAAA TATGGCCAGC
CGCCCCTATA GCATTTACCC TCATGGAGTG ACCTTCTCGC CTTATGAAGA TGAAGTCAAC
TCTTCTTTCA CCTCAGGCAG GAACAACACC ATGATCAGAG CAGTTCAACC AGGGGAAACC
TATACTTATA AGTGGAACAT CTTAGAGTTT GATGAACCCA CAGAAAATGA TGCCCAGTGC
TTAACAAGAC CATACTACAG TGACGTGGAC ATCATGAGAG ACATCGCCTC TGGGCTAATA
GGACTACTTC TAATCTGTAA GAGCAGATCC CTGGACAGGC GAGGAATACA GAGGGCAGCA
GACATCGAAC AGCAGGCTGT GTTTGCTGTG TTTGATGAGA ACAAAAGCTG GTACCTTGAG
GACAACATCA ACAAGTTTTG TGAAAATCCT GATGAGGTGA AACGTGATGA CCCCAAGTTT
TATGAATCAA ACATCATGAG CACTATCAAT GGCTATGTGC CTGAGAGCAT AACTACTCTT
GGATTCTGCT TTGATGACAC TGTCCAGTGG CACTTCTGTA GTGTGGGGAC CCAGAATGAA
ATTTTGACCA TCCACTTCAC TGGGCACTCA TTCATCTATG GAAAGAGGCA TGAGGACACC
TTGACCCTCT TCCCCATGCG TGGAGAATCT GTGACGGTCA CAATGGATAA TGTTGGAACT
TGGATGTTAA CTTCCATGAA TTCTAGTCCA AGAAGCAAAA AGCTGAGGCT GAAATTCAGG
GATGTTAAAT GTATCCCAGA TGATGATGAA GACTCATATG AGATTTTTGA ACCTCCAGAA
TCTACAGTCA TGGCTACACG GAAAATGCAT GATCGTTTAG AACCTGAAGA TGAAGAGAGT
GATGCTGACT ATGATTACCA GAACAGACTG GCTGCAGCAT TAGGAATCAG GTCATTCCGA
AACTCATCAT TGAATCAGGA AGAAGAAGAG TTCAATCTTA CTGCCCTAGC TCTGGAGAAT
GGCACTGAAT TCGTTTCTTC AAACACAGAT ATAATTGTTG GTTCAAATTA TTCTTCCCCA
AGTAATATTA GTAAGTTCAC TGTCAATAAC CTTGCAGAAC CTCAGAAAGC CCCTTCTCAC
CAACAAGCCA CCACAGCTGG TTCCCCACTG AGACACCTCA TTGGCAAGAA CTCAGTTCTC
AATTCTTCCA CAGCAGAGCA TTCCAGCCCA TATTCTGAAG ACCCTATAGA GGATCCTCTA
CAGCCAGATG TCACAGGGAT ACGTCTACTT TCACTTGGTG CTGGAGAATT CAAAAGTCAA
GAACATGCTA AGCATAAGGG ACCCAAGGTA GAAAGAGATC AAGCAGCAAA GCACAGGTTC
TCCTGGATGA AATTACTAGC ACATAAAGTT GGGAGACACC TAAGCCAAGA CACTGGTTCT
CCTTCCGGAA TGAGGCCCTG GGAGGACCTT CCTAGCCAAG ACACTGGTTC TCCTTCCAGA
ATGAGGCCCT GGAAGGACCC TCCTAGTGAT CTGTTACTCT TAAAACAAAG TAACTCATCT
AAGATTTTGG TTGGGAGATG GCATTTGGCT TCTGAGAAAG GTAGCTATGA AATAATCCAA
GATACTGATG AAGACACAGC TGTTAACAAT TGGCTGATCA GCCCCCAGAA TGCCTCACGT
GCTTGGGGAG AAAGCACCCC TCTTGCCAAC AAGCCTGGAA AGCAGAGTGG CCACCCAAAG
TTTCCTAGAG TTAGACATAA ATCTCTACAA GTAAGACAGG ATGGAGGAAA GAGTAGACTG
AAGAAAAGCC AGTTTCTCAT TAAGACACGA AAAAAGAAAA AAGAGAAGCA CACACACCAT
GCTCCTTTAT CTCCGAGGAC CTTTCACCCT CTAAGAAGTG AAGCCTACAA CACATTTTCA
GAAAGAAGAC TTAAGCATTC GTTGGTGCTT CATAAATCCA ATGAAACATC TCTTCCCACA
GACCTCAATC AGACATTGCC CTCTATGGAT TTTGGCTGGA TAGCCTCACT TCCTGACCAT
AATCAGAATT CCTCAAATGA CACTGGTCAG GCAAGCTGTC CTCCAGGTCT TTATCAGACA
GTGCCCCCAG AGGAACACTA TCAAACATTC CCCATTCAAG ACCCTGATCA AATGCACTCT
ACTTCAGACC CCAGTCACAG ATCCTCTTCT CCAGAGCTCA GTGAAATGCT TGAGTATGAC
CGAAGTCACA AGTCCTTCCC CACAGATATA AGTCAAATGT CCCCTTCCTC AGAACATGAA
GTCTGGCAGA CAGTCATCTC TCCAGACCTC AGCCAGGTGA CCCTCTCTCC AGAACTCAGC
CAGACAAACC TCTCTCCAGA CCTCAGCCAC ACGACTCTCT CTCCAGAACT CATTCAGAGA
AACCTTTCCC CAGCCCTCGG TCAGATGCCC ATTTCTCCAG ACCTCAGCCA TACAACCCTT
TCTCCAGACC TCAGCCATAC AACCCTTTCT TTAGACCTCA GCCAGACAAA CCTCTCTCCA
GAACTCAGTC AGACAAACCT TTCTCCAGCC CTCGGTCAGA TGCCCCTTTC TCCAGACCTC
AGCCATACAA CCCTTTCTCT AGACTTCAGC CAGACAAACC TCTCTCCAGA ACTCAGCCAT
ATGACTCTCT CTCCAGAACT CAGTCAGACA AACCTTTCCC CAGCCCTCGG TCAGATGCCC
ATTTCTCCAG ACCTCAGCCA TACAACCCTT TCTCTAGACT TCAGCCAGAC AAACCTCTCT
CCAGAACTCA GTCAAACAAA CCTTTCCCCA GCCCTCGGTC AGATGCCCCT TTCTCCAGAC
CCCAGCCATA CAACCCTTTC TCTAGACCTC AGCCAGACAA ACCTCTCTCC AGAACTCAGT
CAGACAAACC TTTCCCCAGA CCTCAGTGAG ATGCCCCTCT TTGCAGATCT CAGTCAAATT
CCCCTTACCC CAGACCTCGA CCAGATGACA CTTTCTCCAG ACCTTGGTGA GACAGATCTT
TCCCCAAACT TTGGTCAGAT GTCCCTTTCC CCAGACCTCA GCCAGGTGAC TCTCTCTCCA
GACATCAGTG ACACCACCCT TCTCCCGGAT CTCAGCCAGA TATCACCTCC TCCAGACCTT
GATCAGATAT TCTACCCTTC TGAATCTAGT CAGTCATTGC TTCTTCAAGA ATTTAATGAG
TCTTTTCCTT ATCCAGACCT TGGTCAGATG CCATCTCCTT CATCTCCTAC TCTCAATGAT
ACTTTTCTAT CAAAGGAATT TAATCCACTG GTTATAGTGG GCCTCAGTAA AGATGGTACA
GATTACATTG AGATCATTCC AAAGGAAGAG GTCCAGAGCA GTGAAGATGA CTATGCTGAA
ATTGATTATG TGCCCTATGA TGACCCCTAC AAAACTGATG TTAGGACAAA CATCAACTCC
TCCAGAGATC CTGACAACAT TGCAGCATGG TACCTCCGCA GCAACAATGG AAACAGAAGA
AATTATTACA TTGCTGCTGA AGAAATATCC TGGGATTATT CAGAATTTGT ACAAAGGGAA
ACAGATATTG AAGACTCTGA TGATATTCCA GAAGATACCA CATATAAGAA AGTAGTTTTT
CGAAAGTACC TCGACAGCAC TTTTACCAAA CGTGATCCTC GAGGGGAGTA TGAAGAGCAT
CTCGGAATTC TTGGTCCTAT TATCAGAGCT GAAGTGGATG ATGTTATCCA AGTTCGTTTT
AAAAATTTAG CATCCAGACC GTATTCTCTA CATGCCCATG GACTTTCCTA TGAAAAATCA
TCAGAGGGAA AGACTTATGA AGATGACTCT CCTGAATGGT TTAAGGAAGA TAATGCTGTT
CAGCCAAATA GCAGTTATAC CTACGTATGG CATGCCACTG AGCGATCAGG GCCAGAAAGT
CCTGGCTCTG CCTGTCGGGC TTGGGCCTAC TACTCAGCTG TGAACCCAGA AAAAGATATT
CACTCAGGCT TGATAGGTCC CCTCCTAATC TGCCAAAAAG GAATACTACA TAAGGACAGC
AACATGCCTA TGGACATGAG AGAATTTGTC TTACTATTTA TGACCTTTGA TGAAAAGAAG
AGCTGGTACT ATGAAAAGAA GTCCCGAAGT TCTTGGAGAC TCACATCCTC AGAAATGAAA
AAATCCCATG AGTTTCACGC CATTAATGGG ATGATCTACA GCTTGCCTGG CCTGAAAATG
TATGAGCAAG AGTGGGTGAG GTTACACCTG CTGAACATAG GCGGCTCCCA AGACATTCAC
GTGGTTCACT TTCACGGCCA GACCTTGCTG GAAAATGGCA ATAAACAGCA CCAGTTAGGG
GTCTGGCCCC TTCTGCCTGG TTCATTTAAA ACTCTTGAAA TGAAGGCATC AAAACCTGGC
TGGTGGCTCC TAAACACAGA GGTTGGAGAA AACCAGAGAG CAGGGATGCA AACGCCATTT
CTTATCATGG ACAGAGACTG TAGGATGCCA ATGGGACTAA GCACTGGTAT CATATCTGAT
TCACAGATCA AGGCTTCAGA GTTTCTGGGT TACTGGGAGC CCAGATTAGC AAGATTAAAC
AATGGTGGAT CTTATAATGC TTGGAGTGTA GAAAAACTTG CAGCAGAATT TGCCTCTAAA
CCTTGGATCC AGGTGGACAT GCAAAAGGAA GTCATAATCA CAGGGATCCA GACCCAAGGT
GCCAAACACT ACCTGAAGTC CTGCTATACC ACAGAGTTCT ATGTAGCTTA CAGTTCCAAC
CAGATCAACT GGCAGATCTT CAAAGGGAAC AGCACAAGGA ATGTGATGTA TTTTAATGGC
AATTCAGATG CCTCTACAAT AAAAGAGAAT CAGTTTGACC CACCTATTGT GGCTAGATAT
ATTAGGATCT CTCCAACTCG AGCCTATAAC AGACCTACCC TTCGATTGGA ACTGCAAGGT
TGTGAGGTAA ATGGATGTTC CACACCCCTG GGTATGGAAA ATGGAAAGAT AGAAAACAAG
CAAATCACAG CTTCTTCGTT TAAGAAATCT TGGTGGGGAG ATTACTGGGA ACCCTTCCGT
GCCCGTCTGA ATGCCCAGGG ACGTGTGAAT GCCTGGCAAG CCAAGGCAAA CAACAATAAG
CAGTGGCTAG AAATTGATCT ACTCAAGATC AAGAAGATAA CGGCAATTAT AACACAGGGC
TGCAAGTCTC TGTCCTCTGA AATGTATGTA AAGAGCTATA CCATCCACTA CAGTGAGCAG
GGAGTGGAAT GGAAACCATA CAGGCTGAAA TCCTCCATGG TGGACAAGAT TTTTGAAGGA
AATACTAATA CCAAAGGACA TGTGAAGAAC TTTTTCAACC CCCCAATCAT TTCCAGGTTT
ATCCGTGTCA TTCCTAAAAC ATGGAATCAA AGTATTGCAC TTCGCCTGGA ACTCTTTGGC
TGTGATATTT ACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000121.2
CDS146..6820
Misc Feature(1)80..82(+)
Misc Feature(2)230..2356(+)
Misc Feature(3)239..733(+)
Misc Feature(4)767..1123(+)
Misc Feature(5)1145..1150(+)
Misc Feature(6)1145..1147(+)
Misc Feature(7)1187..1729(+)
Misc Feature(8)1250..1252(+)
Misc Feature(9)1745..1750(+)
Misc Feature(10)1745..1747(+)
Misc Feature(11)1751..1753(+)
Misc Feature(12)1766..2197(+)
Misc Feature(13)2063..2065(+)
Misc Feature(14)2219..2221(+)
Misc Feature(15)2222..2224(+)
Misc Feature(16)2264..2269(+)
Misc Feature(17)2264..2266(+)
Misc Feature(18)2315..2317(+)
Misc Feature(19)2321..2323(+)
Misc Feature(20)2354..2359(+)
Misc Feature(21)2354..2356(+)
Misc Feature(22)2357..4864(+)
Misc Feature(23)2684..2686(+)
Misc Feature(24)3209..3214(+)
Misc Feature(25)3209..3211(+)
Misc Feature(26)3281..3286(+)
Misc Feature(27)3281..3283(+)
Misc Feature(28)3803..3805(+)
Misc Feature(29)3872..>4507(+)
Misc Feature(30)4679..4681(+)
Misc Feature(31)4709..4711(+)
Misc Feature(32)4757..4759(+)
Misc Feature(33)4772..4774(+)
Misc Feature(34)4862..4867(+)
Misc Feature(35)4865..6817(+)
Misc Feature(36)4880..5407(+)
Misc Feature(37)4907..5392(+)
Misc Feature(38)4922..4924(+)
Misc Feature(39)5252..5254(+)
Misc Feature(40)5441..5851(+)
Misc Feature(41)5528..5530(+)
Misc Feature(42)5870..6325(+)
Misc Feature(43)5990..6109(+)
Misc Feature(44)6173..6175(+)
Misc Feature(45)6347..6805(+)
Misc Feature(46)6482..6589(+)
Misc Feature(47)6686..6688(+)
Misc Feature(48)6770..6772(+)
Exon (1)1..303
Gene:F5
Gene Synonym:
Exon (2)304..395
Gene:F5
Gene Synonym:
Exon (3)396..518
Gene:F5
Gene Synonym:
Exon (4)519..731
Gene:F5
Gene Synonym:
Exon (5)732..875
Gene:F5
Gene Synonym:
Exon (6)876..1097
Gene:F5
Gene Synonym:
Exon (7)1098..1263
Gene:F5
Gene Synonym:
Exon (8)1264..1441
Gene:F5
Gene Synonym:
Exon (9)1442..1541
Gene:F5
Gene Synonym:
Exon (10)1542..1756
Gene:F5
Gene Synonym:
Exon (11)1757..1907
Gene:F5
Gene Synonym:
Exon (12)1908..2120
Gene:F5
Gene Synonym:
Exon (13)2121..4941
Gene:F5
Gene Synonym:
Exon (14)4942..5116
Gene:F5
Gene Synonym:
Exon (15)5117..5353
Gene:F5
Gene Synonym:
Exon (16)5354..5564
Gene:F5
Gene Synonym:
Exon (17)5565..5744
Gene:F5
Gene Synonym:
Exon (18)5745..5861
Gene:F5
Gene Synonym:
Exon (19)5862..5933
Gene:F5
Gene Synonym:
Exon (20)5934..6037
Gene:F5
Gene Synonym:
Exon (21)6038..6193
Gene:F5
Gene Synonym:
Exon (22)6194..6338
Gene:F5
Gene Synonym:
Exon (23)6339..6490
Gene:F5
Gene Synonym:
Exon (24)6491..6673
Gene:F5
Gene Synonym:
Exon (25)6674..9179
Gene:F5
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000130
Organism Homo sapiens (human)
Definition Homo sapiens coagulation factor V (proaccelerin, labile factor) (F5), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000130

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
ATGTTCCCAG GCTGCCCACG CCTCTGGGTC CTGGTGGTCT TGGGCACCAG CTGGGTAGGC 
TGGGGGAGCC AAGGGACAGA AGCGGCACAG CTAAGGCAGT TCTACGTGGC TGCTCAGGGC
ATCAGTTGGA GCTACCGACC TGAGCCCACA AACTCAAGTT TGAATCTTTC TGTAACTTCC
TTTAAGAAAA TTGTCTACAG AGAGTATGAA CCATATTTTA AGAAAGAAAA ACCACAATCT
ACCATTTCAG GACTTCTTGG GCCTACTTTA TATGCTGAAG TCGGAGACAT CATAAAAGTT
CACTTTAAAA ATAAGGCAGA TAAGCCCTTG AGCATCCATC CTCAAGGAAT TAGGTACAGT
AAATTATCAG AAGGTGCTTC TTACCTTGAC CACACATTCC CTGCGGAGAA GATGGACGAC
GCTGTGGCTC CAGGCCGAGA ATACACCTAT GAATGGAGTA TCAGTGAGGA CAGTGGACCC
ACCCATGATG ACCCTCCATG CCTCACACAC ATCTATTACT CCCATGAAAA TCTGATCGAG
GATTTCAACT CGGGGCTGAT TGGGCCCCTG CTTATCTGTA AAAAAGGGAC CCTAACTGAG
GGTGGGACAC AGAAGACGTT TGACAAGCAA ATCGTGCTAC TATTTGCTGT GTTTGATGAA
AGCAAGAGCT GGAGCCAGTC ATCATCCCTA ATGTACACAG TCAATGGATA TGTGAATGGG
ACAATGCCAG ATATAACAGT TTGTGCCCAT GACCACATCA GCTGGCATCT GCTGGGAATG
AGCTCGGGGC CAGAATTATT CTCCATTCAT TTCAACGGCC AGGTCCTGGA GCAGAACCAT
CATAAGGTCT CAGCCATCAC CCTTGTCAGT GCTACATCCA CTACCGCAAA TATGACTGTG
GGCCCAGAGG GAAAGTGGAT CATATCTTCT CTCACCCCAA AACATTTGCA AGCTGGGATG
CAGGCTTACA TTGACATTAA AAACTGCCCA AAGAAAACCA GGAATCTTAA GAAAATAACT
CGTGAGCAGA GGCGGCACAT GAAGAGGTGG GAATACTTCA TTGCTGCAGA GGAAGTCATT
TGGGACTATG CACCTGTAAT ACCAGCGAAT ATGGACAAAA AATACAGGTC TCAGCATTTG
GATAATTTCT CAAACCAAAT TGGAAAACAT TATAAGAAAG TTATGTACAC ACAGTACGAA
GATGAGTCCT TCACCAAACA TACAGTGAAT CCCAATATGA AAGAAGATGG GATTTTGGGT
CCTATTATCA GAGCCCAGGT CAGAGACACA CTCAAAATCG TGTTCAAAAA TATGGCCAGC
CGCCCCTATA GCATTTACCC TCATGGAGTG ACCTTCTCGC CTTATGAAGA TGAAGTCAAC
TCTTCTTTCA CCTCAGGCAG GAACAACACC ATGATCAGAG CAGTTCAACC AGGGGAAACC
TATACTTATA AGTGGAACAT CTTAGAGTTT GATGAACCCA CAGAAAATGA TGCCCAGTGC
TTAACAAGAC CATACTACAG TGACGTGGAC ATCATGAGAG ACATCGCCTC TGGGCTAATA
GGACTACTTC TAATCTGTAA GAGCAGATCC CTGGACAGGC GAGGAATACA GAGGGCAGCA
GACATCGAAC AGCAGGCTGT GTTTGCTGTG TTTGATGAGA ACAAAAGCTG GTACCTTGAG
GACAACATCA ACAAGTTTTG TGAAAATCCT GATGAGGTGA AACGTGATGA CCCCAAGTTT
TATGAATCAA ACATCATGAG CACTATCAAT GGCTATGTGC CTGAGAGCAT AACTACTCTT
GGATTCTGCT TTGATGACAC TGTCCAGTGG CACTTCTGTA GTGTGGGGAC CCAGAATGAA
ATTTTGACCA TCCACTTCAC TGGGCACTCA TTCATCTATG GAAAGAGGCA TGAGGACACC
TTGACCCTCT TCCCCATGCG TGGAGAATCT GTGACGGTCA CAATGGATAA TGTTGGAACT
TGGATGTTAA CTTCCATGAA TTCTAGTCCA AGAAGCAAAA AGCTGAGGCT GAAATTCAGG
GATGTTAAAT GTATCCCAGA TGATGATGAA GACTCATATG AGATTTTTGA ACCTCCAGAA
TCTACAGTCA TGGCTACACG GAAAATGCAT GATCGTTTAG AACCTGAAGA TGAAGAGAGT
GATGCTGACT ATGATTACCA GAACAGACTG GCTGCAGCAT TAGGAATCAG GTCATTCCGA
AACTCATCAT TGAATCAGGA AGAAGAAGAG TTCAATCTTA CTGCCCTAGC TCTGGAGAAT
GGCACTGAAT TCGTTTCTTC AAACACAGAT ATAATTGTTG GTTCAAATTA TTCTTCCCCA
AGTAATATTA GTAAGTTCAC TGTCAATAAC CTTGCAGAAC CTCAGAAAGC CCCTTCTCAC
CAACAAGCCA CCACAGCTGG TTCCCCACTG AGACACCTCA TTGGCAAGAA CTCAGTTCTC
AATTCTTCCA CAGCAGAGCA TTCCAGCCCA TATTCTGAAG ACCCTATAGA GGATCCTCTA
CAGCCAGATG TCACAGGGAT ACGTCTACTT TCACTTGGTG CTGGAGAATT CAAAAGTCAA
GAACATGCTA AGCATAAGGG ACCCAAGGTA GAAAGAGATC AAGCAGCAAA GCACAGGTTC
TCCTGGATGA AATTACTAGC ACATAAAGTT GGGAGACACC TAAGCCAAGA CACTGGTTCT
CCTTCCGGAA TGAGGCCCTG GGAGGACCTT CCTAGCCAAG ACACTGGTTC TCCTTCCAGA
ATGAGGCCCT GGAAGGACCC TCCTAGTGAT CTGTTACTCT TAAAACAAAG TAACTCATCT
AAGATTTTGG TTGGGAGATG GCATTTGGCT TCTGAGAAAG GTAGCTATGA AATAATCCAA
GATACTGATG AAGACACAGC TGTTAACAAT TGGCTGATCA GCCCCCAGAA TGCCTCACGT
GCTTGGGGAG AAAGCACCCC TCTTGCCAAC AAGCCTGGAA AGCAGAGTGG CCACCCAAAG
TTTCCTAGAG TTAGACATAA ATCTCTACAA GTAAGACAGG ATGGAGGAAA GAGTAGACTG
AAGAAAAGCC AGTTTCTCAT TAAGACACGA AAAAAGAAAA AAGAGAAGCA CACACACCAT
GCTCCTTTAT CTCCGAGGAC CTTTCACCCT CTAAGAAGTG AAGCCTACAA CACATTTTCA
GAAAGAAGAC TTAAGCATTC GTTGGTGCTT CATAAATCCA ATGAAACATC TCTTCCCACA
GACCTCAATC AGACATTGCC CTCTATGGAT TTTGGCTGGA TAGCCTCACT TCCTGACCAT
AATCAGAATT CCTCAAATGA CACTGGTCAG GCAAGCTGTC CTCCAGGTCT TTATCAGACA
GTGCCCCCAG AGGAACACTA TCAAACATTC CCCATTCAAG ACCCTGATCA AATGCACTCT
ACTTCAGACC CCAGTCACAG ATCCTCTTCT CCAGAGCTCA GTGAAATGCT TGAGTATGAC
CGAAGTCACA AGTCCTTCCC CACAGATATA AGTCAAATGT CCCCTTCCTC AGAACATGAA
GTCTGGCAGA CAGTCATCTC TCCAGACCTC AGCCAGGTGA CCCTCTCTCC AGAACTCAGC
CAGACAAACC TCTCTCCAGA CCTCAGCCAC ACGACTCTCT CTCCAGAACT CATTCAGAGA
AACCTTTCCC CAGCCCTCGG TCAGATGCCC ATTTCTCCAG ACCTCAGCCA TACAACCCTT
TCTCCAGACC TCAGCCATAC AACCCTTTCT TTAGACCTCA GCCAGACAAA CCTCTCTCCA
GAACTCAGTC AGACAAACCT TTCTCCAGCC CTCGGTCAGA TGCCCCTTTC TCCAGACCTC
AGCCATACAA CCCTTTCTCT AGACTTCAGC CAGACAAACC TCTCTCCAGA ACTCAGCCAT
ATGACTCTCT CTCCAGAACT CAGTCAGACA AACCTTTCCC CAGCCCTCGG TCAGATGCCC
ATTTCTCCAG ACCTCAGCCA TACAACCCTT TCTCTAGACT TCAGCCAGAC AAACCTCTCT
CCAGAACTCA GTCAAACAAA CCTTTCCCCA GCCCTCGGTC AGATGCCCCT TTCTCCAGAC
CCCAGCCATA CAACCCTTTC TCTAGACCTC AGCCAGACAA ACCTCTCTCC AGAACTCAGT
CAGACAAACC TTTCCCCAGA CCTCAGTGAG ATGCCCCTCT TTGCAGATCT CAGTCAAATT
CCCCTTACCC CAGACCTCGA CCAGATGACA CTTTCTCCAG ACCTTGGTGA GACAGATCTT
TCCCCAAACT TTGGTCAGAT GTCCCTTTCC CCAGACCTCA GCCAGGTGAC TCTCTCTCCA
GACATCAGTG ACACCACCCT TCTCCCGGAT CTCAGCCAGA TATCACCTCC TCCAGACCTT
GATCAGATAT TCTACCCTTC TGAATCTAGT CAGTCATTGC TTCTTCAAGA ATTTAATGAG
TCTTTTCCTT ATCCAGACCT TGGTCAGATG CCATCTCCTT CATCTCCTAC TCTCAATGAT
ACTTTTCTAT CAAAGGAATT TAATCCACTG GTTATAGTGG GCCTCAGTAA AGATGGTACA
GATTACATTG AGATCATTCC AAAGGAAGAG GTCCAGAGCA GTGAAGATGA CTATGCTGAA
ATTGATTATG TGCCCTATGA TGACCCCTAC AAAACTGATG TTAGGACAAA CATCAACTCC
TCCAGAGATC CTGACAACAT TGCAGCATGG TACCTCCGCA GCAACAATGG AAACAGAAGA
AATTATTACA TTGCTGCTGA AGAAATATCC TGGGATTATT CAGAATTTGT ACAAAGGGAA
ACAGATATTG AAGACTCTGA TGATATTCCA GAAGATACCA CATATAAGAA AGTAGTTTTT
CGAAAGTACC TCGACAGCAC TTTTACCAAA CGTGATCCTC GAGGGGAGTA TGAAGAGCAT
CTCGGAATTC TTGGTCCTAT TATCAGAGCT GAAGTGGATG ATGTTATCCA AGTTCGTTTT
AAAAATTTAG CATCCAGACC GTATTCTCTA CATGCCCATG GACTTTCCTA TGAAAAATCA
TCAGAGGGAA AGACTTATGA AGATGACTCT CCTGAATGGT TTAAGGAAGA TAATGCTGTT
CAGCCAAATA GCAGTTATAC CTACGTATGG CATGCCACTG AGCGATCAGG GCCAGAAAGT
CCTGGCTCTG CCTGTCGGGC TTGGGCCTAC TACTCAGCTG TGAACCCAGA AAAAGATATT
CACTCAGGCT TGATAGGTCC CCTCCTAATC TGCCAAAAAG GAATACTACA TAAGGACAGC
AACATGCCTA TGGACATGAG AGAATTTGTC TTACTATTTA TGACCTTTGA TGAAAAGAAG
AGCTGGTACT ATGAAAAGAA GTCCCGAAGT TCTTGGAGAC TCACATCCTC AGAAATGAAA
AAATCCCATG AGTTTCACGC CATTAATGGG ATGATCTACA GCTTGCCTGG CCTGAAAATG
TATGAGCAAG AGTGGGTGAG GTTACACCTG CTGAACATAG GCGGCTCCCA AGACATTCAC
GTGGTTCACT TTCACGGCCA GACCTTGCTG GAAAATGGCA ATAAACAGCA CCAGTTAGGG
GTCTGGCCCC TTCTGCCTGG TTCATTTAAA ACTCTTGAAA TGAAGGCATC AAAACCTGGC
TGGTGGCTCC TAAACACAGA GGTTGGAGAA AACCAGAGAG CAGGGATGCA AACGCCATTT
CTTATCATGG ACAGAGACTG TAGGATGCCA ATGGGACTAA GCACTGGTAT CATATCTGAT
TCACAGATCA AGGCTTCAGA GTTTCTGGGT TACTGGGAGC CCAGATTAGC AAGATTAAAC
AATGGTGGAT CTTATAATGC TTGGAGTGTA GAAAAACTTG CAGCAGAATT TGCCTCTAAA
CCTTGGATCC AGGTGGACAT GCAAAAGGAA GTCATAATCA CAGGGATCCA GACCCAAGGT
GCCAAACACT ACCTGAAGTC CTGCTATACC ACAGAGTTCT ATGTAGCTTA CAGTTCCAAC
CAGATCAACT GGCAGATCTT CAAAGGGAAC AGCACAAGGA ATGTGATGTA TTTTAATGGC
AATTCAGATG CCTCTACAAT AAAAGAGAAT CAGTTTGACC CACCTATTGT GGCTAGATAT
ATTAGGATCT CTCCAACTCG AGCCTATAAC AGACCTACCC TTCGATTGGA ACTGCAAGGT
TGTGAGGTAA ATGGATGTTC CACACCCCTG GGTATGGAAA ATGGAAAGAT AGAAAACAAG
CAAATCACAG CTTCTTCGTT TAAGAAATCT TGGTGGGGAG ATTACTGGGA ACCCTTCCGT
GCCCGTCTGA ATGCCCAGGG ACGTGTGAAT GCCTGGCAAG CCAAGGCAAA CAACAATAAG
CAGTGGCTAG AAATTGATCT ACTCAAGATC AAGAAGATAA CGGCAATTAT AACACAGGGC
TGCAAGTCTC TGTCCTCTGA AATGTATGTA AAGAGCTATA CCATCCACTA CAGTGAGCAG
GGAGTGGAAT GGAAACCATA CAGGCTGAAA TCCTCCATGG TGGACAAGAT TTTTGAAGGA
AATACTAATA CCAAAGGACA TGTGAAGAAC TTTTTCAACC CCCCAATCAT TTCCAGGTTT
ATCCGTGTCA TTCCTAAAAC ATGGAATCAA AGTATTGCAC TTCGCCTGGA ACTCTTTGGC
TGTGATATTT ACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

The linker connecting the two kringles plays a key role in prothrombin activation
Proc. Natl. Acad. Sci. U.S.A. 111 (21), 7630-7635 (2014)
Pozzi N, Chen Z, Pelc LA, Shropshire DB and Di Cera E.


book

Phosphatidylserine and FVa regulate FXa structure
Biochem. J. 459 (1), 229-239 (2014)
Srivasatava KR, Majumder R, Kane WH, Quinn-Allen MA and Lentz BR.


book

Peripartum thromboprophylaxis for homozygous and heterozygous FVL mutation carriers yields similar pregnancy outcome
Isr. Med. Assoc. J. 16 (2), 96-100 (2014)
Gat,I., Dulitzki,M., Schiff,E., Sivan,E. and Simchen,M.J.


book

[The detection of Leiden mutation using technique of enzymatic extension of allele-specific primer with double bioluminescent detection (PED-Biolum)]
Klin. Lab. Diagn. 12, 26 (2013)
Krasitskaia,V.V., Subbotina,T.N., Ol'khovskii,I.A. and Frank,L.A.


book

Mesenteric vein thrombosis in a patient heterozygous for factor V Leiden and G20210A prothrombin genotypes
World J. Gastroenterol. 19 (43), 7813-7815 (2013)
Karmacharya P, Aryal MR and Donato A.


book

Factor V Leiden Thrombophilia
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Kujovich,J.L.


book

Structure of the gene for human coagulation factor V
Biochemistry 31 (15), 3777-3785 (1992)
Cripe LD, Moore KD and Kane WH.


book

A novel functional assay of protein C in human plasma and its comparison with amidolytic and anticoagulant assays
Thromb. Haemost. 67 (1), 46-49 (1992)
Guglielmone HA and Vides MA.


book

Sulfation of tyrosine residues in coagulation factor V
Blood 76 (5), 946-952 (1990)
Hortin GL.


book

Prothrombinase complex assembly. Contributions of protein-protein and protein-membrane interactions toward complex formation
J. Biol. Chem. 265 (7), 3708-3718 (1990)
Krishnaswamy S.


 
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