||ORF Nucleotide Sequence (Length: 1245bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||TAR DNA-binding protein 43
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BI464234.1, CD703666.1,
BC001487.2, AL050265.1, AL045296.1, BC059955.1, AF311304.1 and
This sequence is a reference standard in the RefSeqGene project.
On or before Feb 23, 2004 this sequence version replaced
Summary: HIV-1, the causative agent of acquired immunodeficiency
syndrome (AIDS), contains an RNA genome that produces a
chromosomally integrated DNA during the replicative cycle.
Activation of HIV-1 gene expression by the transactivator Tat is
dependent on an RNA regulatory element (TAR) located downstream of
the transcription initiation site. The protein encoded by this gene
is a transcriptional repressor that binds to chromosomally
integrated TAR DNA and represses HIV-1 transcription. In addition,
this protein regulates alternate splicing of the CFTR gene. A
similar pseudogene is present on chromosome 20. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC001487.2, AL050265.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.