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FOXE3 forkhead box E3 [Homo sapiens (human)]

Gene Symbol FOXE3
Entrez Gene ID 2301
Full Name forkhead box E3
Synonyms FKHL12, FREAC8
General protein information
Preferred Names
forkhead box protein E3
Names
forkhead box protein E3
FREAC-8
forkhead-related protein FKHL12
forkhead, drosophila, homolog-like 12
forkhead-related transcription factor 8
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p32

Summary This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq, Dec 2009]. lac of sum
Disorder MIM:

601094

Disorder Html: Anterior segment mesenchymal dysgenesis, 107250 (3); Aphakia,





The following FOXE3 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FOXE3 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17850 NM_012186 Homo sapiens forkhead box E3 (FOXE3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $199

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu17850
Accession Version NM_012186.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 960bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 03-MAY-2014
Organism Homo sapiens (human)
Product forkhead box protein E3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF275722.1 and AL607122.20. This sequence is a reference standard in the RefSeqGene project. On Aug 2, 2006 this sequence version replaced gi:11386196. Summary: This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq, Dec 2009]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AF275722.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCGGGGC GCAGCGACAT GGATCCGCCC GCCGCGTTCT CTGGCTTCCC TGCCCTGCCA 
GCGGTCGCGC CGTCGGGGCC GCCGCCGTCG CCGCTCGCAG GAGCCGAGCC AGGGCGGGAG
CCAGAGGAGG CGGCGGCTGG CCGCGGAGAG GCGGCCCCCA CGCCCGCGCC CGGCCCGGGG
CGGCGGCGGC GGCGGCCCCT GCAGCGCGGG AAGCCGCCCT ACTCGTACAT CGCGCTCATC
GCCATGGCTC TGGCGCACGC CCCGGGCCGC CGCCTCACGC TGGCCGCCAT CTACCGCTTC
ATCACCGAAC GCTTTGCCTT CTACCGCGAC AGCCCGCGCA AGTGGCAGAA CAGCATCCGC
CACAATCTCA CGCTCAACGA CTGCTTCGTC AAGGTGCCCC GCGAGCCGGG CAACCCGGGC
AAGGGCAACT ACTGGACGCT GGACCCCGCG GCCGCAGACA TGTTCGACAA CGGCAGCTTC
CTGCGGCGCC GCAAGCGCTT CAAGCGCGCC GAGCTGCCCG CGCACGCGGC CGCGGCGCCA
GGGCCGCCGC TCCCCTTCCC CTACGCGCCC TACGCGCCCG CGCCCGGCCC CGCGCTGCTG
GTGCCGCCGC CTTCTGCCGG ACCGGGCCCC TCGCCGCCCG CGCGTCTGTT CAGCGTCGAC
AGCCTGGTGA ACCTGCAGCC GGAGCTAGCG GGGCTGGGCG CCCCCGAGCC GCCCTGCTGC
GCCGCGCCCG ACGCCGCAGC CGCAGCCTTC CCGCCCTGCG CTGCCGCCGC CTCCCCGCCA
CTCTACTCGC AGGTCCCCGA CCGCCTGGTA CTGCCCGCGA CGCGCCCCGG CCCCGGCCCG
CTGCCCGCTG AGCCCCTCCT GGCCTTGGCC GGGCCGGCAG CCGCTCTCGG CCCGCTCAGC
CCTGGGGAGG CCTACCTGAG GCAGCCGGGC TTCGCGTCGG GGCTGGAGCG CTACCTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_036318.1
CDS245..1204
Misc Feature(1)185..187(+)
Misc Feature(2)455..688(+)
Misc Feature(3)563..667(+)
Exon (1)1..1981
Gene:FOXE3
Gene Synonym:
Translation
Position Chain Variation Link
6 6 -, g dbSNP:774248138
19 19 a, g dbSNP:534842779
56 56 a, g dbSNP:552947867
73 73 a, g dbSNP:148499778
98 98 a, g dbSNP:544944945
120 120 g, t dbSNP:112907775
124 124 a, g dbSNP:556538004
125 125 a, c dbSNP:574923304
128 128 a, g dbSNP:542299729
155 155 g, t dbSNP:115705313
163 163 c, t dbSNP:573328952
164 164 -, g dbSNP:137862650
166 166 a, g dbSNP:549863767
167 167 c, g dbSNP:565396647
168 168 c, g dbSNP:532843709
174 174 c, g dbSNP:551340839
201 201 c, t dbSNP:188265445
213 213 c, g dbSNP:566986648
231 231 a, g dbSNP:181190356
235 235 a, g dbSNP:12760137
241 241 g, t dbSNP:12760142
260 260 a, g dbSNP:765169217
295 295 c, t dbSNP:548368038
390 390 c, g dbSNP:566961335
402 402 c, t dbSNP:534479543
423 423 -, ggc dbSNP:775343166
435 435 a, g dbSNP:751816743
436 436 a, g dbSNP:757496166
450 450 a, g dbSNP:767855430
468 468 a, c dbSNP:750769299
474 474 a, t dbSNP:756484535
475 475 a, c dbSNP:780580886
476 476 a, g dbSNP:377669670
478 478 a, g dbSNP:201158701
484 484 c, t dbSNP:146608794
488 488 a, g dbSNP:746531116
503 503 a, g dbSNP:770527279
513 513 g, t dbSNP:371048362
520 520 c, t dbSNP:143712915
523 523 a, g dbSNP:769513875
524 524 c, t dbSNP:775492512
526 526 a, g dbSNP:762854169
531 531 c, g dbSNP:768651099
532 532 c, t dbSNP:375656937
533 533 a, g dbSNP:774505755
535 535 c, g dbSNP:762006562
541 541 c, t dbSNP:767826050
547 547 c, t dbSNP:750716260
548 548 a, c dbSNP:761097774
550 550 c, g, t dbSNP:376157850
554 554 c, g dbSNP:755377651
555 555 c, g dbSNP:779431323
557 557 c, t dbSNP:751018669
562 562 c, t dbSNP:756805401
568 568 c, t dbSNP:370268389
569 569 c, g dbSNP:780789649
578 578 c, t dbSNP:745571457
581 581 c, t dbSNP:140435664
582 582 c, g, t dbSNP:779654261
584 584 a, c dbSNP:768674287
592 592 c, g dbSNP:774479548
597 597 c, g dbSNP:761953276
603 603 a, g dbSNP:772347736
615 615 c, t dbSNP:773472430
616 616 a, g dbSNP:760754298
622 622 c, t dbSNP:556872254
638 638 a, g dbSNP:754115704
642 642 c, t dbSNP:759971494
646 646 c, t dbSNP:765706567
648 648 a, g dbSNP:372281087
649 649 a, g dbSNP:574859994
652 652 a, g dbSNP:780736595
654 654 a, g dbSNP:749960549
655 655 a, c dbSNP:536267128
656 656 a, c dbSNP:779786518
657 657 a, g dbSNP:373777806
659 659 c, g dbSNP:768612848
660 660 c, t dbSNP:554320597
667 667 a, g dbSNP:145081583
669 669 g, t dbSNP:772151811
674 674 c, t dbSNP:539993865
675 675 a, g dbSNP:747148416
682 682 a, g dbSNP:771014062
683 683 c, t dbSNP:776957243
697 697 c, g dbSNP:759858665
698 698 a, g dbSNP:765655167
701 701 a, c, g dbSNP:367943249
705 705 c, t dbSNP:763391699
710 710 a, g dbSNP:202086896
715 715 c, t dbSNP:749859478
718 718 c, g dbSNP:755671556
725 725 c, t dbSNP:765916151
732 732 a, g dbSNP:753594600
733 733 c, t dbSNP:754808758
735 735 c, g dbSNP:778795099
736 736 c, t dbSNP:747963189
738 738 a, g dbSNP:758373749
740 740 a, c dbSNP:777792086
742 742 a, c dbSNP:747040897
748 748 a, g dbSNP:771078208
751 751 a, c dbSNP:776710407
754 754 c, t dbSNP:34082359
758 758 c, t dbSNP:770015568
760 760 a, g dbSNP:775763975
763 763 c, g dbSNP:577539007
766 766 a, g dbSNP:764459601
771 771 c, t dbSNP:201955081
777 777 c, t dbSNP:760099494
778 778 c, g dbSNP:765973618
781 781 c, g dbSNP:544902810
786 786 a, g dbSNP:754614447
787 787 g, t dbSNP:765016567
794 794 c, t dbSNP:752495188
799 799 c, g dbSNP:758322369
810 810 c, t dbSNP:777536289
816 816 a, g dbSNP:747031780
831 831 c, g dbSNP:281865461
845 845 a, g dbSNP:530072475
849 849 c, t dbSNP:745950487
862 862 c, g dbSNP:189628587
863 863 a, g dbSNP:560327746
873 873 a, c dbSNP:780276474
913 913 g, t dbSNP:749630303
947 947 c, g dbSNP:112802909
964 964 a, c dbSNP:80358194
965 965 a, g dbSNP:774707789
966 966 c, t dbSNP:762325474
976 976 -, gccgca dbSNP:776885332
995 995 c, t dbSNP:772463111
1018 1018 a, c, g, t dbSNP:12724260
1046 1046 c, t dbSNP:776244154
1047 1047 c, g dbSNP:759142626
1075 1075 c, t dbSNP:527783871
1081 1081 c, t dbSNP:752441939
1102 1102 a, c dbSNP:12724403
1103 1103 a, c dbSNP:12724404
1121 1121 a, g dbSNP:762647141
1142 1142 a, g dbSNP:552420470
1173 1173 a, g dbSNP:571095192
1183 1183 a, g dbSNP:538463445
1203 1203 g, t dbSNP:387906793
1213 1213 c, t dbSNP:757149794
1234 1234 a, g dbSNP:776769672
1238 1238 a, t dbSNP:781137229
1239 1239 a, g dbSNP:754472085
1273 1273 a, c dbSNP:550433635
1276 1276 cctctg, tctcta dbSNP:386630974
1276 1276 c, t dbSNP:6666370
1281 1281 a, g dbSNP:2820969
1284 1284 c, t dbSNP:554538370
1410 1410 a, g dbSNP:572796508
1424 1424 a, g dbSNP:533861922
1425 1425 a, c dbSNP:181619150
1469 1469 c, t dbSNP:772458407
1512 1512 c, g dbSNP:776675965
1526 1526 g, t dbSNP:528856611
1554 1554 c, t dbSNP:774081601
1627 1627 -, a dbSNP:148144944
1630 1630 a, c dbSNP:374899294
1633 1633 c, t dbSNP:373095398
1671 1671 c, g dbSNP:74074267
1675 1675 c, t dbSNP:771249977
1683 1683 -, actt dbSNP:201356601
1684 1684 c, g dbSNP:776704164
1719 1719 c, g dbSNP:78460138
1764 1764 a, g dbSNP:765374090
1776 1776 -, t dbSNP:34173190
1794 1794 a, c dbSNP:538648854
1819 1819 -, ctt dbSNP:759478528
1915 1915 c, g dbSNP:186863282
1966 1966 g, t dbSNP:568722651

Target ORF information:

RefSeq Version NM_012186
Organism Homo sapiens (human)
Definition Homo sapiens forkhead box E3 (FOXE3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_012186

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCGGGGC GCAGCGACAT GGATCCGCCC GCCGCGTTCT CTGGCTTCCC TGCCCTGCCA 
GCGGTCGCGC CGTCGGGGCC GCCGCCGTCG CCGCTCGCAG GAGCCGAGCC AGGGCGGGAG
CCAGAGGAGG CGGCGGCTGG CCGCGGAGAG GCGGCCCCCA CGCCCGCGCC CGGCCCGGGG
CGGCGGCGGC GGCGGCCCCT GCAGCGCGGG AAGCCGCCCT ACTCGTACAT CGCGCTCATC
GCCATGGCTC TGGCGCACGC CCCGGGCCGC CGCCTCACGC TGGCCGCCAT CTACCGCTTC
ATCACCGAAC GCTTTGCCTT CTACCGCGAC AGCCCGCGCA AGTGGCAGAA CAGCATCCGC
CACAATCTCA CGCTCAACGA CTGCTTCGTC AAGGTGCCCC GCGAGCCGGG CAACCCGGGC
AAGGGCAACT ACTGGACGCT GGACCCCGCG GCCGCAGACA TGTTCGACAA CGGCAGCTTC
CTGCGGCGCC GCAAGCGCTT CAAGCGCGCC GAGCTGCCCG CGCACGCGGC CGCGGCGCCA
GGGCCGCCGC TCCCCTTCCC CTACGCGCCC TACGCGCCCG CGCCCGGCCC CGCGCTGCTG
GTGCCGCCGC CTTCTGCCGG ACCGGGCCCC TCGCCGCCCG CGCGTCTGTT CAGCGTCGAC
AGCCTGGTGA ACCTGCAGCC GGAGCTAGCG GGGCTGGGCG CCCCCGAGCC GCCCTGCTGC
GCCGCGCCCG ACGCCGCAGC CGCAGCCTTC CCGCCCTGCG CTGCCGCCGC CTCCCCGCCA
CTCTACTCGC AGGTCCCCGA CCGCCTGGTA CTGCCCGCGA CGCGCCCCGG CCCCGGCCCG
CTGCCCGCTG AGCCCCTCCT GGCCTTGGCC GGGCCGGCAG CCGCTCTCGG CCCGCTCAGC
CCTGGGGAGG CCTACCTGAG GCAGCCGGGC TTCGCGTCGG GGCTGGAGCG CTACCTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.