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GSX1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol GSX1
Entrez Gene ID 219409
Full Name GS homeobox 1
Synonyms GSH1, Gsh-1
General protein information
Preferred Names
GS homeobox 1
Names
GS homeobox 1
GS homeo box protein 1
homeobox protein Gsh-1
genomic screened homeo box 1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

13

13q12.2

Summary lac of sum
Disorder MIM:

616542


mRNA and Protein(s)

mRNA Protein Name
NM_145657 NP_663632 GS homeobox 1


Homo sapiens (human) GSX1 NP_663632.1
Pan troglodytes (chimpanzee) GSX1 XP_522643.3
Macaca mulatta (Rhesus monkey) GSX1 XP_001096656.2
Canis lupus familiaris (dog) GSX1 XP_003639921.1
Bos taurus (cattle) GSX1 NP_001098918.1
Mus musculus (house mouse) Gsx1 NP_032204.1
Rattus norvegicus (Norway rat) Gsx1 NP_001178592.1
Danio rerio (zebrafish) gsx1 NP_001012251.1
Xenopus (Silurana) tropicalis (western clawed frog) gsx1 NP_001039254.1

Component

ID Name Evidence
GO:0005634 nucleus IEA

Function

ID Name Evidence
GO:0003700 sequence-specific DNA binding transcription factor activity IEA
GO:0043565 sequence-specific DNA binding IDA

Process

ID Name Evidence
GO:0006355 regulation of transcription, DNA-dependent IEA
GO:0007275 multicellular organismal development IEA
GO:0021527 spinal cord association neuron differentiation IEA
GO:0021854 hypothalamus development IEA
GO:0021984 adenohypophysis development IEA
GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA
GO:0048663 neuron fate commitment IEA

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GSX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GSX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu77884
NM_145657 Homo sapiens GS homeobox 1 (GSX1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
Starting from $99.50
$199.00

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu77884
Clone ID Related Accession (Same CDS sequence) NM_145657
Accession Version NM_145657.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 795bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 18-DEC-2014
Organism Homo sapiens (human)
Product GS homeobox 1
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB044157.1 and AL390738.4. On Dec 18, 2014 this sequence version replaced gi:33457325. ##Evidence-Data-START## Transcript exon combination :: AB044157.1 [ECO:0000332] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCCGCGCT CCTTCCTGGT GGACTCGCTA GTGCTGCGCG AGGCGGGCGA GAAGAAGGCG 
CCCGAGGGCA GCCCGCCGCC GCTCTTCCCC TACGCTGTGC CCCCGCCGCA CGCGCTGCAC
GGTCTCTCGC CTGGCGCCTG CCACGCGCGC AAGGCTGGGC TGCTGTGCGT GTGCCCGCTC
TGCGTCACCG CCTCGCAGCT GCATGGGCCC CCCGGGCCGC CCGCGCTGCC TCTACTCAAG
GCTTCCTTCC CACCCTTCGG CTCGCAGTAC TGCCACGCGC CCCTGGGCCG CCAGCACTCT
GCTGTGTCGC CCGGGGTCGC TCACGGCCCG GCCGCCGCTG CTGCTGCCGC CGCGCTCTAC
CAGACCTCCT ACCCGCTGCC TGACCCCAGG CAGTTCCACT GCATCTCTGT GGACAGCAGC
TCTAACCAGC TGCCCAGCAG CAAGAGGATG CGCACGGCTT TCACCAGCAC GCAGCTGCTA
GAGCTGGAGC GCGAGTTCGC TTCTAATATG TACCTGTCCC GCCTACGTCG CATCGAGATC
GCGACCTACC TGAATCTGTC CGAGAAGCAG GTGAAGATCT GGTTTCAGAA CCGCCGAGTG
AAGCACAAGA AGGAGGGCAA GGGCAGCAAC CATCGTGGCG GCGGCGGCGG GGGTGCCGGT
GGTGGCGGGA GCGCACCGCA AGGCTGCAAG TGCGCATCGC TCTCCTCAGC CAAGTGCTCC
GAGGATGACG ACGAATTGCC CATGTCTCCG TCCTCCTCAG GGAAGGACGA CCGGGATCTT
ACGGTCACTC CCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_663632.1
CDS49..843
Misc Feature(1)49..108(+)
Misc Feature(2)490..663(+)
Misc Feature(3)490..660(+)
Misc Feature(4)496..648(+)
Exon (1)1..460
Gene:GSX1
Gene Synonym:
Exon (2)461..847
Gene:GSX1
Gene Synonym:
Translation
Position Chain Variation Link
41 41 c, t dbSNP:562655839
43 43 a, g dbSNP:531800833
45 45 a, g dbSNP:573793551
57 57 c, t dbSNP:747576698
70 70 a, g dbSNP:752716631
83 83 c, t dbSNP:757690918
93 93 a, g dbSNP:551560936
98 98 -, aga dbSNP:756729588
108 108 g, t dbSNP:781634632
153 153 g, t dbSNP:746246077
155 155 c, t dbSNP:769856430
159 159 a, c dbSNP:775809436
162 162 a, g, t dbSNP:571843674
173 173 c, t dbSNP:773125002
196 196 a, c dbSNP:760676120
198 198 c, t dbSNP:534121459
213 213 a, g dbSNP:548155374
250 250 a, c dbSNP:745373226
256 256 c, t dbSNP:567910687
261 261 c, t dbSNP:766312266
270 270 a, c dbSNP:776354379
272 272 a, c dbSNP:759399712
273 273 a, g dbSNP:764757658
274 274 a, c dbSNP:752434816
275 275 -, g dbSNP:747020900
276 276 g, t dbSNP:757832673
277 277 a, c dbSNP:763763164
282 282 a, g dbSNP:1231058
285 285 c, t dbSNP:757778885
286 286 a, g dbSNP:781769595
308 308 g, t dbSNP:556167865
312 312 a, g dbSNP:750711438
323 323 a, g dbSNP:756538923
325 325 a, g dbSNP:576086958
330 330 c, t dbSNP:749586068
336 336 c, t dbSNP:768721844
360 360 c, t dbSNP:116827208
361 361 a, c, g dbSNP:748242169
362 362 c, g dbSNP:558361531
363 363 g, t dbSNP:776582958
364 364 a, g dbSNP:759222147
367 367 g, t dbSNP:769680774
371 371 a, c dbSNP:775001836
372 372 a, c, t dbSNP:762599546
373 373 a, g, t dbSNP:751062442
376 376 a, c dbSNP:768104416
377 377 a, c dbSNP:750984675
380 380 a, c dbSNP:756417012
382 382 a, g, t dbSNP:775375680
384 384 c, t dbSNP:755138087
385 385 -, gct dbSNP:768874767
391 391 a, g, t dbSNP:779131858
393 393 c, t dbSNP:572253182
406 406 c, t dbSNP:760436733
411 411 a, g dbSNP:540823609
412 412 a, t dbSNP:560861673
413 413 c, t dbSNP:574353637
427 427 c, t dbSNP:769622646
429 429 c, t dbSNP:775296250
430 430 a, g dbSNP:762860833
434 434 c, g dbSNP:768446658
435 435 c, g dbSNP:774184331
449 449 a, g dbSNP:761380927
457 457 a, g dbSNP:767190267
463 463 a, c dbSNP:150243944
477 477 a, g dbSNP:760127893
504 504 a, g dbSNP:756965035
518 518 c, t dbSNP:766872119
519 519 g, t dbSNP:777045969
530 530 a, g dbSNP:759873088
539 539 a, g dbSNP:367810809
552 552 a, t dbSNP:545029257
557 557 g, t dbSNP:765647430
565 565 a, t dbSNP:371989788
573 573 a, g dbSNP:146889423
575 575 a, g dbSNP:764243041
582 582 c, t dbSNP:751617493
588 588 c, t dbSNP:115980353
589 589 g, t dbSNP:780017340
591 591 c, g dbSNP:749292156
597 597 c, t dbSNP:376776365
609 609 c, g dbSNP:544288982
614 614 a, c dbSNP:778787212
620 620 c, t dbSNP:747975037
653 653 a, t dbSNP:771709573
678 678 c, t dbSNP:201389990
680 680 a, c dbSNP:746498149
682 682 a, c dbSNP:770398963
685 685 -, ggc dbSNP:776983383
687 687 c, t dbSNP:777110730
694 694 g, t dbSNP:760103746
697 697 a, g dbSNP:770298297
698 698 g, t dbSNP:775782496
699 699 a, g dbSNP:372404864
704 704 a, c dbSNP:764344642
705 705 a, c dbSNP:751775480
711 711 c, g, t dbSNP:761937649
712 712 g, t dbSNP:750532200
714 714 c, t dbSNP:3742111
715 715 a, g dbSNP:371360518
720 720 c, g, t dbSNP:752503192
721 721 a, g dbSNP:777461016
722 722 c, t dbSNP:746699454
725 725 c, g dbSNP:770470995
726 726 g, t dbSNP:780614099
729 729 a, g dbSNP:745403977
731 731 a, g dbSNP:770244924
734 734 a, g dbSNP:776015477
746 746 c, t dbSNP:763351283
748 748 a, c dbSNP:200388174
753 753 c, t dbSNP:774623623
755 755 a, c dbSNP:761870869
770 770 a, c dbSNP:767869458
777 777 c, g dbSNP:750485389
778 778 c, g dbSNP:760871314
781 781 g, t dbSNP:765237584
787 787 c, g dbSNP:752626603
788 788 c, t dbSNP:758201014
789 789 c, t dbSNP:777495455
791 791 c, t dbSNP:751374189
794 794 a, c dbSNP:756810752
796 796 c, g, t dbSNP:780853213
799 799 -, tcc dbSNP:540409473
800 800 c, t dbSNP:375665681
803 803 c, t dbSNP:570205728
807 807 a, g dbSNP:138515715
811 811 a, g dbSNP:769206811
822 822 g, t dbSNP:189831013
824 824 a, t dbSNP:745424170
830 830 c, g dbSNP:748572460
831 831 a, g dbSNP:572759206
836 836 c, t dbSNP:773610754
838 838 c, t dbSNP:760818419
843 843 a, g dbSNP:766625333
845 845 a, c dbSNP:771549436

Target ORF information:

RefSeq Version NM_145657
Organism Homo sapiens (human)
Definition Homo sapiens GS homeobox 1 (GSX1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_145657

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCCGCGCT CCTTCCTGGT GGACTCGCTA GTGCTGCGCG AGGCGGGCGA GAAGAAGGCG 
CCCGAGGGCA GCCCGCCGCC GCTCTTCCCC TACGCTGTGC CCCCGCCGCA CGCGCTGCAC
GGTCTCTCGC CTGGCGCCTG CCACGCGCGC AAGGCTGGGC TGCTGTGCGT GTGCCCGCTC
TGCGTCACCG CCTCGCAGCT GCATGGGCCC CCCGGGCCGC CCGCGCTGCC TCTACTCAAG
GCTTCCTTCC CACCCTTCGG CTCGCAGTAC TGCCACGCGC CCCTGGGCCG CCAGCACTCT
GCTGTGTCGC CCGGGGTCGC TCACGGCCCG GCCGCCGCTG CTGCTGCCGC CGCGCTCTAC
CAGACCTCCT ACCCGCTGCC TGACCCCAGG CAGTTCCACT GCATCTCTGT GGACAGCAGC
TCTAACCAGC TGCCCAGCAG CAAGAGGATG CGCACGGCTT TCACCAGCAC GCAGCTGCTA
GAGCTGGAGC GCGAGTTCGC TTCTAATATG TACCTGTCCC GCCTACGTCG CATCGAGATC
GCGACCTACC TGAATCTGTC CGAGAAGCAG GTGAAGATCT GGTTTCAGAA CCGCCGAGTG
AAGCACAAGA AGGAGGGCAA GGGCAGCAAC CATCGTGGCG GCGGCGGCGG GGGTGCCGGT
GGTGGCGGGA GCGCACCGCA AGGCTGCAAG TGCGCATCGC TCTCCTCAGC CAAGTGCTCC
GAGGATGACG ACGAATTGCC CATGTCTCCG TCCTCCTCAG GGAAGGACGA CCGGGATCTT
ACGGTCACTC CCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan
Cancer Sci. 104 (8), 1074-1082 (2013)
Low SK, Chung S, Takahashi A, Zembutsu H, Mushiroda T, Kubo M and Nakamura Y.


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Molecular genetic screening of MBS1 locus on chromosome 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative genes in patients with Moebius syndrome
Eur J Med Genet 52 (5), 315-320 (2009)
Uzumcu A, Karaman B, Toksoy G, Uyguner ZO, Candan S, Eris H, Tatli B, Geckinli B, Yuksel A, Kayserili H and Basaran S.


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Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study
Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1369-1378 (2008)
Anney RJ, Lasky-Su J, O'Dushlaine C, Kenny E, Neale BM, Mulligan A, Franke B, Zhou K, Chen W, Christiansen H, Arias-Vasquez A, Banaschewski T, Buitelaar J, Ebstein R, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen H, Asherson P, Faraone SV and Gill M.


book

The DNA sequence and analysis of human chromosome 13
Nature 428 (6982), 522-528 (2004)
Dunham A, Matthews LH, Burton J, Ashurst JL, Howe KL, Ashcroft KJ, Beare DM, Burford DC, Hunt SE, Griffiths-Jones S, Jones MC, Keenan SJ, Oliver K, Scott CE, Ainscough R, Almeida JP, Ambrose KD, Andrews DT, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Bannerjee R, Barlow KF, Bates K, Beasley H, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burrill W, Carder C, Carter NP, Chapman JC, Clamp ME, Clark SY, Clarke G, Clee CM, Clegg SC, Cobley V, Collins JE, Corby N, Coville GJ, Deloukas P, Dhami P, Dunham I, Dunn M, Earthrowl ME, Ellington AG, Faulkner L, Frankish AG, Frankland J, French L, Garner P, Garnett J, Gilbert JG, Gilson CJ, Ghori J, Grafham DV, Gribble SM, Griffiths C, Hall RE, Hammond S, Harley JL, Hart EA, Heath PD, Howden PJ, Huckle EJ, Hunt PJ, Hunt AR, Johnson C, Johnson D, Kay M, Kimberley AM, King A, Laird GK, Langford CJ, Lawlor S, Leongamornlert DA, Lloyd DM, Lloyd C, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, McLaren SJ, McMurray A, Milne S, Moore MJ, Nickerson T, Palmer SA, Pearce AV, Peck AI, Pelan S, Phillimore B, Porter KM, Rice CM, Searle S, Sehra HK, Shownkeen R, Skuce CD, Smith M, Steward CA, Sycamore N, Tester J, Thomas DW, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, Whitehead SL, Willey DL, Wilming L, Wray PW, Wright MW, Young L, Coulson A, Durbin R, Hubbard T, Sulston JE, Beck S, Bentley DR, Rogers J and Ross MT.


book

Homeobox protein Gsh-1-dependent regulation of the rat GHRH gene promoter
Mol. Endocrinol. 15 (12), 2149-2156 (2001)
Mutsuga N, Iwasaki Y, Morishita M, Nomura A, Yamamori E, Yoshida M, Asai M, Ozaki N, Kambe F, Seo H, Oiso Y and Saito H.


 
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