||ORF Nucleotide Sequence (Length: 720bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||fibroblast growth factor 3 precursor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from X14445.1.
This sequence is a reference standard in the RefSeqGene project.
On Sep 6, 2001 this sequence version replaced gi:4885232.
Summary: The protein encoded by this gene is a member of the
fibroblast growth factor (FGF) family. FGF family members possess
broad mitogenic and cell survival activities and are involved in a
variety of biological processes including embryonic development,
cell growth, morphogenesis, tissue repair, tumor growth and
invasion. This gene was identified by its similarity with mouse
fgf3/int-2, a proto-oncogene activated in virally induced mammary
tumors in the mouse. Frequent amplification of this gene has been
found in human tumors, which may be important for neoplastic
transformation and tumor progression. Studies of the similar genes
in mouse and chicken suggested the role in inner ear formation.
[provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC113739.1 [ECO:0000332]
COMPLETENESS: complete on the 3' end.