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FANCG cDNA ORF clone, Homo sapiens (human)

Gene Symbol FANCG
Entrez Gene ID 2189
Full Name Fanconi anemia, complementation group G
Synonyms FAG, XRCC9
General protein information
Preferred Names
Fanconi anemia group G protein
Names
Fanconi anemia group G protein
DNA repair protein XRCC9
X-ray repair, complementing defective, in Chinese hamster, 9
X-ray repair complementing defective repair in Chinese hamster cells 9
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9p13

Summary The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

602956

Disorder Html: Fanconi anemia, complementation group G (3)

mRNA and Protein(s)

mRNA Protein Name
NM_004629 NP_004620 Fanconi anemia group G protein



Homo sapiens (human) FANCG NP_004620.1
Pan troglodytes (chimpanzee) FANCG XP_001165190.1
Macaca mulatta (Rhesus monkey) FANCG XP_001092322.1
Canis lupus familiaris (dog) FANCG XP_854703.1
Bos taurus (cattle) FANCG NP_001095757.1
Mus musculus (house mouse) Fancg NP_444311.1
Rattus norvegicus (Norway rat) Fancg XP_006238187.1
Gallus gallus (chicken) FANCG NP_989709.1
Danio rerio (zebrafish) fancg NP_991202.1
Xenopus (Silurana) tropicalis (western clawed frog) fancg NP_001120193.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following FANCG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FANCG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu25922
NM_004629 Homo sapiens Fanconi anemia, complementation group G (FANCG), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
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30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu25922
Clone ID Related Accession (Same CDS sequence) NM_004629
Accession Version NM_004629.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1869bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product Fanconi anemia group G protein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ007669.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ007669.1, BC011623.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGTCCCGCC AGACCACCTC TGTGGGCTCC AGCTGCCTGG ACCTGTGGAG GGAAAAGAAT 
GACCGGCTCG TTCGACAGGC CAAGGTGGCT CAGAACTCCG GTCTGACTCT GAGGCGACAG
CAGTTGGCTC AGGATGCACT GGAAGGGCTC AGAGGGCTCC TCCATAGTCT GCAAGGGCTC
CCTGCAGCTG TTCCTGTTCT TCCCTTGGAG CTGACTGTCA CCTGCAACTT CATTATCCTG
AGGGCAAGCT TGGCCCAGGG TTTCACAGAG GATCAGGCCC AGGATATCCA GCGGAGCCTA
GAGAGAGTGC TGGAGACACA GGAGCAGCAG GGGCCCAGGT TGGAACAGGG GCTCAGGGAG
CTGTGGGACT CTGTCCTTCG TGCTTCCTGC CTTCTGCCGG AGCTGCTGTC TGCCCTGCAC
CGCCTGGTTG GCCTGCAGGC TGCCCTCTGG TTGAGTGCTG ACCGTCTTGG GGACCTGGCC
TTGTTACTAG AGACCCTGAA TGGCAGCCAG AGTGGAGCCT CTAAGGATCT GCTGTTACTT
CTGAAAACTT GGAGTCCCCC AGCTGAGGAA TTAGATGCTC CATTGACCCT GCAGGATGCC
CAGGGATTGA AGGATGTCCT CCTGACAGCA TTTGCCTACC GCCAAGGTCT CCAGGAGCTG
ATCACAGGGA ACCCAGACAA GGCACTAAGC AGCCTTCATG AAGCGGCCTC AGGCCTGTGT
CCACGGCCTG TGTTGGTCCA GGTGTACACA GCACTGGGGT CCTGTCACCG TAAGATGGGA
AATCCACAGA GAGCACTGTT GTACTTGGTT GCAGCCCTGA AAGAGGGATC AGCCTGGGGT
CCTCCACTTC TGGAGGCCTC TAGGCTCTAT CAGCAACTGG GGGACACAAC AGCAGAGCTG
GAGAGTCTGG AGCTGCTAGT TGAGGCCTTG AATGTCCCAT GCAGTTCCAA AGCCCCGCAG
TTTCTCATTG AGGTAGAATT ACTACTGCCA CCACCTGACC TAGCCTCACC CCTTCATTGT
GGCACTCAGA GCCAGACCAA GCACATACTA GCAAGCAGGT GCCTACAGAC GGGGAGGGCA
GGAGACGCTG CAGAGCATTA CTTGGACCTG CTGGCCCTGT TGCTGGATAG CTCGGAGCCA
AGGTTCTCCC CACCCCCCTC CCCTCCAGGG CCCTGTATGC CTGAGGTGTT TTTGGAGGCA
GCGGTAGCAC TGATCCAGGC AGGCAGAGCC CAAGATGCCT TGACTCTATG TGAGGAGTTG
CTCAGCCGCA CATCATCTCT GCTACCCAAG ATGTCCCGGC TGTGGGAAGA TGCCAGAAAA
GGAACCAAGG AACTGCCATA CTGCCCACTC TGGGTCTCTG CCACCCACCT GCTTCAGGGC
CAGGCCTGGG TTCAACTGGG TGCCCAAAAA GTGGCAATTA GTGAATTTAG CAGGTGCCTC
GAGCTGCTCT TCCGGGCCAC ACCTGAGGAA AAAGAACAAG GGGCAGCTTT CAACTGTGAG
CAGGGATGTA AGTCAGATGC GGCACTGCAG CAGCTTCGGG CAGCCGCCCT AATTAGTCGT
GGACTGGAAT GGGTAGCCAG CGGCCAGGAT ACCAAAGCCT TACAGGACTT CCTCCTCAGT
GTGCAGATGT GCCCAGGTAA TCGAGACACT TACTTTCACC TGCTTCAGAC TCTGAAGAGG
CTAGATCGGA GGGATGAGGC CACTGCACTC TGGTGGAGGC TGGAGGCCCA AACTAAGGGG
TCACATGAAG ATGCTCTGTG GTCTCTCCCC CTGTACCTAG AAAGCTATTT GAGCTGGATC
CGTCCCTCTG ATCGTGACGC CTTCCTTGAA GAATTTCGGA CATCTCTGCC AAAGTCTTGT
GACCTGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_004620.1
CDS493..2361
Misc Feature(1)454..456(+)
Misc Feature(2)511..513(+)
Misc Feature(3)1129..1368(+)
Misc Feature(4)1129..1203(+)
Misc Feature(5)1225..1317(+)
Misc Feature(6)1228..1329(+)
Misc Feature(7)1330..1377(+)
Misc Feature(8)1522..1623(+)
Misc Feature(9)1639..1641(+)
Misc Feature(10)1651..1653(+)
Misc Feature(11)1849..1950(+)
Misc Feature(12)2032..2133(+)
Exon (1)1..576
Gene:FANCG
Gene Synonym:
Exon (2)577..667
Gene:FANCG
Gene Synonym:
Exon (3)668..799
Gene:FANCG
Gene Synonym:
Exon (4)800..1002
Gene:FANCG
Gene Synonym:
Exon (5)1003..1138
Gene:FANCG
Gene Synonym:
Exon (6)1139..1269
Gene:FANCG
Gene Synonym:
Exon (7)1270..1416
Gene:FANCG
Gene Synonym:
Exon (8)1417..1568
Gene:FANCG
Gene Synonym:
Exon (9)1569..1635
Gene:FANCG
Gene Synonym:
Exon (10)1636..1925
Gene:FANCG
Gene Synonym:
Exon (11)1926..1972
Gene:FANCG
Gene Synonym:
Exon (12)1973..2128
Gene:FANCG
Gene Synonym:
Exon (13)2129..2252
Gene:FANCG
Gene Synonym:
Exon (14)2253..2631
Gene:FANCG
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_004629
Organism Homo sapiens (human)
Definition Homo sapiens Fanconi anemia, complementation group G (FANCG), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_004629

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGTCCCGCC AGACCACCTC TGTGGGCTCC AGCTGCCTGG ACCTGTGGAG GGAAAAGAAT 
GACCGGCTCG TTCGACAGGC CAAGGTGGCT CAGAACTCCG GTCTGACTCT GAGGCGACAG
CAGTTGGCTC AGGATGCACT GGAAGGGCTC AGAGGGCTCC TCCATAGTCT GCAAGGGCTC
CCTGCAGCTG TTCCTGTTCT TCCCTTGGAG CTGACTGTCA CCTGCAACTT CATTATCCTG
AGGGCAAGCT TGGCCCAGGG TTTCACAGAG GATCAGGCCC AGGATATCCA GCGGAGCCTA
GAGAGAGTGC TGGAGACACA GGAGCAGCAG GGGCCCAGGT TGGAACAGGG GCTCAGGGAG
CTGTGGGACT CTGTCCTTCG TGCTTCCTGC CTTCTGCCGG AGCTGCTGTC TGCCCTGCAC
CGCCTGGTTG GCCTGCAGGC TGCCCTCTGG TTGAGTGCTG ACCGTCTTGG GGACCTGGCC
TTGTTACTAG AGACCCTGAA TGGCAGCCAG AGTGGAGCCT CTAAGGATCT GCTGTTACTT
CTGAAAACTT GGAGTCCCCC AGCTGAGGAA TTAGATGCTC CATTGACCCT GCAGGATGCC
CAGGGATTGA AGGATGTCCT CCTGACAGCA TTTGCCTACC GCCAAGGTCT CCAGGAGCTG
ATCACAGGGA ACCCAGACAA GGCACTAAGC AGCCTTCATG AAGCGGCCTC AGGCCTGTGT
CCACGGCCTG TGTTGGTCCA GGTGTACACA GCACTGGGGT CCTGTCACCG TAAGATGGGA
AATCCACAGA GAGCACTGTT GTACTTGGTT GCAGCCCTGA AAGAGGGATC AGCCTGGGGT
CCTCCACTTC TGGAGGCCTC TAGGCTCTAT CAGCAACTGG GGGACACAAC AGCAGAGCTG
GAGAGTCTGG AGCTGCTAGT TGAGGCCTTG AATGTCCCAT GCAGTTCCAA AGCCCCGCAG
TTTCTCATTG AGGTAGAATT ACTACTGCCA CCACCTGACC TAGCCTCACC CCTTCATTGT
GGCACTCAGA GCCAGACCAA GCACATACTA GCAAGCAGGT GCCTACAGAC GGGGAGGGCA
GGAGACGCTG CAGAGCATTA CTTGGACCTG CTGGCCCTGT TGCTGGATAG CTCGGAGCCA
AGGTTCTCCC CACCCCCCTC CCCTCCAGGG CCCTGTATGC CTGAGGTGTT TTTGGAGGCA
GCGGTAGCAC TGATCCAGGC AGGCAGAGCC CAAGATGCCT TGACTCTATG TGAGGAGTTG
CTCAGCCGCA CATCATCTCT GCTACCCAAG ATGTCCCGGC TGTGGGAAGA TGCCAGAAAA
GGAACCAAGG AACTGCCATA CTGCCCACTC TGGGTCTCTG CCACCCACCT GCTTCAGGGC
CAGGCCTGGG TTCAACTGGG TGCCCAAAAA GTGGCAATTA GTGAATTTAG CAGGTGCCTC
GAGCTGCTCT TCCGGGCCAC ACCTGAGGAA AAAGAACAAG GGGCAGCTTT CAACTGTGAG
CAGGGATGTA AGTCAGATGC GGCACTGCAG CAGCTTCGGG CAGCCGCCCT AATTAGTCGT
GGACTGGAAT GGGTAGCCAG CGGCCAGGAT ACCAAAGCCT TACAGGACTT CCTCCTCAGT
GTGCAGATGT GCCCAGGTAA TCGAGACACT TACTTTCACC TGCTTCAGAC TCTGAAGAGG
CTAGATCGGA GGGATGAGGC CACTGCACTC TGGTGGAGGC TGGAGGCCCA AACTAAGGGG
TCACATGAAG ATGCTCTGTG GTCTCTCCCC CTGTACCTAG AAAGCTATTT GAGCTGGATC
CGTCCCTCTG ATCGTGACGC CTTCCTTGAA GAATTTCGGA CATCTCTGCC AAAGTCTTGT
GACCTGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Fanconi anaemia in black South African patients heterozygous for the FANCG c.637-643delTACCGCC founder mutation
S. Afr. Med. J. 103 (12 SUPPL 1), 970-973 (2013)
Wainstein T, Kerr R, Mitchell CL, Madaree S, Essop FB, Vorster E, Wainwright R, Poole J and Krause A.


book

FANCA and FANCG are the major Fanconi anemia genes in the Korean population
Clin. Genet. 84 (3), 271-275 (2013)
Park J, Chung NG, Chae H, Kim M, Lee S, Kim Y, Lee JW, Cho B, Jeong DC and Park IY.


book

Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG
Toxicol. Sci. 123 (2), 480-490 (2011)
Tsai YS, Lin CS, Chiang SL, Lee CH, Lee KW and Ko YC.


book

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study
Diabetes Care 33 (10), 2250-2253 (2010)
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC and Anand S.


book

Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex
Mol. Cell. Biol. 19 (7), 4866-4873 (1999)
Garcia-Higuera I, Kuang Y, Naf D, Wasik J and D'Andrea AD.


book

The Fanconi anaemia group G gene FANCG is identical with XRCC9
Nat. Genet. 20 (3), 281-283 (1998)
de Winter JP, Waisfisz Q, Rooimans MA, van Berkel CG, Bosnoyan-Collins L, Alon N, Carreau M, Bender O, Demuth I, Schindler D, Pronk JC, Arwert F, Hoehn H, Digweed M, Buchwald M and Joenje H.


book

Evidence for at least eight Fanconi anemia genes
Am. J. Hum. Genet. 61 (4), 940-944 (1997)
Joenje H, Oostra AB, Wijker M, di Summa FM, van Berkel CG, Rooimans MA, Ebell W, van Weel M, Pronk JC, Buchwald M and Arwert F.


book

The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells
Proc. Natl. Acad. Sci. U.S.A. 94 (17), 9232-9237 (1997)
Liu N, Lamerdin JE, Tucker JD, Zhou ZQ, Walter CA, Albala JS, Busch DB and Thompson LH.


book

Esophageal Atresia/Tracheoesophageal Fistula Overview
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Scott,D.A.


book

Fanconi Anemia
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Alter,B.P. and Kupfer,G.


 
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