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FANCB cDNA ORF clone, Homo sapiens (human)

Gene Symbol FANCB
Entrez Gene ID 2187
Full Name Fanconi anemia, complementation group B
Synonyms FA2, FAAP90, FAAP95, FAB, FACB
General protein information
Preferred Names
Fanconi anemia group B protein
Names
Fanconi anemia group B protein
Fanconi anemia-associated polypeptide of 95 kDa
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp22.2

Summary The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

300515

Disorder Html: Fanconi anemia, complementation group B, 300514 (3)





The following FANCB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FANCB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu57691 XM_011545470 PREDICTED: Homo sapiens Fanconi anemia, complementation group B (FANCB), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu25772 NM_152633 Homo sapiens Fanconi anemia, complementation group B (FANCB), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu25772 NM_001018113 Homo sapiens Fanconi anemia, complementation group B (FANCB), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu57691
Accession Version XM_011545470.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2790bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product Fanconi anemia group B protein isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167197.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
ATGACTAGCA AACAAGCAAT GTCATCTAAC GAACAAGAAA GGCTCTTGTG TTATAATGGG 
GAAGTCCTTG TTTTCCAGTT GTCTAAAGGA AATTTTGCAG ATAAAGAGCC TACAAAAACA
CCCATATTAC ATGTCAGAAG AATGGTATTT GACAGAGGAA CAAAAGTATT TGTTCAGAAG
TCCACTGGAT TTTTTACCAT AAAGGAAGAA AACTCTCATT TAAAAATCAT GTGTTGCAAC
TGTGTGTCAG ATTTCAGAAC TGGAATTAAC CTCCCTTACA TTGTGATAGA AAAAAATAAA
AAGAATAATG TTTTTGAATA TTTTTTACTA ATCCTTCACA GTACTAATAA ATTTGAAATG
CGTTTGAGTT TTAAACTAGG CTATGAGATG AAGGATGGCC TAAGGGTCCT TAATGGCCCT
TTAATTTTAT GGAGGCATGT CAAAGCATTC TTCTTTATCT CTTCTCAAAC TGGCAAAGTT
GTTAGTGTGT CAGGTAACTT TTCCTCTATT CAGTGGGCAG GGGAGATTGA AAATTTAGGT
ATGGTTTTAT TGGGACTAAA GGAATGTTGT TTATCTGAGG AAGAATGTAC TCAAGAGCCT
TCAAAATCAG ATTATGCAAT TTGGAATACC AAATTTTGTG TATATTCTCT TGAAAGTCAA
GAAGTATTAA GTGATATATA CATTATTCCT CCTGCTTACA GCAGTGTGGT GACTTATGTA
CATATTTGTG CAACTGAGAT CATCAAAAAC CAGTTAAGAA TATCTCTCAT TGCCCTTACT
CGAAAGAATC AGCTGATTTC ATTTCAGAAT GGAACTCCTA AAAATGTGTG CCAGCTTCCA
TTTGGAGATC CTTGTGCAGT TCAACTTATG GATTCAGGTG GAGGAAACCT CTTTTTCGTT
GTATCCTTTA TATCCAATAA TGCTTGTGCT GTATGGAAAG AGAGCTTTCA GGTTGCTGCT
AAATGGGAAA AACTTAGCTT AGTACTGATA GATGACTTTA TTGGAAGTGG AACTGAACAA
GTACTCCTAC TTTTTAAGGA CTCCTTGAAC TCAGACTGCC TGACTTCATT TAAAATAACG
GATCTTGGAA AAATAAACTA TTCGAGTGAA CCATCAGATT GCAATGAAGA TGACTTATTT
GAAGACAAAC AAGAGAATCG TTACCTGGTG GTTCCACCTC TAGAAACAGG ACTGAAAGTT
TGTTTTTCTT CTTTTCGGGA ATTACGGCAG CATCTGTTGC TTAAGGAAAA AATTATTTCA
AAATCTTACA AAGCTTTAAT AAACCTAGTT CAAGGAAAAG ATGATAATAC GTCAAGTGCA
GAGGAGAAGG AATGTCTTGT TCCTCTTTGT GGTGAAGAAG AAAATTCTGT CCATATCTTA
GATGAAAAGT TATCAGACAA TTTTCAAGAT TCAGAACAGC TAGTAGAGAA GATATGGTAT
CGTGTAATAG ATGATAGCTT GGTTGTTGGA GTGAAAACTA CATCTTCTTT GAAGCTGTCC
CTGAATGATG TGACTTTATC ATTGTTAATG GATCAAGCCC ATGACTCCAG ATTTCGGCTT
CTAAAGTGTC AAAATAGGGT GATTAAGTTG AGTACAAATC CTTTCCCAGC ACCATACTTG
ATGCCATGTG AAATAGGATT GGAAGCAAAA AGGGTCACGT TGACCCCTGA TAGCAAGAAA
GAGGAAAGCT TTGTTTGTGA ACACCCATCT AAGAAAGAGT GTGTACAGAT AATTACTGCT
GTAACATCTC TTTCACCACT TTTAACATTC AGTAAATTTT GTTGCACTGT ACTGCTACAA
ATTATGGAGA GAGAAAGTGG TAACTGTCCT AAAGATCGTT ATGTTGTGTG TGGCAGAGTT
TTTTTAAGTC TAGAAGATCT TTCAACTGGG AAGTACCTAC TGACATTTCC AAAGAAGAAA
CCTATAGAGC ACATGGAAGA TCTTTTTGCA CTTCTTGCAG CATTCCATAA ATCTTGTTTT
CAAATCACAT CACCCGGCTA TGCCCTGAAT TCAATGAAGG TGTGGCTCTT AGAACATATG
AAATGTGAAA TAATCAAAGA ATTTCCAGAA GTGTACTTTT GTGAAAGACC GGGAAGTTTC
TATGGGACAC TCTTCACTTG GAAACAGAGA ACACCATTCG AAGGGATTTT AATAATCTAT
TCCAGGAATC AAACAGTTAT GTTCCAGTGC CTTCATAATC TCATCAGAAT TCTCCCTATA
AACTGTTTCC TCAAAAATCT AAAATCAGGA AGTGAGAATT TCCTAATTGA TAATATGGCA
TTTACTTTGG AGAAGGAACT AGTCACCCTT AGTTCTCTTT CTTCTGCCAT AGCTAAACAT
GAAAGCAATT TTATGCAGAG GTGTGAAGTG AGCAAAGGAA AGAGTAGTGT CGTCGCGGCT
GCTTTATCAG ACAGAAGGGA AAATATCCAT CCCTACAGAA AAGAACTTCA GAGAGAAAAG
AAGAAAATGT TGCAAACGAA CCTAAAAATC ACATGTTTTG GGGAAAGCCA GCCAACCTGC
CATGAGGACA CTCAAGCAGC CCTAGGAAGA GTCCTACCTT GCAAAGATCT GAGGCCTCCT
GCTAACAGCC AGCAAGGAAT TGAGAACTCC AACTGCCAGC TTTTGGGCTG GAATCAACAC
CACCAGCTCT CCTGGTTCTC AGGTCTTCAG ACTTGGACTG GAACTATATC ATTGGCTCTC
CTGGATCTCC AGCTTGCTGA CTGCAGATCT TGGGACTACT CAGCTTCGAT AATCATCCAC
GTTGGAAACC CCAGTCAAGC CTTCAGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011543772.1
CDS524..3313
Translation
Position Chain Variation Link
7 7 c, g dbSNP:779184908
46 46 c, g dbSNP:755313509
57 57 c, t dbSNP:369899568
182 182 a, c dbSNP:2285490
233 233 c, t dbSNP:767153088
250 250 c, g dbSNP:557809156
292 292 a, g dbSNP:756766337
295 295 g, t dbSNP:149617434
305 305 c, g dbSNP:373175926
351 351 c, g dbSNP:2188383
355 355 g, t dbSNP:749253187
377 377 c, t dbSNP:779976534
397 397 c, t dbSNP:755929895
413 413 a, g, t dbSNP:185118376
445 445 a, g dbSNP:180836371
464 464 a, g dbSNP:766037619
474 474 a, g dbSNP:113427280
490 490 a, c dbSNP:746305258
497 497 a, g dbSNP:779269252
503 503 a, g dbSNP:771221018
510 510 c, t dbSNP:749284903
518 518 a, t dbSNP:777928160
519 519 a, g dbSNP:754812432
530 530 a, g dbSNP:139111718
531 531 g, t dbSNP:751501999
539 539 c, t dbSNP:5935815
540 540 a, c dbSNP:780032769
545 545 c, t dbSNP:758176689
553 553 a, c, g dbSNP:750078094
554 554 a, g dbSNP:370199124
564 564 a, g dbSNP:753239814
567 567 c, t dbSNP:368686910
577 577 c, t dbSNP:763676399
590 590 c, g dbSNP:761024549
592 592 c, t dbSNP:151173533
598 598 a, c dbSNP:772767612
616 616 c, t dbSNP:759943598
620 620 g, t dbSNP:774883903
650 650 a, t dbSNP:771007866
661 661 a, g dbSNP:749536805
676 676 c, t dbSNP:777646355
677 677 a, g dbSNP:769911209
685 685 a, g dbSNP:748284861
686 686 a, g dbSNP:779944907
717 717 a, t dbSNP:758372962
720 720 c, t dbSNP:750180189
722 722 a, g dbSNP:761346761
747 747 a, c dbSNP:756804647
753 753 c, t dbSNP:753536320
759 759 c, g dbSNP:763724576
785 785 a, g dbSNP:142101123
794 794 c, g dbSNP:752308987
796 796 c, t dbSNP:768094187
813 813 a, g dbSNP:760139481
830 830 a, g dbSNP:776604406
853 853 a, c dbSNP:201633684
884 884 c, t dbSNP:145928137
885 885 a, g dbSNP:142289802
891 891 g, t dbSNP:773468741
904 904 c, t dbSNP:769958914
910 910 c, g dbSNP:748195117
911 911 a, g dbSNP:776724055
913 913 a, g dbSNP:771949781
925 925 a, g dbSNP:147260208
937 937 a, t dbSNP:201281219
963 963 c, t dbSNP:757074045
981 981 a, t dbSNP:749099779
987 987 c, t dbSNP:777463253
988 988 c, t dbSNP:755858770
1016 1016 c, g dbSNP:146131050
1027 1027 c, g dbSNP:373738816
1030 1030 c, t dbSNP:149609970
1031 1031 a, c, g dbSNP:138251388
1033 1033 g, t dbSNP:775216604
1036 1036 a, g dbSNP:763353362
1051 1051 g, t dbSNP:773488727
1067 1067 g, t dbSNP:765459332
1075 1075 a, g dbSNP:771998496
1077 1077 g, t dbSNP:776636177
1083 1083 a, g dbSNP:768729913
1107 1107 a, g dbSNP:747162028
1114 1114 g, t dbSNP:774337829
1118 1118 a, g dbSNP:749426439
1136 1136 g, t dbSNP:749082728
1138 1138 c, t dbSNP:777464540
1161 1161 g, t dbSNP:755764501
1175 1175 c, g dbSNP:747819351
1176 1176 a, c dbSNP:781051710
1177 1177 a, c dbSNP:780311940
1182 1182 a, g dbSNP:751071983
1189 1189 a, g dbSNP:766888316
1204 1204 c, t dbSNP:370365613
1211 1211 c, t dbSNP:200970121
1223 1223 a, g dbSNP:750759993
1225 1225 c, t dbSNP:201709202
1229 1229 a, g dbSNP:746389250
1234 1234 a, g dbSNP:754044680
1252 1252 c, t dbSNP:186168143
1258 1258 c, t dbSNP:181962343
1264 1264 a, c dbSNP:760773732
1267 1267 a, c dbSNP:199762452
1276 1276 a, g dbSNP:775476952
1295 1295 g, t dbSNP:770865662
1311 1311 a, c dbSNP:762806947
1323 1323 c, t dbSNP:374217132
1324 1324 a, c dbSNP:773005941
1337 1337 a, g dbSNP:769701122
1344 1344 a, t dbSNP:748024447
1356 1356 a, g dbSNP:150435015
1363 1363 a, g dbSNP:112467543
1381 1381 a, g dbSNP:768472627
1387 1387 a, g dbSNP:746479455
1392 1392 c, t dbSNP:754552650
1412 1412 c, t dbSNP:758872342
1415 1415 c, t dbSNP:750905901
1420 1420 c, t dbSNP:753443421
1421 1421 a, g dbSNP:757610875
1433 1433 a, g dbSNP:754238911
1435 1435 a, g dbSNP:765890822
1439 1439 a, g dbSNP:764274377
1440 1440 a, g dbSNP:760825817
1452 1452 c, g dbSNP:752759773
1457 1457 c, t dbSNP:141443393
1462 1462 a, g dbSNP:767512088
1467 1467 c, g dbSNP:759722195
1483 1483 g, t dbSNP:139045247
1484 1484 a, g dbSNP:771467972
1512 1512 c, t dbSNP:200161949
1527 1527 a, g dbSNP:41309679
1572 1572 a, c dbSNP:757806819
1583 1583 c, g dbSNP:754149022
1590 1590 c, t dbSNP:142304943
1600 1600 a, t dbSNP:191379403
1602 1602 c, t dbSNP:138192474
1603 1603 a, c, g dbSNP:754983238
1621 1621 c, g dbSNP:369863081
1626 1626 c, t dbSNP:143585647
1627 1627 a, g dbSNP:761873562
1630 1630 g, t dbSNP:756433447
1636 1636 a, g dbSNP:748588943
1643 1643 c, t dbSNP:781251036
1654 1654 g, t dbSNP:148882589
1663 1663 a, t dbSNP:199909156
1671 1671 a, g dbSNP:376945933
1672 1672 a, g dbSNP:751649474
1682 1682 c, t dbSNP:145542355
1683 1683 a, g dbSNP:757202355
1700 1700 c, t dbSNP:753812355
1702 1702 c, t dbSNP:764156696
1731 1731 c, t dbSNP:747247621
1738 1738 a, g, t dbSNP:758546007
1748 1748 c, t dbSNP:750569208
1749 1749 a, g dbSNP:753030842
1757 1757 c, t dbSNP:765480337
1773 1773 a, c dbSNP:752391089
1779 1779 c, t dbSNP:759581894
1786 1786 a, g dbSNP:759388298
1790 1790 c, t dbSNP:776805534
1812 1812 c, t dbSNP:376384388
1831 1831 c, t dbSNP:762430531
1833 1833 c, t dbSNP:772802668
1834 1834 a, g, t dbSNP:762387195
1840 1840 g, t dbSNP:776802337
1854 1854 a, g, t dbSNP:368679125
1868 1868 c, g dbSNP:781260236
1872 1872 a, g dbSNP:764817410
1877 1877 a, g dbSNP:761286423
1881 1881 a, g dbSNP:777190282
1894 1894 c, t dbSNP:149695930
1896 1896 a, g dbSNP:140773512
1913 1913 c, t dbSNP:146438837
1916 1916 c, t dbSNP:143976596
1925 1925 a, t dbSNP:374559250
1929 1929 a, t dbSNP:746103110
1945 1945 a, g dbSNP:778796466
1949 1949 a, g dbSNP:372644335
1965 1965 a, g dbSNP:140198444
1978 1978 g, t dbSNP:781087988
2006 2006 a, t dbSNP:754933644
2016 2016 a, g dbSNP:746768201
2017 2017 g, t dbSNP:199510538
2032 2032 c, t dbSNP:775926751
2072 2072 a, g dbSNP:768004295
2075 2075 a, t dbSNP:373632536
2093 2093 c, g dbSNP:370248837
2104 2104 g, t dbSNP:758665871
2105 2105 a, g dbSNP:749342600
2129 2129 c, t dbSNP:773313492
2133 2133 c, t dbSNP:752804063
2134 2134 a, g dbSNP:746962101
2137 2137 a, g dbSNP:780024809
2141 2141 g, t dbSNP:144205393
2157 2157 c, t dbSNP:745690135
2159 2159 a, g dbSNP:778604488
2160 2160 c, g dbSNP:756880603
2161 2161 a, t dbSNP:753355273
2163 2163 c, t dbSNP:763699754
2169 2169 a, c dbSNP:756628396
2181 2181 c, t dbSNP:146157131
2182 2182 a, g dbSNP:767952529
2206 2206 a, g dbSNP:759926657
2211 2211 g, t dbSNP:375901101
2224 2224 a, g dbSNP:766587734
2225 2225 c, t dbSNP:763091316
2242 2242 g, t dbSNP:773221142
2243 2243 a, c, t dbSNP:200303151
2249 2249 c, g dbSNP:775375428
2259 2259 c, t dbSNP:771950360
2268 2268 c, t dbSNP:754392611
2277 2277 c, t dbSNP:772448306
2278 2278 a, g dbSNP:745472535
2279 2279 a, c dbSNP:770548473
2282 2282 c, g dbSNP:748958265
2292 2292 c, t dbSNP:142959373
2309 2309 a, g dbSNP:756702783
2311 2311 c, t dbSNP:752308935
2334 2334 c, g dbSNP:781690574
2340 2340 a, g dbSNP:148560784
2357 2357 a, g dbSNP:751885600
2361 2361 a, g dbSNP:144764663
2364 2364 a, g dbSNP:763366953
2369 2369 c, g dbSNP:750639868
2417 2417 g, t dbSNP:149387792
2423 2423 c, t dbSNP:200948146
2435 2435 a, g dbSNP:776713934
2438 2438 a, g dbSNP:772005838
2447 2447 a, g dbSNP:370765798
2453 2453 c, t dbSNP:772271125
2482 2482 a, g dbSNP:751996827
2510 2510 a, g dbSNP:184796918
2518 2518 c, t dbSNP:192743430
2519 2519 a, g dbSNP:145110602
2523 2523 a, g dbSNP:745346114
2538 2538 c, t dbSNP:377268147
2549 2549 c, t dbSNP:753885194
2576 2576 a, g dbSNP:764091042
2594 2594 a, g dbSNP:760863919
2595 2595 c, t dbSNP:187737855
2607 2607 a, g dbSNP:771044033
2613 2613 c, t dbSNP:147255018
2614 2614 a, g dbSNP:540569670
2616 2616 a, g dbSNP:773176825
2623 2623 a, c dbSNP:769508299
2625 2625 a, g dbSNP:746890051
2649 2649 a, c dbSNP:776403333
2653 2653 a, g dbSNP:768048579
2669 2669 a, t dbSNP:373141774
2674 2674 a, t dbSNP:143850231
2678 2678 a, t dbSNP:746571415
2680 2680 c, g dbSNP:138268044
2682 2682 a, g dbSNP:758926056
2694 2694 a, g dbSNP:371428199
2696 2696 a, g dbSNP:765112491
2699 2699 a, g dbSNP:777566944
2710 2710 a, g dbSNP:776118523
2718 2718 a, g dbSNP:768405501
2741 2741 a, g dbSNP:746453967
2745 2745 a, t dbSNP:771958941
2751 2751 c, g, t dbSNP:747865842
2752 2752 a, c dbSNP:201070097
2761 2761 c, t dbSNP:779449906
2767 2767 a, g dbSNP:757610874
2775 2775 a, g dbSNP:749699443
2788 2788 a, g dbSNP:777812135
2790 2790 a, t dbSNP:756392097
2799 2799 c, t dbSNP:752657026
2816 2816 a, g dbSNP:767721906
2826 2826 a, t dbSNP:755167575
2834 2834 a, g dbSNP:750381270
2845 2845 g, t dbSNP:765307016
2850 2850 c, t dbSNP:761492600
2852 2852 a, c dbSNP:776505971
2862 2862 a, g dbSNP:150377883
2864 2864 -, a dbSNP:35806617
2865 2865 a, g dbSNP:140363445
2901 2901 a, g dbSNP:377742035
2914 2914 a, c, t dbSNP:778731279
2917 2917 c, t dbSNP:190579053
2918 2918 a, g dbSNP:368933083
2920 2920 -, ggctgc dbSNP:749454699
2920 2920 a, g dbSNP:746293753
2925 2925 c, g dbSNP:749578530
2934 2934 a, g dbSNP:148257882
2958 2958 a, g dbSNP:780116069
2962 2962 a, g dbSNP:748392793
2964 2964 a, g dbSNP:200325876
2975 2975 a, g dbSNP:143131218
2990 2990 a, t dbSNP:755077854
3000 3000 c, t dbSNP:201436396
3001 3001 a, g dbSNP:778946615
3008 3008 a, g dbSNP:373465821
3040 3040 c, g dbSNP:779156584
3067 3067 a, g dbSNP:747204453
3068 3068 a, g dbSNP:778048999
3110 3110 a, g dbSNP:189863710
3115 3115 a, g dbSNP:116550115
3139 3139 c, t dbSNP:754257299
3150 3150 a, g dbSNP:7053178
3215 3215 c, t dbSNP:752613260
3283 3283 c, t dbSNP:778843362
3285 3285 c, t dbSNP:575282660
3302 3302 c, g dbSNP:564111538
3303 3303 c, g dbSNP:113207254
3330 3330 a, c dbSNP:749761254
3354 3354 a, g dbSNP:180847041

Target ORF information:

RefSeq Version XM_011545470
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens Fanconi anemia, complementation group B (FANCB), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545470

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
ATGACTAGCA AACAAGCAAT GTCATCTAAC GAACAAGAAA GGCTCTTGTG TTATAATGGG 
GAAGTCCTTG TTTTCCAGTT GTCTAAAGGA AATTTTGCAG ATAAAGAGCC TACAAAAACA
CCCATATTAC ATGTCAGAAG AATGGTATTT GACAGAGGAA CAAAAGTATT TGTTCAGAAG
TCCACTGGAT TTTTTACCAT AAAGGAAGAA AACTCTCATT TAAAAATCAT GTGTTGCAAC
TGTGTGTCAG ATTTCAGAAC TGGAATTAAC CTCCCTTACA TTGTGATAGA AAAAAATAAA
AAGAATAATG TTTTTGAATA TTTTTTACTA ATCCTTCACA GTACTAATAA ATTTGAAATG
CGTTTGAGTT TTAAACTAGG CTATGAGATG AAGGATGGCC TAAGGGTCCT TAATGGCCCT
TTAATTTTAT GGAGGCATGT CAAAGCATTC TTCTTTATCT CTTCTCAAAC TGGCAAAGTT
GTTAGTGTGT CAGGTAACTT TTCCTCTATT CAGTGGGCAG GGGAGATTGA AAATTTAGGT
ATGGTTTTAT TGGGACTAAA GGAATGTTGT TTATCTGAGG AAGAATGTAC TCAAGAGCCT
TCAAAATCAG ATTATGCAAT TTGGAATACC AAATTTTGTG TATATTCTCT TGAAAGTCAA
GAAGTATTAA GTGATATATA CATTATTCCT CCTGCTTACA GCAGTGTGGT GACTTATGTA
CATATTTGTG CAACTGAGAT CATCAAAAAC CAGTTAAGAA TATCTCTCAT TGCCCTTACT
CGAAAGAATC AGCTGATTTC ATTTCAGAAT GGAACTCCTA AAAATGTGTG CCAGCTTCCA
TTTGGAGATC CTTGTGCAGT TCAACTTATG GATTCAGGTG GAGGAAACCT CTTTTTCGTT
GTATCCTTTA TATCCAATAA TGCTTGTGCT GTATGGAAAG AGAGCTTTCA GGTTGCTGCT
AAATGGGAAA AACTTAGCTT AGTACTGATA GATGACTTTA TTGGAAGTGG AACTGAACAA
GTACTCCTAC TTTTTAAGGA CTCCTTGAAC TCAGACTGCC TGACTTCATT TAAAATAACG
GATCTTGGAA AAATAAACTA TTCGAGTGAA CCATCAGATT GCAATGAAGA TGACTTATTT
GAAGACAAAC AAGAGAATCG TTACCTGGTG GTTCCACCTC TAGAAACAGG ACTGAAAGTT
TGTTTTTCTT CTTTTCGGGA ATTACGGCAG CATCTGTTGC TTAAGGAAAA AATTATTTCA
AAATCTTACA AAGCTTTAAT AAACCTAGTT CAAGGAAAAG ATGATAATAC GTCAAGTGCA
GAGGAGAAGG AATGTCTTGT TCCTCTTTGT GGTGAAGAAG AAAATTCTGT CCATATCTTA
GATGAAAAGT TATCAGACAA TTTTCAAGAT TCAGAACAGC TAGTAGAGAA GATATGGTAT
CGTGTAATAG ATGATAGCTT GGTTGTTGGA GTGAAAACTA CATCTTCTTT GAAGCTGTCC
CTGAATGATG TGACTTTATC ATTGTTAATG GATCAAGCCC ATGACTCCAG ATTTCGGCTT
CTAAAGTGTC AAAATAGGGT GATTAAGTTG AGTACAAATC CTTTCCCAGC ACCATACTTG
ATGCCATGTG AAATAGGATT GGAAGCAAAA AGGGTCACGT TGACCCCTGA TAGCAAGAAA
GAGGAAAGCT TTGTTTGTGA ACACCCATCT AAGAAAGAGT GTGTACAGAT AATTACTGCT
GTAACATCTC TTTCACCACT TTTAACATTC AGTAAATTTT GTTGCACTGT ACTGCTACAA
ATTATGGAGA GAGAAAGTGG TAACTGTCCT AAAGATCGTT ATGTTGTGTG TGGCAGAGTT
TTTTTAAGTC TAGAAGATCT TTCAACTGGG AAGTACCTAC TGACATTTCC AAAGAAGAAA
CCTATAGAGC ACATGGAAGA TCTTTTTGCA CTTCTTGCAG CATTCCATAA ATCTTGTTTT
CAAATCACAT CACCCGGCTA TGCCCTGAAT TCAATGAAGG TGTGGCTCTT AGAACATATG
AAATGTGAAA TAATCAAAGA ATTTCCAGAA GTGTACTTTT GTGAAAGACC GGGAAGTTTC
TATGGGACAC TCTTCACTTG GAAACAGAGA ACACCATTCG AAGGGATTTT AATAATCTAT
TCCAGGAATC AAACAGTTAT GTTCCAGTGC CTTCATAATC TCATCAGAAT TCTCCCTATA
AACTGTTTCC TCAAAAATCT AAAATCAGGA AGTGAGAATT TCCTAATTGA TAATATGGCA
TTTACTTTGG AGAAGGAACT AGTCACCCTT AGTTCTCTTT CTTCTGCCAT AGCTAAACAT
GAAAGCAATT TTATGCAGAG GTGTGAAGTG AGCAAAGGAA AGAGTAGTGT CGTCGCGGCT
GCTTTATCAG ACAGAAGGGA AAATATCCAT CCCTACAGAA AAGAACTTCA GAGAGAAAAG
AAGAAAATGT TGCAAACGAA CCTAAAAATC ACATGTTTTG GGGAAAGCCA GCCAACCTGC
CATGAGGACA CTCAAGCAGC CCTAGGAAGA GTCCTACCTT GCAAAGATCT GAGGCCTCCT
GCTAACAGCC AGCAAGGAAT TGAGAACTCC AACTGCCAGC TTTTGGGCTG GAATCAACAC
CACCAGCTCT CCTGGTTCTC AGGTCTTCAG ACTTGGACTG GAACTATATC ATTGGCTCTC
CTGGATCTCC AGCTTGCTGA CTGCAGATCT TGGGACTACT CAGCTTCGAT AATCATCCAC
GTTGGAAACC CCAGTCAAGC CTTCAGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25772
Accession Version NM_152633.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2580bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product Fanconi anemia group B protein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK091383.1. On May 24, 2005 this sequence version replaced gi:22749292. Summary: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: An upstream start codon is used for this RefSeq based on conservation in at least 10 vertebrate species including human, chimp, rhesus, treeshrew, guinea pig, rabbit, hedgehog, dog, horse and armadillo. In the literature (PubMed ID: 15502827), a start codon that is 6 aa downstream has been used as the translation AUG start codon based on conservation with mouse and chicken. No experimental evidence exists regarding which site is preferentially used. Also, no predicted N-terminal domains or signal peptides for either the longer or shorter proteins exist. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK091383.1, BC136560.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2152719 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
ATGACTAGCA AACAAGCAAT GTCATCTAAC GAACAAGAAA GGCTCTTGTG TTATAATGGG 
GAAGTCCTTG TTTTCCAGTT GTCTAAAGGA AATTTTGCAG ATAAAGAGCC TACAAAAACA
CCCATATTAC ATGTCAGAAG AATGGTATTT GACAGAGGAA CAAAAGTATT TGTTCAGAAG
TCCACTGGAT TTTTTACCAT AAAGGAAGAA AACTCTCATT TAAAAATCAT GTGTTGCAAC
TGTGTGTCAG ATTTCAGAAC TGGAATTAAC CTCCCTTACA TTGTGATAGA AAAAAATAAA
AAGAATAATG TTTTTGAATA TTTTTTACTA ATCCTTCACA GTACTAATAA ATTTGAAATG
CGTTTGAGTT TTAAACTAGG CTATGAGATG AAGGATGGCC TAAGGGTCCT TAATGGCCCT
TTAATTTTAT GGAGGCATGT CAAAGCATTC TTCTTTATCT CTTCTCAAAC TGGCAAAGTT
GTTAGTGTGT CAGGTAACTT TTCCTCTATT CAGTGGGCAG GGGAGATTGA AAATTTAGGT
ATGGTTTTAT TGGGACTAAA GGAATGTTGT TTATCTGAGG AAGAATGTAC TCAAGAGCCT
TCAAAATCAG ATTATGCAAT TTGGAATACC AAATTTTGTG TATATTCTCT TGAAAGTCAA
GAAGTATTAA GTGATATATA CATTATTCCT CCTGCTTACA GCAGTGTGGT GACTTATGTA
CATATTTGTG CAACTGAGAT CATCAAAAAC CAGTTAAGAA TATCTCTCAT TGCCCTTACT
CGAAAGAATC AGCTGATTTC ATTTCAGAAT GGAACTCCTA AAAATGTGTG CCAGCTTCCA
TTTGGAGATC CTTGTGCAGT TCAACTTATG GATTCAGGTG GAGGAAACCT CTTTTTCGTT
GTATCCTTTA TATCCAATAA TGCTTGTGCT GTATGGAAAG AGAGCTTTCA GGTTGCTGCT
AAATGGGAAA AACTTAGCTT AGTACTGATA GATGACTTTA TTGGAAGTGG AACTGAACAA
GTACTCCTAC TTTTTAAGGA CTCCTTGAAC TCAGACTGCC TGACTTCATT TAAAATAACG
GATCTTGGAA AAATAAACTA TTCGAGTGAA CCATCAGATT GCAATGAAGA TGACTTATTT
GAAGACAAAC AAGAGAATCG TTACCTGGTG GTTCCACCTC TAGAAACAGG ACTGAAAGTT
TGTTTTTCTT CTTTTCGGGA ATTACGGCAG CATCTGTTGC TTAAGGAAAA AATTATTTCA
AAATCTTACA AAGCTTTAAT AAACCTAGTT CAAGGAAAAG ATGATAATAC GTCAAGTGCA
GAGGAGAAGG AATGTCTTGT TCCTCTTTGT GGTGAAGAAG AAAATTCTGT CCATATCTTA
GATGAAAAGT TATCAGACAA TTTTCAAGAT TCAGAACAGC TAGTAGAGAA GATATGGTAT
CGTGTAATAG ATGATAGCTT GGTTGTTGGA GTGAAAACTA CATCTTCTTT GAAGCTGTCC
CTGAATGATG TGACTTTATC ATTGTTAATG GATCAAGCCC ATGACTCCAG ATTTCGGCTT
CTAAAGTGTC AAAATAGGGT GATTAAGTTG AGTACAAATC CTTTCCCAGC ACCATACTTG
ATGCCATGTG AAATAGGATT GGAAGCAAAA AGGGTCACGT TGACCCCTGA TAGCAAGAAA
GAGGAAAGCT TTGTTTGTGA ACACCCATCT AAGAAAGAGT GTGTACAGAT AATTACTGCT
GTAACATCTC TTTCACCACT TTTAACATTC AGTAAATTTT GTTGCACTGT ACTGCTACAA
ATTATGGAGA GAGAAAGTGG TAACTGTCCT AAAGATCGTT ATGTTGTGTG TGGCAGAGTT
TTTTTAAGTC TAGAAGATCT TTCAACTGGG AAGTACCTAC TGACATTTCC AAAGAAGAAA
CCTATAGAGC ACATGGAAGA TCTTTTTGCA CTTCTTGCAG CATTCCATAA ATCTTGTTTT
CAAATCACAT CACCCGGCTA TGCCCTGAAT TCAATGAAGG TGTGGCTCTT AGAACATATG
AAATGTGAAA TAATCAAAGA ATTTCCAGAA GTGTACTTTT GTGAAAGACC GGGAAGTTTC
TATGGGACAC TCTTCACTTG GAAACAGAGA ACACCATTCG AAGGGATTTT AATAATCTAT
TCCAGGAATC AAACAGTTAT GTTCCAGTGC CTTCATAATC TCATCAGAAT TCTCCCTATA
AACTGTTTCC TCAAAAATCT AAAATCAGGA AGTGAGAATT TCCTAATTGA TAATATGGCA
TTTACTTTGG AGAAGGAACT AGTCACCCTT AGTTCTCTTT CTTCTGCCAT AGCTAAACAT
GAAAGCAATT TTATGCAGAG GTGTGAAGTG AGCAAAGGAA AGAGTAGTGT CGTCGCGGCT
GCTTTATCAG ACAGAAGGGA AAATATCCAT CCCTACAGAA AAGAACTTCA GAGAGAAAAG
AAGAAAATGT TGCAAACGAA CCTAAAAGTG AGTGGTGCCC TTTACAGAGA AATAACTTTG
AAAGTAGCTG AGGTTCAGTT GAAATCAGAC TTTGCTGCAC AGAAACTGAG TAATTTATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_689846.1
CDS148..2727
Misc Feature(1)136..138(+)
Misc Feature(2)151..153(+)
Misc Feature(3)166..168(+)
Exon (1)1..77
Gene:FANCB
Gene Synonym:
Exon (2)78..1098
Gene:FANCB
Gene Synonym:
Exon (3)1099..1251
Gene:FANCB
Gene Synonym:
Exon (4)1252..1344
Gene:FANCB
Gene Synonym:
Exon (5)1345..1473
Gene:FANCB
Gene Synonym:
Exon (6)1474..1643
Gene:FANCB
Gene Synonym:
Exon (7)1644..2074
Gene:FANCB
Gene Synonym:
Exon (8)2075..2312
Gene:FANCB
Gene Synonym:
Exon (9)2313..2887
Gene:FANCB
Gene Synonym:
Translation
Position Chain Variation Link
37 37 a, g dbSNP:756766337
40 40 g, t dbSNP:149617434
50 50 c, g dbSNP:373175926
88 88 a, g dbSNP:766037619
98 98 a, g dbSNP:113427280
114 114 a, c dbSNP:746305258
121 121 a, g dbSNP:779269252
127 127 a, g dbSNP:771221018
134 134 c, t dbSNP:749284903
142 142 a, t dbSNP:777928160
143 143 a, g dbSNP:754812432
154 154 a, g dbSNP:139111718
155 155 g, t dbSNP:751501999
163 163 c, t dbSNP:5935815
164 164 a, c dbSNP:780032769
169 169 c, t dbSNP:758176689
177 177 a, c, g dbSNP:750078094
178 178 a, g dbSNP:370199124
188 188 a, g dbSNP:753239814
191 191 c, t dbSNP:368686910
201 201 c, t dbSNP:763676399
214 214 c, g dbSNP:761024549
216 216 c, t dbSNP:151173533
222 222 a, c dbSNP:772767612
240 240 c, t dbSNP:759943598
244 244 g, t dbSNP:774883903
274 274 a, t dbSNP:771007866
285 285 a, g dbSNP:749536805
300 300 c, t dbSNP:777646355
301 301 a, g dbSNP:769911209
309 309 a, g dbSNP:748284861
310 310 a, g dbSNP:779944907
341 341 a, t dbSNP:758372962
344 344 c, t dbSNP:750180189
346 346 a, g dbSNP:761346761
371 371 a, c dbSNP:756804647
377 377 c, t dbSNP:753536320
383 383 c, g dbSNP:763724576
409 409 a, g dbSNP:142101123
418 418 c, g dbSNP:752308987
420 420 c, t dbSNP:768094187
437 437 a, g dbSNP:760139481
454 454 a, g dbSNP:776604406
477 477 a, c dbSNP:201633684
508 508 c, t dbSNP:145928137
509 509 a, g dbSNP:142289802
515 515 g, t dbSNP:773468741
528 528 c, t dbSNP:769958914
534 534 c, g dbSNP:748195117
535 535 a, g dbSNP:776724055
537 537 a, g dbSNP:771949781
549 549 a, g dbSNP:147260208
561 561 a, t dbSNP:201281219
587 587 c, t dbSNP:757074045
605 605 a, t dbSNP:749099779
611 611 c, t dbSNP:777463253
612 612 c, t dbSNP:755858770
640 640 c, g dbSNP:146131050
651 651 c, g dbSNP:373738816
654 654 c, t dbSNP:149609970
655 655 a, c, g dbSNP:138251388
657 657 g, t dbSNP:775216604
660 660 a, g dbSNP:763353362
675 675 g, t dbSNP:773488727
691 691 g, t dbSNP:765459332
699 699 a, g dbSNP:771998496
701 701 g, t dbSNP:776636177
707 707 a, g dbSNP:768729913
731 731 a, g dbSNP:747162028
738 738 g, t dbSNP:774337829
742 742 a, g dbSNP:749426439
760 760 g, t dbSNP:749082728
762 762 c, t dbSNP:777464540
785 785 g, t dbSNP:755764501
799 799 c, g dbSNP:747819351
800 800 a, c dbSNP:781051710
801 801 a, c dbSNP:780311940
806 806 a, g dbSNP:751071983
813 813 a, g dbSNP:766888316
828 828 c, t dbSNP:370365613
835 835 c, t dbSNP:200970121
847 847 a, g dbSNP:750759993
849 849 c, t dbSNP:201709202
853 853 a, g dbSNP:746389250
858 858 a, g dbSNP:754044680
876 876 c, t dbSNP:186168143
882 882 c, t dbSNP:181962343
888 888 a, c dbSNP:760773732
891 891 a, c dbSNP:199762452
900 900 a, g dbSNP:775476952
919 919 g, t dbSNP:770865662
935 935 a, c dbSNP:762806947
947 947 c, t dbSNP:374217132
948 948 a, c dbSNP:773005941
961 961 a, g dbSNP:769701122
968 968 a, t dbSNP:748024447
980 980 a, g dbSNP:150435015
987 987 a, g dbSNP:112467543
1005 1005 a, g dbSNP:768472627
1011 1011 a, g dbSNP:746479455
1016 1016 c, t dbSNP:754552650
1036 1036 c, t dbSNP:758872342
1039 1039 c, t dbSNP:750905901
1044 1044 c, t dbSNP:753443421
1045 1045 a, g dbSNP:757610875
1057 1057 a, g dbSNP:754238911
1059 1059 a, g dbSNP:765890822
1063 1063 a, g dbSNP:764274377
1064 1064 a, g dbSNP:760825817
1076 1076 c, g dbSNP:752759773
1081 1081 c, t dbSNP:141443393
1086 1086 a, g dbSNP:767512088
1091 1091 c, g dbSNP:759722195
1107 1107 g, t dbSNP:139045247
1108 1108 a, g dbSNP:771467972
1136 1136 c, t dbSNP:200161949
1151 1151 a, g dbSNP:41309679
1196 1196 a, c dbSNP:757806819
1207 1207 c, g dbSNP:754149022
1214 1214 c, t dbSNP:142304943
1224 1224 a, t dbSNP:191379403
1226 1226 c, t dbSNP:138192474
1227 1227 a, c, g dbSNP:754983238
1245 1245 c, g dbSNP:369863081
1250 1250 c, t dbSNP:143585647
1251 1251 a, g dbSNP:761873562
1254 1254 g, t dbSNP:756433447
1260 1260 a, g dbSNP:748588943
1267 1267 c, t dbSNP:781251036
1278 1278 g, t dbSNP:148882589
1287 1287 a, t dbSNP:199909156
1295 1295 a, g dbSNP:376945933
1296 1296 a, g dbSNP:751649474
1306 1306 c, t dbSNP:145542355
1307 1307 a, g dbSNP:757202355
1324 1324 c, t dbSNP:753812355
1326 1326 c, t dbSNP:764156696
1355 1355 c, t dbSNP:747247621
1362 1362 a, g, t dbSNP:758546007
1372 1372 c, t dbSNP:750569208
1373 1373 a, g dbSNP:753030842
1381 1381 c, t dbSNP:765480337
1397 1397 a, c dbSNP:752391089
1403 1403 c, t dbSNP:759581894
1410 1410 a, g dbSNP:759388298
1414 1414 c, t dbSNP:776805534
1436 1436 c, t dbSNP:376384388
1455 1455 c, t dbSNP:762430531
1457 1457 c, t dbSNP:772802668
1458 1458 a, g, t dbSNP:762387195
1464 1464 g, t dbSNP:776802337
1478 1478 a, g, t dbSNP:368679125
1492 1492 c, g dbSNP:781260236
1496 1496 a, g dbSNP:764817410
1501 1501 a, g dbSNP:761286423
1505 1505 a, g dbSNP:777190282
1518 1518 c, t dbSNP:149695930
1520 1520 a, g dbSNP:140773512
1537 1537 c, t dbSNP:146438837
1540 1540 c, t dbSNP:143976596
1549 1549 a, t dbSNP:374559250
1553 1553 a, t dbSNP:746103110
1569 1569 a, g dbSNP:778796466
1573 1573 a, g dbSNP:372644335
1589 1589 a, g dbSNP:140198444
1602 1602 g, t dbSNP:781087988
1630 1630 a, t dbSNP:754933644
1640 1640 a, g dbSNP:746768201
1641 1641 g, t dbSNP:199510538
1656 1656 c, t dbSNP:775926751
1696 1696 a, g dbSNP:768004295
1699 1699 a, t dbSNP:373632536
1717 1717 c, g dbSNP:370248837
1728 1728 g, t dbSNP:758665871
1729 1729 a, g dbSNP:749342600
1753 1753 c, t dbSNP:773313492
1757 1757 c, t dbSNP:752804063
1758 1758 a, g dbSNP:746962101
1761 1761 a, g dbSNP:780024809
1765 1765 g, t dbSNP:144205393
1781 1781 c, t dbSNP:745690135
1783 1783 a, g dbSNP:778604488
1784 1784 c, g dbSNP:756880603
1785 1785 a, t dbSNP:753355273
1787 1787 c, t dbSNP:763699754
1793 1793 a, c dbSNP:756628396
1805 1805 c, t dbSNP:146157131
1806 1806 a, g dbSNP:767952529
1830 1830 a, g dbSNP:759926657
1835 1835 g, t dbSNP:375901101
1848 1848 a, g dbSNP:766587734
1849 1849 c, t dbSNP:763091316
1866 1866 g, t dbSNP:773221142
1867 1867 a, c, t dbSNP:200303151
1873 1873 c, g dbSNP:775375428
1883 1883 c, t dbSNP:771950360
1892 1892 c, t dbSNP:754392611
1901 1901 c, t dbSNP:772448306
1902 1902 a, g dbSNP:745472535
1903 1903 a, c dbSNP:770548473
1906 1906 c, g dbSNP:748958265
1916 1916 c, t dbSNP:142959373
1933 1933 a, g dbSNP:756702783
1935 1935 c, t dbSNP:752308935
1958 1958 c, g dbSNP:781690574
1964 1964 a, g dbSNP:148560784
1981 1981 a, g dbSNP:751885600
1985 1985 a, g dbSNP:144764663
1988 1988 a, g dbSNP:763366953
1993 1993 c, g dbSNP:750639868
2041 2041 g, t dbSNP:149387792
2047 2047 c, t dbSNP:200948146
2059 2059 a, g dbSNP:776713934
2062 2062 a, g dbSNP:772005838
2071 2071 a, g dbSNP:370765798
2077 2077 c, t dbSNP:772271125
2106 2106 a, g dbSNP:751996827
2134 2134 a, g dbSNP:184796918
2142 2142 c, t dbSNP:192743430
2143 2143 a, g dbSNP:145110602
2147 2147 a, g dbSNP:745346114
2162 2162 c, t dbSNP:377268147
2173 2173 c, t dbSNP:753885194
2200 2200 a, g dbSNP:764091042
2218 2218 a, g dbSNP:760863919
2219 2219 c, t dbSNP:187737855
2231 2231 a, g dbSNP:771044033
2237 2237 c, t dbSNP:147255018
2238 2238 a, g dbSNP:540569670
2240 2240 a, g dbSNP:773176825
2247 2247 a, c dbSNP:769508299
2249 2249 a, g dbSNP:746890051
2273 2273 a, c dbSNP:776403333
2277 2277 a, g dbSNP:768048579
2293 2293 a, t dbSNP:373141774
2298 2298 a, t dbSNP:143850231
2302 2302 a, t dbSNP:746571415
2304 2304 c, g dbSNP:138268044
2306 2306 a, g dbSNP:758926056
2318 2318 a, g dbSNP:371428199
2320 2320 a, g dbSNP:765112491
2323 2323 a, g dbSNP:777566944
2334 2334 a, g dbSNP:776118523
2342 2342 a, g dbSNP:768405501
2365 2365 a, g dbSNP:746453967
2369 2369 a, t dbSNP:771958941
2375 2375 c, g, t dbSNP:747865842
2376 2376 a, c dbSNP:201070097
2385 2385 c, t dbSNP:779449906
2391 2391 a, g dbSNP:757610874
2399 2399 a, g dbSNP:749699443
2412 2412 a, g dbSNP:777812135
2414 2414 a, t dbSNP:756392097
2423 2423 c, t dbSNP:752657026
2440 2440 a, g dbSNP:767721906
2450 2450 a, t dbSNP:755167575
2458 2458 a, g dbSNP:750381270
2469 2469 g, t dbSNP:765307016
2474 2474 c, t dbSNP:761492600
2476 2476 a, c dbSNP:776505971
2486 2486 a, g dbSNP:150377883
2488 2488 -, a dbSNP:35806617
2489 2489 a, g dbSNP:140363445
2525 2525 a, g dbSNP:377742035
2538 2538 a, c, t dbSNP:778731279
2541 2541 c, t dbSNP:190579053
2542 2542 a, g dbSNP:368933083
2544 2544 -, ggctgc dbSNP:749454699
2544 2544 a, g dbSNP:746293753
2549 2549 c, g dbSNP:749578530
2558 2558 a, g dbSNP:148257882
2582 2582 a, g dbSNP:780116069
2586 2586 a, g dbSNP:748392793
2588 2588 a, g dbSNP:200325876
2599 2599 a, g dbSNP:143131218
2614 2614 a, t dbSNP:755077854
2624 2624 c, t dbSNP:201436396
2625 2625 a, g dbSNP:778946615
2632 2632 a, g dbSNP:373465821
2643 2643 a, t dbSNP:757248077
2651 2651 a, g dbSNP:753509167
2662 2662 a, g dbSNP:763963394
2664 2664 c, t dbSNP:760440816
2667 2667 a, g dbSNP:752337343
2668 2668 a, g dbSNP:767194178
2700 2700 c, t dbSNP:759020755
2701 2701 a, g dbSNP:770685871
2710 2710 a, g dbSNP:773885877
2722 2722 c, t dbSNP:771278010
2728 2728 c, t dbSNP:763533295
2730 2730 -, ataatt dbSNP:745355429
2730 2730 a, g dbSNP:773654012
2741 2741 c, g, t dbSNP:2375726
2760 2760 c, t dbSNP:187611308
2766 2766 c, t dbSNP:769023794
2793 2793 g, t dbSNP:143434225
2798 2798 a, g dbSNP:755704953
2806 2806 c, t dbSNP:757677526
2825 2825 c, t dbSNP:147973478
2851 2851 a, g dbSNP:781315536
2856 2856 g, t dbSNP:764467478
2874 2874 c, t dbSNP:551846282

Target ORF information:

RefSeq Version NM_152633
Organism Homo sapiens (human)
Definition Homo sapiens Fanconi anemia, complementation group B (FANCB), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_152633

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
ATGACTAGCA AACAAGCAAT GTCATCTAAC GAACAAGAAA GGCTCTTGTG TTATAATGGG 
GAAGTCCTTG TTTTCCAGTT GTCTAAAGGA AATTTTGCAG ATAAAGAGCC TACAAAAACA
CCCATATTAC ATGTCAGAAG AATGGTATTT GACAGAGGAA CAAAAGTATT TGTTCAGAAG
TCCACTGGAT TTTTTACCAT AAAGGAAGAA AACTCTCATT TAAAAATCAT GTGTTGCAAC
TGTGTGTCAG ATTTCAGAAC TGGAATTAAC CTCCCTTACA TTGTGATAGA AAAAAATAAA
AAGAATAATG TTTTTGAATA TTTTTTACTA ATCCTTCACA GTACTAATAA ATTTGAAATG
CGTTTGAGTT TTAAACTAGG CTATGAGATG AAGGATGGCC TAAGGGTCCT TAATGGCCCT
TTAATTTTAT GGAGGCATGT CAAAGCATTC TTCTTTATCT CTTCTCAAAC TGGCAAAGTT
GTTAGTGTGT CAGGTAACTT TTCCTCTATT CAGTGGGCAG GGGAGATTGA AAATTTAGGT
ATGGTTTTAT TGGGACTAAA GGAATGTTGT TTATCTGAGG AAGAATGTAC TCAAGAGCCT
TCAAAATCAG ATTATGCAAT TTGGAATACC AAATTTTGTG TATATTCTCT TGAAAGTCAA
GAAGTATTAA GTGATATATA CATTATTCCT CCTGCTTACA GCAGTGTGGT GACTTATGTA
CATATTTGTG CAACTGAGAT CATCAAAAAC CAGTTAAGAA TATCTCTCAT TGCCCTTACT
CGAAAGAATC AGCTGATTTC ATTTCAGAAT GGAACTCCTA AAAATGTGTG CCAGCTTCCA
TTTGGAGATC CTTGTGCAGT TCAACTTATG GATTCAGGTG GAGGAAACCT CTTTTTCGTT
GTATCCTTTA TATCCAATAA TGCTTGTGCT GTATGGAAAG AGAGCTTTCA GGTTGCTGCT
AAATGGGAAA AACTTAGCTT AGTACTGATA GATGACTTTA TTGGAAGTGG AACTGAACAA
GTACTCCTAC TTTTTAAGGA CTCCTTGAAC TCAGACTGCC TGACTTCATT TAAAATAACG
GATCTTGGAA AAATAAACTA TTCGAGTGAA CCATCAGATT GCAATGAAGA TGACTTATTT
GAAGACAAAC AAGAGAATCG TTACCTGGTG GTTCCACCTC TAGAAACAGG ACTGAAAGTT
TGTTTTTCTT CTTTTCGGGA ATTACGGCAG CATCTGTTGC TTAAGGAAAA AATTATTTCA
AAATCTTACA AAGCTTTAAT AAACCTAGTT CAAGGAAAAG ATGATAATAC GTCAAGTGCA
GAGGAGAAGG AATGTCTTGT TCCTCTTTGT GGTGAAGAAG AAAATTCTGT CCATATCTTA
GATGAAAAGT TATCAGACAA TTTTCAAGAT TCAGAACAGC TAGTAGAGAA GATATGGTAT
CGTGTAATAG ATGATAGCTT GGTTGTTGGA GTGAAAACTA CATCTTCTTT GAAGCTGTCC
CTGAATGATG TGACTTTATC ATTGTTAATG GATCAAGCCC ATGACTCCAG ATTTCGGCTT
CTAAAGTGTC AAAATAGGGT GATTAAGTTG AGTACAAATC CTTTCCCAGC ACCATACTTG
ATGCCATGTG AAATAGGATT GGAAGCAAAA AGGGTCACGT TGACCCCTGA TAGCAAGAAA
GAGGAAAGCT TTGTTTGTGA ACACCCATCT AAGAAAGAGT GTGTACAGAT AATTACTGCT
GTAACATCTC TTTCACCACT TTTAACATTC AGTAAATTTT GTTGCACTGT ACTGCTACAA
ATTATGGAGA GAGAAAGTGG TAACTGTCCT AAAGATCGTT ATGTTGTGTG TGGCAGAGTT
TTTTTAAGTC TAGAAGATCT TTCAACTGGG AAGTACCTAC TGACATTTCC AAAGAAGAAA
CCTATAGAGC ACATGGAAGA TCTTTTTGCA CTTCTTGCAG CATTCCATAA ATCTTGTTTT
CAAATCACAT CACCCGGCTA TGCCCTGAAT TCAATGAAGG TGTGGCTCTT AGAACATATG
AAATGTGAAA TAATCAAAGA ATTTCCAGAA GTGTACTTTT GTGAAAGACC GGGAAGTTTC
TATGGGACAC TCTTCACTTG GAAACAGAGA ACACCATTCG AAGGGATTTT AATAATCTAT
TCCAGGAATC AAACAGTTAT GTTCCAGTGC CTTCATAATC TCATCAGAAT TCTCCCTATA
AACTGTTTCC TCAAAAATCT AAAATCAGGA AGTGAGAATT TCCTAATTGA TAATATGGCA
TTTACTTTGG AGAAGGAACT AGTCACCCTT AGTTCTCTTT CTTCTGCCAT AGCTAAACAT
GAAAGCAATT TTATGCAGAG GTGTGAAGTG AGCAAAGGAA AGAGTAGTGT CGTCGCGGCT
GCTTTATCAG ACAGAAGGGA AAATATCCAT CCCTACAGAA AAGAACTTCA GAGAGAAAAG
AAGAAAATGT TGCAAACGAA CCTAAAAGTG AGTGGTGCCC TTTACAGAGA AATAACTTTG
AAAGTAGCTG AGGTTCAGTT GAAATCAGAC TTTGCTGCAC AGAAACTGAG TAATTTATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25772
Accession Version NM_001018113.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2580bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product Fanconi anemia group B protein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP236844.1 and AK091383.1. This sequence is a reference standard in the RefSeqGene project. Summary: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Sequence Note: An upstream start codon is used for this RefSeq based on conservation in at least 10 vertebrate species including human, chimp, rhesus, treeshrew, guinea pig, rabbit, hedgehog, dog, horse and armadillo. In the literature (PubMed ID: 15502827), a start codon that is 6 aa downstream has been used as the translation AUG start codon based on conservation with mouse and chicken. No experimental evidence exists regarding which site is preferentially used. Also, no predicted N-terminal domains or signal peptides for either the longer or shorter proteins exist. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC136558.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
ATGACTAGCA AACAAGCAAT GTCATCTAAC GAACAAGAAA GGCTCTTGTG TTATAATGGG 
GAAGTCCTTG TTTTCCAGTT GTCTAAAGGA AATTTTGCAG ATAAAGAGCC TACAAAAACA
CCCATATTAC ATGTCAGAAG AATGGTATTT GACAGAGGAA CAAAAGTATT TGTTCAGAAG
TCCACTGGAT TTTTTACCAT AAAGGAAGAA AACTCTCATT TAAAAATCAT GTGTTGCAAC
TGTGTGTCAG ATTTCAGAAC TGGAATTAAC CTCCCTTACA TTGTGATAGA AAAAAATAAA
AAGAATAATG TTTTTGAATA TTTTTTACTA ATCCTTCACA GTACTAATAA ATTTGAAATG
CGTTTGAGTT TTAAACTAGG CTATGAGATG AAGGATGGCC TAAGGGTCCT TAATGGCCCT
TTAATTTTAT GGAGGCATGT CAAAGCATTC TTCTTTATCT CTTCTCAAAC TGGCAAAGTT
GTTAGTGTGT CAGGTAACTT TTCCTCTATT CAGTGGGCAG GGGAGATTGA AAATTTAGGT
ATGGTTTTAT TGGGACTAAA GGAATGTTGT TTATCTGAGG AAGAATGTAC TCAAGAGCCT
TCAAAATCAG ATTATGCAAT TTGGAATACC AAATTTTGTG TATATTCTCT TGAAAGTCAA
GAAGTATTAA GTGATATATA CATTATTCCT CCTGCTTACA GCAGTGTGGT GACTTATGTA
CATATTTGTG CAACTGAGAT CATCAAAAAC CAGTTAAGAA TATCTCTCAT TGCCCTTACT
CGAAAGAATC AGCTGATTTC ATTTCAGAAT GGAACTCCTA AAAATGTGTG CCAGCTTCCA
TTTGGAGATC CTTGTGCAGT TCAACTTATG GATTCAGGTG GAGGAAACCT CTTTTTCGTT
GTATCCTTTA TATCCAATAA TGCTTGTGCT GTATGGAAAG AGAGCTTTCA GGTTGCTGCT
AAATGGGAAA AACTTAGCTT AGTACTGATA GATGACTTTA TTGGAAGTGG AACTGAACAA
GTACTCCTAC TTTTTAAGGA CTCCTTGAAC TCAGACTGCC TGACTTCATT TAAAATAACG
GATCTTGGAA AAATAAACTA TTCGAGTGAA CCATCAGATT GCAATGAAGA TGACTTATTT
GAAGACAAAC AAGAGAATCG TTACCTGGTG GTTCCACCTC TAGAAACAGG ACTGAAAGTT
TGTTTTTCTT CTTTTCGGGA ATTACGGCAG CATCTGTTGC TTAAGGAAAA AATTATTTCA
AAATCTTACA AAGCTTTAAT AAACCTAGTT CAAGGAAAAG ATGATAATAC GTCAAGTGCA
GAGGAGAAGG AATGTCTTGT TCCTCTTTGT GGTGAAGAAG AAAATTCTGT CCATATCTTA
GATGAAAAGT TATCAGACAA TTTTCAAGAT TCAGAACAGC TAGTAGAGAA GATATGGTAT
CGTGTAATAG ATGATAGCTT GGTTGTTGGA GTGAAAACTA CATCTTCTTT GAAGCTGTCC
CTGAATGATG TGACTTTATC ATTGTTAATG GATCAAGCCC ATGACTCCAG ATTTCGGCTT
CTAAAGTGTC AAAATAGGGT GATTAAGTTG AGTACAAATC CTTTCCCAGC ACCATACTTG
ATGCCATGTG AAATAGGATT GGAAGCAAAA AGGGTCACGT TGACCCCTGA TAGCAAGAAA
GAGGAAAGCT TTGTTTGTGA ACACCCATCT AAGAAAGAGT GTGTACAGAT AATTACTGCT
GTAACATCTC TTTCACCACT TTTAACATTC AGTAAATTTT GTTGCACTGT ACTGCTACAA
ATTATGGAGA GAGAAAGTGG TAACTGTCCT AAAGATCGTT ATGTTGTGTG TGGCAGAGTT
TTTTTAAGTC TAGAAGATCT TTCAACTGGG AAGTACCTAC TGACATTTCC AAAGAAGAAA
CCTATAGAGC ACATGGAAGA TCTTTTTGCA CTTCTTGCAG CATTCCATAA ATCTTGTTTT
CAAATCACAT CACCCGGCTA TGCCCTGAAT TCAATGAAGG TGTGGCTCTT AGAACATATG
AAATGTGAAA TAATCAAAGA ATTTCCAGAA GTGTACTTTT GTGAAAGACC GGGAAGTTTC
TATGGGACAC TCTTCACTTG GAAACAGAGA ACACCATTCG AAGGGATTTT AATAATCTAT
TCCAGGAATC AAACAGTTAT GTTCCAGTGC CTTCATAATC TCATCAGAAT TCTCCCTATA
AACTGTTTCC TCAAAAATCT AAAATCAGGA AGTGAGAATT TCCTAATTGA TAATATGGCA
TTTACTTTGG AGAAGGAACT AGTCACCCTT AGTTCTCTTT CTTCTGCCAT AGCTAAACAT
GAAAGCAATT TTATGCAGAG GTGTGAAGTG AGCAAAGGAA AGAGTAGTGT CGTCGCGGCT
GCTTTATCAG ACAGAAGGGA AAATATCCAT CCCTACAGAA AAGAACTTCA GAGAGAAAAG
AAGAAAATGT TGCAAACGAA CCTAAAAGTG AGTGGTGCCC TTTACAGAGA AATAACTTTG
AAAGTAGCTG AGGTTCAGTT GAAATCAGAC TTTGCTGCAC AGAAACTGAG TAATTTATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001018123.1
CDS269..2848
Misc Feature(1)257..259(+)
Misc Feature(2)272..274(+)
Misc Feature(3)287..289(+)
Exon (1)1..77
Gene:FANCB
Gene Synonym:
Exon (2)78..198
Gene:FANCB
Gene Synonym:
Exon (3)199..1219
Gene:FANCB
Gene Synonym:
Exon (4)1220..1372
Gene:FANCB
Gene Synonym:
Exon (5)1373..1465
Gene:FANCB
Gene Synonym:
Exon (6)1466..1594
Gene:FANCB
Gene Synonym:
Exon (7)1595..1764
Gene:FANCB
Gene Synonym:
Exon (8)1765..2195
Gene:FANCB
Gene Synonym:
Exon (9)2196..2433
Gene:FANCB
Gene Synonym:
Exon (10)2434..3008
Gene:FANCB
Gene Synonym:
Translation
Position Chain Variation Link
37 37 a, g dbSNP:756766337
40 40 g, t dbSNP:149617434
50 50 c, g dbSNP:373175926
96 96 c, g dbSNP:2188383
100 100 g, t dbSNP:749253187
122 122 c, t dbSNP:779976534
142 142 c, t dbSNP:755929895
158 158 a, g, t dbSNP:185118376
190 190 a, g dbSNP:180836371
209 209 a, g dbSNP:766037619
219 219 a, g dbSNP:113427280
235 235 a, c dbSNP:746305258
242 242 a, g dbSNP:779269252
248 248 a, g dbSNP:771221018
255 255 c, t dbSNP:749284903
263 263 a, t dbSNP:777928160
264 264 a, g dbSNP:754812432
275 275 a, g dbSNP:139111718
276 276 g, t dbSNP:751501999
284 284 c, t dbSNP:5935815
285 285 a, c dbSNP:780032769
290 290 c, t dbSNP:758176689
298 298 a, c, g dbSNP:750078094
299 299 a, g dbSNP:370199124
309 309 a, g dbSNP:753239814
312 312 c, t dbSNP:368686910
322 322 c, t dbSNP:763676399
335 335 c, g dbSNP:761024549
337 337 c, t dbSNP:151173533
343 343 a, c dbSNP:772767612
361 361 c, t dbSNP:759943598
365 365 g, t dbSNP:774883903
395 395 a, t dbSNP:771007866
406 406 a, g dbSNP:749536805
421 421 c, t dbSNP:777646355
422 422 a, g dbSNP:769911209
430 430 a, g dbSNP:748284861
431 431 a, g dbSNP:779944907
462 462 a, t dbSNP:758372962
465 465 c, t dbSNP:750180189
467 467 a, g dbSNP:761346761
492 492 a, c dbSNP:756804647
498 498 c, t dbSNP:753536320
504 504 c, g dbSNP:763724576
530 530 a, g dbSNP:142101123
539 539 c, g dbSNP:752308987
541 541 c, t dbSNP:768094187
558 558 a, g dbSNP:760139481
575 575 a, g dbSNP:776604406
598 598 a, c dbSNP:201633684
629 629 c, t dbSNP:145928137
630 630 a, g dbSNP:142289802
636 636 g, t dbSNP:773468741
649 649 c, t dbSNP:769958914
655 655 c, g dbSNP:748195117
656 656 a, g dbSNP:776724055
658 658 a, g dbSNP:771949781
670 670 a, g dbSNP:147260208
682 682 a, t dbSNP:201281219
708 708 c, t dbSNP:757074045
726 726 a, t dbSNP:749099779
732 732 c, t dbSNP:777463253
733 733 c, t dbSNP:755858770
761 761 c, g dbSNP:146131050
772 772 c, g dbSNP:373738816
775 775 c, t dbSNP:149609970
776 776 a, c, g dbSNP:138251388
778 778 g, t dbSNP:775216604
781 781 a, g dbSNP:763353362
796 796 g, t dbSNP:773488727
812 812 g, t dbSNP:765459332
820 820 a, g dbSNP:771998496
822 822 g, t dbSNP:776636177
828 828 a, g dbSNP:768729913
852 852 a, g dbSNP:747162028
859 859 g, t dbSNP:774337829
863 863 a, g dbSNP:749426439
881 881 g, t dbSNP:749082728
883 883 c, t dbSNP:777464540
906 906 g, t dbSNP:755764501
920 920 c, g dbSNP:747819351
921 921 a, c dbSNP:781051710
922 922 a, c dbSNP:780311940
927 927 a, g dbSNP:751071983
934 934 a, g dbSNP:766888316
949 949 c, t dbSNP:370365613
956 956 c, t dbSNP:200970121
968 968 a, g dbSNP:750759993
970 970 c, t dbSNP:201709202
974 974 a, g dbSNP:746389250
979 979 a, g dbSNP:754044680
997 997 c, t dbSNP:186168143
1003 1003 c, t dbSNP:181962343
1009 1009 a, c dbSNP:760773732
1012 1012 a, c dbSNP:199762452
1021 1021 a, g dbSNP:775476952
1040 1040 g, t dbSNP:770865662
1056 1056 a, c dbSNP:762806947
1068 1068 c, t dbSNP:374217132
1069 1069 a, c dbSNP:773005941
1082 1082 a, g dbSNP:769701122
1089 1089 a, t dbSNP:748024447
1101 1101 a, g dbSNP:150435015
1108 1108 a, g dbSNP:112467543
1126 1126 a, g dbSNP:768472627
1132 1132 a, g dbSNP:746479455
1137 1137 c, t dbSNP:754552650
1157 1157 c, t dbSNP:758872342
1160 1160 c, t dbSNP:750905901
1165 1165 c, t dbSNP:753443421
1166 1166 a, g dbSNP:757610875
1178 1178 a, g dbSNP:754238911
1180 1180 a, g dbSNP:765890822
1184 1184 a, g dbSNP:764274377
1185 1185 a, g dbSNP:760825817
1197 1197 c, g dbSNP:752759773
1202 1202 c, t dbSNP:141443393
1207 1207 a, g dbSNP:767512088
1212 1212 c, g dbSNP:759722195
1228 1228 g, t dbSNP:139045247
1229 1229 a, g dbSNP:771467972
1257 1257 c, t dbSNP:200161949
1272 1272 a, g dbSNP:41309679
1317 1317 a, c dbSNP:757806819
1328 1328 c, g dbSNP:754149022
1335 1335 c, t dbSNP:142304943
1345 1345 a, t dbSNP:191379403
1347 1347 c, t dbSNP:138192474
1348 1348 a, c, g dbSNP:754983238
1366 1366 c, g dbSNP:369863081
1371 1371 c, t dbSNP:143585647
1372 1372 a, g dbSNP:761873562
1375 1375 g, t dbSNP:756433447
1381 1381 a, g dbSNP:748588943
1388 1388 c, t dbSNP:781251036
1399 1399 g, t dbSNP:148882589
1408 1408 a, t dbSNP:199909156
1416 1416 a, g dbSNP:376945933
1417 1417 a, g dbSNP:751649474
1427 1427 c, t dbSNP:145542355
1428 1428 a, g dbSNP:757202355
1445 1445 c, t dbSNP:753812355
1447 1447 c, t dbSNP:764156696
1476 1476 c, t dbSNP:747247621
1483 1483 a, g, t dbSNP:758546007
1493 1493 c, t dbSNP:750569208
1494 1494 a, g dbSNP:753030842
1502 1502 c, t dbSNP:765480337
1518 1518 a, c dbSNP:752391089
1524 1524 c, t dbSNP:759581894
1531 1531 a, g dbSNP:759388298
1535 1535 c, t dbSNP:776805534
1557 1557 c, t dbSNP:376384388
1576 1576 c, t dbSNP:762430531
1578 1578 c, t dbSNP:772802668
1579 1579 a, g, t dbSNP:762387195
1585 1585 g, t dbSNP:776802337
1599 1599 a, g, t dbSNP:368679125
1613 1613 c, g dbSNP:781260236
1617 1617 a, g dbSNP:764817410
1622 1622 a, g dbSNP:761286423
1626 1626 a, g dbSNP:777190282
1639 1639 c, t dbSNP:149695930
1641 1641 a, g dbSNP:140773512
1658 1658 c, t dbSNP:146438837
1661 1661 c, t dbSNP:143976596
1670 1670 a, t dbSNP:374559250
1674 1674 a, t dbSNP:746103110
1690 1690 a, g dbSNP:778796466
1694 1694 a, g dbSNP:372644335
1710 1710 a, g dbSNP:140198444
1723 1723 g, t dbSNP:781087988
1751 1751 a, t dbSNP:754933644
1761 1761 a, g dbSNP:746768201
1762 1762 g, t dbSNP:199510538
1777 1777 c, t dbSNP:775926751
1817 1817 a, g dbSNP:768004295
1820 1820 a, t dbSNP:373632536
1838 1838 c, g dbSNP:370248837
1849 1849 g, t dbSNP:758665871
1850 1850 a, g dbSNP:749342600
1874 1874 c, t dbSNP:773313492
1878 1878 c, t dbSNP:752804063
1879 1879 a, g dbSNP:746962101
1882 1882 a, g dbSNP:780024809
1886 1886 g, t dbSNP:144205393
1902 1902 c, t dbSNP:745690135
1904 1904 a, g dbSNP:778604488
1905 1905 c, g dbSNP:756880603
1906 1906 a, t dbSNP:753355273
1908 1908 c, t dbSNP:763699754
1914 1914 a, c dbSNP:756628396
1926 1926 c, t dbSNP:146157131
1927 1927 a, g dbSNP:767952529
1951 1951 a, g dbSNP:759926657
1956 1956 g, t dbSNP:375901101
1969 1969 a, g dbSNP:766587734
1970 1970 c, t dbSNP:763091316
1987 1987 g, t dbSNP:773221142
1988 1988 a, c, t dbSNP:200303151
1994 1994 c, g dbSNP:775375428
2004 2004 c, t dbSNP:771950360
2013 2013 c, t dbSNP:754392611
2022 2022 c, t dbSNP:772448306
2023 2023 a, g dbSNP:745472535
2024 2024 a, c dbSNP:770548473
2027 2027 c, g dbSNP:748958265
2037 2037 c, t dbSNP:142959373
2054 2054 a, g dbSNP:756702783
2056 2056 c, t dbSNP:752308935
2079 2079 c, g dbSNP:781690574
2085 2085 a, g dbSNP:148560784
2102 2102 a, g dbSNP:751885600
2106 2106 a, g dbSNP:144764663
2109 2109 a, g dbSNP:763366953
2114 2114 c, g dbSNP:750639868
2162 2162 g, t dbSNP:149387792
2168 2168 c, t dbSNP:200948146
2180 2180 a, g dbSNP:776713934
2183 2183 a, g dbSNP:772005838
2192 2192 a, g dbSNP:370765798
2198 2198 c, t dbSNP:772271125
2227 2227 a, g dbSNP:751996827
2255 2255 a, g dbSNP:184796918
2263 2263 c, t dbSNP:192743430
2264 2264 a, g dbSNP:145110602
2268 2268 a, g dbSNP:745346114
2283 2283 c, t dbSNP:377268147
2294 2294 c, t dbSNP:753885194
2321 2321 a, g dbSNP:764091042
2339 2339 a, g dbSNP:760863919
2340 2340 c, t dbSNP:187737855
2352 2352 a, g dbSNP:771044033
2358 2358 c, t dbSNP:147255018
2359 2359 a, g dbSNP:540569670
2361 2361 a, g dbSNP:773176825
2368 2368 a, c dbSNP:769508299
2370 2370 a, g dbSNP:746890051
2394 2394 a, c dbSNP:776403333
2398 2398 a, g dbSNP:768048579
2414 2414 a, t dbSNP:373141774
2419 2419 a, t dbSNP:143850231
2423 2423 a, t dbSNP:746571415
2425 2425 c, g dbSNP:138268044
2427 2427 a, g dbSNP:758926056
2439 2439 a, g dbSNP:371428199
2441 2441 a, g dbSNP:765112491
2444 2444 a, g dbSNP:777566944
2455 2455 a, g dbSNP:776118523
2463 2463 a, g dbSNP:768405501
2486 2486 a, g dbSNP:746453967
2490 2490 a, t dbSNP:771958941
2496 2496 c, g, t dbSNP:747865842
2497 2497 a, c dbSNP:201070097
2506 2506 c, t dbSNP:779449906
2512 2512 a, g dbSNP:757610874
2520 2520 a, g dbSNP:749699443
2533 2533 a, g dbSNP:777812135
2535 2535 a, t dbSNP:756392097
2544 2544 c, t dbSNP:752657026
2561 2561 a, g dbSNP:767721906
2571 2571 a, t dbSNP:755167575
2579 2579 a, g dbSNP:750381270
2590 2590 g, t dbSNP:765307016
2595 2595 c, t dbSNP:761492600
2597 2597 a, c dbSNP:776505971
2607 2607 a, g dbSNP:150377883
2609 2609 -, a dbSNP:35806617
2610 2610 a, g dbSNP:140363445
2646 2646 a, g dbSNP:377742035
2659 2659 a, c, t dbSNP:778731279
2662 2662 c, t dbSNP:190579053
2663 2663 a, g dbSNP:368933083
2665 2665 -, ggctgc dbSNP:749454699
2665 2665 a, g dbSNP:746293753
2670 2670 c, g dbSNP:749578530
2679 2679 a, g dbSNP:148257882
2703 2703 a, g dbSNP:780116069
2707 2707 a, g dbSNP:748392793
2709 2709 a, g dbSNP:200325876
2720 2720 a, g dbSNP:143131218
2735 2735 a, t dbSNP:755077854
2745 2745 c, t dbSNP:201436396
2746 2746 a, g dbSNP:778946615
2753 2753 a, g dbSNP:373465821
2764 2764 a, t dbSNP:757248077
2772 2772 a, g dbSNP:753509167
2783 2783 a, g dbSNP:763963394
2785 2785 c, t dbSNP:760440816
2788 2788 a, g dbSNP:752337343
2789 2789 a, g dbSNP:767194178
2821 2821 c, t dbSNP:759020755
2822 2822 a, g dbSNP:770685871
2831 2831 a, g dbSNP:773885877
2843 2843 c, t dbSNP:771278010
2849 2849 c, t dbSNP:763533295
2851 2851 -, ataatt dbSNP:745355429
2851 2851 a, g dbSNP:773654012
2862 2862 c, g, t dbSNP:2375726
2881 2881 c, t dbSNP:187611308
2887 2887 c, t dbSNP:769023794
2914 2914 g, t dbSNP:143434225
2919 2919 a, g dbSNP:755704953
2927 2927 c, t dbSNP:757677526
2946 2946 c, t dbSNP:147973478
2972 2972 a, g dbSNP:781315536
2977 2977 g, t dbSNP:764467478
2995 2995 c, t dbSNP:551846282

Target ORF information:

RefSeq Version NM_001018113
Organism Homo sapiens (human)
Definition Homo sapiens Fanconi anemia, complementation group B (FANCB), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001018113

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
ATGACTAGCA AACAAGCAAT GTCATCTAAC GAACAAGAAA GGCTCTTGTG TTATAATGGG 
GAAGTCCTTG TTTTCCAGTT GTCTAAAGGA AATTTTGCAG ATAAAGAGCC TACAAAAACA
CCCATATTAC ATGTCAGAAG AATGGTATTT GACAGAGGAA CAAAAGTATT TGTTCAGAAG
TCCACTGGAT TTTTTACCAT AAAGGAAGAA AACTCTCATT TAAAAATCAT GTGTTGCAAC
TGTGTGTCAG ATTTCAGAAC TGGAATTAAC CTCCCTTACA TTGTGATAGA AAAAAATAAA
AAGAATAATG TTTTTGAATA TTTTTTACTA ATCCTTCACA GTACTAATAA ATTTGAAATG
CGTTTGAGTT TTAAACTAGG CTATGAGATG AAGGATGGCC TAAGGGTCCT TAATGGCCCT
TTAATTTTAT GGAGGCATGT CAAAGCATTC TTCTTTATCT CTTCTCAAAC TGGCAAAGTT
GTTAGTGTGT CAGGTAACTT TTCCTCTATT CAGTGGGCAG GGGAGATTGA AAATTTAGGT
ATGGTTTTAT TGGGACTAAA GGAATGTTGT TTATCTGAGG AAGAATGTAC TCAAGAGCCT
TCAAAATCAG ATTATGCAAT TTGGAATACC AAATTTTGTG TATATTCTCT TGAAAGTCAA
GAAGTATTAA GTGATATATA CATTATTCCT CCTGCTTACA GCAGTGTGGT GACTTATGTA
CATATTTGTG CAACTGAGAT CATCAAAAAC CAGTTAAGAA TATCTCTCAT TGCCCTTACT
CGAAAGAATC AGCTGATTTC ATTTCAGAAT GGAACTCCTA AAAATGTGTG CCAGCTTCCA
TTTGGAGATC CTTGTGCAGT TCAACTTATG GATTCAGGTG GAGGAAACCT CTTTTTCGTT
GTATCCTTTA TATCCAATAA TGCTTGTGCT GTATGGAAAG AGAGCTTTCA GGTTGCTGCT
AAATGGGAAA AACTTAGCTT AGTACTGATA GATGACTTTA TTGGAAGTGG AACTGAACAA
GTACTCCTAC TTTTTAAGGA CTCCTTGAAC TCAGACTGCC TGACTTCATT TAAAATAACG
GATCTTGGAA AAATAAACTA TTCGAGTGAA CCATCAGATT GCAATGAAGA TGACTTATTT
GAAGACAAAC AAGAGAATCG TTACCTGGTG GTTCCACCTC TAGAAACAGG ACTGAAAGTT
TGTTTTTCTT CTTTTCGGGA ATTACGGCAG CATCTGTTGC TTAAGGAAAA AATTATTTCA
AAATCTTACA AAGCTTTAAT AAACCTAGTT CAAGGAAAAG ATGATAATAC GTCAAGTGCA
GAGGAGAAGG AATGTCTTGT TCCTCTTTGT GGTGAAGAAG AAAATTCTGT CCATATCTTA
GATGAAAAGT TATCAGACAA TTTTCAAGAT TCAGAACAGC TAGTAGAGAA GATATGGTAT
CGTGTAATAG ATGATAGCTT GGTTGTTGGA GTGAAAACTA CATCTTCTTT GAAGCTGTCC
CTGAATGATG TGACTTTATC ATTGTTAATG GATCAAGCCC ATGACTCCAG ATTTCGGCTT
CTAAAGTGTC AAAATAGGGT GATTAAGTTG AGTACAAATC CTTTCCCAGC ACCATACTTG
ATGCCATGTG AAATAGGATT GGAAGCAAAA AGGGTCACGT TGACCCCTGA TAGCAAGAAA
GAGGAAAGCT TTGTTTGTGA ACACCCATCT AAGAAAGAGT GTGTACAGAT AATTACTGCT
GTAACATCTC TTTCACCACT TTTAACATTC AGTAAATTTT GTTGCACTGT ACTGCTACAA
ATTATGGAGA GAGAAAGTGG TAACTGTCCT AAAGATCGTT ATGTTGTGTG TGGCAGAGTT
TTTTTAAGTC TAGAAGATCT TTCAACTGGG AAGTACCTAC TGACATTTCC AAAGAAGAAA
CCTATAGAGC ACATGGAAGA TCTTTTTGCA CTTCTTGCAG CATTCCATAA ATCTTGTTTT
CAAATCACAT CACCCGGCTA TGCCCTGAAT TCAATGAAGG TGTGGCTCTT AGAACATATG
AAATGTGAAA TAATCAAAGA ATTTCCAGAA GTGTACTTTT GTGAAAGACC GGGAAGTTTC
TATGGGACAC TCTTCACTTG GAAACAGAGA ACACCATTCG AAGGGATTTT AATAATCTAT
TCCAGGAATC AAACAGTTAT GTTCCAGTGC CTTCATAATC TCATCAGAAT TCTCCCTATA
AACTGTTTCC TCAAAAATCT AAAATCAGGA AGTGAGAATT TCCTAATTGA TAATATGGCA
TTTACTTTGG AGAAGGAACT AGTCACCCTT AGTTCTCTTT CTTCTGCCAT AGCTAAACAT
GAAAGCAATT TTATGCAGAG GTGTGAAGTG AGCAAAGGAA AGAGTAGTGT CGTCGCGGCT
GCTTTATCAG ACAGAAGGGA AAATATCCAT CCCTACAGAA AAGAACTTCA GAGAGAAAAG
AAGAAAATGT TGCAAACGAA CCTAAAAGTG AGTGGTGCCC TTTACAGAGA AATAACTTTG
AAAGTAGCTG AGGTTCAGTT GAAATCAGAC TTTGCTGCAC AGAAACTGAG TAATTTATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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