The following TARDBP gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TARDBP gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1245bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||TAR DNA-binding protein 43
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BI464234.1, CD703666.1,
BC001487.2, AL050265.1, AL045296.1, BC059955.1, AF311304.1 and
This sequence is a reference standard in the RefSeqGene project.
On or before Feb 23, 2004 this sequence version replaced
Summary: HIV-1, the causative agent of acquired immunodeficiency
syndrome (AIDS), contains an RNA genome that produces a
chromosomally integrated DNA during the replicative cycle.
Activation of HIV-1 gene expression by the transactivator Tat is
dependent on an RNA regulatory element (TAR) located downstream of
the transcription initiation site. The protein encoded by this gene
is a transcriptional repressor that binds to chromosomally
integrated TAR DNA and represses HIV-1 transcription. In addition,
this protein regulates alternate splicing of the CFTR gene. A
similar pseudogene is present on chromosome 20. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC001487.2, AL050265.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.